CO5680415A2 - Procedimiento para preparar un compuesto de azabiciclo [3,1,0]hexano - Google Patents
Procedimiento para preparar un compuesto de azabiciclo [3,1,0]hexanoInfo
- Publication number
- CO5680415A2 CO5680415A2 CO06033239A CO06033239A CO5680415A2 CO 5680415 A2 CO5680415 A2 CO 5680415A2 CO 06033239 A CO06033239 A CO 06033239A CO 06033239 A CO06033239 A CO 06033239A CO 5680415 A2 CO5680415 A2 CO 5680415A2
- Authority
- CO
- Colombia
- Prior art keywords
- hexane
- azabicyclo
- azabiciclo
- hexano
- prepare
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
1.- Un procedimiento para preparar un compuesto de azabiciclo[3.1.0]hexano que tiene menos impurezas que comprende poner en contacto una mezcla que contiene un compuesto de azabiciclo[3.1.0]hexano y al menos una impureza relacionada con el procedimiento en una primera concentración con un alcohol; y recuperar de dicha mezcla dicho compuesto de azabiciclo[3.1.0]hexano, teniendo dicha al menos una impureza relacionada con el procedimiento a una segunda concentración, siendo menor dicha segunda concentración que dicha primera concentración.2.- El procedimiento de la reivindicación 1, en el que dicho compuesto de azabiciclo[3.1.0]hexano es un compuesto de 3-azabiciclo[3.1.0]hexano.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50908803P | 2003-10-06 | 2003-10-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5680415A2 true CO5680415A2 (es) | 2006-09-29 |
Family
ID=34421799
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO06033239A CO5680415A2 (es) | 2003-10-06 | 2006-04-05 | Procedimiento para preparar un compuesto de azabiciclo [3,1,0]hexano |
Country Status (16)
Country | Link |
---|---|
US (1) | US7153976B2 (es) |
EP (1) | EP1678136A1 (es) |
JP (1) | JP2007507484A (es) |
KR (1) | KR100767895B1 (es) |
CN (1) | CN1863772A (es) |
AR (1) | AR046093A1 (es) |
AU (1) | AU2004278159A1 (es) |
BR (1) | BRPI0415062A (es) |
CA (1) | CA2540637A1 (es) |
CO (1) | CO5680415A2 (es) |
IL (1) | IL174415A0 (es) |
MX (1) | MXPA06003811A (es) |
NO (1) | NO20061283L (es) |
RU (1) | RU2006111094A (es) |
TW (1) | TW200526578A (es) |
WO (1) | WO2005033080A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1440059B1 (en) * | 2001-10-22 | 2008-04-16 | Pfizer Products Inc. | 3-azabicyclo(3.1.0)hexane derivatives as opioid receptor antagonists |
SI1725234T1 (sl) | 2004-03-05 | 2013-04-30 | The Trustees Of The University Of Pennsylvania | Postopki zdravljenja nepravilnosti ali bolezni povezanih s hiperlipidemijo in hiperholesterolemijo z minimiziranjem stranskih uäśinkov |
JP2013542929A (ja) | 2010-09-28 | 2013-11-28 | パナセア バイオテック リミテッド | 新規ビシクロ環化合物 |
EP3072884B1 (en) | 2013-11-20 | 2020-01-01 | Sanwa Kagaku Kenkyusho Co., Ltd. | 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purposes |
EP3299357A4 (en) | 2015-05-20 | 2018-11-14 | Sanwa Kagaku Kenkyusho Co., Ltd. | Crystal of salt of novel 3-azabicyclo[3.1.0]hexane derivative and pharmaceutical use thereof |
CN114057627B (zh) * | 2022-01-18 | 2022-04-01 | 南京桦冠生物技术有限公司 | 一种丙型肝炎及新冠药物中间体及其盐的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB948730A (en) | 1959-04-08 | 1964-02-05 | Wellcome Found | Substituted cyclopropanes and related compounds |
US4231935A (en) | 1975-07-31 | 1980-11-04 | American Cyanamid Company | 1-Phenyl-3-azabicyclo[3.1.0]hexanes |
JPH08325228A (ja) * | 1995-05-29 | 1996-12-10 | Sumitomo Chem Co Ltd | ビシクロヘキサンアミン誘導体の製造法 |
EP1440059B1 (en) * | 2001-10-22 | 2008-04-16 | Pfizer Products Inc. | 3-azabicyclo(3.1.0)hexane derivatives as opioid receptor antagonists |
-
2004
- 2004-09-07 US US10/935,442 patent/US7153976B2/en not_active Expired - Fee Related
- 2004-09-27 WO PCT/IB2004/003158 patent/WO2005033080A1/en active Application Filing
- 2004-09-27 AU AU2004278159A patent/AU2004278159A1/en not_active Abandoned
- 2004-09-27 JP JP2006530739A patent/JP2007507484A/ja not_active Withdrawn
- 2004-09-27 CN CNA2004800292396A patent/CN1863772A/zh active Pending
- 2004-09-27 RU RU2006111094/04A patent/RU2006111094A/ru not_active Application Discontinuation
- 2004-09-27 MX MXPA06003811A patent/MXPA06003811A/es not_active Application Discontinuation
- 2004-09-27 BR BRPI0415062-7A patent/BRPI0415062A/pt not_active IP Right Cessation
- 2004-09-27 CA CA002540637A patent/CA2540637A1/en not_active Abandoned
- 2004-09-27 EP EP04769501A patent/EP1678136A1/en not_active Withdrawn
- 2004-09-27 KR KR1020067006539A patent/KR100767895B1/ko not_active IP Right Cessation
- 2004-10-05 TW TW093130167A patent/TW200526578A/zh unknown
- 2004-10-05 AR ARP040103609A patent/AR046093A1/es not_active Application Discontinuation
-
2006
- 2006-03-20 IL IL174415A patent/IL174415A0/en unknown
- 2006-03-21 NO NO20061283A patent/NO20061283L/no not_active Application Discontinuation
- 2006-04-05 CO CO06033239A patent/CO5680415A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20061283L (no) | 2006-06-29 |
JP2007507484A (ja) | 2007-03-29 |
MXPA06003811A (es) | 2006-06-14 |
IL174415A0 (en) | 2006-08-01 |
BRPI0415062A (pt) | 2006-11-28 |
TW200526578A (en) | 2005-08-16 |
US7153976B2 (en) | 2006-12-26 |
KR20060085631A (ko) | 2006-07-27 |
CA2540637A1 (en) | 2005-04-14 |
AR046093A1 (es) | 2005-11-23 |
EP1678136A1 (en) | 2006-07-12 |
KR100767895B1 (ko) | 2007-10-17 |
CN1863772A (zh) | 2006-11-15 |
WO2005033080A1 (en) | 2005-04-14 |
US20050075387A1 (en) | 2005-04-07 |
AU2004278159A1 (en) | 2005-04-14 |
RU2006111094A (ru) | 2006-08-27 |
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Legal Events
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FC | Application refused |