BRPI0415062A - processos para preparar um composto azabiciclo[3.1.0]hexano - Google Patents

processos para preparar um composto azabiciclo[3.1.0]hexano

Info

Publication number
BRPI0415062A
BRPI0415062A BRPI0415062-7A BRPI0415062A BRPI0415062A BR PI0415062 A BRPI0415062 A BR PI0415062A BR PI0415062 A BRPI0415062 A BR PI0415062A BR PI0415062 A BRPI0415062 A BR PI0415062A
Authority
BR
Brazil
Prior art keywords
preparing
processes
azabicyclo
hexane
hexane compound
Prior art date
Application number
BRPI0415062-7A
Other languages
English (en)
Inventor
John J Teixeira
Derek L Tickner
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BRPI0415062A publication Critical patent/BRPI0415062A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

"PROCESSOS PARA PREPARAR UM COMPOSTO AZABICICLO¢3.1.0!HEXANO, BEM COMO SEU SAL". A presente invenção rofere-se a um processo para preparar compostos de azabiciclo¢3.1.0!hexano que têm impurezas reduzidas relacionadas com o processo, por exemplo, derivados de 3-azabicicio¢3.1.0!hexano que têm níveis reduzidos de impurezas etéricas, por exemplo, THF.
BRPI0415062-7A 2003-10-06 2004-09-27 processos para preparar um composto azabiciclo[3.1.0]hexano BRPI0415062A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50908803P 2003-10-06 2003-10-06
PCT/IB2004/003158 WO2005033080A1 (en) 2003-10-06 2004-09-27 Process for preparing an azabicyclo[3.1.0]hexane compound

Publications (1)

Publication Number Publication Date
BRPI0415062A true BRPI0415062A (pt) 2006-11-28

Family

ID=34421799

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415062-7A BRPI0415062A (pt) 2003-10-06 2004-09-27 processos para preparar um composto azabiciclo[3.1.0]hexano

Country Status (16)

Country Link
US (1) US7153976B2 (pt)
EP (1) EP1678136A1 (pt)
JP (1) JP2007507484A (pt)
KR (1) KR100767895B1 (pt)
CN (1) CN1863772A (pt)
AR (1) AR046093A1 (pt)
AU (1) AU2004278159A1 (pt)
BR (1) BRPI0415062A (pt)
CA (1) CA2540637A1 (pt)
CO (1) CO5680415A2 (pt)
IL (1) IL174415A0 (pt)
MX (1) MXPA06003811A (pt)
NO (1) NO20061283L (pt)
RU (1) RU2006111094A (pt)
TW (1) TW200526578A (pt)
WO (1) WO2005033080A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2463264C (en) * 2001-10-22 2009-05-26 Pfizer Products Inc. 3-azabicyclo (3.1.0) hexane derivatives as opioid receptor antagonists
CA2558766A1 (en) 2004-03-05 2005-09-22 The Trustees Of The University Of Pennsylvania The use of mtp inhibitors for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side effects
BR112013007566A2 (pt) 2010-09-28 2016-08-02 Panacea Biotec Ltd novos compostos bicíclicos
DK3072884T3 (da) 2013-11-20 2020-03-09 Sanwa Kagaku Kenkyusho Co 3-azabicyclo[3.1.0]hexanderivat og anvendelse deraf til medicinske formål
EP3299357A4 (en) 2015-05-20 2018-11-14 Sanwa Kagaku Kenkyusho Co., Ltd. Crystal of salt of novel 3-azabicyclo[3.1.0]hexane derivative and pharmaceutical use thereof
CN114057627B (zh) * 2022-01-18 2022-04-01 南京桦冠生物技术有限公司 一种丙型肝炎及新冠药物中间体及其盐的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB948730A (en) 1959-04-08 1964-02-05 Wellcome Found Substituted cyclopropanes and related compounds
US4231935A (en) * 1975-07-31 1980-11-04 American Cyanamid Company 1-Phenyl-3-azabicyclo[3.1.0]hexanes
JPH08325228A (ja) * 1995-05-29 1996-12-10 Sumitomo Chem Co Ltd ビシクロヘキサンアミン誘導体の製造法
CA2463264C (en) * 2001-10-22 2009-05-26 Pfizer Products Inc. 3-azabicyclo (3.1.0) hexane derivatives as opioid receptor antagonists

Also Published As

Publication number Publication date
RU2006111094A (ru) 2006-08-27
EP1678136A1 (en) 2006-07-12
US7153976B2 (en) 2006-12-26
AR046093A1 (es) 2005-11-23
CA2540637A1 (en) 2005-04-14
TW200526578A (en) 2005-08-16
KR100767895B1 (ko) 2007-10-17
MXPA06003811A (es) 2006-06-14
AU2004278159A1 (en) 2005-04-14
JP2007507484A (ja) 2007-03-29
CO5680415A2 (es) 2006-09-29
US20050075387A1 (en) 2005-04-07
NO20061283L (no) 2006-06-29
IL174415A0 (en) 2006-08-01
KR20060085631A (ko) 2006-07-27
CN1863772A (zh) 2006-11-15
WO2005033080A1 (en) 2005-04-14

Similar Documents

Publication Publication Date Title
BRPI0412347A (pt) 2-aminofenil-4-fenilpiridinas como inibidores de quinase
BRPI0813284A8 (pt) Processo para a preparação de um composto da fórmula (i) e composto
BRPI0406926A (pt) Inibidores de polimerase viral
BRPI0410711A (pt) novos compostos
UY29344A1 (es) Anticuerpos antiamiloides humanizados
BRPI0516911A (pt) método para a preparação de um composto e composto de anilina
BRPI0414541A8 (pt) compostos heterocíclicos fundidos, seu uso, método de preparação de compostos intermediários e método para estudar distúrbios mediados por serotonina
GT200300057A (es) Derivados de aminoindazoles, proceso de preparacion e intermediarios de ese proceso a titulos de medicamentos y composiciones farmaceuticas que los concentran
BRPI0411268A (pt) processo para a preparação de um composto 3-aril butil-amina substituìdo
ECSP088773A (es) Derivados de amida y su aplicación para el tratamiento de enfermedades relacionadas con proteína-g
BRPI0712101B8 (pt) ácido beta-fenil-alfa-hidróxi propanóico substituído, método de síntese e uso do mesmo
GT200600217A (es) Proceso para la sintesis de compuestos organicos
BRPI0407282A (pt) Processo para preparação de inibidores de pirrolotriazina cinase
BRPI0610343B8 (pt) composto derivado de morfinan substituído por 7-carbamoíla 6,7-insaturada, composição farmacêutica e uso do mesmo
BRPI0615691A8 (pt) Método para a preparação de 6-((3s,4r)-4-(4-amino-5-cloro-2-metoxibenzamido)-3-metoxipiperidin-1-il) hexanoato de (r)-quinuclidin-3-ila ou sal do mesmo
BR0313831A (pt) Sais benzenossulfonato de derivados de 4-flúor-2-cianopirrolidina
BRPI0606639A2 (pt) novo processo para a preparação de indóis substituìdos
MXPA05011962A (es) Oxiarenos substituidos.
GT200300284A (es) Derivados de 3h-quinazolin-4-ona
BRPI0415062A (pt) processos para preparar um composto azabiciclo[3.1.0]hexano
BRPI0507979A (pt) processo para preparação de um composto
BR0301667A (pt) Processo para a preparação de polìmeros em emulsão com pureza elevada
GB0504103D0 (en) Novel method
BRPI0409235A (pt) processo para a produção de sal de amÈnio do ácido 2-hidróxi-4-metiltiobutìrico
WO2009014203A1 (ja) （１，３，５／２，４，６）－１－フルオロ－２，３，４，５，６－シクロヘキサンペントールの製造方法

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 5A., 6A. E 7A. ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 5A, 6A E 7A ANUIDADES.