CO5611199A2 - Ensayo para anticuerpos anti-ingap - Google Patents

Ensayo para anticuerpos anti-ingap

Info

Publication number
CO5611199A2
CO5611199A2 CO04092294A CO04092294A CO5611199A2 CO 5611199 A2 CO5611199 A2 CO 5611199A2 CO 04092294 A CO04092294 A CO 04092294A CO 04092294 A CO04092294 A CO 04092294A CO 5611199 A2 CO5611199 A2 CO 5611199A2
Authority
CO
Colombia
Prior art keywords
ingap104
peptide
antibody
solid support
detection antibody
Prior art date
Application number
CO04092294A
Other languages
English (en)
Inventor
Aaron L Vinik
David A Taylor-Fisch
Original Assignee
Gmp Endotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gmp Endotherapeutics Inc filed Critical Gmp Endotherapeutics Inc
Publication of CO5611199A2 publication Critical patent/CO5611199A2/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4733Acute pancreatitis-associated protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/474Pancreatic thread protein; Reg protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2410/00Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1.- Un método para detectar anticuerpos contra el péptido INGAP104-118 en una muestra de prueba; el método comprende:poner en contacto una muestra de prueba proveniente de un mamífero con el péptido INGAP104-118 ligado a un soporte sólido, en donde el contacto se realiza en las condiciones suficientes para ligar un anticuerpo anti-INGAP104-118 con el péptido; poner en contacto el soporte sólido con un anticuerpo de detección que específicamente se liga a moléculas de anticuerpos de todos los isotipos de mamíferos; ydeterminar el anticuerpo de detección ligado al soporte sólido, en donde el anticuerpo de detección ligado al soporte sólido indica que la muestra de prueba contiene anticuerpos contra el péptido INGAP104-118.2.- El método de conformidad con la reivindicación 1, caracterizado además porque la cantidad del anticuerpo dedetección ligado se compara con una curva estándar utilizando cantidades conocidas del anticuerpo del péptido anti-INGAP104-118.3.- El método de conformidad con la reivindicación 1, caracterizado además porque el anticuerpo de detección contiene un marcador detectable.
CO04092294A 2002-03-01 2004-09-16 Ensayo para anticuerpos anti-ingap CO5611199A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36104002P 2002-03-01 2002-03-01

Publications (1)

Publication Number Publication Date
CO5611199A2 true CO5611199A2 (es) 2006-02-28

Family

ID=27789061

Family Applications (1)

Application Number Title Priority Date Filing Date
CO04092294A CO5611199A2 (es) 2002-03-01 2004-09-16 Ensayo para anticuerpos anti-ingap

Country Status (17)

Country Link
US (2) US7166439B2 (es)
EP (1) EP1478923A4 (es)
JP (1) JP2005519276A (es)
KR (1) KR20040105738A (es)
CN (1) CN1639572A (es)
AU (1) AU2003216469A1 (es)
BR (1) BR0308095A (es)
CA (1) CA2476979A1 (es)
CO (1) CO5611199A2 (es)
IL (1) IL163580A0 (es)
MA (1) MA27184A1 (es)
MX (1) MXPA04008430A (es)
NO (1) NO20044145L (es)
PL (1) PL373569A1 (es)
RU (1) RU2004129314A (es)
WO (1) WO2003074549A2 (es)
ZA (1) ZA200406877B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090142338A1 (en) * 2005-03-04 2009-06-04 Curedm, Inc. Methods and Compositions for Treating Type 1 and Type 2 Diabetes Mellitus and Related Conditions
EP1858545A2 (en) * 2005-03-04 2007-11-28 Curedm Inc. Methods and pharmaceutical compositions for treating type 1 diabetes mellitus and other conditions
CA2609667C (en) 2005-05-25 2011-02-22 Curedm, Inc. Human proislet peptide, derivatives and analogs thereof, and methods of using same
US8785400B2 (en) * 2006-11-22 2014-07-22 Curedm Group Holdings, Llc Methods and compositions relating to islet cell neogenesis
NZ583679A (en) * 2007-08-30 2012-05-25 Curedm Group Holdings Llc Compositions and methods of using proislet peptides and analogs thereof
WO2009049222A1 (en) * 2007-10-12 2009-04-16 Curedm, Inc. Compositions and methods of using the human proislet peptide receptor
US20090288960A1 (en) * 2008-02-12 2009-11-26 Robert Rubin Rapid Detection of Anti-Chromatin Autoantibodies in Human Serum using a Portable Electrochemical Biosensor
US20160039877A1 (en) 2013-03-15 2016-02-11 Shenzhen Hightide Biopharmaceutical, Ltd. Compositions and methods of using islet neogenesis peptides and analogs thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06506479A (ja) * 1991-11-25 1994-07-21 デイド、インターナショナル、インコーポレイテッド 合成htlv−2ペプチドを用いるイムノアッセイ
US5834590A (en) * 1995-02-22 1998-11-10 Eastern Virginia Medical School Of The Medical College Of Hampton Roads Ingap protein involved in pancreatic islet neogenesis
DE69638315D1 (de) * 1995-02-22 2011-02-17 Eastern Virginia Med School Ingap-protein und dessen beteiligung an der neogenese pankreatischer inselzellen
KR20000052972A (ko) * 1996-10-31 2000-08-25 윌리암 로엘프 드 보에르 유전성의 방사선경화 코팅 조성물 및 상기 코팅재로 피복된 금속 전도체
US6986994B2 (en) * 2001-01-09 2006-01-17 Gmp Endotherapeutics, Inc. INGAP displacement assays

Also Published As

Publication number Publication date
JP2005519276A (ja) 2005-06-30
KR20040105738A (ko) 2004-12-16
ZA200406877B (en) 2005-04-08
IL163580A0 (en) 2005-12-18
BR0308095A (pt) 2006-01-17
WO2003074549A2 (en) 2003-09-12
WO2003074549A3 (en) 2003-12-18
EP1478923A2 (en) 2004-11-24
CN1639572A (zh) 2005-07-13
MA27184A1 (fr) 2005-01-03
MXPA04008430A (es) 2004-11-26
EP1478923A4 (en) 2005-09-21
CA2476979A1 (en) 2003-09-12
US20070184504A1 (en) 2007-08-09
RU2004129314A (ru) 2005-04-20
AU2003216469A1 (en) 2003-09-16
PL373569A1 (en) 2005-09-05
NO20044145L (no) 2004-11-30
US20030166031A1 (en) 2003-09-04
US7166439B2 (en) 2007-01-23

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