CO5261557A1 - Formulacion farmaceutica que comprende 9-[2[[bis[pivaloiloxi metil]fosfono]metoxi]etil]adenina y un excipiente alcalino - Google Patents

Formulacion farmaceutica que comprende 9-[2[[bis[pivaloiloxi metil]fosfono]metoxi]etil]adenina y un excipiente alcalino

Info

Publication number
CO5261557A1
CO5261557A1 CO99077816A CO99077816A CO5261557A1 CO 5261557 A1 CO5261557 A1 CO 5261557A1 CO 99077816 A CO99077816 A CO 99077816A CO 99077816 A CO99077816 A CO 99077816A CO 5261557 A1 CO5261557 A1 CO 5261557A1
Authority
CO
Colombia
Prior art keywords
adenine
bis
ethyl
pivaloiloxi
metoxi
Prior art date
Application number
CO99077816A
Other languages
English (en)
Spanish (es)
Inventor
Terrence C Dahl
J Yuan Lung-Chi
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/211,613 external-priority patent/US6635278B1/en
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of CO5261557A1 publication Critical patent/CO5261557A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
CO99077816A 1998-12-15 1999-12-13 Formulacion farmaceutica que comprende 9-[2[[bis[pivaloiloxi metil]fosfono]metoxi]etil]adenina y un excipiente alcalino CO5261557A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11240398P 1998-12-15 1998-12-15
US09/211,613 US6635278B1 (en) 1998-12-15 1998-12-15 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
CO5261557A1 true CO5261557A1 (es) 2003-03-31

Family

ID=26809911

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99077816A CO5261557A1 (es) 1998-12-15 1999-12-13 Formulacion farmaceutica que comprende 9-[2[[bis[pivaloiloxi metil]fosfono]metoxi]etil]adenina y un excipiente alcalino

Country Status (19)

Country Link
EP (1) EP1140114B1 (ja)
JP (1) JP4750946B2 (ja)
KR (1) KR100624214B1 (ja)
CN (2) CN1202829C (ja)
AR (1) AR021670A1 (ja)
AT (1) ATE298576T1 (ja)
AU (1) AU759869B2 (ja)
BR (1) BRPI9916820B8 (ja)
CA (1) CA2355239C (ja)
CO (1) CO5261557A1 (ja)
DE (1) DE69926012T2 (ja)
ES (1) ES2245130T3 (ja)
HK (1) HK1040488A1 (ja)
ID (1) ID30032A (ja)
MY (1) MY126526A (ja)
NZ (1) NZ511855A (ja)
TR (1) TR200101746T2 (ja)
TW (1) TWI230618B (ja)
WO (1) WO2000035460A2 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535408A (en) * 2000-07-21 2006-09-29 Gilead Sciences Inc Method for selecting prodrugs of phosphonate nucleotide analogues
EP1414435B1 (en) * 2001-07-31 2005-01-12 H. Lundbeck A/S Crystalline composition containing escitalopram
KR20050086519A (ko) * 2002-11-12 2005-08-30 티안진 킨슬리 파마슈티컬 컴퍼니 리미티드 새로운 결정 형태를 가진 아데포비어 디피복실 및 그조성물
WO2004110461A1 (en) 2003-06-13 2004-12-23 Idh Holding Aps Treatment of symptoms associated with bacterial vaginosis
ITMI20071594A1 (it) * 2007-08-02 2009-02-03 Solmag Spa Forma cristallina monoidrata di adefovir dipivoxil
KR20100031045A (ko) 2008-09-11 2010-03-19 씨제이제일제당 (주) 아데포비어 디피복실의 정제방법
CN102149715A (zh) * 2008-09-17 2011-08-10 Cj第一制糖株式会社 肝适能的稳定化固态分散物及其制备方法
KR101089620B1 (ko) * 2009-07-20 2011-12-06 경희대학교 산학협력단 무수결정형 아데포비어 디피복실 및 이온성 액체를 사용한 이의 제조 방법
EP2343056A1 (en) 2009-12-30 2011-07-13 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Producing stable adefovir dipivoxil solid dispersions
WO2016140717A1 (en) 2015-03-04 2016-09-09 Merck Sharp & Dohme Corp. Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
HUE060517T2 (hu) * 2015-12-22 2023-03-28 X4 Pharmaceuticals Inc Immunhiányos betegség kezelésére szolgáló eljárások

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58201726A (ja) * 1982-05-18 1983-11-24 Meiji Seika Kaisha Ltd 安定な製剤の製造法
CS263952B1 (en) * 1985-04-25 1989-05-12 Holy Antonin Remedy with antiviral effect
US4704365A (en) * 1986-02-24 1987-11-03 Abbott Laboratories Composition and method for stabilization of dinucleotides
CA2035841C (en) * 1990-02-22 1996-02-13 Harry B. Demopoulos Storage-stable glucosamine sulphate oral dosage forms and methods for their manufacture
DK0481214T3 (da) * 1990-09-14 1999-02-22 Acad Of Science Czech Republic Prolægemidler af phosphonater
JPH0825905B2 (ja) * 1990-11-20 1996-03-13 武田薬品工業株式会社 医薬固形組成物用安定化剤および安定化方法
HU9203780D0 (en) * 1991-12-12 1993-03-29 Sandoz Ag Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them
SG45369A1 (en) * 1993-01-19 1998-10-16 Warner Lambert Co Stable oral ci-981 formulation and process of preparing same
US5817336A (en) * 1993-04-02 1998-10-06 Orion-Yhtyma Oy Composition containing selegiline
JP2974550B2 (ja) * 1993-06-01 1999-11-10 ビオフェルミン製薬株式会社 経口投与用固体組成物
US5919776A (en) * 1996-12-20 1999-07-06 Merck & Co., Inc. Substituted aminoquinolines as modulators of chemokine receptor activity
JP2762998B2 (ja) * 1997-04-25 1998-06-11 武田薬品工業株式会社 医薬固形組成物用安定化剤および安定化方法
JPH114666A (ja) * 1997-06-17 1999-01-12 Otsuka Pharmaceut Co Ltd マグネシウム補給発泡剤組成物
EP0996430B1 (en) * 1997-07-25 2002-11-27 Gilead Sciences, Inc. Nucleotide analog compositions

Also Published As

Publication number Publication date
WO2000035460A2 (en) 2000-06-22
JP2002532429A (ja) 2002-10-02
CN1202829C (zh) 2005-05-25
CA2355239C (en) 2008-03-18
DE69926012D1 (de) 2005-08-04
MY126526A (en) 2006-10-31
DE69926012T2 (de) 2006-05-04
AU2361300A (en) 2000-07-03
AU759869B2 (en) 2003-05-01
TWI230618B (en) 2005-04-11
JP4750946B2 (ja) 2011-08-17
BRPI9916820B8 (pt) 2023-04-25
TR200101746T2 (tr) 2001-12-21
CN1330547A (zh) 2002-01-09
EP1140114A2 (en) 2001-10-10
CN1682743A (zh) 2005-10-19
NZ511855A (en) 2003-07-25
BRPI9916820B1 (pt) 2018-04-03
KR20010080765A (ko) 2001-08-22
CA2355239A1 (en) 2000-06-22
ATE298576T1 (de) 2005-07-15
KR100624214B1 (ko) 2006-09-18
HK1040488A1 (en) 2002-06-14
CN100361664C (zh) 2008-01-16
ES2245130T3 (es) 2005-12-16
ID30032A (id) 2001-11-01
EP1140114B1 (en) 2005-06-29
BRPI9916820A2 (pt) 2001-10-30
AR021670A1 (es) 2002-07-31
WO2000035460A3 (en) 2000-11-09

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