CO5060487A1 - Anticuerpos anti-idiotipos contra anticuerpos que reconocen gangliosidos portadores de acido sialico n-glicolilado y com posiciones que los contienen - Google Patents

Anticuerpos anti-idiotipos contra anticuerpos que reconocen gangliosidos portadores de acido sialico n-glicolilado y com posiciones que los contienen

Info

Publication number
CO5060487A1
CO5060487A1 CO98060820A CO98060820A CO5060487A1 CO 5060487 A1 CO5060487 A1 CO 5060487A1 CO 98060820 A CO98060820 A CO 98060820A CO 98060820 A CO98060820 A CO 98060820A CO 5060487 A1 CO5060487 A1 CO 5060487A1
Authority
CO
Colombia
Prior art keywords
carriers
synalic
idiotips
glicolilated
gangliosid
Prior art date
Application number
CO98060820A
Other languages
English (en)
Inventor
Lopez Ana Maria Vasquez
Rodriguez Rolando Perez
Sierra Eladio Iglesias
Gonzalez Alexis Perez
Lopez Gumersinda Bombino
Delgado Irene Beausoleil
Original Assignee
Centro Inmunologia Molecular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro Inmunologia Molecular filed Critical Centro Inmunologia Molecular
Publication of CO5060487A1 publication Critical patent/CO5060487A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Anticuerpo monoclonal anti-idiotipo obtenido contraanticuerpos murinos anti-gangliósidos portadores de ácido siálico N-glicolilado.Hibridoma productor del anticuerpo monoclonal de la reivindicación 5 depositado el 29 de Noviembre de 1.997 bajo el número de acceso 97112901, en el Centro para la Microbiología Aplicada (CAMR) ANDamp; Colección Europea de Cultivos Celulares (ECACC), UK.Una composición farmacéutica que contiene una cantidad efectiva del anticuerpo monoclonal anti-idiotipo según las reivindicaciones de la 1 a la 5, con un diluente un adyuvante o una molécula transportadora apropiados.
CO98060820A 1997-10-21 1998-10-20 Anticuerpos anti-idiotipos contra anticuerpos que reconocen gangliosidos portadores de acido sialico n-glicolilado y com posiciones que los contienen CO5060487A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU1997119A CU22702A1 (es) 1997-10-21 1997-10-21 Anticuerpos monoclonales anti - idiotipo, su uso en la inmunoterapia activa de tumores malignos, hibridoma que los produce y composiciones que los contienen

Publications (1)

Publication Number Publication Date
CO5060487A1 true CO5060487A1 (es) 2001-07-30

Family

ID=5459399

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98060820A CO5060487A1 (es) 1997-10-21 1998-10-20 Anticuerpos anti-idiotipos contra anticuerpos que reconocen gangliosidos portadores de acido sialico n-glicolilado y com posiciones que los contienen

Country Status (20)

Country Link
EP (1) EP1027375B1 (es)
JP (1) JP4304287B2 (es)
KR (1) KR100567209B1 (es)
CN (1) CN1210309C (es)
AR (1) AR017369A1 (es)
AT (1) ATE341564T1 (es)
AU (1) AU1019999A (es)
BR (1) BR9812974A (es)
CA (1) CA2308142C (es)
CO (1) CO5060487A1 (es)
CU (1) CU22702A1 (es)
CY (1) CY1105844T1 (es)
DE (1) DE69836096T2 (es)
DK (1) DK1027375T3 (es)
EA (1) EA003366B1 (es)
ES (1) ES2274584T3 (es)
HK (1) HK1034264A1 (es)
PT (1) PT1027375E (es)
SI (1) SI1027375T1 (es)
WO (1) WO1999020656A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU23007A1 (es) * 2001-04-06 2004-12-17 Ct De Inmunologia Molecular Ct De Inmunologia Mole Combinaciones inmunoterapéuticas para el tratamiencombinaciones inmunoterapéuticas para el tratamiento de tumores que sobre-expresan gangliósidos to de tumores que sobre-expresan gangliósidos
WO2011051466A1 (en) * 2009-11-02 2011-05-05 Novartis Ag Anti-idiotypic fibronectin-based binding molecules and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993010221A1 (en) * 1991-11-13 1993-05-27 The Regents Of The University Of California Chimeric murine/human anti-idiotype monoclonal antibodies
US5653977A (en) * 1993-09-09 1997-08-05 Uab Research Foundation Anti-idiotypic antibody that mimics the GD2 antigen
CA2137638C (en) * 1993-12-09 1999-07-20 Ana M. V. Lopez Anti gangliosides monoclonal antibodies and their use in the specific active immunotherapy of malignant tumors
CU22420A1 (es) * 1993-12-29 1996-01-31 Centro Inmunologia Molecular Composicion vacunal para el desarrollo de una respuesta contra gangliosidos n glicolilados y su uso para el tratamiento del cancer
CU22585A1 (es) * 1995-11-17 1999-11-03 Centro Inmunologia Molecular Anticuerpos monoclonales antiidiótipos (ab2) de tipo igg con alta conectividad idiotípica y composiciones farmacéuticas que los contienen. su uso como inmunoreguladores de la respuesta inmune.
US5792455A (en) * 1996-03-21 1998-08-11 Sloan-Kettering Institute For Cancer Research Anti-idiotypic antibody vaccines

Also Published As

Publication number Publication date
SI1027375T1 (sl) 2007-02-28
ATE341564T1 (de) 2006-10-15
EA200000442A1 (ru) 2000-10-30
DE69836096T2 (de) 2007-05-16
EA003366B1 (ru) 2003-04-24
EP1027375B1 (en) 2006-10-04
EP1027375A1 (en) 2000-08-16
KR100567209B1 (ko) 2006-04-03
CN1210309C (zh) 2005-07-13
AR017369A1 (es) 2001-09-05
KR20010031283A (ko) 2001-04-16
BR9812974A (pt) 2000-08-08
CA2308142C (en) 2005-06-14
DE69836096D1 (de) 2006-11-16
HK1034264A1 (en) 2001-10-19
DK1027375T3 (da) 2007-02-05
PT1027375E (pt) 2007-01-31
CA2308142A1 (en) 1999-04-29
JP2001520034A (ja) 2001-10-30
ES2274584T3 (es) 2007-05-16
CU22702A1 (es) 2001-07-31
WO1999020656A1 (es) 1999-04-29
CY1105844T1 (el) 2011-02-02
AU1019999A (en) 1999-05-10
CN1279692A (zh) 2001-01-10
JP4304287B2 (ja) 2009-07-29

Similar Documents

Publication Publication Date Title
Oursler et al. Identification of osteoclast-specific monoclonal antibodies.
Osawa et al. A rat monoclonal antibody that binds specifically to mouse T lymphoblasts and inhibits IL 2 receptor functions: a putative anti-IL 2 receptor antibody.
Knapp et al. VIL-A1, a monoclonal antibody reactive with common acute lymphatic leukemia cells
CO4480042A1 (es) Anticuerpo monoclonal anti alfa-v-integrinas
PE20020972A1 (es) Anticuerpos recombinantes asociados a gangliosidos
ES2441210T5 (es) Asociados de unión del factor de crecimiento placentario, en particular anticuerpos dirigidos contra el factor de crecimiento placentario, su producción y uso
DE60116753D1 (de) Humanisierte antikörper gegen den epidermalen wachstumsfaktorrezeptor
DE69429095D1 (de) Humanisierte antikoerper
DE3580654D1 (de) Menschlicher hybridomfusionspartner zur herstellung menschlicher monoklonaler antikoerper.
ES8609731A1 (es) Un metodo para diagnosticar una condicion neoplastica en un hospedante mamifero
ES2110993T3 (es) Anticuerpos monoclonales especificos para la toxina b de clostridium difficile.
Kodama et al. Monoclonal antibodies to bovine collagenase inhibitor
ES2090085T3 (es) Vacuna contra la coccidiosis.
DE3581288D1 (de) Antileishmania monoklonale antikoerper, diese antikoerper ausscheidende hybridomas, von diesen antikoerpern erkannte leishmaniaantigene, verfahren zur herstellung und verwendung von diesen monoklonalen antikoerpern und antigenen.
ATE115412T1 (de) Anti-idiotyp-antikörper gegen antimenschliche hochmolekulare, an melanomen assoziierte antigene.
CO5060487A1 (es) Anticuerpos anti-idiotipos contra anticuerpos que reconocen gangliosidos portadores de acido sialico n-glicolilado y com posiciones que los contienen
ATE169680T1 (de) 6-o-methylguanin-dna-methyltransferase (mgmt) spezifische antikörper
Kukita et al. Development of a monoclonal antibody to osteoclasts formed in vitro which recognizes mononuclear osteoclast precursors in the marrow
Tharakan et al. Hybridoma growth and antibody secretion in serum-supplemented and low protein serum-free media
ATE75754T1 (de) Monoklonale antikoerper gegen atriale, natriurethische peptide.
FI885169A0 (fi) Monoklonaalinen vasta-aine, joka tunnistaa N-asetyylineuramiinihapon -järjestyksessä, sen käyttö ja sitä tuottava hybridooma
Holman et al. Derivation of monoclonal antibodies against Brucella abortus antigens
DE69533504D1 (de) Monoklonale antikörper gegen antigene, die durch hämatopoietische helferzellen exprimiert werden
DE3783002D1 (de) Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega.
ATE322540T1 (de) Zubereitung für übertragung der aktive tumorspezifische immunisierung von einem immunisiertem allogenem knochenmarkspender