ES8609731A1 - Un metodo para diagnosticar una condicion neoplastica en un hospedante mamifero - Google Patents

Un metodo para diagnosticar una condicion neoplastica en un hospedante mamifero

Info

Publication number
ES8609731A1
ES8609731A1 ES85544389A ES544389A ES8609731A1 ES 8609731 A1 ES8609731 A1 ES 8609731A1 ES 85544389 A ES85544389 A ES 85544389A ES 544389 A ES544389 A ES 544389A ES 8609731 A1 ES8609731 A1 ES 8609731A1
Authority
ES
Spain
Prior art keywords
diagnosis
antibodies
epitope
sialylated lewis
sialylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES85544389A
Other languages
English (en)
Other versions
ES544389A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of ES8609731A1 publication Critical patent/ES8609731A1/es
Publication of ES544389A0 publication Critical patent/ES544389A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products

Abstract

METODO PARA EL DIAGNOSTICO DE ESTADOS NEOPLASTICOS EN HOSPEDANTES MAMIFEROS DE LOS QUE SE SOSPECHA QUE TIENEN NEOPLASIA. CONSISTE EN LA COMBINACION DE UNA MUESTRA BIOLOGICA DEL HOSPEDANTE A DIAGNOSTICAR, TAL COMO UNA MUESTRA DE SUERO O UNA MUESTRA DE TEJIDO, CON UN RECEPTOR ESPECIFICO PARA UN HAPTENO LEX SIALILADO, TAL COMO EL ANTICUERPO MONOCLONAL CSLEX1, PRODUCIDO POR LA CORRESPONDIENTE LINEA CELULAR HIBRIDOMA, CON LO QUE SE FORMA UN COMPLEJO ENTRE EL RECEPTOR MARCADO Y EL HAPTENO; Y DETECCION DE LA PRESENCIA DEL COMPLEJO EN LA MUESTRA BIOLOGICA. ESTE METODO TIENE APLICACIONES PARA LA DIAGNOSIS DE CARCINOMAS DEL ESTOMAGO, COLON Y PANCREAS, Y TUMORES EN EL ESOFAGO, PECHO Y OVARIOS.
ES85544389A 1984-06-21 1985-06-20 Un metodo para diagnosticar una condicion neoplastica en un hospedante mamifero Expired ES8609731A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/623,309 US4752569A (en) 1984-06-21 1984-06-21 Sialylated Lewisx epitope, antibodies and diagnosis

Publications (2)

Publication Number Publication Date
ES8609731A1 true ES8609731A1 (es) 1986-07-16
ES544389A0 ES544389A0 (es) 1986-07-16

Family

ID=24497577

Family Applications (1)

Application Number Title Priority Date Filing Date
ES85544389A Expired ES8609731A1 (es) 1984-06-21 1985-06-20 Un metodo para diagnosticar una condicion neoplastica en un hospedante mamifero

Country Status (5)

Country Link
US (1) US4752569A (es)
EP (1) EP0165811A2 (es)
JP (2) JPH0630618B2 (es)
CA (1) CA1277614C (es)
ES (1) ES8609731A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873188A (en) * 1985-05-28 1989-10-10 Oncogen Method, monoclonal antibody, and monoclonal antibody fragments for detecting human non-small cell lung carcinomas and cell line for producing such antibodies
EP0248147A3 (en) * 1986-03-04 1989-02-15 Sloan-Kettering Institute For Cancer Research Method of determining the presence of cancer cells
NZ222509A (en) * 1986-11-19 1993-03-26 Oncogen Hybridoma cell line producing antibodies binding to tumour-associated mucin antigen
US6004761A (en) * 1986-11-19 1999-12-21 Sanofi Method for detecting cancer using monoclonal antibodies to new mucin epitopes
US5122112A (en) * 1986-11-21 1992-06-16 Imre Corporation Antigen-specific removal of circulating immune complexes
DE3750544D1 (de) * 1986-11-21 1994-10-20 Imre Corp Antigen-spezifisches Entfernen von zirkulierenden Immunokomplexen.
JPS63159763A (ja) * 1986-12-24 1988-07-02 Fujirebio Inc 逆受身凝集反応試薬
EP0287916A1 (en) * 1987-04-13 1988-10-26 Otsuka Pharmaceutical Co., Ltd. Immunoassay
US5403717A (en) * 1987-08-11 1995-04-04 Pacific Northwest Research Diagnosis of premalignant or malignant conditions of human secretory epithelia
WO1989002599A1 (en) * 1987-09-08 1989-03-23 The Biomembrane Institute Detection of survived, undegraded carbohydrate epitopes as diagnostic of intestinal diseases
US5206086A (en) * 1987-10-13 1993-04-27 University Of Rochester Particle-stabilized epitopes for standardization and control of immunoassays
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
US5075218A (en) * 1987-12-29 1991-12-24 Biomira, Inc. Screening for antibodies which bind carbohydrate epitopes of tumor-associated antigens, and uses thereof
EP0380084A3 (en) * 1989-01-27 1991-03-13 The Biomembrane Institute Method for the inhibition of cell-cell and cell substratum interactions by the blocking of carbohydrate-carbohydrate interactions
US5217870A (en) * 1989-04-28 1993-06-08 Biogen, Inc. Monoclonal antibodies against CDX
US6307025B1 (en) 1989-04-28 2001-10-23 Biogen, Inc. VCAM fusion proteins and DNA coding therefor
US5272263A (en) 1989-04-28 1993-12-21 Biogen, Inc. DNA sequences encoding vascular cell adhesion molecules (VCAMS)
WO1992001718A2 (en) * 1990-07-17 1992-02-06 Board Of Regents Of The University Of Oklahoma Functionally active selectin-derived peptides and ligand for gmp-140
BR9106995A (pt) * 1990-11-23 1993-08-24 Gen Hospital Corp Inibicao de interacoes proteina-carboidrato com adesao celular
EP0544898A1 (en) * 1991-06-26 1993-06-09 The Biomembrane Institute Early diagnosis of lung cancer using anti-carbohydrate antibody combinations
SE9102074D0 (sv) * 1991-07-03 1991-07-03 Kabi Pharmacia Ab Tomour antigen specific antibody
WO1994007138A1 (en) 1992-09-14 1994-03-31 Fodstad Oystein Detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations
US5976540A (en) * 1993-05-17 1999-11-02 T Cell Sciences, Inc. Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions
US5856300A (en) * 1994-05-12 1999-01-05 T Cell Sciences, Inc. Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions
DK0730608T3 (da) 1993-05-17 2002-07-22 Avant Immunotherapeutics Inc Præparater omfattende komplementrelaterede proteiner og carbohydrater og fremgangsmåder til fremstilling og anvendelse af præparaterne
NO180658C (no) 1994-03-10 1997-05-21 Oeystein Fodstad Fremgangsmåte og anordning for deteksjon av spesifikke målceller i spesialiserte eller blandede cellepopulasjoner og opplösninger som inneholder blandede cellepopulasjoner
NO961031D0 (no) 1996-03-13 1996-03-13 Det Norske Radiumshospital Tum Fremgangsmåte til å drepe uönskede målceller
US6924359B1 (en) * 1999-07-01 2005-08-02 Yale University Neovascular-targeted immunoconjugates
US20040023415A1 (en) * 2002-03-05 2004-02-05 Konstantin Sokolov Biospecific contrast agents
WO2011046097A1 (ja) * 2009-10-13 2011-04-21 日東紡績株式会社 Ｔ細胞非依存性抗原に対するＩｇＧ型抗体の製造方法、Ｔ細胞非依存性抗原に対するＩｇＧ型抗体を産生する遺伝子組換えカイコおよびその製造方法
US10307471B2 (en) 2013-05-02 2019-06-04 National Institute Of Advanced Industrial Science And Technology Immunity inducer for saccharide antigens

Also Published As

Publication number Publication date
US4752569A (en) 1988-06-21
EP0165811A2 (en) 1985-12-27
ES544389A0 (es) 1986-07-16
JPH0630618B2 (ja) 1994-04-27
CA1277614C (en) 1990-12-11
JPS6163700A (ja) 1986-04-01
JP2950792B2 (ja) 1999-09-20
JPH1052269A (ja) 1998-02-24

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