AR017369A1 - Anticuerpos monoclonales anti-idiotipos, su uso en la inmunoterapia activa de tumores malignos, y composiciones que los contienen - Google Patents

Anticuerpos monoclonales anti-idiotipos, su uso en la inmunoterapia activa de tumores malignos, y composiciones que los contienen

Info

Publication number
AR017369A1
AR017369A1 ARP980105212A ARP980105212A AR017369A1 AR 017369 A1 AR017369 A1 AR 017369A1 AR P980105212 A ARP980105212 A AR P980105212A AR P980105212 A ARP980105212 A AR P980105212A AR 017369 A1 AR017369 A1 AR 017369A1
Authority
AR
Argentina
Prior art keywords
idiotipos
evil
tumors
monoclonal antibodies
compositions containing
Prior art date
Application number
ARP980105212A
Other languages
English (en)
Original Assignee
Centro Inmunologia Molecular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro Inmunologia Molecular filed Critical Centro Inmunologia Molecular
Publication of AR017369A1 publication Critical patent/AR017369A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Anticuerpo monoclonal anti-idiotipo y su uso como inmunomodulador. El anticuerpo monoclonal murino está desarrollado contra un anticuerpo monoclonal murinoque reacciona con gangliosidos portadores de ácido siálico N-glicolilados y con antígenosexpre sados en células tumorales. Se produce un hibridoma productordel anticuerpo. Una composicion farmacéutica que los contiene está destinada a ser utilizada en el tratamiento de neoplasias malignas.
ARP980105212A 1997-10-21 1998-10-20 Anticuerpos monoclonales anti-idiotipos, su uso en la inmunoterapia activa de tumores malignos, y composiciones que los contienen AR017369A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU1997119A CU22702A1 (es) 1997-10-21 1997-10-21 Anticuerpos monoclonales anti - idiotipo, su uso en la inmunoterapia activa de tumores malignos, hibridoma que los produce y composiciones que los contienen

Publications (1)

Publication Number Publication Date
AR017369A1 true AR017369A1 (es) 2001-09-05

Family

ID=5459399

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980105212A AR017369A1 (es) 1997-10-21 1998-10-20 Anticuerpos monoclonales anti-idiotipos, su uso en la inmunoterapia activa de tumores malignos, y composiciones que los contienen

Country Status (20)

Country Link
EP (1) EP1027375B1 (es)
JP (1) JP4304287B2 (es)
KR (1) KR100567209B1 (es)
CN (1) CN1210309C (es)
AR (1) AR017369A1 (es)
AT (1) ATE341564T1 (es)
AU (1) AU1019999A (es)
BR (1) BR9812974A (es)
CA (1) CA2308142C (es)
CO (1) CO5060487A1 (es)
CU (1) CU22702A1 (es)
CY (1) CY1105844T1 (es)
DE (1) DE69836096T2 (es)
DK (1) DK1027375T3 (es)
EA (1) EA003366B1 (es)
ES (1) ES2274584T3 (es)
HK (1) HK1034264A1 (es)
PT (1) PT1027375E (es)
SI (1) SI1027375T1 (es)
WO (1) WO1999020656A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU23007A1 (es) * 2001-04-06 2004-12-17 Ct De Inmunologia Molecular Ct De Inmunologia Mole Combinaciones inmunoterapéuticas para el tratamiencombinaciones inmunoterapéuticas para el tratamiento de tumores que sobre-expresan gangliósidos to de tumores que sobre-expresan gangliósidos
WO2011051466A1 (en) * 2009-11-02 2011-05-05 Novartis Ag Anti-idiotypic fibronectin-based binding molecules and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993010221A1 (en) * 1991-11-13 1993-05-27 The Regents Of The University Of California Chimeric murine/human anti-idiotype monoclonal antibodies
US5653977A (en) * 1993-09-09 1997-08-05 Uab Research Foundation Anti-idiotypic antibody that mimics the GD2 antigen
DE69428763T2 (de) * 1993-12-09 2002-08-01 Ct De Inmunologia Molecular Ci Monoklonale Antikörper gegen Ganglioside und deren Verwendung in der spezifischen, aktiven Immuntherapie gegen bösartige Tumoren
CU22420A1 (es) * 1993-12-29 1996-01-31 Centro Inmunologia Molecular Composicion vacunal para el desarrollo de una respuesta contra gangliosidos n glicolilados y su uso para el tratamiento del cancer
CU22585A1 (es) * 1995-11-17 1999-11-03 Centro Inmunologia Molecular Anticuerpos monoclonales antiidiótipos (ab2) de tipo igg con alta conectividad idiotípica y composiciones farmacéuticas que los contienen. su uso como inmunoreguladores de la respuesta inmune.
US5792455A (en) * 1996-03-21 1998-08-11 Sloan-Kettering Institute For Cancer Research Anti-idiotypic antibody vaccines

Also Published As

Publication number Publication date
SI1027375T1 (sl) 2007-02-28
EP1027375B1 (en) 2006-10-04
EA003366B1 (ru) 2003-04-24
WO1999020656A1 (es) 1999-04-29
CA2308142C (en) 2005-06-14
JP4304287B2 (ja) 2009-07-29
ATE341564T1 (de) 2006-10-15
EP1027375A1 (en) 2000-08-16
ES2274584T3 (es) 2007-05-16
AU1019999A (en) 1999-05-10
DE69836096T2 (de) 2007-05-16
KR100567209B1 (ko) 2006-04-03
CN1279692A (zh) 2001-01-10
CY1105844T1 (el) 2011-02-02
CU22702A1 (es) 2001-07-31
DK1027375T3 (da) 2007-02-05
DE69836096D1 (de) 2006-11-16
CN1210309C (zh) 2005-07-13
CO5060487A1 (es) 2001-07-30
PT1027375E (pt) 2007-01-31
BR9812974A (pt) 2000-08-08
EA200000442A1 (ru) 2000-10-30
JP2001520034A (ja) 2001-10-30
HK1034264A1 (en) 2001-10-19
KR20010031283A (ko) 2001-04-16
CA2308142A1 (en) 1999-04-29

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