CO2021008980A2 - Sistemas activos dinámicos acromosómicos - Google Patents
Sistemas activos dinámicos acromosómicosInfo
- Publication number
- CO2021008980A2 CO2021008980A2 CONC2021/0008980A CO2021008980A CO2021008980A2 CO 2021008980 A2 CO2021008980 A2 CO 2021008980A2 CO 2021008980 A CO2021008980 A CO 2021008980A CO 2021008980 A2 CO2021008980 A2 CO 2021008980A2
- Authority
- CO
- Colombia
- Prior art keywords
- achromosomal
- active systems
- dynamic active
- sadas
- sada
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/08—Reducing the nucleic acid content
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/42—Salmonella
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/44—Staphylococcus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La invención proporciona sistemas activos dinámicos acromosómicos (SADA), incluyendo SADA altamente activos. Estos SADA proporcionados por la invención se pueden obtener mediante una variedad de medios. Se proporcionan diversos métodos de preparación asociados y que usan estos SADA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862777305P | 2018-12-10 | 2018-12-10 | |
PCT/US2019/065562 WO2020123569A1 (en) | 2018-12-10 | 2019-12-10 | Achromosomal dynamic active systems |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2021008980A2 true CO2021008980A2 (es) | 2021-07-30 |
Family
ID=71077548
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2021/0008980A CO2021008980A2 (es) | 2018-12-10 | 2021-07-07 | Sistemas activos dinámicos acromosómicos |
Country Status (15)
Country | Link |
---|---|
US (1) | US20220031862A1 (es) |
EP (1) | EP3893856A4 (es) |
JP (1) | JP2022513709A (es) |
KR (1) | KR20210101260A (es) |
CN (1) | CN113498338A (es) |
AU (1) | AU2019397460A1 (es) |
BR (1) | BR112021011044A2 (es) |
CA (1) | CA3121520A1 (es) |
CL (2) | CL2021001466A1 (es) |
CO (1) | CO2021008980A2 (es) |
EA (1) | EA202191632A1 (es) |
IL (1) | IL283510A (es) |
MX (1) | MX2021006564A (es) |
SG (1) | SG11202105822WA (es) |
WO (1) | WO2020123569A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11649265B2 (en) | 2017-04-28 | 2023-05-16 | Agrospheres, Inc. | Compositions and methods for the encapsulation and scalable delivery of agrochemicals |
US11624061B2 (en) | 2017-04-28 | 2023-04-11 | Agrospheres, Inc. | Compositions and methods for enzyme immobilization |
CN111263814A (zh) | 2017-09-25 | 2020-06-09 | 农业球体公司 | 用于可规模化生产和递送生物制剂的组合物和方法 |
CA3187263A1 (en) * | 2020-06-17 | 2021-12-23 | Flagship Pioneering Innovations Vi, Llc | Adas comprising bacterial secretion systems |
AR122654A1 (es) * | 2020-06-17 | 2022-09-28 | Flagship Pioneering Innovations Vi Llc | Métodos para fabricar adas |
CN112342233B (zh) * | 2020-11-10 | 2022-08-26 | 上海陶宇晟生物技术有限责任公司 | 用于细菌表达DacA时提高c-di-AMP产量的多核苷酸 |
WO2023164454A2 (en) * | 2022-02-22 | 2023-08-31 | Board Of Regents For The Oklahoma Agricultural And Mechanical Colleges | Compositions and methods for improved rhizobium-mediated plant transformation |
WO2023250487A1 (en) | 2022-06-23 | 2023-12-28 | Flagship Pioneering Innovations Vi, Llc | Adas comprising type 1 pili |
CN115851800A (zh) * | 2022-09-20 | 2023-03-28 | 天津大学 | 一种提高希瓦氏菌电子传递能力的方法 |
WO2024107853A1 (en) * | 2022-11-15 | 2024-05-23 | Flagship Pioneering Innovations Vi, Llc | Optimized achromosomal dynamic active systems and uses thereof |
WO2024107843A1 (en) | 2022-11-15 | 2024-05-23 | Flagship Pioneering Innovations Vi, Llc | Stabilized achromosomal dynamic active systems and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030194798A1 (en) * | 2001-05-24 | 2003-10-16 | Surber Mark W. | Minicell compositions and methods |
SI2351772T1 (sl) * | 2005-02-18 | 2016-11-30 | Glaxosmithkline Biologicals Sa | Proteini in nukleinske kisline iz Escherichia coli povezane z meningitisom/sepso |
US9844598B2 (en) * | 2011-12-13 | 2017-12-19 | Engeneic Molecular Delivery Pty Ltd | Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors |
EP2964240B1 (en) * | 2013-03-07 | 2018-10-24 | The General Hospital Corporation | Compositions and methods for bacterial delivery of polypeptides |
US11649265B2 (en) * | 2017-04-28 | 2023-05-16 | Agrospheres, Inc. | Compositions and methods for the encapsulation and scalable delivery of agrochemicals |
-
2019
- 2019-12-10 EP EP19896469.4A patent/EP3893856A4/en active Pending
- 2019-12-10 CA CA3121520A patent/CA3121520A1/en active Pending
- 2019-12-10 JP JP2021531688A patent/JP2022513709A/ja active Pending
- 2019-12-10 MX MX2021006564A patent/MX2021006564A/es unknown
- 2019-12-10 KR KR1020217020753A patent/KR20210101260A/ko unknown
- 2019-12-10 CN CN201980079718.5A patent/CN113498338A/zh active Pending
- 2019-12-10 EA EA202191632A patent/EA202191632A1/ru unknown
- 2019-12-10 WO PCT/US2019/065562 patent/WO2020123569A1/en active Application Filing
- 2019-12-10 US US17/299,377 patent/US20220031862A1/en active Pending
- 2019-12-10 SG SG11202105822WA patent/SG11202105822WA/en unknown
- 2019-12-10 BR BR112021011044-5A patent/BR112021011044A2/pt unknown
- 2019-12-10 AU AU2019397460A patent/AU2019397460A1/en active Pending
-
2021
- 2021-05-27 IL IL283510A patent/IL283510A/en unknown
- 2021-06-03 CL CL2021001466A patent/CL2021001466A1/es unknown
- 2021-07-07 CO CONC2021/0008980A patent/CO2021008980A2/es unknown
-
2023
- 2023-05-30 CL CL2023001550A patent/CL2023001550A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP3893856A1 (en) | 2021-10-20 |
US20220031862A1 (en) | 2022-02-03 |
IL283510A (en) | 2021-07-29 |
SG11202105822WA (en) | 2021-06-29 |
BR112021011044A2 (pt) | 2021-08-31 |
EP3893856A4 (en) | 2022-10-05 |
CL2023001550A1 (es) | 2023-11-03 |
JP2022513709A (ja) | 2022-02-09 |
EA202191632A1 (ru) | 2021-12-06 |
MX2021006564A (es) | 2021-08-11 |
CL2021001466A1 (es) | 2021-11-26 |
AU2019397460A1 (en) | 2021-06-17 |
WO2020123569A1 (en) | 2020-06-18 |
CN113498338A (zh) | 2021-10-12 |
CA3121520A1 (en) | 2020-06-18 |
KR20210101260A (ko) | 2021-08-18 |
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