CO2021005471A2 - Terapia del cáncer con células inmunitarias anti-ptk7 - Google Patents

Terapia del cáncer con células inmunitarias anti-ptk7

Info

Publication number
CO2021005471A2
CO2021005471A2 CONC2021/0005471A CO2021005471A CO2021005471A2 CO 2021005471 A2 CO2021005471 A2 CO 2021005471A2 CO 2021005471 A CO2021005471 A CO 2021005471A CO 2021005471 A2 CO2021005471 A2 CO 2021005471A2
Authority
CO
Colombia
Prior art keywords
ptk7
immune cells
cancer therapy
compositions
malignancies
Prior art date
Application number
CONC2021/0005471A
Other languages
English (en)
Spanish (es)
Inventor
Jonathan Alexander Terrett
Jason Sagert
Original Assignee
Crispr Therapeutics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crispr Therapeutics Ag filed Critical Crispr Therapeutics Ag
Publication of CO2021005471A2 publication Critical patent/CO2021005471A2/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/54—Pancreas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/00—Fusion polypeptide
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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CONC2021/0005471A 2018-11-07 2021-04-27 Terapia del cáncer con células inmunitarias anti-ptk7 CO2021005471A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862756638P 2018-11-07 2018-11-07
US201962910586P 2019-10-04 2019-10-04
PCT/IB2019/059585 WO2020095248A1 (en) 2018-11-07 2019-11-07 Anti-ptk7 immune cell cancer therapy

Publications (1)

Publication Number Publication Date
CO2021005471A2 true CO2021005471A2 (es) 2021-04-30

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CONC2021/0005471A CO2021005471A2 (es) 2018-11-07 2021-04-27 Terapia del cáncer con células inmunitarias anti-ptk7

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US (3) US20210290678A1 (enExample)
EP (1) EP3877421A1 (enExample)
JP (2) JP2022509017A (enExample)
KR (1) KR20210092236A (enExample)
CN (1) CN112955472A (enExample)
AU (1) AU2019374523A1 (enExample)
BR (1) BR112021008083A2 (enExample)
CA (1) CA3118830A1 (enExample)
CO (1) CO2021005471A2 (enExample)
IL (1) IL282532A (enExample)
MX (1) MX2021005400A (enExample)
PH (1) PH12021551047A1 (enExample)
SG (1) SG11202104631SA (enExample)
WO (1) WO2020095248A1 (enExample)
ZA (1) ZA202102745B (enExample)

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US20260078201A1 (en) * 2022-09-06 2026-03-19 Uif (University Industry Foundation), Yonsei University Anti-ptk7 antibody, and use thereof
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CN117085134A (zh) * 2023-07-19 2023-11-21 浙江大学 Ptk7抑制剂在制备预防或治疗肝癌的药物中的用途
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