CO2021002704A2 - Método de producción de precursores neuronales entéricos - Google Patents
Método de producción de precursores neuronales entéricosInfo
- Publication number
- CO2021002704A2 CO2021002704A2 CONC2021/0002704A CO2021002704A CO2021002704A2 CO 2021002704 A2 CO2021002704 A2 CO 2021002704A2 CO 2021002704 A CO2021002704 A CO 2021002704A CO 2021002704 A2 CO2021002704 A2 CO 2021002704A2
- Authority
- CO
- Colombia
- Prior art keywords
- enteric
- enteric neuronal
- production method
- precursor production
- neuronal precursor
- Prior art date
Links
- 230000001537 neural effect Effects 0.000 title abstract 5
- 239000002243 precursor Substances 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229940118471 ErbB-3 agonist Drugs 0.000 abstract 1
- 229940121818 ErbB-4 agonist Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000004498 neuroglial cell Anatomy 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
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Abstract
Resumen un método para producir precursores neuronales entéricos, que comprende los pasos de: (1) proporcionar precursores neuronales entéricos; y (2) se proporciona el cultivo de los precursores neuronales entéricos en un medio que comprende un agonista ERBB3 o un agonista ERBB4 como técnica para permitir que los precursores neuronales entéricos proliferen mediante el cultivo mientras mantienen su capacidad de diferenciación en células nerviosas entéricas y en células gliales.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2018155395 | 2018-08-22 | ||
PCT/JP2019/032543 WO2020040166A1 (ja) | 2018-08-22 | 2019-08-21 | 腸管神経前駆細胞の製造方法 |
Publications (1)
Publication Number | Publication Date |
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CO2021002704A2 true CO2021002704A2 (es) | 2021-04-30 |
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AU2018376391A1 (en) | 2017-11-30 | 2020-06-04 | Kyoto University | Method for culture of cells |
WO2022046771A1 (en) * | 2020-08-24 | 2022-03-03 | The Johns Hopkins University | Juvenile protective factors to arrest and reverse aging in the enteric nervous system |
WO2022236187A1 (en) * | 2021-05-07 | 2022-11-10 | Children's Hospital Los Angeles | Methods for making stem cell-derived enteric neural crest cells and their use in enteric neuropathy treatment |
WO2024009246A1 (en) * | 2022-07-08 | 2024-01-11 | Friedrich Miescher Institute For Biomedical Research | Culture medium suitable for the differentiation and culture of intestinal organoids |
CN117448267A (zh) * | 2023-12-22 | 2024-01-26 | 上海元戊医学技术有限公司 | 一种用于骨关节炎药物的间充质干细胞构建方法与应用 |
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US6890724B2 (en) * | 1996-09-06 | 2005-05-10 | California Institute Of Technology | Methods and compositions for neural progenitor cells |
EP4223769A3 (en) | 2005-12-13 | 2023-11-01 | Kyoto University | Nuclear reprogramming factor |
US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
US7661738B2 (en) | 2006-11-28 | 2010-02-16 | Veritainer Corporation | Radiation detection unit for mounting a radiation sensor to a container crane |
MX348010B (es) | 2007-04-07 | 2017-05-23 | Whitehead Inst Biomedical Res | Reprogramacion de celulas somaticas. |
US20100184051A1 (en) | 2007-05-30 | 2010-07-22 | The General Hospital Corporation | Methods of generating pluripotent cells from somatic cells |
JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
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EP3207123A1 (en) * | 2014-10-17 | 2017-08-23 | Children's Hospital Center D/b/a Cincinnati Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
WO2016104574A1 (ja) | 2014-12-24 | 2016-06-30 | 国立大学法人京都大学 | 異所性骨化の予防・治療剤及びそのスクリーニング方法 |
CN108699528A (zh) | 2015-12-23 | 2018-10-23 | 纪念斯隆-凯特琳癌症中心 | 在先天性巨结肠症中通过衍生自多能干细胞的人肠神经嵴谱系可行的基于细胞的治疗和药物开发 |
CN106367390B (zh) * | 2016-10-12 | 2019-12-31 | 上海爱萨尔生物科技有限公司 | 神经元细胞培养液及培养方法 |
JP6980211B2 (ja) * | 2016-10-21 | 2021-12-15 | 国立大学法人群馬大学 | 末梢神経細胞の製造方法 |
WO2018199142A1 (ja) * | 2017-04-27 | 2018-11-01 | 国立大学法人京都大学 | 神経堤細胞および交感神経細胞の製造方法 |
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AU2018376391A1 (en) * | 2017-11-30 | 2020-06-04 | Kyoto University | Method for culture of cells |
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TW202024322A (zh) | 2020-07-01 |
CN112585262A (zh) | 2021-03-30 |
CN112585262B (zh) | 2023-10-20 |
AU2019326179A8 (en) | 2021-08-26 |
WO2020040166A1 (ja) | 2020-02-27 |
KR20210049779A (ko) | 2021-05-06 |
EP3842525A4 (en) | 2022-07-27 |
SG11202101565XA (en) | 2021-03-30 |
CA3110026A1 (en) | 2020-02-27 |
BR112021003092A2 (pt) | 2021-05-11 |
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