CO2019005955A2 - Preparación farmacéutica y método para su fabricación - Google Patents

Preparación farmacéutica y método para su fabricación

Info

Publication number
CO2019005955A2
CO2019005955A2 CONC2019/0005955A CO2019005955A CO2019005955A2 CO 2019005955 A2 CO2019005955 A2 CO 2019005955A2 CO 2019005955 A CO2019005955 A CO 2019005955A CO 2019005955 A2 CO2019005955 A2 CO 2019005955A2
Authority
CO
Colombia
Prior art keywords
layer
matrix material
preparation
pharmaceutical
composition
Prior art date
Application number
CONC2019/0005955A
Other languages
English (en)
Inventor
Venkata-Rangarao Kanikanti
Patrick Billian
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of CO2019005955A2 publication Critical patent/CO2019005955A2/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • A61P33/12Schistosomicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Una preparación farmacéutica sólida. La presente invención se refiere a una preparación (10) farmacéutica que comprende una primera composición farmacéutica que tiene un material de matriz e ingredientes farmacéuticamente activos que se distribuyen en el material de matriz, en la que la primera composición farmacéutica comprende Praziquantel, Pirantel y Febantel como ingredientes farmacéuticos activos, en la que la preparación (10) comprende una segunda composición farmacéutica que tiene un material de matriz y al menos una de avermectinas y milbemicinas tal como Moxidectina como ingrediente farmacéuticamente activo que se distribuye en el material de matriz, en la que la preparación (10) se proporciona en una estructura de múltiples capas de manera tal que la primera composición se proporciona en una primera capa (12) y la segunda composición se proporciona en una segunda capa (14), en la que la primera capa (12) y la segunda capa (14) se separan mediante una capa (16) barrera que se proporciona entre la primera capa (12) y la segunda capa (14).
CONC2019/0005955A 2016-12-09 2019-06-07 Preparación farmacéutica y método para su fabricación CO2019005955A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16203308 2016-12-09
PCT/EP2017/081049 WO2018104150A1 (en) 2016-12-09 2017-11-30 Pharmaceutical preparation and method for its manufacture

Publications (1)

Publication Number Publication Date
CO2019005955A2 true CO2019005955A2 (es) 2019-06-19

Family

ID=57544274

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2019/0005955A CO2019005955A2 (es) 2016-12-09 2019-06-07 Preparación farmacéutica y método para su fabricación

Country Status (16)

Country Link
US (1) US11382865B2 (es)
EP (1) EP3551173A1 (es)
JP (1) JP2020500898A (es)
KR (1) KR20190093571A (es)
CN (1) CN110022862B (es)
AU (1) AU2017370975A1 (es)
BR (1) BR112019011502A2 (es)
CA (1) CA3046275A1 (es)
CL (1) CL2019001555A1 (es)
CO (1) CO2019005955A2 (es)
DO (1) DOP2019000157A (es)
IL (1) IL266938A (es)
MX (1) MX2019006742A (es)
PH (1) PH12019501249A1 (es)
RU (1) RU2764849C2 (es)
WO (1) WO2018104150A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021006821A2 (pt) * 2018-10-12 2021-07-13 Hovione Scientia Limited método de tratamento de inflamação e patologias oftálmicas, dispersão sólida, formulação farmacêutica, método de matar ácaros e kit

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4999226A (en) 1988-06-01 1991-03-12 Merrell Dow Pharmaceuticals Inc. Pharmaceutical compositions for piperidinoalkanol-ibuprofen combination
US5030622A (en) 1989-06-02 1991-07-09 Merck & Co., Inc. Avermectin derivatives
IT1264517B1 (it) 1993-05-31 1996-09-24 Ekita Investments Nv Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati
DE60118132T2 (de) 2000-10-10 2006-10-19 Wyeth Anthelmintika
US6893652B2 (en) * 2001-08-27 2005-05-17 Wyeth Endoparasiticidal gel composition
IN191024B (es) 2001-09-25 2003-09-13 J B Chemicals And Pharmaceutic
US20040151759A1 (en) * 2002-08-16 2004-08-05 Douglas Cleverly Non-animal product containing veterinary formulations
TWI366442B (en) 2003-07-30 2012-06-21 Novartis Ag Palatable ductile chewable veterinary composition
US7396819B2 (en) 2003-08-08 2008-07-08 Virbac Corporation Anthelmintic formulations
WO2005084688A1 (fr) 2004-03-04 2005-09-15 Yuwan Wang Poudre injectable contenant un vermifuge
US20060024368A1 (en) 2004-07-30 2006-02-02 Reza Fassihi Compressed composite delivery system for release-rate modulation of bioactives
WO2006036624A2 (en) 2004-09-24 2006-04-06 The Hartz Mountain Corporation Lipid stabilized formulations
US7348027B2 (en) 2005-04-08 2008-03-25 Bayer Healthcare Llc Taste masked veterinary formulation
NZ580357A (en) * 2007-05-07 2011-06-30 Jurox Pty Ltd Chewable gelatinised protein dosage form and process
US20080293645A1 (en) 2007-05-25 2008-11-27 Schneider Lawrence F Antiparasitic combination and method for treating domestic animals
BR112014013371B1 (pt) 2011-12-02 2020-04-07 Merial Ltd formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
HU231017B1 (hu) 2012-05-08 2019-11-28 LAVET Gyógyszeripari Kft. Praziquantel tartalmú ízfedett formulációk
MX2015007640A (es) 2012-12-19 2015-09-23 Bayer Animal Health Gmbh Comprimidos que tienen aceptacion mejorada y buena estabilidad durante el almacenamiento.
WO2015071668A1 (en) * 2013-11-14 2015-05-21 Cipla Limited Pharmaceutical compositions
WO2018065826A1 (en) * 2016-10-06 2018-04-12 Sucampo Ag Multilayer beads for pharmaceutical use

Also Published As

Publication number Publication date
IL266938A (en) 2019-07-31
CN110022862B (zh) 2022-05-24
EP3551173A1 (en) 2019-10-16
CA3046275A1 (en) 2018-06-14
WO2018104150A1 (en) 2018-06-14
US20200069591A1 (en) 2020-03-05
JP2020500898A (ja) 2020-01-16
MX2019006742A (es) 2019-09-05
US11382865B2 (en) 2022-07-12
AU2017370975A1 (en) 2019-05-30
RU2019121235A3 (es) 2021-02-16
PH12019501249A1 (en) 2019-12-02
BR112019011502A2 (pt) 2019-11-05
CN110022862A (zh) 2019-07-16
RU2764849C2 (ru) 2022-01-21
DOP2019000157A (es) 2019-07-15
KR20190093571A (ko) 2019-08-09
RU2019121235A (ru) 2021-01-12
CL2019001555A1 (es) 2019-10-25

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