CO2017011238A2 - Anticuerpos anti-c1s humanizados - Google Patents

Anticuerpos anti-c1s humanizados

Info

Publication number
CO2017011238A2
CO2017011238A2 CONC2017/0011238A CO2017011238A CO2017011238A2 CO 2017011238 A2 CO2017011238 A2 CO 2017011238A2 CO 2017011238 A CO2017011238 A CO 2017011238A CO 2017011238 A2 CO2017011238 A2 CO 2017011238A2
Authority
CO
Colombia
Prior art keywords
antibodies
humanized anti
present description
description provides
nucleic acids
Prior art date
Application number
CONC2017/0011238A
Other languages
English (en)
Inventor
Graham Parry
Sandip Panicker
Original Assignee
Bioverativ Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioverativ Usa Inc filed Critical Bioverativ Usa Inc
Publication of CO2017011238A2 publication Critical patent/CO2017011238A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21106—Hepsin (3.4.21.106)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

La presente descripción proporciona anticuerpos anti-C1s humanizados. La presente descripción proporciona ácidos nucleicos que comprenden secuencias de nucleótidos que codifican los anticuerpos anti-C1s humanizados; y las células hospedadoras que comprenden los ácidos nucleicos. La presente descripción proporciona composiciones que comprenden los anticuerpos anti-C1s humanizados. La presente descripción proporciona métodos de uso de los anticuerpos anti-C1s humanizados.
CONC2017/0011238A 2015-04-06 2017-10-31 Anticuerpos anti-c1s humanizados CO2017011238A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562143636P 2015-04-06 2015-04-06
US201562200997P 2015-08-04 2015-08-04
PCT/US2016/026038 WO2016164358A1 (en) 2015-04-06 2016-04-05 Humanized anti-c1s antibodies and methods of use thereof

Publications (1)

Publication Number Publication Date
CO2017011238A2 true CO2017011238A2 (es) 2018-01-16

Family

ID=57073330

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0011238A CO2017011238A2 (es) 2015-04-06 2017-10-31 Anticuerpos anti-c1s humanizados

Country Status (27)

Country Link
US (3) US10729767B2 (es)
EP (2) EP4212175A1 (es)
JP (3) JP7005483B2 (es)
KR (1) KR20180006379A (es)
CN (2) CN108348598B (es)
AU (2) AU2016246452B2 (es)
BR (1) BR112017021289A2 (es)
CA (1) CA2981321A1 (es)
CL (1) CL2017002514A1 (es)
CO (1) CO2017011238A2 (es)
DK (1) DK3280440T3 (es)
EA (1) EA201792080A1 (es)
ES (1) ES2938359T3 (es)
FI (1) FI3280440T3 (es)
HK (2) HK1250930A1 (es)
HR (1) HRP20230093T1 (es)
HU (1) HUE061076T2 (es)
IL (2) IL298180A (es)
LT (1) LT3280440T (es)
MX (2) MX2017012834A (es)
PH (1) PH12017501815A1 (es)
PL (1) PL3280440T3 (es)
PT (1) PT3280440T (es)
RS (1) RS63956B1 (es)
SG (2) SG10201909180SA (es)
SI (1) SI3280440T1 (es)
WO (1) WO2016164358A1 (es)

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US11267868B2 (en) 2013-04-02 2022-03-08 Chugai Seiyaku Kabushiki Kaisha Fc region variant
RS63956B1 (sr) 2015-04-06 2023-02-28 Bioverativ Usa Inc Humanizovana anti-c1s antitela i metode njihove upotrebe
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Also Published As

Publication number Publication date
US11246926B2 (en) 2022-02-15
JP2018513213A (ja) 2018-05-24
MX2022001085A (es) 2022-02-14
HRP20230093T1 (hr) 2023-03-31
SG10201909180SA (en) 2019-11-28
ES2938359T3 (es) 2023-04-10
US20200405852A1 (en) 2020-12-31
JP2021006544A (ja) 2021-01-21
HK1259251A1 (zh) 2019-11-29
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EA201792080A1 (ru) 2018-03-30
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