CO2017003488A2 - Nuevo complejo hidróxido de hierro (iii) con jarabes de glucosa activados y procedimiento para su preparación - Google Patents
Nuevo complejo hidróxido de hierro (iii) con jarabes de glucosa activados y procedimiento para su preparaciónInfo
- Publication number
- CO2017003488A2 CO2017003488A2 CONC2017/0003488A CO2017003488A CO2017003488A2 CO 2017003488 A2 CO2017003488 A2 CO 2017003488A2 CO 2017003488 A CO2017003488 A CO 2017003488A CO 2017003488 A2 CO2017003488 A2 CO 2017003488A2
- Authority
- CO
- Colombia
- Prior art keywords
- iii
- activated
- iron
- glucose syrup
- procedure
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Abstract
La presente invención se refiere generalmente a complejos de hidratos de carbono de hierro (III) ya procedimientos para su fabricación. El producto obtenible de acuerdo con el método de la presente invención puede usarse de forma segura para la población general o animales en la terapia de deficiencia de hierro. El procedimiento de la invención incluye las etapas de (i) proporcionar una solución acuosa de jarabe de glucosa que tiene un cierto equivalente de dextrosa (DE), (ii) añadir uno o más agentes blanqueadores oxidantes, obteniendo de este modo el jarabe de glucosa activado; (iii) convertir dicho jarabe de glucosa activado en un complejo con hidróxido de hierro (III); Y (iv) obtener un complejo de hidróxido de hierro (III) y jarabe de glucosa activado.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14386023.7A EP2997968A1 (en) | 2014-09-22 | 2014-09-22 | Iron (III) hydroxide complexes with activated glucose syrups and process for preparing same |
| PCT/EP2015/067216 WO2016045826A1 (en) | 2014-09-22 | 2015-07-28 | Iron (iii) hydroxide complexes with activated glucose syrups and process for preparing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2017003488A2 true CO2017003488A2 (es) | 2017-07-11 |
Family
ID=51730477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2017/0003488A CO2017003488A2 (es) | 2014-09-22 | 2017-04-10 | Nuevo complejo hidróxido de hierro (iii) con jarabes de glucosa activados y procedimiento para su preparación |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US20170232040A1 (es) |
| EP (3) | EP2997968A1 (es) |
| AP (1) | AP2017009747A0 (es) |
| AU (1) | AU2015320003C1 (es) |
| BR (1) | BR112017005614A2 (es) |
| CA (1) | CA2956870C (es) |
| CL (1) | CL2017000690A1 (es) |
| CO (1) | CO2017003488A2 (es) |
| CY (1) | CY1122133T1 (es) |
| DK (1) | DK3197444T3 (es) |
| EA (1) | EA033807B1 (es) |
| ES (1) | ES2740630T3 (es) |
| GE (1) | GEP20197004B (es) |
| HR (1) | HRP20191458T1 (es) |
| HU (1) | HUE044803T2 (es) |
| IL (1) | IL250615A0 (es) |
| LT (1) | LT3197444T (es) |
| MA (2) | MA50202A (es) |
| MX (1) | MX368219B (es) |
| MY (1) | MY187900A (es) |
| PE (1) | PE20170689A1 (es) |
| PH (1) | PH12017500316B1 (es) |
| PL (1) | PL3197444T3 (es) |
| PT (1) | PT3197444T (es) |
| RS (1) | RS59246B1 (es) |
| SA (2) | SA517381133B1 (es) |
| SG (1) | SG11201701408TA (es) |
| SI (1) | SI3197444T1 (es) |
| WO (1) | WO2016045826A1 (es) |
| ZA (1) | ZA201701899B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR1009597B (el) | 2018-04-16 | 2019-09-16 | Ιουλια Κλεωνος Τσετη | Φαρμακευτικο σκευασμα για την ενισχυση των επιπεδων σιδηρου στο αιμα, που περιεχει πολυμαλτοζικο σιδηρο (ιιι) και μια δραστικη ουσια επιλεγμενη απο πενταϋδρικο φυλλινικο ασβεστιο, βιταμινη c ή συνδυασμο των δυο, που ενισχυει την απορροφηση σιδηρου |
| TWI784646B (zh) * | 2021-07-29 | 2022-11-21 | 台耀化學股份有限公司 | 製備羧基麥芽糖鐵的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2885393A (en) | 1956-02-24 | 1959-05-05 | R K Laros Company | Dextran-iron complex and process for making same |
| US3076798A (en) | 1961-02-23 | 1963-02-05 | Hausmann Lab Ltd | Process for preparing a ferric hydroxide polymaltose complex |
| DE1293144B (de) | 1964-11-04 | 1969-04-24 | Hausmann Ag Labor | Verfahren zur Herstellung von Komplexverbindungen des Eisens mit Sorbit, Gluconsaeure und einem Oligosaccharid |
| ZA711254B (en) | 1970-03-13 | 1971-11-24 | Fisons Ltd | Treatment of iron deficiency in piglets |
| US3908004A (en) | 1970-05-20 | 1975-09-23 | C L Basingstoke Limited | Process for making injectable iron compositions for treating iron-deficiency anemia |
| US4180567A (en) | 1977-09-02 | 1979-12-25 | Pharmachem Corporation | Iron preparations and methods of making and administering the same |
| DE3422249A1 (de) | 1984-06-15 | 1985-12-19 | Pfeifer & Langen, 5000 Köln | Wasserloesliches eisendextran und verfahren zu seiner herstellung |
| GB9514090D0 (en) | 1995-07-11 | 1995-09-13 | Cerestar Holding Bv | Non-catalysed oxidation of maltodextrin with an oxygen containing oxidant |
| JP4520748B2 (ja) | 2002-04-09 | 2010-08-11 | ファーマコスモス、ホールディング、アクティーゼルスカブ | 鉄欠乏性貧血の治療のための鉄デキストリン化合物 |
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| ITMO20050056A1 (it) | 2005-03-15 | 2006-09-16 | Biofer Spa | Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi. |
-
2014
- 2014-09-22 EP EP14386023.7A patent/EP2997968A1/en not_active Withdrawn
-
2015
- 2015-07-28 EA EA201790673A patent/EA033807B1/ru unknown
- 2015-07-28 HU HUE15739647 patent/HUE044803T2/hu unknown
- 2015-07-28 GE GEAP201514478A patent/GEP20197004B/en unknown
- 2015-07-28 SG SG11201701408TA patent/SG11201701408TA/en unknown
- 2015-07-28 MY MYPI2017700471A patent/MY187900A/en unknown
- 2015-07-28 PT PT15739647T patent/PT3197444T/pt unknown
- 2015-07-28 PE PE2017000252A patent/PE20170689A1/es unknown
- 2015-07-28 MX MX2017003708A patent/MX368219B/es active IP Right Grant
- 2015-07-28 EP EP15739647.4A patent/EP3197444B1/en active Active
- 2015-07-28 SI SI201530847T patent/SI3197444T1/sl unknown
- 2015-07-28 MA MA050202A patent/MA50202A/fr unknown
- 2015-07-28 WO PCT/EP2015/067216 patent/WO2016045826A1/en active Application Filing
- 2015-07-28 AU AU2015320003A patent/AU2015320003C1/en active Active
- 2015-07-28 RS RSP20191009 patent/RS59246B1/sr unknown
- 2015-07-28 DK DK15739647.4T patent/DK3197444T3/da active
- 2015-07-28 MA MA40322A patent/MA40322B1/fr unknown
- 2015-07-28 CA CA2956870A patent/CA2956870C/en active Active
- 2015-07-28 LT LT15739647T patent/LT3197444T/lt unknown
- 2015-07-28 AP AP2017009747A patent/AP2017009747A0/en unknown
- 2015-07-28 BR BR112017005614A patent/BR112017005614A2/pt not_active Application Discontinuation
- 2015-07-28 EP EP19182379.8A patent/EP3583941A1/en active Pending
- 2015-07-28 US US15/513,006 patent/US20170232040A1/en not_active Abandoned
- 2015-07-28 ES ES15739647T patent/ES2740630T3/es active Active
- 2015-07-28 PL PL15739647T patent/PL3197444T3/pl unknown
-
2017
- 2017-02-15 IL IL250615A patent/IL250615A0/en active IP Right Grant
- 2017-02-21 PH PH12017500316A patent/PH12017500316B1/en unknown
- 2017-03-17 ZA ZA2017/01899A patent/ZA201701899B/en unknown
- 2017-03-19 SA SA517381133A patent/SA517381133B1/ar unknown
- 2017-03-19 SA SA518392070A patent/SA518392070B1/ar unknown
- 2017-03-22 CL CL2017000690A patent/CL2017000690A1/es unknown
- 2017-04-10 CO CONC2017/0003488A patent/CO2017003488A2/es unknown
-
2019
- 2019-08-09 CY CY20191100860T patent/CY1122133T1/el unknown
- 2019-08-12 HR HRP20191458 patent/HRP20191458T1/hr unknown
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