CO2017002070A2 - Un proceso para la preparación de derivados de 3-fenil/heteroaril-6-fenoxi-8-alquilamino-imidazo[1,2-b] piridazina - Google Patents

Un proceso para la preparación de derivados de 3-fenil/heteroaril-6-fenoxi-8-alquilamino-imidazo[1,2-b] piridazina

Info

Publication number
CO2017002070A2
CO2017002070A2 CONC2017/0002070A CO2017002070A CO2017002070A2 CO 2017002070 A2 CO2017002070 A2 CO 2017002070A2 CO 2017002070 A CO2017002070 A CO 2017002070A CO 2017002070 A2 CO2017002070 A2 CO 2017002070A2
Authority
CO
Colombia
Prior art keywords
preparation
imidazo
alkylamino
phenoxy
heteroaryl
Prior art date
Application number
CONC2017/0002070A
Other languages
English (en)
Inventor
Holger Paulsen
Uwe Münster
Nicolas Guimond
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of CO2017002070A2 publication Critical patent/CO2017002070A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00—Formation or introduction of functional groups containing oxygen
    • C07B41/02—Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Métodos para preparar compuestos imidazopiridazina sustituidos de fórmula general (I) como se describe y define en la presente, así como también compuestos intermediarios útiles para la preparación de dichos compuestos
CONC2017/0002070A 2014-09-01 2017-03-01 Un proceso para la preparación de derivados de 3-fenil/heteroaril-6-fenoxi-8-alquilamino-imidazo[1,2-b] piridazina CO2017002070A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14183029 2014-09-01
PCT/EP2015/069739 WO2016034507A1 (en) 2014-09-01 2015-08-28 A process for the preparation of 3-phenyl/heteroaryl-6-phenoxy-8-alkylamino-imidazo[1,2-b]pyridazine derivatives

Publications (1)

Publication Number Publication Date
CO2017002070A2 true CO2017002070A2 (es) 2017-05-19

Family

ID=51422014

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0002070A CO2017002070A2 (es) 2014-09-01 2017-03-01 Un proceso para la preparación de derivados de 3-fenil/heteroaril-6-fenoxi-8-alquilamino-imidazo[1,2-b] piridazina

Country Status (19)

Country Link
US (1) US20170305912A1 (es)
EP (1) EP3189055A1 (es)
JP (1) JP2017525725A (es)
KR (1) KR20170044166A (es)
CN (1) CN106795164A (es)
AR (1) AR101730A1 (es)
AU (1) AU2015311011A1 (es)
BR (1) BR112017003916A2 (es)
CA (1) CA2959224A1 (es)
CO (1) CO2017002070A2 (es)
IL (1) IL250264A0 (es)
MX (1) MX2017002749A (es)
PE (1) PE20170447A1 (es)
RU (1) RU2017110880A (es)
SG (1) SG11201700818XA (es)
TW (1) TW201613927A (es)
UY (1) UY36284A (es)
WO (1) WO2016034507A1 (es)
ZA (1) ZA201702297B (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070078136A1 (en) 2005-09-22 2007-04-05 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
TW201107329A (en) * 2009-07-30 2011-03-01 Oncotherapy Science Inc Fused imidazole derivative having ttk inhibitory action
TWI541243B (zh) 2010-09-10 2016-07-11 拜耳知識產權公司 經取代咪唑并嗒
WO2014020041A1 (en) * 2012-08-02 2014-02-06 Bayer Pharma Aktiengesellschaft Combinations for the treatment of cancer
CA2890861C (en) 2012-11-21 2021-03-30 Raqualia Pharma Inc. Polymorphic forms of 4-{[4-({[4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazol-3-yl]oxy}methyl)piperidin-1-yl]methyl}-tetrahydro-2h-pyran-4-carboxylic acid
TW201437211A (zh) * 2013-03-01 2014-10-01 Bayer Pharma AG 經取代咪唑并嗒□
MA38657A1 (fr) * 2013-06-13 2018-05-31 Bayer Pharma AG Combinaison d'un dérivé d'imidazopyridazine et d'un agent mitotique pour le traitement du cancer

Also Published As

Publication number Publication date
WO2016034507A1 (en) 2016-03-10
TW201613927A (en) 2016-04-16
PE20170447A1 (es) 2017-05-18
JP2017525725A (ja) 2017-09-07
RU2017110880A (ru) 2018-10-03
CA2959224A1 (en) 2016-03-10
CN106795164A (zh) 2017-05-31
EP3189055A1 (en) 2017-07-12
AU2015311011A1 (en) 2017-02-23
BR112017003916A2 (pt) 2018-03-06
MX2017002749A (es) 2017-07-26
US20170305912A1 (en) 2017-10-26
KR20170044166A (ko) 2017-04-24
IL250264A0 (en) 2017-03-30
UY36284A (es) 2016-04-01
ZA201702297B (en) 2018-12-19
SG11201700818XA (en) 2017-03-30
AR101730A1 (es) 2017-01-11

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