SG11201700818XA - A process for the preparation of 3-phenyl/heteroaryl-6-phenoxy-8-alkylamino-imidazo[1,2-b]pyridazine derivatives - Google Patents

A process for the preparation of 3-phenyl/heteroaryl-6-phenoxy-8-alkylamino-imidazo[1,2-b]pyridazine derivatives

Info

Publication number
SG11201700818XA
SG11201700818XA SG11201700818XA SG11201700818XA SG11201700818XA SG 11201700818X A SG11201700818X A SG 11201700818XA SG 11201700818X A SG11201700818X A SG 11201700818XA SG 11201700818X A SG11201700818X A SG 11201700818XA SG 11201700818X A SG11201700818X A SG 11201700818XA
Authority
SG
Singapore
Prior art keywords
imidazo
alkylamino
phenoxy
heteroaryl
phenyl
Prior art date
Application number
SG11201700818XA
Inventor
Holger Paulsen
Uwe Münster
Nicolas Guimond
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of SG11201700818XA publication Critical patent/SG11201700818XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00Formation or introduction of functional groups containing oxygen
    • C07B41/02Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SG11201700818XA 2014-09-01 2015-08-28 A process for the preparation of 3-phenyl/heteroaryl-6-phenoxy-8-alkylamino-imidazo[1,2-b]pyridazine derivatives SG11201700818XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14183029 2014-09-01
PCT/EP2015/069739 WO2016034507A1 (en) 2014-09-01 2015-08-28 A process for the preparation of 3-phenyl/heteroaryl-6-phenoxy-8-alkylamino-imidazo[1,2-b]pyridazine derivatives

Publications (1)

Publication Number Publication Date
SG11201700818XA true SG11201700818XA (en) 2017-03-30

Family

ID=51422014

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201700818XA SG11201700818XA (en) 2014-09-01 2015-08-28 A process for the preparation of 3-phenyl/heteroaryl-6-phenoxy-8-alkylamino-imidazo[1,2-b]pyridazine derivatives

Country Status (19)

Country Link
US (1) US20170305912A1 (en)
EP (1) EP3189055A1 (en)
JP (1) JP2017525725A (en)
KR (1) KR20170044166A (en)
CN (1) CN106795164A (en)
AR (1) AR101730A1 (en)
AU (1) AU2015311011A1 (en)
BR (1) BR112017003916A2 (en)
CA (1) CA2959224A1 (en)
CO (1) CO2017002070A2 (en)
IL (1) IL250264A0 (en)
MX (1) MX2017002749A (en)
PE (1) PE20170447A1 (en)
RU (1) RU2017110880A (en)
SG (1) SG11201700818XA (en)
TW (1) TW201613927A (en)
UY (1) UY36284A (en)
WO (1) WO2016034507A1 (en)
ZA (1) ZA201702297B (en)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070078136A1 (en) 2005-09-22 2007-04-05 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
TW201107329A (en) 2009-07-30 2011-03-01 Oncotherapy Science Inc Fused imidazole derivative having ttk inhibitory action
TWI541243B (en) 2010-09-10 2016-07-11 拜耳知識產權公司 Substituted imidazopyridazines
WO2014020041A1 (en) * 2012-08-02 2014-02-06 Bayer Pharma Aktiengesellschaft Combinations for the treatment of cancer
EP2922849B1 (en) 2012-11-21 2017-07-12 RaQualia Pharma Inc. Polymorphs of 4-{[4-({[4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazol-3-yl]oxy}methyl)piperidin-1-yl]methyl}-tetrahydro-2h-pyran-4-carboxylic acid as 5-hydroxytryptamine-4 (5-ht4) receptor agonists for the treatment of gastrointestinal diseases
TW201437211A (en) 2013-03-01 2014-10-01 Bayer Pharma AG Substituted imidazopyridazines
CN105392484A (en) * 2013-06-13 2016-03-09 拜耳制药股份公司 Combination of a imidazopyridazine derivative and a mitotic agent for the treatment of cancer

Also Published As

Publication number Publication date
EP3189055A1 (en) 2017-07-12
US20170305912A1 (en) 2017-10-26
CA2959224A1 (en) 2016-03-10
ZA201702297B (en) 2018-12-19
RU2017110880A (en) 2018-10-03
JP2017525725A (en) 2017-09-07
AR101730A1 (en) 2017-01-11
PE20170447A1 (en) 2017-05-18
CN106795164A (en) 2017-05-31
MX2017002749A (en) 2017-07-26
WO2016034507A1 (en) 2016-03-10
UY36284A (en) 2016-04-01
KR20170044166A (en) 2017-04-24
BR112017003916A2 (en) 2018-03-06
CO2017002070A2 (en) 2017-05-19
AU2015311011A1 (en) 2017-02-23
TW201613927A (en) 2016-04-16
IL250264A0 (en) 2017-03-30

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