CN2601094Y - Compound capsule - Google Patents

Compound capsule Download PDF

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Publication number
CN2601094Y
CN2601094Y CN 03235197 CN03235197U CN2601094Y CN 2601094 Y CN2601094 Y CN 2601094Y CN 03235197 CN03235197 CN 03235197 CN 03235197 U CN03235197 U CN 03235197U CN 2601094 Y CN2601094 Y CN 2601094Y
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CN
China
Prior art keywords
capsule
complex
interior
solid
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN 03235197
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Chinese (zh)
Inventor
吕爱平
罗晓健
龚建平
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangxi Bencao Tiangong Technology Co Ltd
Original Assignee
Jiangxi Bencao Tiangong Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangxi Bencao Tiangong Technology Co Ltd filed Critical Jiangxi Bencao Tiangong Technology Co Ltd
Priority to CN 03235197 priority Critical patent/CN2601094Y/en
Application granted granted Critical
Publication of CN2601094Y publication Critical patent/CN2601094Y/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The utility model relates to a capsule, in particular to a composite capsule that can be separately filled with the solid and the liquid elements at the same time. The utility model adopts the technology proposal that the composite capsule comprises an external capsule, one or a plurality of internal capsule; the internal capsule is positioned inside the external capsule; the external capsule is filled with the solid element and the internal capsule is filled with the liquid element; and the solid elements surrounds the internal capsule; the volatile oil liquid part and the water soluble solid element are separated, thereby reducing the mutual action and extending the saving time, without the need to convert into solid and liquid suspension liquid. The device greatly reduces application of solubilizer and excipient and other non-medicine material and thus reduces the cost.

Description

Complex capsule
Technical field
This utility model relates to a kind of capsule, and particularly a kind of complex capsule can be separated simultaneously and load solid and liquid composition.
Background technology
General hard capsule is used to fill the solid composition, and Western medicine is many to be occurred with solid powder form; For aqueous pharmaceutical compositions, external pharmaceutical manufacturer is solidified into it fine particle usually and is encapsulated in the hard capsule again, perhaps aqueous medicine is wrapped up with soft capsule; But seldom have solid composition and liquid composition are filled in same complex capsule simultaneously, this is because Western medicine mostly is chemical industry or biosynthesis, seldom relate to crude vegetal, the traditional medicine volatile oil composition.Therefore external capsule technique is seldom considered Chinese Chinese medicine, and the situation of volatile oil and aqueous solvent two big class active ingredients is arranged in the natural plants field, and present also do not have suitable complex capsule to preserve this two big class active ingredient simultaneously.
Only will be filled in the capsule after Chinese medicine or the curing of natural plant water-soluble material, the active ingredient with in the loss traditional medicine volatile oil causes the loss on resource and the curative effect; But the solid-liquid suspension dosage form is made in volatile oil and water-soluble solid active ingredient to be encapsulated in the same capsule again, occurring aqueous oiliness two big class materials unavoidably interacts, and influence the situation of drug effect, and the volatile oil curing technology of employing Western medicine, the consumption of the inert matter of non-pharmaceutical compositions will be increased greatly, increase cost, be similarly uniform solid-liquid suspension dosage form, need to add the solubilizing agent of a large amount of non-pharmaceutical compositions, need to increase cost equally, the requirement of above-mentioned figuration and suspension technology is very high, production equipment, and the requirement of operating cost all is that conventional pharmaceutical manufacturer is unapproachable.
Summary of the invention
This utility model purpose provides a kind of complex capsule that can separate preservation solid and liquid composition simultaneously, can reduce cost.
The technical solution of the utility model is: a kind of complex capsule comprises an outer capsule, one or more interior capsules, it is characterized in that: interior capsule is positioned at outer capsule, the solid composition is housed in the outer capsule, the liquid composition is housed in the interior capsule, the solid composition is wrapped in around the interior capsule.
Optimized technical scheme has following:
Complex capsule, its outer capsule is a form of hard gelatin capsules.
Complex capsule, its outer capsule is the soft capsule form.
Complex capsule, capsule is a form of hard gelatin capsules in it.
Complex capsule, capsule is the soft capsule form in it.
Complex capsule, capsule is a dripping pill type in it.
The Chinese medicine water soluble ingredient of dress solid dosage forms in the complex capsule, its outer capsule, dress traditional medicine volatile oil composition in the interior capsule.
The natural plant water-soluble composition of dress solid dosage forms in the complex capsule, its outer capsule, dress natural plant volatile oil composition in the interior capsule.
The present invention adopts conventional technology to extract the volatile oil of Chinese medicine or natural plants, in institute's volatile oil of carrying is enclosed in volatile oil with the drop pill of routine or soft capsule containing technology; The present invention is to the water-soluble portion of Chinese medicine or natural plants, extract with conventional water extraction, again the water solublity water extract is solidified, filling technique with routine is filled into it in outer capsule, and be filled with the outer capsule of solid, water soluble composition can be in advance or fill drop pill or the soft capsule that the oily composition that evaporates is housed afterwards.
Advantage of the present utility model is: volatile oil liquid part and water-soluble solid composition are separated, can reduce the interaction between them, prolonged the holding time, do not need to make the solid-liquid suspension form, can reduce in a large number or without the application of other non-excipient substances such as solubilizing agent and excipient, thereby reduce cost.
Description of drawings
Fig. 1 is the structural representation of the complex capsule of hard capsule for the outer capsule of this utility model.
Fig. 2 is the structural representation of the complex capsule of soft capsule for the outer capsule of this utility model.
The specific embodiment
Embodiment 1
A kind of complex capsule comprises an outer capsule 1, one or more interior capsules 2, and it is characterized in that: interior capsule 2 is positioned at outer capsule 1, in the outer capsule 1 solid composition 4 is housed, and in the interior capsule 2 liquid composition 3 is housed, and solid composition 4 is wrapped in around the interior capsule 2.
Embodiment 2
Complex capsule, its outer capsule 1 is a hard capsule 1a form.All the other are with embodiment 1.
Embodiment 3
Complex capsule, its outer capsule 1 is a soft capsule 1b form.All the other are with embodiment 1.
Embodiment 4
Complex capsule, capsule 2 is a hard capsule 2a form in it.All the other are with embodiment 1.
Embodiment 5
Complex capsule, capsule 2 is a soft capsule 2b form in it.All the other are with embodiment 1.
Embodiment 6
Complex capsule, capsule 2 is a drop pill 2c form in it.All the other are with embodiment 1.
Embodiment 7
Complex capsule, the Chinese medicine water soluble ingredient of dress solid dosage forms in its outer capsule 1, dress traditional medicine volatile oil composition in the interior capsule 2.All the other are with embodiment 1.
Embodiment 8
Complex capsule, the natural plant water-soluble composition of dress solid dosage forms in its outer capsule 1, dress natural plant volatile oil composition in the interior capsule 2.All the other are with embodiment 1.
Embodiment 9
Complex capsule, outer capsule 1 are any one in No. 000,00,0,1,2,3,4, the hard capsule model.All the other are with embodiment 1.
Embodiment 10, complex capsule, interior capsule 2 weight are less than 100mg.All the other are with embodiment 1.
Embodiment 11, complex capsule, interior capsule 2 weight 20-50mg.All the other are with embodiment 1.
Embodiment 12,
The part of complex capsule is loaded specification:
Volatile oil is made the drop pill of 100,70,60,50,40,20,10,2 milligrams of all sizes.
Volatile oil is made the soft capsule of 100,70,60,50,40,20,10,2 milligrams of kind of specifications.
Volatile oil is made the hard capsule of No. 0,1,2,3,4, kind of specification.
In No. 1 hard capsule, load one 100 or 70 or 60 or 50 or 40 milligrams drop pill.
In No. 1 hard capsule, load one 100 or 70 or 60 or 50 or 40 milligrams soft capsule.
In No. 0 hard capsule, load three 20 milligrams drop pill.
In No. 0 hard capsule, load three 20 milligrams drop pill, two 10 milligrams soft capsule.
In No. 00 hard capsule, load three 20 milligrams drop pill, two 10 milligrams soft capsule, one 2
Number volatile oil hard capsule.
Embodiment 13, complex capsule, the ageratum Chinese medicine water soluble ingredient of dress solid dosage forms in its outer capsule 1, dress ageratum traditional medicine volatile oil composition in the interior capsule 2.All the other are with embodiment 1.
Complex capsule, nine gas of dress solid dosage forms are twisted with the fingers pain ball Chinese medicine water soluble ingredient in its outer capsule 1, adorn nine gas in the interior capsule 2 and twist with the fingers pain ball traditional medicine volatile oil composition.All the other are with embodiment 1.
Complex capsule, seven flavor Fructus Choerospondiatis ball Chinese medicine water soluble ingredients of dress solid dosage forms are adorned seven flavor Fructus Choerospondiatis ball traditional medicine volatile oil compositions in its outer capsule 1 in the interior capsule 2.All the other are with embodiment 1.
Complex capsule, the liquorice beverage soluble components of dress solid dosage forms in its outer capsule 1, dress Radix Glycyrrhizae volatile oil component in the interior capsule 2.All the other are with embodiment 1.
Complex capsule, the ginseng water-soluble composition of dress solid dosage forms in its outer capsule 1, dress ginseng essential oil composition in the interior capsule 2.All the other are with embodiment 1.

Claims (10)

1, a kind of complex capsule, comprise an outer capsule (1), capsule (2) in one or more, it is characterized in that: interior capsule (2) is positioned at outer capsule (1), solid composition (4) is housed in the outer capsule (1), liquid composition (3) is housed in the interior capsule (2), and solid composition (4) is wrapped in interior capsule (2) all around.
2, complex capsule according to claim 1 is characterized in that: outer capsule (1) is hard capsule (1a) form.
3, complex capsule according to claim 1 is characterized in that: outer capsule (1) is soft capsule (1b) form.
4, complex capsule according to claim 1 is characterized in that: interior capsule (2) is hard capsule (2a) form.
5, complex capsule according to claim 1 is characterized in that: interior capsule (2) is soft capsule (2b) form.
6, complex capsule according to claim 1 is characterized in that: interior capsule (2) is drop pill (2c) form.
7, complex capsule according to claim 1 is characterized in that: the Chinese medicine water soluble ingredient of dress solid dosage forms in the outer capsule (1), dress traditional medicine volatile oil composition in the interior capsule (2).
8, complex capsule according to claim 1 is characterized in that: the natural plant water-soluble composition of dress solid dosage forms in the outer capsule (1), dress natural plant volatile oil composition in the interior capsule (2).
9, complex capsule according to claim 2 is characterized in that: outer capsule (1) is in No. 000,00,0,1,2,3,4, the hard capsule model any one.
10, according to claim 4 or 5 or 6 described complex capsules, it is characterized in that: interior capsule (2) weight 20-50mg.
CN 03235197 2003-01-08 2003-01-08 Compound capsule Expired - Fee Related CN2601094Y (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 03235197 CN2601094Y (en) 2003-01-08 2003-01-08 Compound capsule

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 03235197 CN2601094Y (en) 2003-01-08 2003-01-08 Compound capsule

Publications (1)

Publication Number Publication Date
CN2601094Y true CN2601094Y (en) 2004-01-28

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 03235197 Expired - Fee Related CN2601094Y (en) 2003-01-08 2003-01-08 Compound capsule

Country Status (1)

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CN (1) CN2601094Y (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100350897C (en) * 2003-01-08 2007-11-28 江西本草天工科技有限责任公司 Two-phase hard capsule and its application
CN104302278A (en) * 2012-03-29 2015-01-21 塞拉拜姆有限责任公司 Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
CN106963742A (en) * 2016-11-07 2017-07-21 澳门大学 Chinese medicine solid-liquid capsule and preparation method thereof
US9907755B2 (en) 2013-03-14 2018-03-06 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
CN108348399A (en) * 2015-10-29 2018-07-31 通用电气健康护理有限公司 Screening arrangement

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100350897C (en) * 2003-01-08 2007-11-28 江西本草天工科技有限责任公司 Two-phase hard capsule and its application
CN104302278A (en) * 2012-03-29 2015-01-21 塞拉拜姆有限责任公司 Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
US10588857B2 (en) 2012-03-29 2020-03-17 Therabiome, Llc Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
US9907755B2 (en) 2013-03-14 2018-03-06 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
US10369111B2 (en) 2013-03-14 2019-08-06 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
US11590083B2 (en) 2013-03-14 2023-02-28 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
CN108348399A (en) * 2015-10-29 2018-07-31 通用电气健康护理有限公司 Screening arrangement
CN106963742A (en) * 2016-11-07 2017-07-21 澳门大学 Chinese medicine solid-liquid capsule and preparation method thereof
CN106963742B (en) * 2016-11-07 2021-02-23 澳门大学 Chinese medicine solid-liquid capsule and its preparation method

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C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20040128

Termination date: 20100208