CN220676524U - Nasal sprayer for improving deposition rate of medicine sniffing area - Google Patents
Nasal sprayer for improving deposition rate of medicine sniffing area Download PDFInfo
- Publication number
- CN220676524U CN220676524U CN202221815835.9U CN202221815835U CN220676524U CN 220676524 U CN220676524 U CN 220676524U CN 202221815835 U CN202221815835 U CN 202221815835U CN 220676524 U CN220676524 U CN 220676524U
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- China
- Prior art keywords
- nozzle
- liquid outlet
- medicine
- deposition rate
- outlet pipe
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- 239000003814 drug Substances 0.000 title claims abstract description 41
- 230000008021 deposition Effects 0.000 title claims abstract description 20
- 239000007788 liquid Substances 0.000 claims abstract description 48
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000000428 dust Substances 0.000 claims description 7
- 239000004743 Polypropylene Substances 0.000 claims description 3
- -1 polypropylene Polymers 0.000 claims description 3
- 229920001155 polypropylene Polymers 0.000 claims description 3
- 239000007922 nasal spray Substances 0.000 claims 6
- 229940097496 nasal spray Drugs 0.000 claims 6
- 229940126601 medicinal product Drugs 0.000 claims 5
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- 229940127557 pharmaceutical product Drugs 0.000 claims 2
- 238000005507 spraying Methods 0.000 abstract description 9
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 229940079593 drug Drugs 0.000 description 9
- 239000007921 spray Substances 0.000 description 6
- 230000008499 blood brain barrier function Effects 0.000 description 5
- 210000001218 blood-brain barrier Anatomy 0.000 description 5
- 208000014644 Brain disease Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 210000003813 thumb Anatomy 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 2
- 210000003169 central nervous system Anatomy 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000003928 nasal cavity Anatomy 0.000 description 2
- 210000002850 nasal mucosa Anatomy 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 208000032274 Encephalopathy Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 210000003140 lateral ventricle Anatomy 0.000 description 1
- 210000001365 lymphatic vessel Anatomy 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000000492 nasalseptum Anatomy 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicinal Preparation (AREA)
Abstract
The utility model discloses a nasal sprayer for improving the deposition rate of a medicine sniffing zone, which comprises a liquid outlet pipe 1, a water core 2 and a nozzle 3, wherein the liquid outlet pipe 1 is bent at a certain angle, and the angle is between 90 and 180 degrees; one end of the liquid outlet pipe 1 is connected with the nozzle 3, and the other end of the liquid outlet pipe 1 is connected with an external liquid medicine source; one end of the nozzle 3 is provided with a liquid outlet, the other end is provided with a limiting device 4, and the distance between the liquid outlet of the nozzle 3 and the limiting device 4 is 20 mm-30 mm; the end face of the liquid outlet of the nozzle 3 is arc-shaped; the novel nasal sprayer for improving the deposition rate of the medicine olfactory region can keep the medicine source of the nasal sprayer upright, and is more beneficial to spraying and spraying of medicine liquid; and when the patient is at home to apply by oneself, the nasal part is gone into in assurance that can be accurate, makes the liquid medicine can more accurate location in the district of sniffing, has improved the treatment of liquid medicine.
Description
Technical Field
The utility model relates to a medical appliance, in particular to a nasal sprayer for improving the deposition rate of a medicine olfactory region.
Background
The blood brain barrier is the most important bottleneck of the drug to play a central disease treatment role, and the drug cannot effectively cross the blood brain barrier, so that the drug cannot play a brain disease treatment role.
Due to the presence of the Blood Brain Barrier (BBB), existing routes of administration, such as oral, intravenous, intramuscular, subcutaneous, etc., are not effective in delivering drugs to the Central Nervous System (CNS). In addition, as the amount of drug administered increases, systemic side effects also increase.
The central administration route includes lateral ventricle administration (ICV), direct injection of brain parenchyma, etc., and although targeting is good, the medicine can be directly delivered to the injured brain area to exert curative effect, and complications such as infection may occur after the operation due to traumatism of the cone-cranium operation. In addition, the existing central administration route is high in cost, the economic burden of patients is excessive, and wide application is impractical for thousands of encephalopathy patients. Therefore, finding a central administration route that avoids the blood brain barrier obstruction is the most central problem for drugs to exert the actual therapeutic effect of brain diseases.
The administration through nasal mucosa is considered as a rapid and efficient administration mode, and there are many fine villi on the nasal mucosa cells, so the effective area for drug absorption is greatly increased, there are abundant blood vessels and lymphatic vessels under the mucosal cells, and the drug can directly enter the systemic circulation after being absorbed through the mucosa, and in addition, the metabolism of the enzyme in the nasal cavity is far smaller than that of the gastrointestinal tract, so the nasal administration system is increasingly receiving attention.
The nasal sprayer in the prior art cannot be accurately positioned to the olfactory region, and the medicine source of the nasal sprayer is difficult to keep upright, so that the parallelism caused by uneven spraying is poor, and when a patient is in home for self-treatment, the nose entering part is difficult to accurately grasp, so that the treatment effect is difficult to reach expectations.
Disclosure of Invention
In view of this, the utility model provides a nasal sprayer for improving the deposition rate of a medicine sniffing zone, which comprises a liquid outlet pipe 1, a water core 2 and a nozzle 3, wherein the water core 2 is arranged in the nozzle 3, one end of the nozzle 3 is provided with a liquid outlet, one end of the liquid outlet pipe 1 is connected with the nozzle 3, the other end of the liquid outlet pipe 1 is connected with an external medicine liquid source, the liquid outlet pipe 1, the water core 2 and the nozzle 3 form a channel for spraying medicine liquid, and the liquid outlet pipe 1 is arranged in a bent shape with a certain angle A.
Preferably, the angle A of the bent liquid outlet pipe 1 is more than 90 degrees and less than 180 degrees; more preferably 120 to 150, for example 125 °, 130 °, 135 °, 140 °, 145 °.
Preferably, the outlet end face of the nozzle 3 is arranged in an arc shape.
Preferably, the other end of the nozzle 3 is provided with a stop means 4, preferably the stop means 4 is of a length greater than the diameter of the nostril.
Preferably, the distance from the outlet of the nozzle 3 to the limiting device 4 is 20mm to 30mm, more preferably 22mm to 28mm, still more preferably 24mm to 26mm; most preferably 25mm.
Preferably, the nozzle 3 is also provided with a removable dust cap 5.
Preferably, the liquid outlet pipe 1, the nozzle 3 and the dust cap 5 are made of polypropylene.
The beneficial effects of the utility model are as follows: the novel nasal sprayer for improving the deposition rate of the medicine sniffing zone is adopted, and the liquid outlet pipe is arranged in a bent shape, so that the medicine source part of the nasal sprayer can be kept upright during administration, the problem of poor parallelism caused by uneven spraying is solved, the medicine liquid can be more accurately positioned in the sniffing zone, and the deposition rate of the medicine in the sniffing zone is improved; the design of the nozzle limiting device can solve the problem that the drug effect is reduced because the length of the nasal part is difficult to accurately control when a patient self-administers drug.
Drawings
In order to more clearly illustrate the technical solutions of the present utility model or the technical solutions of the prior art, the drawings that are needed in the embodiments or the description of the prior art will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present utility model, and that it is within the scope of the present utility model to those skilled in the art to obtain other drawings from these drawings without inventive effort.
FIG. 1 is a schematic diagram of the structure of the present utility model;
fig. 2 is an exploded view of the structure of the present utility model.
Detailed Description
In order that the utility model may be readily understood, a more complete description of the utility model will be rendered by reference to the appended drawings. One embodiment of the present utility model is shown in the drawings. This utility model may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth in the figures and described below. Rather, the detailed description is provided to provide a more thorough and complete understanding of the present disclosure.
In the following description of the specific embodiments, some well-known functions and constructions are not described in detail for brevity. It should be appreciated that in the development of any such actual embodiment, numerous implementation details must be made to achieve the developer's specific goals, such as compliance with system-related and business-related constraints, which will vary from one implementation to another. In addition, it will be appreciated that such a development effort might be complex and time-consuming, but would nevertheless be a routine undertaking for those of ordinary skill in the art.
It is further noted that the drawings are in a very simplified form and utilize non-precise ratios, and are merely provided to facilitate a convenient, clear, and helpful description of the embodiments of the present utility model. The utility model is described in further detail below with reference to the drawings.
The utility model provides a nasal sprayer for improving the deposition rate of a medicine sniffing zone, which is shown in figures 1 and 2 and comprises a liquid outlet pipe 1, a water core 2 and a nozzle 3, wherein the water core 2 is arranged in the nozzle 3, and one end of the nozzle 3 is provided with a liquid outlet; one end of the liquid outlet pipe 1 is connected with the nozzle 3, the other end of the liquid outlet pipe 1 is connected with an external liquid medicine source, and the liquid outlet pipe 1, the water core 2 and the nozzle 3 form a channel for spraying liquid medicine; the outlet pipe 1 is arranged in a bent shape with a certain angle a. In the present utility model, the storage device of the external liquid medicine source may be a liquid medicine storage device or device well known in the art, and may include a nozzle, a pressure pump, a liquid storage bottle, etc., so as to limit the spraying of the medicine when pressing or using the medicine. The liquid outlet pipe 1 is bent, and the angle a is any angle between 90 ° and 180 °, so as to be capable of meeting the requirement that the liquid medicine storage device or equipment keeps upright without inclination, preferably 120 ° to 150 °, for example, 125 °, 130 °, 135 °, 140 °, 145 °.
In other embodiments of the utility model, the other end of the nozzle 3 is provided with a limiting device 4, and the length of the limiting device 4 is larger than the diameter of the nostril; in other embodiments of the present utility model, the limiting device may be configured in various shapes, such as round, square, to provide a limiting function and aesthetic limitation.
In other embodiments of the utility model, the distance from the liquid outlet of the nozzle 3 to the limiting device 4 is between 20mm and 30mm; preferably, the diameter is 22mm to 28mm, more preferably 24mm to 26mm; most preferably 25mm.
In a further embodiment of the utility model, the outlet end face of the nozzle 3 is provided with a cambered surface to reduce the irritation of the nozzle 3 to the nasal cavity.
In a further embodiment of the utility model, the nozzle 3 is further provided with a detachable dust cap 5.
In still another embodiment of the present utility model, the liquid outlet pipe 1, the nozzle 3, and the dust cap 5 are made of polypropylene.
When the spray nozzle is used, the dust cap 5 is firstly taken down, and when the spray nozzle is used for the first time, the spray nozzle is pressed by the thumb, and the pressing is repeated until uniform spraying occurs. After being ready; the bottle body is held by hand, the thumb is placed on the spray head, the bottle body is kept vertical during spraying, one end of the nozzle of the nasal sprayer faces the face, the nozzle is slowly inserted into any nostril along the nasal septum until the nozzle limiting device 4 is touched, and the spray head is pressed downwards once by the thumb forcefully at the moment, so that spray administration is completed once. And (5) removing the nozzle, inserting the nozzle into the other nostril by the same action, and completing the administration of the other nostril.
It will be apparent to those skilled in the art that various modifications and variations can be made to the present utility model without departing from the spirit or scope of the utility model. Thus, it is intended that the present utility model also include such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.
Claims (12)
1. The nasal sprayer comprises a liquid outlet pipe (1), a water core (2) and a nozzle (3), wherein the water core (2) is arranged in the nozzle (3), and a liquid outlet is formed in one end of the nozzle (3); one end of the liquid outlet pipe (1) is connected with the nozzle (3), and the other end of the liquid outlet pipe (1) is connected with an external liquid medicine source, and the liquid outlet pipe is characterized in that the liquid outlet pipe (1) is arranged into a bent shape with a certain angle A.
2. Nasal spray for increasing the deposition rate of a medicinal product sniffing zone according to claim 1, characterized in that the angle a of the bend of the outlet pipe (1) is 90 ° to 180 °.
3. Nasal spray for increasing the deposition rate of a medicinal product sniffing zone according to claim 2, characterized in that the angle a of the bend of the outlet pipe (1) is 120 ° to 150 °.
4. A nasal spray for increasing the deposition rate of a medicinal product sniffing zone according to claim 3, characterized in that the angle a of the bend of the outlet tube (1) is selected from 125 °, 130 °, 135 °, 140 ° or 145 °.
5. Nasal spray for increasing the deposition rate of a medicinal product sniffing zone according to claim 1, characterized in that the end face of the outlet opening of the nozzle (3) is arranged in an arc shape.
6. Nasal sprayer for increasing the deposition rate of pharmaceutical products according to claim 5, characterized in that the other end of the nozzle (3) is provided with a limiting device (4).
7. The nasal sprayer for improving the deposition rate of the medicine olfactory region according to claim 6, wherein the distance between the liquid outlet of the nozzle (3) and the limiting device (4) is 20-30 mm.
8. The nasal sprayer for improving the deposition rate of the medicine olfactory region according to claim 7, wherein the distance between the liquid outlet of the nozzle (3) and the limiting device (4) is 22 mm-28 mm.
9. The nasal sprayer for improving the deposition rate of the medicine olfactory region according to claim 8, wherein the distance between the liquid outlet of the nozzle (3) and the limiting device (4) is 24-26 mm.
10. Nasal spray for increasing the deposition rate of a medicinal product sniffing zone according to claim 9, characterized in that the distance of the outlet opening of the nozzle (3) from the limiting device (4) is 25mm.
11. Nasal spray for increasing the deposition rate of pharmaceutical product according to any of the previous claims, characterized in that the nozzle (3) is further provided with a removable dust cap (5).
12. The nasal sprayer for improving the deposition rate of the medicine sniffing zone according to claim 11, wherein the liquid outlet pipe (1), the nozzle (3) and the dust cap (5) are made of polypropylene.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221815835.9U CN220676524U (en) | 2022-07-13 | 2022-07-13 | Nasal sprayer for improving deposition rate of medicine sniffing area |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221815835.9U CN220676524U (en) | 2022-07-13 | 2022-07-13 | Nasal sprayer for improving deposition rate of medicine sniffing area |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220676524U true CN220676524U (en) | 2024-03-29 |
Family
ID=90374428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221815835.9U Active CN220676524U (en) | 2022-07-13 | 2022-07-13 | Nasal sprayer for improving deposition rate of medicine sniffing area |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220676524U (en) |
-
2022
- 2022-07-13 CN CN202221815835.9U patent/CN220676524U/en active Active
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| GR01 | Patent grant | ||
| GR01 | Patent grant |