CN102125723B - Vestibular administration device for nasal cavity - Google Patents

Vestibular administration device for nasal cavity Download PDF

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Publication number
CN102125723B
CN102125723B CN 201110105084 CN201110105084A CN102125723B CN 102125723 B CN102125723 B CN 102125723B CN 201110105084 CN201110105084 CN 201110105084 CN 201110105084 A CN201110105084 A CN 201110105084A CN 102125723 B CN102125723 B CN 102125723B
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China
Prior art keywords
air bag
nasal cavity
dosing device
vestibule
powder
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Expired - Fee Related
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CN 201110105084
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CN102125723A (en
Inventor
大平永敏
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SHANGHAI BAITA MEDICAL PHARMACEUTICAL CO Ltd
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SHANGHAI BAITA MEDICAL PHARMACEUTICAL CO Ltd
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention discloses a vestibular administration device for a nasal cavity, which comprises an air bag and a catheter communicated with the air bag; the catheter is used for filling gas or liquid into the air bag; and an administration surface is arranged on the air bag. Compared with the conventional atomizing administration mode or cotton ball administration mode, the vestibular administration device has the advantages that: 1, the administration time is long, and the administration dose is accurate; 2, the administration device is prevented from being fallen off, is convenient to operate and does not influence aeration; 3, the application range is wide in clinical medical treatment; and 4, the vestibular administration device has a structure and low manufacturing cost, and is convenient to popularize and use.

Description

A kind of nasal cavity vestibule dosing device
Technical field
The present invention relates to a kind of medical apparatus and instruments, relate in particular to a kind of nasal cavity vestibule dosing device.
Background technology
Medication commonly used comprises that oral, drug administration by injection, skin attach, rectally clinically, nasal cavity administration etc.Oral administration, owing to being subject to the impact of gastric juice, the oral of some medicine is restricted, and some medicines also have the gastrointestinal side effect; Drug administration by injection is subject to the restriction of medical condition, and majority can only be carried out in medical institutions, and the stimulation that bears the pain in addition; The assimilation effect of percutaneous drug delivery is not desirable, and effect is slow; Rectally not only is subject to the factor affecting such as excremental, and owing to physiology and psychological reason, many patients should not accept; Nasal-cavity administration is most for spraying administering mode.
On physiological structure, there is the inner face lining vestibule of nose front portion with skin, vibrissa is arranged, rear lateral portion has mucosa to cover, the mucosa of vestibule of nose continues mutually with skin, be squamous epithelial cancer and columnar epithelial cell transition region in the nasal vestibule before the nasal membrane, be also referred to as the nose threshold, the mucosa of the anterior nasal vestibule of nasal cavity continues mutually with skin.
Blood capillary on the nasal membrane is abundant, and this makes nasal membrane basic identical to infiltration rate and the intravenous injection of medicine, and the advantage of nasal-cavity administration is painless, absorbs fast, convenient, simple.Present nasal-cavity administration has atomizing, injecting type, and drip mainly is the cavum nasi proprium position administration behind vestibule of nose.These administering modes, medicine time of staying on mucosa is short, easily runs off to bottleneck throat, causes drug effect not good, and the drug dose inaccuracy affects nasal membrane to drug absorption and affects effect of drugs, particularly analgesics, the perhaps dispensing of insulin; The cotton balls administering mode, the dosage inaccuracy, mucosa can only absorb the medicine on cotton balls surface, is penetrated into the medicine of cotton balls middle body, is difficult to absorb, but also can be subject to the endocrine impact of nasal cavity.At present in the urgent need to a kind of fixed nasal cavity doser.
Summary of the invention
Technical problem to be solved by this invention provides a kind of nasal cavity vestibule dosing device, can be fixed on nasal cavity and control exactly nasal administration dosage.
In order to achieve the above object, the present invention proposes described nasal cavity vestibule dosing device, comprise an air bag and a conduit that is communicated with described air bag, described conduit is used for filling gas or liquid to described air bag, is provided with one on the described air bag to powder; Can make during described airbag inflation scribble medicine be close to the nasal vestibule mucomembranous surface to powder; Described nasal cavity vestibule dosing device comprises that also one is used for the center tube of ventilation, and described center tube runs through described air bag; Described air bag is outer convenient to be put into nasal cavity with described doser or takes out from nasal cavity thereby described center tube one end stretches out; Described give powder be shaped as circle or ellipse, central rounded vacancy; Described circular vacancy is used for accommodating center tube; Described air bag is hemisphere or semiellipsoid, and described conduit is connected in the land portions of described hemisphere or semiellipsoid air bag, is provided with a valve on the described conduit.
In the above-mentioned nasal cavity vestibule dosing device, preferably, described center tube comprises first terminal and the second end, and the end face of described the first end gives powder concordant with described air bag, described the second end stretches out outside the described air bag, and described air bag is fixedly connected with the first end of described center tube.
In the above-mentioned nasal cavity vestibule dosing device, preferably, described nasal cavity vestibule dosing device comprises that also one removably is connected in described air bag to the medicine film of powder, and the shape of giving powder of the shape of described medicine film and described air bag is complementary.
In the above-mentioned nasal cavity vestibule dosing device, preferably, described medicine film is made by cotton, polyethylene or fibers material, and described medicine film is attached with viscose glue with the one side that described air bag is connected.
With respect to existing atomizing administration or cotton balls administering mode, nasal cavity vestibule dosing device of the present invention has the following advantages:
1. administration time is long, and dosage is accurate;
2. avoid coming off, easy to operate, do not affect ventilation;
3. in the clinical treatment, the scope of application is wide: by the doser of nasal membrane, can carry out pain therapy, special cancer of late stage pain therapy can also carry out the insulinize of diabetics hyperglycemia control, also can be used for the drug treatment of other diseases;
4. simple in structure, cost of manufacture is cheap, is convenient to promote the use of.
Description of drawings
By the description of its exemplary embodiment being carried out below in conjunction with accompanying drawing, the above-mentioned feature and advantage of the present invention will become apparent and easily understand.
Fig. 1 is the structural representation of nasal cavity vestibule dosing device of the present invention;
Fig. 2 is center tube schematic diagram of the present invention;
Fig. 3 is medicine film schematic diagram of the present invention.
The reference numeral explanation:
The 2-center tube, 4-air bag, 5-conduit, 6-valve, 7-medicine film.
The specific embodiment
Below in conjunction with accompanying drawing the present invention is described in further detail.
Please refer to Fig. 1, Fig. 1 is the structural representation of nasal cavity vestibule dosing device of the present invention.Nasal cavity vestibule dosing device comprises air bag 4 and the conduit 5 that is communicated with air bag 4, and conduit 5 is used for filling gas or liquid to air bag 4.Be provided with a valve 6 on the conduit 5, valve 6 is a kind of valves.Conduit 5 can be made by silica gel or plastics.
Further, nasal cavity vestibule dosing device comprises that also one is used for the center tube 2 of ventilation, and center tube 2 runs through air bag 4.Center tube 2 comprises first terminal and the second end, and wherein the end face of the first end and air bag 4 is concordant to powder, and the second end stretches out outside the air bag 4, and air bag 4 is fixedly connected with the first end of center tube 2.Center tube 2 is used for nasal airflow, and one end (i.e. the second end) stretches out the air bag 4 outer operations that can conveniently this device be put into nasal cavity or take out from nasal cavity.This center tube 2 can be by silica gel, vinyon or wood, bamboo work.
Air bag 4 is hemisphere, can be by natural gum, and silica gel or fibers material are made, and have one to powder.Should circle or ellipse be arranged, central rounded vacancy to the shape of powder.This circle vacancy is used for accommodating center tube 2.Conduit 5 is connected in the land portions of hemisphere or semiellipsoid air bag 4.
Further, nasal cavity vestibule dosing device comprises that also one removably is connected in the air bag 4 medicine films 7 to powder, and the shape of giving powder of the shape of medicine film 7 and air bag 4 is complementary.Please refer to Fig. 3, Fig. 3 is medicine film schematic diagram of the present invention.When air bag 4 be when annular to powder, medicine film 7 also be annular.Medicine film 7 can be made by cotton, polyethylene or fibers material, has the sexual function of extension and water absorption function.Can cover drug powder on the medicine film 7, also can the permeation liquid medicine.Medicine film 7 has medical viscose to adhere to air bag 4 contact surfaces, can be attached on the air bag 4; After the use, but the medicine film 7 on strip off air bag 4 surfaces, and flusher sticks new medicine film 7 again during next administration, install namely repeatedly Reusability.
The using method of nasal cavity vestibule dosing device of the present invention is as follows:
Step 1, by entrance injecting gas or the liquid of syringe from conduit 5, air bag 4 expands under the pressure-acting of the gas that injects or liquid.After air bag 4 complete expansions, the valve 6 on the closure catheter for closing 5;
Step 2 is smeared medical viscose glue with the one side of medicine film 7, and the one side that this medicine film 7 scribbles medical viscose glue is sticked on the upper powder of air bag 4, coats the needed medicine for the treatment of at the another side of medicine film 7 immediately.
Step 3 is unclamped valve 6, and gas or liquid in the air bag 4 are emitted by conduit 5, air bag 4 is narrowed down to can put into nasal cavity;
Step 4: nasal cavity vestibule dosing device is put into nasal cavity, make it touch the nose threshold, re-inject gas or liquid by the entrance of conduit 5, air bag 4 reexpands and makes the medicine film 7 that scribbles medicine be close to the nasal vestibule mucomembranous surface, the valve 6 of closure catheter for closing 5;
Step 5 after the use, has conduit 5 to emit gas or liquid in the air bag 4, and nasal cavity vestibule dosing device is taken out from nasal cavity.
In above-mentioned steps four, preferably inject warm water, purpose is the vasodilation that is conducive to mucosa, blood flow increases to promote the abundant absorption of medicine.
The air bag 4 that expands can be fixed in the vestibule of nose, avoids coming off of device.Air bag 4 central authorities leave center tube 2, do not affect patient's ventilation.After the use, medicine film 7 can remove, and flusher changes new medicine film 7 into and covers air bag 4 surface continuation uses.Nasal cavity vestibule dosing device of the present invention is a kind of doser of simple in structure, easy to carry, non-invasive, can be used in the treatment of nose diseases, the dispensing treatment of general disease and cancer patient's analgesia therapy.
Studies show that clinically, the availability of interanasal administration can be near intravenous level, apparently higher than the availability of oral drugs; Can cardiovascular drug be arranged through the medicine that the intranasal method comes into operation, antipyretic analgesic, steroid hormone medicine, micromolecule and macromole polypeptide class medicine, antibiotic, antidiuretic and immune formulation etc.Interanasal administration has avoided the medicine gastrointestinal to stimulate the regulating liver-QI gastrointestinal tract to the metabolism of medicine first passage, and nasal mucosa is very little to the metabolism of medicine, can improve the bioavailability of medicine.
It should be noted that; above content is in conjunction with concrete embodiment further description made for the present invention; can not assert that the specific embodiment of the present invention only limits to this; under above-mentioned guidance of the present invention; those skilled in the art can carry out various improvement and distortion on the basis of above-described embodiment, and these improvement or distortion drop in protection scope of the present invention.

Claims (4)

1. nasal cavity vestibule dosing device is characterized in that:
Described nasal cavity vestibule dosing device comprises an air bag and a conduit that is communicated with described air bag, and described conduit is used for filling gas or liquid to described air bag, is provided with one on the described air bag to powder; Can make during described airbag inflation scribble medicine be close to the nasal vestibule mucomembranous surface to powder;
Described nasal cavity vestibule dosing device comprises that also one is used for the center tube of ventilation, and described center tube runs through described air bag; Described air bag is outer convenient to be put into nasal cavity with described doser or takes out from nasal cavity thereby described center tube one end stretches out;
Described give powder be shaped as circle or ellipse, central rounded vacancy; Described circular vacancy is used for accommodating center tube;
Described air bag is hemisphere or semiellipsoid, and described conduit is connected in the land portions of described hemisphere or semiellipsoid air bag, is provided with a valve on the described conduit.
2. nasal cavity vestibule dosing device according to claim 1 is characterized in that:
Described center tube comprises first terminal and the second end, and the end face of described the first end gives powder concordant with described air bag, and described the second end stretches out outside the described air bag, and described air bag is fixedly connected with the first end of described center tube.
3. nasal cavity vestibule dosing device according to claim 1 and 2 is characterized in that:
Described nasal cavity vestibule dosing device comprises that also one removably is connected in described air bag to the medicine film of powder, and the shape of giving powder of the shape of described medicine film and described air bag is complementary.
4. nasal cavity vestibule dosing device according to claim 3 is characterized in that:
Described medicine film is made by cotton, polyethylene or fibers material, and described medicine film is attached with viscose glue with the one side that described air bag is connected.
CN 201110105084 2011-04-26 2011-04-26 Vestibular administration device for nasal cavity Expired - Fee Related CN102125723B (en)

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CN 201110105084 CN102125723B (en) 2011-04-26 2011-04-26 Vestibular administration device for nasal cavity

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Application Number Priority Date Filing Date Title
CN 201110105084 CN102125723B (en) 2011-04-26 2011-04-26 Vestibular administration device for nasal cavity

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CN102125723B true CN102125723B (en) 2013-01-23

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929925B (en) * 2017-12-13 2020-06-09 杨兆辉 Breathe special medicine feeding device of internal medicine
CN111759720B (en) * 2020-07-07 2022-08-02 上海长海医院 Disposable nasal cleaning drug delivery device

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85200105U (en) * 1985-04-01 1985-09-10 59170部队附属医院 First-aid hemostal with breathing tube for epistaxis
CN2041941U (en) * 1988-05-27 1989-08-02 吉小红 Health care device of nasal mucosa
CN2650780Y (en) * 2003-09-19 2004-10-27 周广刚 Nasopharynx protector
CN201537113U (en) * 2009-12-04 2010-08-04 王昭清 Self-retaining nasal balloon
CN201542680U (en) * 2009-12-16 2010-08-11 谭秀岭 Nasal hemostasis device
CN202061229U (en) * 2011-04-26 2011-12-07 上海白塔医药科技有限公司 Nasal cavity vestibule dosing device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85200105U (en) * 1985-04-01 1985-09-10 59170部队附属医院 First-aid hemostal with breathing tube for epistaxis
CN2041941U (en) * 1988-05-27 1989-08-02 吉小红 Health care device of nasal mucosa
CN2650780Y (en) * 2003-09-19 2004-10-27 周广刚 Nasopharynx protector
CN201537113U (en) * 2009-12-04 2010-08-04 王昭清 Self-retaining nasal balloon
CN201542680U (en) * 2009-12-16 2010-08-11 谭秀岭 Nasal hemostasis device
CN202061229U (en) * 2011-04-26 2011-12-07 上海白塔医药科技有限公司 Nasal cavity vestibule dosing device

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