CN115068795A - Spray head for spraying liquid medicine into nose and device thereof - Google Patents

Spray head for spraying liquid medicine into nose and device thereof Download PDF

Info

Publication number
CN115068795A
CN115068795A CN202210894745.1A CN202210894745A CN115068795A CN 115068795 A CN115068795 A CN 115068795A CN 202210894745 A CN202210894745 A CN 202210894745A CN 115068795 A CN115068795 A CN 115068795A
Authority
CN
China
Prior art keywords
flow channel
spray head
liquid medicine
water
spraying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210894745.1A
Other languages
Chinese (zh)
Inventor
刘静怡
陈柱佗
李春成
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nasofide Shanghai Pharmaceutical Technology Co ltd
Original Assignee
Nasofide Shanghai Pharmaceutical Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nasofide Shanghai Pharmaceutical Technology Co ltd filed Critical Nasofide Shanghai Pharmaceutical Technology Co ltd
Priority to CN202210894745.1A priority Critical patent/CN115068795A/en
Publication of CN115068795A publication Critical patent/CN115068795A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0618Nose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention relates to the technical field of medical equipment, and provides a spray head for spraying liquid medicine into the nose and a device thereof, wherein the spray head comprises: the nozzle is provided with a flow channel which penetrates along the axial direction, and the far end and the near end of the flow channel are respectively a flow channel outlet and a flow channel inlet; the water core is circumferentially provided with a water passing groove and is configured inside the flow channel; the liquid outlet pipe is bent and comprises a parallel section and an inclined section which are integrally connected. The tail end of the inclined section extends to the inside of the flow channel from the flow channel inlet and is in sealing fit with the inner wall of the flow channel in the circumferential direction, so that when fluid flows in from the parallel section, the fluid flows out from the inclined section, enters the inside of the flow channel and is sprayed out from the flow channel outlet after passing through the water channel.

Description

Spray head for spraying liquid medicine into nose and device thereof
Technical Field
The invention relates to the technical field of medical equipment, in particular to a spray head for spraying liquid medicine into the nose and a device thereof.
Background
The Blood Brain Barrier (BBB) is the most important bottleneck for drugs to play a role in central disease therapy, and existing routes of administration such as oral, intravenous, intramuscular, subcutaneous, etc. cannot effectively deliver drugs to the Central Nervous System (CNS) due to the presence of the blood brain barrier. The drugs cannot effectively cross the blood brain barrier, and thus cannot play a role in treating brain diseases. In addition, as the dosage of the drug increases, systemic side effects also increase.
The central administration route comprises methods such as lateral ventricle administration (ICV) and direct injection of brain parenchyma, and although the central administration route has good targeting property and can directly deliver the medicament to the injured brain area to play a curative effect, complications such as infection and the like may occur after operation because of the traumatic property of the cranium operation. In addition, the existing central administration route has high cost and heavy economic burden on patients, and the wide application of the existing central administration route is not practical for thousands of encephalopathy patients. Therefore, the key point of the medicine for playing the actual treatment role of the brain diseases is to find a non-invasive central administration route which avoids the obstruction of the blood brain barrier.
The administration through the nasal mucosa has been regarded as the mode of the administration that a medicine can be absorbed by high efficiency fast, has a lot of fine villi on the nasal mucosa cell, can greatly increased the absorptive effective area of medicine, has abundant blood vessel and lymphatic vessel under the mucosa cell, and the medicine can directly get into the systemic circulation after through mucosa absorption, and in addition, the metabolism of enzyme is less than the intestines and stomach far away in the nasal cavity, and consequently, nasal cavity delivery system is receiving people's attention increasingly.
The nasal spray device in the prior art can not be accurately positioned to the olfactory region, so that the brain targeting property is reduced. The conventional nasal spray mainly deposits in the lower nasal passage, and the medicine firstly enters blood after being absorbed by the transmembrane and then enters the brain after crossing the blood brain barrier. However, the olfactory region is rich in olfactory nerves, so that the drugs can bypass BBB and enter the brain directly. In addition, since the drug solution is directly administered into the brain, accuracy and parallelism of administration are particularly important.
Under the non-upright condition, the handheld sprayer of patient uses difference at every turn easily, and it is poor to lead to the parallelism of liquid medicine nasal cavity deposition position, probably influences the drug effect, and the patient is when being treated by oneself at home, is difficult to the accuracy to holding in the nose part, how to guarantee that the liquid medicine sprays to smelling the key that the district becomes the treatment with the best angle, consequently need design a section have highly smell district target good, the precision of dosing is high, the parallelism is good, use and convenient to carry's equipment to solve prior art's not enough.
Disclosure of Invention
In view of the shortcomings of the prior art, it is an object of the present invention to provide a spray head for spraying liquid medicine intranasally and a device thereof.
According to the present invention, there is provided a spray head for spraying a liquid medicine intranasally, comprising:
the nozzle is provided with a flow channel which penetrates through the nozzle along the axial direction, and the far end and the near end of the flow channel are respectively communicated with the outside through a flow channel outlet and a flow channel inlet;
the water core is circumferentially provided with a water passing groove and is arranged inside the flow channel and close to the far end of the flow channel;
the drain pipe is the bending type, including a body coupling's parallel section and slope section, wherein, the end of slope section is followed the runner import extends to the inside and circumference of runner with the sealed laminating of inner wall of runner makes when fluid from the parallel section flow in from the slope section outflow entering the runner is inside and follow behind the basin the spout of runner export.
Preferably, the proximal end of the nozzle is provided with a stop so that the stop can locate the distal end of the flow passage when it reaches the deepest point inside the nostril.
Preferably, the water passing groove extends in the axial direction of the water core.
Preferably, the water core comprises a water core front end and a water core rear end, and the water passing trough is arranged at the water core rear end;
the outer diameter of the rear end of the water core is larger than that of the front end of the water core.
Preferably, the end part of the front end of the water core is a circular plane, and one side of the flow passage outlet facing the front end of the water core is provided with a cyclone groove.
Preferably, the position of the flow channel for accommodating the front end of the water core is a stepped structure with gradually reduced space towards the far end.
Preferably, the end part of the rear end of the water core is concave, and the concave part is communicated with the water passing groove.
Preferably, the outer part of the far end of the flow passage is of a concave bowl bottom concave structure.
Preferably, the connection mode of the nozzle and the rear end of the water core is interference fit, clamping connection or threaded connection.
According to the invention, the device for spraying the liquid medicine to the nose comprises the spray head for spraying the liquid medicine to the nose, and further comprises:
the top of the spray head is connected with the parallel section and is used for conveying fluid;
the top of the quantitative pump is connected with the bottom of the spray head and provides power for fluid conveying;
the stock solution bottle for hold fluid, the dosing pump match install on the stock solution bottle and the bottom extend to the inside bottommost of stock solution bottle.
Compared with the prior art, the invention has the following beneficial effects:
1. the liquid outlet pipe is arranged in a bent shape, so that the medicine source part of the nasal sprayer can be kept upright, and the liquid medicine is sprayed to the olfactory region at the optimal angle under the guiding action of the plurality of water passing grooves circumferentially arranged on the water core, so that the problem of poor parallelism of the deposition position of the nasal cavity of the liquid medicine is solved, the deposition rate of the olfactory region is increased, the brain targeting property of the medicine is improved, and the potential side effect of a peripheral system is reduced.
2. The end part of the front end of the water core is a circular plane, the side of the channel outlet facing the front end of the water core is provided with the cyclone groove and the spray hole to form a coherent structure, and compared with the structure that the cyclone groove is arranged on the water core and is separated from the spray hole in the prior art, the cyclone groove avoids the effect of weakening the impact between cyclone fluid and the wall surface of the spray hole, so that the fluid rotation and the spray hole spraying are finished at one time, and the spraying effect is better.
3. The design of the nozzle limiting structure can overcome the defect that the length of the nasal part of a patient is difficult to accurately control when the patient self-administers the medicine, so that the medicine effect is reduced.
4. The water core is arranged into a plurality of water passing grooves, the total water passing amount of the water passing grooves is less than the water passing space formed by the front end of the water core and the nozzle, the explosion force of the spraying is moderate, the spraying can be centralized in an olfactory region, and all connecting parts can be kept to be tightly connected without being separated during spraying.
5. The invention can improve the deposition rate of the medicine in the olfactory region and improve the treatment efficiency of the medicine on nervous system diseases; improves the targeting property, the administration precision, the parallelism and the patient compliance of the medicament to the olfactory region, and has convenient use and carrying.
Drawings
Other features, objects and advantages of the invention will become more apparent upon reading of the detailed description of non-limiting embodiments with reference to the following drawings:
FIG. 1 is a schematic sectional view of the structure of a spray head according to the present invention;
FIG. 2 is a schematic sectional view of the assembled water core and nozzle of the present invention;
FIG. 3 is a schematic view of the present invention with the water core separated from the nozzle;
FIG. 4 is a schematic view showing the structure of a device for spraying a liquid medicine intranasally according to the present invention;
FIG. 5 is a schematic sectional view showing the structure of a device for spraying a liquid medicine intranasally according to the present invention;
FIG. 6 is an exploded view of the structure of the device for spraying a liquid medicine into the nose of the present invention;
FIG. 7 is a schematic structural view of a cross section of a cyclone groove.
The figures show that:
liquid outlet pipe 1
Parallel section 11
The inclined section 12
Water core 2
Front end 21 of water core
Rear end 22 of water core
Water passing groove 221
Nozzle 3
Flow passage 31
Flow channel outlet 311
Flow channel inlet 312
Limiting structure 32
Spray head 4
Dust cap 5
Constant delivery pump 6
A liquid storage bottle 7.
Detailed Description
The present invention will be described in detail with reference to specific examples. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that it would be obvious to those skilled in the art that various changes and modifications can be made without departing from the spirit of the invention. All falling within the scope of the present invention.
Example 1:
the invention provides a spray head for spraying liquid medicine to the nose, which comprises a liquid outlet pipe 1, a water core 2 and a nozzle 3, wherein as shown in figures 1, 2 and 3, the nozzle 3 is provided with a flow channel 31 which penetrates through along the axial direction, and the far end and the near end of the flow channel 31 are respectively communicated with the outside through a flow channel outlet 311 and a flow channel inlet 312; the water core 2 is circumferentially provided with water passing grooves 221, the water passing grooves 221 preferably extend in the axial direction of the water core 2, the number of the water passing grooves 221 can be set to be one, or a plurality of water passing grooves 221 can be uniformly or non-uniformly arranged in the circumferential direction of the water core 2, and the water passing grooves 221 are arranged inside the flow channel 31 and close to the far end of the flow channel 31; the liquid outlet pipe 1 is bent, the special bending degree of the liquid outlet pipe 1 can enhance the use compliance of a patient, the device can be conveniently pressed vertically when liquid medicine is sprayed, and the liquid medicine is more favorably sprayed; and the patient is when using at home, the spacing function of nozzle 3 can ensure the parallelism of dosing, accurate location and high targeting are to smelling the district injection, improve smelling of liquid medicine and distinguish the sedimentation rate, drain pipe 1 is including parallel section 11 and the slope section 12 of an organic whole connection, parallel section 11 and slope section 12 are certain contained angle, the sealed laminating of the inner wall of the inside and circumference that runner 31 extends to runner 31 from runner import 312 of the end of slope section 12 and runner 31 makes when the fluid flows in from parallel section 11 and flows out from slope section 12 and get into inside runner 31 and spout from runner export 311 behind basin 221.
It should be noted that after the nozzle 3 is connected to the front end 21 of the water core, a sealed cavity is formed inside the nozzle 3, and the connection mode between the nozzle 3 and the rear end 22 of the water core may be interference fit, snap fit or threaded connection, preferably interference fit.
Specifically, the proximal end of the nozzle 3 is provided with the limiting structure 32, so that the position of the distal end of the flow passage 31 extending into the deepest position inside the nostril can be positioned by the limiting structure 32, therefore, when the patient uses the device, the distal end of the nozzle 3 can conveniently and easily reach the position which is most suitable for spraying inside the nostril through the limiting structure 32, and the convenience and the accuracy of operation are greatly improved.
Further, the water core 2 comprises a water core front end 21 and a water core rear end 22, the water passing groove 221 is arranged at the water core rear end 22, the outer diameter of the water core rear end 22 is preferably larger than that of the water core front end 21, and the total water passing amount of the water passing space formed by the radial distance between the water core rear end 22 and the nozzle 3 is smaller than that of the water passing groove 221.
In practical application, the position of the flow channel 31 for accommodating the front end 21 of the water core is a stepped structure with a gradually reduced space towards the far end, the end part of the rear end 22 of the water core is concave and the concave part is communicated with the water passing groove 221, when fluid flows to the position, the fluid enters the concave part and then enters the water passing groove 221, a certain uniform flow dividing effect is achieved, the end part of the front end 21 of the water core is a circular plane, the side of the flow channel outlet 311 facing the front end 21 of the water core is provided with a cyclone groove, and when the fluid flows to the cyclone groove, a swirl chamber of a swirl orifice is formed and is finally presented by the formation of spray.
As shown in fig. 2, the outer portion of the distal end of the flow channel 31 is a concave bowl bottom structure, and the small aperture of the flow channel outlet 311 and the concave bowl bottom structure make the ejected fluid in a divergent shape and ejected in a conical mist shape.
The invention also provides a device for spraying the liquid medicine into the nose, which comprises a spray head for spraying the liquid medicine into the nose, as shown in fig. 4 and 5, and further comprises a spray head 4, a quantitative pump 6 and a liquid storage bottle 7, wherein the top of the spray head 4 is connected with a parallel section 11 for conveying fluid; the top of the fixed displacement pump 6 is connected with the bottom of the spray head 4 to provide power for fluid delivery; the liquid storage bottle 7 is used for containing fluid, the dosing pump 6 is installed on the liquid storage bottle 7 in a matched mode, the bottom end of the dosing pump 6 extends to the lowest end inside the liquid storage bottle 7, the fluid in the liquid storage bottle is liquid medicine, the liquid medicine is sealed in the liquid storage bottle 7, the end portion of the parallel section 11 of the liquid outlet pipe 1 is connected with the branch pipe of the dosing pump 6, and the liquid storage bottle 7 can be selected from a press buckle bottle, a threaded bottle and the like.
It should be noted that the dosing pump 6 of the present invention is a conventional pump, and will not be described herein.
Example 2:
this embodiment is a preferred embodiment of embodiment 1.
The embodiment provides a device for spraying liquid medicine into nose, as shown in fig. 6, comprising a liquid outlet pipe 1, a water core 2 and a nozzle 3, wherein the liquid outlet pipe 1 is arranged in a bent shape with a certain angle, a parallel section 11 is connected with an external medicine source, an inclined section 12 is connected with the nozzle 3, a liquid outlet end of the nozzle 3 is provided with a spray hole, namely a flow channel outlet 311, and a front end 21 of the water core 2 is matched with the spray hole of the nozzle 3 to form a spray hole vortex chamber; the water core rear end 22 of the nozzle 3 is provided with a limiting structure 32, the limiting structure 32 and the nozzle 3 are integrally formed, the limiting structure 32 in the embodiment is a circular ring structure, and when the structure is specifically designed, the structure can be designed into other structures, such as a sector ring shape, and further designed into a plurality of discontinuous sector ring structures, and the like, so that the structure can be flexibly designed according to the beautiful and practical requirements of the appearance, and the description is omitted here.
The water core 2 is a solid irregular cylinder, the water core 2 is integrally formed, and one or more water passing grooves 221 are formed in the rear end 22 of the water core; the front end 21 of the water core is connected with the nozzle 3, and the axial positions of the liquid outlet pipe 1, the water core 2 and the nozzle 3 are fixed.
It should be noted that, the special camber of drain pipe 1 can guarantee that the liquid medicine sprays to smelling the district with the best angle, and the patient can not appear when treating by oneself at home the situation that is difficult to accurate assurance to the nasal part of going into, and precision and parallelism are limit structure 32 and the comprehensive effect of angle. The advantages of the invention include high olfactory region targeting, administration accuracy, parallelism, patient compliance, and convenience in use and carrying.
In this embodiment, the water passing groove 221 is disposed along the axial direction of the water core 2, and the water passing groove 221 may be rectangular, circular, triangular, or the like.
In this embodiment, the difference between the inner radius of the nozzle 3 and the radius of the water core front end 21 is 0.2 mm; the nozzle 3 is connected with the liquid outlet pipe 1 in an interference manner.
In this embodiment, the bending angle of the liquid outlet pipe 1, that is, the included angle between the parallel section 11 and the inclined section 12, is greater than 90 degrees and smaller than 180 degrees; more preferably, it is 120 ° to 150 °, for example, 125 °, 130 °, 135 °, 140 °, 145 °, or the like.
In this embodiment, the diameter of the stop 32 is greater than the diameter of the nostril.
In this embodiment, the distance from the flow channel outlet 311 of the nozzle 3 to the limiting structure 32 is 20mm to 30mm, more preferably 22mm to 28mm, and still more preferably 24mm to 26 mm; most preferably 25mm, to reach as deep as possible into the nasal cavity within the acceptable comfort range of the patient to match the spray effect and improve the drug deposition rate in the olfactory region.
In this embodiment, the end surface of the flow passage outlet 311 of the nozzle 3 is set to be a curved surface to reduce the irritation of the nozzle 3 to the nasal cavity.
In this embodiment, the nozzle 3 is further provided with a detachable dust cap 5 to prevent adhesion of dust to the flow path outlet 311 and irritation of the nasal cavity.
In this embodiment, the liquid outlet pipe 1, the nozzle 3, and the dust cap 5 are preferably made of polypropylene or polyethylene, and in practical applications, the liquid outlet pipe 1, the nozzle 3, and the dust cap 5 may be made of other materials to satisfy the storage of the medicine and facilitate the spraying of the liquid medicine.
The operation principle of the invention for spraying the liquid medicine into the nose is as follows:
when the sprayer is used, the dust cover 5 is firstly taken down, and when the sprayer is used for the first time, the sprayer 4 is pressed by fingers, and the pressing is repeated for X times until uniform spraying appears. Hold liquid storage bottle 7 bottle, the thumb is put on shower nozzle 4, keeps the bottle perpendicular during spraying, with the runner export 311 of nasal spray ware nozzle 3 towards the face to slowly insert any one nostril along the septum of nose with nozzle 3, until touch nozzle limit structure 32, press shower nozzle 4 downwards hard once with the thumb this moment, accomplish a spraying and administer medicine. Specifically, the medicine spraying can be repeated after a certain time interval, or the nozzle 3 can be removed and inserted into the other nostril by the same action, so that the medicine feeding of the other nostril is completed.
The working principle of the fluid flow process and the final spray formation in the invention is as follows:
the end face of the front end 21 of the water core is a circular plane, the back of the flow passage outlet 311 of the nose sprayer nozzle 3 is provided with a cyclone groove, the circular plane is matched with the plane of the cyclone groove to form a spray hole vortex chamber, the water passing groove 221 of the rear end 22 of the water core and the space formed between the front end 21 of the water core and the nose sprayer nozzle 3 form a liquid spraying channel together, the liquid flows to the rear end 22 of the water core and reaches the spray hole vortex chamber through the spraying channel, and when passing through the spray hole vortex chamber, the liquid forms a plurality of liquid flows through the channel of the cyclone groove to collide at the spray hole to form a fog shape, namely form tiny particles, thereby forming the spraying effect.
In order to realize the technical effect that the liquid medicine is directly injected into the nasal cavity and the olfactory region, firstly, the depth of the liquid medicine entering the nose is controlled, the distance from the spray hole of the nozzle 3 to the limiting structure 32 is preferably designed to be 25mm, and the liquid medicine can be accurately positioned to the olfactory region; secondly, the liquid outlet pipe 1 is set to be the most suitable liquid spraying angle, so that the liquid storage bottle is favorable for keeping upright, the spraying operation is favorable, and the liquid medicine is more favorable for being delivered to a smelling area; finally, the design is in an atomization mode, a cyclone groove is arranged on a flow passage outlet 311 of the nozzle 3 and is matched with the water core 2 to form a vortex chamber, and the liquid medicine is directly injected to an olfactory region through a spray hole.
In the description of the present application, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience in describing the present application and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present application.
The foregoing description of specific embodiments of the present invention has been presented. It is to be understood that the present invention is not limited to the specific embodiments described above, and that various changes or modifications may be made by one skilled in the art within the scope of the appended claims without departing from the spirit of the invention. The embodiments and features of the embodiments of the present application may be combined with each other arbitrarily without conflict.

Claims (10)

1. A spray head for spraying a liquid medicine intranasally, comprising:
a nozzle (3) which is provided with a flow channel (31) penetrating along the axial direction, wherein the far end and the near end of the flow channel (31) are respectively communicated with the outside through a flow channel outlet (311) and a flow channel inlet (312);
the water core (2) is circumferentially provided with a water passing groove (221) and is configured inside the flow channel (31) and close to the far end of the flow channel (31), the water passing groove (221) is arranged at the rear end (22) of the water core, the end part of the rear end (22) of the water core is concave, the concave part is communicated with the water passing groove (221), the end part of the front end (21) of the water core is a circular plane, and one side of the flow channel outlet (311) facing the front end (21) of the water core is provided with a cyclone groove;
drain pipe (1), be the bending type, parallel section (11) and slope section (12) including an organic whole connection, wherein, the end of slope section (12) is followed runner import (312) extend to the inside and circumference of runner (31) with the sealed laminating of inner wall of runner (31) makes when fluid from parallel section (11) inflow from slope section (12) outflow entering inside and through basin (221) back follow runner export (311) blowout.
2. A spray head for the intranasal administration of liquid medicine according to claim 1, characterized in that the proximal end of the nozzle (3) is provided with a stopper structure (32) so that the position where the distal end of the flow path (31) extends to the deepest inside the nostril can be positioned by the stopper structure (32).
3. Spray head for intranasal spraying of liquid medicine according to claim 1, characterized in that the water passing groove (221) extends in the axial direction of the water core (2).
4. The spray head for spraying liquid medicine intranasally according to claim 1 wherein the outer diameter of the rear end (22) of the cartridge is larger than the outer diameter of the front end (21) of the cartridge.
5. A spray head for spraying a liquid medicine intranasally according to claim 1 wherein said flow passage (31) accommodates said front end (21) of said cartridge in a stepped configuration with a gradually decreasing space in a distal direction.
6. A spray head for the intranasal administration of liquid medicine according to claim 1, wherein the outer portion of the distal end of the flow passage (31) is of a concave bowl bottom structure.
7. A sprayhead for nasal spray of liquid medicine according to claim 1 wherein the nozzle (3) is attached to the rear end (22) of the cartridge by interference fit, snap fit or screw thread.
8. Spray head for the intranasal administration of liquid medicine according to claim 1, characterized in that the radial distance of the rear end (22) of the cartridge from the nozzle (3) forms a water passage space with a total water passage amount which is less than the total water passage amount of the water passage tank (221).
9. A spray head for spraying liquid medicine intranasally according to claim 1 wherein said water core (2) is uniformly arranged with a plurality of water passing grooves (221) in the circumferential direction.
10. A device for spraying a liquid medicine intranasally comprising the spray head for spraying a liquid medicine intranasally according to any one of claims 1 to 9, further comprising:
the top of the spray head (4) is connected with the parallel section (11) and is used for conveying fluid;
the top of the quantitative pump (6) is connected with the bottom of the spray head (4) to provide power for conveying the fluid;
the liquid storage bottle (7) is used for containing fluid, and the dosing pump (6) is installed in a matched mode on the liquid storage bottle (7) and the bottom end of the dosing pump extends to the bottom end inside the liquid storage bottle (7).
CN202210894745.1A 2022-07-28 2022-07-28 Spray head for spraying liquid medicine into nose and device thereof Pending CN115068795A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210894745.1A CN115068795A (en) 2022-07-28 2022-07-28 Spray head for spraying liquid medicine into nose and device thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210894745.1A CN115068795A (en) 2022-07-28 2022-07-28 Spray head for spraying liquid medicine into nose and device thereof

Publications (1)

Publication Number Publication Date
CN115068795A true CN115068795A (en) 2022-09-20

Family

ID=83242194

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210894745.1A Pending CN115068795A (en) 2022-07-28 2022-07-28 Spray head for spraying liquid medicine into nose and device thereof

Country Status (1)

Country Link
CN (1) CN115068795A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024021769A1 (en) * 2022-07-28 2024-02-01 Nasal-Phyto (Sz) Pharmaceutical Technology Co., Ltd. Spray head and device for intranasal spraying of liquid medicine

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201061658Y (en) * 2007-06-22 2008-05-21 程波 Disposal waxiness type quantitative oropharynx spray head
CN204446847U (en) * 2015-03-03 2015-07-08 苏州同力生物医药有限公司 A kind of disposable per nasal brain-targeted drug delivery device
CN206548948U (en) * 2016-08-09 2017-10-13 宁波正力药品包装有限公司 The nozzle that a kind of atomizing syringe is used
CN207654263U (en) * 2017-06-13 2018-07-27 刘文岐 Tooth nasal cavity closestool
CN208511699U (en) * 2018-02-27 2019-02-19 上海弼诺医疗器械有限公司 Nasal sprayer
CN214158254U (en) * 2020-06-19 2021-09-10 吴昌德 Rhinitis treatment device
CN113456949A (en) * 2021-06-16 2021-10-01 中山市联昌喷雾泵有限公司 Sprayer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201061658Y (en) * 2007-06-22 2008-05-21 程波 Disposal waxiness type quantitative oropharynx spray head
CN204446847U (en) * 2015-03-03 2015-07-08 苏州同力生物医药有限公司 A kind of disposable per nasal brain-targeted drug delivery device
CN206548948U (en) * 2016-08-09 2017-10-13 宁波正力药品包装有限公司 The nozzle that a kind of atomizing syringe is used
CN207654263U (en) * 2017-06-13 2018-07-27 刘文岐 Tooth nasal cavity closestool
CN208511699U (en) * 2018-02-27 2019-02-19 上海弼诺医疗器械有限公司 Nasal sprayer
CN214158254U (en) * 2020-06-19 2021-09-10 吴昌德 Rhinitis treatment device
CN113456949A (en) * 2021-06-16 2021-10-01 中山市联昌喷雾泵有限公司 Sprayer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024021769A1 (en) * 2022-07-28 2024-02-01 Nasal-Phyto (Sz) Pharmaceutical Technology Co., Ltd. Spray head and device for intranasal spraying of liquid medicine

Similar Documents

Publication Publication Date Title
CA3016781C (en) Atomizer for nasal therapy
KR100236431B1 (en) Nasal cavity medicator
US11975164B2 (en) Nasal drug delivery device and method of making same
US20140283820A1 (en) Method for Esophageal Drug Delivery
CN115068795A (en) Spray head for spraying liquid medicine into nose and device thereof
US9440020B2 (en) Nasal irrigator
US20160339188A1 (en) Portable Fluid Delivery System for the Nasal and Paranasal Sinus Cavities
JP2004537346A (en) Liquid spray device
CN106345044A (en) Cavity atomizing dosing device
US20210283384A1 (en) Dispenser
CN103977490A (en) Medical atomizer
CN219022752U (en) Spray head for spraying liquid medicine into nose and device thereof
RU2663493C2 (en) Device for delivery of an aerosol substance
CN219517430U (en) Device of accurate nose district injection
CN112472984B (en) Nasal cavity drug delivery device
CN219595498U (en) Spray head capable of guaranteeing administration parallelism of nasal and olfactory regions and device thereof
CN220424350U (en) Nose sprayer for targeting nasal meatus
CN220110254U (en) Device for delivering liquid medicine to nasal cavity
CN211068507U (en) Medical local atomizing medicine feeder
CN220676524U (en) Nasal sprayer for improving deposition rate of medicine sniffing area
CN203816006U (en) Medicament sprayer for use in respiratory medicine
CN219423551U (en) Disposable nasal cavity spraying drug delivery device
CN217525987U (en) Biological liquid medicine quantitative spraying bottle convenient to operate
CN215386924U (en) Nasal cavity medicine feeder
CN202223690U (en) Insulin sprayer

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination