CN219595498U - Spray head capable of guaranteeing administration parallelism of nasal and olfactory regions and device thereof - Google Patents

Abstract

The utility model relates to a medical instrument, in particular to a spray head capable of guaranteeing administration parallelism of a nasal and olfactory region and a device thereof. The inner wall of the top end of the spray head is provided with a cyclone groove, the center of the top end of the spray head is provided with a circular spray hole, the center of the cyclone groove is concentric with the spray hole, and the top end of the spray head is of a concave bowl bottom structure; the water core is integrally formed and provided with a water passing groove; the water outlet pipe is hollow; the administration reference plane bracket is used for ensuring the administration nose entrance angle and further ensuring the parallelism of the drug effect; the water outlet pipe, the water core, the cyclone groove and the spray holes sequentially form a communicated liquid medicine flow passage. Through setting up straight type liquid medicine acceleration channel, make the liquid medicine velocity of flow accelerate, form the divergent form fog liquid of specific angle after the whirlwind groove to combine the reference plane support of dosing, guaranteed the parallelism of dosing. The utility model has simple structure and low cost, and is suitable for industrial production.

Description

Spray head capable of guaranteeing administration parallelism of nasal and olfactory regions and device thereof

Technical Field

The present utility model relates to medical devices, and more particularly to a spray head for delivering a drug to the nasal olfactory region.

Background

With the continuous development of medical technology, nasal cavity sprayers have been popular for the public because of their low risk, rapid therapeutic effect, non-invasive treatment, etc., and they spray the liquid medicine into the nasal cavity for treating various diseases in the nasal cavity. Nasal administration is a mode of rapidly reaching the drug effect, and the main components of the drug can circulate the olfactory nerve (olfactory neural pathways) and the trigeminal nerve path (trigeminal neural pathway) distributed on the nasal mucosa, enter the nasal beak migration path (rostral migratory stream, RMS) to reach the olfactory bulb (angular bulb), enter the brain and the perivascular path (perivascular pathway) in the central nervous system, so that the main components of the drug can avoid blood-brain barrier (BBB) to reach the action part and brain of the central nerve. However, the conventional nasal cavity administration device has poor liquid dispersion effect in the administration process, large fogdrop particles, difficulty in sucking the medicine into the nasal cavity, difficulty in forming spray on the medicine liquid and influence the absorption of the medicine.

However, there are only two nasal delivery devices available for delivering drugs to the upper nasal passages, for multiple sprays, the first device is a nasal delivery device from the company impel, but the delivery device uses a method of adding a propellant to bring the drug to the upper nasal passages; another type is a nasal sprayer disclosed in fig. 4 of CN115068795a, which uses a hand pump or high air pressure to release the drug to make the drug enter the patient's upper nasal passages after forming an atomized state through an atomizer, and such a nasal sprayer is suitable for use in a multi-dose repeated administration scenario.

For certain first aid classes, narcotics and the like, a single spray use scenario can be used, and the advantages of the single spray nasal sprayer are that: the medicine liquid is extracted when in use, so that the medicine liquid can be stored for a long time; the device is thrown once after single use, so that the pollution problem of liquid medicine or the device is avoided.

At present, for the single spray delivery to the upper nasal meatus, only the single spray of an apr company is adopted, the method disclosed in CN 112512698A is adopted, after a piston is punctured by a steel needle, the piston is injected by a syringe for drug delivery, the method needs to use a steel needle structure, the method is not very convenient for use, and the deposition rate of the drug in a sniffing zone can only reach about 5-10%. Other types of single-dose nasal sprayers cannot deliver medicines to nasal olfactory regions, or have large medicine spraying pressure and high spraying speed in the administration process, so that discomfort is brought to patients, or the injector is adopted to provide thrust, and the medicine liquid is difficult to form spray to influence the absorption of the medicines due to insufficient spraying speed; or the fog drop particles are larger, and the spray scattering angle is large, so that the absorption effect of the medicine in the nasal cavity olfactory region is poor; more importantly, for different patients and different drug administration personnel, the drug administration angles of the sprayer are required to be consistent, and the parallelism of drug administration effects can be ensured; therefore, how to provide a nasal cavity administration spraying device with good atomization effect, high deposition rate in the olfactory region and good administration parallelism becomes a problem to be solved.

Disclosure of Invention

Therefore, the technical problem to be solved by the utility model is to overcome the defects that the drug delivery spraying device in the prior art is difficult to achieve a better atomization effect and difficult to ensure drug delivery parallelism, so as to provide a spraying head capable of ensuring drug delivery parallelism in a nasal-olfactory region and a device thereof.

In order to solve the technical problems, the utility model is realized by the following technical proposal,

a spray head for ensuring the parallelism of nasal and olfactory administration, comprising:

i) The spray head comprises a spray head top end and a spray head distal end, a cyclone groove is arranged on the inner wall of the spray head top end, a circular spray hole is arranged in the center of the spray head top end, the center of the cyclone groove is concentric with the spray hole, and the spray head top end is of a concave bowl bottom structure;

ii) a dosing reference plane support mounted and fixed on the distal sidewall of the spray head by interference or snap fit;

iii) The water core is integrally formed and is divided into a water core front end and a water core rear end, the diameter of the water core rear end is larger than that of the water core front end, one or more water passing grooves are formed in the water core rear end and are used for passing liquid medicine, the water passing grooves are concave, and the water core rear end is fixedly connected with the side wall of the spray head in an interference mode;

iv) a water outlet pipe, wherein the side wall of the water outlet pipe is fixedly connected with the side wall of the spray head in an interference manner, and the upper end of the water outlet pipe is connected with the lower end of the water core;

the water outlet pipe, the water core, the cyclone groove and the spray holes sequentially form a communicated liquid medicine flow passage.

Preferably, one end of the administration reference plane bracket is a U-shaped part, the U-shaped part is connected to the spray head in an interference or buckling mode, the other end of the administration reference plane bracket is a plane-shaped part, and a certain included angle is formed between the plane-shaped part and the central line of the spray head, preferably, the included angle is 50 degrees; the U-shaped portion and the planar portion are connected by a connecting mechanism, for example, the connecting mechanism may be linear or curved.

Preferably, the cyclone groove is provided with three rotary vanes which are uniformly distributed along the circumferential direction.

Preferably, the front end of the water core is in a uniform cylindrical shape, the end face of the front end of the water core is in a round shape, and the vortex chamber is formed with the cyclone groove.

Preferably, the water passing grooves extend in parallel along the water mandrel axis direction and are uniformly arranged along the circumferential direction.

Preferably, a limiting structure is further arranged on the outer side of the spray head, and the distance between the limiting structure and the spray hole is 2-3 cm, for example, 2.5cm.

The utility model also provides a device capable of ensuring the administration parallelism of the nasal and olfactory regions, which comprises the spray head and further comprises:

a means for providing a source of medication.

Preferably, the means for providing a source of medicament is a bolus assembly comprising a bolus tube, a push rod, the bolus assembly being removably disposed within the spray head.

Preferably, the device for spraying the liquid medicine to the nasal olfactory region is made of PP material.

Preferably, the head end of the push rod is also provided with a butyl rubber plug.

Preferably, the tail end of the push rod extends beyond the tail end of the injector cartridge.

Preferably, the diameter of the head end of the injector assembly is greater than the diameter of the outlet pipe.

Compared with the prior art, the utility model has the following beneficial effects:

the spray head and the device thereof provided by the utility model can ensure the administration parallelism of the nasal and olfactory regions, can carry out nasal cavity spray administration on liquid medicament, and have better spray effect than the prior art. The spray head enters the nose at a specific angle by arranging a specific administration reference plane bracket; the liquid medicine accelerating channel is arranged to accelerate the flow speed of the liquid medicine, and then the liquid medicine is rotated into a divergent fog liquid with a specific angle through the cyclone groove, so that the liquid medicine is concentrated in the nasal and olfactory region with a specific divergent angle, and the fog liquid medicine is easier to be absorbed by mucous membranes in the nasal and olfactory region. The utility model has simple structure and low cost, and is suitable for industrialized production.

Drawings

In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present utility model, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic view of a spray head device according to the present utility model;

FIG. 2 is a schematic structural view of a syringe assembly provided by the present utility model;

FIG. 3 is a schematic view of the device for spraying liquid medicine to the nasal olfactory region according to the present utility model;

fig. 4 is a schematic view of the structure of a pipette head assembly provided by the present utility model;

fig. 5 is a schematic structural view of a water core provided by the utility model.

Detailed Description

The assay methods of the present application will be described in further detail below with reference to specific examples. It is to be understood that the following examples are illustrative only and are not to be construed as limiting the scope of the utility model. All techniques implemented based on the above description of the utility model are intended to be included within the scope of the utility model.

In the description of the present patent application, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," "outer," and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, only for convenience in describing the present patent application and simplifying the description, and do not indicate or imply that the devices or elements being referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present patent application. Moreover, the terms "first," "second," "third," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In this application, unless specifically stated otherwise, the term "connected" includes both contacting and non-contacting connections, as determined by the actual use.

In one embodiment of the present utility model, there is provided a device for ensuring parallelism of administration in the nasal olfactory region, as shown in FIGS. 1-3, comprising: the spray head 1 and a device for providing a medicine source, wherein the spray head 1 comprises a spray head 11, the spray head 11 comprises a spray head top end and a spray head distal end, a cyclone groove is arranged on the inner wall of the spray head top end, the cyclone groove is provided with three rotary vanes which are uniformly distributed along the circumferential direction (not shown in the figure), a circular spray hole is arranged at the center of the spray head top end, the center of the cyclone groove is concentric with the spray hole, and the spray head top end is of a concave bowl-shaped bottom structure;

the administration reference plane bracket 5 is fixedly arranged on the side wall of the distal end of the spray head in an interference or snap fit mode; specifically, one end of the administration reference plane bracket 5 is a U-shaped part, the U-shaped part is connected to the spray head 11 by interference or fastening, the other end is a planar part, the planar part and the central line of the spray head have a certain included angle beta, and preferably, the included angle is 50 degrees; the U-shaped portion and the planar portion are connected by a connecting mechanism, for example, the connecting mechanism may be linear or curved.

The water core 13 is integrally formed and is divided into a water core front end 131 and a water core rear end 132, the diameter of the water core rear end is larger than that of the water core front end, one or more water passing grooves 133 are formed in the water core rear end and are used for passing liquid medicine, the water passing grooves are concave, and the water core rear end is fixedly connected with the side wall of the spray head in an interference mode;

the water outlet pipe 12 is hollow, the side wall of the water outlet pipe is fixedly connected with the side wall of the spray head in an interference manner, and the upper end of the water outlet pipe is connected with the lower end of the water core;

the water outlet pipe, the water core, the cyclone groove and the spray holes sequentially form a communicated liquid medicine flow passage.

The device for providing the medicine source is a pusher assembly 2, the pusher assembly comprises a pusher cylinder 21 and a push rod 23, the pusher assembly 2 is detachably arranged in the spray head, and the tail end of the push rod 23 extends out of the tail end of the pusher cylinder 21.

In still another embodiment of the present utility model, the proximal end of the nozzle 11 is provided with a limiting structure 3, and the length from the nozzle hole to the limiting structure 3 is 20mm to 30mm, more preferably 22mm to 28mm, still more preferably 24mm to 26mm; most preferably 25mm.

In still another embodiment of the present utility model, as shown in fig. 5, the water core 13 is circumferentially provided with a water passing groove 133, the water core includes a water core front end 131 and a water core rear end 132, the water passing groove 133 is disposed at the water core rear end 132, an end of the water core rear end 132 is concave and a concave is communicated with the water passing groove 133, and an end of the water core front end 131 is a circular plane.

In still another embodiment of the present utility model, the connection manner between the nozzle 11 and the rear end 132 of the water core is an interference connection, a clamping connection or a threaded connection, and more preferably, an interference connection.

In still another embodiment of the present utility model, the device for spraying the liquid medicine onto the nasal olfactory region is made of PP material.

In yet another embodiment of the present utility model, the head end of the push rod 23 is also provided with a butyl rubber plug to increase the tightness.

In a further embodiment of the present utility model, the tail end of the push rod 23 is detachably provided with a dosing clip for removing air in the cavity and filling the liquid medicine and dosing the liquid medicine to the nasal olfactory region; the dosing clip may be of a conventional dosing clip construction in the art, and is not limited thereto, and is not shown in the drawings for the purpose of enabling dosing.

In yet another embodiment of the present utility model, the head-end liquid suction port of the injector assembly 2 has an inner diameter that is greater than the inner diameter of the outlet tube 12.

In yet another embodiment of the present utility model, the inner diameter of the injector cartridge 21 is 2.5 to 3.5mm.

The operation and use method of the utility model for spraying the liquid medicine to the nasal cavity olfactory region is as follows, as shown in figures 1-5:

1) Sucking the liquid medicine: the pipette head assembly 4 is lifted up, the pipette head assembly 4 is mounted on the head of the syringe assembly 2, the pipette head cap 41 is removed, and the drug solution is sucked from the drug vial.

2) Mounting the injector assembly 2 into the spray head 1: the injector assembly 1 is mounted into the nozzle 11 using the injector cap 41 to remove the pipette tip 42 from the injector head, hold the injector cartridge.

3) Emptying and quantifying: the quantitative clamp is fixed on the tail of the push rod 23, the push rod 23 is pushed to the quantitative clamp, and the nasal spray device finishes quantitative administration at the moment, so that nasal administration can be carried out.

4) Nasal administration: taking out the quantitative clamp, clamping the spray head 11 by an index finger and a middle finger, enabling the patient to lie flat and keep the face upwards, slowly rotating the spray head 11 until the large plane of the administration reference horizontal plane bracket 5 is in a horizontal plane state, stopping rotating, keeping the angle, and slowly inserting the spray head to the limit structure 3 along the nasal septum side of the person to be administered, and stopping inserting. The index finger and the middle finger are placed at the corresponding pressing positions of the spray head 11, the push rod 23 is propped against by the thumb, and the spray head is quickly pushed upwards until the spray head cannot be pushed upwards, for example, the spray head is quickly pushed in 1 second, and then one quantitative spray administration is completed.

The working principle of the fluid flowing process and finally forming spray in the utility model is as follows:

when nasal cavity is administrated, the push rod 23 of the injector is quickly pushed, liquid flows to the water outlet pipe 12, flows to the rear end 132 of the water core after the acceleration action of the water outlet pipe 12, and reaches the spray orifice vortex chamber formed by the circular plane of the front end 131 of the water core and the plane of the cyclone groove positioned on the inner wall of the spray head 11 through the spray channel, and when passing through the spray orifice vortex chamber, the liquid forms a plurality of liquid flows through the channel of the cyclone groove to collide at the spray orifice to form mist, namely tiny particles, so that a spray effect is formed.

It is apparent that the above examples are given by way of illustration only and are not limiting of the embodiments. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. While obvious variations or modifications are contemplated as falling within the scope of the present application.

It is apparent that the above examples are given by way of illustration only and are not limiting of the embodiments. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. While obvious variations or modifications are contemplated as falling within the scope of the present application.

Claims (11)

1. A spray head for ensuring the administration parallelism of nasal and olfactory regions, comprising:

i) The spray head comprises a spray head top end and a spray head distal end, a cyclone groove is arranged on the inner wall of the spray head top end, a circular spray hole is arranged in the center of the spray head top end, the center of the cyclone groove is concentric with the spray hole, and the spray head top end is of a concave bowl bottom type structure;

ii) a dosing reference plane support mounted and fixed on the distal sidewall of the spray head by interference or snap fit;

iii) The water core is integrally formed and is divided into a water core front end and a water core rear end, the diameter of the water core rear end is larger than that of the water core front end, one or more water passing grooves are formed in the water core rear end and are used for passing liquid medicine, the water passing grooves are concave, and the water core rear end is fixedly connected with the side wall of the spray head in an interference mode;

iv) a water outlet pipe, wherein the side wall of the water outlet pipe is fixedly connected with the side wall of the spray head in an interference manner, and the upper end of the water outlet pipe is connected with the lower end of the water core;

the water outlet pipe, the water core, the cyclone groove and the spray holes sequentially form a communicated liquid medicine flow passage.

2. The spray head according to claim 1, wherein one end of the administration reference plane support is provided with a U-shaped part, the U-shaped part is connected to the spray head in an interference or buckling manner, the other end of the administration reference plane support is provided with a plane-shaped part, and the plane-shaped part forms a certain included angle with the central line of the spray head; the U-shaped portion and the planar portion are connected by a connecting mechanism, for example, the connecting mechanism may be linear or curved.

3. The spray head of claim 2 wherein the included angle is 50 degrees.

4. The spray head of claim 2 wherein the cyclone channel has three lobes evenly distributed circumferentially.

5. The spray head of claim 4 wherein the front end of the wick is uniformly cylindrical and the front end of the wick has a rounded end surface and forms a swirl chamber with the cyclone tube.

6. The spray head of claim 5, wherein the water passing grooves extend in parallel along the water mandrel direction and are uniformly arranged along the circumferential direction.

7. The spray head according to claim 6, wherein a spacing structure is further provided outside the spray head, and the spacing structure is spaced from the spray orifice by a distance of 2-3 cm, for example, 2.5cm.

8. A device for ensuring parallelism of nasal-olfactory administration comprising a spray head according to any one of claims 1 to 7, further comprising: a means for providing a source of medication.

9. The device for ensuring the parallelism of nasal and olfactory administration of claim 8, wherein the means for providing a source of medication is a syringe assembly comprising a syringe barrel, a plunger, and the syringe assembly is removably disposed within the spray head.

10. The device for ensuring the administration parallelism of the nasal and olfactory region according to claim 8, wherein the device for ensuring the administration parallelism of the nasal and olfactory region is made of PP material.

11. The device for ensuring the drug delivery parallelism of the nasal and olfactory region according to claim 9, wherein the head end of the push rod is also provided with a butyl rubber plug;

and/or the tail end of the push rod extends out of the tail end of the injector cylinder;

and/or, the diameter of the head end of the injector assembly is larger than the diameter of the water outlet pipe.