CN220650470U - Dry-type fluorescence immunoassay device - Google Patents
Dry-type fluorescence immunoassay device Download PDFInfo
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- CN220650470U CN220650470U CN202322191797.5U CN202322191797U CN220650470U CN 220650470 U CN220650470 U CN 220650470U CN 202322191797 U CN202322191797 U CN 202322191797U CN 220650470 U CN220650470 U CN 220650470U
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- turntable
- immunoassay device
- guide rail
- support
- dry
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- 238000003018 immunoassay Methods 0.000 title claims abstract description 29
- 238000001514 detection method Methods 0.000 claims abstract description 37
- 238000001917 fluorescence detection Methods 0.000 claims abstract description 31
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 29
- 238000007599 discharging Methods 0.000 claims description 8
- 230000005284 excitation Effects 0.000 claims description 6
- 238000004458 analytical method Methods 0.000 claims description 5
- 230000004907 flux Effects 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 238000004064 recycling Methods 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The utility model discloses a dry-type fluorescence immunoassay device, which belongs to the technical field of medical detection equipment and comprises a turntable to be detected, a bracket, a code scanning assembly, a fluorescence detection assembly, an unloading assembly and a top plate, wherein the turntable to be detected is rotatably arranged on the bracket, a plurality of reagent cards to be detected are arranged on the turntable to be detected, the top plate is fixedly arranged on the bracket and is positioned above the turntable to be detected, the code scanning assembly and the fluorescence detection assembly are arranged on the top plate in a staggered mode, the unloading assembly is arranged on the top plate and is positioned on one side of the fluorescence detection assembly, the unloading assembly comprises a push rod, and the push rod is positioned between the top plate and the turntable to be detected and is used for pushing the detected reagent cards to be detected out of the turntable to be detected. The fluorescent detection device is installed in a modularized mode, is compact in structure, large in detection flux, small in occupied space and low in production cost, and can be widely applied to the field of fluorescent detection medical equipment.
Description
Technical Field
The utility model relates to the technical field of medical detection equipment, in particular to a dry type fluorescence immunoassay device.
Background
The fluorescent immunoassay method is a method combining the specificity of an immunological reaction and the sensitivity of a fluorescent technology, and the dry fluorescent detection technology uses a reagent card to be detected as a carrier and utilizes the fluorescent immunoassay method to realize qualitative or quantitative analysis of the content of a substance in a detection sample. The method has the advantages of high sensitivity, strong specificity, simple method and the like, and is widely applied to the field of medical detection.
The traditional dry-type fluorescence immunoassay device structure comprises mechanisms such as card feeding, rotating disc, detection and unloading, wherein a code scanning assembly and a fluorescence detection assembly are integrated, the problems of signal interference and movement stroke increase exist, and in addition, the whole structure of the device is complex, the occupied space is large, and the disassembly and assembly are inconvenient.
Disclosure of Invention
In order to overcome the defects in the prior art, the utility model aims to provide a dry type fluorescence immunoassay device which is installed in a modularized mode and has a compact structure.
The utility model adopts the following technical scheme:
the utility model provides a dry-type fluorescence immunoassay device, includes carousel, support, the code scanning subassembly, fluorescence detection subassembly, uninstallation subassembly, still includes the roof, the carousel that awaits measuring rotates and installs on the support, install a plurality of reagent card that awaits measuring on the carousel that awaits measuring, roof fixed mounting is in on the support and be located the carousel top that awaits measuring, the code scanning subassembly with the fluorescence detection subassembly arrange in with the high-low dislocation form on the roof, the uninstallation subassembly sets up on the roof and be located fluorescence detection subassembly one side, the uninstallation subassembly includes the push rod, the push rod is located the roof with between the carousel that awaits measuring for with the reagent card that awaits measuring that has detected pushes away the carousel that awaits measuring.
Further, the unloading assembly further comprises a driving piece and a card discharging box, the turntable to be tested comprises a turntable, a plurality of turntable clamping grooves for installing the reagent cards to be tested are uniformly distributed in the radial direction of the turntable, the card discharging box is arranged on the support and located outside the turntable clamping grooves, and the driving piece drives the push rod to move so as to push the detected reagent cards to be tested out of the turntable to the card discharging box.
Further, the driving piece comprises a second motor, a second guide rail, a second sliding block, a second idler pulley and a second belt, wherein the second motor and the second guide rail 、 The second idler pulley is installed on the roof, the second belt winds around the shaft of the second motor on the second idler pulley, the extending direction of the second guide rail is parallel to the length direction of the second belt, the second slider is slidably installed on the second guide rail and fixedly connected with the second belt, and the push rod is fixedly connected with the second slider.
Further, the fluorescence detection assembly comprises a horizontal driving part and a photoelectric detection part, the photoelectric detection part comprises an excitation light source and a photoelectric detection unit, the horizontal driving part drives the photoelectric detection part to move in place, and the excitation light source irradiates the reagent card to be detected at a preset angle and the photoelectric detection unit receives a fluorescence signal for analysis.
Further, the horizontal driving part comprises a first motor, a first guide rail, a first sliding block, a first idler pulley and a first belt, wherein the first motor and the first guide rail 、 The first idler wheels are all arranged on the top plate, the first belt is wound on the shaft of the first motor and the first idler wheels, and the first guide railThe extending direction is parallel to the length direction of the first belt, the first sliding block is slidably mounted on the first guide rail and fixedly connected with the first belt, and the photoelectric detection part is fixedly connected with the first sliding block.
Further, the extending direction of the first guide rail is parallel to the extending direction of the second guide rail.
Further, the fluorescence detection assembly further comprises an optocoupler sensor and an optocoupler baffle, wherein the optocoupler sensor is installed on the support and located below the support, and the optocoupler baffle is arranged below the support and synchronously rotates along with the turntable to be detected.
Further, the dry-type fluorescence immunoassay device further comprises a shell, wherein the shell is provided with a containing cavity, and the turntable to be tested, the support, the code scanning assembly, the fluorescence detection assembly and the unloading assembly are all located in the containing cavity.
Further, the casing includes preceding shell, backshell, preceding shell with fixed connection can be dismantled to the backshell, preceding shell is equipped with the viewing aperture, the backshell is equipped with out the bayonet socket, uninstallation subassembly still includes out the cartridge, it is in to go out the cartridge setting on the support and be located one carousel centre gripping groove is outside, it is equipped with out the centre gripping groove to go out the cartridge, go out the centre gripping groove with go out the bayonet socket intercommunication.
Further, the dry-type fluorescence immunoassay device further comprises a bottom plate, the bottom plate is installed in the shell, the support is movably installed on the bottom plate, the support comprises a mounting frame and a supporting frame, the turntable to be tested is rotatably installed in the mounting frame, and the supporting frame is located below the mounting frame and is fixedly connected with the mounting frame vertically.
Compared with the prior art, the dry type fluorescence immunoassay device comprises a turntable to be tested, a bracket, a code scanning assembly, a fluorescence detection assembly, an unloading assembly and a top plate, wherein the turntable to be tested is rotatably arranged on the bracket, a plurality of reagent cards to be tested are arranged on the turntable to be tested, the top plate is fixedly arranged on the bracket and positioned above the turntable to be tested, the code scanning assembly and the fluorescence detection assembly are arranged on the top plate in a staggered mode, the unloading assembly is arranged on the top plate and positioned on one side of the fluorescence detection assembly, the unloading assembly comprises a push rod, and the push rod is positioned between the top plate and the turntable to be tested and is used for pushing the detected reagent cards to be tested out of the turntable to be tested. The application is in use, firstly a plurality of reagent cards to be tested are mounted on the turntable, then the turntable is driven to rotate, the code scanning component scans codes of the reagent cards to be tested firstly, the fluorescent detection component performs fluorescent detection analysis on the reagent cards to be tested, namely, the code scanning component performs time-sharing detection on the code scanning and the fluorescent detection to avoid signal interference, and finally the detected reagent cards to be tested are pushed out of the turntable to be tested to the card outlet box through the push rod for recycling. The fluorescent detection device is installed in a modularized mode, is compact in structure, large in detection flux, small in occupied space and low in production cost, and can be widely applied to the field of fluorescent detection medical equipment.
Drawings
FIG. 1 is an assembly view of a dry-type fluorescence immunoassay device of the present utility model;
FIG. 2 is a schematic diagram showing the internal structure of the dry-type fluorescence immunoassay device of FIG. 1;
FIG. 3 is a schematic view of a part of the dry type fluorescence immunoassay apparatus of FIG. 2;
fig. 4 is a schematic diagram showing a bottom structure of the dry type fluorescence immunoassay apparatus of fig. 3.
In the figure: 10. a turntable to be tested; 11. a turntable; 111. a clamping groove; 12. a turntable motor; 20. a bracket; 21. a mounting frame; 22. a support frame; 30. a top plate; 40. a code scanning assembly; 50. a fluorescence detection assembly; 51. a horizontal driving section; 511. a first motor; 512. a first guide rail; 513. a first slider; 514. a first idler; 515. a first belt; 52. a photodetection unit; 53. an optocoupler sensor; 54. an optocoupler baffle; 60. unloading the assembly; 61. a driving member; 611. a second motor; 612. a second guide rail; 613. a second slider; 614. a second idler; 615. a second belt; 62. a push rod; 63. outputting a card box; 70. a housing; 71. a front shell; 711. an observation port; 72. a rear case; 721. a bayonet; 80. a bottom plate; 90. and a reagent card to be tested.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
It will be understood that when an element is referred to as being "fixed to" another element, it can be directly on the other element or be present as another intermediate element through which the element is fixed. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. When an element is referred to as being "disposed on" another element, it can be directly on the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for illustrative purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model belongs. The terminology used herein in the description of the utility model is for the purpose of describing particular embodiments only and is not intended to be limiting of the utility model. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
Fig. 1-4 show a dry-type fluorescence immunoassay apparatus according to the present utility model, which comprises a turntable 10 to be measured, a bracket 20, a top plate 30, a code scanning assembly 40, a fluorescence detection assembly 50, and an unloading assembly 60.
In this embodiment:
the turntable 10 to be tested comprises a turntable 11 and a turntable motor 12, and the turntable 11 and the turntable motor 12 are in driving connection through a connector so as to drive the turntable 11 to rotate. The turntable 11 is rotatably installed in the bracket 20, and a plurality of clamping grooves 111 for installing the reagent cards 90 to be tested are uniformly distributed in the radial direction of the turntable 11.
The support 20 comprises a mounting frame 21 and a supporting frame 22, wherein the turntable 10 to be tested is rotatably mounted in the mounting frame 21, and the supporting frame 22 is positioned below the mounting frame 21 and is fixedly connected with the mounting frame 21 vertically.
The top plate 30 is fixedly mounted on the bracket 20 and is positioned above the turntable 10 to be tested.
The code scanning component 40 and the fluorescence detection component 50 are arranged on the top plate 30 in a staggered mode, so that the code scanning component 40 scans the bar code on the sample, and after the step is finished, the fluorescence detection component 50 detects the reagent card 90 to be detected, namely the code scanning and the fluorescence detection adopt time-sharing detection to avoid signal interference.
The fluorescence detection assembly 50 includes a horizontal driving portion 51, a photoelectric detection portion 52, an optocoupler sensor 53, and an optocoupler shutter 54.
The horizontal driving part 51 includes a first motor 511, a first guide rail 512, a first slider 513, a first idler wheel 514, and a first belt 515, wherein the first motor 511, the first guide rail 512, and the first idler wheel 514 are all mounted on the top plate 30, the first belt 515 is wound around the shaft of the first motor 511 and the first idler wheel 514, the extending direction of the first guide rail 512 is parallel to the length direction of the first belt 515, the first slider 513 is slidably mounted on the first guide rail 512 and fixedly connected with the first belt 515, and the photoelectric detection part 52 is fixedly connected with the first slider 513. The device realizes the small-range movement detection of the photoelectric detection part 52 through the above structure arrangement, and has simple structure.
The photodetection unit 52 includes an excitation light source and a photodetection unit, and after the horizontal driving unit 51 drives the photodetection unit 52 to move in place, the excitation light source irradiates the reagent card 90 to be tested at a predetermined angle, and the photodetection unit receives a fluorescence signal and performs analysis.
An optocoupler sensor 53 is mounted on the support 20 and is located below the support 20.
The optocoupler baffle 54 is disposed below the turntable 10 to be tested and rotates synchronously with the turntable 10 to be tested, so as to determine the zero optocoupler.
The unloading assembly 60 comprises a drive 61, a push rod 62, a discharge cartridge 63.
The driving element 61 includes a second motor 611, a second guide rail 612, a second slider 613, a second idler wheel 614, and a second belt 615, wherein the second motor 611, the second guide rail 612, and the second idler wheel 614 are all mounted on the top plate 30, the second belt 615 is wound on the shaft of the second motor 611 and the second idler wheel 614, the extending direction of the second guide rail 612 is parallel to the length direction of the second belt 615, and the second slider 613 is slidably mounted on the second guide rail 612 and fixedly connected with the second belt 615. In the present embodiment, the extending direction of the first rail 512 is parallel to the extending direction of the second rail 612.
The push rod 62 is located between the top plate 30 and the turntable 10 to be tested and is fixedly connected with the second slider 613, and is used for pushing the tested reagent card 90 out of the turntable 10 to be tested.
The card discharging box 63 is disposed on the support 20 and is located outside a clamping groove 111, and the driving member 61 drives the pushing rod 62 to move so as to push the detected reagent card 90 to be tested out of the turntable 11 into the card discharging box 63.
The casing 70 includes preceding shell 71, backshell 72, and preceding shell 71 and backshell 72 can dismantle fixed connection, form the appearance chamber between preceding shell 71 and the backshell 72, and the carousel 10 that awaits measuring, support 20, roof 30, sweep a yard subassembly 40, fluorescence detection subassembly 50, uninstallation subassembly 60 all are located the appearance intracavity, and preceding shell 71 is equipped with viewing aperture 711, and backshell 72 is equipped with out bayonet 721, goes out the draw-in groove that is equipped with of cartridge 63, goes out the draw-in groove and goes out bayonet 721 intercommunication.
The bottom plate 80 is mounted in the housing 70, and the stand 20 is movably mounted on the bottom plate 80, so that the positions of the stand 20 and the turntable 10 to be measured can be adjusted.
In this application, roof 30 fixed mounting just is located the carousel 10 top that awaits measuring on support 20, sweeps a yard subassembly 40 and fluorescence detection subassembly 50 and arranges on roof 30 with high low dislocation form, and uninstallation subassembly 60 sets up on roof 30 and is located fluorescence detection subassembly 50 one side. The application is in use, firstly, a plurality of reagent cards 90 to be tested are mounted on the turntable 11, then the turntable 11 is driven to rotate, the code scanning component 40 scans codes of the reagent cards 90 to be tested firstly, the fluorescence detection component 50 performs fluorescence detection analysis on the reagent cards 90 to be tested, namely, the code scanning and the fluorescence detection adopt time-sharing detection to avoid signal interference, and finally, the detected reagent cards 90 to be tested are pushed out of the turntable 10 to be tested to the card outlet box 63 for recycling through the push rod 62. The fluorescent detection device is installed in a modularized mode, is compact in structure, large in detection flux, small in occupied space and low in production cost, and can be widely applied to the field of fluorescent detection medical equipment.
The foregoing examples illustrate only a few embodiments of the utility model, which are described in detail and are not to be construed as limiting the scope of the utility model. It should be noted that, for those skilled in the art, it is possible to make several modifications and improvements without departing from the concept of the present utility model, which are equivalent to the above embodiments according to the essential technology of the present utility model, and these are all included in the protection scope of the present utility model.
Claims (10)
1. The utility model provides a dry-type fluorescence immunoassay device, includes carousel, support, sweep a yard subassembly, fluorescence detection subassembly, uninstallation subassembly that awaits measuring, its characterized in that: still include the roof, the carousel that awaits measuring rotates to be installed on the support, install a plurality of reagent card that awaits measuring on the carousel that awaits measuring, roof fixed mounting is in on the support and be located the carousel top that awaits measuring, sweep a yard subassembly with fluorescence detection subassembly arrange in with the height dislocation form on the roof, the uninstallation subassembly sets up on the roof and be located fluorescence detection subassembly one side, the uninstallation subassembly includes the push rod, the push rod is located the roof with between the carousel that awaits measuring for with the reagent card that awaits measuring after detecting pushes away the carousel that awaits measuring.
2. The dry fluorescent immunoassay device of claim 1, wherein: the unloading assembly further comprises a driving piece and a card discharging box, the turntable to be tested comprises a turntable, a plurality of turntable clamping grooves used for installing the reagent cards to be tested are uniformly distributed in the radial direction of the turntable, the card discharging box is arranged on the support and located outside the turntable clamping grooves, and the driving piece drives the push rod to move so as to push the detected reagent cards to be tested out of the turntable to the card discharging box.
3. According to claim 2The dry type fluorescence immunoassay device is characterized in that: the driving piece comprises a second motor, a second guide rail, a second sliding block, a second idler pulley and a second belt, wherein the second motor and the second guide rail 、 The second idler pulley is installed on the roof, the second belt winds around the shaft of the second motor on the second idler pulley, the extending direction of the second guide rail is parallel to the length direction of the second belt, the second slider is slidably installed on the second guide rail and fixedly connected with the second belt, and the push rod is fixedly connected with the second slider.
4. The dry fluorescent immunoassay device of claim 3, wherein: the fluorescence detection assembly comprises a horizontal driving part and a photoelectric detection part, wherein the photoelectric detection part comprises an excitation light source and a photoelectric detection unit, the horizontal driving part drives the photoelectric detection part to move in place, and the excitation light source irradiates the reagent card to be detected at a preset angle and the photoelectric detection unit receives a fluorescence signal for analysis.
5. The dry fluorescent immunoassay device of claim 4, wherein: the horizontal driving part comprises a first motor, a first guide rail, a first sliding block, a first idler pulley and a first belt, wherein the first motor and the first guide rail 、 The first idler pulley is installed on the top plate, the first belt winds around the shaft of the first motor and is arranged on the first idler pulley, the extending direction of the first guide rail is parallel to the length direction of the first belt, the first slider is slidably installed on the first guide rail and is fixedly connected with the first belt, and the photoelectric detection part is fixedly connected with the first slider.
6. The dry fluorescent immunoassay device of claim 5, wherein: the extending direction of the first guide rail is parallel to the extending direction of the second guide rail.
7. The dry fluorescent immunoassay device of claim 1, wherein: the fluorescence detection assembly further comprises an optocoupler sensor and an optocoupler baffle, wherein the optocoupler sensor is installed on the support and located below the support, and the optocoupler baffle is arranged below the support and synchronously rotates along with the turntable to be detected.
8. The dry fluorescent immunoassay device of claim 1, wherein: the dry-type fluorescence immunoassay device further comprises a shell, wherein the shell is provided with a containing cavity, and the turntable to be tested, the support, the code scanning assembly, the fluorescence detection assembly and the unloading assembly are all located in the containing cavity.
9. The dry fluorescent immunoassay device of claim 8, wherein: the shell comprises a front shell and a rear shell, the front shell is detachably and fixedly connected with the rear shell, the front shell is provided with an observation port, the rear shell is provided with a bayonet outlet, the unloading assembly further comprises a card outlet box, the card outlet box is arranged on the support and located outside the turntable clamping groove, the card outlet box is provided with a clamping groove, and the clamping groove is communicated with the bayonet outlet.
10. The dry fluorescent immunoassay device of claim 8, wherein: the dry-type fluorescence immunoassay device further comprises a bottom plate, the bottom plate is installed in the shell, the support is movably installed on the bottom plate, the support comprises a mounting frame and a supporting frame, the turntable to be tested is rotatably installed in the mounting frame, and the supporting frame is located below the mounting frame and is fixedly connected with the mounting frame vertically.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322191797.5U CN220650470U (en) | 2023-08-15 | 2023-08-15 | Dry-type fluorescence immunoassay device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322191797.5U CN220650470U (en) | 2023-08-15 | 2023-08-15 | Dry-type fluorescence immunoassay device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220650470U true CN220650470U (en) | 2024-03-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322191797.5U Active CN220650470U (en) | 2023-08-15 | 2023-08-15 | Dry-type fluorescence immunoassay device |
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| Country | Link |
|---|---|
| CN (1) | CN220650470U (en) |
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2023
- 2023-08-15 CN CN202322191797.5U patent/CN220650470U/en active Active
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