CN214585460U

CN214585460U - Immunoassay analyzer

Info

Publication number: CN214585460U
Application number: CN202120561209.0U
Authority: CN
Inventors: 胡今科; 徐佳; 申东晋; 王振华; 于占洋
Original assignee: Hunan Dadao Biological Engineering Co ltd
Current assignee: Hunan Dadao Biological Engineering Co ltd
Priority date: 2021-03-18
Filing date: 2021-03-18
Publication date: 2021-11-02
Anticipated expiration: 2031-03-18

Abstract

The utility model discloses an immunoassay appearance, immunoassay appearance includes: the test device comprises a shell, a test device and a control device, wherein the interior of the shell is provided with a test area, the test area is used for placing a plurality of test cards, and the plurality of test cards are linearly arranged when placed in the test area; the detection module is movably arranged in the shell; the driving mechanism is in driving connection with the detection module and is used for driving the detection module to move along a straight line so that the detection module can be opposite to any test card placed in the test area; and the test host is electrically connected with the detection module. The detection module is driven by the driving mechanism to do linear motion, can be used for detecting one test card one by one or any one, and has high flexibility and simple structure.

Description

Immunoassay analyzer

Technical Field

The utility model belongs to the technical field of the medical equipment technique and specifically relates to an immunoassay appearance is related to.

Background

The commonly used detection methods for human body samples include colloidal gold immunoassay and fluorescence immunoassay. At present, an integrated immunoassay analyzer capable of performing colloidal gold immunoassay and fluorescence immunoassay is available on the market.

The integrated immunoassay analyzer is provided with a colloidal gold detection module, a fluorescence detection module and a turntable for placing a plurality of test cards. When the colloidal gold is detected, the turntable needs to be rotated, so that all the test cards are detected by the colloidal gold detection module one by one; when fluorescence detection is carried out, the detection of all test cards can be realized only by rotating the turntable and moving the fluorescence detection module, and the structure is complex.

SUMMERY OF THE UTILITY MODEL

The utility model discloses aim at solving one of the technical problem that exists among the prior art at least. Therefore, the utility model provides an immunoassay analyzer with simple structure.

According to the utility model discloses an immunoassay appearance of embodiment, immunoassay appearance includes: the test device comprises a shell, a test device and a control device, wherein the interior of the shell is provided with a test area, the test area is used for placing a plurality of test cards, and the test cards are linearly arranged when placed in the test area; a detection module movably disposed within the housing; the driving mechanism is in driving connection with the detection module and is used for driving the detection module to move along a straight line so that the detection module can be opposite to any test card placed in the test area; and the test host is electrically connected with the detection module.

According to the utility model discloses immunoassay appearance has following technological effect at least:

when the immunoassay analyzer is used, a plurality of test cards can be placed in the test area in a linear arrangement mode; under the drive of the driving mechanism, the detection module can move to a position corresponding to any one test card, so that the sample information in any one test card is obtained; after the detection module obtains the sample information, the detection module can send the sample information to the test host, and the test host completes analysis. The detection module is driven by the driving mechanism to do linear motion, can be used for detecting one test card one by one or any one, and has high flexibility and simple structure.

According to some embodiments of the utility model, the detection module include with the support frame that actuating mechanism drive is connected, set up in test banks spare on the support frame and set up in camera module on the support frame, camera module with test host computer electric connection.

According to some embodiments of the utility model, the test lamp subassembly include first lamp plate and set up in first lamp plate is close to the light source of one side of test area.

According to some embodiments of the utility model, the light source includes first colour light source and second colour light source, first colour light source is colloidal gold and detects and use the light source, second colour light source is fluorescence and detects and use the light source.

According to some embodiments of the utility model, test banks spare with the subassembly interval of making a video recording sets up, just test banks spare is located the subassembly of making a video recording is close to one side of test area, first lamp plate is equipped with the first mouth of dodging, the subassembly of making a video recording includes the camera, the camera with the first mouth of dodging sets up relatively.

According to some embodiments of the utility model, the support frame include first backup pad, with the relative second backup pad that sets up in first backup pad interval and set up in first backup pad with lens hood between the second backup pad, the lens hood first backup pad and the cooperation of second backup pad forms the shading chamber that has the mouth of dodging and the second of shining, shine the mouth with the second dodges the relative setting of mouth, the subassembly of making a video recording with the second dodges the relative setting of mouth and is located the second dodges the mouth and keeps away from one side of shining the mouth, shine the mouth with the test zone sets up relatively, test lamp subassembly set up in the shading chamber.

According to some embodiments of the present invention, the drive mechanism comprises a drive source, a transmission assembly connected to the drive source, the transmission assembly being fixedly connected to the detection module.

According to some embodiments of the utility model, the driving source has the rotation driving axle, the transmission assembly include with rotation driving axle fixed connection's first drive wheel, set up fixedly in second drive wheel and both ends in the shell are cup jointed respectively first drive wheel and the outer drive belt of second drive wheel, first drive wheel with the second drive wheel sets up along predetermineeing the direction interval, detection module and drive belt fixed connection.

According to some embodiments of the utility model, the immunoassay analyzer still include guiding axle and coupling assembling, coupling assembling with drive belt fixed connection, just coupling assembling still with detection module fixed connection, the guiding axle set up in the shell, coupling assembling with the guiding axle direction is connected.

According to some embodiments of the utility model, the immunoassay analyzer still include pilot lamp subassembly, pilot lamp subassembly include a plurality of set up in photoelectric sensor in the shell and with photoelectric sensor communication connection's pilot lamp, it is a plurality of photoelectric sensor is the straight line and arranges, and is a plurality of photoelectric sensor be used for with place in a plurality of test card one-to-one ground of test area sets up relatively.

Drawings

The above and/or additional aspects and advantages of the present invention will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:

fig. 1 is a schematic structural view of an immunoassay analyzer according to an embodiment of the present invention;

fig. 2 is a schematic view of an internal partial structure of an immunoassay analyzer according to an embodiment of the present invention;

fig. 3 is a schematic view of an internal partial structure of an immunoassay analyzer according to an embodiment of the present invention;

fig. 4 is a schematic structural diagram of a detection module according to an embodiment of the present invention.

Reference numerals:

10. a test card; 100. a housing; 110. a slot; 200. a test host; 300. a drive mechanism; 310. a drive source; 311. a rotary drive shaft; 320. a first drive pulley; 330. a second transmission wheel; 340. a transmission belt; 400. a detection module; 410. a support frame; 411. a first support plate; 412. a second support plate; 413. a light shield; 4131. a second avoidance port; 420. testing the lamp assembly; 421. a first avoidance port; 430. a camera assembly; 431. a camera; 500. an indicator light assembly; 510. a second lamp panel; 520. a photosensor; 530. an indicator light; 540. a light guide pillar; 600. a connecting assembly; 610. a splint; 620. a connecting frame; 630. a linear bearing; 700. and a guide shaft.

Detailed Description

Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present invention, and should not be construed as limiting the present invention.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "axial", "radial", "circumferential", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention. Furthermore, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

As shown in fig. 1 and fig. 2, an immunoassay analyzer according to an embodiment includes a housing 100, a test host 200, a driving mechanism 300, and a detection module 400.

The inside of the housing 100 has a test area for placing a plurality of test cards 10, and the plurality of test cards 10 are linearly arranged when placed in the test area; the detection module 400 is movably disposed in the housing 100; the driving mechanism 300 is in driving connection with the detection module 400, and the driving mechanism 300 is used for driving the detection module 400 to move along a straight line, so that the detection module 400 can be opposite to any one of the test cards 10 placed in the test area; the test host 200 is electrically connected to the detection module 400.

When the immunoassay analyzer is used, a plurality of test cards 10 can be placed in the test area in a linear arrangement manner; under the driving of the driving mechanism 300, the detection module 400 can move to a position opposite to any one of the test cards 10, so as to obtain the sample information in any one of the test cards 10; after obtaining the sample information, the detection module 400 can send the sample information to the test host 200, and the test host 200 completes the analysis. The detection module 400 moves linearly under the driving of the driving mechanism 300, and can sequentially or optionally select one test card 10 for detection, so that the flexibility is high, and the structure is simple.

As shown in fig. 1 and 2, in one embodiment, the casing 100 is provided with a slot 110, and the slot 110 has a plurality of sockets arranged along a straight line, each socket is used for the test card 10 to be inserted into, and the test card 10 can enter the test area after being inserted into the socket.

As shown in fig. 2 and 4, in one embodiment, the detection module 400 includes a support frame 410 drivingly connected to the driving mechanism 300, a test lamp assembly 420 disposed on the support frame 410, and a camera assembly 430 disposed on the support frame 410, wherein the camera assembly 430 is electrically connected to the test host 200. The camera module 430 is configured to take a sample on the test card 10, and transmit the obtained image to the test host 200, where the analysis is completed by the test host 200; the test lamp assembly 420 is used for providing a shooting environment for the camera assembly 430, and ensuring an imaging effect.

Specifically, in the gold immunoassay detection, since the camera module 430 can only perform gray scale recognition and the gold strip is dark red, green light is provided through the test lamp module 420, so that the green light is irradiated on the dark red gold strip, and the gold strip can be changed into black, thereby ensuring the imaging effect. In performing the fluorescence immunoassay test, since the fluorescence itself is not visible, ultraviolet rays are supplied through the test lamp assembly 420 to be irradiated on the fluorescence, so that the fluorescence displays a color, providing a photographing environment for the camera assembly 430.

More specifically, the test lamp assembly 420 includes a first lamp panel and a light source disposed on one side of the first lamp panel close to the test area, the light source includes a first color light source and a second color light source, the first color light source is a light source for colloidal gold detection, and the second color light source is a light source for fluorescence detection. Thus, the detection module 400 at least has two functions of colloidal gold detection and fluorescence detection.

The first color light source is a green light source, and the second color light source is an ultraviolet light source.

Specifically, in the embodiment, the light sources are divided into 4 groups, wherein 1 group is a green light source, the other 3 groups are ultraviolet light sources, and the intensities of the ultraviolet rays generated by the 3 groups of ultraviolet light sources are different.

Specifically, in the fluorescence detection, it is necessary to irradiate ultraviolet rays of different intensities depending on the sample concentration so that fluorescence shows a color, and specifically, it is necessary to irradiate the sample with ultraviolet rays of higher intensity as the sample concentration is lower.

More specifically, in the fluorescence detection, the sample is first irradiated with ultraviolet light having the lowest intensity, and if the fluorescence on the sample does not show a color, the sample is irradiated with ultraviolet light having a higher intensity until the fluorescence on the sample shows a color.

As shown in fig. 2 and 4, in one embodiment, the test lamp assembly 420 and the camera assembly 430 are disposed at an interval, the test lamp assembly 420 is located on one side of the camera assembly 430 close to the test area, the first lamp panel is provided with a first avoidance opening 421, the camera assembly 430 includes a camera 431, and the camera 431 is disposed opposite to the first avoidance opening 421. In this way, the camera 431 can photograph the sample information on the test card 10 through the first escape opening 421.

Specifically, first lamp plate sets up in the below of subassembly 430 of making a video recording, and the first mouth 421 of dodging of first lamp plate is relative with camera 431, and when detection module 400 moved a certain test card 10 top, first light source can send and shine the light on this test card 10, and camera 431 can shoot the sample image on the test card 10.

In one embodiment, the supporting frame 410 includes a first supporting plate 411, a second supporting plate 412 disposed opposite to the first supporting plate 411 at a distance, and a light-shielding cover 413 disposed between the first supporting plate 411 and the second supporting plate 412, the light-shielding cover 413, the first supporting plate 411, and the second supporting plate 412 cooperate to form a light-shielding cavity having an illumination opening and a second avoidance opening 4131, the illumination opening is disposed opposite to the second avoidance opening 4131, the image capturing assembly 430 is disposed opposite to the second avoidance opening 4131 and on a side of the second avoidance opening 4131 away from the illumination opening, the illumination opening is disposed opposite to the testing area, and the testing assembly 420 is disposed in the light-shielding cavity. The light shield 413, the first support plate 411 and the second support plate 412 can surround the test lamp assembly 420 to prevent light generated by the test lamp assembly 420 from leaking as much as possible, and the light shield 413, the first support plate 411 and the second support plate 412 can prevent external light from mixing with light generated by the test lamp assembly 420 to affect the imaging effect.

Specifically, the first support plate 411 and the second support plate 412 are arranged in the transverse direction, the light shield 413 is arranged between the first support plate 411 and the second support plate 412 and is matched with the first support plate 411 and the second support plate 412 to form a light shielding cavity, the upper side of the light shielding cavity is provided with a second avoidance port 4131 opposite to the camera shooting assembly 430, the lower side of the light shielding cavity is provided with an irradiation port opposite to the second avoidance port 4131, the irradiation port is used for being opposite to the test card 10, and the test lamp assembly 420 is arranged in the light shielding cavity and enables the first avoidance port 421 to be located between the second avoidance port 4131 and the irradiation port. In this way, the camera assembly 430 can photograph the sample on the test card 10 through the second avoidance opening 4131, the first avoidance opening 421 and the irradiation opening.

As shown in fig. 2 and 3, in one embodiment, the driving mechanism 300 includes a driving source 310, and a transmission assembly in driving connection with the driving source 310, wherein the transmission assembly is fixedly connected to the detection module 400, and the driving source 310 is configured to drive the detection module 400 to move through the transmission assembly.

As shown in fig. 3, specifically, the driving source 310 has a rotation driving shaft 311, the driving source 310 is fixedly disposed inside the casing 100, the transmission assembly includes a first transmission wheel 320 fixedly connected to the rotation driving shaft 311, a second transmission wheel 330 fixedly disposed inside the casing 100, and a transmission belt 340 having two ends respectively wound around the first transmission wheel 320 and the second transmission wheel 330, the first transmission wheel 320 and the second transmission wheel 330 are disposed at an interval along a preset direction, and the transmission belt 340 is fixedly connected to the detection module 400. When the driving source 310 is started, the rotating driving shaft 311 rotates, and when the rotating driving shaft 311 rotates, the first driving wheel 320 is driven to rotate, so that the driving belt 340 is driven to operate, and when the driving belt 340 operates, the detection module 400 is driven to move.

Specifically, the driving source 310 is a motor, the first driving wheel 320 is a first belt wheel fixedly sleeved outside the rotating driving shaft 311 of the motor, the second driving wheel 330 is a second belt wheel, the second driving wheel 330 is directly or indirectly fixedly connected with the housing 100 and located in the housing 100, and the spacing direction between the second driving wheel 330 and the first driving wheel 320 is parallel to the arrangement direction of the plurality of test cards 10 placed in the test area.

As shown in fig. 2 and fig. 3, further, the immunoassay analyzer further includes a guiding shaft 700 and a connecting assembly 600, the connecting assembly 600 is fixedly connected to the driving belt 340, the connecting assembly 600 is also fixedly connected to the detecting module 400, the guiding shaft 700 is disposed in the housing 100, and the connecting assembly 600 is connected to the guiding shaft 700 in a guiding manner.

The connecting assembly 600 is used for connecting the transmission belt 340 and the detecting module 400, and the transmission belt 340 drives the connecting assembly 600 to move during operation, so as to drive the detecting module 400 to move. The guide shaft 700 is used for guiding the connecting assembly 600, and the accuracy of the running path of the connecting assembly 600 is ensured.

Specifically, the axial direction of the guide shaft 700 is consistent with the transportation direction of the driving belt 340, in other words, the axial direction of the guide shaft 700 is consistent with the length direction of the driving belt 340, the connecting assembly 600 includes a clamping plate 610 for clamping the driving belt 340 and a connecting frame 620 fixedly connected with the clamping plate 610, the connecting frame 620 is fixedly connected with the supporting frame 410, a linear bearing 630 is arranged on the connecting frame 620, and the linear bearing 630 is sleeved outside the guide shaft 700.

As shown in fig. 2, in one embodiment, the immunoassay analyzer further comprises an indicator light assembly 500, the indicator light assembly 500 comprises a plurality of photoelectric sensors 520 and a plurality of indicator lights 530 in one-to-one communication connection with the plurality of photoelectric sensors 520, the plurality of photoelectric sensors 520 are arranged in a straight line, and the plurality of photoelectric sensors 520 are arranged to be opposite to the plurality of test cards 10 placed in the test area in one-to-one correspondence.

When the test card 10 is inserted into the test area, the test card 10 is opposite to the photoelectric sensor 520, and the photoelectric sensor 520 detects that the test card 10 is inserted into the test area, and feeds back the signal to the indicator lamp 530, and the indicator lamp 530 lights up.

Specifically, the light assembly 500 further includes a second lamp panel 510 disposed in the housing 100, the second lamp panel is located at one side of the test area away from the detection module 400, and the photosensor 520 is disposed at one side of the second lamp panel 510 close to the detection module 400. The immunoassay analyzer further comprises a control module, wherein the photoelectric sensor 520, the indicator lamp 530 and the driving mechanism 300 are electrically connected with the control module, and the control module is in communication connection with the background control system.

The processing chip of the control module may be, but not limited to, a single chip microcomputer, an ARM (Advanced RISC Machine, high-end reduced instruction set Machine), and an FPGA (Field-Programmable Gate Array).

Further, be equipped with a plurality of mounting holes on the shell 100, immunoassay appearance still includes a plurality of leaded light post 540, the one end one-to-one ground of a plurality of leaded light post 540 and a plurality of pilot lamp 530 contact, the mounting hole is worn to locate by the other end. Therefore, the light emitted by the indicator lamp 530 can be displayed through the light guide post 540, which is convenient for the operator to observe.

As shown in fig. 1-4, when the above-mentioned immunoassay analyzer is used, the test card 10 is first inserted into the test area through the slot 110, and the photoelectric sensor 520 detects that the card is inserted; the control module then drives the detection module 400 to move to a position corresponding to a certain test card 10 by the driving mechanism 300, at this time, the camera module 430 shoots the two-dimensional code on the test card 10 and sends the information of the two-dimensional code to the background control system, and the database of the background control system records data such as items to be tested by the test card 10; then the background control system sends the corresponding information to the control module, and the control module controls the indicator lamp 530 to display light of a corresponding color or flash at a certain frequency according to the information fed back by the background control system, so that an operator can know whether the card needs to be incubated or not, how long the card needs to be incubated, and the like; if the card needs to be incubated, the operator instructs to incubate to wait for the incubation to be completed; after the incubation is completed, the detection module 400 performs a corresponding test according to the tested item (colloidal gold detection or fluorescence detection), and the test host 200 completes the analysis.

In the description herein, references to the description of the term "one embodiment," "some embodiments," "an illustrative embodiment," "an example," "a specific example," or "some examples" or the like mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

While embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. An immunoassay analyzer, the immunoassay analyzer comprising:

the test device comprises a shell, a test device and a control device, wherein the interior of the shell is provided with a test area, the test area is used for placing a plurality of test cards, and the test cards are linearly arranged when placed in the test area;

a detection module movably disposed within the housing;

the driving mechanism is in driving connection with the detection module and is used for driving the detection module to move along a straight line so that the detection module can be opposite to any test card placed in the test area; and

and the test host is electrically connected with the detection module.

2. The immunoassay analyzer of claim 1, wherein the detection module comprises a support frame drivingly connected to the driving mechanism, a test lamp assembly disposed on the support frame, and a camera assembly disposed on the support frame, wherein the camera assembly is electrically connected to the test host.

3. The immunoassay analyzer of claim 2, wherein the test lamp assembly comprises a first lamp panel and a light source disposed on a side of the first lamp panel near the test zone.

4. The immunoassay analyzer of claim 3, wherein the light source comprises a first color light source and a second color light source, the first color light source is a light source for colloidal gold detection, and the second color light source is a light source for fluorescence detection.

5. The immunoassay analyzer of claim 3, wherein the test lamp assembly and the camera assembly are arranged at an interval, the test lamp assembly is located on one side of the test area where the camera assembly is close to, the first lamp panel is provided with a first avoidance port, the camera assembly comprises a camera, and the camera and the first avoidance port are arranged oppositely.

6. The immunoassay analyzer of claim 5, wherein the supporting frame comprises a first supporting plate, a second supporting plate disposed opposite to the first supporting plate at a spacing, and a light shield disposed between the first supporting plate and the second supporting plate, wherein the light shield, the first supporting plate and the second supporting plate cooperate to form a light shielding cavity having an irradiation port and a second dodging port, the irradiation port and the second dodging port are disposed opposite to each other, the camera module and the second dodging port are disposed opposite to each other and are located on one side of the second dodging port away from the irradiation port, the irradiation port and the test area are disposed opposite to each other, and the test lamp module is disposed in the light shielding cavity.

7. The immunoassay analyzer of claim 1, wherein the driving mechanism comprises a driving source, and a transmission assembly drivingly connected to the driving source, the transmission assembly being fixedly connected to the detection module.

8. The immunoassay analyzer of claim 7, wherein the driving source has a rotary driving shaft, the transmission assembly includes a first transmission wheel fixedly connected to the rotary driving shaft, a second transmission wheel fixedly disposed in the housing, and a transmission belt wound at both ends thereof outside the first transmission wheel and the second transmission wheel, the first transmission wheel and the second transmission wheel are disposed at an interval along a predetermined direction, and the detection module is fixedly connected to the transmission belt.

9. The immunoassay analyzer of claim 8, further comprising a guide shaft and a connecting assembly, wherein the connecting assembly is fixedly connected with the transmission belt, and the connecting assembly is further fixedly connected with the detection module, the guide shaft is disposed in the housing, and the connecting assembly is connected with the guide shaft in a guiding manner.

10. The immunoassay analyzer of claim 1, further comprising an indicator light assembly, wherein the indicator light assembly comprises a plurality of photoelectric sensors disposed in the housing and an indicator light in communication with the photoelectric sensors, the plurality of photoelectric sensors are arranged in a straight line, and the plurality of photoelectric sensors are disposed opposite to the plurality of test cards disposed in the test area in a one-to-one correspondence.