CN108693146A - Hand held biochemical reaction fluorescence analyser - Google Patents
Hand held biochemical reaction fluorescence analyser Download PDFInfo
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- CN108693146A CN108693146A CN201710217763.5A CN201710217763A CN108693146A CN 108693146 A CN108693146 A CN 108693146A CN 201710217763 A CN201710217763 A CN 201710217763A CN 108693146 A CN108693146 A CN 108693146A
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6402—Atomic fluorescence; Laser induced fluorescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/27—Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a further parameter
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N2021/0106—General arrangement of respective parts
- G01N2021/0112—Apparatus in one mechanical, optical or electronic block
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6495—Miscellaneous methods
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6497—Miscellaneous applications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/02—Mechanical
- G01N2201/022—Casings
- G01N2201/0221—Portable; cableless; compact; hand-held
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Abstract
Disclosure of the invention hand held biochemical reaction fluorescence analyser, including shell and display, it is equipped with integrated circuit board, battery, central processing unit, fluorescent scanning detection module, mobile fluorescent scanning in shell and detects module to realize the drive system of scanning, shell is equipped with test strips insert port, the corresponding enclosure interior of test strips insert port, which is equipped with, accommodates the test chamber that test strips are inserted into, the detection mouth that fluorescent scanning detects module is corresponding with test chamber position, fluorescent scanning detects module and drive system is electrically connected with integrated circuit board, and is controlled by central processing unit.The present invention detects the drive system of module by being equipped with mobile fluorescent scanning in shell so that fluorescent scanning detection module can be moved relative to test strips, greatly reduce the volume of analyzer, easily portable and use.In addition, the interior camera module of setting, external camera module and accessory in shell, can be carried out at the same time electrochemistry, a variety of different detection and analysis such as dry chemical, colloidal gold.
Description
Technical field
Invention belongs to medical instruments field more particularly to a kind of hand held biochemical reaction fluorescence analyser.
Background technology
With the development of science and technology, the device for quick testing of test chemistry and biological substance is more and more, wherein colloidal gold is read
Card instrument (also known as gold mark readout instrument) and immunofluorescence instrument and blood glucose meter, urine examination instrument (small urine instrument, dry chemical method)
Using relatively broad.Colloidal gold chart reader generally includes the main control unit worked normally for controller unit, is surveyed for showing
The screen display unit and image processing unit and optical unit of examination process and test result.Immunofluorescence instrument is
Using fluorescent microsphere/fluorescein or the chelate of quantum dot/rare earth ion, the immunoassay of double antibody is established when by optical system
After the excitation that light source in system passes through specific wavelength, corresponding fluorescence signal can be sent out, signal is passed at optics
It is converted into the concentration unit of test substance after amplifying again by amplified signal system in reason system to carry out fluoroimmunoassay.Separately
Outside, what is be commonly used in life also has blood-sugar detecting instrument, and makees the urine examination instrument (small urine instrument, dry chemical method) of routine urinalysis,
But in above-mentioned four kinds of instruments, only blood-sugar detecting instrument small volume, and colloidal gold chart reader and Immunofluorescence test instrument and urine examination
The volume of instrument is all larger, not readily portable.No matter fluorescence analyser currently on the market, colloidal gold chart reader, blood glucose meter or
Small urine instrument (dry chemical detector) is all equipment independently, and there is no a kind of compact, the portable bodies of hand held
Product smaller colloidal gold chart reader and Immunofluorescence test instrument, more not can be achieved at the same time the detection function of above-mentioned four kinds of instruments
Detector.
Invention content
Invention aims to overcome that existing colloidal gold chart reader and/or Immunofluorescence test instrument volume are larger, using not
Just defect further overcomes an equipment that can only detect a kind of defect of methodology reagent, provides a kind of delicate structure, uses
Convenient, small, portable hand held biochemical reaction fluorescence analyser, and based on fluorescence/colloidal gold analysis system,
It can also be extended to detection simultaneously comprising with electrochemistry, one or more test strips such as dry chemical.
To achieve the above object, designed hand held biochemical reaction fluorescence analyser is invented, it includes shell, the shell
In vivo equipped with fluorescent scanning detection module, the mobile fluorescent scanning detection module with the drive system for realizing scanning, integrated electricity
Road plate, the battery being connected with integrated circuit board, the control system on integrated circuit board;The shell is inserted equipped with test strips
Entrance, the corresponding enclosure interior of the test strips insert port, which is equipped with, accommodates the test chamber that test strips are inserted into, the fluorescent scanning inspection
The detection mouth for surveying module is corresponding with the test chamber position, and the fluorescent scanning detects module and drive system and integrated circuit
Plate is electrically connected.
Preferably, the control system includes central processing unit, memory, communication element, collector.Collector is for adopting
Collect the detection information (such as image, electric signal) of sample, for handling collected information, memory module is used for central processing unit
The information of central processing unit processing is stored, the information that communication module is used to handle central processing unit uploads and download the letter needed
Breath.
Above-mentioned technical proposal is quantitatively detected suitable for immunofluorescence, dry chemical quantitatively detects, latex immunochromatography, time point
Distinguish fluorescence, and be not limited to the example above, using the test paper of scan mode fluorescence detection method, be adaptively adjusted data acquisition and
Hand held biochemical reaction fluorescence analyser of the present invention can be used to be detected after processing method.In addition, the analyzer of the present invention
After optical system (excitation light source such as therein) is adaptively adjusted, apply also for examining using the colloidal gold of ccd image sensor
Examining system.
Further, the drive system includes the lead screw of the output shaft cooperation of lead screw motor and the lead screw motor;It is described
Lead screw is equipped with lead screw sliding block, and the fluorescent scanning detection module is fixed on lead screw sliding block.
Further, the drive system further includes parallel with lead screw between fluorescent scanning detection module and lead screw
The stabilization sliding rail of arrangement, the stabilization slide track bar are equipped with sliding-rail sliding, and the fluorescent scanning detection module passes through sliding-rail sliding
It is fixed on lead screw sliding block.Stabilization sliding rail can be one can also two (be located at fluorescent scanning detection module both sides).
The advantageous effect of above-mentioned further scheme is:By the way that stabilization sliding rail is arranged so that fluorescent scanning detects module can
Smooth sliding improves detection efficiency.
Further, the enclosure interior is additionally provided with the interior camera module for being shot to test strips, the interior camera shooting
The shooting mouth of module is corresponding with the test chamber, and the interior camera module is electrically connected with integrated circuit board.
Further, the interior camera module and fluorescent scanning detection module are arranged in the same side of test chamber, and interior take the photograph
It is detected between module and integrated circuit board as module is located at fluorescent scanning, the fluorescent scanning detection module passes through flexible PCB
It is connected with integrated circuit board, and when fluorescent scanning detection module movement, the jitter range of flexible PCB is in interior camera module
Coverage except.
Further, the shell is equipped with electrochemistry test paper insert port, is set in the corresponding shell of electrochemistry test paper insert port
There is Electrochemical Detection module.
Preferably, it is additionally provided with outer camera module on the shell.
It is further preferred that outer camera module is additionally provided on the shell, the outer camera module and Electrochemical Detection mould
Group becomes one.
Optionally, the outer camera module includes outer camera and flash lamp.
It needs, it, can be with using the external shading accessory or optical accessories being used cooperatively with analyzer of the present invention
Realize colloidal gold quantitatively or semi-quantitatively, a variety of detections such as dry chemical sxemiquantitative, such as 1., which can become DNA, scans fluorescence microscope,
Complete the measurement of DNA molecular size;2. diagnosable HIV and syphilis;3. sperm concentration detects;4. detecting cancer, cutaneum carcinoma;5. thin
Bacterium drug resistance etc. need by equipment carry out Image Acquisition (may increase accessory for picture collection when accuracy -- such as
Increase is in the light accessory, for example is increased optical accessories and improved resolution ratio), known by algorithm built in the machine and computing module
, do not differentiate and compare, calculate and finally show result (or after server end algorithm is upgraded, download to our equipment, according to
It is so that result is obtained by the calculating of this equipment and exports display).
In addition, analyzer can the built-in electronic health record formatted, taken pictures to case history using outer camera module, with interior
The identification that algorithm carries out intelligence is set, comparison, and exported and stored according to the format of regulation.
Preferably, the outer camera includes front camera and/or rear camera.
Preferably, the shell is equipped with electrochemistry test paper insert port, is set in the corresponding shell of electrochemistry test paper insert port
There is Electrochemical Detection module.
Further, capping is equipped at the test strips insert port, the capping is slidably connected or is hinged with the shell.
Further, pluggable test strips holder is equipped in the test chamber, the test strips holder is for being embedded difference
The test strips of model.
Further, the hand held biochemical reaction fluorescence analyser further includes the test strips branch in multiple pluggable test chambers
Frame is equipped with multiple contact switch being electrically connected with integrated circuit board around the test chamber, and each test strips holder is right with it
Lug boss is equipped at the contact switch answered;The contact switch for triggering different detection programs, or plays identification test strips
The function of type.
Preferably, the battery is rechargeable battery, and the shell is equipped with the charge port for battery charging.
Further, the integrated circuit board is arranged in casing upper half point, the fluorescent scanning detection module, drive system
It is arranged in shell lower half portion;The test strips insert port is located at one jiao of shell lower end, and the test chamber is located at one in shell
Side.
Preferably, the shell is equipped with display
Advantageous effect of the invention is:The drive system of module is detected due to being equipped with mobile fluorescent scanning in shell so that glimmering
Optical scanning detection module can be moved relative to test strips, relative to the design of traditional test strips relative scanning detection module movement
For, volume substantially reduces, easily portable and use.In addition, detecting module and interior by the way that fluorescent scanning is arranged in shell
Camera module, external camera module and accessory so that this hand held biochemical reaction fluorescence analyser is in addition to trying fluorescent chromatographic class
Paper slip be detected it is outer, also simultaneously can be to comprising electrochemistry, the one or more including dry chemical and colloidal gold be different
Test strips are detected analysis.
Description of the drawings
Fig. 1 is a kind of front view of embodiment of invention hand held biochemical reaction fluorescence analyser.
Fig. 2 is the rearview of Fig. 1.
Fig. 3 is the schematic cross-sectional view of Fig. 1.
Fig. 4 is the schematic cross-sectional view of the another embodiment of invention hand held biochemical reaction fluorescence analyser.
Fig. 5 is the dimensional structure diagram of the another embodiment of invention hand held biochemical reaction fluorescence analyser.
Fig. 6 is that test strips are inserted into the dimensional structure diagram after shell in Fig. 5.
Fig. 7 is that test strips shown in the visual angles A detect the structural schematic diagram of module with fluorescent scanning in Fig. 6.
In figure, shell 1, display 2, integrated circuit board 3, battery 4, central processing unit 5, fluorescent scanning detection module 6, inspection
Survey mouth 6.1, drive system 7, lead screw motor 7.1, lead screw 7.2, lead screw sliding block 7.3, stabilization sliding rail 7.4, sliding-rail sliding 7.5, examination
Paper slip insert port 8, test chamber 9, outer camera 10, flash lamp 11, capping 12, test strips 13, interior camera module 14, flexible circuit
Plate 15, electrochemistry test paper insert port 16, Electrochemical Detection module 17, electrochemistry test paper 18, charge port 19, memory 20, communication
Element 21, collector 22.
Specific implementation mode
Invention is described in further detail below in conjunction with the drawings and specific embodiments.
Embodiment 1
Hand held biochemical reaction fluorescence analyser as shown in Figures 1 to 3, it includes shell 1 and the display on shell 1
Device 2, shell 1 is interior to be equipped with integrated circuit board 3, the battery 4 being connected with integrated circuit board 3, the control system on integrated circuit board 3
System, fluorescent scanning detection module 6, mobile fluorescent scanning detection module 6 are to realize that the drive system 7 of scanning, shell 1 are equipped with examination
Paper slip insert port 8,8 corresponding shell 1 of test strips insert port are internally provided with the test chamber 9 for accommodating 13 insertions of test paper, and fluorescence is swept
The detection mouth 6.1 for retouching detection module 6 is corresponding with 9 position of test chamber, and fluorescent scanning detects module 6 and drive system 7 and integrates
Circuit board 3 is electrically connected.
Control system includes central processing unit 5, memory 20, communication element 21, collector 22.Collector 22 is for acquiring
The detection information (such as image, electric signal) of sample, for handling collected information, memory 20 is used for central processing unit 5
The information that central processing unit 5 is handled is stored, the information that communication element 21 is used to handle central processing unit 5 uploads and download needs
Information.
It includes the luminous activating system of optics that fluorescent scanning, which detects module 6, and optics receives induction system, signal collection amplification system
System etc., it is the prior art that the luminous activating system of optics, which includes light source, lens group, optical filter, light splitting piece, photomultiplier etc., this
Place does not repeat.Fluorescent scanning detection 6 collected signal of module is sent to central processing unit 5 by collector 22.
Drive system 7 includes the lead screw 7.2 of the output shaft cooperation of lead screw motor 7.1 and lead screw motor 7.1;On lead screw 7.2
Equipped with lead screw sliding block 7.3, fluorescent scanning detection module 6 is fixed on lead screw sliding block 7.3.
Drive system 7 further includes being set to being arranged in parallel with lead screw 7.2 between fluorescent scanning detection module 6 and lead screw 7.2
Stabilization sliding rail 7.4, stabilization sliding rail 7.4 is equipped with sliding-rail sliding 7.5, and it is solid by sliding-rail sliding 7.5 that fluorescent scanning detects module 6
It is scheduled on lead screw sliding block 7.3.Pass through be arranged stabilization sliding rail 7.4 so that fluorescent scanning detect module 6 can smooth sliding, improve inspection
Survey efficiency.Stabilization sliding rail 7.4 may be multiple.
Outer camera module is additionally provided on shell 1.Outer camera module includes outer camera 10 and flash lamp 11.Outer camera 10
Including front camera and/or rear camera.
Capping 12 is equipped at test strips insert port 8, capping 12 is slidably connected or is hinged with shell 1.
Pluggable test strips holder (not shown) is equipped in test chamber 9, test strips holder is for being embedded different model
Test strips.
Hand held biochemical reaction fluorescence analyser further includes that the test strips holder in multiple pluggable test chambers 9 (is schemed not
Show), multiple contact switch (not shown) being electrically connected with integrated circuit board 3 are equipped with around test chamber 9, each test strips holder exists
Lug boss is equipped at corresponding contact switch;Contact switch for triggering different detection programs, or plays identification test paper
The function of type.
Battery 4 is preferably rechargeable battery 4, and shell 1 is equipped with the charge port 19 to charge for battery 4.
Such as Fig. 3, integrated circuit board 3 is arranged in 1 top half of shell, and fluorescent scanning detects module 6, drive system 7 is arranged
In 1 lower half portion of shell;Test strips insert port 8 is located at one jiao of 1 lower end of shell, and test chamber 9 is located at the side in shell 1, test paper
When item 13 is inserted into, face is parallel with 1 side of shell.
Integrated circuit board 3 can also make big plate, tiling to entire shell 1.
Embodiment 2
As shown in figure 4, the structure feature of the present embodiment hand held biochemical reaction fluorescence analyser and the substantially phase of embodiment 1
Together, difference lies in shell 1 is equipped with the electrochemistry test paper insert port 16 for being inserted into electrochemistry test paper 18, and electrochemistry test paper is inserted
It is equipped with Electrochemical Detection module 17 in 16 corresponding shell 1 of entrance.It is additionally provided with inside shell 1 for being shot to test strips 13
Interior camera module 14, the shooting mouth of interior camera module 14 is corresponding with test chamber 9, interior camera module 14 and integrated circuit board 3
Electrical connection.Interior camera module 14 and fluorescent scanning detection module 6 are arranged in the same side of test chamber 9, and interior camera module 14
It is detected between module 6 and integrated circuit board 3 in fluorescent scanning, fluorescent scanning detects module 6 by flexible PCB 15 and integrates
Circuit board 3 is connected, and when fluorescent scanning detection module 6 moves, the jitter range of flexible PCB 15 is in interior camera module 14
Coverage except.Outer camera module is integrally formed with Electrochemical Detection module collection 17.
Embodiment 3
As shown in Fig. 5~7, the present embodiment and the structure of embodiment 1 are essentially identical, and difference lies in test strips insert ports 8
In 1 lower end of corresponding shell center, and test chamber 9 is set among the lower half portion inside shell 1.When test strips 13 are inserted into, item
Face is parallel with shell 1.
Fluorescent scanning detects the detection mouth of module 6 towards test strips.
It should be noted that by the way that the layout inside analyzer is adaptively adjusted, test strips insert port 8 can be not only set to
The bottom edge of shell 1 can also be set to top margin or side.When test strips insert port 8 is set to 1 side of shell, test strips 13 are simultaneously not required to
It is fully inserted into, only it corresponds to the detection zone of the detection mouth of fluorescent scanning detection module 6 and is inserted into shell 1.
It should be pointed out that the interior camera module for being detected to test strips of the present invention, fluorescent scanning detect mould
Group 6 and the internal structure of Electrochemical Detection module are all the prior art.In addition, it is existing skill that part is not described in detail herein
Art.
In use, only needing test strips being inserted into test chamber from test strips insert port 8 and/or inserting electrochemistry test paper 18
Enter 18 insert port of electrochemistry test paper, and start hand held biochemical reaction fluorescence analyser, each component starts work in shell 1
Make, last testing result is shown by display 2.
Claims (18)
1. a kind of hand held biochemical reaction fluorescence analyser, it includes shell, it is characterised in that:It is swept equipped with fluorescence in the shell
Retouch detection module, the mobile fluorescent scanning detects module to realize drive system, integrated circuit board and the integrated circuit of scanning
The connected battery of plate, the control system on integrated circuit board;The shell is equipped with test strips insert port, the test strips
The corresponding enclosure interior of insert port, which is equipped with, accommodates the test chamber that test strips are inserted into, the detection mouth of fluorescent scanning detection module with
The test chamber position is corresponding, and the fluorescent scanning detection module and drive system are electrically connected with integrated circuit board.
2. hand held biochemical reaction fluorescence analyser according to claim 1, it is characterised in that:The drive system includes
The lead screw of the output shaft of lead screw motor and lead screw motor cooperation;The lead screw is equipped with lead screw sliding block, the fluorescent scanning
Detection module is fixed on lead screw sliding block.
3. hand held biochemical reaction fluorescence analyser according to claim 2, it is characterised in that:The drive system is also wrapped
The stabilization sliding rail being arranged in parallel with lead screw between fluorescent scanning detection module and lead screw is included, is set on the stabilization slide track bar
There are sliding-rail sliding, the fluorescent scanning detection module to be fixed on lead screw sliding block by sliding-rail sliding.
4. hand held biochemical reaction fluorescence analyser according to claim 1 or 2 or 3, it is characterised in that:In the shell
Portion is additionally provided with the interior camera module for being shot to test strips, the shooting mouth of the interior camera module and the test chamber phase
Corresponding, the interior camera module is electrically connected with integrated circuit board.
5. hand held biochemical reaction fluorescence analyser according to claim 4, it is characterised in that:The interior camera module and
Fluorescent scanning detection module is arranged in the same side of test chamber, and interior camera module is located at fluorescent scanning detection module and integrated electricity
Between the plate of road, the fluorescent scanning detection module is connected by flexible PCB with integrated circuit board, and when fluorescent scanning detects
When module moves, the jitter range of flexible PCB is except the coverage of interior camera module.
6. hand held biochemical reaction fluorescence analyser according to claim 1 or 2 or 3, it is characterised in that:On the shell
Equipped with electrochemistry test paper insert port, Electrochemical Detection module is equipped in the corresponding shell of electrochemistry test paper insert port.
7. hand held biochemical reaction fluorescence analyser according to claim 1 or 2 or 3, it is characterised in that:On the shell
It is additionally provided with outer camera module.
8. hand held biochemical reaction fluorescence analyser according to claim 6, it is characterised in that:It is additionally provided on the shell
Outer camera module, the outer camera module become one with Electrochemical Detection module.
9. hand held biochemical reaction fluorescence analyser according to claim 8, it is characterised in that:The outer camera module packet
Include outer camera and flash lamp.
10. hand held biochemical reaction fluorescence analyser according to claim 9, it is characterised in that:The outer camera packet
Include front camera and/or rear camera.
11. hand held biochemical reaction fluorescence analyser according to claim 7, it is characterised in that:The shell is equipped with
Electrochemistry test paper insert port, the corresponding shell of electrochemistry test paper insert port is interior to be equipped with Electrochemical Detection module.
12. hand held biochemical reaction fluorescence analyser according to claim 1, it is characterised in that:The test strips are inserted into
Capping is equipped at mouth, the capping is slidably connected or is hinged with the shell.
13. hand held biochemical reaction fluorescence analyser according to claim 1, it is characterised in that:It is set in the test chamber
There are pluggable test strips holder, the test strips holder to be used to be embedded the test strips of different model.
14. hand held biochemical reaction fluorescence analyser according to claim 1, it is characterised in that:The hand held is biochemical
Reaction fluorescence analyser further includes the test strips holder in multiple pluggable test chambers, and multiple and collection is equipped with around the test chamber
At the contact switch of circuit board electrical connection, each test strips holder is equipped with lug boss at corresponding contact switch;It is described
Contact switch for triggering different detection programs, or plays the function of identification test strips type.
15. hand held biochemical reaction fluorescence analyser according to claim 1, it is characterised in that:The battery is that can fill
Battery, the shell are equipped with the charge port for battery charging.
16. hand held biochemical reaction fluorescence analyser according to claim 1, it is characterised in that:The integrated circuit board
It is arranged in casing upper half point, the fluorescent scanning detection module, drive system arrangements are in shell lower half portion;The test strips
Insert port is located at one jiao of shell lower end, and the test chamber is located at the side in shell.
17. hand held biochemical reaction fluorescence analyser according to claim 1, it is characterised in that:The integrated circuit board
It is arranged in casing upper half point, the fluorescent scanning detection module, drive system arrangements are in shell lower half portion;The test strips
Insert port is located among shell lower end, and the test chamber is located at the middle lower portion in shell.
18. hand held biochemical reaction fluorescence analyser according to claim 1, it is characterised in that:The shell is equipped with
Display.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710217763.5A CN108693146A (en) | 2017-04-05 | 2017-04-05 | Hand held biochemical reaction fluorescence analyser |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710217763.5A CN108693146A (en) | 2017-04-05 | 2017-04-05 | Hand held biochemical reaction fluorescence analyser |
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| Publication Number | Publication Date |
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| CN108693146A true CN108693146A (en) | 2018-10-23 |
Family
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