CN207600949U - A kind of modularization up-conversion fluorescence chromatographic test paper excitation apparatus - Google Patents
A kind of modularization up-conversion fluorescence chromatographic test paper excitation apparatus Download PDFInfo
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- CN207600949U CN207600949U CN201721736195.1U CN201721736195U CN207600949U CN 207600949 U CN207600949 U CN 207600949U CN 201721736195 U CN201721736195 U CN 201721736195U CN 207600949 U CN207600949 U CN 207600949U
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- conversion fluorescence
- test paper
- modularization
- laser
- chromatographic test
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Abstract
The utility model discloses a kind of modularization up-conversion fluorescence chromatographic test paper excitation apparatus, including detachably connected upper shell and lower housing, the integrally disposed laser in lower housing, optical box and the circuit unit that power supply can be provided for laser, by the infrared light of laser transmitting up-conversion fluorescence test strips to be measured are reached after the dichroism optical filter filtration clutter in optical box, up-conversion fluorescence particle in excitation chromatography up-conversion fluorescence test strips, generate visible ray, visible ray is when by dichroism optical filter, it can vertically be reflected, enter condenser lens after infrared fileter, infrared fileter can reduce influence of the exciting light for result of taking pictures.User, from peep hole can directly from obtain test paper colour developing result.The device compact overall structure, device can be carried out continuously the detection of a samples up to a hundred, convenient for users to carrying out the quantitative detection of up-conversion fluorescence chromatographic test paper whenever and wherever possible without external power supply.
Description
Technical field
The utility model belongs to biomedical devices technical field, and in particular to a kind of modularization up-conversion fluorescence chromatography examination
Paper excitation apparatus.
Background technology
Up-conversion fluorescence is a kind of anti-Stokes luminescence, it can be excited by the near infrared light that wavelength is 980nm, and sending out can
See light, that is, absorb the long wavelength photons of low energy, launch the short wavelength photons of high-energy.Therefore, with traditional fluoroscopic examination
Technology is compared, up-conversion fluorescence detection technique have high sensitivity, optical stability it is good, without be quenched, without autofluorescence, without bias light
Interference, the not advantages such as injury tissue.At present, upconverting fluorescent material has been widely used for the biologies such as bio-imaging, medicament slow release
Medical domain.Meanwhile the chromatographic test paper for making chromogenic label with up-conversion fluorescence also comes into being.Chromatographic test paper has just in itself
The features such as taking, is quick, is of low cost is further combined so that the test paper is in disease with the very high upper conversion particles of signal-to-noise ratio
Being more widely applied for diagnosis, food security and environmental monitoring etc., shows into the trend quickly to detect Mainstream Platform.
But the detection for up-conversion fluorescence chromatographic test paper at present, it is necessary to coordinate fluorescence excitation and quantitative reading device
It could carry out.At present, there are no the portable instruments dedicated for up-conversion fluorescence ELISA test strip on the market.Researcher is led to
Chang Zihang builds up-conversion fluorescence chromatographic test paper detection platform, but the detection platform space built is big, and need to adjust manually
Exciting light and detection part, the controls such as function, operation dispersion, it is cumbersome, therefore it is difficult to ensure that detection platform repeatability and
Stability.
Utility model content
In order to overcome the problems of the above-mentioned prior art, the purpose of this utility model is to provide turn in a kind of modularization
Fluorescent chromatographic test paper excitation apparatus is changed, the apparatus structure reasonable design, simple operation, repeatability is high, and space is small.
The utility model is to be achieved through the following technical solutions：
A kind of modularization up-conversion fluorescence chromatographic test paper excitation apparatus disclosed in the utility model, including what is be detachably connected
Upper shell and lower housing are equipped with laser, optical box and the circuit unit for laser power supply in lower housing；
One end of optical box is connected with laser, and the other end, which is equipped with, can insert up-conversion fluorescence test strips to be measured
Jack opens up test paper jack on lower casing body sidewall with the jack corresponding position；Upper shell upper surface offers peep hole, when upper
When housing and lower housing lid close, peep hole is corresponding with condenser lens present position；
Condenser lens is equipped in optical detection box top, is set in optical box there are one dichroism optical filter and one
A infrared fileter, infrared fileter are arranged below condenser lens, and dichroism optical filter is inclined at exciter and sends out
In the light path of laser, laser is made to reach the visible ray emitted in up-conversion fluorescence test strips to be measured and is filtered by the dichroism
It can be reflected during piece perpendicular to horizontal plane, into the condenser lens of optical detection box top.
Preferably, the exciter being capable of infrared light of the launch wavelength for 980nm.
Preferably, the dichroism optical filter can penetrate the light that wavelength is more than 800nm.
Preferably, the circuit unit include rechargeable battery, circuit board and voltage-stablizer, circuit board respectively with laser and
Voltage-stablizer is connected, and voltage-stablizer is connected with rechargeable battery.
Preferably, it further includes and is arranged on lower housing to control the power switch of laser works state.
Preferably, upper shell and lower housing surrounding are fixed by screw tapping.
Preferably, a length of 170~185mm of the excitation apparatus, width are 80~95mm, a height of 50~70mm.
Preferably, further including can be by the image read-out of peep hole acquisition testing result.
Preferably, described image reading device is mobile phone, camera or CCD.
Compared with prior art, the utility model has technique effect beneficial below：
The utility model discloses a kind of modularization up-conversion fluorescence chromatographic test paper excitation apparatus, including what is be detachably connected
Upper shell and lower housing integrally disposed laser, optical box and can provide power supply in lower housing for laser
Circuit unit is reached after the dichroism optical filter filtration clutter in optical box by the infrared light of laser transmitting and treated
Up-conversion fluorescence test strips are surveyed, excitation chromatographs the up-conversion fluorescence particle in up-conversion fluorescence test strips, generates visible ray, it is seen that
Light can vertically be reflected when by dichroism optical filter, and condenser lens, infrared fileter are entered after infrared fileter
Influence of the exciting light for result of taking pictures can be reduced.User, from peep hole can directly from obtain test paper colour developing
As a result.The device compact overall structure, device can be carried out continuously up to a hundred without external power supply, the interior circuit unit set of lower housing
The detection of a sample, convenient for users to carrying out the quantitative detection of up-conversion fluorescence chromatographic test paper whenever and wherever possible.Whole device is realized
It up-conversion fluorescence excitation and reads integrated, chromatograph test strip to be measured need to be only inserted into, press power switch, operated
It is very convenient, without professional technician.Meanwhile the device can swash up-conversion fluorescence chromatographic test papers all on the market
Hair and reading, have universality and versatility.
Further, a length of 170~185mm of device, width be 80~95mm, only a height of 50~70mm, hand size, side
Portable belt can be carried out detecting whenever and wherever possible.
Further, circuit unit include rechargeable battery, circuit board and voltage-stablizer, circuit board respectively with laser and surely
Depressor is connected, and voltage-stablizer is connected with rechargeable battery, and rechargeable battery is easy to use, without external power supply.
Description of the drawings
Fig. 1 is the structure diagram of the utility model.
Wherein：1 is upper shell；2 be lower housing；3 be optical box；4 be laser；5 be condenser lens；6 be test paper
Socket；7 be circuit board；8 be rechargeable battery；9 be voltage-stablizer；10 be power switch.
Specific embodiment
The utility model is described in further detail below in conjunction with the accompanying drawings：
Referring to Fig. 1, a kind of modularization up-conversion fluorescence chromatographic test paper excitation apparatus disclosed in the utility model, including removable
Connected upper shell 1 and lower housing 2 are unloaded, is powered equipped with laser 4, optical box 3 and for laser 4 in the lower housing 2
Circuit unit；
One end of optical box 3 is connected with laser 4, and the other end, which is equipped with, can insert up-conversion fluorescence test strips to be measured
Jack, the test paper jack 6 for being inserted into up-conversion fluorescence test strips is opened up on lower casing body sidewall with the jack corresponding position；
Condenser lens 5 is equipped at the top of optical box 3, sets that there are one dichroism optical filter and one are red in optical box 3
Outer optical filter, infrared fileter are arranged on the lower section of condenser lens 5, dichroism optical filter be inclined at exciter 4 send out it is sharp
In the light path of light, laser is made to reach the visible ray emitted in up-conversion fluorescence test strips to be measured and is passing through the dichroism optical filter
When can be reflected perpendicular to horizontal plane, into the condenser lens 5 at the top of optical box 3；
1 upper surface of upper shell offers peep hole, when upper shell 1 and the lid conjunction of lower housing 2, peep hole and condenser lens 5
Present position corresponds to.
Preferably, the angle that dichroism optical filter is obliquely installed is 45 °.
Further including can be by the image read-out of peep hole acquisition testing result.Described image reading device is hand
Machine, camera or CCD.
The exciter 4 being capable of infrared light of the launch wavelength for 980nm；The dichroism optical filter can penetrate wavelength
Light more than 800nm, the infrared fileter being capable of infrared light of the wavelength-filtered for 980nm.
The circuit unit include rechargeable battery 8, circuit board 7 and voltage-stablizer 9, circuit board 7 respectively with laser 4 and surely
Depressor 9 is connected, and voltage-stablizer 9 is connected with rechargeable battery 8.It further includes and is arranged on lower housing 2 to control the work shape of laser 4
The power switch 10 of state.Circuit unit is driven by rechargeable battery 8, ensures the normal operation of detection device.Pass through power switch
The opening and closing of 10 control lasers 4, and coordinate voltage-stablizer 9 to be used together so that laser voltage stabilization at work,
So as to ensure that the laser activity sent out is stablized, repeatability is high, and accuracy is good.
Preferably, a length of 170~185mm of the excitation apparatus, width are 80~95mm, a height of 50~70mm.Device only has
Hand size, very portable, the person of being conveniently operated carries, and can be carried out detecting whenever and wherever possible.
Preferably, upper shell 1 and 2 surrounding of lower housing are fixed by screw tapping.
The modularization up-conversion fluorescence chromatographic test paper excitation apparatus of the utility model, when in use：
The near infrared light of 980nm is sent out by laser 4, it is glimmering via the upper conversion for reaching to be detected after dichroism optical filter
Light chromatographic test paper, the dichroism optical filter can greatly filter out laser 4 to fluorescence while equality strength laser is exported
The light disturbance of signal.The up-conversion fluorescence particle on laser excitation chromatographic test paper by filtering generates visible ray, it is seen that light
It when by dichroism optical filter, can vertically be reflected, condenser lens 5 be entered after infrared fileter, and then schemed again
As reading device capture, infrared fileter can reduce influence of the exciting light for result of taking pictures.Up-conversion fluorescence chromatographic test paper
Optical box 3 can be inserted by test paper jack 6, whole system is by optimizing and combining, delicate structure, spaces compact.Circuit system
System is driven by a rechargeable battery 8, ensures the normal operation of detection device.The system includes circuit board 7, voltage-stablizer 9 and electricity
Source switch 10 forms, and the opening and closing of laser 4 are controlled by power switch 10, and voltage-stablizer 9 is coordinated to be used together, and makes
Laser voltage stabilization at work is obtained, so as to ensure that the laser activity sent out is stablized, repeatability is high, and accuracy is good.
In conclusion modularization up-conversion fluorescence chromatographic test paper excitation apparatus disclosed in the utility model is with following excellent
Gesture：
1st, compact overall structure, device only has hand size, very portable；
2nd, for device without external power supply, rechargeable battery can be carried out continuously the detection of a samples up to a hundred, convenient for users to
When carry out the quantitative detection of up-conversion fluorescence chromatographic test paper everywhere；
3rd, whole device realize up-conversion fluorescence excitation and read it is integrated, anyone only need to be by chromatographic test paper to be measured
Item is inserted into, and presses power switch, operation is very convenient, without professional technician；
4th, the device can be excited and be read to up-conversion fluorescence chromatographic test papers all on the market, have universality and
Versatility.
Claims (10)
1. a kind of modularization up-conversion fluorescence chromatographic test paper excitation apparatus, which is characterized in that including detachably connected upper shell
(1) and lower housing (2), equipped with laser (4), optical box (3) and electricity for laser (4) power supply in lower housing (2)
Road unit；
One end of optical box (3) is connected with laser (4), and the other end, which is equipped with, can insert up-conversion fluorescence test strips to be measured
Jack, open up test paper jack (6) with the jack corresponding position on lower casing body sidewall；Upper shell (1) upper surface offers sight
Hole is examined, when upper shell (1) and lower housing (2) lid conjunction, peep hole is corresponding with condenser lens (5) present position；
Condenser lens (5) is equipped at the top of the optical box (3), sets that there are one dichroism to filter in optical box (3)
Piece and an infrared fileter, infrared fileter are arranged below condenser lens (5), and dichroism optical filter is inclined at sharp
Hair device (4) is sent out in the light path of laser, and laser is made to reach the visible ray emitted in up-conversion fluorescence test strips to be measured by being somebody's turn to do
It can be reflected during dichroism optical filter perpendicular to horizontal plane, into the condenser lens (5) at the top of optical box (3).
2. modularization up-conversion fluorescence chromatographic test paper excitation apparatus according to claim 1, which is characterized in that the excitation
Device (4) being capable of infrared light of the launch wavelength for 980nm.
3. modularization up-conversion fluorescence chromatographic test paper excitation apparatus according to claim 1, which is characterized in that described two to
Color optical filter can penetrate wavelength be more than 800nm light, the infrared fileter can wavelength-filtered be 980nm it is infrared
Light.
4. modularization up-conversion fluorescence chromatographic test paper excitation apparatus according to claim 1, which is characterized in that dichroism
The angle that optical filter is obliquely installed is 45 °.
5. modularization up-conversion fluorescence chromatographic test paper excitation apparatus according to claim 1, which is characterized in that the circuit
Unit include rechargeable battery (8), circuit board (7) and voltage-stablizer (9), circuit board (7) respectively with laser (4) and voltage-stablizer
(9) it is connected, voltage-stablizer (9) is connected with rechargeable battery (8).
6. modularization up-conversion fluorescence chromatographic test paper excitation apparatus according to claim 5, which is characterized in that further include and set
It puts and the power switch (10) for controlling laser (4) working condition is used on lower housing (2).
7. the modularization up-conversion fluorescence chromatographic test paper excitation apparatus according to any one in claim 1~6, feature
It is, upper shell (1) and lower housing (2) surrounding are fixed by screw tapping.
8. the modularization up-conversion fluorescence chromatographic test paper excitation apparatus according to any one in claim 1~6, feature
It is, a length of 170~185mm of the excitation apparatus, width is 80~95mm, a height of 50~70mm.
9. the modularization up-conversion fluorescence chromatographic test paper excitation apparatus according to any one in claim 1~6, feature
It is, further including can be by the image read-out of peep hole acquisition testing result.
10. modularization up-conversion fluorescence chromatographic test paper excitation apparatus according to claim 9, which is characterized in that the figure
As reading device is mobile phone, camera or CCD.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201721736195.1U CN207600949U (en) | 2017-12-13 | 2017-12-13 | A kind of modularization up-conversion fluorescence chromatographic test paper excitation apparatus |
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| CN201721736195.1U CN207600949U (en) | 2017-12-13 | 2017-12-13 | A kind of modularization up-conversion fluorescence chromatographic test paper excitation apparatus |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109187448A (en) * | 2018-07-25 | 2019-01-11 | 西安交通大学 | A kind of multiple target objects dish-style effluent test paper chip and its laser cutting preparation method, application method, application and detection device |
-
2017
- 2017-12-13 CN CN201721736195.1U patent/CN207600949U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109187448A (en) * | 2018-07-25 | 2019-01-11 | 西安交通大学 | A kind of multiple target objects dish-style effluent test paper chip and its laser cutting preparation method, application method, application and detection device |
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| TR01 | Transfer of patent right |
Effective date of registration: 20210508 Address after: 215129 South half of 2nd floor, building 3, 599 Taishan Road, high tech Zone, Suzhou City, Jiangsu Province Patentee after: Huicheng Zhilian Industrial Technology Service (Suzhou) Co.,Ltd. Address before: Beilin District Xianning West Road 710049, Shaanxi city of Xi'an province No. 28 Patentee before: XI'AN JIAOTONG University |
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| TR01 | Transfer of patent right |
Effective date of registration: 20210928 Address after: 215129 South half of floor 2, building 3, No. 599, Taishan Road, high tech Zone, Suzhou, Jiangsu Province Patentee after: Suzhou DianAn Biotechnology Co.,Ltd. Address before: 215129 South half of 2nd floor, building 3, 599 Taishan Road, high tech Zone, Suzhou City, Jiangsu Province Patentee before: Huicheng Zhilian Industrial Technology Service (Suzhou) Co.,Ltd. |
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| TR01 | Transfer of patent right |