KR101920273B1 - Sampler for body fluid analysis device and body fluid analysis device using the same - Google Patents

Sampler for body fluid analysis device and body fluid analysis device using the same Download PDF

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KR101920273B1
KR101920273B1 KR1020160155782A KR20160155782A KR101920273B1 KR 101920273 B1 KR101920273 B1 KR 101920273B1 KR 1020160155782 A KR1020160155782 A KR 1020160155782A KR 20160155782 A KR20160155782 A KR 20160155782A KR 101920273 B1 KR101920273 B1 KR 101920273B1
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sample
base
body fluid
sheet
image
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KR1020160155782A
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Korean (ko)
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KR20180057308A (en
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김지훈
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(주)인트인
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Priority to PCT/KR2017/013317 priority patent/WO2018097585A1/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48785Electrical and electronic details of measuring devices for physical analysis of liquid biological material not specific to a particular test method, e.g. user interface or power supply
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

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  • Life Sciences & Earth Sciences (AREA)
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  • Pathology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
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  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Cell Biology (AREA)
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  • Human Computer Interaction (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to a sample portion having a member for adjusting the amount of a sample so that an optimum sample for testing is collected, and a tester device having the sample portion.
A specimen portion according to the present invention is coated with a body fluid and is detachably attached to an inspection device for inspecting body fluids, wherein a predetermined portion of the first surface is concave than the first surface to form a sheet containing the body fluid Base; And an OPCObo which is formed in a ring shape in which a hole is formed and is coupled to a first surface of the sheet edge to expose the sheet by the hole.

Description

TECHNICAL FIELD [0001] The present invention relates to a sample portion for a body fluid testing device, and a body fluid testing device having the same. [0002]

The present invention relates to a body fluid testing device, and more particularly, to a sample portion having a member for adjusting the amount of a sample so that an optimum sample for testing is collected, and a tester device having the sample portion.

In general, people should visit specialized medical institutions to check their health and physical condition. However, in order to visit a medical institution for a medical examination, it is necessary to take time out of busy work and time, and to conduct uncomfortable and complicated procedures and medical procedures. In particular, even if most people go through these procedures, they can wait for a long period of time to be inspected, while the actual examination and inspection proceed in a very short time. In other words, it takes a great deal of time, money, and effort to receive a checkup and inspection, but there are many inconveniences. Because of this, most people are suffering from severe discomfort and are suffering from pain or discomfort that can not be tolerated.

In order to overcome such inconveniences, various techniques have been developed to check the physical condition by frequently using various advanced equipments to check the physical condition and transmit it to the specialized medical institutions via the network. However, to be.

Rather, the use of a simple tester that has been used from the past is steady, and younger generations are steadily increasing their usage rates because they are convenient to use, require less time and expense, and can check results quickly.

Such a tester uses secretions such as saliva, urine, and sweat that are emitted from the body, such as detecting hormones contained in the secretions, or confirming such matters as the state of the secretions. Such a tester utilizes a change in a state of a component contained in a saliva when a body is subjected to a specific situation, for example, a specific disease, an infection, an abnormality such as an ovulation period, or a specific event. Therefore, tester machines are frequently used because they are relatively easy to use because they are relatively easy to use, and they are available at low cost at any time. Tester machines are widely used for testing such as pregnancy diagnosis, diabetes diagnosis and blood glucose measurement have.

As described above, the tester devices measure the change in the state of the sample using body fluids as a sample, or measure and analyze the components to identify and express the state of the user. For this purpose, general test turrets are provided with sampling means capable of collecting sample liquid. Users apply body fluids to these sampling means for testing and the tester analyzes the state of the body fluids applied to the sample collection means to yield the results of the test.

However, in the case of the conventional tester units and the sampling means provided therein, it is difficult to control the exact amount of the body fluid for measurement, and in particular, the tester unit is contaminated when the sample is excessively sampled.

In addition, in recent years, tester devices have become electronic devices, and various items can be tested as compared with the conventional devices. However, since there are many kinds of electronic tester devices, it is not easy to select a suitable test paper for each tester machine, and the operation of the tester machine is troublesome in many cases.

It is therefore an object of the present invention to provide a sample part equipped with a member for adjusting the amount of a sample so that an optimum sample for testing is collected, and a tester device having the sample part.

It is another object of the present invention to provide a method and apparatus for controlling a body of a user by allowing a member for controlling the amount to generate a chemical reaction according to the state of a body fluid to recognize a user's body condition more accurately and precisely And a tester device having the sample part.

It is still another object of the present invention to provide an apparatus and a method for testing a tester to automatically recognize mounting of a suitable sample portion to prevent misuse of the sample portion and to allow tester machines to operate by the sample portion, And a tester device having the same.

In order to attain the above object, a sample part according to the present invention is a sample part to which body fluids are applied and detachably attached to an inspection device for inspecting body fluids, wherein a predetermined part of the first surface is formed to be concave from the first surface, A base for forming a sheet to be embedded therein; And an optobo formed in a ring shape in which the holes are formed and connected to the first surface of the seat edge so that the sheet is exposed by the holes.

The optocoupler is an absorbing material for absorbing liquid.

And an opaque film is attached to the surface of the optobo to prevent transmission of liquid.

And the opaque film is attached to the surface of the optobob so that the side of the optobob, on which the hole is formed, the inner circumference of the optobob is exposed.

The opbo-bo is characterized by containing an indicator which reacts with body fluid to show a predetermined visibility result.

The opbo-bo is characterized by containing a plurality of indicators that react with different components of body fluids.

And the base on which the sheet is formed is formed of a material through which light is transmitted.

And the base is colored with a predetermined monochromatic color.

The sample portion may include a conductive pattern having an electrode terminal formed on the base.

Wherein the conductive pattern is formed on one of a side surface of the base, a second surface opposite to the first surface of the base, and a portion of the first surface other than the sheet forming position.

In addition, the inspection apparatus according to the present invention includes a sample portion having a base on which a sheet is formed so as to be concave than a first surface so as to contain body fluids, and an optobo to be bonded to the first surface of the base to expose the sheet; A magnifying lens group for magnifying a body fluid to be applied to the sample portion, the magnifying lens group being inserted or ejected from the sample portion; A camera for capturing an image of the body fluid enlarged by the magnifying lens group; A light source unit for supplying light for photographing to the sample unit; And a controller for analyzing the image of the body fluid to generate an analysis result.

And the absorber is formed in a ring shape in which a hole is formed, and is formed of an absorbing material that is coupled to the sheet edge of the base so as to expose the sheet by the hole,

And a non-permeable film is attached to the surface of the observer so as to prevent permeation of liquid.

And the opaque film is attached to the surface of the optobob so that the side of the optobob, on which the hole is formed, the inner circumference of the optobob is exposed.

The optobo is characterized by containing an indicator that reacts with the body fluid to display a predetermined visibility result.

The opbo-bo is characterized by containing a plurality of indicators which react with different components of the body fluids.

The camera captures an image of the opbo-box reacted with the body fluid to generate an image, and the controller analyzes the state of the body fluid by comparing the visibility result of the opbo-box with a previously stored image.

And the base is formed of a light-transmissive material through which light is transmitted.

And the base is colored with a predetermined monochromatic color.

And a switching circuit unit for sensing an insertion or ejection of the sample unit to supply an operation signal to operate at least one of the camera, the light source unit, and the control unit, or to switch the power source to supply power.

The sample portion may include a conductive pattern having an electrode terminal formed on the base.

Wherein the conductive pattern is formed on one of a side surface of the base, a second surface opposite to the first surface of the base, and a portion of the first surface other than the sheet forming position.

Wherein a seating part for supporting or fixing the sample part is formed when the sample part is inserted, and the seating part is in electrical contact with the conductive pattern when the sample part is inserted, and a contact part for electrically connecting the conductive pattern and the switching circuit Is formed.

The sample part and the tester device having the sample part according to the present invention can adjust the amount of the sample so that the optimum sample for the test is collected so that the accurate test can be performed and the test device can be prevented from being contaminated.

In addition, the sample part and the tester device having the sample part according to the present invention allow a chemical reaction according to the state of the body fluid to be generated in a member for controlling the amount of the sample, so that the user's physical condition It is possible to make it possible to grasp more accurately and in detail.

In addition, the sample portion and the tester device having the sample portion according to the present invention can automatically recognize the mounting of the appropriate sample portion so that misuse can be avoided, and the tester devices can be operated by the sample portion, .

1 is a perspective view showing an example of a sample part according to a first embodiment of the present invention;
Fig. 2 is an exploded perspective view of Fig. 1; Fig.
3 is an exemplary view showing a perspective view of a sample portion according to a second embodiment of the present invention.
4 is a cross-sectional exemplary view showing the section of Fig. 3; Fig.
5 is a perspective view showing an example of a testing apparatus in which a sample section according to the first embodiment of the present invention is used.
Fig. 6 is a configuration example showing an internal configuration of Fig. 5; Fig.
7 is a block diagram showing a configuration of a testing apparatus in a block form.
8 is an exemplary diagram for explaining a change in body fluids for pattern analysis;
FIG. 9 is an exemplary view showing a test image using actual body fluid. FIG.
10 is an exemplary view showing an example of a division pattern used for analysis of a test image.
11 is an illustration showing an example in the case where body fluids are semen or vaginal discharge.
FIG. 12 is an exemplary view showing a configuration of a sample portion according to a third embodiment of the present invention; FIG.
13 is an exemplary diagram showing another example of the test apparatus according to the present invention

Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings so that those skilled in the art can easily carry out the present invention. It should be noted that the drawings denoted by the same reference numerals in the drawings denote the same reference numerals whenever possible, in other drawings. In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear. And certain features shown in the drawings are to be enlarged or reduced or simplified for ease of explanation, and the drawings and their components are not necessarily drawn to scale. However, those skilled in the art will readily understand these details.

FIG. 1 is a perspective view showing an example of a sample portion according to a first embodiment of the present invention, and FIG. 2 is an exploded perspective view of FIG.

1 and 2, the sample unit 20 according to the first embodiment of the present invention includes a base 23 and an observer assembly 30, (36) and a film (31).

The sample part 20 is coated with a body fluid to be examined, and serves as a backbone for allowing the camera of the test device (described later with reference to the other drawings) to take a body fluid. To this end, the sample part 20 is composed of a sheet 21 to which a body fluid is applied and a base 23 serving as a handle.

The sheet 21 may be formed integrally with the base 23 and may be formed by concave a part of the surface of the base 23 or may be formed by forming a protruding wall around the region where the sheet 21 is to be formed . Hereinafter, the sheet 21 will be described concavely for the convenience of explanation, but the present invention is not limited thereto. Those skilled in the art will appreciate that the deformation that receives the liquid by the wall is based on the present invention It can be easily realized. Specifically, the sheet 21, which is recessed relative to the surface of the base 23, is coated with a predetermined amount of the sample. In order to uniformly distribute the sample over the entire surface of the sheet 21, . The body fluids may be applied to the sheet 21 and analyzed in the liquid state by the inspection apparatus, or may be analyzed by the inspection apparatus in a state of natural drying after application. This will be described in detail below with reference to other drawings.

The base 23 is formed in the form of a thin plate as shown in FIG. 1. The base 23 is formed of a transparent material such as a transparent synthetic resin such as polycarbonate, polyethylene, or acrylic, or a glass for the transmission of light and clear image strokes. . The sheet 21 may be integrally formed by recessing the sheet 21 when the base 23 is formed for the sake of simplicity of production. Alternatively, the sheet 21 and the base 23 may be manufactured and joined together, The sheet 21 and the base 23 may be formed of different materials. For example, it is also possible to form the sample part by forming the base 23 with the observer 36 described below and combining only the sheet 21 with a transparent synthetic resin or glass. Particularly, the portion of the sheet 21 may be colored in a monochromatic state or a monochromatic film may be adhered on one side in order to clarify the body fluid image, but the present invention is not limited thereto.

The observer assembly 30 is coupled to the surface to which the body fluid of the base 23 is applied to control the amount of body fluid applied to the sheet 21. [ In addition, the observer assembly 30 may use a test strip that is expressed in a predetermined form in response to a component of the body fluid applied to the sheet 21. [

Specifically, the observer assembly 30 may include an observer 36 and a film 31.

The observer 36 may be formed in a ring shape in which a hole 33 corresponding to the sheet 21 is formed at the center as shown in the figure. The optobo 36 is bonded on the base 23 to wrap the sheet 21 to absorb excess body fluids applied to the sheet 21 so that a certain amount of body fluid is received in the sheet 21 It is a role to play. For this purpose, the optobo 36 may be formed of a material capable of absorbing liquid, such as cotton, paper, porous synthetic resin, etc., but the present invention is not limited thereto.

In particular, opsobo 36 may include a test material that reacts with a particular component of body fluids to react with specific components of the body fluids upon application of the body fluids and to cause a specific indication to be made. For example, when the optobo 36 contains Litmus reagent, the opsobo 36 may be discolored by the body fluid to confirm the acidity of the body fluid. In addition, OXOVO 36 may include indicator for various concentration measurement or status measurement such as PH, dislocation, metal ion, hydrogen ion of body fluids, and a combination indicator capable of detecting two or more states. ).

The film 31 may be attached to a surface of the optobobe 36, that is, a surface of the optobobe 36 and the surface of the base 23.

This film 31 is used to prevent the body of the user from touching a portion other than the sheet 23 when the body fluid is applied or to prevent the body fluid applied to the sheet 21 from being directly applied to the opto- 36, respectively. To this end, the film 31 is made of a non-moisture-absorbing, impermeable material such as synthetic resin or rubber, and is joined to the opboub 36 so as to cover the upper surface or the outer circumference of the opbobo 36. Particularly, the film 31 is formed so that the side surface 34 of the hole 33 of the oposubo 36, that is, the inner circumferential portion thereof is exposed, so that the body fluid applied to the sheet 21, Which can be absorbed through the body.

3 and 4 are views illustrating an example of a sample unit according to a second embodiment of the present invention. FIG. 3 is a perspective view of a sample unit according to a second embodiment of the present invention. 3 is a cross-sectional view showing a cross-section of Fig.

3 and 4, the sample unit 120 according to the second embodiment of the present invention includes a base 123 and an observer assembly 130.

The sample portion 120 according to the second embodiment differs from the first embodiment only in the shape of the base 123 and the other structural features are similar to the sample portion 20 according to the first embodiment. Therefore, in describing the second embodiment, detailed description of the similar or the same configuration as the above-described embodiment will be omitted, and explanation will be mainly made on the difference.

The base 123 is formed in a cylindrical shape unlike the first embodiment described above. One end of the base 123 is used as the sheet 121, and the other side is opposed to the camera of the inspection apparatus. To this end, one end can be recessed into the interior of the base 123, as can be seen in the sectional view, with the bottom being flat. However, the present invention is not limited thereto, and the formation and shape of the step portion 124 may be determined by the inspection apparatus .

The observer assembly 130 is coupled to the edge of the sheet 121 at one end of the base 123. The observer assembly 130 includes a film that is coupled to the opto-plastic 136 and the opto-plastic 136 as in the first embodiment described above.

The sample portion 120 of the second embodiment is used in combination with the inspection apparatus in one end and the other end direction.

FIG. 5 is a perspective view showing an example of a testing apparatus in which a sample portion according to the first embodiment of the present invention is used, and FIG. 6 is a configuration diagram showing the internal configuration of FIG. 7 is a block diagram showing the configuration of the testing apparatus in a block form.

5 to 7, the examination apparatus 10 according to the present invention plays a role of grasping the state of the user using the body fluid of the user as a sample. Such an inspection apparatus 10 may be a device for capturing and analyzing body fluids, providing results to the external apparatus, or outputting the result through an external apparatus. Or an external device connected to the inspection apparatus 10, and analyzing the captured image by an external device and providing the captured image to a user. In the detailed description of the present invention, the inspection apparatus 10 will focus on an example of an apparatus for imaging and analyzing body fluids and delivering the results to an external apparatus. However, it should be understood that the present invention is not limited thereto, and various modifications are possible without departing from the scope of the present invention.

Specifically, the inspection apparatus 10 includes a sample unit 20, and the body fluid of the user is applied to the sample unit 20 and is coupled to the inspection apparatus 10. [ When the sample portion 20 to which the body fluids are applied is inspected, the examination device 10 enlarges the sample portion 20 by the camera 110 provided therein to generate a body fluid image, analyzes the generated image And transmits the analysis result to an external device connected by the communication channel. Here, the external device may be a computer system of a company providing professional medical services such as a terminal device such as a user's smart phone, a smart pad, a mobile terminal such as a notebook computer or a fixed computer, a hospital, etc. However, It is not. Thereafter, the gastric device performs more precise analysis using the transmitted analysis result and the body fluid image, or outputs the analysis result to the user or specialized medical institution.

To this end, the inspection apparatus 10 enlarges the body fluid of the sample unit 20 to which the body fluid is applied, and creates the body fluid image data generated by the imaging. Therefore, the inspection apparatus 10 includes a power supply unit 90, an illumination unit 50, a memory 60, a communication unit, a control unit 80, and a camera 110. Here, configurations such as the communication unit, the control unit 80, and the memory 60 may be integrated on one circuit board 16.

The case 11 accommodates and fixes therein a structure for executing the function of the inspection apparatus 10, and protects these structures from external impact or contamination. Such a case 11 is configured to internally divide the configuration so that the image of the body fluid applied to the sheet 21 can be stably photographed and the inspection device 10 is prevented from being contaminated by body fluids, And the inner case 13 so as to stably attach and detach the outer case 21. The case 11 may be provided with an insertion hole 12 for inserting or extracting a sample portion 20 to which a body fluid is to be applied. To serve as a part for fixing the sample part 20 to the correct position. The case 11 is resistant to external impacts such as synthetic resin and metal, and can be made of a light material. However, the case 11 may be formed using tempered glass or wood, and the present invention is not limited thereto. In addition, the case 11 may be provided with an interface 31 through which a cable for transmitting data stored in the memory 60, which is connected to a power supply device for charging, and a lid for replacing the power supply unit 90 may be formed.

The power supply unit 90 supplies power for operation of the inspection apparatus 10. The power supply unit 90 may be replaced with a simple disposable battery or a rechargeable secondary battery. Alternatively, the power supply unit 90 may be connected to an external power supply through a terminal formed in the case 11, . To this end, the case 11 may have an interface terminal connected to an external power source, and may be connected to a user terminal, a portable battery, a charger, and a power source through an interface terminal.

The illumination unit 50 generates light by the light source 52 by a power source transmitted from the power source unit 90 and transmits the generated light to the sample unit 20 to check the image of the body fluid imaged on the sample unit 20 Or photographed. The light source unit 10 is disposed at a position where the light source unit 10 overlaps the camera 110 with the sample unit 20 interposed therebetween so that the light generated from the light source 52 passes through the sample unit 20, . The lighting unit 50 may include a light source circuit 51 for controlling lighting of the light source 52 and the light source 52. The light source circuit 51 may be configured . The light source 52 of the illumination unit 50 is made up of a monochromatic light source that emits monochromatic light such as green, blue, and red, and is capable of sharpening an image of an object to be imaged, such as crystals produced by substances in body fluids or body fluids However, the present invention is not limited thereto. When the light source 52 emits a multicolor light source or a white light source, the sample unit 20 may be colored as described above or a colored film 54 transmitting the light of a specific monochromatic color may be incident on the light source 52 and the sample unit 20 ). ≪ / RTI > In addition, the light source 52, the sample unit 20, and the camera 110 may be configured to be positioned in a straight line as shown in the figure, but the light source 52 or the camera 110 may be a mirror, The position can be changed using the light path changing means.

The memory 60 may receive analysis results obtained by analyzing the body fluid image and the body fluid image captured by the camera 110 from the controller 80, store the analysis results, and store the analysis software for analysis. The memory 60 may be a fixed memory fixed to the circuit board 40, but may be a removable memory such as an SD card or a USB memory.

The communication unit forms a communication channel with the external device, and transmits the body fluid image or the analysis result through the communication channel. The communication unit may be configured using various wired / wireless communication means such as USB, infrared, Wi-Fi, and Bluetooth.

The control unit 80 controls each configuration of the inspection apparatus 10 to capture an image of the body fluid applied to the sample unit 20, analyzes the body fluid image generated by the image capture, and analyzes the state of the user. For this, the controller 80 analyzes the body fluid image using the software stored in the memory 60. In particular, when the analysis result is generated, the control unit 80 transmits the analysis result or the body fluid image to the external device through the communication channel formed between the communication unit and the external device.

In this analysis, analysis of the observer 30 as well as analysis of the body fluid image of the control unit 80 can be performed. Specifically, the reaction represented by the contact between the opbo-boat 30 and body fluids is captured and compared with a pre-stored image to analyze a state that can be determined by the opbo-boat 30 and can be provided to the user through an external device . For example, when the optobob 30 contains a knowledge drug for PH or acid grouping, the optobob 30 is photographed and compared with a pre-stored color chart to determine the acidity / basicity and pH of the user's body fluid It is possible to do.

7 is an exemplary view for explaining an example of a testing apparatus in which a sample portion according to a second embodiment of the present invention is used.

7, an inspection apparatus according to another embodiment of the present invention includes a sheet portion 120 on which a sheet 121 is formed, a magnifying lens 120 for enlarging body fluid applied on the sheet 121 of the sheet portion 120, A guide 144 which is disposed so as to face the second surface 125 of the sheet 121 and which is in close contact with the photographing means for photographing the image of the body fluid expanded through the magnifying lens group, Is disposed so as to face the first surface of the sheet portion 120 on which the sheet 121 is formed in a direction facing the contact portion 140 with the contact portion 140 provided on the other side and the sheet portion 120 interposed therebetween And a light source 210 for supplying light to the sheet 121.

The inspection apparatus 100 according to another embodiment of the present invention is attached to a user terminal having a camera to acquire an image of body fluids through a camera and analyze the acquired image by a program installed in the terminal .

The light source unit 210 serves as a light source that transmits light generated by external light or a light source to the sheet unit 120 so that an image of the body fluid applied to the sheet unit 120 can be captured. The light source unit 210 is formed in a cylindrical shape in which the inside of the body 211 of the light source unit 210 is empty so that light can be transmitted to the lower surface of the sheet 121 which is the second surface 125 of the sheet unit 120. One end of the light source 210 is engaged with the seat part 20 by being fitted into the seating part 122 formed on the side surface of the seat second surface 125 of the seat part 20. When the light source 210 is used, the light source 210 may include a light source, a circuit for driving the light source, a switch, and a power source for operating the light source. Also, when external light is used, the light source unit 210 may be formed of a transparent material, or a hole into which the external light may enter the light source unit 210 may be formed.

 Meanwhile, as described above, the light source provided in the light source unit may be a light source that outputs monochromatic light, and an optical film for converting external light or white light into monochromatic light may be formed in the light source unit, but the present invention is not limited thereto .

The contact portion 140 connects the seat portion 120 and the inspection terminal so that the inspection terminal (not shown) can take a picture of the body fluid applied to the seat portion 120. The contact portion 140 is engaged with the seat portion 120 so that the object portion 141 faces the second surface 9125 of the seat portion 120). The contact portion 140 is also formed in a hollow pipe shape, and an enlarged lens group (not shown) is configured to enlarge and provide an image of the seat portion 120 therein. In particular, by adjusting the length of the rigid body 142 of the contact portion 140, the position of the magnifying lens group 145 is changed, thereby enabling magnification and focus adjustment to be performed, Or when the image of the body fluid is confirmed by the user's interest, the focus and magnification can be controlled, but the present invention is not limited thereto.

On the other hand, a guide 144 is formed at the other end of the contact portion 140. The guide 144 serves to prevent the magnifying lens group from directly contacting the inspection terminal and also to allow the inspection terminal and the magnifying lens group 35 to maintain a constant distance so that accurate magnification adjustment can be performed.

8 to 10 are diagrams for explaining a pattern analysis method according to the present invention, FIG. 8 is an exemplary view for explaining a change in body fluid for pattern analysis, FIG. 9 is a diagram showing a test image using actual body fluid Fig. 10 is an exemplary diagram showing an example of a division pattern used for analyzing a test image.

Referring to Figures 8-10, body fluids, especially saliva (or saliva), can be used as indicators of various symptoms. Among these, the saliva of a woman of childbearing shows a special sign. Specifically, estrogen, a female hormone contained in the saliva of a woman, can predict the ovulation precisely, which can increase the possibility of a pregnant couple suffering from infertility.

Specifically, in the case of women of childbearing age, when the ovulation date is near, the amount of estrogen secretion increases, thereby increasing the salt concentration of the saliva. Therefore, when the saliva is dried for a certain period of time, different salivary crystal structures are exhibited depending on the period of the rain, the transient period and the reproductive period.

For example, when the rain is not available, that is, when the saliva of a woman who does not have ovulation is dried and photographed, an image of a form in which no distinct crystal structure can be found can be obtained as shown in FIG. 8 (a).

An actual photographed image is shown in Fig. 9 (a). As shown in Figs. 5 (a) and 6 (a), no specific crystal structure can be found during the non-fermentation period, and only a part of saliva cells can be identified.

5 (b), the crystallization of the female saliva in the process of transition from the transition period to the fertilization period when the ovulation is carried out in the period of inactivity becomes slightly crystallized, and the crystal form at this time is formed by electrolytes, mucus, And have the shape of circular and longitudinal salivary cells to be formed.

Lastly, when the fertilization phase, that is, the ovulation phase, the fern patterns of the ferns, that is, the crystals extending in one direction as shown in FIG. 5 (c), are clearly displayed. FIG. 9 (b) is an image of the saliva of the actual fertile female. As can be seen from this, it can be seen that the pattern clearly distinguishes from FIG. 9 (a).

The system for determining the state of the body fluid of the present invention analyzes the state of the saliva to check whether the user is a child's reproductive organs, and generates the analyzed information as analysis information and provides the information to the user.

That is, the inspection apparatus implements the image of the captured test image to clarify the crystal line, and confirms whether the crystal line forms a closed curve shape or the leaf shape of the ferns as shown in (c). In particular, The length density of the pattern is confirmed. Through this, it is judged the rain period, the transitional period and the reproductive period, and is provided to the user as analysis information. Here, the discrimination of the image processing and the non-expiration period, the transient period, and the reproductive period can be adjusted according to the density and the pattern of the pattern, so that a detailed description thereof will be omitted in the present invention.

In the case of the image processing, various methods can be used in which the image is reprocessed in black and white, the contrast of the monochrome processing is discriminated, the linearity is determined, and the length and density can be judged therefrom. do.

On the other hand, a partition pattern can be used as shown in FIG. 10 to enhance the accuracy of such image processing and judgment. That is, the analysis information can be generated by checking how many straight lines or elliptical lines exist in the area defined by the pattern (the inner area of the closed line).

Particularly, such a division pattern may be provided in the form of being printed on the lens group 145 of the inspection apparatus or the sample unit 120, or a part of the analysis image may be divided into a division pattern by the inspection apparatus, , It is not intended to limit the invention to the precise form disclosed.

On the other hand, Fig. 11 is an example diagram showing an example in which body fluid is semen or vaginal secretion.

This analytical information can be written on male semen. When the male semen is discriminated by using the state discrimination system of the present invention, it is possible to confirm such things as the number of sperm, the activity of the sperm, and whether or not the sperm is malformed. In particular, It is possible to do so.

A partition pattern can also be used for analysis of such semen, which is shown in Figures 11 (a) and (b). the sperm characteristics can be easily analyzed by discriminating the number, activity, and shape of the sperm located in the lattice pattern formed at the center of (a) and (b). More specifically, it is possible to perform sampling analysis on sperm in a region partitioned by the division pattern, without analyzing both spermatozoa distributed in the first half of the photographed image. Accordingly, the present invention can perform quick analysis, reduce the pattern processing load of the inspection apparatus, and perform analysis more finely.

10 and 11, the partition pattern may be formed in various shapes such as an ellipse and a circle, and an arbitrary position may be designated in addition to the center of the screen. Further, it is possible to confirm the image and apply the division pattern at a high density to perform the analysis, and the present invention is not limited by the presented examples.

In order to analyze the sperm characteristics in the test apparatus of the present invention, a similar method to the above-described saliva analysis is performed. First, the inspection apparatus captures the semen applied to the sample unit 120 to secure a test image. The test apparatus calculates the number of spermatozoa, the distance of movement of a specific sperm, the average of the moving distance, the rotation speed, the rotation speed, and the radius of rotation in a test image. At this time, the inspection apparatus can photograph a plurality of test images and use them to photograph the test images in the form of moving images. At this time, it is possible to confirm the state of the sperm by randomly selecting a specific sperm in the image and determining the sperm characteristics of the selected sperm. It is also possible to increase the accuracy of sperm characterization by selecting a plurality of such sampling sperm.

In addition, the inspection apparatus selects some sperm in the test image, processes the image of the selected sperm into a clear pattern or a monochrome image, and compares the image with a previously stored image or a form conforming to a predetermined condition, It is also possible to discriminate. For example, it is possible to determine whether the sperm in the test image has a normal shape by determining the number of tails (tail shape) per one hull (rounded portion), the bending of the tail portion, and the shape of the hull.

Particularly, in order to facilitate selection and sampling of the spermatozoa in this process, the spermatozoa of the spermatozoa of the spermatozoa of the spermatozoa of the spermatozoa of the spermatozoa Can be analyzed. This makes it easy to select the sampling sperm of the present invention, maintain the consistency of the analysis information, and reduce the burden on the inspection apparatus according to the analysis, thereby enabling quick analysis.

In addition, as in (c), vaginal discharge can be observed to determine the presence or absence of a medical condition such as bacterial vaginosis and vaginitis, and the presence or absence of a medical examination. Specifically, when vaginal discharge is observed using a testing device, only normal vaginal mucosa cells are observed, but when a disease caused by a bacterial infection occurs as shown in (c) of FIG. 11, Substances can be identified. (c) shows a case in which the vaginal acidity increases and the anaerobic bacteria are overproduced by decreasing the secretion of the antimicrobial substance from the inside of the vagina. The vaginal mucosal cells to be adsorbed on the surface of the vaginal mucosal cells by the overgrown anaerobic bacteria So that it becomes possible to confirm such symptoms by the inspection apparatus. As a result, according to the present invention, it is possible to distinguish various states such as the presence of disease, disease name, and ovulation period by enlarging a body secretion such as saliva, vaginal discharge, semen of a male, and performing image analysis and related analysis.

12 is an exemplary view showing a configuration of a sample portion according to a third embodiment of the present invention.

Referring to FIG. 12, the sample unit 320 according to the third embodiment of the present invention includes a base 323 and a conductive pattern 337 formed on the base 323. Although the above-described observer assembly 30 is omitted in the description of the third embodiment, the observer assembly 30 may be configured to include the observer assembly 30, The structure of the assembly 30 is as described above. Hereinafter, in describing the third embodiment, the technical features which are the same as or similar to the technical features described above will be omitted, and technical features will be mainly described.

The sample part 320 is coated with a body fluid to be inspected, and serves as a backbone for allowing the camera of the test device to take a body fluid. The sample part 320 functions as a switch for operating the sample part 20 by attaching or detaching it to the test device or stopping the operation of the sample part 320. For this, a conductive pattern 337 (337a, 337b) may be formed on the sample part 320 and includes a base 323 on which a conductive pattern 337 is formed and a sheet 321 on which body fluid is received.

The base 323 is formed in the form of a thin plate, and is formed of a transparent material to form a sheet 321 for transmitting light and acquiring a clear image. In particular, a conductive pattern 337 may be formed on the base 323. The conductive pattern 337 serves as an electrically connected conductor and is electrically connected to an opto-electronic circuit formed in the test apparatus when the test apparatus sample unit 320 is inserted. The sample part 320 may operate the test device by inserting or allow the test device in operation to recognize the insertion of the sample part 320. Likewise, when the sample unit 320 is removed, it is possible for the test apparatus to recognize this and terminate the operation. For this purpose, the conductive pattern 337 is brought into electrical contact with the opto-electronic circuit to complete the circuit of the sensing circuit portion constituted in the opto-electronic circuit. That is, the conductive pattern 337 connects the disconnected portion of the sensing circuit, is energized through the conductive pattern 337, recognizes the insertion of the sample portion 320 by recognizing it, and performs the operation accordingly, The test apparatus can be turned on so as to be driven.

For this, the conductive patterns 337 (337a, 337b) formed on the base 323 may be formed of one or more, and may be formed as a pair as shown in the figure. In particular, in the case where the conductive patterns 337 are composed of a plurality of one or more pairs, the conductive patterns 337 may be connected to different contacts of the observer circuit, but the present invention is not limited thereto. A pair of conductive patterns connected to the circuit and the cathode circuit is shown as an example. Electrode terminals 338 (338a to 338d) may be formed such that the conductive pattern 337 is in electrical contact with the contact portion formed in the sensing circuit of the switching circuit. The electrode terminals 338 may be formed at the pattern end of one conductive pattern 337, respectively.

Particularly, the conductive pattern 337 of the present invention can be used as a means for separating the sample portion 320 suitable for a test apparatus. For this purpose, the conductive pattern 337 may be positioned at the position of the electrode terminal 338 formed at the end of the conductive pattern 337 Can be formed at an arbitrary predetermined position. The position of the electrode terminal 338 formed on the conductive pattern 337 and the position of the contact portion formed on the detection circuit are formed at predetermined positions so that the sample portion 320 having a different position of the electrode terminal 338 is inserted The operation can be prevented from being performed. Thus, it is possible to allow the test apparatus to recognize and operate whether or not the sample unit 320 is suitable for the test apparatus without a separate verification process. Therefore, when the conductive patterns 337 are composed of a plurality of conductive patterns 337, the shapes of the conductive patterns 337 may be formed so as to have different electrode positions and different electrode positions.

The conductive pattern 337 may be formed on the back surface of the base 323 such that the sheet 321 is formed or a surface other than the surface to which the optobo 36 is attached, Or on the back surface. 12 shows an example in which a sheet 321 is formed on the front surface 323a and a conductive pattern 337 is formed on the back surface. In this case, the conductive pattern 337 may be formed using transparent electrodes so as not to hinder imaging, but the present invention is not limited thereto.

Particularly, when the front end 339 of the sample portion 320, that is, the sample portion 320 is inserted into the test device for the formation of the conductive pattern 337, the portion to be first inserted is extended in the insertion direction, The conductive pattern 337 may be formed in a limited manner so as to prevent image shooting from being hindered. In this case, the conductive pattern 337 can be formed on the same surface as the surface on which the sheet 321 is formed, and a conductive material such as copper (Cu) or a conductive material such as carbon It is possible.

The OBSubo 36 may be coupled to the front end 339 so as to cover the conductive pattern 337. At this time, a short circuit of the conductive pattern 337 is formed between the OBSubo 36 and the conductive pattern 337 An insulating protective layer may be formed.

13 is an exemplary diagram showing another example of the test apparatus according to the present invention.

Referring to FIG. 13, the inspecting apparatus 310 according to the present invention plays a role of grasping the state of a user using a body fluid of a user as a sample, detects insertion of the sample unit 320, And detects the sample unit 320 inserted therein to perform an operation.

For this purpose, an inspection unit 310 is provided with a seating unit 344 for supporting the sample unit 320 when the sample unit 320 is inserted, and a conductive pattern (not shown) formed on the sample unit 320 337 are formed in contact with each other. The contact portions 345 are formed in a plurality of locations corresponding to the positions of the electrode terminals 338 formed on the conductive pattern 337. The contact portions 345 are connected to a detection circuit (not shown). The sensing circuit may electrically connect the switching circuit to the contact portion 345 and the switching circuit 95 may be formed separately from the control portion 80 or may be provided as one function portion of the control portion 80. [ The switching circuit 95 may be provided at the output terminal of the power supply unit 90 so as to control the output of the power supply unit 90 so as to allow the sample unit 320 to be attached or detached, The invention is not limited thereto.

Other technical features of this inspection apparatus are the same as those of the above-described embodiment, and therefore, a detailed description thereof will be omitted.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, . ≪ / RTI > Accordingly, such modifications are deemed to be within the scope of the present invention, and the scope of the present invention should be determined by the following claims.

10: Inspection apparatus 20:
21: Sheet 23, 123: Base
30: opsobo assembly 31: film
32: hole 34; My star
36: Observer

Claims (23)

A specimen portion to which body fluids are applied and to be attached to and detached from an examination apparatus for inspecting body fluids,
A base on which a predetermined portion of the first surface is concave than the first surface to form a sheet containing the body fluid;
A conductive pattern having electrode terminals formed on the base; And
And an optobo formed in a ring shape in which a hole is formed and coupled to a first surface of the seat edge so that the seat is exposed by the hole,
The conductive pattern may include:
A sample part for a body fluid testing device for separating or coupling with a switching circuit part for supplying an operation signal so that at least one of the camera, the light source part and the control part operates as the sample part is attached to and detached from the inspection device, or switching to supply power.
The method according to claim 1,
The opto-
And a liquid absorbing member for absorbing the liquid.
3. The method of claim 2,
And a non-permeable film for preventing permeation of liquid is attached to the surface of the optobo.
The method of claim 3,
The non-
Wherein the sample is attached to the surface of the optobo so that a side surface of the optobo having the hole formed therein is exposed.
3. The method of claim 2,
The opto-
And an indicator for indicating a predetermined visibility result by reacting with body fluids.
6. The method of claim 5,
The opto-
Wherein a plurality of indicators for reacting with different components of the body fluids are contained.
The method according to claim 1,
The base on which the sheet is formed
Wherein the sample is formed of a material through which light is transmitted.
8. The method of claim 7,
The base
Wherein the sample is colored with a predetermined monochromatic color.
delete The method according to claim 1,
The conductive pattern
A second surface of the base opposite to the first surface of the base, and a portion of the first surface other than the sheet forming position.
A sample portion having a base on which a sheet is formed so as to be concave than the first surface so as to contain body fluids, a conductive pattern on which an electrode terminal is formed on the base, and an optobore coupled to the first surface of the base to expose the sheet;
A magnifying lens group for magnifying a body fluid to be applied to the sample portion, the magnifying lens group being inserted or ejected from the sample portion;
A camera for capturing an image of the body fluid enlarged by the magnifying lens group;
A light source unit for supplying light for photographing to the sample unit;
A controller for analyzing an image of the body fluid to generate an analysis result; And
And a switching circuit unit for sensing an insertion or ejection of the sample unit to supply an operation signal to operate at least one of the camera, the light source unit, and the control unit, or to supply power to the camera,
The conductive pattern may include:
Wherein the sample portion is separated from or coupled with the switching circuit portion for controlling the power source as the sample portion is removed from the inspection device.
12. The method of claim 11,
The opto-
Wherein the sheet is formed in a ring shape in which a hole is formed and is coupled to the sheet edge of the base so that the sheet is exposed by the hole,
And is formed of an absorbing material that absorbs liquid.
The method of claim 12, wherein
Wherein an opaque film is attached to the surface of the optobo to prevent transmission of liquid.
14. The method of claim 13,
The non-
And an obverse surface of the optobob is attached to a surface of the optobob such that a side surface of the optobob with the hole is exposed.
13. The method of claim 12,
The opto-
And an indicator for displaying a predetermined visibility result by reacting with body fluids.
16. The method of claim 15,
The opto-
And a plurality of indicators for reacting with different components of the body fluids.
17. The method according to claim 15 or 16,
The camera captures an image of the opbo-box reacted with the body fluid to generate an image,
Wherein the controller compares the visibility result of the optobo with a previously stored image to analyze the state of the body fluid.
12. The method of claim 11,
The base
Wherein the light-transmissive material is formed of a light-transmissive material through which light is transmitted.
19. The method of claim 18,
The base
Wherein the coloring agent is colored with a predetermined monochromatic color.
12. The method of claim 11,
Further comprising a switching circuit unit for sensing an insertion or ejection of the sample unit to supply an operation signal to operate at least one of the camera, the light source unit and the control unit, or to switch the power source to supply power. .
delete 12. The method of claim 11,
The conductive pattern
A second surface of the base opposite to the first surface of the base, and a portion of the first surface other than the sheet forming position.
12. The method of claim 11,
A seating portion for supporting or fixing the sample portion when the sample portion is inserted,
Wherein the seating portion is formed with a contact portion for electrically connecting the conductive pattern and the switching circuit when the sample portion is inserted, the contact portion being in electrical contact with the conductive pattern.
KR1020160155782A 2016-11-22 2016-11-22 Sampler for body fluid analysis device and body fluid analysis device using the same KR101920273B1 (en)

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KR102333043B1 (en) * 2019-09-02 2021-12-01 (주)인트인 Body fluid testing device
KR102288223B1 (en) * 2019-09-06 2021-08-10 (주)인트인 Chamber for inspecting body-fluid and body-fluid inspecting apparatus using the same
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