CN219142625U

CN219142625U - Portable colloidal gold reagent card analyzer

Info

Publication number: CN219142625U
Application number: CN202223371049.7U
Authority: CN
Inventors: 肖潇; 童坤; 黄磊; 邵长智
Original assignee: Nanjing Shenji Pharmaceutical Technology Co ltd
Current assignee: Nanjing Shenji Pharmaceutical Technology Co ltd
Priority date: 2022-12-15
Filing date: 2022-12-15
Publication date: 2023-06-06
Anticipated expiration: 2032-12-15

Abstract

The application relates to a portable colloidal gold reagent card analyzer, and relates to the field of colloidal gold reagent card analyzers. The light source is arranged in the shell, the detector is used for detecting a reflected light beam of the detection area of the reagent card, the light source is arranged in the shell, the detector is further arranged in the shell, the light source is arranged between the light source and the reagent card, the grating is further arranged between the detector and the reagent card, a first light hole aligned with the light source is formed in the grating, and a second light hole aligned with the detector is further formed in the grating. The application has the advantages of improving the detection precision of the analyzer on the detection result of the reagent card.

Description

Portable colloidal gold reagent card analyzer

Technical Field

The application relates to the field of colloidal gold reagent card analyzers, in particular to a portable colloidal gold reagent card analyzer.

Background

Colloidal gold immunochromatography is a rapid detection technology which has been developed in recent years, is an immunoassay method, and is a simple, rapid and sensitive analysis method which combines antigen-antibody reaction with a sensitive detection system.

The test of the colloidal gold reagent card is usually carried out by mainly relying on a visual method to judge the detection result, namely, the color depth of a detection line and a quality control line on the colloidal gold reagent card is observed by naked eyes, the detection line is a T line, the quality control line is a C line, and the visual method can only carry out qualitative judgment on the colloidal gold reagent card, namely, whether the immune function is achieved or not, but the antigen-antibody reaction degree is difficult to obtain according to the color depth of the detection line and the quality control line.

In order to improve the judgment accuracy of the detection result, an operator adds fluorescent substances in the detection area of the reagent card, after the detection result of the reagent card is displayed in the detection area, the operator irradiates the detection area through laser to excite the fluorescent substances in the detection area, and then the photoelectric cell receiver receives the light beam reflected by the excitation detection area, converts the light signal into an electric signal through the photoelectric cell receiver, and transmits the electric signal to a main board for data analysis. After the detection result of the reagent card is displayed in the detection area, the color of the CT line becomes dark, and the effect of reflecting laser light in the dark area is better. The laser irradiates from one end to the other end of the detection area of the reagent card in sequence, the intensity change of the light reflected by the detection area in the process is transmitted to the main board in the form of an electric signal through the photocell receiver, and the data of the reflected light of the C line and the T line are analyzed through the main board, so that a specific antigen-antibody reaction degree detection result is obtained.

Because the analysis of reagent card testing result relies on the fluorescent material reflection light beam in the reagent card testing area, when the light that laser emitter sent is weaker, can influence CT line reflection light beam's intensity for CT line is in the inaccurate data value that corresponds of mainboard, influences the judgement of this analyzer to the specific testing result of reagent card easily.

Disclosure of Invention

In order to improve the detection precision of the analyzer to the detection result of the reagent card, the application provides a portable colloidal gold reagent card analyzer.

The application provides a portable colloidal gold reagent card analyzer adopts following technical scheme:

the utility model provides a portable colloidal gold reagent card analysis appearance, includes the casing, offer the socket that is used for inserting the reagent card on the casing, be provided with in the casing and be used for shining the light source of reagent card detection area, still be provided with in the casing and be used for detecting the detector of reagent card detection area reflection light beam, still including set up in the plano-convex lens in the casing, plano-convex lens is located the light source with between the reagent card, plano-convex lens with still be provided with the grating between the reagent card, just the grating still is located the detector with between the reagent card, offer on the grating with first light trap of light source alignment, still offer on the grating with the second light trap of detector alignment.

Through adopting above-mentioned technical scheme, the light source sends laser beam, after the light beam is through plano-convex lens, make the light beam focus reduce, rethread grating gathers the light beam and obtains the facula size of specific size, excite the fluorescent material in the reagent card detection zone, the detector receives the light beam that excites reagent card reflection, and scan CT line on the reagent card and obtain detection data, increase the intensity that the light beam shines on the reagent card of excitation through plano-convex lens and grating, improve the detector receiving effect, the luminance enhancement when light beam CT line, the fluorescent material reflection of light intensity of detection zone CT line is strengthened, so that the detector is contrasted and is analyzed C line and T line data and obtain the testing result, and then the detection precision of this analysis instrument to reagent card testing result is improved. In addition, the device for detection is arranged in a small-sized shell, so that the size of the analyzer is reduced, and the portability of the analyzer is improved.

Optionally, a lampshade is arranged on the light source, and a through hole for the light source to penetrate through is arranged on the lampshade.

Through adopting above-mentioned technical scheme, set up the lamp shade in order to prevent the interference light source of other lights to play the guard effect to the light source.

Optionally, a mounting seat is arranged in the shell, a slot for the reagent card to be inserted is formed in the mounting seat, a notch of the slot is opposite to the socket, and a through groove is formed in one side of the mounting seat, facing the light source.

Through adopting above-mentioned technical scheme, the operator inserts the socket with the reagent card to in making the reagent card insert the slot, the light source can shine in the detection area of reagent card through logical groove, improves the grafting stability of reagent card in the casing, reduces reagent card and rocks, leads to the great condition of testing result error.

Optionally, a spring ball for abutting against the reagent card is fixedly connected to the mounting seat.

Through adopting above-mentioned technical scheme, the operator inserts the slot with the reagent card, and the spring ball supports tightly on the reagent card, restricts the condition that the reagent card pulled out the slot easily.

Optionally, the mount pad slides and set up in the casing, fixedly connected with is used for driving on the casing the drive assembly that the mount pad removed.

Through adopting above-mentioned technical scheme, the operator inserts the reagent card in the slot, then the operator rethread drive assembly drives the mount pad and removes a section distance for the facula of light source falls in the one end that reagent card detection area is close to the socket, then drive assembly drives the mount pad again and moves in opposite directions, makes the facula of light source remove to the other end from the one end of reagent card detection area, until the mount pad resets. The detector is capable of detecting the light beam reflected by the detection area of the reagent card and scanning the CT line on the actual card strip.

Optionally, the drive assembly including rotate connect in lead screw in the casing, just the axis direction of lead screw with the slip direction of mount pad is parallel, the thread bush is equipped with the nut on the lead screw, nut fixed connection in on the mount pad, fixedly connected with is used for driving in the casing lead screw pivoted driving motor.

Through adopting above-mentioned technical scheme, the operator starts driving motor and drives the lead screw and rotate, and then drives the axial displacement of nut along self to drive mount pad and reagent card synchronous motion.

Optionally, one end fixedly connected with that the mount pad kept away from slot notch is used for with reagent card butt contact switch, works as reagent card butt when contact switch, driving motor starts to drive the lead screw rotates and sets for the number of turns, and back rotation stops rotating after the same number of turns again.

Through adopting above-mentioned technical scheme, when reagent card butt contact switch, driving motor starts and drives the lead screw and rotate the setting number of turns, stop rotating after the same number of turns of reverse rotation again, and then drive reagent card one end of sliding and set for the distance, reverse removal to reset again.

Optionally, the caulking groove has been seted up on the cell wall of slot, the mount pad is at caulking groove internal inclination fixedly connected with elastic sheet, elastic sheet one end fixedly connected with slipmat, just slipmat compress tightly on the reagent card.

By adopting the technical scheme, the elastic sheet pushes the anti-slip pad to be abutted against the reagent card, so that the reagent card is fixed in the slot.

Optionally, the elastic sheet slope sets up, just the elastic sheet is kept away from the one end orientation of slot notch the reagent card slope, run through on the mount pad and be provided with the guide bar, the guide bar is used for the butt the elastic sheet, be provided with on the mount pad and be used for promoting the guide bar is kept away from the spring of elastic sheet.

Through adopting above-mentioned technical scheme, the operator presses the guide bar for the guide bar overcomes the elasticity effect of spring and supports tightly on the elastic sheet, makes the elastic plate drive the slipmat and keeps away from the reagent card, so that the operator pulls out the reagent card.

In summary, the present application includes at least one of the following beneficial technical effects:

1. setting a plano-convex lens to focus laser, increasing the brightness of laser beams, enhancing the reflection intensity of fluorescent substances on CT lines in a detection area, so that a detector can compare and analyze C line and T line data to obtain detection results, and further improving the detection precision of the analyzer on the detection results of the reagent card;

2. the operator inserts the reagent card into the slot, and the spring ball is supported tightly on the reagent card, restricts the condition that the reagent card is pulled out the slot easily.

Drawings

Fig. 1 is a schematic overall structure of an embodiment of the present application.

Fig. 2 is a schematic structural diagram of an embodiment of the present application for embodying a driving assembly.

Fig. 3 is an exploded view of an embodiment of the present application for embodying a spring ball.

Fig. 4 is a cross-sectional view of an embodiment of the present application for embodying a light source and detector.

Fig. 5 is an enlarged schematic view of the portion a in fig. 4.

Fig. 6 is an exploded view of an embodiment of the present application for embodying an elastic sheet.

Fig. 7 is an enlarged schematic view of the portion B in fig. 6.

Reference numerals illustrate: 1. a housing; 11. a mounting base; 12. a slot; 13. a through groove; 14. a reagent card; 15. a socket; 16. a mounting hole; 17. spring balls; 2. a mounting frame; 21. a light source; 22. a lamp shade; 23. a through hole; 24. a detector; 25. a main board; 26. a photocell receiver; 3. a grating; 31. a first light hole; 32. a second light hole; 33. a plano-convex lens; 34. a light filter; 4. a drive assembly; 41. a screw rod; 42. a nut; 43. a driving motor; 44. a contact switch; 5. a caulking groove; 51. an elastic sheet; 52. an anti-slip pad; 54. a guide rod; 55. a spring; 56. end plates.

Detailed Description

The present application is described in further detail below in conjunction with figures 1-7.

Example 1

The embodiment of the application discloses a portable colloidal gold reagent card analyzer. As shown in fig. 1 and 2, the portable colloidal gold reagent card analyzer comprises a housing 1, a cuboid plate-shaped mounting seat 11 is horizontally arranged in the housing 1, a slot 12 for inserting a reagent card 14 is formed in one end of the mounting seat 11 along the length direction of the mounting seat, and a through slot 13 communicated with the slot 12 is formed in the upper surface of the mounting seat 11. When the reagent card 14 is inserted into the slot 12 and the reagent card 14 abuts against the slot wall of the slot 12 far from the slot opening, the detection area of the reagent card 14 is located in the through slot 13. A socket 15 is provided in the housing and the socket 15 is aligned with the slot opening of the slot 12.

As shown in fig. 2 and 3, the mounting seat 11 is provided with a mounting hole 16 on the bottom wall of the slot 12, and a spring ball 17 is fixedly connected in the mounting hole 16, and the spring ball 17 is used for abutting against the lower surface of the reagent card 14.

As shown in fig. 4, a mounting frame 2 is fixedly connected to the inner wall of the housing 1, a light source 21 is mounted on the mounting frame 2, the light source 21 is located right above the detection area of the reagent card 14, the light source 21 is a laser emitter, and the laser emitter emits a light beam towards the detection area of the reagent card 14. The light source 21 is fixedly connected with a cylindrical lampshade 22 outside, and a through hole for the light source 21 to penetrate is formed in the lampshade 22, so that interference of other light rays is blocked through the lampshade 22.

The housing 1 is further provided with a detector 24, the detector 24 comprises a main board 25 and a photocell receiver 26, the photocell receiver 26 is fixedly connected to the mounting frame 2, and the photocell receiver 26 is obliquely arranged towards the detection area of the reagent card 14 and is used for receiving the light beam reflected by the detection area of the reagent card 14.

As shown in fig. 4 and 5, the grating 3 is horizontally and fixedly connected to the lower end surface of the mounting frame 2, and a first light hole 31 and a second light hole 32 are formed in the grating 3, the first light hole 31 is used for allowing a light beam emitted by the light source 21 to pass through, and the second light hole 32 is used for allowing a light beam reflected by the detection area of the reagent card 14 to pass through. The mounting frame 2 is fixedly connected with a plano-convex lens 33 between the first light-transmitting hole 31 and the light source 21, the plano-convex lens 33 gathers the light beams emitted by the light source 21, and then the light beams are gathered by the first light-transmitting hole 31 to obtain light spots with specific size, and the light spots irradiate the detection area of the reagent card 14 and excite fluorescent substances in the detection area. The mounting frame 2 is fixedly connected with a light filter 34 between the second light transmission hole 32 and the photocell receiver 26. After the detection area of the reagent card 14 reflects the light beam, a light spot with a specific size is formed through the second light transmission hole 32, the light spot passes through the optical filter 34 to obtain a light spot with a specific wavelength, and the light spot falls on the photocell receiver 26 to form a fixed signal and is transmitted to the main board 25.

The mounting seat 11 slides along the length direction of the mounting seat and is arranged on the inner bottom wall of the shell 1, and a driving assembly 4 for driving the mounting seat 11 to move is arranged on the inner bottom wall of the shell 1. The driving assembly 4 comprises a screw 41 rotatably connected to the inner bottom wall of the housing 1, and the axial direction of the screw 41 is parallel to the moving direction of the mounting seat 11. The screw rod 41 is sleeved with a nut 42 in a threaded manner, and the nut 42 is fixedly connected to the mounting seat 11 through a connecting rod. The inner bottom wall of the shell 1 is fixedly connected with a driving motor 43, an output shaft of the driving motor 43 is fixedly connected with the screw rod 41 in a coaxial mode, and a controller for controlling the driving motor 43 to be started and stopped is further arranged in the shell 1. The mounting frame 2 is fixedly connected with a contact switch 44 in the slot 12, and the contact switch 44 is positioned at one end of the slot 12 far away from the notch.

The implementation principle of the embodiment of the application is as follows: when the operator inserts the reagent card 14 and abuts against the contact switch 44, the light spot of the light source 21 falls outside the detection area of the reagent card 14, and the light spot is located at one end of the detection area of the reagent card 14 away from the socket 15. The contact switch 44 is triggered by abutting against the reagent card 14 and sends an electric signal to the main board 25, and the main board 25 controls the driving motor 43 to rotate for a set number of turns and then stop after reversely rotating for the same number of turns. In this process, the reagent card 14 moves in a direction away from the socket 15 until the light spot of the light source 21 falls on one end of the CT line of the reagent card 14 near the socket 15, and then moves reversely to abut against the initial position. In the process that the light spot of the light source 21 moves from one end of the CT line close to the socket 15 to one end of the CT line far away from the socket 15, the main board 25 analyzes and detects the reflected light in the detection area of the reagent card 14, and the detection result is obtained by comparing the fluorescence brightness of the C line and the T line.

Example 2

As shown in fig. 6 and 7, the difference between the present embodiment 2 and embodiment 1 is that the mounting seat 11 is provided with a caulking groove 5 on the wall of the slot 12, an elastic piece 51 is fixedly connected in the caulking groove 5, the elastic piece 51 is obliquely arranged, and one end of the elastic piece 51 facing the slot opening of the slot 12 is fixedly connected to the bottom wall of the caulking groove 5. The other end of the elastic piece 51 is fixedly connected with an anti-slip pad 52, the anti-slip pad 52 is used for abutting against the reagent card 14, and one end, close to the anti-slip pad 52, of the elastic piece 51 inclines outwards towards the caulking groove 5. The mounting seat 11 is provided with a guide groove which is communicated with the caulking groove 5, a guide rod 54 is arranged in the guide groove in a sliding way, the sliding direction of the guide rod 54 is parallel to the sliding direction of the mounting seat 11, and the guide rod 54 is used for pushing the elastic piece 51. Both ends of guide bar 54 all fixedly connected with end plate 56, limit guide bar 54 and break away from guide slot 53 through setting up end plate 56, the one end cover that guide bar 54 kept away from caulking groove 5 is equipped with spring 55, and spring 55 one end supports tightly on mount pad 11, and the other end of spring 55 supports tightly on corresponding end plate 56, and spring 55 promotes guide bar 54 and keeps away from elastic sheet 51.

After the operator inserts the reagent card 14 into the slot 12, the elastic sheet 51 presses the anti-slip pad 52 against the reagent card 14, and fixes the position of the reagent card 14. The operator presses the guide rod 54, so that the guide rod 54 pushes the elastic sheet 51 to drive the anti-slip pad 52 to separate from the reagent card 14, and the operator pulls the reagent card 14 out of the slot 12.

The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.

Claims

1. The utility model provides a portable colloidal gold reagent card analysis appearance, includes casing (1), offer on casing (1) and be used for inserting socket (15) of reagent card (14), be provided with in casing (1) and be used for shining reagent card (14) detection area's light source (21), still be provided with in casing (1) and be used for detecting reagent card (14) detection area reflection light beam's detector (24), its characterized in that: still including set up in plano-convex lens (33) in casing (1), plano-convex lens (33) are located light source (21) with between reagent card (14), plano-convex lens (33) with still be provided with grating (3) between reagent card (14), just grating (3) still are located detector (24) with between reagent card (14), set up on grating (3) with first light trap (31) of light source (21) alignment, set up on grating (3) with second light trap (32) of detector (24) alignment.

2. The portable colloidal gold reagent card analyzer according to claim 1, wherein: the light source (21) is provided with a lampshade (22), and the lampshade (22) is provided with a through hole for the light source (21) to penetrate through.

3. The portable colloidal gold reagent card analyzer according to claim 1, wherein: the novel reagent card is characterized in that an installation seat (11) is arranged in the shell (1), a slot (12) for inserting the reagent card (14) is formed in the installation seat (11), a notch of the slot (12) is opposite to the socket (15), and a through groove (13) is formed in one side, facing the light source (21), of the installation seat (11).

4. A portable colloidal gold reagent card analyzer according to claim 3, wherein: and a spring ball (17) used for propping against the reagent card (14) is fixedly connected to the mounting seat (11).

5. A portable colloidal gold reagent card analyzer according to claim 3, wherein: the mounting seat (11) is slidably arranged in the shell (1), and the shell (1) is fixedly connected with a driving assembly (4) for driving the mounting seat (11) to move.

6. The portable colloidal gold reagent card analyzer according to claim 5, wherein: the driving assembly (4) comprises a screw rod (41) which is rotationally connected to the inside of the shell (1), the axial direction of the screw rod (41) is parallel to the sliding direction of the mounting seat (11), a nut (42) is sleeved on the screw rod (41) in a threaded mode, the nut (42) is fixedly connected to the mounting seat (11), and a driving motor (43) used for driving the screw rod (41) to rotate is fixedly connected to the inside of the shell (1).

7. The portable colloidal gold reagent card analyzer according to claim 6, wherein: one end of the mounting seat (11) far away from the notch of the slot (12) is fixedly connected with a contact switch (44) which is used for being abutted with the reagent card (14), when the reagent card (14) is abutted with the contact switch (44), the driving motor (43) is started to drive the screw rod (41) to rotate for a set number of turns, and then the screw rod is reversely rotated for the same number of turns to stop rotating.

8. A portable colloidal gold reagent card analyzer according to claim 3, wherein: the slot wall of the slot (12) is provided with a caulking groove (5), the mounting seat (11) is fixedly connected with an elastic sheet (51) in the caulking groove (5) in an inclined mode, one end of the elastic sheet (51) is fixedly connected with an anti-slip pad (52), and the anti-slip pad (52) is tightly pressed on the reagent card (14).

9. The portable colloidal gold reagent card analyzer according to claim 8, wherein: the utility model discloses a reagent card, including slot (12) and reagent card (14), including mounting bracket (11), elastic piece (51) slope setting, just elastic piece (51) are kept away from the one end orientation of slot (12) notch is towards reagent card (14) slope, run through on mount bracket (11) and be provided with guide bar (54), guide bar (54) are used for the butt elastic piece (51), be provided with on mount bracket (11) and be used for promoting spring (55) that elastic piece (51) were kept away from to guide bar (54).