CN220490842U - Spliced immune chromogenic kit - Google Patents
Spliced immune chromogenic kit Download PDFInfo
- Publication number
- CN220490842U CN220490842U CN202321757031.2U CN202321757031U CN220490842U CN 220490842 U CN220490842 U CN 220490842U CN 202321757031 U CN202321757031 U CN 202321757031U CN 220490842 U CN220490842 U CN 220490842U
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- Prior art keywords
- kit
- spliced
- cavity
- liquid
- immune
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- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 27
- 239000007788 liquid Substances 0.000 claims abstract description 25
- 238000005406 washing Methods 0.000 claims abstract description 8
- 239000000463 material Substances 0.000 claims abstract description 4
- 238000011161 development Methods 0.000 claims description 16
- 230000014759 maintenance of location Effects 0.000 claims description 7
- 229920001971 elastomer Polymers 0.000 claims description 6
- 238000012744 immunostaining Methods 0.000 claims description 6
- 239000004917 carbon fiber Substances 0.000 claims description 3
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 claims description 3
- -1 polyethylene carbon Polymers 0.000 claims description 3
- 229920001821 foam rubber Polymers 0.000 claims description 2
- 238000002474 experimental method Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000011532 immunohistochemical staining Methods 0.000 description 4
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 230000003139 buffering effect Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000003018 immunoassay Methods 0.000 description 2
- 230000002055 immunohistochemical effect Effects 0.000 description 2
- 239000012089 stop solution Substances 0.000 description 2
- 206010027476 Metastases Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000012916 chromogenic reagent Substances 0.000 description 1
- 230000010485 coping Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000003748 differential diagnosis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 206010061289 metastatic neoplasm Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000010827 pathological analysis Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
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- Buffer Packaging (AREA)
Abstract
The utility model discloses a spliced immune chromogenic kit, which relates to the technical field of kits and comprises a kit body and a kit cover, wherein a cavity is formed in the kit cover, a cavity is formed in the kit body, an article placing component is arranged in the cavity, and washing liquid, chromogenic liquid, stop liquid and a reagent tube are placed in the article placing component. According to the kit, the technical problems that the related kit cannot cope with various experimental environments and is not fully protected are solved, the problem of small application range in the traditional kit is solved through the mutual matching among the washing liquid, the developing liquid and the stop liquid reagent tubes arranged in the kit body, and the safety of the reagent in the kit body is ensured through various cushioning devices in the article placement assembly by arranging the shape and the materials of the box cover.
Description
Technical Field
The utility model relates to the technical field of kits, in particular to a spliced immune chromogenic kit.
Background
Immunohistochemical staining is called immunohistochemical for short, and is a research of locating, qualitatively and quantitatively determining antigens in human tissue cells by applying the principle of specific binding of antigens and antibodies and making a color developing agent marked with the antibodies develop through chemical reaction. Current immunohistochemical staining includes immunofluorescent cytochemistry techniques, immunoenzymatic cytochemistry techniques, and immunocolloidal gold techniques, among others. Immunohistochemical staining can be used for diagnosis and differential diagnosis of malignant tumors, determination of primary sites of metastatic tumors or further pathological typing of tumors, finding of tiny metastasis and the like. Immunohistochemical examination also provides a choice of therapeutic protocols for the clinic, so immunohistochemical staining greatly improves the accuracy of pathological diagnosis. Corresponding chromogenic reagents are required in the course of performing the immunological chromogenic procedure.
The prior patent (publication number: CN 106540756A) discloses a kit, which comprises a kit body, a kit cover, a fixed seat and a reagent tube; the box body is movably connected with the box cover, a buckle is arranged on the box cover, a lug matched with the buckle is arranged on the side wall of the box body, a first groove is formed in the edge of the box cover, and a protrusion matched with the first groove is arranged at the top of the box body; the fixed seat is positioned in the box body, and a plurality of fixed holes are formed in the fixed seat; the reagent tube is placed in the fixing hole.
However, the above design-in practical applications-has some drawbacks: if the reagent box is limited in reagent type, most experimental environments cannot be dealt with, and the protection of internal reagents is not comprehensive enough, and after slight collision, reagent pipes in the box are easy to collide to cause damage.
Disclosure of Invention
The utility model provides a spliced immune chromogenic kit, which solves the technical problems that the kit cannot cope with various experimental environments and is not fully protected.
In order to solve the technical problems, the spliced immune chromogenic kit provided by the utility model comprises: the box comprises a box body and a box cover, wherein a cavity is formed in the box cover, a cavity is formed in the box body, an article placing component is arranged in the cavity, and washing liquid, color development liquid, termination liquid and a reagent tube are placed in the article placing component.
Preferably, the article placement assembly comprises: the clamping plate corresponding to the upper end in the box body, an L-shaped bracket connected to the lower bottom surface of the clamping plate, a retention plate fixedly connected to the middle part of the L-shaped bracket, and a foam-rubber cushion placed at the upper end of the lower half part of the L-shaped bracket.
Preferably, the number of the L-shaped brackets is four and the L-shaped brackets are fixedly connected with each other.
Preferably, three kinds of annular holes are formed in the surface of the retention plate, namely a middle annular hole, a small annular hole and a large annular hole, and rubber rings are arranged on the inner walls of the three kinds of annular holes.
Preferably, the number of reagent tubes is nine.
Preferably, the material of the box cover is high-elasticity polyethylene carbon fiber.
Preferably, a pull rod is arranged in the middle of the side face of the box body.
Preferably, a holding rod is arranged at the middle part of the upper surface of the box cover.
Compared with the related art, the spliced immune chromogenic kit provided by the utility model has the following components
The beneficial effects are that:
1. in the utility model, the problem of small application range in the kit is solved by the mutual matching among the washing liquid, the developing liquid and the stop solution reagent pipes arranged in the kit body.
2. According to the utility model, the shape and the material of the box cover are arranged, and the safety of the reagent in the spliced immune color development kit is ensured by arranging the sponge cushion at the bottom of the article placement component, the retention plate at the middle part, the middle ring hole, the small ring hole and the large ring hole on the surface of the retention plate and arranging the rubber rings on the inner walls of the middle ring hole, the small ring hole and the large ring hole.
Drawings
FIG. 1 is a schematic diagram showing the overall structure of a split-type immunoassay kit;
FIG. 2 is a schematic diagram showing the overall structure of a closed split-type immunoassay kit;
FIG. 3 is a schematic diagram of the internal structure of a spliced immune color development kit;
fig. 4 is a schematic structural diagram of an article placement component of a spliced immune color development kit:
fig. 5 is a schematic structural diagram of a cartridge body of a spliced immunostaining kit.
Reference numerals in the drawings: 1. a case body; 2. a box cover; 3. a clamping plate; 4. an L-shaped bracket; 5. a retention plate; 6. a sponge cushion; 7. a washing liquid; 8. developing solution; 9. a stop solution; 10. a reagent tube; 11. a cavity; 12. a middle ring hole; 13. a small annular hole; 14. a large annular hole; 15. a pull rod; 16. a grip; 17. a cavity; 18. a rubber ring.
Detailed Description
Embodiments of the present utility model are described in detail below.
Examples of the embodiments are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functionality throughout. The embodiments described below by referring to the drawings are exemplary only for explaining the present utility model and are not to be construed as limiting the present utility model.
Referring to fig. 1-5, a tiled immunostaining kit comprising: the box body 1 and the box cover 2 are characterized in that a cavity 17 is formed in the box cover 2, the volume of the cavity 17 is slightly smaller than that of the box body 1, a pull rod 15 is arranged at the middle part of the side face of the box body 1, the pull rod 15 can enable the box body 1 to be pulled out of the box cover 2 more conveniently, the box cover 2 is made of high-elasticity polyethylene carbon fiber, the box body 1 can be placed in the cavity 17 even if the volume of the cavity 17 formed in the box cover 2 is slightly smaller than that of the box body 1, the wrapping performance is better, the protection performance can be guaranteed, a holding rod 16 is arranged at the middle part of the upper surface of the box cover 2, the box body is more convenient to carry, a cavity 11 is formed in the box body 1, an article placing component is arranged in the cavity 11, the volume of the cavity 11 corresponds to the volume of the article placing component, and the corresponding volume enables the article placing component not to shake in the cavity 11.
On the basis of the scheme, washing liquid 7, color development liquid 8, termination liquid 9 and reagent pipes 10 are placed in the article placement component, the washing liquid 7, the color development liquid 8 and the termination liquid 9 can carry out multiple experiments on the same instrument, the used instrument is not damaged too much, the number of the reagent pipes 10 is nine, the nine reagent pipes 10 can well accommodate samples required by partial experiments, and the article placement component comprises: the cardboard 3 that corresponds with the inside upper end of box body 1, the connection that agrees with each other make the structure more firm, connect the L shape support 4 of bottom surface under cardboard 3, and the quantity of L shape support 4 is four and mutual fixed connection, and the supporting structure of article placement module has been constituteed to mutual fixed connection's L shape support 4, has ensured article placement module's stability.
On the basis of the scheme, the fixing plate 5 is fixedly connected to the middle part of the L-shaped support 4, the fixing plate 5 enables reagents not to collide with each other in the article placing component to be damaged, three annular holes are formed in the surface of the fixing plate 5, namely, a middle annular hole 12, a small annular hole 13 and a large annular hole 14, different reagents can be placed in different reserves through the three annular holes, more fitting experiments are required, rubber rings 18 are arranged on the inner walls of the three annular holes, the reagents placed in the three annular holes cannot collide with the fixing plate 5 due to the existence of the rubber rings 18, a certain buffering function is provided, safety is improved, a spongy cushion 6 is placed at the upper end of the lower half part of the L-shaped support 4, and the bottom of the reagents placed in the article placing component is not directly contacted with the box body 1 through the spongy cushion 6, so that a buffering protection effect is achieved.
Working principle:
when a color development experiment is required to be carried out on an article:
the holding rod 16 is held by one hand, then the pull rod 15 is pulled by the other hand, the box body 1 can shake due to the action of force during the process, but the reagent does not need to be considered too much in the article placing component, the article placing component is provided with a plurality of cushioning protection devices, so long as the box body 1 is not subjected to severe impact, the safety of the reagent in the box body 1 can be ensured, the reagent in the box body 1 can be used for carrying out a color development experiment on the article to be tested by using the color development liquid 8 after the box body 1 is pulled out, the reaction can be stopped by only placing the stop liquid 9 when the experiment is required to be stopped after the experimental result is obtained, if the experiment is required to be carried out again on another article, the color development experiment can be carried out again by using the color development liquid 8 after the liquid is disappeared in the experimental instrument, and a plurality of experimental samples can be placed in the reagent tube 10 with nine quantities, and the articles can be used for coping with most of the color development experiments.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. A tiled immunochromogenic kit comprising: the novel color box is characterized in that a cavity (17) is formed in the box cover (2), a cavity (11) is formed in the box body (1), an article placing component is arranged in the cavity (11), and a washing liquid (7), a color development liquid (8), a termination liquid (9) and a reagent tube (10) are arranged in the article placing component.
2. The spliced immune color development kit according to claim 1, wherein the article placement component further comprises a clamping plate (3) corresponding to the upper end inside the box body (1), an L-shaped bracket (4) connected to the lower bottom surface of the clamping plate (3), a retention plate (5) fixedly connected to the middle part of the L-shaped bracket (4), and a foam-rubber cushion (6) placed at the upper end of the lower half part of the L-shaped bracket (4).
3. A spliced immunostaining kit as in claim 2, wherein the number of L-shaped brackets (4) is four and fixedly connected to each other.
4. The spliced immune color development kit according to claim 2, wherein three annular holes are formed in the surface of the retention plate (5), namely a middle annular hole (12), a small annular hole (13) and a large annular hole (14), and rubber rings (18) are arranged on the inner walls of the three annular holes.
5. The spliced immunostaining kit as claimed in claim 4, wherein the number of reagent tubes (10) is nine.
6. The spliced immune color development kit according to claim 5, wherein the material of the box cover (2) is high-elasticity polyethylene carbon fiber.
7. The spliced immunostaining kit according to claim 6, wherein a pull rod (15) is mounted at the middle part of the side face of the kit body (1).
8. The spliced immunostaining kit according to claim 7, wherein a holding rod (16) is arranged in the middle of the upper surface of the box cover (2).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202321757031.2U CN220490842U (en) | 2023-07-06 | 2023-07-06 | Spliced immune chromogenic kit |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202321757031.2U CN220490842U (en) | 2023-07-06 | 2023-07-06 | Spliced immune chromogenic kit |
Publications (1)
Publication Number | Publication Date |
---|---|
CN220490842U true CN220490842U (en) | 2024-02-13 |
Family
ID=89829011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202321757031.2U Active CN220490842U (en) | 2023-07-06 | 2023-07-06 | Spliced immune chromogenic kit |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN220490842U (en) |
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2023
- 2023-07-06 CN CN202321757031.2U patent/CN220490842U/en active Active
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