CN220194900U - Body fluid sample collection, storage and detection integrated device - Google Patents

Abstract

The utility model discloses a body fluid sample collecting, storing and detecting integrated device. The device comprises a sample collection lysis assembly, a stopper and a detection assembly. The sample collection and lysis assembly includes a sample collection tube and a lysis tube. The detection assembly comprises a reagent strip and a detection tube. The limiter is arranged between the connecting parts of the detection tube and the sample collecting tube and can be detached; according to the utility model, the limiter is inserted between the sample collecting pipe and the detection pipe which are in threaded connection, so that the relative positions of the sample collecting pipe and the cracking pipe in the detection pipe are kept stable in the processes of storing, transporting and adding sample liquid, and the sealing film at the bottom of the cracking pipe is prevented from being pierced, so that the reliability of the utility model is ensured. According to the utility model, after the limiter is pulled out, the sealing film can be pierced by only rotating the sample collecting pipe, so that the detection is realized, and the operation is very convenient.

Description

Body fluid sample collection, storage and detection integrated device

Technical Field

The utility model belongs to the technical field of liquid sample detection, and particularly relates to a body fluid sample collection, storage and detection integrated device.

Background

One type of test that exists in hospital testing is to take a sample of a liquid from a patient by sampling a swab or swab into a test tube. When a sampling swab is placed into the oral cavity or the nasal cavity for sampling, it is often difficult for medical staff to observe the collection condition of a liquid sample on the swab, so that the medical staff needs to wait for a long time. After the sampling is finished, the sampling swab or the cotton swab enters the clinical laboratory, and then the clinical laboratory needs to manually inject reagents and stir the reagents to treat endocrine matters in the sampling swab or the cotton swab. The process is complicated, and the examining physician not only consumes a lot of time, but also introduces human error and specimen pollution.

In the prior art, there are test tubes in which reagents for detecting a liquid sample are stored. But during opening of the test tube cap of the test tube and placing the swab containing the liquid sample into the test tube, the reagents in the test tube will be exposed to air. The placement of the swab tends to carry in the impurities present in the air. Part of test tubes are provided with films in the tubes to prevent impurities in the air from being mixed into the reagent, but the films can also block the contact between the swab and the reagent, so that the medical staff is difficult to obtain the required detection liquid.

Disclosure of Invention

The utility model aims to provide a body fluid sample collecting, storing and detecting integrated device.

The utility model relates to a body fluid sample collecting, storing and detecting integrated device which comprises a sample collecting and splitting assembly, a limiter and a detecting assembly. The sample collection and pyrolysis assembly comprises a sample collection tube and a pyrolysis tube. And a cover body is connected to the top opening of the sample collecting pipe. The outer side surface of the sample collecting pipe is provided with a connecting part. The cracking tube is sleeved outside the sample collecting tube. An opening is formed in the bottom of the sample collecting tube. The bottom of the cracking tube is provided with a liquid outlet. The liquid outlet is provided with a sealing film. The bottom of the sample collecting pipe is provided with a membrane rupture structure aligned with the sealing membrane.

The detection component comprises a reagent strip and a detection tube. The reagent strip is arranged on the inner side wall of the detection tube. The cracking tube is arranged in the detection tube. The connecting part of the sample collecting pipe is connected with the opening of the detection pipe, and the relative position can be adjusted in the axial direction.

The limiter is arranged between the connecting parts of the detection tube and the sample collecting tube and can be detached; and in a state that the limiter is not detached, the limiter limits the axial relative position of the sample collecting pipe and the detection pipe, so that a membrane breaking structure at the bottom of the sample collecting pipe is kept at a distance from a sealing membrane at the bottom end of the cracking pipe. Under the state that the limiter is detached, the axial position of the sample collecting pipe can be adjusted relative to the detection pipe, so that the membrane breaking structure at the bottom of the sample collecting pipe pierces the sealing membrane at the bottom end of the cracking pipe.

Preferably, in a state that the stopper is not detached, a locking structure for locking relative movement in the circumferential direction is formed between the stopper and the detection tube, and between the stopper and the sample collection tube.

Preferably, the bottom end of the sample collection tube is integrally formed with a sample extraction tube. The inner cavity of the sample eduction tube is communicated with the inner cavity of the sample collecting tube. The bottom of the sample eduction tube is provided with a chamfer surface which is used as a rupture membrane structure.

Preferably, the top of the outer side surface of the detection tube is provided with a first annular flange 4-3-1; the first annular flange 4-3-1 is aligned with the bottom edge of the connection portion of the sample collection tube. In the initial state, the limiter is arranged between the first annular flange 4-3-1 and the connecting part of the sample collecting pipe; the opposite side edges of the limiter are respectively contacted with the first annular flange 4-3-1 and the sample collecting pipe; the rupture membrane structure at the bottom of the sample collecting pipe and the sealing membrane of the cracking pipe are arranged at intervals, and the interval is smaller than the width of the circular arc limiting part.

Preferably, the connecting part and the first annular flange are provided with limit lugs; the limiter is provided with a clamping groove. Under the state that the limiter is not disassembled, the limiting convex blocks on the connecting part and the first annular flange are clamped into the clamping grooves on the limiter, so that the detection tube and the sample collecting tube cannot rotate relatively before the limiter is disassembled.

Preferably, the limiter comprises an arc limiting part, a holding part arranged at the middle position of the outer side surface of the arc limiting part, and two mounting guide parts respectively arranged at two ends of the arc limiting part. The arc limiting part is made of elastic material and is in an excellent arc shape; the two installation guide parts are gradually far away from each other from inside to outside.

Preferably, the top of the detection tube is provided with a second external thread. The first annular flange 4-3-1 is lower than the second external thread. The arc limiting part of the limiter is sleeved outside the second external thread. The connecting part of the sample collecting pipe is annular, and the inner side of the connecting part is provided with a second internal thread. The second external thread is matched with the second internal thread in shape.

Preferably, the top of the outer side surface of the cracking tube is integrally formed with a second annular flange 2-3-1. The second annular flange 2-3-1 is in contact with the rim of the top opening of the test tube, forming an axial location.

Preferably, the bottom surface of the inner cavity of the sample collecting tube and the bottom surface of the inner cavity of the cracking tube are both funnel-shaped and provided with a hydrophobic coating.

Preferably, the body fluid sample collection, storage and detection integrated device further comprises a collector. The collector comprises a collecting rod, a sampling progress indicating element and a sample absorber. The inner end of the collecting rod is fixed with the inner center of the cover body. The outer end of the acquisition rod is fixed with a sample absorber. The collecting rod is in a transparent tubular shape with an open outer end. The sampling progress indicating element is rectangular, and installs in the inner chamber of collection pole. The sampling progress indicating element is in contact with the sample absorber.

Preferably, the sample absorber is provided with a central hole. The outer end of the sampling progress indicating element extends out of the inner cavity of the acquisition rod and extends into the central hole of the sample absorber.

Preferably, the value range of the length l of the part of the sampling progress indicating element extending into the sample absorber is 0.1 t-0.2 t; t is the length of the sample absorber central hole.

Preferably, the cover body is provided with a first internal thread; the top of the sample collection tube is provided with first external threads. The first internal thread is matched with the shape of the first external thread.

Preferably, the outer end of the collection rod is provided with a suction head mounting portion. The sample absorber is coaxially fixed to the tip mounting portion. The suction head installation part is provided with a second sealing ring for sealing the suction head installation part and the inner side wall of the sample collecting pipe.

Preferably, the sample absorber is bonded and fixed to the outer end surface of the tip attachment portion. An annular groove is arranged on the outer end face of the suction head installation part. The annular groove divides the outer end face of the suction head mounting part into a central boss and an annular flange which surrounds the outer side of the central boss at intervals; the opening of the inner cavity of the collecting rod is positioned at the center of the center boss.

Preferably, a first sealing ring for sealing the top opening of the cover body and the sample collecting pipe is arranged in the cover body.

Preferably, a third sealing ring for sealing between the outer side surface of the sample collecting pipe and the inner side surface of the cracking pipe is arranged at the bottom of the outer side surface of the sample collecting pipe.

Preferably, the side wall of the cracking tube is provided with a gas guide through hole; the axial distance between the air guide through hole and the sealing film is equal to the distance between the third sealing ring and the outer end of the sample eduction tube.

The utility model has the beneficial effects that:

1. according to the utility model, the limiter is inserted between the sample collecting pipe and the detection pipe which are in threaded connection, so that the relative positions of the sample collecting pipe and the cracking pipe in the detection pipe are kept stable in the processes of storing, transporting and adding sample liquid, and the sealing film at the bottom of the cracking pipe is prevented from being pierced, so that the reliability of the utility model is ensured. According to the utility model, after the limiter is pulled out, the sealing film can be pierced by only rotating the sample collecting pipe, so that the detection is realized, and the operation is very convenient.

2. According to the utility model, the lock catch for circumferential locking is arranged between the sample collecting pipe and the limiter and between the detection pipe and the limiter, so that the sample collecting pipe cannot rotate before the limiter is pulled out, and the sample collecting pipe is prevented from being driven to rotate together when the cover body is rotated.

3. According to the utility model, the sealing rings are arranged between the end part of the collecting rod and the inner side surface of the sample collecting pipe and between the outer side surface and the cracking pipe, so that the sample liquid is prevented from flowing upwards in the sample collecting pipe or the cracking pipe in the process of extruding the liquid sample in the sample absorber and after the sealing film is pierced, the liquid sample is promoted to flow downwards rapidly in a pressure increasing mode, and the liquid sample is prevented from being detained in the sample collecting pipe or the cracking pipe due to air pressure balance.

4. The utility model sets the collection rod as a hollow transparent structure, and puts a strip-shaped sampling progress indicating element into the collection rod; the elongated structure of the sampling progress indicating element can facilitate the user to observe the color change thereof, thereby indicating the sufficiency of sample collection more clearly and accurately.

Drawings

FIG. 1 is a schematic diagram of the overall structure of the present utility model;

FIG. 2 is a schematic view of the structure of the present utility model in a state of taking out the collector;

FIG. 3 is a schematic cross-sectional view of the present utility model;

FIG. 4 is an exploded view of the collector of the present utility model;

FIG. 5 is a schematic cross-sectional view of a harvester according to the utility model;

FIG. 6 is a schematic diagram of a collector according to the present utility model;

FIG. 7 is a schematic view showing the structure of a suction head mounting portion in the present utility model;

FIG. 8 is an exploded view of the sample collection lysis assembly and stopper of the present utility model;

FIG. 9 is a schematic view of a sample collection tube according to the present utility model;

FIG. 10 is a schematic illustration of the mating of a sample collection tube with a lysis tube in accordance with the present utility model;

FIG. 11 is a schematic view of a stopper according to the present utility model;

FIG. 12 is an exploded view of the detection assembly of the present utility model.

Fig. 13 is a schematic diagram of the operation of the present utility model.

Reference numerals: 1. a collector; 1-1, a sampling cover; 1-2, a first sealing ring; 1-3, collecting a rod; 1-4, a second sealing ring; 1-5, a sampling progress indicating element; 1-6, sample absorber; 1-3-1, a suction head mounting part; 1-3-2, an annular groove; 2. a sample collection lysis assembly; 2-1, collecting a sample tube; 2-1-1, a connecting part; 2-1-2, a sample eduction tube; 2-2, a third sealing ring; 2-3, cracking tube; 2-3-1, a second annular flange; 2-3-2, air guide through holes; 3. a limiter; 3-1, an arc limiting part; 3-2, a holding part; 3-3, installing a guide part; 4. a detection assembly; 4-1, a reagent strip clamping groove; 4-2, reagent strips; 4-3, detecting tube; 4-3-1, a first annular flange; 5. a limit bump; 6. a clamping groove.

Detailed Description

The utility model is further described below with reference to the accompanying drawings.

An integrated device for collecting, storing and detecting body fluid samples as shown in fig. 1, 2 and 3 comprises a collector 1, a sample collecting and cracking component 2, a limiter 3 and a detection component 4. The body portion of the sample collection lysis assembly 2 is disposed within the detection assembly 4. The collector 1 is able to extend into the sample collection lysis assembly 2.

As shown in fig. 4, 5, 6 and 7, the collector 1 includes a sampling cap 1-1, a first sealing ring 1-2, a collection rod 1-3, a second sealing ring 1-4, a sampling progress indicating member 1-5 and a sample absorber 1-6. The circumference surface of the sampling cover 1-1 is provided with a concave-convex anti-slip structure, which is helpful for improving the anti-slip effect of the sampling cover. A first internal thread is provided in the sampling cap 1-1. A first sealing ring 1-2 is mounted within the sampling cap 1-1 for sealing between the collector 1 and the sample collection lysis assembly 2. The inner end of the acquisition rod 1-3 is fixed with the inner center of the sampling cover 1-1. The cover body and the collecting rod are jogged and fixed through a mortise structure.

The outer end of the acquisition rod 1-3 is fixed with a sample absorber 1-6. The outer end of the collecting rod 1-3 is integrally formed with a suction head mounting part 1-3-1. The sample absorber 1-6 is fixed coaxially with the tip mounting portion 1-3-1. The sample absorbers 1 to 6 are made of sponge or other materials capable of adsorbing a liquid sample. The second seal ring 1-4 is mounted on the outer circumferential surface of the suction head mounting portion 1-3-1. The second sealing ring 1-4 is embedded in an annular groove on the outer circumferential surface of the suction head mounting part 1-3-1. The second sealing ring 1-4 prevents the sample from flowing upwards when the sample is extruded into the sample collecting pipe, so that the sample loss is reduced.

The collecting rod 1-3 is in a hollow tubular structure with an open outer end. The sample absorber 1-6 is provided with a central hole which is communicated with the inner cavity of the acquisition rod 1-3. The sampling progress indicating element 1-5 is in a strip shape and is arranged in the inner cavity of the acquisition rod 1-3. The outer end of the sampling progress indicating element 1-5 extends out of the inner cavity of the acquisition rod 1-3 and into the inner end of the central hole of the sample absorber 1-6. The value range of the length l of the part of the sampling progress indicating element 1-5 extending into the sample absorber 1-6 is 0.1 t-0.2 t; t is the length of the central hole of the sample absorber 1-6.

In some embodiments, the sample absorber 1-6 is adhesively secured to the outer end surface of the tip mounting portion 1-3-1. The outer end surface of the suction head mounting part 1-3-1 is provided with an annular groove 1-3-2. The annular groove 1-3-2 divides the outer end face of the suction head mounting part 1-3-1 into a central boss and an annular flange which surrounds the outer side of the central boss at intervals; the outer end opening of the inner cavity of the acquisition rod 1-3 is positioned at the center of the center boss. The sample absorber 1-6 stretches into the annular groove 1-3-2 through deformation and is bonded with the inner side wall of the annular groove 1-3-2; the annular recess 1-3-2 can function to contain adhesive and help prevent the adhesive from flowing into and clogging the inner lumen of the collection rod.

The sampling progress indicating element 1-5 will change color when it is contacted with saliva, thereby indicating whether a sufficient amount of saliva is collected during the sampling process. The acquisition rod 1-3 is made of a transparent material so as to observe the color change of the sampling progress indicating element 1-5.

In some embodiments, the sampling progress indicating element 1-5 includes a strip-shaped substrate, and a color-changing coating disposed on an outer surface of the strip-shaped substrate. The color-changing coating is made of a material which becomes transparent when meeting water; the color-changing coating layer has a color in an initial state different from the surface color of the strip-shaped substrate. When the liquid sample wets the surface of the sampling progress indicating element 1-5, the color-changing coating becomes transparent, so that the color of the strip-shaped substrate appears.

In some embodiments, the sampling progress indicating element 1-5 comprises a bibulous paper strip, and a colored pigment disposed on an outer surface of the bibulous paper strip. The colored pigment is coated or sprayed on the water-absorbing paper strip. When the liquid sample infiltrates the surface of the sampling progress indicating element 1-5, the water absorbing paper strip absorbs the liquid sample, and pigment chromatography phenomenon occurs, so that indication is realized.

As shown in fig. 8, 9 and 10, the sample collection and lysis assembly 2 includes a sample collection tube 2-1, a third seal ring 2-2, and a lysis tube 2-3. The top opening of the outer side surface of the sample collecting pipe 2-1 is provided with a first external thread for connecting the collector 1; the top of the outer side surface of the sample collecting tube 2-1 is integrally formed with a connecting part 2-1-1. The connecting portion 2-1-1 is lower than the first external thread. The connecting portion 2-1-1 in the shape of a circular ring is circumferentially spaced around the outside of the main body portion of the sample collection tube 2-1. The inner side surface of the connecting part 2-1-1 is provided with a second internal thread for connecting the detecting assembly 4. When the connection part 2-1-1 is connected to the detection tube 4-3 in the detection assembly, the main body part of the sample collection tube 2-1 can be extended into the inside of the detection tube 4-3.

The bottom end of the sample collection tube 2-1 is integrally formed with a sample eduction tube 2-1-2. The inner cavity of the sample eduction tube 2-1-2 is communicated with the inner cavity of the sample collecting tube 2-1. The cracking tube 2-3 is sleeved outside the sample collecting tube 2-1. A liquid outlet is arranged at the bottom end of the cracking tube 2-3. The liquid outlet is provided with a sealing film. The bottom ends of the sample introduction tubes 2-1-2 are aligned with the sealing film. The bottom of the sample eduction tube 2-1-2 is provided with a chamfer surface, so that the bottom of the sample eduction tube 2-1-2 is sharp and can pierce the sealing film.

In some embodiments, the sealing membrane may be replaced with other frangible material, with a thin bottom thickness that allows the sharp bottom end of the sample delivery tube 2-1-2 to be pierced.

The lysis tube 2-3 is fixed in the detection assembly 4, while the sample collection tube 2-1 is axially movable relative to the detection assembly 4; thus, the sample collection tube 2-1 can pierce the sealing membrane at the bottom end of the lysis tube 2-3 by moving up and down, so that the mixed liquid of the liquid sample and the lysis solution flows into the detection assembly 4. The third sealing ring 2-2 is arranged at the bottom of the outer side surface of the sample collecting pipe 2-1; the third sealing ring 2-2 is embedded in an annular groove on the outer side surface of the sample collecting tube 2-1.

The first sealing ring 1-2 is used for sealing between the top opening of the sample collecting tube 2-1 and the sampling cover 1-1. The second seal ring 1-4 is used for sealing between the inner side surface of the sample collection tube 2-1 and the outer circumferential surface of the suction head mounting portion 1-3-1. The third sealing ring 2-2 is used for sealing between the outer side surface of the sample collecting tube 2-1 and the inner side surface of the cracking tube 2-3.

The side wall of the cracking tube 2-3 is provided with an air guide through hole 2-3-2; the axial distance between the air guide through hole 2-3-2 and the sealing film is equal to the distance between the third sealing ring 2-2 and the outer end of the sample eduction tube 2-1-2; therefore, when the sample lead-out tube 2-1-2 at the bottom end of the sample collection tube 2-1 contacts with the sealing film at the bottom end of the cracking tube 2-3, the air guide through hole 2-3-2 is flush with the third sealing ring 2-2. The air guide through hole 2-3-2 can keep the pressure in the cracking tube 2-3 stable before the sealing film is punctured, so that the sample eduction tube 2-1-2 can be ensured to move downwards smoothly.

In some embodiments, the bottom surface of the inner cavity of the sample collection tube 2-1 and the bottom surface of the inner cavity of the lysis tube 2-3 are both funnel-shaped and provided with a hydrophobic coating, so that liquid samples can be prevented from remaining in the sample collection tube 2-1 and the lysis tube 2-3.

As shown in FIG. 11, the test assembly 4 includes a mounting bracket 4-1, a reagent strip 4-2, and a test tube 4-3. The cracking tube 2-3 is arranged in the detecting tube 4-3 and forms axial positioning. The specific forming mode of the axial positioning is as follows: the top of the outer side surface of the cracking tube 2-3 is integrally formed with a second annular flange 2-3-1. The second annular flange 2-3-1 contacts the edge of the top opening of the test tube 4-3 to form an axial positioning. In addition, in some embodiments, the lysis tube 2-3 may also be directly secured with the detection tube 4-3. The cylindrical mounting bracket 4-1 is fixed in the inner cavity of the detection tube 4-3. The plurality of reagent strips 4-2 are respectively fixed in a plurality of clamping grooves in the mounting bracket 4-1. Each reagent strip 4-2 surrounds the circumference of the lysis tube 2-3. The draw-in groove is the airtight cavity of bottom open-ended, and it can prevent that capillary phenomenon from leading to reagent strip chromatography to be unusual.

The top of the outer side of the detection tube 4-3 is provided with a first annular flange 4-3-1 and a second internal thread for connecting to the connection 2-1-1 on the sample collection tube 2-1. The first annular flange 4-3-1 is located at the bottom of the second external thread. The first annular flange 4-3-1 serves to provide axial positioning of the connection 2-1-1 of the sample collection tube 2-1.

In some embodiments, the bottom surface of the inner cavity of the detecting tube 4-3 is in a conical structure with a high middle and a low periphery, so that the liquid sample can be gathered at the edge of the bottom surface of the inner cavity of the detecting tube and fully contacted with the reagent strip, and detection is realized.

In some embodiments, a plurality of convex lenses made of plastic are arranged on the outer side surface of the detection tube; the convex lenses are aligned with the result display areas of the reagent strips, and the detection results can be amplified and displayed by utilizing the convex lens amplification principle.

In some embodiments, twelve clamping grooves are formed in the mounting bracket 4-1, and corresponding twelve reagent strips can detect 12 different objects (such as medicines or drugs) at the same time, so that single-channel high-flux liquid sample detection is realized.

As shown in fig. 10, the stopper 3 includes an arc stopper portion 3-1, a grip portion 3-2 provided at a middle position of an outer side surface of the arc stopper portion 3-1, and two installation guide portions 3-3 provided at both ends of the arc stopper portion 3-1, respectively. The circular arc limiting part 3-1 is made of elastic materials and is in an excellent circular arc shape (namely, the circular arc with the central angle larger than 180 degrees); the inner diameter of the circular arc limiting part 3-1 is equal to the outer diameter of the second external thread on the detecting tube 4-3. The two installation guide parts 3-3 are gradually far away from each other from inside to outside, and the arc limiting parts 3-1 can be guided to deform at the second external thread of the detection tube 4-3 inserted in the limiter 3.

In an initial state, the limiter 3 is sleeved on the detection tube 4-3 and is positioned between the first annular flange 4-3-1 and the connecting part 2-1-1 of the sample collecting tube 2-1; opposite side edges of the stopper 3 are in contact with the first annular flange 4-3-1 and the sample collection tube 2-1, respectively. At this time, the sample eduction tube 2-1-2 at the bottom end of the sample collecting tube 2-1 is spaced from the sealing film of the cracking tube 2-3, and the distance is smaller than the width of the circular arc limiting portion 3-1 (i.e. the dimension of the circular arc limiting portion 3-1 along the direction of the center axis).

The circular arc limiting part 3-1 of the limiter 3 restrains the axial relative positions of the detection tube 4-3 and the sample collecting tube 2-1 in the initial state, so that the sample eduction tube 2-1-2 at the bottom end of the sample collecting tube 2-1 cannot puncture the sealing film at the bottom end of the cracking tube 2-3. After the limiter 3 is separated from the detection tube 4-3, the sample collecting tube 2-1 can be screwed continuously, so that the sample collecting tube 2-1 moves downwards to puncture the sealing film at the bottom end of the cracking tube 2-3.

In some embodiments, the circular arc limiter 3-1 corresponds to a central angle of 270 °.

In some embodiments, as shown in FIG. 1, two limit bumps 5 are provided on the bottom of the outer side surface of the connecting portion 2-1-1 and the top surface of the first annular flange 4-3-1; two clamping grooves 6 are arranged on the limiter 3. The two limit lugs 5 are matched with the two clamping grooves 6 in shape and position; when the limiter 3 is inserted between the connecting part 2-1-1 and the first annular flange 4-3-1, the two limiting lugs 5 are clamped into the two clamping grooves 6, so that the sample collecting pipe 2-1 and the detecting pipe 4-3 form a locking structure with the limiter 3; thereby realizing circumferential locking between the sample collecting pipe 2-1 and the detecting pipe 4-3 by utilizing the limiter 3; avoiding rotation of the sample collection tube 2-1 caused when the cap 1-1 is rotatably mounted or dismounted.

As shown in fig. 13, the working principle of the present utility model is as follows:

the process is as follows: and (5) sample collection. The sample absorber 1-6 of the collector 1 is placed into body fluid to be collected, whether the color change exists in the sampling progress indicating element 1-5 in the transparent collecting rod 1-3 is observed, and if the color change exists, the collection is proved to be finished.

A second flow: sample collection and cleavage reaction. The collector 1 for completing sample collection is placed in the sample collecting pipe 2-1, the inner thread of the sampling cover 1-1 of the collector 1 is screwed with the outer thread of the sample collecting cavity, so that the sample absorber 1-6 of the collector 1 and the bottom end of the inner cavity of the sample collecting pipe 2-1 are extruded, the liquid sample in the sample absorber 1-6 is fully released, flows into the cracking pipe 2-3 through the channel at the bottom of the sample collecting cavity, and fully reacts with the cracking agent in the cracking pipe 2-3.

And a process III: and (5) detecting a sample. When the sample in the cracking tube 2-3 is completely cracked, the limiter 3 buckled on the detection tube 4-3 is pulled out; rotating the sample collection tube until the sample collection tube is screwed with the detection tube 4-3; at this time, the sample eduction tube 2-1-2 at the bottom of the sample collection tube pierces the sealing film at the bottom of the cracking tube 2-3, and the cracked sample liquid flows into the detection tube 4-3 to be contacted with the reagent strip 4-2, so that detection is realized.

Claims (10)

1. An integrated device for collecting, storing and detecting body fluid samples comprises a sample collecting and splitting assembly (2) and a detection assembly (4); the method is characterized in that: also comprises a limiter (3); the sample collecting and cracking assembly (2) comprises a sample collecting pipe (2-1) and a cracking pipe (2-3); a cover body (1-1) is connected to the top opening of the sample collecting pipe (2-1); the outer side surface of the sample collecting pipe (2-1) is provided with a connecting part (2-1-1); the cracking tube (2-3) is sleeved outside the sample collecting tube (2-1); an opening is arranged at the bottom of the sample collecting pipe (2-1); a liquid outlet is arranged at the bottom end of the cracking tube (2-3); a sealing film is arranged on the liquid outlet; a membrane breaking structure aligned with the sealing membrane is arranged at the bottom of the sample collecting tube (2-1);

the detection component (4) comprises a reagent strip (4-2) and a detection tube (4-3); the reagent strip (4-2) is arranged on the inner side wall of the detection tube (4-3); the cracking tube (2-3) is arranged in the detection tube (4-3); the connecting part (2-1-1) of the sample collecting pipe (2-1) is connected with the opening of the detection pipe (4-3) and can adjust the relative position in the axial direction;

the limiter (3) is arranged between the detection tube (4-3) and the connecting part (2-1-1) of the sample collecting tube (2-1) and can be detached; in a state that the limiter (3) is not detached, the limiter (3) limits the axial relative positions of the sample collecting pipe (2-1) and the detection pipe (4-3) so that a membrane breaking structure at the bottom of the sample collecting pipe (2-1) is kept at a distance from a sealing membrane at the bottom end of the cracking pipe (2-3); under the state that the limiter (3) is detached, the axial position of the sample collecting pipe (2-1) can be adjusted relative to the detection pipe (4-3), so that a membrane breaking structure at the bottom of the sample collecting pipe (2-1) pierces a sealing membrane at the bottom end of the cracking pipe (2-3).

2. The integrated body fluid sample collection, storage and testing device of claim 1, wherein: and under the state that the limiter (3) is not detached, locking structures for locking the circumferential relative movement are formed between the limiter (3) and the detection tube (4-3) and between the limiter (3) and the sample collecting tube (2-1).

3. The integrated body fluid sample collection, storage and testing device of claim 1, wherein: the bottom end of the sample collecting pipe (2-1) is integrally formed with a sample eduction pipe (2-1-2); the inner cavity of the sample eduction tube (2-1-2) is communicated with the inner cavity of the sample collecting tube (2-1); the bottom end of the sample eduction tube (2-1-2) is provided with an inclined section used as a membrane rupture structure; the bottom surface of the inner cavity of the sample collecting pipe (2-1) and the bottom surface of the inner cavity of the cracking pipe (2-3) are both funnel-shaped and are provided with a hydrophobic coating.

4. The integrated body fluid sample collection, storage and testing device of claim 1, wherein: the top of the outer side surface of the detection tube (4-3) is provided with a first annular flange 4-3-1; the first annular flange 4-3-1 is aligned with the bottom edge of the connection (2-1-1) of the sample collection tube (2-1); in an initial state, the limiter (3) is arranged between the first annular flange 4-3-1 and the connecting part (2-1-1) of the sample collecting pipe (2-1); opposite side edges of the limiter (3) are respectively contacted with the first annular flange 4-3-1 and the sample collecting pipe (2-1); the membrane breaking structure at the bottom of the sample collecting pipe (2-1) and the sealing membrane of the cracking pipe (2-3) are arranged at intervals, and the interval is smaller than the width of the circular arc limiting part (3-1).

5. The integrated body fluid sample collection, storage and testing device of claim 4, wherein: limiting lugs (5) are arranged on the connecting part (2-1-1) and the first annular flange (4-3-1); a clamping groove (6) is arranged on the limiter (3); in the state that the limiter (3) is not detached, the limiting convex blocks (5) on the connecting part (2-1-1) and the first annular flange (4-3-1) are clamped into the clamping grooves (6) on the limiter (3).

6. The integrated body fluid sample collection, storage and testing device of claim 1, wherein: the limiter (3) comprises an arc limiting part (3-1), a holding part (3-2) arranged at the middle position of the outer side surface of the arc limiting part (3-1), and two mounting guide parts (3-3) respectively arranged at two ends of the arc limiting part (3-1); the arc limiting part (3-1) is made of elastic material and is in an excellent arc shape; the two installation guide parts (3-3) are gradually far away from each other from inside to outside; the top of the detection tube (4-3) is provided with a second external thread; the first annular flange 4-3-1 is lower than the second external thread; the arc limiting part (3-1) of the limiter (3) is sleeved outside the second external thread; the connecting part (2-1-1) of the sample collecting pipe (2-1) is annular, and the inner side of the connecting part is provided with a second internal thread; the second external thread is matched with the second internal thread in shape.

7. The integrated body fluid sample collection, storage and testing device of claim 1, wherein: the top of the outer side surface of the cracking tube (2-3) is integrally formed with a second annular flange (2-3-1); the second annular flange (2-3-1) is contacted with the edge of the top opening of the detection tube (4-3) to form axial positioning.

8. A body fluid sample collection, storage and testing integrated device according to any one of claims 1-7, wherein: also comprises a collector (1); the collector (1) comprises a collecting rod (1-3), a sampling progress indicating element (1-5) and a sample absorber (1-6); the inner end of the collecting rod (1-3) is fixed with the inner center of the cover body (1-1); the outer end of the collecting rod (1-3) is fixed with a sample absorber (1-6); the collecting rod (1-3) is in a transparent tubular shape with an open outer end; the sampling progress indicating element (1-5) is in a strip shape and is arranged in the inner cavity of the acquisition rod (1-3); the sampling progress indicating element (1-5) is in contact with the sample absorber (1-6); the sample absorber (1-6) is provided with a central hole; the outer end of the sampling progress indicating element (1-5) extends out of the inner cavity of the collecting rod (1-3) and extends into the central hole of the sample absorber (1-6); the value range of the length l of the part of the sampling progress indicating element (1-5) extending into the sample absorber (1-6) is 0.1 t-0.2 t; t is the length of the central hole of the sample absorber (1-6);

the outer end of the collecting rod (1-3) is provided with a suction head mounting part (1-3-1); the sample absorber (1-6) is coaxially fixed with the suction head mounting part (1-3-1); the suction head mounting part (1-3-1) is provided with a second sealing ring (1-4) for sealing the suction head mounting part (1-3-1) and the inner side wall of the sample collecting pipe (2-1); the sample absorber (1-6) is adhered and fixed with the outer end surface of the suction head mounting part (1-3-1); an annular groove (1-3-2) is arranged on the outer end surface of the suction head mounting part (1-3-1); the annular groove (1-3-2) divides the outer end face of the suction head mounting part (1-3-1) into a central boss and an annular flange which surrounds the outer side of the central boss at intervals; the opening of the inner cavity of the collecting rod (1-3) is positioned at the center of the center boss.

9. A body fluid sample collection, storage and testing integrated device according to any one of claims 1-8, wherein: the bottom of the outer side surface of the sample collecting pipe (2-1) is provided with a third sealing ring (2-2) for sealing between the outer side surface of the sample collecting pipe (2-1) and the inner side surface of the cracking pipe (2-3).

10. The integrated body fluid sample collection, storage and testing device of claim 9, wherein: the side wall of the cracking tube (2-3) is provided with an air guide through hole (2-3-2); the axial distance between the air guide through hole (2-3-2) and the sealing film is equal to the distance between the third sealing ring (2-2) and the outer end of the sample eduction tube (2-1-2).