CN220027058U - Quantitative pipetting device and sample detection equipment - Google Patents

Abstract

The utility model provides a quantitative pipetting device and sample detection equipment, the quantitative pipetting device includes: the sample storage unit is provided with a sample cavity for containing liquid to be detected; the quantitative liquid-transferring gun head is in sealing connection with the sample storage unit, the quantitative liquid-transferring gun head is provided with a conveying flow channel, a transition flow channel and a quantitative liquid-transferring flow channel with an opening which are communicated in sequence, the inner diameter of the transition flow channel is smaller than that of the conveying flow channel and larger than that of the transition flow channel, and the conveying flow channel is communicated with the sample cavity; the sealing cover is detachably connected to the quantitative pipetting gun head in a sealing mode and is used for sealing the opening. According to the quantitative liquid-transferring device, the sample storage unit, the quantitative liquid-transferring gun head and the sealing cover are in sealing connection, so that the tightness of the quantitative liquid-transferring device can be improved, the condition that liquid to be detected is polluted is avoided, and the accuracy of liquid-discharging control can be ensured while liquid discharging is smooth through the three-section channels of the conveying flow channel, the transition flow channel and the quantitative liquid-transferring flow channel of the quantitative liquid-transferring gun head, so that the quantitative performance of the quantitative liquid-transferring device is improved.

Description

Quantitative pipetting device and sample detection equipment

Technical Field

The utility model belongs to the technical field of detection instruments, and particularly relates to a quantitative pipetting device and sample detection equipment.

Background

Sample detection is widely applied to the fields of biology and chemistry, and various sample detection is involved in disease diagnosis. In the sample detection process, the liquid to be detected is usually required to be stored and transferred. Because the diagnosis needs to ensure the precision of sample detection, the accurate control of the transfer quantity of the liquid to be detected in the transfer process of the liquid to be detected is generally required.

At present, a simple injector is used as a pipetting device for storing and transferring liquid to be detected, and when the pipetting device is used, the liquid to be detected is added into the injector, and after shaking and mixing, the liquid to be detected is taken out for detection or amplification reaction is directly carried out; can gather the nose swab after also, put into the inside reagent of syringe with the nose swab head, rock the syringe after, with sample and reagent mixed wait to detect liquid ration drop into the detection indication box and show positive or negative through test paper or other modes, but simple and easy syringe structure is comparatively simple, can not guarantee the leakproofness before the sample shifts, more can not accurate control wait to detect liquid transfer volume, only can realize simple wait to detect liquid transfer function, makes sample detection precision lower, can not satisfy high accuracy disease diagnosis.

Disclosure of Invention

The utility model mainly aims to provide a quantitative pipetting device and sample detection equipment, and aims to solve the technical problems of poor tightness and quantification of pipetting devices in the prior art.

In order to achieve the above object, the present utility model provides a quantitative pipetting device comprising: the sample storage unit is provided with a sample cavity for containing liquid to be detected; the quantitative liquid-transferring gun head is in sealing connection with the sample storage unit, the quantitative liquid-transferring gun head is provided with a conveying flow channel, a transition flow channel and a quantitative liquid-transferring flow channel with an opening which are communicated in sequence, the inner diameter of the transition flow channel is smaller than that of the conveying flow channel and larger than that of the transition flow channel, and the conveying flow channel is communicated with the sample cavity; and the sealing cover is detachably connected to the quantitative pipetting gun head in a sealing way and is used for sealing the opening.

In an embodiment of the present utility model, the quantitative pipetting gun head includes: the conveying flow channel, the transition flow channel and the quantitative pipetting flow channel are all arranged on the main body barrel; the connecting cylinder is arranged outside the main body cylinder in a surrounding mode and forms a positioning groove with the main body cylinder, the positioning groove is used for the sample storage unit to extend into, and the inner cylinder wall of the connecting cylinder is in sealing connection with the sample storage unit.

In the embodiment of the utility model, the main body barrel comprises a main body section, a connecting section and a quantitative pipetting section which are sequentially connected and gradually reduced in section size, the conveying runner, the transition runner and the quantitative pipetting runner are respectively correspondingly arranged in the main body section, the connecting section and the quantitative pipetting section, and the connecting section is used for extending into the sealing cover and being in sealing connection with the sealing cover.

In the embodiment of the utility model, the outer wall of the connecting section is provided with an external thread for being in threaded connection with the sealing cover, and the wall thickness of the flow channel of the connecting section is larger than that of the flow channel of the main body section and that of the quantitative pipetting section.

In the embodiment of the utility model, the inner cylinder wall of the connecting cylinder is provided with an internal thread for being in threaded connection with the sample storage unit, and the thickness of the cylinder wall of the connecting cylinder is larger than that of the cylinder wall of the main body cylinder.

In an embodiment of the present utility model, the sample storage unit includes: the tube body assembly comprises an inner hose and an outer supporting tube sleeved outside the inner hose, and the sample cavity is formed in the inner hose; and a pressing assembly passing through the outer support tube and pressing the inner hose.

In an embodiment of the present utility model, the pressing assembly includes: the pressing frame comprises a pressing column extending into the outer supporting tube and a balancing plate used for balancing with the tube wall of the outer supporting tube; and the elastic resetting piece is supported between the trimming plate and the outer supporting tube and is used for driving the pressing frame to reset.

In the embodiment of the utility model, the inner diameter size of the quantitative pipetting channel gradually decreases from the transition channel to the opening direction.

In the embodiment of the utility model, a first anti-slip layer is arranged on the outer side of the quantitative pipetting gun head; and/or the outer side of the sealing cover is provided with a second anti-slip layer.

In an embodiment of the utility model, the sample detection device comprises a quantitative pipetting device as described above.

Through the technical scheme, the quantitative pipetting device provided by the embodiment of the utility model has the following beneficial effects:

after the sample storage unit of the quantitative pipetting device is used for preparing the liquid to be detected, the sample storage unit, the quantitative pipetting gun head and the sealing cover can be sequentially and hermetically connected, meanwhile, the opening of the quantitative pipetting gun head is sealed by the sealing cover, the leakage of the liquid to be detected can be avoided, the sealing cover can be detached relative to the quantitative pipetting gun head when the liquid to be detected is required to be quantitatively detected, the opening is opened, an external force is applied to the sample storage unit, the liquid to be detected in the sample cavity sequentially passes through the conveying runner, the transition runner and the quantitative pipetting runner, finally, the liquid to be detected flows out through the opening of the quantitative pipetting runner, the inner diameters of the conveying runner, the transition runner and the quantitative pipetting runner are sequentially reduced, the inner diameter of the conveying runner is the largest, the liquid to be detected in the sample cavity can conveniently and rapidly and smoothly enter the conveying runner, the inner diameter of the transition runner is between the inner diameter of the conveying runner and the inner diameter of the quantitative pipetting runner, the liquid to be detected can be buffered, the condition caused by abrupt change of the inner diameter is avoided, and the quantitative pipetting runner with the smallest inner diameter can accurately control the quantity of each drop passing through the opening. According to the quantitative liquid-transferring device, the sample storage unit, the quantitative liquid-transferring gun head and the sealing cover are in sealing connection, so that the tightness of the quantitative liquid-transferring device can be improved, the condition that liquid to be detected is polluted is avoided, and the accuracy of liquid-discharging control can be ensured while liquid discharging is smooth through the three-section channels of the conveying flow channel, the transition flow channel and the quantitative liquid-transferring flow channel of the quantitative liquid-transferring gun head, so that the quantitative performance of the quantitative liquid-transferring device is improved.

Additional features and advantages of the utility model will be set forth in the detailed description which follows.

Drawings

The accompanying drawings are included to provide an understanding of the utility model, and are incorporated in and constitute a part of this specification, illustrate the utility model and together with the description serve to explain, without limitation, the utility model. In the drawings:

FIG. 1 is a schematic view of a quantitative pipetting device according to an embodiment of the utility model;

FIG. 2 is a schematic cross-sectional view of a quantitative pipetting device in accordance with one embodiment of the utility model;

FIG. 3 is a schematic view of a quantitative pipetting gun head of a quantitative pipetting device in accordance with an embodiment of the utility model;

FIG. 4 is a schematic cross-sectional view of a quantitative pipetting gun head of a quantitative pipetting device in accordance with an embodiment of the utility model;

fig. 5 is a schematic view showing the structure of a sealing cover of a quantitative pipetting device in accordance with an embodiment of the utility model.

Description of the reference numerals

Reference number designation number designation

100. Transition flow channel of quantitative pipetting device 22

1. Quantitative liquid transfer channel of sample storage unit 23

11. Sample chamber 24 body cartridge

12. Main section of pipe body assembly 241

121. Inner hose 242 connecting section

122. Quantitative pipetting section of outer support tube 243

13. Press assembly 25 connecting cylinder

131. Positioning groove of pressing frame 26

1311. First anti-slip layer of pressing column 27

1312. 3 sealing covers of flat plate

132. Second anti-slip layer of elastic restoring piece 31

2. Quantitative pipetting gun head 200 sampling piece

21. Conveying runner

Detailed Description

Specific embodiments of the present utility model will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for purposes of illustration and explanation only and are not intended to limit the present utility model.

The quantitative pipetting device according to the utility model is described below with reference to the drawings.

As shown in fig. 1 to 5, in an embodiment of the present utility model, a quantitative pipetting device 100 includes a sample storage unit 1, a quantitative pipetting gun head 2 and a sealing cover 3; the sample storage unit 1 is provided with a sample cavity 11 for containing a liquid to be detected; the quantitative pipetting gun head 2 is in sealing connection with the sample storage unit 1, the quantitative pipetting gun head 2 is provided with a conveying flow passage 21, a transition flow passage 22 and a quantitative pipetting flow passage 23 with an opening which are communicated in sequence, the inner diameter of the transition flow passage 22 is smaller than that of the conveying flow passage 21 and larger than that of the transition flow passage 22, and the conveying flow passage 21 is communicated with the sample cavity 11; the sealing cover 3 is detachably connected to the quantitative pipetting gun head 2 in a sealing way, and the sealing cover 3 is used for sealing the opening.

It can be appreciated that the sample may be sampled by using a sampling member 200 such as a cotton swab, that is, the sampling member 200 is placed in the sample cavity 11, corresponding liquid is set to form the liquid to be detected, and an external force may be applied to the sample storage unit 1 by using a manual driving, hydraulic driving or mechanical driving manner, so that the liquid to be detected in the sample storage unit 1 enters the quantitative pipetting gun head 2. In one embodiment, to accurately control the liquid outlet amount of the liquid to be detected, the inner diameter of the opening is 0.4cm, so that the surface area of the liquid to be detected, which is in contact with the quantitative pipetting gun head 2, can be reduced during liquid dripping, the surface tension of the liquid can be reduced, and the liquid can be smoothly dripped. In other embodiments, the inner diameter of the opening may be set according to actual use requirements.

After the sample storage unit 1 of the quantitative pipetting device 100 in this embodiment is adopted for preparing the liquid to be detected, the sample storage unit 1, the quantitative pipetting gun head 2 and the sealing cover 3 can be sequentially and hermetically connected, meanwhile, the sealing cover 3 seals the opening of the quantitative pipetting gun head 2, the liquid to be detected can be prevented from leaking, the sealing cover 3 can be removed relative to the quantitative pipetting gun head 2 when the liquid to be detected needs to be quantitatively detected, the opening is opened, an external force is applied to the sample storage unit 1, the liquid to be detected in the sample cavity 11 sequentially passes through the conveying flow channel 21, the transition flow channel 22 and the quantitative pipetting flow channel 23, finally, the inner diameters of the conveying flow channel 21, the transition flow channel 22 and the quantitative pipetting flow channel 23 sequentially decrease through the opening of the quantitative pipetting flow channel 23, wherein the inner diameter of the conveying flow channel 21 is the largest, the liquid to be detected in the sample cavity 11 can be conveniently and rapidly and smoothly enter the conveying flow channel 21, the inner diameter of the transition flow channel 22 is between the inner diameter of the conveying flow channel 21 and the inner diameter of the quantitative pipetting flow channel 23, the liquid to be detected can be buffered, the condition that the inner diameter mutation causes the quantitative liquid to flow channel to flow can be prevented from flowing through the cut-off through the opening accurately. In this embodiment, through sealing connection among the three components of the sample storage unit 1, the quantitative pipetting gun head 2 and the sealing cover 3, the tightness of the quantitative pipetting device 100 can be improved, the condition that the liquid to be detected is polluted is avoided, and through the three-section type channels of the conveying flow channel 21, the transition flow channel 22 and the quantitative pipetting flow channel 23 of the quantitative pipetting gun head 2, the accuracy of liquid outlet control can be ensured while liquid outlet is smooth, and the quantitative performance of the quantitative pipetting device 100 is improved.

In one embodiment, the quantitative pipetting gun head 2 comprises a main body barrel 24 and a connecting barrel 25, and the conveying runner 21, the transition runner 22 and the quantitative pipetting runner 23 are all arranged on the main body barrel 24; the connecting cylinder 25 is arranged outside the main body cylinder 24 in a surrounding manner and surrounds the main body cylinder 24 to form a positioning groove 26 for the sample storage unit 1 to extend into, and the inner cylinder wall of the connecting cylinder 25 is in sealing connection with the sample storage unit 1. In this embodiment, the inner diameter of the connecting tube 25 is larger than that of the main body tube 24, the quantitative pipette tip 2 in this embodiment can be manufactured in an integrally formed manner, the connecting tube 25 and the main body tube 24 are connected by a slope, so that the quantitative pipette tip 2 can be conveniently demoulded in the manufacturing process, the sample storage unit 1 can extend into the positioning groove 26, the main body tube 24 can partially extend into the sample storage unit 1, and the connection convenience between the sample storage unit 1 and the quantitative pipette tip 2 is improved.

Specifically, the main body barrel 24 includes a main body section 241, a connecting section 242 and a quantitative pipetting section 243 which are sequentially connected and have gradually reduced cross-sectional sizes, and the conveying runner 21, the transition runner 22 and the quantitative pipetting runner 23 are respectively and correspondingly arranged in the main body section 241, the connecting section 242 and the quantitative pipetting section 243, and the connecting section 242 is used for extending into the sealing cover 3 and being in sealing connection with the sealing cover 3. In this embodiment, the cross-sectional dimensions of the main body section 241, the connecting section 242 and the quantitative pipetting section 243 are gradually reduced, and the main body section, the connecting section 242 and the quantitative pipetting channel 23 correspond to the conveying channel 21, the transition channel 22 and the quantitative pipetting channel 23 respectively, so that the manufacturing materials of the quantitative pipetting gun head 2 can be reduced, and the situation that the wall thickness of the quantitative pipetting gun head 2 is too thick is avoided.

As shown in fig. 2 and 3, in an embodiment, the outer wall of the connecting section 242 is provided with external threads for threaded connection with the sealing cap 3, and the flow passage wall thickness of the connecting section 242 is greater than the flow passage wall thickness of the main body section 241 and the flow passage wall thickness of the quantitative pipetting section 243. The connecting section 242 and the sealing cover 3 in this embodiment are in threaded sealing connection, and can be connected with the connecting section 242 by rotating the sealing cover 3, a sealing block for sealing the opening is arranged in the sealing cover 3, and then the sealing cover 3 is rotated, so that the sealing block can move along with the sealing cover 3 under the condition that the sealing cover 3 is separated from the quantitative pipette head 2, and the opening is opened.

As shown in fig. 2 and 4, in another embodiment, the inner cylinder wall of the connecting cylinder 25 is provided with an internal thread for screw-coupling with the cartridge 1, and the wall thickness of the connecting cylinder 25 is greater than that of the main body cylinder 24. The connecting cylinder 25 and the sample storage unit 1 in this embodiment are connected through threads, and the thickness of the cylinder wall of the connecting cylinder 25 is larger, so that the connection stability between the connecting cylinder 25 and the sample storage unit 1 can be ensured, the thickness of the flow channel wall of the connecting section 242 is larger, and the connection stability between the connecting section 242 and the sealing cover 3 can be ensured.

It should be noted that, the sample storage unit 1 includes a tube body assembly 12 and a pressing assembly 13, the tube body assembly 12 includes an inner hose 121 and an outer support tube 122 sleeved outside the inner hose 121, and the sample cavity 11 is opened in the inner hose 121; the pressing assembly 13 passes through the outer support tube 122 and serves to press the inner hose 121. The inner hose 121 in this embodiment may be made of plastic, and an assembly gap may be provided between the outer support tube 122 sleeved outside the inner hose 121 and the inner hose 121, so that the outer support tube 122 can be prevented from extruding the inner hose 121 inwards, and the liquid to be detected in the inner hose 121 is prevented from being extruded. The pressing component 13 in this embodiment may be disposed at a side portion of the sample storage unit 1, or may be disposed at an end portion of the sample storage unit 1 away from the sealing cover 3.

As shown in fig. 1 and 2, the pressing assembly 13 includes a pressing frame 131 and an elastic restoring member 132, the pressing frame 131 including a pressing post 1311 extending into the outer support tube 122, and a balancing plate 1312 for balancing with the tube wall of the outer support tube 122; the elastic restoring member 132 is supported between the balancing plate 1312 and the outer support tube 122, and is used for restoring the pressing frame 131. The elastic restoring member 132 in this embodiment may be a flat and thin elastic sheet, and when an external force is applied to the pressing frame 131, the elastic restoring member 132 is elastically compressed in the process of pressing the inner hose 121 by the pressing frame 131, and under the condition that the pipetting is completed and the external force is cancelled, the elastic restoring member 132 can drive the pressing frame 131 to restore under the action of the elastic force, so as to press again.

In one embodiment, the inner diameter of the quantitative transfer passage 23 is gradually reduced in size from the transition passage 22 toward the opening. In this embodiment, the cross section of the quantitative pipetting channel 23 is in a truncated cone shape, so that the inner diameter of the quantitative pipetting channel 23 is gradually reduced along the length direction, and the liquid is conveniently guided. As shown in fig. 3 to 5, specifically, the outside of the quantitative pipetting tip 2 is provided with a first anti-slip layer 27; and the second anti-slip layer 31 is provided on the outside of the sealing cap 3. The first anti-slip layer 27 and the second anti-slip layer 31 in this embodiment may be provided with anti-slip ribs or anti-slip patterns, which can facilitate the rotation of the quantitative pipette tip 2 and the sealing cover 3. For convenience of manufacture, the bottom of the sealing cover 3 in this embodiment may be arc-shaped.

In an embodiment of the present utility model, the sample detection apparatus includes the quantitative pipetting device 100 as described above, and the specific structure of the quantitative pipetting device 100 refers to the above-described embodiment. The sample detection device adopts all the technical solutions of all the embodiments, so that the sample detection device has at least all the beneficial effects brought by the technical solutions of the embodiments, and is not described in detail herein. The sample detection device may include a pipetting pump and a detector.

In the description of the present utility model, it should be understood that the terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present utility model, the meaning of "plurality" means at least two, for example, two, three, etc., unless specifically defined otherwise.

In the present utility model, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; may be mechanically connected, may be electrically connected or may be in communication with each other; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present utility model. In this specification, schematic representations of the above terms are not necessarily directed to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, the different embodiments or examples described in this specification and the features of the different embodiments or examples may be combined and combined by those skilled in the art without contradiction.

While embodiments of the present utility model have been shown and described above, it will be understood that the above embodiments are illustrative and not to be construed as limiting the utility model, and that variations, modifications, alternatives and variations may be made to the above embodiments by one of ordinary skill in the art within the scope of the utility model.

Claims (10)

1. A quantitative pipetting device, characterized in that the quantitative pipetting device (100) comprises:

a sample storage unit (1) provided with a sample chamber (11) for accommodating a liquid to be detected;

the quantitative pipetting gun head (2) is in sealing connection with the sample storage unit (1), the quantitative pipetting gun head (2) is provided with a conveying runner (21), a transition runner (22) and a quantitative pipetting runner (23) with an opening, which are sequentially communicated, the inner diameter of the transition runner (22) is smaller than the inner diameter of the conveying runner (21) and larger than the inner diameter of the transition runner (22), and the conveying runner (21) is communicated with the sample cavity (11);

the sealing cover (3) is detachably connected to the quantitative pipetting gun head (2) in a sealing mode, and the sealing cover (3) is used for sealing the opening.

2. The quantitative pipetting device according to claim 1, wherein the quantitative pipetting gun head (2) comprises:

the conveying flow channel (21), the transition flow channel (22) and the quantitative liquid transfer flow channel (23) are all arranged on the main body barrel (24);

the connecting cylinder (25) is arranged outside the main body cylinder (24) in a surrounding mode and surrounds a positioning groove (26) for the sample storage unit (1) to extend in, and the inner cylinder wall of the connecting cylinder (25) is in sealing connection with the sample storage unit (1).

3. The quantitative pipetting device according to claim 2, wherein the main body barrel (24) comprises a main body section (241), a connecting section (242) and a quantitative pipetting section (243) which are sequentially connected and gradually reduced in cross-sectional size, the conveying flow channel (21), the transition flow channel (22) and the quantitative pipetting flow channel (23) are respectively correspondingly arranged in the main body section (241), the connecting section (242) and the quantitative pipetting section (243), and the connecting section (242) is used for extending into the sealing cover (3) and being in sealing connection with the sealing cover (3).

4. A quantitative pipetting device according to claim 3, wherein the outer wall of the connecting section (242) is provided with an external thread for a threaded connection with the sealing cap (3), and the flow channel wall thickness of the connecting section (242) is greater than the flow channel wall thickness of the main body section (241) and the flow channel wall thickness of the quantitative pipetting section (243).

5. Quantitative pipetting device according to claim 2, wherein the inner cylinder wall of the connecting cylinder (25) is provided with an internal thread for a threaded connection with the sample storage unit (1), the cylinder wall thickness of the connecting cylinder (25) being greater than the cylinder wall thickness of the main body cylinder (24).

6. Quantitative pipetting device according to claim 1, wherein the inner diameter dimension of the quantitative pipetting channel (23) decreases gradually from the transition channel (22) towards the opening.

7. The quantitative pipetting device according to claim 1, wherein a first anti-slip layer (27) is provided on the outside of the quantitative pipetting tip (2);

and/or the number of the groups of groups,

the outer side of the sealing cover (3) is provided with a second anti-slip layer (31).

8. Quantitative pipetting device according to any one of claims 1 to 7, wherein the sample storage unit (1) comprises:

the tube body assembly (12) comprises an inner hose (121) and an outer supporting tube (122) sleeved outside the inner hose (121), and the sample cavity (11) is formed in the inner hose (121);

a pressing assembly (13) passing through the outer support tube (122) and for pressing the inner hose (121).

9. The quantitative pipetting device according to claim 8, wherein the pressing assembly (13) comprises:

a press frame (131) comprising a press post (1311) extending into the outer support tube (122), and a trim plate (1312) for trimming with the tube wall of the outer support tube (122);

and the elastic reset piece (132) is supported between the trimming plate (1312) and the outer supporting tube (122) and is used for driving the pressing frame (131) to reset.

10. A sample testing device, characterized in that it comprises a quantitative pipetting device (100) according to any one of claims 1 to 9.