CN219984727U - Quantitative pipetting device and sample detection equipment - Google Patents

Abstract

The present utility model provides a quantitative pipetting device and a sample detection apparatus, the quantitative pipetting device comprising: a pressing assembly; an inner hose provided with a sample cavity with an outlet for accommodating a liquid to be detected; the outer support tube is sleeved outside the inner hose and forms a support gap with the inner hose, an anti-falling structure is arranged between the outer support tube and the inner hose and used for resisting the side tube wall of the inner hose along the extending direction of the inner hose, and the pressing component is used for extending into the outer support tube and extruding the inner hose. According to the utility model, the outer support tube and the inner hose are mutually matched to form the double-layer sleeve, and the anti-drop structure is arranged between the outer support tube and the inner hose to form the support gap, so that inaccurate liquid transfer quantity control and inconvenient liquid transfer caused by over-hard and over-soft inner hose can be avoided on the basis of ensuring the use stability.

Description

Quantitative pipetting device and sample detection equipment

Technical Field

The utility model belongs to the technical field of detection instruments, and particularly relates to a quantitative pipetting device and sample detection equipment.

Background

Sample detection is widely applied to the fields of biology and chemistry, and various sample detection is involved in disease diagnosis. In the sample detection process, the sample is required to be added into a pipetting device, shaken and mixed uniformly, and then taken out for detection, or the sample is subjected to a direct amplification reaction, so that the liquid to be detected is usually required to be stored and transferred. Since the diagnosis needs to ensure the accuracy of sample detection, it is generally required to maintain a sealed state before sample transfer, so as to avoid sample contamination, and accurately control the sample transfer amount during sample transfer.

However, in the current market, the pipetting device usually performs sample transfer by directly squeezing the tube, for example, the authorized bulletin number is: CN212925026U is a sampling tube capable of quantitatively transferring samples. However, in the structure form of the directly extruded tube body, under the condition that the tube body is too soft, sample transfer control is inaccurate, liquid is excessively transferred with little force, the condition that the detection precision of liquid to be detected is low is caused, and under the condition that the tube body is too hard, extrusion is not smooth, so that the operation is inconvenient and the detection efficiency is reduced.

Disclosure of Invention

The utility model mainly aims to provide a quantitative pipetting device and sample detection equipment, and aims to solve the technical problems that pipetting device pipetting amount control is inaccurate and pipetting is inconvenient in the prior art.

In order to achieve the above object, the present utility model provides a quantitative pipetting device comprising: a pressing assembly; an inner hose provided with a sample cavity with an outlet for accommodating a liquid to be detected; the outer support tube is sleeved outside the inner hose and forms a support gap with the inner hose, an anti-falling structure is arranged between the outer support tube and the inner hose and used for resisting the side tube wall of the inner hose along the extending direction of the inner hose, and the pressing component is used for extending into the outer support tube and extruding the inner hose.

In an embodiment of the present utility model, the anti-falling structure includes a hose protruding strip and a supporting protruding strip, the hose protruding strip is disposed on the inner hose, and the supporting protruding strip is disposed on the outer support tube.

In the embodiment of the utility model, the inner wall of the outer supporting tube is provided with a plurality of positioning ribs at intervals, and the positioning ribs enclose a positioning cavity into which the inner hose extends.

In the embodiment of the utility model, the pipe wall thickness of the inner hose gradually decreases from the hose convex strip to the direction of the positioning rib, and the pressing component is arranged close to the end part of the inner hose and is used for pressing the side pipe wall of the inner hose.

In an embodiment of the present utility model, the hose protruding strip is disposed around the outer pipe wall of the inner hose, and the central axes of the hose protruding strip and the inner hose are overlapped, the number of the supporting protruding strips is plural, and the supporting protruding strips are disposed at intervals along the inner pipe wall of the outer supporting pipe.

In the embodiment of the utility model, a positioning baffle plate abutting against the outer supporting tube is arranged on the outer periphery of the inner hose, and the positioning baffle plate is positioned between the outlet and the hose convex strip.

In the embodiment of the utility model, a plurality of reinforcing ribs are connected between the hose raised strips and the positioning baffle plate, and the reinforcing ribs are arranged at intervals around the outer pipe wall of the inner hose.

In an embodiment of the present utility model, the pressing assembly includes: the pressing frame comprises a pressing column extending into the outer supporting tube and a balancing plate used for balancing with the tube wall of the outer supporting tube; and the elastic resetting piece is supported between the trimming plate and the outer supporting tube and is used for driving the pressing frame to reset.

In an embodiment of the present utility model, the quantitative pipetting device further includes: the quantitative liquid-transferring gun head is in sealing connection with the inner hose, the quantitative liquid-transferring gun head is provided with a conveying runner, a transition runner and a quantitative liquid-transferring runner with an opening, the conveying runner is communicated with the sample cavity in sequence, the inner diameter of the transition runner is smaller than that of the conveying runner and larger than that of the transition runner, and the conveying runner is communicated with the sample cavity; and the sealing cover is detachably connected to the quantitative pipetting gun head in a sealing way and is used for sealing the opening.

In an embodiment of the utility model, the sample detection device comprises a quantitative pipetting device as described above.

Through the technical scheme, the quantitative pipetting device provided by the embodiment of the utility model has the following beneficial effects:

the outer support pipe is sleeved outside the inner hose, so that a supporting gap is formed between the inner hose and the outer support pipe, the condition that the liquid transferring control is inaccurate due to the fact that the outer support pipe is in large-area contact with the inner hose can be avoided, the anti-drop structure is arranged between the inner hose and the outer support pipe, the double-layer sleeve can be prevented from being separated, the use stability of the quantitative liquid transferring device is guaranteed, the pressing assembly penetrates through the outer support pipe, after the preparation of liquid to be detected is completed, external force can be applied to the pressing assembly, the pressing assembly presses the inner hose, and the inner hose is extruded through the fixed volume, so that the volume of liquid drops extruded out each time reaches the quantitative requirement, the quantitative requirement of liquid to be detected is met, and the quantitative liquid transferring device is more beneficial to detection. According to the utility model, the outer support tube and the inner hose are mutually matched to form the double-layer sleeve, and the anti-drop structure is arranged between the outer support tube and the inner hose to form the support gap, so that inaccurate liquid transfer quantity control and inconvenient liquid transfer caused by over-hard and over-soft inner hose can be avoided on the basis of ensuring the use stability.

Additional features and advantages of the utility model will be set forth in the detailed description which follows.

Drawings

The accompanying drawings are included to provide an understanding of the utility model, and are incorporated in and constitute a part of this specification, illustrate the utility model and together with the description serve to explain, without limitation, the utility model. In the drawings:

FIG. 1 is a schematic cross-sectional view of a quantitative pipetting device in accordance with one embodiment of the utility model;

FIG. 2 is a schematic view of the inner hose structure of the quantitative pipetting device in accordance with one embodiment of the utility model;

FIG. 3 is a schematic view showing the structure of an outer support tube of the quantitative pipetting device in accordance with one embodiment of the utility model;

fig. 4 is a schematic view showing a part of the structure of a quantitative pipetting device in accordance with an embodiment of the utility model.

Description of the reference numerals

Reference number designation number designation

100. Quantitative pipetting device 311 pressing column

1. Inner hose 312 trimming plate

11. Elastic restoring piece for sample cavity 32

12. Quantitative liquid-transferring gun head with flexible pipe convex strip 4

13. Positioning baffle 41 conveying flow channel

14. Reinforcing rib 42 transition flow passage

2. Outer support tube 43 quantitative liquid transfer channel

21. Support convex strip 5 sealing cover

22. The positioning ribs 6 support the clearance

3. Press assembly 200 sampling member

31. Press rack

Detailed Description

Specific embodiments of the present utility model will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for purposes of illustration and explanation only and are not intended to limit the present utility model.

The quantitative pipetting device according to the utility model is described below with reference to the drawings.

As shown in fig. 1 to 4, in an embodiment of the present utility model, a quantitative pipetting device 100 includes an inner hose 1, an outer support tube 2 and a pressing assembly 3; the inner hose 1 is provided with a sample chamber 11 with an outlet for containing the liquid to be detected; the outer support tube 2 is sleeved outside the inner hose 1 and forms a support gap 6 with the inner hose 1, an anti-falling structure is arranged between the outer support tube 2 and the inner hose 1 and used for resisting the side tube wall of the inner hose 1 along the extending direction of the inner hose 1, and the pressing component 3 is used for extending into the outer support tube 2 and extruding the inner hose 1.

It can be understood that in this embodiment, the hardness of the outer support tube 2 is greater than that of the inner hose 1, and the outer support tube 2 can protect the inner hose 1, so as to avoid leakage of the liquid to be detected or excessive transfer of the liquid to be detected caused by false touch of the inner hose 1. The sample can be sampled by adopting the sampling piece 200 such as a cotton swab, after the cotton swab sampling is completed, the cotton swab is put into the sample cavity 11 of the inner hose 1, and the whole quantitative pipetting device 100 is shaken, so that the cotton swab and the liquid in the sample cavity 11 are fully mixed. An external force can be applied to the pressing assembly 3 by manual driving, hydraulic driving or mechanical driving, so that the liquid to be detected in the inner hose 1 flows out from the outlet. The pressing assembly 3 may be provided at a side or end of the inner hose 1.

The outer support tube 2 in the embodiment can be firstly sleeved outside the inner hose 1, a supporting gap 6 is formed between the inner hose 1 and the outer support tube 2, the condition that the liquid transferring control is inaccurate due to the fact that the outer support tube 2 contacts the inner hose 1 in a large area can be avoided, an anti-drop structure is arranged between the inner hose 1 and the outer support tube 2, the double-layer sleeve can be avoided, the use stability of the quantitative liquid transferring device 100 is guaranteed, the pressing component 3 penetrates through the outer support tube 2, after the preparation of liquid to be detected is completed, external force can be applied to the pressing component 3, the pressing component 3 presses the inner hose 1, the contact area between the pressing component 3 and the inner hose 1 is fixed, the inner hose 1 is extruded through the fixed volume, the liquid drop volume extruded each time reaches the quantitative requirement, the quantitative requirement of the liquid to be detected is met, and the detection accuracy is facilitated. In this embodiment, through the mutual cooperation of outer stay tube 2 and interior hose 1, and set up anticreep structure and form supporting gap 6 between outer stay tube 2 and interior hose 1, can avoid the liquid transfer volume control inaccuracy and the liquid transfer inconvenience that the soft too hard of interior hose 1 leads to on the basis of guaranteeing stability in use.

The anti-drop structure includes a hose ridge 12 and a support ridge 21, the hose ridge 12 is provided on the outer tube wall of the inner hose 1, and the support ridge 21 is provided on the inner wall of the outer support tube 2. In this embodiment, the contact area between the hose raised line 12 and the supporting raised line 21 is smaller, the outer surfaces of the hose raised line 12 and the supporting raised line 21 are arc surfaces, after the inner hose 1 is assembled in place, the supporting raised line 21 is located between the hose raised line 12 and the outlet, the hose raised line 12 can be blocked in the direction close to the outlet, the side wall of the inner hose 1 can be blocked in the vertical direction, and the situation that the outer support tube 2 excessively extrudes the inner hose 1 to cause a large amount of liquid to flow out of the inner hose 1 in a short time can be avoided.

As shown in fig. 1 to 3, the inner hose 1 and the outer support tube 2 extend in the vertical direction, the inner diameter of the sample chamber 11 gradually decreases from the bottom to the outlet, the hose raised strips 12 and the support raised strips 21 in this embodiment can interfere in the vertical direction, the inner hose 1 is prevented from being separated from the outer support tube 2 in the vertical direction, and meanwhile, in this embodiment, the walls of the inner hose 1 and the outer support tube 2 except the hose raised strips 12 and the support raised strips 21, which are involved up and down, are not contacted, the condition that the inner hose 1 is not accurately controlled due to the extrusion of the outer support tube 2 by the inner hose 1 can be avoided, and the inner hose 1 is extruded only by the pressing component 3.

In an embodiment, a plurality of positioning ribs 22 are arranged on the inner wall of the outer support tube 2 at intervals, and the positioning ribs 22 enclose a positioning cavity into which the inner hose 1 extends. The shape of the positioning rib 22 in this embodiment can be profiled according to the inner hose 1, the positioning rib 22 extends from the lower end of the outer support tube 2 to the direction close to the hose raised line 12, the length of the positioning rib 22 is half of the length of the outer support tube 2, the size of the positioning cavity is larger than the cross-section size of the inner hose 1 under the condition that the inner hose 1 and the outer support tube 2 are assembled in place, the positioning rib 22 and the inner hose 1 are arranged at intervals, and the positioning cavity can primarily position and guide the inner hose 1 during the assembly of the inner hose 1 and the outer support tube 2, so that the influence of positioning offset on quantification during initial loading is reduced.

Specifically, as shown in fig. 1, the wall thickness of the inner hose 1 gradually decreases from the hose ridge 12 toward the positioning rib 22, and the pressing assembly 3 is disposed near the end of the inner hose 1 and is used to press the side wall of the inner hose 1. In this embodiment, the wall thickness of the side tube of the inner tube 1 is uneven along the length direction, the wall thickness of the upper portion of the inner tube 1 is thicker, the wall thickness of the extrusion position is thinner, the extrusion is facilitated, and the operation convenience of the quantitative pipetting device 100 is improved.

As shown in fig. 2 and 3, the hose ridge 12 is disposed around the outer pipe wall of the inner hose 1, the central axes of the hose ridge 12 and the inner hose 1 overlap, the number of the support ridge 21 is plural, and the plural support ridges 21 are disposed at intervals along the inner pipe wall of the outer support pipe 2. The hose raised strips 12 in the embodiment completely encircle the inner hose 1, so that the structural strength of the inner hose 1 is enhanced, and the anti-falling stability between the inner hose 1 and the outer support tube 2 can be improved. The plurality of support ribs 21 are each engageable with the hose rib 12 to prevent disengagement.

In one embodiment, the outer circumference of the inner hose 1 is provided with a positioning baffle 13 abutting the outer support tube 2, the positioning baffle 13 being located between the outlet and the hose rib 12. The cross-sectional dimension of the positioning baffle 13 in this embodiment is larger than that of the outer support plate, so that a sufficient limiting area between the inner hose 1 and the outer support tube 2 can be ensured. The positioning ribs 22 are positioned between the supporting convex strips 21 and the lower end part of the outer supporting tube 2.

In the embodiment of the present utility model, a plurality of reinforcing ribs 14 are connected between the hose convex strips 12 and the positioning baffle 13, and the plurality of reinforcing ribs 14 are arranged at intervals around the outer pipe wall of the inner hose 1. The reinforcing ribs 14 in the embodiment are long, so that the strength of the upper part of the inner hose 1 can be further improved, and the situation that the inner hose 1 is transferred to the liquid to be detected due to false touch is avoided.

As shown in fig. 1, the pressing assembly 3 includes a pressing frame 31 and an elastic restoring member 32; the pressing frame 31 includes a pressing post 311 extending into the outer support tube 2 and a trimming plate 312 for trimming with the tube wall of the outer support tube 2; the elastic restoring member 32 is supported between the balancing plate 312 and the outer support tube 2 and serves to restore the pressing frame 31. In the embodiment, the elastic restoring member 32 may be a flat and thin elastic sheet, and in the process of applying an external force to the pressing frame 31 to make the pressing frame 31 squeeze the inner hose 1, the elastic restoring member 32 is elastically compressed, and under the condition that the pipetting is completed and the external force is cancelled, the elastic restoring member 32 can drive the pressing frame 31 to restore under the action of the elastic force so as to facilitate the re-pressing.

In one embodiment, the quantitative pipetting device 100 further comprises a quantitative pipetting gun head 4 and a sealing cover 5: the quantitative liquid-transferring gun head 4 is in sealing connection with the inner hose 1, the quantitative liquid-transferring gun head 4 is provided with a conveying runner 41, a transition runner 42 and a quantitative liquid-transferring runner 43 with an opening, which are communicated in sequence, the inner diameter of the transition runner 42 is smaller than that of the conveying runner 41 and larger than that of the transition runner 42, and the conveying runner 41 is communicated with the sample cavity 11; and the sealing cover 5 is detachably and hermetically connected to the quantitative pipetting gun head 4, and the sealing cover 5 is used for sealing the opening.

After the preparation of the liquid to be detected is carried out in the sample cavity 11, the inner hose 1, the quantitative liquid-transferring gun head 4 and the sealing cover 5 can be sequentially connected in a sealing manner, meanwhile, the sealing cover 5 seals the opening of the quantitative liquid-transferring gun head 4, the liquid to be detected can be prevented from leaking, sealing and preserving can be carried out on the liquid to be detected, when the liquid to be detected needs to be quantitatively detected, the sealing cover 5 can be detached relative to the quantitative liquid-transferring gun head 4, the opening is opened, an external force is applied to the inner hose 1, the liquid to be detected in the sample cavity 11 sequentially passes through the conveying flow channel 41, the transition flow channel 42 and the quantitative liquid-transferring flow channel 43, finally, the inner diameters of the conveying flow channel 41, the transition flow channel 42 and the quantitative liquid-transferring flow channel 43 sequentially decrease, wherein the inner diameter of the conveying flow channel 41 is the largest, the liquid to be detected in the sample cavity 11 can be conveniently and rapidly and smoothly enter the conveying flow channel 41, the inner diameter of the transition flow channel 42 can be buffered between the inner diameter of the conveying flow channel 41 and the inner diameter of the quantitative liquid-transferring flow channel 43, the condition caused by the inner diameter mutation is avoided, and the condition that the inner diameter mutation is caused is avoided, and finally, the inner diameter of the quantitative liquid to be detected can flow through the accurate control of each cut-off opening. In this embodiment, the sealing performance of the quantitative pipetting device 100 can be improved by the threaded sealing connection among the three components of the inner hose 1, the quantitative pipetting gun head 42 and the sealing cover 5, the situation that the liquid to be detected is polluted is avoided, and the accuracy of liquid outlet control can be ensured while liquid outlet is smooth by the three-section channels of the conveying channel 41, the transition channel 42 and the quantitative pipetting channel 43 of the quantitative pipetting gun head 4, so that the quantitative performance of the quantitative pipetting device 100 is improved.

The present utility model also proposes a sample detection apparatus comprising a quantitative pipetting device 100 as described above, the specific structure of the quantitative pipetting device 100 being referred to the above embodiments. The sample detection device adopts all the technical solutions of all the embodiments, so that the sample detection device has at least all the beneficial effects brought by the technical solutions of the embodiments, and is not described in detail herein. The sample detection device may include a pipetting pump and a detector.

In the description of the present utility model, it should be understood that the terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present utility model, the meaning of "plurality" means at least two, for example, two, three, etc., unless specifically defined otherwise.

In the present utility model, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; may be mechanically connected, may be electrically connected or may be in communication with each other; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present utility model. In this specification, schematic representations of the above terms are not necessarily directed to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, the different embodiments or examples described in this specification and the features of the different embodiments or examples may be combined and combined by those skilled in the art without contradiction.

While embodiments of the present utility model have been shown and described above, it will be understood that the above embodiments are illustrative and not to be construed as limiting the utility model, and that variations, modifications, alternatives and variations may be made to the above embodiments by one of ordinary skill in the art within the scope of the utility model.

Claims (10)

1. A quantitative pipetting device, characterized in that it comprises:

an inner hose (1) provided with a sample chamber (11) with an outlet for containing a liquid to be detected;

the outer support tube (2) is sleeved outside the inner hose (1) and forms a support gap (6) with the inner hose (1), an anti-falling structure is arranged between the outer support tube (2) and the inner hose (1), and the anti-falling structure is used for resisting the side tube wall of the inner hose (1) along the extending direction of the inner hose (1);

and the pressing component (3) is used for extending into the outer supporting tube (2) and extruding the inner hose (1).

2. The quantitative pipetting device according to claim 1, wherein the anti-drop structure comprises a hose bead (12) and a support bead (21), the hose bead (12) being arranged in the inner hose (1), the support bead (21) being arranged in the outer support tube (2).

3. Quantitative pipetting device according to claim 2, wherein a plurality of positioning ribs (22) are arranged on the inner wall of the outer support tube (2) at intervals, and a plurality of positioning ribs (22) enclose a positioning cavity into which the inner hose (1) extends.

4. A quantitative pipetting device according to claim 3, wherein the tube wall thickness of the inner tube (1) decreases gradually from the tube ridge (12) to the positioning rib (22), and the pressing assembly (3) is arranged near the end of the inner tube (1) and is used for pressing the side tube wall of the inner tube (1).

5. The quantitative pipetting device according to claim 2, wherein the hose ribs (12) are looped around the outer tube wall of the inner hose (1), and the central axes of the hose ribs (12) and the inner hose (1) coincide, the number of the support ribs (21) is plural, and the plurality of support ribs (21) are arranged at intervals along the inner tube wall of the outer support tube (2).

6. Quantitative pipetting device according to claim 2, wherein the outer circumference of the inner hose (1) is provided with a positioning baffle (13) abutting the outer support tube (2), the positioning baffle (13) being located between the outlet and the hose bead (12).

7. The quantitative pipetting device according to claim 6, wherein a plurality of reinforcing ribs (14) are connected between the hose ribs (12) and the positioning baffle (13), and the plurality of reinforcing ribs (14) are arranged at intervals around the outer tube wall of the inner hose (1).

8. The quantitative pipetting device according to any one of claims 1 to 7, wherein the pressing assembly (3) comprises:

a pressing frame (31) comprising a pressing column (311) extending into the outer support tube (2), and a balancing plate (312) for balancing with the tube wall of the outer support tube (2);

and the elastic reset piece (32) is supported between the trimming plate (312) and the outer supporting tube (2) and is used for driving the pressing frame (31) to reset.

9. The quantitative pipetting device according to any one of claims 1 to 7, wherein the quantitative pipetting device (100) further comprises:

the quantitative liquid-transferring gun head (4) is in sealing connection with the inner hose (1), the quantitative liquid-transferring gun head (4) is provided with a conveying flow channel (41), a transition flow channel (42) and a quantitative liquid-transferring flow channel (43) with an opening which are communicated in sequence, the inner diameter of the transition flow channel (42) is smaller than the inner diameter of the conveying flow channel (41) and larger than the inner diameter of the transition flow channel (42), and the conveying flow channel (41) is communicated with the sample cavity (11);

and the sealing cover (5) is detachably connected to the quantitative pipetting gun head (4) in a sealing way, and the sealing cover (5) is used for sealing the opening.

10. A sample testing device, characterized in that it comprises a quantitative pipetting device (100) according to any one of claims 1 to 9.