CN210700181U - Trace liquid collecting and filling device - Google Patents
Trace liquid collecting and filling device Download PDFInfo
- Publication number
- CN210700181U CN210700181U CN201921572434.3U CN201921572434U CN210700181U CN 210700181 U CN210700181 U CN 210700181U CN 201921572434 U CN201921572434 U CN 201921572434U CN 210700181 U CN210700181 U CN 210700181U
- Authority
- CN
- China
- Prior art keywords
- sleeve
- capillary tube
- capillary
- liquid
- filling device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Abstract
The utility model discloses a trace liquid collecting and filling device, which comprises an air bag and a sleeve communicated with the air bag, wherein a capillary tube is inserted in the lower part of the sleeve, and the bottom of the capillary tube extends outwards to form the sleeve; and an exhaust assembly communicated with the sleeve is arranged on the side wall of the sleeve corresponding to the capillary, and the height of the top air inlet of the exhaust assembly is higher than that of the top orifice of the capillary. The utility model has simple and ingenious structure and low processing cost, the capillary tube is inserted in the lower part of the sleeve in a sealing way, the inner diameters of the capillary tube and the sleeve are completely inconsistent, and the inner surface of the capillary tube is provided with the hydrophilic surface modified coating, thereby destroying the liquid climbing action force at the junction of the top orifice of the capillary tube and the sleeve, ensuring that the liquid does not rise after being quickly filled in the capillary tube, and realizing the quick and high-precision quantitative collection of the liquid; according to the drop volume principle, the accurate filling of the liquid is realized; when in mixing, the bottom air outlet and the capillary tube are inserted below the liquid level, and the air bag is repeatedly extruded to realize quick mixing of different liquids, so that the operation is simple.
Description
Technical Field
The utility model relates to a liquid collection system especially relates to a trace liquid gathers filling device.
Background
With the rapid development of clinical diagnosis technology, the joint detection of multiple project biochemical indexes by using a trace liquid sample is widely applied in the field of clinical diagnosis. The traditional method for collecting, mixing and filling the trace samples is to quantitatively collect the samples by using a pipette, mix the samples by adjusting the range of the pipette or replacing the pipette with a large range, and sample again by adjusting the range of the pipette or replacing the pipette after mixing. Therefore, the whole collection, mixing and filling process needs to be matched with a plurality of pipette guns with different measuring ranges, and the detection cost is high; the whole operation process needs to repeatedly adjust the measuring range of the liquid-transfering gun (or repeatedly replace the liquid-transfering gun) and the gun head (namely the tip head), the operation is complicated, and misoperation caused by memory disorder is easy to occur particularly.
Therefore, the conventional detection usually adopts a micropipette and a rubber suction head with volume marks, so that the detection cost is reduced, but the following problems exist in the actual detection: firstly, once the transportation or the storage is improper, the mark lines are easy to be blurred, and the waste is serious; secondly, the sampling speed is slow, and the time consumption is long; thirdly, the rubber suction head can not accurately control the liquid collection amount at all, over-suction is easy to occur, the sampling error is large, and the detection results are completely opposite when the over-suction is serious, so that misdiagnosis is caused. Therefore, how to design a micro liquid collecting and filling device with fast sampling speed and high quantitative accuracy is a goal that is constantly pursued by those skilled in the art.
Disclosure of Invention
An object of the utility model is to provide a sampling rate is fast and sampling, the accurate high trace liquid collection filling device of the accurate nature of application of sample, can realize the quick high accuracy ration of sample and annotate the appearance with the ration, can also realize the drawing of sample and beat the mixing, is particularly useful for kit detection area.
In order to achieve the above purpose, the utility model adopts the following technical proposal:
the utility model discloses a trace liquid collecting and filling device, which comprises an air bag and a sleeve communicated with the air bag, wherein a capillary tube is inserted in the lower part of the sleeve, and the bottom of the capillary tube extends outwards to form the sleeve; and an exhaust assembly communicated with the sleeve is arranged on the side wall of the sleeve corresponding to the capillary, and the height of the top air inlet of the exhaust assembly is higher than that of the top orifice of the capillary.
The exhaust assembly comprises a reinforcing sheet integrally formed with the sleeve, an exhaust channel with a broken line structure is arranged on the reinforcing sheet, and the height difference between the top air inlet of the exhaust channel and the top orifice of the capillary tubeΔHIs 1 mm-2 mm.
The exhaust passage comprises an inclined section communicated with the sleeve and a vertical section vertically extending downwards from the right end of the inclined section, an included angle α between the inclined section and the sleeve is 60-90 degrees, the lower part of the vertical section is inwards folded downwards to form a bottom air outlet in a circular truncated cone-shaped structure, and the bottom air outlet extends downwards to the bottom of the sleeve.
A length of capillary tube extending out of the sleeveL≥5 mm。
The inner surface of the capillary tube is coated with a hydrophilic surface modifying coating.
The air bag is connected with the sleeve into a whole through a connecting pipe, and the volume of the sleeve is larger than that of the air bag.
The connecting pipe is of a circular truncated cone-shaped structure with a large upper part and a small lower part.
The utility model has the advantages of simple structure, ingenious, the processing cost is low, utilizes capillary phenomenon to realize the quick quantitative sampling of trace liquid, can also realize gathering the drawing of liquid or other liquid and beat the mixing, easy operation, convenient. Specifically, a capillary tube is hermetically inserted in the lower part of the sleeve, the inner diameters of the capillary tube and the sleeve are completely different, and a hydrophilic surface modified coating is arranged on the inner surface of the capillary tube, so that the liquid climbing acting force at the junction of a top nozzle of the capillary tube and the sleeve is destroyed, the capillary tube is not lifted after being quickly filled with liquid, the quick and high-precision quantitative collection of the liquid is realized, and meanwhile, the accurate filling of the liquid is realized according to the drop volume principle; when in mixing, the bottom air outlet and the capillary tube are inserted below the liquid level, and the air bag is repeatedly extruded to realize quick mixing of different liquids, so that the operation is simple; the connecting pipe is of a round table structure, and the residual volume of liquid in the mixing process is reduced.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is an enlarged schematic view of a portion a in fig. 1.
Detailed Description
As shown in figures 1 and 2, the micro-liquid collecting and filling device comprises an air bag 1 and a sleeve 2 communicated with the air bag 1, the air bag 1 is connected with the sleeve 2 into a whole through a connecting pipe 8 which is a round platform-shaped structure, the lower part of the sleeve 2 is internally inserted with a capillary 3 of which the inner surface is coated with a hydrophilic modified coating, the bottom of the capillary 3 outwards extends out of the sleeve 2, and the length of the capillary 3 extending out of the sleeve 2 is 3L5mm (or 5.1mm, 5.2mm, 5.3mm, etc.), an exhaust assembly communicated with the sleeve 2 is arranged on the side wall of the sleeve 2 at the position corresponding to the capillary tube 3, the exhaust assembly comprises a reinforcing sheet 4 integrally formed with the sleeve 2, an exhaust channel in a broken line structure is formed on the reinforcing sheet 4, the exhaust channel comprises an inclined section 5 communicated with the sleeve 2 and a vertical section 6 extending downwards from the right end of the inclined section 5, an included angle α between the inclined section 5 and the sleeve 2 is 90 degrees (or any angle within the range of 60 to 90 degrees), the height of a top air inlet of the inclined section 5 is higher than that of a top tube opening of the capillary tube 3, and the height difference between the top air inlet and the top tube opening of the capillary tube 3ΔH1 mm-2 mm, so that the liquid does not rise any more when rising to the top pipe orifice of the capillary 3; the lower part of the vertical section 6 is downwards contracted to form a bottom air outlet 7, the bottom air outlet 7 extends downwards to the bottom of the casing pipe 2, the bottom air outlet 7 is of a necking structure, and air is prevented from entering the inner cavity of the casing pipe 2 or liquid is prevented from flowing out from the bottomThe air port 7 overflows to ensure the accuracy of the sampling amount of the capillary tube 3.
During actual processing, gasbag 1, connecting pipe 8, sleeve pipe 2 and reinforcement piece 4 are integrated into one piece structure, and the volume of sleeve pipe 2 is greater than the volume of gasbag 1, prevents that mixing in-process liquid from getting into gasbag 1.
The utility model discloses the hydrophilic modified coating of 3 internal surfaces of capillary can reduce the contact angle of liquid and 3 internal surfaces of capillary for 3 internal surfaces of capillary have very big hydrophilic performance, can know according to Young-Laplace equation simultaneously, and when 3 internal diameters of capillary are fixed, the contact angle is less, and the climbing volume is just bigger, therefore hydrophilic modified coating can improve the sampling speed, makes the collection liquid be full of capillary 3 fast, realizes quick sampling;
wherein the Young-Laplace equation is as follows:
；
wherein V is the climbing volume of the liquid in the circular capillary 3, r is the inner radius of the circular capillary 3, γ is the surface tension of the liquid, θ is the contact angle, Δ ρ is the density difference between the liquid and the gas, and g is the gravitational acceleration;
the inner diameter and the climbing volume of the capillary 3 of the utility model satisfy the Young-Laplace equation, and the equation shows that when the contact angle between the liquid and the inner surface of the capillary 3 is fixed, the larger the inner diameter of the capillary 3 is, the larger the climbing volume of the liquid is; the drop volume of the liquid drop at the opening of the capillary 3 is positively correlated with the outer diameter of the capillary 3, when the surface tension of the liquid is fixed, the larger the outer radius of the capillary 3 is, the larger the drop volume of the liquid drop is, and the specific relation between the drop volume of the liquid drop and the outer radius of the capillary 3 is as follows:
wherein the content of the first and second substances,Vin order to be the drop volume of the droplet,Ris the outer radius of the orifice of the capillary tube 3,γin order to be the surface tension of the liquid,ρthe density of the liquid is the density of the liquid,Fis a correction factor.
Therefore, during actual processing, the utility model discloses can make multiple different specifications with capillary 3 according to Young-Laplace equation, drop volume method, every specification corresponds an amount of collection such as 5 mu L, 10 mu L, 15 mu L, 20 mu L etc. to satisfy the quantitative collection demand of different amounts of collection.
The utility model discloses use the kit to detect as the example, the concrete description the working process of filling device is gathered to trace liquid:
1) selecting a trace liquid acquisition filler device with corresponding specification according to the requirements of the items to be detected;
2) inserting the lower part of a sleeve 2 into a sample tube, inserting a capillary tube 3 positioned outside the sleeve 2 into a sample, wherein a bottom air outlet 7 of an exhaust channel is positioned above the liquid level of the sample tube, liquid is quickly filled in the capillary tube 3 under the capillary action, the lower part of the sleeve 2 is inserted into the sample tube, the capillary tube 3 positioned outside the sleeve 2 is inserted into the sample, the bottom air outlet 7 of the exhaust channel is positioned above the liquid level of the sample tube, and the capillary tube 3 is quickly filled in the liquid under the capillary action;
3) inserting the capillary quantifying tube and the bottom exhaust port of the exhaust channel into the diluent, repeatedly extruding the air bag 1 to pump and mix the sample and the diluent, and extruding the air bag 1 to pump the sample diluent after mixing, wherein the pumping amount of the sample diluent is larger than the volume of the capillary 3;
4) and extruding the air bag 1, dripping the sample diluent into a sample hole of the kit, observing color change, and determining a detection result.
Claims (7)
1. The utility model provides a filling device is gathered to trace liquid, includes gasbag (1) and sleeve pipe (2) rather than the intercommunication, its characterized in that: a capillary tube (3) is fixedly inserted into the lower part of the sleeve (2), and the bottom of the capillary tube (3) extends outwards out of the sleeve (2); an exhaust assembly communicated with the sleeve (2) is arranged on the side wall of the sleeve (2) corresponding to the capillary (3), and the height of an air inlet at the top of the exhaust assembly is higher than that of a top pipe orifice of the capillary (3).
2. The micro liquid collection and filling device according to claim 1, wherein: the exhaust assembly comprises a reinforcing sheet (4) integrally formed with the sleeve (2), an exhaust channel with a broken line structure is arranged on the reinforcing sheet (4), and the height difference between the top air inlet of the exhaust channel and the top orifice of the capillary tube (3) is that of the exhaust channelΔHIs 1 mm-2 mm.
3. The trace liquid collecting and filling device according to claim 2, wherein the exhaust channel comprises an inclined section (5) communicated with the casing (2) and a vertical section (6) vertically extending downwards from the right end of the inclined section (5), an included angle α between the inclined section (5) and the casing (2) is 60-90 degrees, the lower part of the vertical section (6) is inwards folded downwards to form a bottom air outlet (7) in a truncated cone-shaped structure, and the bottom air outlet (7) extends downwards to the bottom of the casing (2).
4. The micro liquid collection and filling device according to claim 1, wherein: a length of capillary tube (3) extending out of the sleeve (2)L≥5 mm。
5. The micro liquid collection and filling device according to claim 1, wherein: the inner surface of the capillary tube (3) is coated with a hydrophilic surface modification coating.
6. The micro liquid collection and filling device according to claim 1, wherein: the air bag (1) is connected with the sleeve (2) into a whole through a connecting pipe (8), and the volume of the sleeve (2) is larger than that of the air bag (1).
7. The micro liquid collection and filling device according to claim 6, wherein: the connecting pipe (8) is of a round table-shaped structure with a large upper part and a small lower part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921572434.3U CN210700181U (en) | 2019-09-20 | 2019-09-20 | Trace liquid collecting and filling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921572434.3U CN210700181U (en) | 2019-09-20 | 2019-09-20 | Trace liquid collecting and filling device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210700181U true CN210700181U (en) | 2020-06-09 |
Family
ID=70941457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921572434.3U Active CN210700181U (en) | 2019-09-20 | 2019-09-20 | Trace liquid collecting and filling device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210700181U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110548553A (en) * | 2019-09-20 | 2019-12-10 | 安图实验仪器(郑州)有限公司 | Trace liquid collecting and filling device |
-
2019
- 2019-09-20 CN CN201921572434.3U patent/CN210700181U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110548553A (en) * | 2019-09-20 | 2019-12-10 | 安图实验仪器(郑州)有限公司 | Trace liquid collecting and filling device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5260030A (en) | Calibrated pipette tip and method | |
| US20090216465A1 (en) | System for measuring viscosity | |
| CN210700181U (en) | Trace liquid collecting and filling device | |
| CN108535504A (en) | A kind of trace liquid quantitative sampler and sampling loading methods | |
| CN110548553A (en) | Trace liquid collecting and filling device | |
| CN218496956U (en) | Quantitative acid adding instrument | |
| CN208420451U (en) | Chemical analysis tests dedicated auxiliary automatic liquid-suction device | |
| CN209173956U (en) | A kind of micropipettor | |
| CN207408157U (en) | A kind of micro liquid sampler | |
| CN205361385U (en) | With supporting pipettor that uses of pipette | |
| CN208140729U (en) | A kind of trace liquid quantitative sampler | |
| CN204744197U (en) | Novel micro - heparin tube of ration | |
| CN201016886Y (en) | Multifunctional filling injector | |
| CN206876422U (en) | Fluid sampling compound tube | |
| CN209432525U (en) | A kind of fluid sampling device | |
| CN207735020U (en) | A kind of use for laboratory multrirange charger | |
| CN214514660U (en) | Liquid transfer tube | |
| CN209722118U (en) | SdLDL-C assay kit | |
| CN210803002U (en) | Syringe type quick quantitative liquid sampling device | |
| CN205007990U (en) | Burette is absorb to trace | |
| CN207981212U (en) | Novel liquid-transfering device based on liquid-transfering gun | |
| CN217221534U (en) | Ear washing ball | |
| CN220803331U (en) | Continuous sample adding device | |
| CN201010507Y (en) | High-precision micropipette | |
| CN205216871U (en) | Small quantity sampling dropping tube |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |