KR20170046166A - Nozzle cap for specimen test container, and specimen test container and specimen test kit using same - Google Patents

Abstract

A nozzle cap for a sample test container and a sample test using the same, which are free from manufacturing troubles and released from the risk that the sample liquid is not filtered at the time of use due to the fall of the retaining member or the filter or the deviation of the filter Vessel and sample test kits are provided. The nozzle cap for a test container of the present invention can be connected to the open end of the container base to constitute a test container for a sample. A cap comprising: a nozzle body having a cap portion connectable with an open end of the container base and a nozzle tube for discharging the sample liquid from the drop port; And a filter accommodated in the nozzle body, wherein the nozzle body has a tubular filter accommodating portion inside the cap portion, and the filter has a plurality of ribs provided at the open end of the filter accommodating portion, In the filter accommodating portion.

Description

TECHNICAL FIELD The present invention relates to a nozzle cap for a sample test container, a sample test container using the nozzle cap, and a sample test kit using the nozzle cap. [0002]

The present invention relates to a nozzle cap for a sample test container, and a sample test container and a sample test kit using the same.

Simple test tests have been developed that can detect infections of pathogens such as viruses or germs, pregnancy status, blood glucose levels, etc. in a short time. Such a simplified test kit does not require any special equipment, and it is possible to make a measurement on a desired item at a low cost through a relatively simple operation.

In order to carry out such a test, for example, a part of excrement such as a collected liquid or a nasal discharge or a waste such as urine or feces collected from a patient's pharynx or nasal cavity is suspended in a buffer solution or the like in a specimen test container Prepare the sample solution. The analysis is performed by dropping the sample liquid in the sample container into a predetermined position of the test plate included in the kit. For example, in order to remove unnecessary substances in the sample liquid, Filtered. The performance of this filtration depends heavily on the performance of the analysis.

Here, an example of a conventional sample test container is shown. 9 is a diagram schematically showing an example of a sample test container included in a conventional sample test kit.

The conventional sample test container 900 includes a container base 920 for receiving the sample liquid and a nozzle cap 940 for filtering the sample liquid and discharging the sample liquid from the drop port 942. The container base 920 has a connecting portion 924 that is open at its upper side and is threaded on its outer surface. The connection portion 924 is set in a shape that can be screwed with a thread (not shown) provided on the inner surface of the cap 944 at the lower side of the nozzle cap 940. Both the container base 920 and the nozzle cap 940 are formed of a thermoplastic resin such as polypropylene.

10 is a view schematically showing the nozzle cap 940 constituting the conventional test sample container 900 shown in Fig. 9, wherein (a) is a longitudinal sectional view of the nozzle cap 940, and (b) Is a disassembled longitudinal cross-sectional view of the nozzle cap 940.

10A, the nozzle cap 940 is composed of a nozzle body 941 and a cap portion 944 having a nozzle pipe 943 communicating with the drop port 942. As shown in FIG. The lower end of the nozzle body 941 is integrally molded with the cap portion 944 and a proximal portion 948 of the cap portion 944 provided in a direction substantially perpendicular to the axial direction of the nozzle body 941 is provided with a cap portion 944 A filter 950 is fitted in a tubular filter accommodating portion 946 extending in a direction substantially perpendicular to the proximal portion 948 in the housing 944. The filter accommodating portion 946 also has an inner cap 960 fitted or screwed from the outside and an inner wall 964 of the filter accommodating portion 946 and the inner cap 960 is fixed have. The lower end of the inner cap 960 is provided with a filter hole 962 designed to be slightly smaller than the outer diameter of the filter 950. The filter 950 is sandwiched and fixed to the proximal end 948 in the nozzle cap 940, the filter accommodating portion 946 and the inner cap 960. [ The sample liquid in the sample test container passes from the filter hole 962 through the filter 950 and the nozzle pipe 943 and flows outward through the drop port 942 to the outside, (Droplets).

However, some problems remain in such a conventional sample test container 900. For example, as shown in Fig. 10B, since the inner cap 960 is required as a holding member in addition to the filter 950, only the nozzle cap 940 is used as at least three members It is a point that needs to be configured. Also, for example, since the outer circumference of the filter 950 is held by the inner cap 960 of the holding member. It is necessary to avoid the risk that the specimen liquid is used for measurement without being filtered at the time of use due to the detachment of the inner cap 960 and / or the filter 950 or the displacement of the filter 950.

An object of the present invention is to solve the above problem, and it is an object of the present invention to solve the above-mentioned problem, and to provide a method for measuring a sample solution, And a sample test container using the nozzle cap and a sample test kit using the nozzle cap.

The present invention relates to a nozzle cap which can be connected to an open end of a container base to constitute a sample test container,

A nozzle body having a cap portion connectable with the open end of the container base and a nozzle pipe for discharging the sample liquid from the drop port; And

And a filter accommodated in the nozzle body,

here,

The nozzle body has a tubular filter accommodating portion inside the cap portion, and

And the filter is accommodated and held in the filter accommodating portion by folding of a plurality of ribs provided at the open end of the filter accommodating portion.

In one embodiment, the plurality of ribs are provided so as to be substantially equally spaced on the open end of the filter accommodating portion.

In one embodiment, the number of the plurality of ribs is 2 to 16.

In one embodiment, the nozzle body is made of a thermoplastic resin.

In another embodiment, retention of the filter by folding of the plurality of ribs is performed by ultrasonic treatment.

The present invention is also a container for accommodating a specimen liquid for performing a specimen test, wherein the nozzle cap; And a container base for receiving the sample liquid.

The present invention also relates to a container for containing the specimen liquid,

And a test plate for analyzing the characteristics of the object to be measured contained in the sample liquid.

In one embodiment, the specimen test kit of the present invention further includes a collection tool for collecting the specimen.

According to the present invention, it is possible to solve the problem from the manufacturing complexity and to reduce the manufacturing cost. According to the present invention, for example, the specimen liquid is not filtered at the time of use and is released from the risk, which is used for the measurement, due to the detachment of the retention member or the filter or the displacement of the filter. It is also possible to avoid the unnecessary matter in the sample liquid from being mistakenly dropped on the test plate of the specimen sample kit. This makes it possible to detect the object to be measured more accurately in a short period of time.

Fig. 1 is a schematic cross-sectional view of the cap shown in Fig. 1 for explaining an example of a nozzle cap according to the present invention.
2 is a bottom view of the nozzle cap of the present invention shown in Fig.
Fig. 3 is a schematic view of a nozzle cap constituting a test container of the present invention, and is a cross-sectional view of the nozzle cap and the filter for explaining a state before the filter is attached.
Fig. 4 is a schematic bottom view of the nozzle cap before attaching the filter shown in Fig. 3; Fig.
Fig. 5 is a view schematically showing some examples of the shapes of the ribs provided in the nozzle cap before attaching the filter shown in Fig. 3;
(A) is a front view of the sample test container after the nozzle cap shown in Fig. 1 is attached to the base portion of the container, Fig. 6 (b) is a front view of the sample test container, Fig. 10 is a front view of the sample test container for explaining an example of a state before the nozzle cap is attached to the base;
Fig. 7 is a cross-sectional view of the test container of the present invention shown in Fig. 6 (b), schematically showing the cross section of each of the container base and the nozzle cap. Fig.
Fig. 8 is a view showing an example of a specimen test kit of the present invention, wherein (a) is a diagram schematically showing a state in which the specimen collected is added to a dilution liquid of a container base, (b) (C) is a view schematically showing a state in which the sample solution filtered through the sample container of (b) is dropped onto the bottom of the desired test plate .
9 is a diagram schematically showing an example of a sample test container included in a conventional sample test kit.
Fig. 10 is a view schematically showing a nozzle cap constituting a conventional sample test container shown in Fig. 9, wherein (a) is a longitudinal sectional view of the nozzle cap, and (b) is an exploded longitudinal sectional view of the nozzle cap .

Hereinafter, the present invention will be described with reference to the drawings.

(Nozzle cap for sample test container)

The nozzle cap (hereinafter referred to as " nozzle cap ") for a test container of the present invention can be connected to the open end of the container base to constitute a test container for a sample. Here, the term " sample test container " used in the present specification refers to a container for receiving various sample liquid samples for performing sample test.

Fig. 1 is a schematic cross-sectional view of the cap shown in Fig. 1 for explaining an example of a nozzle cap according to the present invention.

As shown in FIG. 1, the nozzle cap 140 of the present invention includes a nozzle body 141 and a filter 150. The nozzle body 141 is composed of a nozzle tube 143 and a cap portion 144. In the present invention, it is preferable that the nozzle tube 143 and the cap portion 144 are integrally formed for the purpose of solving the complicated manufacturing process.

The nozzle tube 143 has an inlet port 142 for discharging (for example, dropping) the filtered sample liquid. The nozzle tube 143 has, for example, a taper shape such that the diameter thereof increases from the upper side to the lower side of the drawing. The lower end of the nozzle tube 143 may be in contact with the filter 150, or may be disposed at a predetermined interval. The shape of the dropping port 142 is not necessarily limited, but is, for example, circular, and its outer diameter is preferably 1 mm to 5 mm, and more preferably 2 mm to 4 mm. The length of the nozzle tube 143 is preferably 8 mm to 20 mm, more preferably 10 mm to 15 mm.

A tubular filter accommodating portion 146 extending in the axial direction of the nozzle tube 143 (for example, substantially parallel to the axial direction of the nozzle tube 143) is provided inside the cap portion 144 Lt; / RTI > The filter accommodating portion 146 preferably has a cylindrical shape. This allows the sample liquid in the sample test container to flow from the filter accommodating portion 146 through the nozzle pipe 143 to the dropping port 142 (142), the nozzle pipe 143, and the filter accommodating portion 146, ). ≪ / RTI > Further, a filter 150 is accommodated in the filter accommodating portion 146. The inner diameter of the filter accommodating portion 146 is preferably designed to coincide with the outer diameter of the filter to be used or to be slightly smaller than the outer diameter of the filter. The inner diameter of the filter accommodating portion 146 is, for example, 2 mm to 15 mm, preferably 4 mm to 12 m. The filter accommodating portion 146 is also preferably designed to be slightly reduced in diameter toward the upper side of the drawing (that is, the side on which the nozzle tube 143 is provided). So that the adhesion between the filter 150 and the inner wall of the filter accommodating portion 146 is further improved.

The filter 150 is accommodated and held in the filter accommodating portion 146 by folding of a plurality of ribs 149 provided at the open end 147 of the filter accommodating portion 146. That is, in one embodiment of the present invention, the plurality of ribs 149 are formed integrally with the filter accommodating portion 146 at the open end 147 side of the filter accommodating portion 146, The filter 150 is accommodated and held in the filter accommodating portion 146 by the plurality of ribs 149 by the end portion of the filter accommodating portion 146 being oriented in the direction of the central axis of the filter accommodating portion 146. [ As used herein, the term " folding of a plurality of ribs " means that a plurality of ribs integrally formed with the filter accommodating portion are provided in the direction of the central axis of the filter accommodating portion 146 For example, at an angle of approximately 90 [deg.]); And a state in which all or a part of the plurality of lips molded integrally with the filter accommodating portion melts and forms a convex portion toward the central axis direction of the filter accommodating portion (for example, a plurality of lips are melted, Holding the filter); And a state in which these are combined. In the present invention, the filter 150 includes a filter accommodating portion 146, a plurality of ribs 149, and the other end (the end opposite to the dropping port 142) of the nozzle body 141 in the nozzle pipe 143, It is preferable that the filter 150 is fixed between the base end 148 of the cap part 144 and the filter 150. The filter 150 and the filter accommodating part 146, the plurality of ribs 149, It is more preferable that the gap is not in contact with the outer circumferential surface 148,

2 is a bottom view of the nozzle cap of the present invention shown in Fig.

In the nozzle cap 140, the plurality of ribs 149 are preferably arranged to be substantially equally spaced above the open end 146 of the filter housing 146. In the present invention, since the ribs 149 are folded toward the center of the filter accommodating portion 146 in a state where the ribs 149 are arranged around the filter 150 at substantially equal intervals, So that the stability of the filter 150 in the filter accommodating portion 146 can be enhanced. In the present invention, the number of ribs 149 provided in one nozzle cap 140 is not necessarily limited as long as it does not interfere with each other due to folding, but is preferably 2 to 16. There is a possibility that the number of the ribs 149 is not sufficient to hold the filter 150 and the stability of the filter 150 in the filter accommodating portion 146 may not be maintained. If the number of ribs 149 exceeds 16, adjacent ribs interfere with each other to interfere with the retention of the filter 150, as a result of which the periphery of the filter 150 becomes more lip 149 Is covered. The filtration area of the filter 150 is decreased, so that the filtration efficiency may be lowered.

The nozzle cap 140 of the present invention is preferably made of, for example, a transparent material so that the content of the sample sample liquid can be visually confirmed from the outside. The nozzle cap 140 is preferably made of a plastic material such as thermoplastic resin.

Examples of the thermoplastic resin include, but are not necessarily limited to, polypropylene, polyethylene, polyvinyl chloride, polyethylene terephthalate, and polystyrene. Polyethylene or polypropylene is preferable in that it is excellent in chemical resistance and versatility. In the present invention, the nozzle cap 140 can be molded by injection molding, for example, by using the thermoplastic resin as described above, and the fixation of the filter 150 by the plurality of ribs 149, For example, by ultrasonic treatment as described below.

The material of the filter 150 accommodated in the nozzle cap 140 is not particularly limited, and a filter material employed in a specimen test container included in a conventional inspection test kit may be used.

The filter material is, for example, a material that can be used for microfiltration. Examples of the filter material include inorganic fibers such as cellulose, glass fiber, silica fiber, nitrocellulose, cellulose ester, polyethersulfone, polysulfone, ethylene tetrafluoride resin, vinylidene fluoride resin, polycarbonate, polypropylene, polyamide, Polyester. Cotton, and stainless steel fibers, and combinations thereof. The thickness of the filter 150 is not particularly limited, and any thickness can be selected by those skilled in the art.

Fig. 3 is a schematic view of a nozzle cap constituting a test container of the present invention, and is a cross-sectional view of the nozzle cap and the filter for explaining a state before the filter is attached.

The nozzle cap 240 before the filter is attached is provided with a drop port 242, a nozzle tube 243, and a filter accommodating portion 246 by injection molding in advance. The lip 249 is provided on the open end 247 of the filter accommodating portion 246 along the axial direction of the nozzle tube 243 (i.e., in a direction substantially parallel to the axial direction of the nozzle tube 243). It is preferable that the open end 247 of the filter accommodating portion 246 has a plane that is substantially perpendicular to the lip 249 (i.e., a direction orthogonal to the axial direction of the nozzle tube 243).

4 is a schematic bottom view of the nozzle cap 240 shown in Fig.

At the bottom surface of the nozzle cap 240, the proximal end 248 has a substantially flat surface in the direction perpendicular to the axial direction of the nozzle tube 243, for example, Can be more appropriately fixed. The proximal end 248 is provided with a plurality of grooves 252 from the periphery of the filter accommodating portion 246 toward the end of the nozzle pipe 243 at the center. The test liquid that has been filtered through the filter from the container base collects in the nozzle tube 243 through these grooves 252 and is discharged outside from the drop port 242. In FIG. 4, a structure is shown in which the proximal end 248 is flat so as to be in close contact with the filter, and the groove 252 is appropriately provided. However, the present invention is not necessarily limited to this. For example, the portion corresponding to the proximal portion 248 may be inclined toward the nozzle tube 243, and a portion corresponding to the one groove 252 may be formed as a rib so as to contact and fix the filter.

Fig. 5 is a diagram schematically showing some examples of the shape of the lip provided on the nozzle cap before the filter shown in Fig. 3 is attached.

Fig. 5 (a) is an enlarged view of the lip 249 enclosed by a broken line in Fig. 3. It is preferable that the ribs 249 are formed so as to have an appropriately rounded shape in advance in order to prevent interference due to overlapping with adjacent ribs when holding the filter. The width (W ₁ ) and length (L ₁ ) of the lip 249 may be selected by the person skilled in the art depending on the size (e.g., diameter) of the filter to be used. For example, in the case of using a filter having a diameter of 7 mm, the width W ₁ of the lip 249 is preferably ₁ mm to 3 mm. The length L ₁ of the lip 249 is preferably ₁ mm to 3.5 mm. In the present invention, the shape of the lip 249 is not limited to the shape shown in Fig. 5A. For example, the lip 249 may have any shape as shown in Figs. 5B to 5D . 5 (b) is an example of a lip 261 having a semicircular end, (c) is an example of a lip 262 having a trapezoidal shape shortened toward the end, and (d) Is an example of a lip 263 having a substantially parallelogram shape.

Referring again to FIG. 3, the filter 150 is inserted into the filter accommodating portion 246 provided with the plurality of ribs 249 until the end thereof abuts against the base portion 248. Thereafter, the lip 249 of the filter accommodating portion 246 is subjected to ultrasonic treatment, for example, and each lip 249 is folded to hold the filter 150. This ultrasonic treatment is carried out using means known to those skilled in the art, and the specific conditions necessary for the ultrasonic treatment can be appropriately selected by those skilled in the art. The ultrasound treatment refers to, for example, an operation of melting a thermoplastic resin by applying ultrasonic vibration when the lip 249 is made of the thermoplastic resin.

Thereby, the filter 150 can be surely received and fixed in the filter accommodating portion 246 by only the nozzle cap 240 without using the retaining member, for example, by the detachment of the retaining member or the filter or the deviation of the filter , The sample liquid is not filtered at the time of use and the risk of measurement can be eliminated.

(Sample test container)

Fig. 6 is a diagram schematically showing an example of a test container of the present invention. Fig. 6 (a) is a front view of the test container of the sample after the nozzle cap shown in Fig. 1 is attached to the container base, Fig. 10 is a front view of the sample test container for explaining an example of a state before the nozzle cap is attached to the base;

6 (a), the sample test container 100 of the present invention includes a container base 120 and a nozzle cap 140 for accommodating a sample liquid. The container base 120 and the nozzle cap 140 are combined with each other as shown in Figure 6 (a). Further, the container base 120 is not particularly limited as long as it can be attached to the nozzle cap 140.

6B is a front view of the sample test container 100 of the present invention for explaining an example of a state before the nozzle cap 140 is attached to the container base 120. Fig. For example, the container base 120 may have a tapered shape so as to be slightly reduced in diameter toward the cylinder or downward, and may contain, for example, 0.1 mL to 2 mL, preferably 0.4 mL to 1 mL of the sample solution have. The container base 120 also has a connection 124 having an opening on its upper side and a threaded exterior surface. The connection portion 124 is set in a shape that can be screwed with a thread (not shown) provided on the inner surface of the cap portion 144 below the nozzle cap 140.

Fig. 7 is a cross-sectional view of the sample test container of the present invention shown in Fig. 6 (b), schematically showing the cross section of each of the container base and the nozzle cap. Fig.

7, in the sample test container 100 of the present invention, the container base 120 and the nozzle cap 140 are formed by, for example, a screw provided in the connection portion 124 of the container base 120, And can be attached and detached by screwing with a thread of a connection portion 145 provided on the inner surface of the cap portion 144 of the cap 140. When the nozzle cap 140 is attached to the container base 120, it is possible to prevent the sample liquid contained in the container 100 from leaking from the attachment portion, It is preferable that sufficient adhesion is maintained between the connection portion 124 of the base portion 120 and the connection portion 145 of the nozzle cap 140. [

In this embodiment, as described above, the fixing style of the container base 120 and the nozzle cap 140 is an example in which the connection between the connection part 124 and the connection part 145 is screwed. However, It is not limited to this form. For example, the container base 120 and the nozzle cap 140 may be fitted and fixed by a snap fit.

In the sample test container 100 of the present invention, the container base 120 is also preferably made of, for example, a transparent material so that the content of the sample sample liquid can be visually confirmed from the outside. In addition, the container base 120 is also preferably made of a plastic material such as thermoplastic resin, for example, the same as the nozzle cap described above.

In the sample test container of the present invention, for example, when the container base is made of a thermoplastic resin, the container base can also be molded by injection molding.

In the specimen container of the present invention, for example, a specimen collected through a sampling mechanism such as a swab is added to a diluent such as a buffer solution in the container base, and these specimens are mixed to prepare a specimen solution. In the present invention, the diluted solution may be preliminarily added to the container base and the opening may be sealed with an aluminum sheet or the like at the time of use, and a specimen may be added thereto. Thereafter, the nozzle cap is tightly coupled to the container base by, for example, a screw connection. The sample solution thus prepared is dropped onto the test plate contained in the sample test kit, for example, through a drop outlet.

Examples of the sample that can be contained in the test container of the present invention include a sample solution such as a nasal solution and a pharynx; Feces such as runny nose, sputum, stool, urine; blood; group; And cells. Examples of the analyte contained in the specimen include, but are not limited to, influenza virus, respiratory syncytial virus (RS), adenovirus, hemolytic streptococcus group A, pneumococcal pneumoniae, legionella, human metanomovirus, A peptide hormone, a steroid, a physiologically active amine, a vitamin, a prostaglandin, a tetracycline, etc., such as a microorganism of a hospital such as a virus, a sapovirus, a diarrhea adenovirus, Antibiotics, toxins produced by bacteria and the like, various tumor markers, pesticides, and nucleotides complementary to nucleic acid components derived from the above-mentioned pathogenic microorganisms, clinical markers, allergens such as foods and the like.

The sample test container of the present invention can reliably receive and fix the filter without using the holding member, for example, by removing the holding member or the filter or by shifting the filter, the sample sample is not filtered during use It is a specimen test container that can eliminate the risk of

(Sample test kit)

The specimen test kit of the present invention includes a container for accommodating the specimen solution and a test plate for analyzing characteristics of the specimen contained in the specimen specimen.

The test plate constituting the present invention contains, for example, a capturing substance and a detection reagent, and may be, for example, a plate of immunochromatography known in the art.

For example, when the sample is a bacterium, a virus, a hormone, or other clinical marker, the capturing substance may be an antibody (for example, a polyclonal antibody and a monoclonal antibody) . Such trapping material can be immobilized on a predetermined membrane surface provided on a test plate in a manner known to a person skilled in the art. The immobilization of the capturing material on the membrane is carried out, for example, by adsorbing a solution of the capturing material in a buffer or the like onto the membrane and then drying. The trapping material may be immobilized, for example, in a line shape, in a test plate.

For example, when the test kit of the present invention is used as a kit for diagnosing the pathogenesis of adenovirus and RS virus, anti-adenovirus antibody or anti-RS virus antibody is immobilized on the test plate as a capturing substance . Alternatively, for example, when the test kit of the present invention is used as a detection kit for detecting an allergic substance such as a clinical marker or food, the test plate may contain an antibody against the clinical marker or the allergic substance Is fixed. The type of antibody that can be immobilized on one test plate is not particularly limited, and one or more antibodies may be immobilized.

The detection reagent is capable of specifically binding to the analyte to form a complex with the analyte. For example, when the substance to be measured is an antigenic substance such as a virus, the detection reagent is an antibody against the virus, and the labeled antibody is exemplified. Examples of antibodies prior to labeling are the same as those that can be used for the capture reagent. Examples of the substance used for labeling include enzymes, fluorescent and chemiluminescent labels, magnetic substance labels, radioactive isotopes, gold colloids, beads, and colored latex.

Such a detection reagent is preliminarily embedded in a test plate by a method known to a person skilled in the art. For example, when the test kit of the present invention is used as a kit for diagnosing adenovirus or RS virus infection, the test plate may be coated with gold colloid-labeled anti-adenovirus antibody or gold-colloid-labeled anti-RS virus antibody . Alternatively, for example, when the test kit of the present invention is used as a detection kit for detecting an allergic substance such as a clinical marker or food or the like, the test plate may be used as a detection reagent for the clinical marker or the allergic substance Antibody is built in. Whether or not to provide one or a plurality of measurement items in one test plate is not limited.

In the specimen test kit of the present invention, the detection reagent may be added to the test plate after the specimen test solution is added instead of being embedded in the test plate in advance.

The specimen test kit of the present invention may further include a collecting tool for collecting the specimen. Examples of such harvesting tools include swabs, harvesting tools, harvesting vessels, brushes and the like. It is preferable that the collecting tool is sterilized. The specimen test kit of the present invention may further contain, for example, a reaction stopping solution for stopping the reaction between the enzyme and the substrate, if necessary. Examples of the reaction stopping solution include citric acid, sulfuric acid, and the like. In addition, the specimen test kit of the present invention may include a handling manual and the like as necessary.

Next, as an example of a method of using the specimen test kit of the present invention, an example of a use method when the kit is an influenza kit and the specimen is a nasal solution is described.

First, as shown in FIG. 8A, a swab 410 (collecting tool), which polishes a nasal cavity of a subject in a predetermined manner, for example, is immersed in a container base 120 containing a buffer solution 412 do. Thereafter, the swab 410 is moved up and down in the buffer solution 10 times or more, for example, and finally swept away. Thus, the sample liquid is prepared in the container base 120. Next, as shown in FIG. 8B, the container base 120 and the nozzle cap 140 are firmly screwed in a state in which the sample liquid 420 is held in the container base 120 . 8 (c), the container base 120 is pushed by both sides, and the sample liquid (not shown) filtered from the drop port 142 of the sample test container 100 through a filter A predetermined amount (for example, 3 drops) of the test plate 422 is dropped onto the red lower portion 432 of the test plate 430. Thereafter, the test plate 430 is left as it is, and the display window 434 of the test plate 430 is visually judged by physicians after a predetermined time has elapsed. Through a predetermined line displayed on the display window 434, the doctors can detect positive or negative for various influenza viruses (e.g., positive for influenza A virus antigen, positive for influenza B virus antigen, influenza A virus antigen, A positive test for both of the influenza B virus antigens and a negative test for neither the influenza A virus antigen nor the influenza B virus antigen can be performed.

The present invention is useful, for example, in the medical field where rapid and efficient simple examination is required without deteriorating the sensitivity and performance of the analysis.

100 sample test container
120 container donation
140, 240 nozzle cap
141 nozzle body
142, 242
143, 243 Nozzle tube
144 cap portion
146, 246 filter accommodating portion
147, 247 open end
148, 248,
149, 249 Lip
150 filters
252 home
410 cotton swabs
412 buffer
420 Sample liquid
422 The filtered specimen liquid
430 test plate
432 Red bottom
434 display window

Claims (8)

A nozzle cap connected to an open end of the container base to constitute a sample test container,
A nozzle body having a cap portion connectable with the open end of the container base and a nozzle pipe for discharging the sample liquid from the drop port; And
And a filter accommodated in the nozzle body,
Here, the nozzle body has a cylindrical filter accommodating portion inside the cap portion, and
Wherein the filter is accommodated and held in the filter accommodating portion by folding of a plurality of ribs provided at the open end of the filter accommodating portion. The nozzle cap according to claim 1, wherein the plurality of ribs are provided so as to be substantially equally spaced on the open end of the filter accommodating portion. 3. The nozzle cap according to claim 1 or 2, wherein the number of the plurality of lips is two to sixteen. The nozzle cap according to any one of claims 1 to 3, wherein the nozzle body is made of a thermoplastic resin. The nozzle cap according to claim 4, wherein retention of the filter by folding of the plurality of ribs is performed by ultrasonic treatment. As a container for receiving a specimen liquid for performing a specimen test,
A nozzle cap according to any one of claims 1 to 5, And
And a container base for receiving the sample liquid. A container for containing the specimen liquid according to claim 6;
And a test plate for analyzing characteristics of the object to be measured contained in the specimen sample liquid. The kit according to claim 7, further comprising a collecting tool for collecting the specimen.

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