CN218739765U - Atomizing pipe convenient to assembly - Google Patents

Atomizing pipe convenient to assembly Download PDF

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Publication number
CN218739765U
CN218739765U CN202123142046.1U CN202123142046U CN218739765U CN 218739765 U CN218739765 U CN 218739765U CN 202123142046 U CN202123142046 U CN 202123142046U CN 218739765 U CN218739765 U CN 218739765U
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China
Prior art keywords
chip
tube
catheter
section
channel
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CN202123142046.1U
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Chinese (zh)
Inventor
徐宏
王茂强
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Hangzhou Kunbo Biotechnology Co Ltd
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Hangzhou Kunbo Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/002Particle size control by flow deviation causing inertial separation of transported particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3368Temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1025Respiratory system
    • A61M2210/1035Bronchi

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Nozzles (AREA)

Abstract

The application discloses an atomization catheter convenient to assemble, which comprises a catheter body, wherein one end of the catheter body is a near end, the other end of the catheter body is a far end capable of extending into a bronchus, a channel capable of conveying fluid from the near end to the far end is arranged inside the catheter body, an atomization head is arranged at the far end of the catheter body, and the fluid in the channel is atomized by the atomization head and then is output; a micro-channel chip is arranged in the atomizing head, and the fluid is atomized through the micro-channel chip; the far end of the tube body is of an open structure and is covered with a shell, the shell is provided with a spray nozzle, the tube body and the shell enclose a cavity, and the micro-channel chip is fixed in the cavity. The utility model provides an atomizing pipe assembly compact structure, the diameter is thinner, can go deep into the unable lung section that gets into of endoscope and carry out accurate atomizing and dose, and through targeting atomizing and dose, the drug effect is used in patient affected part more fast more accurately, avoids the liquid medicine to remain in oral cavity, nasal cavity.

Description

Atomizing pipe convenient to assembly
Technical Field
The present application relates to the field of medical devices, and in particular to an easily assembled nebulizing catheter that can be used for the treatment of bronchial diseases.
Background
When the treatment is performed under a clinical endoscope, an atomization administration mode is usually needed to be matched, so that injected medicine liquid can be uniformly distributed, the uniformity degree of the combination of related tissues (such as bronchial mucosa and gastrointestinal mucosa) and medicines is improved, and the impact injury possibly caused by the traditional direct injection to the tissues is reduced to the maximum extent.
The existing nebulizers are used for administering drugs by inhalation, and liquid drugs are decomposed into aerosol of fine particles or droplets, so that the patients using the drugs can inhale and absorb the drug more efficiently.
The internal part that current atomizing equipment can directly be dosed is limited, and atomizing equipment's the tip of dosing is difficult for the assembly because the volume is narrow and small, is difficult to carry out the target administration to small-area focus, and therapeutic effect needs further improvement.
SUMMERY OF THE UTILITY MODEL
The application provides an atomizing pipe that can intervene in the bronchus and release treatment material, the assembly of being convenient for, it is narrow and small to administer the tip volume, can target the medicine administration to the small size focus.
The application provides an atomizing catheter convenient to assemble, which comprises a catheter body, wherein one end of the catheter body is a near end, the other end of the catheter body is a far end capable of extending into a bronchus, a channel capable of conveying fluid from the near end to the far end is arranged in the catheter body, an atomizing head is arranged at the far end of the catheter body, and the fluid in the channel is output after being atomized by the atomizing head;
a micro-channel chip is arranged in the atomizing head, and the fluid is atomized by the micro-channel chip;
the far end of the tube body is of an open structure and is covered with a shell, the shell is provided with a spray nozzle, the tube body and the shell form a cavity in an enclosing mode, and the micro-channel chip is fixed in the cavity.
The application provides an atomizing pipe compares with traditional atomizer, and the body external diameter is littleer, and has certain flexibility, can get into the lung deep, and accurate dosing.
Depending on the nature of the therapeutic substance, the fluid itself may be in the liquid or gas phase, or a more complex mixture, and the atomization is intended to further disperse the fluid into smaller particles to facilitate absorption and uniform administration.
The shell is arranged at the far end of the tube body, and the micro-channel chip is fixed in a cavity channel formed by the shell and the tube body, so that the assembly is facilitated and the spraying state of the fluid at the atomizing port is controlled.
Several alternatives are provided below, but not as an additional limitation to the above general solution, but merely as a further addition or preference, each alternative may be combined individually for the above general solution or between several alternatives without technical or logical contradictions.
Optionally, the micro flow channel chip is mounted in the housing through a chip support, and the chip support is fixed to the housing by at least one of welding, bonding, and interference fit.
The chip support is fixed with the shell and used for limiting the position of the micro-channel chip, and the micro-channel chip and the chip support can be fixed in a bonding mode.
Optionally, the chip holder has a through region along the axial direction of the tube, and the microchannel chip is mounted in the through region.
The through region is used for fluid to pass through and yielding the micro-channel chip, and the micro-channel chip enters the chip support through the through region and is fixed with the chip support.
Optionally, the chip support is provided with a radial hollow area, the chip support forms a near-end socket and a far-end socket on two axial sides of the hollow area, and the near-end and the far-end of the microchannel chip are respectively inserted into corresponding sockets on the chip support.
The hollowed-out area can further reduce weight and improve the compliance of the chip support, the near end of the micro-channel chip is located at the near-end socket of the chip support, and the far end of the micro-channel chip is located at the far-end socket of the chip support.
Optionally, the tube body is butted with the micro flow channel chip through a connecting sleeve, and a distal end of the connecting sleeve is inserted into a proximal end of the chip support and is butted against or has a gap with the micro flow channel chip inside the chip support.
The pipe body is fixedly inserted to the near end of the connecting sleeve, the far end of the connecting sleeve is relatively abutted against and butted with the micro-channel chip, the micro-channel chip is positioned through the connecting sleeve, or when the micro-channel chip is fixedly connected with the chip support, the micro-channel chip is positioned without the connecting sleeve, and the bonding operation between the micro-channel chip and the chip support can be conveniently realized through the gap between the micro-channel chip and the connecting sleeve.
Optionally, the tube body includes an inner tube and an outer tube which are nested with each other, a lumen of the inner tube serves as a channel for conveying fluid, and the connecting sleeve is of a multi-section structure in the axial direction and is respectively connected with the inner tube, the outer tube and the chip support in a matching manner.
The connecting sleeve has different peripheral shapes and/or sizes between the ascending multistage of circumference, can constitute the stair structure between adjacent section, and it is spacing to be convenient for the axial to offset with adjacent other parts.
Optionally, the connecting sleeve is of an internal hollow structure, the axial middle part of the connecting sleeve is provided with a positioning shaft shoulder matched with the outer pipe, the positioning shaft shoulder forms a main body section in a multi-section structure, and the far end of the outer pipe is fixedly sleeved on the periphery of the main body section.
The positioning shaft shoulder is approximately cylindrical, and the far end of the outer tube is fixedly sleeved on the periphery of the main body section and can be fixed by adopting a bonding mode and the like.
Optionally, the distal end of the outer tube is inserted into the housing, and the housing and the outer tube enclose the chip support, the connecting sleeve and the microchannel chip.
The outer tube is bonded with the shell by glue, and the chip support, the connecting sleeve and the micro-channel chip are packaged inside the shell and the outer tube to form a closed fluid conveying space.
Optionally, two axial ends of the main body section of the connecting sleeve are respectively a proximal end butt joint section and a distal end butt joint section, wherein the distal end butt joint section is inserted into the proximal end socket of the chip holder, and the cross section of the distal end butt joint section is matched with the shape of the proximal end socket of the chip holder.
In order to facilitate positioning and limit relative rotation, the cross section of the far end butt joint section is non-circular, and the far end butt joint section and the chip support can be fixed by bonding or welding.
Optionally, the inner tube is inserted and fixed to the proximal end abutting section of the connecting sleeve, and the inner tube is fixedly connected with the inner wall of the proximal end abutting section.
When fluid enters the connecting sleeve through the inner pipe, the fluid cannot suffer from remarkable resistance, so that the smooth flowing is ensured.
The utility model provides an atomizing pipe convenient assembling, the first compact structure of atomizing, the diameter is thinner, can go deep into the unable lung section that gets into of endoscope and carry out accurate atomizing and dose, and through the atomizing of target dosing, the drug effect is used in patient affected part more fast more accurately, avoids the liquid medicine to remain in oral cavity, nasal cavity.
Drawings
FIG. 1 is a schematic view of an embodiment of an atomization conduit;
FIG. 2 is a schematic view of the proximal fitting portion of FIG. 1;
FIG. 3 is an exploded view of the tube of FIG. 2;
FIG. 4 is a schematic view of the internal structure of the pipe joint portion of FIG. 2;
FIG. 5 is a schematic view of the distal atomizing head of FIG. 1;
FIG. 6 is a schematic view of the atomizing head of FIG. 5 with the housing omitted;
FIG. 7 is an exploded view of an atomizing head portion according to an embodiment of the present application;
FIG. 8 is a schematic view of the atomizing head of FIG. 7 at another angle;
FIG. 9 is a schematic view of the internal structure of the atomizing head of FIG. 7;
FIG. 10 is a schematic view of a micro flow channel chip in an atomizing conduit according to an embodiment of the present application.
The reference numbers in the figures are as follows:
100. a tube body; 110. an outer tube; 120. an inner tube;
200. a pipe joint;
300. an atomizing head; 310. connecting sleeves; 311. a main body section; 312. a proximal end docking section; 313. a distal docking section; 320. a micro flow channel chip; 321. an inlet; 322. a first spacer; 323. a second spacer; 324. a pressurizing flow channel; 325. a third spacer; 326. a distribution member; 327. a flow guide member; 328. an outlet; 329. a flow guide column; 330. a chip holder; 331. a hollow-out area; 332. a proximal socket; 333. a distal socket; 340. a housing; 341. a spray nozzle; h1, a flow splitting section; h2, a pressurizing section; h3, and an atomization section.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
It will be understood that when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. When a component is referred to as being "disposed on" another component, it can be directly on the other component or intervening components may also be present.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description of the present application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
In the existing oral or nasal cavity atomization administration mode, because the airway of a human body is very long, atomized particles hardly reach the far end of the lung, most of the atomized particles are deposited at the oral or nasal cavity and the main bronchus, and accurate administration cannot be performed; in addition, the medicine cannot be deeply administrated into the air passage due to the size limitation of the equipment, and the treatment effect is poor, and improvement is needed.
Referring to fig. 1, in an embodiment of the present application, an atomizing catheter is provided, which includes a tube 100, one end of the tube 100 is a proximal end, and the other end is a distal end capable of extending into a bronchus, a channel capable of conveying a fluid from the proximal end to the distal end is provided inside the tube 100, an atomizing head is provided at the distal end of the tube 100, and the fluid in the channel is output after being atomized by the atomizing head.
The atomizing catheter of this embodiment compares with traditional atomizer, and body 100 external diameter is littleer, and has certain flexibility, can get into the deep of lung, and accurate dosing. The outer diameter, length, etc. of the tube 100 are not critical, but at least can extend into the bronchi to reach the lesion site, and preferred embodiments are provided below to achieve better results.
Depending on the nature of the therapeutic substance, the fluid itself may be in the liquid or gas phase, or a more complex mixing system, and atomization is intended to further disperse the fluid into smaller particles to facilitate absorption and uniform administration.
The tube body 100 may be made of metal or composite material, which provides necessary mechanical properties and intervention safety, and may be in the form of a single tube, multiple tubes, etc. according to the requirement of fluid delivery, when multiple tubes are used, at least two tubes may be arranged side by side or nested inside and outside, and each tube may be configured independently or as an integrated multi-lumen tube.
In this embodiment, the tubular body 100 includes an inner tube 120 and an outer tube 110 nested within each other, wherein the lumen of the inner tube 120 serves as a passage for transporting a fluid.
The outer tube 110 is located at the periphery of the inner tube 120 to provide protection and necessary mechanical support, the adapter 200 can be fixedly mounted at the proximal end of the outer tube 110, the proximal end of the inner tube 120 extends to the adapter 200 and is communicated with the adapter 200, the distal end of the inner tube 120 is communicated with the atomizing head, and the fluid is delivered into the inner tube 120 through the adapter 200 and is delivered to the distal end until the fluid is atomized at the atomizing head and then is delivered to the lesion.
The fitting 200 (e.g., luer fitting) and the body 100 may be bonded, interference fit, welded, etc., and in one embodiment, the fitting 200 is adhesively secured (e.g., by UV glue curing) to the inner tube 120 and the outer tube 110.
In order to facilitate the passage in the thinner bronchus, the outer diameter of the tube body 100 is generally not more than 1.2 mm-2.0 mm, for example, the outer diameter of the atomizing catheter is 1.8mm, and the atomizing catheter can reach the lung section which can not be reached by the endoscope to realize accurate atomizing administration.
Since the nebulizing catheter according to the present application can extend into the bronchi, its length can be adapted accordingly, for example, the length of the tube 100 is 800mm to 1200mm.
The proximal end of the tube 100 is generally connected to a fluid-conveying infusion or storage device, and for ease of assembly, a fitting 200, such as a conventional luer fitting or the like, may be pre-secured to the proximal end of the tube 100, either by threading or snap-fitting to facilitate quick connection to an external line.
The pipe joint 200 may adopt a single interface or a plurality of parallel interfaces according to different fluids, when a plurality of interfaces are provided, the pipe joint 200 may adopt a three-way mode, a four-way mode, or the like, and a control valve may be configured for at least one interface, or certainly, the control valve may also adopt an external or detachable mode, and is connected to the pipe joint 200 only when necessary.
Inside the body 100 are channels for transporting fluid, each channel extending from the proximal end of the body 100 to the distal end of the body 100 and meeting in communication with the atomizing head. I.e. independent in each passage before reaching the atomising head, and in particular for different phase fluids, to avoid impairing atomisation in the event of premature mixing.
In some embodiments, at least two of the channels may meet at the proximal end of the tube 100, merge into one channel, and extend distally.
The tube 100 has a length from the proximal end to the distal end, and each channel may extend along the length of the tube 100, i.e., in the same manner as the tube 100, in some embodiments, the channels may extend in an inclined manner, a spiral winding manner, etc., relative to the length of the tube 100, and in the case of multiple channels, the channels may extend in the same or different manners.
In some embodiments, the atomizing head 300 is configured with a micro-channel chip 320 therein, and the fluid is atomized through the micro-channel chip 320.
For example, the fluid is a liquid phase in which therapeutic substances can be dispersed, the micro-channel chip 320 has multiple layers of micro-channels therein, the particles after fluid atomization reach about 5 microns, and the fluid can have a high spray rate.
The pipe body 100 includes an inner pipe 120 and an outer pipe 110, the outer pipe 110 may be made of a metal pipe or a polymer material, and the inner pipe 120 is made of a metal material (for example, a stainless steel pipe), and is more pressure-resistant and also convenient to be drawn into a smaller pipe diameter.
Referring to fig. 5 and 6, in order to facilitate assembly and control the spraying state of the fluid at the atomizing port, the distal end of the tube 100 is an open structure and is covered with a housing 340, the housing 340 is provided with an atomizing port 341, the tube 100 and the housing 340 define a cavity, and the micro flow channel chip 320 is fixed in the cavity.
Referring to fig. 7 and 9, the number and location of spray outlets 341 may be arranged according to the desired treatment location, or spray orientation, for example, in one embodiment spray outlets 341 are located on the distal housing wall of housing 340.
In one embodiment, the spray outlet 341 is a single outlet opening in the center of the wall of the distal housing.
In one embodiment, the plurality of spray outlets 341 are located on the distal side wall of the housing 340.
In one embodiment, the plurality of spray outlets 341 are located on the peripheral wall of the housing 340.
In one embodiment, the spray outlets 341 are multiple, at least one on the distal housing wall of the housing 340 and at least one on the peripheral wall of the housing 340.
The micro flow channel chips 320 may be all located in the housing 340 in the axial direction of the tube 100, i.e., the axial position does not intersect with the tube 100, or all located in the tube 100, i.e., the axial position does not intersect with the housing 340.
It is also possible that the axial position of the micro flow channel chip 320 intersects both the housing 340 and the tube 100.
With reference to fig. 7 to 10, in order to facilitate the pre-assembly, in an embodiment, an atomization catheter is provided, which includes a tube 100, one end of the tube 100 is a proximal end, and the other end is a distal end that can extend into a bronchus, a channel that can transport fluid from the proximal end to the distal end is formed inside the tube 100, an atomization head 300 is disposed at the distal end of the tube 100, and the fluid in the channel is atomized by the atomization head 300 and then output;
the micro flow channel chip 320 is mounted in the housing 340 by a chip holder 330.
The proximal side of the microchannel chip 320 is an inlet 321, the distal side is an outlet 328, and the outlet 328 abuts against the distal housing wall of the housing 340 and is aligned with the spray outlet 341.
If the spray outlets 341 are also provided on the peripheral wall of the housing 340, the outlet 328 of the microchannel chip 320 is spaced from the wall of the distal end side of the housing 340 so as to avoid the spray outlets 341 on the peripheral wall.
The chip holder 330 may be fixed to the housing 340 by at least one of welding, bonding, and interference fit, or the chip holder 330 and the housing 340 may be fixed without direct fixing means, and the relative position of the chip holder 330 within the housing 340 is limited by the fit (abutting) between the adjacent components. It is preferable to avoid shaking or slipping of the chip holder 330 within the housing 340.
The chip holder 330 has a through region along the axial direction of the tube 100 for allowing the fluid to pass through and to escape the microchannel chip 320, and the microchannel chip 320 is mounted on the through region.
The micro flow channel chip 320 may be fixed in the chip holder 330 by means of adhesion, for example, UV glue.
In order to further reduce weight or improve compliance, the chip carrier 330 may also be provided with radial hollowed-out areas 331. At this time, the chip holder 330 forms a proximal socket 332 and a distal socket 333 on both sides of the hollow 331 in the axial direction, and the proximal end and the distal end of the microchannel chip 320 are respectively inserted into the corresponding sockets on the chip holder 330.
The micro flow channel chip 320 is fixedly connected in the chip holder 330 by gluing, and the hollow area 331 can be used as an operation area for dispensing.
The inlet 321 of the micro fluidic channel chip 320 can be directly connected to the fluid channel in the tube 100, or connected to the fluid channel through a connector.
In combination with the above embodiment, the inner tubes 120 for transporting fluid may be fixedly inserted directly into the inlets 321 of the microchannel chips 320, or may be butted against each other by a chip holder 330 connector.
In one embodiment, the chip carrier 330 connection is a connection sleeve 310.
The distal end of the fluid passage is butted against the proximal end of the connection sleeve 310, i.e., the inner tube 120 for transporting fluid is fixedly inserted to the proximal end of the connection sleeve 310.
In other embodiments, the section of the inner tube 120 has a flared structure, and the proximal portion of the connection sleeve 310 is fixedly inserted into the flared structure.
The distal end of the connecting sleeve 310 is butted against the inlet 321 of the microchannel chip 320, and the two can be butted by a plug fit or a direct butt joint.
When directly butted against each other, the chip carriers 330 may be utilized to limit each other.
In one embodiment, the distal end of the connection sleeve 310 is inserted into the proximal end of the chip holder 330 and butted against the micro flow channel chip 320 inside the chip holder 330.
For example, the distal end of the connection sleeve 310 and the proximal end of the microchannel chip 320 share the proximal socket 332 of the chip holder 330. That is, they are inserted from both axial sides of the proximal socket 332 and are in sealing engagement with the inner wall of the proximal socket 332 to prevent fluid leakage.
The connecting sleeve 310 is a multi-segment structure in the axial direction, and is respectively connected with the inner tube 120, the outer tube 110 and the chip holder 330 in a matching manner.
Different peripheral shapes and/or sizes are arranged among the multiple sections, namely a step structure can be formed between the adjacent sections, and the axial direction of the bearing is convenient to prop against and limit other adjacent parts.
For example, the chip holder 330 connector (i.e., the connecting sleeve 310) is an inner hollow structure, and the axial middle portion has a positioning shoulder for matching with the outer tube 110, which constitutes the main body section 311 in a multi-section structure.
The positioning shoulder has a substantially cylindrical shape, and the distal end of the outer tube 110 is fixedly secured to the outer periphery of the main body 311 by bonding (e.g., UV glue curing).
The outer shell 340 with the spray nozzle 341 and the outer tube 110 may be adhered by glue, for example, the distal end of the outer tube 110 is inserted into the outer shell 340, and the outer shell 340 and the outer tube 110 enclose and encapsulate the chip holder 330, the chip holder 330 connector, and the micro flow channel chip 320.
The body section 311 has a proximal end docking section 312 and a distal end docking section 313 at its two axial ends, wherein the distal end docking section 313 is inserted into the proximal socket 332 of the chip carrier 330, for positioning and limiting relative rotation, the cross section of the distal end docking section 313 is non-circular, such as polygonal, etc., and is rectangular in the figure, and matches with the shape of the proximal socket 332, and the distal end docking section 313 and the chip carrier 330 can be fixed by bonding or welding, such as laser welding.
A gap is formed between the distal end docking section 313 and the micro flow channel chip 320, and the gap forms a buffer region between the inner tube 120 and the micro flow channel chip 320, so that a certain state adjustment space is provided before the fluid enters the micro flow channel chip 320, and the fluid has a better dispersion effect after entering the micro flow channel chip 320.
The connection sleeve 310 may be an integral structure, and for convenience of processing, the connection sleeve 310 may also be formed by fixedly connecting after being processed separately, specifically, the proximal end butt-joint section 312, the distal end butt-joint section 313, and the main body section 311 of the connection sleeve 310 are processed separately and then fixedly connected in the axial direction as the connection 310.
The inner tube 120 is inserted and fixed to the proximal end docking section 312 of the chip holder 330 connector, and when the inner tube 120 is a stainless steel tube, it can be welded and fixed to the inner wall of the proximal end docking section 312 by soldering or the like.
Some of the following embodiments provide improvements to the micro flow channel chip 320.
Referring to fig. 10, in one embodiment, the micro fluidic channel chip 320 has an inlet 321 and an outlet 328 opposite each other, wherein the inlet 321 is in communication with the fluidic channel and the outlet 328 is in communication with the spray outlet 341.
The micro flow channel chip 320 may be composed of two glass sheets and a silicon wafer with an etched flow channel, wherein the two glass sheets are respectively bonded to two etched surfaces of the silicon wafer to form a liquid micro flow channel.
The microchannel chip 320 has an atomizing section H3 therein, and a plurality of distribution members 326 are arranged in the atomizing section H3.
The fluid further disperses in passing through the distribution member 326 until atomized.
The distribution members 326 are cylindrical or granular, etc., and may be distributed in an array or random manner, for example, the gaps between the distribution members 326 are determined according to the material to be sprayed, such as the viscosity of the fluid, the dispersion of the therapeutic material or the particle size, for example, the gaps between the distribution members 326 are generally 5 to 100 micrometers; the size of the distribution member 326 is 10-20 microns, and the height and diameter of the distribution member are 10-20 microns, for example, a cylinder.
In order to improve the atomization effect, in an embodiment, the microchannel chip 320 includes a flow splitting section H1, a pressure increasing section H2, and the atomization section H3, which are sequentially distributed from the inlet 321 to the outlet 328.
To optimize distribution, in one embodiment, the inlet 321 is divided into a plurality of zones, each of which leads in parallel into the plenum section H2. For example, the inlet 321 is divided into a plurality of regions by the first partition 322 in the flow dividing section H1. The first spacer 322 is not strictly limited in shape and functions primarily as a dividing region to direct the fluid into multiple streams into the plenum section H2.
In order to increase the fluid flow rate and improve the subsequent atomization effect in the pressurizing section H2, in an embodiment, one or a plurality of parallel pressurizing flow channels are arranged in the pressurizing section H2, and each pressurizing flow channel has a tendency of gradually narrowing.
With respect to the tendency of narrowing, for example, the apex angle of the tip end (i.e., the output side) of the pressurizing flow path is 3 to 15 degrees.
In one embodiment, each of the pressurizing channels may be defined by a plurality of guide pillars 329 arranged in sequence, and the narrowing tendency is understood as the sectional area gradually becomes smaller to increase the fluid pressure.
On the same side of a certain pressurized flow channel, a gap may be provided between two adjacent flow guide columns 329, but at least the general flow tendency of the fluid is ensured. In other embodiments, two sides of each pressurizing flow passage can also be closed structures.
When the two sides of each pressurizing flow passage adopt the closed structures, the pressurizing flow passages are at least opened at the tail ends to be communicated with the atomizing section H3, and in addition, the pressurizing flow passages can also be only opened at the two sides adjacent to the tail end parts, namely, the two sides far away from the tail end parts adopt the closed structures.
In order to better guide the fluid into each pressurizing channel, a second spacer 323 is provided at the input of two adjacent pressurizing channels.
The first spacer 322 divides the inlet 321 into N regions, and the second spacer 323 divides the pressurizing section H2 into M pressurizing flow channels, where M is greater than N, such as M = N + (2-8), and M =2N, for example. In the figure, M =4, n =8 is taken as an example.
In one embodiment, a third partition 325 is provided at the extreme end of each plenum flow passage to facilitate the discharge of fluid from both sides for further output to the atomizing zone H3.
Each spacer may be a block shape, wherein the first spacer 322 may have a size slightly larger than the second spacer 323. The second spacer 323 and the third spacer 325 are both similar in size.
In one embodiment, the distribution member 326 is also disposed near the end of each plenum flow passage.
As for the entire microchannel chip 320, the reasonable distribution of the segments can ensure the atomization effect, for example, the length ratio of the flow dividing segment H1, the pressure increasing segment H2, and the atomization segment H3 is 1: (2-10): (1-5).
In order to direct the direction of the atomized spray at the outlet 328 of the microchannel chip 320 and further enhance the atomization effect, in one embodiment, the interior of the microchannel chip 320 is gradually converged near the outlet 328. The liquid is more beneficial to the collection and mutual collision of the liquid, and the aerosol liquid drops with smaller diameter are formed.
In one embodiment, a flow guide 327 is disposed inside the micro flow channel chip 320 and adjacent to the outlet 328, wherein the flow guide 327 divides the area adjacent to the outlet 328 into two branches, and the two branches bypass the flow guide 327 and meet the outlet 328.
The flow guide member 327 may be a bar shape as a whole and extend in the flow guide direction, or the flow guide member 327 may be a column shape. The cross section of the cylindrical shape is seen to be circular, but the cross section can also be oval or drop-shaped.
The flow guide part 327 is in a cylindrical shape to avoid dead flowing angles, and preferably has a cambered surface structure at the periphery thereof to guide fluid and reduce resistance.
As shown in fig. 10, in operation, after the liquid chemical is injected from the proximal tube joint 200, the liquid chemical enters the micro flow channel chip 320 through the inner tube 120, and flows out of the micro flow channel chip 320 through the chip outlet 328.
In which the first spacer 322 at the inlet 321 first divides the fluid flow once, for example, as shown by the arrow X1 in fig. 10, the convex surface of the first spacer 322 is bonded to the glass sheet to support the glass sheet. A row of second spacers 323 is provided downstream of the first spacers 322 and slightly offset from the first spacers 322 to provide further flow splitting, for example, as indicated by arrow X2 in fig. 10, with the second spacers 323 contacting and supporting the glass sheets.
The row of guide columns 329 is arranged at the pressurizing section H2, the distance between every two adjacent rows of guide columns 329 is smaller and smaller, a pressurizing channel is formed, the fluid is pressurized, a row of third spacing members 325 are arranged at the tail end of the pressurizing channel, the convex surfaces of the third spacing members 325 can be bonded with the glass sheets, the glass sheets are further supported, and the glass sheets are prevented from being crushed due to uneven stress.
In the atomizing section H3, a plurality of small cylindrical distribution members 326 are uniformly disposed at the front end near the outlet 328, and the fluid (for example, liquid) randomly moves among the small cylindrical distribution members and collides with each other, thereby facilitating the formation of aerosol droplets with smaller diameter.
A cylinder or a flow guide element 327 is disposed at a central position near the outlet 328, the flow guide element 327 and two side walls inside the micro flow channel chip 320 form two narrower channels or two branches, the liquid is extruded through the narrow channels, the liquid is extruded along the tangential direction of the cylinder, for example, as shown by an arrow X3 in fig. 10, the liquid in the two channels collides to form more uniform and smaller aerosol droplets, and the aerosol droplets enter the human body.
All possible combinations of the technical features of the embodiments described above may not be described for the sake of brevity, but should be considered as being within the scope of the present disclosure as long as there is no contradiction between the combinations of the technical features. When technical features in different embodiments are represented in the same drawing, it can be seen that the drawing also discloses a combination of the embodiments concerned.
The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the claims. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, and these are all within the scope of protection of the present application.

Claims (10)

1. An atomization catheter convenient to assemble is characterized by comprising a catheter body, wherein one end of the catheter body is a near end, the other end of the catheter body is a far end capable of extending into a bronchus, a channel capable of conveying fluid from the near end to the far end is arranged inside the catheter body, an atomization head is arranged at the far end of the catheter body, and the fluid in the channel is atomized by the atomization head and then output;
a micro-channel chip is arranged in the atomizing head, and the fluid is atomized by the micro-channel chip;
the far end of the tube body is of an open structure and is covered with a shell, the shell is provided with a spray nozzle, the tube body and the shell enclose a cavity, and the micro-channel chip is fixed in the cavity.
2. The easy-to-assemble nebulizing catheter of claim 1 wherein the microchannel chip is mounted within the housing by a chip holder, the chip holder being secured to the housing by at least one of welding, adhesive bonding, and interference fit.
3. The easy-to-assemble atomization catheter of claim 2, wherein the chip holder has a through-hole along the axial direction of the tube body, and the microchannel chip is mounted in the through-hole.
4. The easy-to-assemble atomization catheter of claim 2, wherein the chip holder is provided with a radial hollow, the chip holder forms a proximal socket and a distal socket on both axial sides of the hollow, and the proximal end and the distal end of the microchannel chip are respectively inserted into the corresponding sockets on the chip holder.
5. The easy-to-assemble nebulizing catheter of claim 4 wherein the tube is docked with the microchannel chip by a adapter sleeve, the distal end of the adapter sleeve being inserted into the proximal end of the chip holder and docked against or with a gap opposite the microchannel chip inside the chip holder.
6. The easy-to-assemble nebulizing catheter of claim 5, wherein the tube body comprises an inner tube and an outer tube nested with each other, the inner tube has a lumen for conveying fluid, and the connection sleeve has a multi-segment structure in the axial direction and is respectively connected with the inner tube, the outer tube and the chip holder in a matching manner.
7. The easy-to-assemble atomization catheter as claimed in claim 6, wherein the connecting sleeve is of a hollow structure, the middle part of the connecting sleeve in the axial direction is provided with a positioning shoulder matched with the outer tube, the positioning shoulder forms a main body section in a multi-section structure, and the far end of the outer tube is fixedly sleeved on the periphery of the main body section.
8. The easy-to-assemble nebulizing catheter of claim 6 wherein the distal end of the outer tube is inserted into the housing, and the housing and the outer tube enclose the chip holder, the connection sleeve and the microchannel chip.
9. The easy-to-assemble atomization catheter of claim 7, wherein the main body section of the connecting sleeve is axially provided with a proximal butt section and a distal butt section at two ends, the distal butt section is inserted into the proximal socket of the chip holder, and the cross section of the distal butt section is matched with the shape of the proximal socket of the chip holder.
10. The easy-to-assemble atomization tube of claim 9, wherein the inner tube is fixedly inserted into the proximal butt section of the connection sleeve, and the inner tube is fixedly connected to an inner wall of the proximal butt section.
CN202123142046.1U 2021-05-26 2021-12-13 Atomizing pipe convenient to assembly Active CN218739765U (en)

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CN202122723587.7U Active CN216934312U (en) 2021-05-26 2021-11-08 Compact atomizing conduit
CN202111315644.6A Active CN114129837B (en) 2021-05-26 2021-11-08 Nebulizing catheter, nebulizing drug delivery system, control method, computer device and drug delivery device
CN202111314161.4A Active CN114129834B (en) 2021-05-26 2021-11-08 Atomization conduit for improving atomization effect
CN202122746668.9U Active CN217489461U (en) 2021-05-26 2021-11-08 Nebulizing catheter and administration device
CN202111315633.8A Active CN114129836B (en) 2021-05-26 2021-11-08 Compact atomizing catheter
CN202122723073.1U Active CN217162788U (en) 2021-05-26 2021-11-08 Atomizing catheter and administration equipment suitable for multiphase fluid
CN202122723590.9U Active CN216934313U (en) 2021-05-26 2021-11-08 Atomization catheter for improving atomization effect
CN202111314163.3A Active CN114129835B (en) 2021-05-26 2021-11-08 Nebulization catheter for multiphase fluids, nebulization dosing system, control method, computer device and dosing device
CN202123135902.0U Active CN217489463U (en) 2021-05-26 2021-12-13 Atomizing catheter for administration of medicine through bronchus
CN202123140053.8U Active CN217489464U (en) 2021-05-26 2021-12-13 Atomizing catheter capable of targeting drug delivery
CN202123140349.XU Active CN217489465U (en) 2021-05-26 2021-12-13 Atomization conduit for improving atomization dispersion effect
CN202123142046.1U Active CN218739765U (en) 2021-05-26 2021-12-13 Atomizing pipe convenient to assembly
CN202210590560.1A Active CN115177823B (en) 2021-05-26 2022-05-26 Atomizing catheter and atomizing drug delivery system using same
CN202210590557.XA Active CN115177822B (en) 2021-05-26 2022-05-26 Atomizing catheter

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CN202122723587.7U Active CN216934312U (en) 2021-05-26 2021-11-08 Compact atomizing conduit
CN202111315644.6A Active CN114129837B (en) 2021-05-26 2021-11-08 Nebulizing catheter, nebulizing drug delivery system, control method, computer device and drug delivery device
CN202111314161.4A Active CN114129834B (en) 2021-05-26 2021-11-08 Atomization conduit for improving atomization effect
CN202122746668.9U Active CN217489461U (en) 2021-05-26 2021-11-08 Nebulizing catheter and administration device
CN202111315633.8A Active CN114129836B (en) 2021-05-26 2021-11-08 Compact atomizing catheter
CN202122723073.1U Active CN217162788U (en) 2021-05-26 2021-11-08 Atomizing catheter and administration equipment suitable for multiphase fluid
CN202122723590.9U Active CN216934313U (en) 2021-05-26 2021-11-08 Atomization catheter for improving atomization effect
CN202111314163.3A Active CN114129835B (en) 2021-05-26 2021-11-08 Nebulization catheter for multiphase fluids, nebulization dosing system, control method, computer device and dosing device
CN202123135902.0U Active CN217489463U (en) 2021-05-26 2021-12-13 Atomizing catheter for administration of medicine through bronchus
CN202123140053.8U Active CN217489464U (en) 2021-05-26 2021-12-13 Atomizing catheter capable of targeting drug delivery
CN202123140349.XU Active CN217489465U (en) 2021-05-26 2021-12-13 Atomization conduit for improving atomization dispersion effect

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CN114129836A (en) 2022-03-04
CN217489464U (en) 2022-09-27
CN216934313U (en) 2022-07-12
CN115177823A (en) 2022-10-14
CN114129835B (en) 2024-05-28
CN114129837B (en) 2024-05-28
CN216934312U (en) 2022-07-12
CN114129837A (en) 2022-03-04
CN115177823B (en) 2024-05-28
CN217489463U (en) 2022-09-27
CN217489465U (en) 2022-09-27
CN217162788U (en) 2022-08-12
CN114129836B (en) 2024-05-28
CN114129834A (en) 2022-03-04
CN114129834B (en) 2024-05-28
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CN114129835A (en) 2022-03-04
CN115177822B (en) 2024-05-28

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