CN217854676U

CN217854676U - Supplementary liquid feeding device of chromatographic column

Info

Publication number: CN217854676U
Application number: CN202220511025.8U
Authority: CN
Inventors: 赵武新; 史佳豪
Original assignee: Zhejiang Boyi Biotechnology Co ltd
Current assignee: Zhejiang Boyi Biotechnology Co ltd
Priority date: 2022-03-10
Filing date: 2022-03-10
Publication date: 2022-11-22
Anticipated expiration: 2032-03-10

Abstract

The utility model provides a chromatographic column auxiliary liquid adding device, which relates to the field of separation and purification, and comprises a liquid adding device arranged on a chromatographic column funnel, wherein the liquid adding device comprises a fixed disc, a support bar, a connecting piece, a connecting pipe, a liquid storage ball, a liquid inlet, a liquid guide pipe and a liquid separation claw, the support bar is symmetrically arranged at the top of the fixed disc, the connecting piece is arranged above the fixed disc, one end of the support bar is fixedly connected with the connecting piece, the liquid storage ball is arranged above the connecting piece, and the liquid inlet is arranged above the liquid storage ball; the utility model discloses a first belt pulley of motor drive rotates, and the rethread belt drives the second belt pulley and rotates to drive the catheter and rotate, and then make and divide the liquid claw to rotate, spill the eluent on the inner wall of chromatography post through centrifugal force, and flow to the silica gel surface along the post wall, cause destruction to the silica gel surface when can preventing to add the eluent.

Description

Supplementary liquid feeding device of chromatographic column

Technical Field

The utility model relates to a separation and purification technical field especially relates to a supplementary liquid feeding device of chromatographic column.

Background

The chromatographic technique is also called column chromatographic technique, and its main principle is that according to the difference of distribution coefficients of all components in sample mixture in stationary phase and mobile phase, the components are separated by means of repeated distribution. It includes column chromatography, paper chromatography, thin layer chromatography, high performance liquid chromatography, etc. At present, column chromatography is an important commonly used technology essential for separating and purifying mixtures in natural product laboratories, chemical laboratories, biological laboratories and related industrial production, and mainly comprises normal-pressure column chromatography, reduced-pressure column chromatography and pressurized column chromatography. The normal-pressure column chromatography is the simplest column chromatography, and has the characteristics of convenience and simplicity in operation, easiness in obtaining experimental conditions, high separation efficiency and the like, so that the normal-pressure column chromatography is widely applied;

chinese patent No. CN201720528262.4 discloses a chromatography column capable of automatically feeding liquid, which comprises a chromatography column connected to a water-raising pump, wherein a grinding opening at the top end of the chromatography column is connected with a liquid storage ball, the upper end of the liquid storage ball is connected with an adapter with an upper adjusting valve, a rubber hose is connected to the adapter, the other end of the rubber hose is connected to the water-raising pump, and the water-raising pump is placed in a liquid storage tank; a dropping liquid port with a lower regulating valve is arranged below the chromatographic column. Use this device not need artifical frequent interpolation eluent to the chromatographic column, and can guarantee that eluent adds into the liquid storage ball accurately, can also realize the autosegregation purification through adjusting the governing valve, but when adding the expansion agent in toward the chromatographic column through the liquid storage ball, directly from the top drippage, can cause certain destruction to the silica gel surface in the chromatographic column, for example make silica gel surface part sunken etc. the expansion agent is not good along the silica gel surface diffusion time chromatography effect of this kind of unevenness, consequently the utility model provides a chromatographic column assists liquid feeding device in order to solve the problem that exists among the prior art.

SUMMERY OF THE UTILITY MODEL

To the above problem, the utility model provides a liquid feeding device is assisted to chromatographic column, this liquid feeding device is assisted to chromatographic column passes through the rotation of the first belt pulley of motor drive, and the rethread belt drives the rotation of second belt pulley to drive the catheter and rotate, and then make and divide the liquid claw to rotate, spill the eluent on the inner wall of chromatographic column through centrifugal force, and flow to the silica gel surface along the column wall, cause destruction to the silica gel surface when can preventing to add the eluent.

For realizing the purpose of the utility model, the utility model discloses a following technical scheme realizes: the utility model provides a supplementary liquid feeding device of chromatography column, is including setting up the liquid feeding device on chromatography column funnel, the liquid feeding device includes fixed disk, bracing piece, connecting pipe, liquid storage ball, inlet, catheter and minute liquid claw, the top symmetry of fixed disk is equipped with the bracing piece, the top of fixed disk is equipped with the connecting piece, the one end and the connecting piece fixed connection of bracing piece, the top of connecting piece is equipped with the liquid storage ball, the top of liquid storage ball is equipped with the inlet, the central point department of putting of fixed disk runs through to rotate and installs the catheter, the upper end and the connecting piece of catheter rotate to be connected, the lower extreme of liquid storage ball is equipped with the connecting pipe, connecting pipe lower extreme and connecting piece fixed connection and with catheter intercommunication, the lower extreme of catheter is equipped with minute liquid claw, one side at fixed disk top is equipped with and drives catheter pivoted drive assembly.

The further improvement is that: the drive assembly comprises an installation bin, a motor, a first belt pulley, a second belt pulley and a belt, the motor is arranged inside the installation bin, the output end of the motor is provided with the first belt pulley, the upper end of the catheter is provided with the second belt pulley, and the first belt pulley is linked with the second belt pulley through the belt.

The further improvement lies in that: the liquid inlet is provided with a sealing cover in a threaded manner, and the connecting pipe is provided with a valve.

The further improvement lies in that: the liquid storage ball is made of glass materials and is provided with scales.

The further improvement lies in that: divide the whole semicircle sphere that is of liquid claw, divide the outside of liquid claw lower extreme to be equipped with out the liquid hole, it is equipped with the multiunit to go out the liquid hole.

The further improvement lies in that: the support rod is right-angled, and a reinforcing column is arranged at the right angle of the support rod.

The further improvement is that: the separating claw is positioned in the funnel, and the distance between the separating claw and the funnel is 0.5-0.8cm.

The beneficial effects of the utility model are that: the utility model discloses a first belt pulley of motor drive rotates, and the rethread belt drives the second belt pulley and rotates, thereby it rotates to drive the catheter, and then makes and divide the liquid claw to rotate, spill the eluent on the inner wall of chromatography post through centrifugal force, and flow to the silica gel surface along the column wall, cause destruction to the silica gel surface when can preventing to add the eluent, can store the eluent temporarily through setting up of liquid storage ball simultaneously, and the setting of scale, be convenient for observe the quantity of eluent, the cooperation valve is convenient for close.

Drawings

Fig. 1 is a front view of the present invention.

Fig. 2 is a rear view of the present invention.

Fig. 3 is a bottom view of the separating claw of the present invention.

Fig. 4 is a cross-sectional view of the present invention.

Wherein: 1. a funnel; 2. fixing the disc; 3. a support bar; 4. a connecting member; 5. a connecting pipe; 6. liquid storage balls; 7. a liquid inlet; 8. a catheter; 9. a liquid separation claw; 10. installing a bin; 11. a motor; 12. a first pulley; 13. a second pulley; 14. a belt; 15. a sealing cover; 16. a valve; 17. calibration; 18. a liquid outlet hole; 19. and (4) reinforcing the column.

Detailed Description

In order to deepen the understanding of the present invention, the following embodiments will be combined to make the present invention do further details, and the present embodiment is only used for explaining the present invention, and does not constitute the limitation of the protection scope of the present invention.

According to the drawings of fig. 1, 2, 3 and 4, the embodiment provides a chromatographic column auxiliary liquid adding device, which comprises a liquid adding device arranged on a chromatographic column funnel 1, wherein the liquid adding device comprises a fixed disc 2, a support bar 3, a connecting piece 4, a connecting pipe 5, a liquid storage ball 6, a liquid inlet 7, a liquid guide pipe 8 and a liquid separating claw 9, the support bar 3 is symmetrically arranged at the top of the fixed disc 2, the connecting piece 4 is arranged above the fixed disc 2, one end of the support bar 3 is fixedly connected with the connecting piece 4, the liquid storage ball 6 is arranged above the connecting piece 4, the liquid inlet 7 is arranged above the liquid storage ball 6, the liquid guide pipe 8 is rotatably arranged at the central position of the fixed disc 2 in a penetrating manner, the upper end and the connecting piece 4 of catheter 8 rotate to be connected, the lower extreme of liquid storage ball 6 is equipped with connecting pipe 5, 5 lower extremes of connecting pipe and 4 fixed connection of connecting piece and communicate with catheter 8, the lower extreme of catheter 8 is equipped with divides liquid claw 9, one side at 2 tops of fixed disk is equipped with and drives 8 pivoted drive assembly of catheter, when using, increases the eluant to liquid storage ball 6 in through inlet 7, makes catheter 8 rotate through drive assembly to it is rotatory to drive divides liquid claw 9, through centrifugal force, the eluant is got rid of on the column wall of chromatography post or funnel 1's the inner wall, and flows to the silica gel surface along the inner wall, causes destruction to the silica gel surface when can preventing to add the eluant.

Drive assembly is including installation storehouse 10, motor 11, first belt pulley 12, second belt pulley 13 and belt 14, the inside of installation storehouse 10 is equipped with motor 11, the output of motor 11 is equipped with first belt pulley 12, the upper end of catheter 8 is equipped with second belt pulley 13, link through belt 14 between first belt pulley 12 and the second piece belt pulley, make first belt pulley 12 rotate through starting motor 11 to drive second belt pulley 13 through belt 14 and rotate, cooperation connecting piece 4, thereby make catheter 8 rotate.

The liquid inlet 7 is provided with a sealing cover 15 in a threaded manner, the connecting pipe 5 is provided with a valve 16, liquid in the liquid storage ball 6 can be protected through the sealing cover 15, and meanwhile, due to the arrangement of the valve 16, an operator can conveniently control the downward flow of the eluent.

The liquid storage ball 6 is made of glass, the scales 17 are arranged on the liquid storage ball 6, the using amount of the eluent can be observed in real time through the scales 17, so that the eluent can flow downwards conveniently for quantification, the amount of the eluent in the liquid storage ball 6 can be known, and liquid adding is convenient.

The whole body of the liquid separation claw 9 is in a semi-sphere shape, liquid outlet holes 18 are formed in the outer side of the lower end of the liquid separation claw 9, and multiple groups of the liquid outlet holes 18 are formed.

The bracing piece 3 is the right angle form, the right angle department of bracing piece 3 is equipped with strengthens post 19, supports stock solution ball 6 and connecting piece 4 through bracing piece 3, strengthens the setting of post 19, makes its supporting effect better.

The separating claw 9 is positioned in the funnel 1, and the distance between the separating claw 9 and the funnel 1 is 0.5-0.8cm.

This supplementary liquid feeding device motor 11 of chromatographic column drives first belt pulley 12 and rotates, rethread belt 14 drives second belt pulley 13 and rotates, thereby drive catheter 8 and rotate, and then make and divide liquid claw 9 to rotate, spill the eluent on the inner wall of chromatographic column wall or funnel 1 through centrifugal force, and flow to the silica gel surface along the column wall, cause destruction to the silica gel surface when can preventing to add the eluent, can store the eluent temporarily through setting up of liquid storage ball 6 simultaneously, and the setting of scale 17, be convenient for observe the quantity of eluent, cooperation valve 16 is convenient for close.

The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. The utility model provides a supplementary liquid feeding device of chromatographic column, is including setting up the liquid feeding device on chromatographic column funnel (1), its characterized in that: the liquid feeding device comprises a fixed disc (2), a supporting rod (3), a connecting piece (4), a connecting pipe (5), a liquid storage ball (6), a liquid inlet (7), a liquid guide pipe (8) and liquid separation claws (9), wherein the supporting rod (3) is symmetrically arranged at the top of the fixed disc (2), the connecting piece (4) is arranged above the fixed disc (2), one end of the supporting rod (3) is fixedly connected with the connecting piece (4), the liquid storage ball (6) is arranged above the connecting piece (4), the liquid inlet (7) is arranged above the liquid storage ball (6), the liquid guide pipe (8) is arranged in a central position of the fixed disc (2) in a penetrating and rotating mode, the upper end of the liquid guide pipe (8) is rotatably connected with the connecting piece (4), the connecting pipe (5) is arranged at the lower end of the liquid storage ball (6), the connecting pipe (5) is fixedly connected with the connecting piece (4) and communicated with the liquid guide pipe (8), the liquid guide pipe (8) is arranged at the lower end of the liquid guide pipe (8), the liquid separation claws (9) is arranged at the one side of the top of the fixed disc (2) and is provided with a driving assembly for driving the liquid guide pipe (8) to rotate.

2. The chromatographic column auxiliary liquid adding device of claim 1, which is characterized in that: the drive assembly comprises an installation bin (10), a motor (11), a first belt pulley (12), a second belt pulley (13) and a belt (14), the motor (11) is arranged inside the installation bin (10), the first belt pulley (12) is arranged at the output end of the motor (11), the second belt pulley (13) is arranged at the upper end of the liquid guide pipe (8), and the first belt pulley (12) is linked with the second belt pulley through the belt (14).

3. The auxiliary liquid adding device for chromatographic column according to claim 1, characterized in that: a sealing cover (15) is installed on the liquid inlet (7) in a threaded mode, and a valve (16) is arranged on the connecting pipe (5).

4. The auxiliary liquid adding device for chromatographic columns according to claim 3, characterized in that: the liquid storage ball (6) is made of glass, and scales (17) are arranged on the liquid storage ball (6).

5. The chromatographic column auxiliary liquid adding device of claim 1, which is characterized in that: divide liquid claw (9) whole to be the semicircle sphere form, divide the outside of liquid claw (9) lower extreme to be equipped with out liquid hole (18), it is equipped with the multiunit to go out liquid hole (18).

6. The chromatographic column auxiliary liquid adding device of claim 1, which is characterized in that: the supporting rod (3) is right-angled, and a reinforcing column (19) is arranged at the right angle of the supporting rod (3).

7. The auxiliary liquid adding device for chromatographic columns according to claim 5, characterized in that: the separating claw (9) is positioned in the funnel (1), and the distance between the separating claw (9) and the funnel (1) is 0.5-0.8cm.