CN217503347U

CN217503347U - Conveying device

Info

Publication number: CN217503347U
Application number: CN202123439906.8U
Authority: CN
Inventors: 徐宏; 许金苗; 项腾; 肖创业; 吴越; 胡艳艳
Original assignee: Hangzhou Kunbo Biotechnology Co Ltd
Current assignee: Hangzhou Kunbo Biotechnology Co Ltd
Priority date: 2021-06-30
Filing date: 2021-12-29
Publication date: 2022-09-27
Anticipated expiration: 2031-12-29
Also published as: CN114699160A; CN114526441B; CN114376711A; CN217960278U; CN218420016U; CN114526441A; CN114521953A; CN114636102B; CN218075189U; CN114526444B; CN114504372B; CN218494750U; CN114719183A; CN114711944A; CN114504372A; CN114636102A; CN114526444A

Abstract

The application provides a conveying device, which is used for conveying working media to a cryoablation device from a first pressure container and comprises a first passage and a gas-liquid separation device, wherein a first pipeline is provided with a first end and a second end which are opposite, the first pipeline comprises an outer pipe and an isolation sleeve positioned in the outer pipe, the isolation sleeve divides the first pipeline into an inner layer structure and an outer layer structure in the radial direction, the first end of the inner layer is communicated with the first pressure container, the second end of the inner layer is communicated with the cryoablation device, the second end of the outer layer serves as an inflow side and is communicated with the second end of the inner layer, and the first end of the outer layer serves as a precooling outflow side; the gas-liquid separation device is of a cylindrical structure and is arranged in the isolation sleeve, the first end of the cylindrical structure is open, the second end of the cylindrical structure is closed, the inside of the cylindrical structure is a first channel, a second channel is arranged between the outer wall of the cylindrical structure and the inner wall of the isolation sleeve, and a through hole for communicating the first channel and the second channel is formed in the side wall of the cylindrical structure. Precooling and gas-liquid separation can reduce the gas blockage probability.

Description

Conveying device

Technical Field

The application relates to the technical field of medical instruments, in particular to a conveying device.

Background

In the course of combating cancer, chemotherapy, radiotherapy and surgical treatment have become three common approaches to the treatment of malignant tumors, and tumor immunotherapy is also under intense research. Minimally invasive treatment of tumors is an important supplement to surgical treatment, wherein physical ablation is increasingly applied to various treatment means of tumors, including microwave, freezing, laser, radio frequency, high-power focused ultrasound and the like, so as to necrose cancer tissues.

In the early 20 th century, the rapid development of industry and science and technology, and the refrigeration substances such as concentrated oxygen, liquid oxygen, concentrated nitrogen, liquid nitrogen, dry ice and the like are successfully prepared in the progress of the industrial science and technology, so that the step of commercial development is accelerated, a new place of medical refrigeration is opened up, and the application of the low-temperature technology in medical treatment is promoted. Various refrigeration technologies have been developed in response to the continuous progress of low-temperature science, and gas throttling technologies, phase-change cooling, vapor pressure absorption refrigeration, thermoelectric refrigeration and the like are main refrigeration schemes used in modern medicine.

In addition, some cryosurgical treatment systems use liquid nitrogen as a freezing working medium, the phase-change cooling efficiency of the liquid cryogen is higher than that of throttling refrigeration, but the liquid nitrogen undergoes phase change under the condition of poor heat insulation of a transmission pipeline, so that 'air blockage' is caused, further transmission of the liquid nitrogen is influenced, heat transfer deterioration is caused, and finally cryoablation failure is caused.

SUMMERY OF THE UTILITY MODEL

The application discloses conveyor can reduce the emergence of stifled phenomenon of gas.

The application discloses a conveyor for by first pressure vessel to cryoablation equipment transport working medium, conveyor includes:

the first pipeline is provided with a first end and a second end which are opposite, the first pipeline comprises an outer pipe and an isolation sleeve in the outer pipe, the isolation sleeve divides the first pipeline into an inner layer structure and an outer layer structure in the radial direction, the first end of the inner layer is communicated with a first pressure container, the second end of the inner layer is communicated with a cryoablation device, the second end of the outer layer serves as an inflow side and is communicated with the second end of the inner layer, and the first end of the outer layer serves as a precooling outflow side;

the gas-liquid separation device is of a cylindrical structure and is arranged in the isolation sleeve, the first end of the cylindrical structure is open, the second end of the cylindrical structure is closed, a first channel is arranged inside the cylindrical structure, a second channel is arranged between the outer wall of the cylindrical structure and the inner wall of the isolation sleeve, and through holes communicated with the first channel and the second channel are formed in the side wall of the cylindrical structure.

Several alternatives are provided below, but not as an additional limitation to the above general solution, but merely as a further addition or preference, each alternative being combinable individually for the above general solution or among several alternatives without technical or logical contradictions.

Optionally, a diversion trench for forming the second channel is formed in the outer wall of the tubular structure, and the through hole is formed in a trench wall of the diversion trench.

Optionally, the outer wall of the cylindrical structure abuts against the inner wall of the spacer sleeve.

Optionally, the diversion trench is spirally wound on the outer wall of the cylindrical structure.

Optionally, the through holes are arranged along the diversion trench in a plurality.

Optionally, the first end of the isolation sleeve extends out of the first end of the outer tube, the extended part is used as a bottom insertion tube, and the length of the extended part can at least extend to a position below the liquid level in the first pressure vessel.

Optionally, an output valve is configured on the first pipeline, and the output valve has an output channel communicated with the inner layer and a feedback channel communicated with the outer layer.

Optionally, the outer layer is communicated with a safety relief valve, and the precooling outflow side is connected with a control valve.

Optionally, a temperature sensor for detecting the temperature of the inner layer and a pressure sensor for detecting the pressure of the outer layer are arranged on the first pipeline.

The application provides a conveyor, at the transport low temperature working medium in-process, the mass flow gas content in the gas-liquid two-phase working medium that gets into first passageway is higher than the mass flow liquid content, reduces the mass flow gas content of the freezing working medium that gets into cryoablation equipment via the second passageway, and then reduces the stifled phenomenon of gas.

Drawings

FIG. 1 is a schematic illustration of a low pressure fluid system of the present application;

FIG. 2 is a schematic view of a liquid cryogen tube-in-tube configuration;

FIG. 3 is a schematic view of a liquid refrigerant tube gas-liquid separation device;

FIG. 4 is a schematic diagram of a liquid cryogen delivery valve;

FIG. 5 is a schematic diagram of a liquid cryogen vessel configuration;

fig. 6 is a schematic structural diagram of a phase change pressure vessel.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

It will be understood that when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. When a component is referred to as being "disposed on" another component, it can be directly on the other component or intervening components may also be present.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description of the present application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

In the field of cryoablation, phase-change freezing of liquid freezing media has a higher freezing efficiency than throttling freezing of gaseous freezing media. The commonly used liquid freezing working medium is liquid nitrogen, but the liquid nitrogen is easy to generate phase change in a conveying pipeline to generate 'air blockage', so that the pressure in the pipeline is overhigh, the output quantity of the liquid nitrogen is influenced, the system freezing and melting range is unstable, and the consistent melting effect is difficult to form.

The current liquid nitrogen working medium freezing and ablating system solves the problem of air blockage by using supercritical pressure transmission, but the working pressure of the freezing and ablating system is overhigh, so that the potential safety hazard exists, the requirement on materials of equipment such as a liquid nitrogen transmission pipeline is higher, and the cost is high.

With reference to fig. 1 to 6, the present application provides a delivery device for delivering a working medium from a first pressure vessel (i.e., a liquid working medium pressure vessel C1) to a cryoablation apparatus (CP), wherein the working medium is at a low temperature and in a gas-liquid two-phase state during delivery, and the first pressure vessel is used for storing the liquid working medium and is capable of delivering the working medium through a power apparatus or its own pressure.

The conveying device comprises a first pipeline (a liquid refrigerant output pipeline L1) and a gas-liquid separation device, wherein the first pipeline is provided with a first end and a second end which are opposite, the first pipeline comprises an outer pipe (L1-1-4) and a separation sleeve (L1-1-5) arranged in the outer pipe, the outer pipe and the separation sleeve form a liquid refrigerant pipe (L1-1), the separation sleeve divides the first pipeline into an inner layer structure and an outer layer structure in the radial direction, the first end of an inner layer (namely an inflow channel L1-1-3) is communicated with a first pressure container (C1), the second end of the inner layer (L1-1-3) is communicated with the cryoablation device, the second end of an outer layer (namely a return channel L1-1-2) serves as an inflow side and is communicated with the second end of the inner layer, and the first end of the outer layer (L1-1-2) serves as a precooling outflow side.

The conveying device precools before cryoablation work, and in the precooling process, the flow paths of working media are two paths: the first path is via the inner layer to the cryoablation device (CP); the second path is from the inflow side of the inner layer and the outer layer to the precooling outflow side of the outer layer. Wherein two ways all cool off the inlayer in the output process, and first way can also cool off the cryoablation equipment, and the second way can also cool off the skin and form the isolation layer and block the inlayer and carry out the heat exchange with the air outside the first pipeline, and this process is continuously gone on in order to reduce the difference in temperature of inlayer and working medium for when the follow-up cryoablation that carries on, it leads to a large amount of gasification in first pipeline to reduce the working medium because of the heat exchange, reduces the gas and blocks up.

The gas-liquid separation device is of a cylindrical structure and is arranged in the isolation sleeve, the first end of the cylindrical structure is open, the second end of the cylindrical structure is closed, a first channel (namely a gas-liquid separation device base pipe L1-1-4-2) is arranged inside the cylindrical structure, a second channel is arranged between the outer wall of the cylindrical structure and the inner wall of the isolation sleeve, and a through hole (namely an exhaust hole L1-1-4-3) for communicating the first channel and the second channel is formed in the side wall of the cylindrical structure. Because of the arrangement of the through holes, part of the working medium can enter the first channel, and the gas content of the mass flow of the part of the two-phase flow is higher than the liquid content of the mass flow; and the gas-liquid two-phase flow which flows through the second channel and does not enter a base pipe (L1-1-4-2) of the liquid refrigerant pipe gas-liquid separation device has a mass flow liquid content higher than a mass flow gas content. Further reducing the gasification amount of the working medium in the second channel and reducing the air blocking probability during precooling or ablation. Because the second end of the gas-liquid separation device is closed, the working medium entering the first channel flows to the first end, and the flow direction of the working medium entering the first channel is opposite to that of the working medium entering the second channel. And (3) further analyzing by combining the flow path of the working medium in the first path, wherein the flow path of the working medium is also divided into two paths: the third path is from the second channel to the cryoablation device or the outer layer; the fourth path is from the second channel, the through hole, the first channel to the first end of the first channel.

The working medium stored in the first pressure container in the embodiment is liquid nitrogen, so that the proportion of liquid nitrogen gasification influenced by temperature is reduced, the phenomenon of air blockage is avoided, the output liquid nitrogen dosage is stable and controllable, and the stable cryoablation effect is realized.

The method for reducing air blockage can be to reduce the temperature difference between the inner layer temperature and the working medium during cryoablation, for example, in another embodiment, the liquid refrigerant pipe (L1-1) is a sleeve structure, and at least comprises two or more sleeve structures; comprising: the system comprises a liquid refrigerant pipe heat insulation channel, a liquid refrigerant pipe return channel (L1-1-2), a liquid refrigerant pipe inflow channel (L1-1-3) and a liquid refrigerant pipe gas-liquid separation device (L1-1-4). The liquid refrigerant pipe (L1-1) is sequentially provided with a heat insulation channel (L1-1-1), a backflow channel (L1-1-2) and a flow inlet channel (L1-1-3) from outside to inside through the three channels, the heat insulation channel can be communicated with the backflow channel (L1-1-2) and flow through the same working medium, or can be not communicated with the backflow channel (L1-1-2) and the flow inlet channel (L1-1-3) and flow through other low-temperature working mediums, so that heat exchange is further blocked. In other embodiments, heat exchange is blocked by providing an insulating layer on the outer layer.

The guide groove used for forming the second channel is formed in the outer wall of the tubular structure, the guide groove is communicated with the first end and the second end, so that the working medium can flow on the guide groove, and the through holes are formed in the groove wall of the guide groove for effective gas-liquid separation. The outer wall of the cylindrical mechanism is attached to the inner wall of the isolation sleeve, the guide groove is of a groove structure, working media can only flow through the guide groove, and then the working media can certainly pass through the through hole, so that the gas-liquid separation efficiency is improved. Under the cross section, the second channel is enclosed by the cell wall of guiding gutter and the inner wall of isolation sleeve, and wherein the cell wall of guiding gutter is the arc, and the cell wall is smooth, reduces the heat that produces because of the friction with the working medium, reduces because of friction factor gasification probability takes place. The through hole is provided with an arc-shaped bottom, and is circular in shape and convenient to process.

In order to further improve the separation efficiency, the method adopted is that the diversion trench is spirally wound on the outer wall of the cylindrical structure to form a spiral channel, so that the flowing path of the working medium is prolonged. Or a plurality of through holes are distributed along the diversion trench. Wherein the guiding gutter has arranged 1 ~ 8 through-holes in spirally wound every round, and these through-holes equidistant distribution in tubular structure's circumference.

In one embodiment, the first end of the isolation sleeve extends out of the first end of the outer tube, the extending part is used as a bottom inserting tube, and the length of the extending part at least can extend to be below the liquid level in the first pressure container, so that liquid-phase working medium can be continuously output after precooling and ablation. And the first end of the outer pipe is positioned outside the first pressure container, so that the working medium is output from the first end of the inner layer and then returns to the first end of the outer layer through the second end to flow out, and most or all of the inner layer is cooled.

The first end of the cylindrical structure and the first end of the spacer sleeve are axially adjacent to each other. The mutual proximity is understood that the first end of the gas-liquid separation device is also positioned below the liquid level in the first pressure container, so that the working medium directly enters the second channel for gas-liquid separation during output, and the working medium entering the first channel can return to the first pressure container and be liquefied, thereby realizing local circulation and saving resources.

Referring to FIG. 4, in one embodiment, the first conduit is configured with an outlet valve (i.e., liquid cryogen outlet valve L1-2) having an outlet passage (L1-2-1) in communication with the inner layer and a return passage (L1-2-2) in communication with the outer layer. The liquid cryogen output valve (L1-2) comprises two pairs of input-output channels, a first input-output channel (corresponding to the output channel) and a second input-output channel (corresponding to the return channel); the first input-output passage communicates with a liquid refrigerant pipe inflow passage (L1-1-3); the second input-output passage communicates with a liquid refrigerant pipe return passage (L1-1-2); when the liquid refrigerant outlet valve (L1-2) is in an open state, fluid in the liquid refrigerant pipe inflow passage (L1-1-3) of the liquid refrigerant pipe (L1-1) dynamically flows into and out of the first input-output passage. In a precooling procedure of the cryoablation process, a precooling fluid recovery solenoid valve (L2-2) is in an open state, and backflow fluid in a liquid refrigerant pipe backflow channel (L1-1-2) dynamically flows into and out of a second input-output channel.

Wherein, the precooling outflow side is connected with a control valve (namely a precooling fluid recovery electromagnetic valve L2-2). After the precooling program of the cryoablation process is finished, the precooled fluid recovery solenoid valve (L2-2) is in a closed state, the backflow fluid in the liquid refrigerant pipe backflow channel (L1-1-2) stops flowing, and the fluid in the second input-output channel stops flowing. The liquid cryogen output valve (L1-2) comprises two pairs of input-output channels, the first input-output channel being for supply of liquid cryogen; the second inlet-outlet passage is used for pre-cooling the valve body of the liquid cryogen outlet valve (L1-2).

And the precooling outflow side is connected with the outer side to a second pressure container for recovery, in the precooling process, a precooling fluid recovery electromagnetic valve (L2-2) is in an open state, and fluid working media enter a precooling fluid recovery pipeline (L2) through a liquid refrigerant pipe backflow channel (L1-1-2).

In one embodiment, the outer layer is communicated with a safety relief valve (L1-3). The liquid refrigerant pipe backflow channel (L1-1-2) is characterized in that backflow fluid in the liquid refrigerant pipe backflow channel (L1-1-2) dynamically flows in a precooling program in a cryoablation process, and the backflow fluid in the liquid refrigerant pipe backflow channel (L1-1-2) stops flowing after the precooling program in the cryoablation process is finished; after the return fluid in the liquid cryogen tube return passage (L1-1-2) ceases to flow, the fluid pressure within the layer should be limited to within the operating pressure range; the safety pressure relief valve (L1-3) prevents the pressure in the liquid refrigerant pipe backflow channel (L1-1-2) from being too high, and when the pressure is higher than the threshold pressure of the liquid refrigerant pipe backflow channel, the safety pressure relief valve (L1-3) is opened and releases the pressure; when the pressure is lower than the threshold pressure of the liquid refrigerant pipe return channel, the safety relief valve (L1-3) is closed.

In one embodiment, a temperature sensor (L1-5) for detecting the temperature of the inner layer and a pressure sensor (L1-6) for detecting the pressure of the outer layer are arranged on the first pipeline. The temperature sensor is capable of detecting a temperature of the inner layer at the second end, indicating that pre-cooling is complete when a preset temperature is reached.

The conveying device can pre-cool before cryoablation, reduces the gas blockage phenomenon caused by temperature difference change during ablation, and is provided with the gas-liquid separation device in the inner layer, so that exhaust is realized in the pre-cooling and ablation processes, and the gas blockage phenomenon is further reduced.

Referring to fig. 1, an embodiment of the present application discloses a low pressure fluid system for enhancing interventional cryoablation performance, comprising at least one of: the system comprises a liquid working medium pressure container (C1), a gaseous working medium pressure container (C2), a phase change pressure container (C3), a liquid refrigerant output pipeline (L1), a precooling fluid recovery pipeline (L2), a cryoablation working pressure reducing pipeline (L3), a cryoablation working pressure boosting pipeline (L4), a gaseous working medium output pipeline (L5), a replacement and rewarming pipeline (L6), an air return recovery pipeline (L7), a system flow monitoring and recovery condition control pipeline (L8), a vacuum degree creating pipeline (L9) and cryoablation equipment (CP) as interventional ablation equipment.

The above modules, containers, conduits and related apparatus and methods may be applied to low pressure cryoablation, for example, less than 3MPa (e.g., about 0.5MPa operating pressure), each of which may independently implement certain unit operations and in some cases may be integrated with each other into a relatively complete low pressure fluid system, and are described below with respect to the components, but not strictly limited to the configuration at the same time:

1) the pressure vessel for accommodating liquid-phase working medium and gas-phase working medium: a liquid working medium pressure vessel (a first pressure vessel C1), a gaseous working medium pressure vessel (a second pressure vessel C2), and a phase change pressure vessel (a third pressure vessel C3).

A first pressure container (C1), wherein a liquid-phase working medium is stored in the first pressure container C1, is connected with a cryoablation device CP through a first pipeline L1 and is conveyed;

the first pressure vessel C1 is connected to the second pressure vessel C2 via a fourth line L4; a third pressure container C3 is arranged in the first pressure container C1 and can change the phase of the liquid-phase working medium into a gas-phase working medium.

The first pressure container C1 is provided with a third pipeline L3 for exhausting and decompressing;

a liquid working medium pressure vessel (C1), preferably a dewar pressure vessel, for storing liquid working medium of the freezing process in the cryoablation procedure; the method comprises the following steps: a liquid working medium pressure sensor (C1-1) and a liquid working medium liquid level sensor (C1-2).

A gaseous working medium pressure container (namely a second pressure container C2), wherein a gaseous working medium is stored in the second pressure container (C2), and is connected with the first pressure container (C1) through a fourth pipeline L4 and conveys the gaseous working medium to the first pressure container (C1);

the second pressure vessel (C2) is connected with the third pressure vessel (C3) through a fifth pipeline (L5) and receives gas-phase working medium from the third pressure vessel (C3);

the second pressure container (C2) is connected with the cryoablation device (CP) through a sixth pipeline (L6) and conveys the heated gaseous working medium;

the second pressure vessel (C2) is connected to the gaseous working medium of the cryoablation device (CP) and/or of the first line (L1) via an eighth line (L8).

The Dewar pressure container is preferably used for storing gaseous working media which are replaced before being used, rewarming process and recycled by the air return channel in the cryoablation procedure; the method comprises the following steps: a gaseous working medium pressure sensor (C2-1) and a gaseous working medium pressure relief valve (C2-2).

③ the phase-change pressure vessel (i.e. the third pressure vessel C3) is connected and transported to the second pressure vessel (C2) through a fifth pipeline (L5).

The device is used for changing the phase of a liquid working medium into a gas working medium, and the gas after phase change is conveyed to a gas working medium pressure container (C2) through a gas working medium output pipeline (L5) through a pressure control element (L5-5). The method comprises the following steps: the device comprises a liquid working medium one-way circulation device (C3-1), a phase change heating device (C3-2), a container heat insulation layer (C3-3), a liquid level sensor (C3-4) and a temperature sensor (C3-5).

2) Nine functional pipelines comprising valves, sensing and control elements: the system comprises a liquid refrigerant output pipeline (a first pipeline L1), a precooling fluid recovery pipeline (a second pipeline L2), a cryoablation working pressure reducing pipeline (a third pipeline L3), a cryoablation working pressure boosting pipeline (a fourth pipeline L4), a gaseous working medium output pipeline (a fifth pipeline L5), a replacement and rewarming pipeline (a sixth pipeline L6), an air return recovery pipeline (a seventh pipeline L7), a system flow monitoring and recovery condition control pipeline (an eighth pipeline L8), and a vacuum degree creating pipeline (a ninth pipeline L9).

The delivery device of the above embodiment, in which the liquid refrigerant output pipeline (the first pipeline L1) is used for delivering liquid working medium, includes:

a liquid cryogen tube (L1-1); a liquid cryogen outlet valve (L1-2); a safety relief valve (L1-3); the liquid refrigerant output pipeline pressure transmitter (L1-4) and the temperature sensor (L1-5) participate in closed-loop control, and are used for monitoring the state parameters of the fluid working medium entering the flexible cryoprobe; the liquid cryogen is delivered out a check valve (L1-6) to avoid back flow.

Secondly, gas working media flow through the precooling fluid recovery pipeline (namely the second pipeline (L2)), one end of the second pipeline (L2) is connected with the first pipeline (L1), and the other end of the second pipeline is connected with the eighth pipeline (L8) and finally conveyed into the second pressure container (C2).

A second conduit (L2) for conveying fluid working medium to a system flow monitoring and recovery condition control conduit (L8) during a pre-cooling process of a cryoablation procedure, comprising:

a pre-cooling fluid recovery pipe (L2-1); a precooling fluid recovery electromagnetic valve (L2-2), wherein a heat exchanger in a cryoablation procedure is opened and is closed after reaching a precooling temperature threshold range; a pre-cooled fluid recovery check valve (L2-3) to avoid backflow.

(iii) a cryoablation working pressure relief conduit (i.e. a third conduit (L3) connected to the first pressure vessel (C1) for releasing pressure from the liquid working medium dewar pressure vessel (C1).

A cryoablation working pressure reducing tube (L3-1); and the cryoablation working pressure decompression electromagnetic valve (L3-2) is opened when the pressure of the liquid working medium in the liquid nitrogen working medium pressure container (C1) is higher than a release pressure threshold value, and is closed when the pressure of the liquid working medium is lower than the release pressure threshold value.

A cryoablation working pressure pressurization pipeline (i.e. a fourth pipeline (L4) which connects the first pressure vessel (C1) and the second pressure vessel (C2) and is used for inputting the gaseous working medium in the gaseous working medium pressure vessel (C2) into the liquid working medium dewar pressure vessel (C1) for pressurization, comprising:

a cryoablation working pressure booster pipe (L4-1); and the cryoablation working pressure boosting electromagnetic valve (L4-2) is opened when the pressure of the liquid working medium in the liquid nitrogen working medium pressure container (C1) is lower than a boosting pressure threshold value, and is closed when the pressure of the liquid working medium is higher than the boosting pressure threshold value. A cryoablation working pressure control element (L4-3) participates in closed loop control for adjusting the cryoablation working pressure.

A gaseous working medium output pipeline (namely, a fifth pipeline (L5) connects the third pressure vessel (C3) and the second pressure vessel (C2) and is used for inputting the gaseous working medium in the phase-change pressure vessel (C3) into the gaseous working medium pressure vessel (C2) for pressurization, and the method comprises the following steps:

a gaseous working medium output pipe (L5-1), a pressure monitoring element of a phase change pressure container (C3): a phase change pressure transmitter (L5-2); the phase change container pressure relief electromagnetic valve (L5-3) is opened and is used for emptying gas-phase working media in the phase change pressure container (C3) or creating a pressure difference between the liquid working medium pressure container (C1) and the phase change pressure container (C3) so that the liquid working media enter the phase change pressure container (C3) from the liquid working medium pressure container (C1) and is closed after the liquid working media enter; when the pressure threshold of the phase change pressure transmitter (L5-2) is higher than the gaseous working medium output pressure threshold, the gaseous working medium output electromagnetic valve (L5-4) is opened, otherwise, the gaseous working medium output electromagnetic valve is closed; the gaseous working medium output pressure control element (L5-5) is used for adjusting the pressure in the gaseous working medium pressure vessel (C2).

The displacement and rewarming pipeline (namely, the sixth pipeline (L6) connects the second pressure container (C2) with the cryoablation apparatus (CP) and is used for selectively heating the gaseous working medium in the gaseous working medium pressure container (C2) and then conveying the gaseous working medium to the cryoablation apparatus (CP) in the process of the cryoablation, and the method comprises the following steps:

a replacement and rewarming tube (L6-1); a replacement and rewarming solenoid valve (L6-2) that opens when in a replacement procedure in a cryoablation procedure and closes after the replacement procedure for replacing air within the cryoablation apparatus; when the gas working medium is in a rewarming process in a cryoablation program, the replacement and rewarming heat exchanger (L6-3) is started and used for heating the gas working medium in the replacement and rewarming pipe (L6-1) to reach a threshold temperature, and the rewarming temperature sensor (L6-4) participates in the rewarming process and is matched with and adjusts the heating power of the replacement and rewarming heat exchanger (L6-2) so that the gas working medium in the replacement and rewarming pipe (L6-1) reaches the threshold temperature; a replacement and rewarming one-way valve (L6-5) to avoid reverse flow.

Seventhly, one end of a return gas recovery pipeline (i.e. a seventh pipeline (L7)) is connected to the cryoablation apparatus (CP), and the other end of the return gas recovery pipeline is connected to an eighth pipeline (L8), so that return gas generated in the freezing process in the cryoablation procedure is delivered to a system flow monitoring and recovery condition control pipeline (L8), and the return gas recovery pipeline comprises:

a return air recovery pipe (L7-1); the return gas recovery pipeline is provided with a one-way valve (L7-2) to avoid reverse flow.

One end of an eighth pipeline (L8) is connected with a seventh pipeline (L7) and a second pipeline (L2) at the same time, the other end of the eighth pipeline is connected with a second pressure container (C2) and used for heating fluid working medium flowing from a pre-cooling fluid recovery pipeline (L2) in a pre-cooling process in a freezing and melting procedure and pumping the fluid working medium to a gaseous working medium pressure container (C2), and in the freezing and melting procedure, the fluid working medium flowing from a return gas recovery pipeline (L7) is heated in the freezing process and then is pumped to the gaseous working medium pressure container (C2) after the flow is measured by a flow meter, and the measured flow participates in the pressure control of the system, comprises the following steps:

a system flow monitoring and recovery condition control pipe (L8-1); a system flow monitoring and recovery condition control heat exchanger (L8-2) for heating fluid flowing from a pre-cooled fluid recovery line (L2) to a threshold temperature during a pre-cooling procedure of a cryoablation procedure; and freezing the fluid flowing from the return air recovery line (L7) during the cryoablation procedure to a threshold temperature; the system flow monitoring and recovery condition control temperature sensor (L8-3) participates in closed-loop control and is used for matching with the adjustment of the heating power of the system flow monitoring and recovery condition control heat exchanger (L8-2) to enable the fluid in the system flow monitoring and recovery condition control pipe (L8-1) to reach the threshold temperature; if the fluid working medium cannot reach the threshold temperature after being heated, the gas working medium recovery release valve (L8-7) is opened, and the fluid working medium is discharged to the atmosphere; the system flow monitoring and recovery condition control flowmeter (L8-4) is mainly used for monitoring the freezing process in a cryoablation program, and the fluid flow entering the system flow monitoring and recovery condition control pipe (L8-1) from the return air recovery pipe (L7-1) participates in closed-loop control, is used for prejudging the cryoablation effect, and is matched with pressure regulation to enable the cryoablation effect to meet the expectation. The system flow monitoring and recovery condition control extraction booster pump (L8-5), and the adjustment of the pumping power is matched with the adjustment of the working pressure, so as to further promote the smooth air return and enable the cryoablation effect to reach the expectation. System flow monitoring and recovery conditions control a check valve (L8-6) to prevent backflow.

Ninthly, a vacuum degree creation pipeline (i.e., a ninth pipeline L9) connects the cryoablation apparatus (CP) and the vacuum apparatus (L9-3) for creating a high vacuum degree for the cryoablation apparatus (CP) to achieve a good vacuum insulation effect includes:

a vacuum degree creation pipe (L9-1); the vacuum gauge (L9-2) is used for monitoring whether the vacuum degree reaches a threshold value requirement; the vacuum level creating pump set is used for creating high vacuum level, and the flexible cryoprobe has good vacuum insulation effect.

3) A cryoablation apparatus (CP) comprising a thermometric sensor and a heating element.

A cryoablation apparatus (CP) for performing a cryoablation procedure on a lesion after entering a human body through a natural orifice, comprising:

structures for enhancing interventional cryoablation performance; a distal thermocouple (CP1) of the cryoablation device for monitoring the temperature within the cryoprobe and participating in closed loop control; the distal end of the cryoablation device is a nickel-chromium wire used for the rewarming process in the cryoablation procedure. The cryoablation device may be a flexible cryoprobe or the like.

The working process of the low-pressure fluid system is described in the following with reference to the flow chart

The steps in the flowcharts are shown in order as indicated by the arrows, but the steps are not necessarily performed in order as indicated by the arrows. The steps are not performed in the exact order shown and described, and may be performed in other orders, unless explicitly stated otherwise. Moreover, at least some of the steps in the figures may include multiple sub-steps or multiple stages that are not necessarily performed at the same time, but may be performed at different times, and the order of performing the sub-steps or stages is not necessarily sequential, but may be performed alternately or alternately with other steps or at least some of the sub-steps or stages of other steps.

1) Starting a system, initializing, and reading a control threshold parameter stored in a memory; and simultaneously acquiring data of system sensors.

2) Firstly, the liquid level in a liquid working medium Dewar pressure container (C1) is judged, LLC1-2_ Lower Limit is a low liquid level early warning threshold value of the container, and a judgment program is executed:

if the current liquid level LLC1-2_ CL of the liquid working medium level sensor (C1-2) is less than LLC1-2_ Lower Limit, the system determines that the liquid level cannot maintain the cryoablation program, namely the LLC1-2_ Lower Limit is the volume of liquid nitrogen required by the redundancy-containing primary cryoablation program. Then, executing a liquid nitrogen supplementing program when LLC1-2_ CL is more than or equal to LLC1-2_ Upper Limit; and (5) ending liquid nitrogen canning.

If the current liquid level LLC1-2_ CL of the liquid working medium liquid level sensor (C1-2) is more than or equal to LLC1-2_ Lower Limit, the system considers that the cryoablation program can be executed.

3) The pressure in a liquid working medium Dewar pressure container (C1) is judged, and PC1_ IWP is a pressure threshold value when the pressure container is initialized; executing a judging program:

if the current pressure PC1-1_ CP of the liquid working medium pressure sensor (C1-1) is not more than PC1_ IWP, the system considers that the pressure in the pressure container meets the pressure requirement during initialization, and can continue to execute subsequent programs; PC1_ IWP is the initialization pressure of the liquid working medium dewar pressure vessel (C1) prior to use in a cryoablation procedure, which is typically the pressure at ordinary rest when the liquid working medium dewar pressure vessel (C1) is not in use. Note: the initial pressure PC1_ IWP of the pressure vessel is less than the working pressure PC1_ WP of the liquid working medium Dewar pressure vessel.

If the current pressure PC1-1_ CP of the liquid working medium pressure sensor (C1-1) is larger than PC1_ IWP, a pressure relief program is executed, and a pressure reduction electromagnetic valve (L3-2) for the cryoablation working pressure is opened for pressure relief until PC1-1_ CP is not more than PC1_ IWP.

4) Judging the pressure in a gaseous working medium pressure container (C2), wherein PC2_ IWP is a pressure threshold value when the pressure container is initialized; executing a judgment program:

if the current pressure PC2-1_ CP of the gaseous working medium pressure sensor (C2-1) is not more than PC2_ IWP, the system considers that the pressure in the pressure container meets the pressure requirement during initialization, and can continue to execute the subsequent procedures; PC2_ IWP is the initialization pressure of the gaseous working medium pressure container (C2) before the use of the cryoablation program, and the pressure is usually the gaseous working medium stored in the gaseous working medium pressure container (C2) after the last cryoablation program; because the gas in the gaseous working medium pressure container (C2) is the gas for recovering the precooling process and the cryoablation process, the gas is output in the rewarming process, and in order to ensure the normal recovery of the next operation in the precooling and cryoablation processes, the PC2_ IWP of the pressure is less than the working pressure PC2_ WP of the gaseous working medium pressure container (C2).

And if the current pressure PC2-1_ CP of the gaseous working medium pressure sensor (C2-1) is larger than PC2_ IWP, executing a pressure relief program, and opening the gaseous working medium pressure relief valve (C2-2) for pressure relief until the pressure PC2-1_ CP is less than or equal to PC2_ IWP.

5) Judging the pressure in the phase-change pressure container (C3), wherein the PC3_ IWP is the pressure threshold value of the pressure container during initialization; executing a judgment program:

if the current pressure PL5-2_ CP of the phase change pressure transmitter (L5-2) is not more than PC3_ IWP; the system considers the pressure within the pressure vessel to meet the pressure requirements at initialization and may proceed with the subsequent procedure. This pressure PC3_ IWP < the working pressure PC3_ WP inside the phase change pressure vessel (C3).

And if the current pressure PL5-2_ CP of the phase change pressure transmitter (L5-2) is larger than PC3_ IWP, executing a pressure relief program, and opening a phase change container pressure relief electromagnetic valve (L5-3) for pressure relief until PL5-2_ CP is less than or equal to PC3_ IWP.

6) Judging the current pressure PL5-2_ CP of the phase change pressure transmitter (L5-2) is greater than the current pressure PC2-1_ CP of the gaseous working medium pressure sensor (C2-1) of PC2-1_ CP, opening a gaseous working medium output electromagnetic valve (L5-4), and setting the output pressure of a gaseous working medium output pressure control element (L5-5): PL5-5_ SP _ OUT > PC2-1_ CP; at the moment, the gaseous working medium in the phase change pressure container (C3) enters the gaseous working medium pressure container (C2); until PL5-2_ CP-PC2-1_ CP <. DELTA.P 0, namely the pressure in the current phase change pressure vessel (C3) is equal to the pressure in the gaseous working medium pressure vessel (C2), closing the gaseous working medium output electromagnetic valve (L5-4); and the output of the gaseous working medium output pressure control element (L5-5) is cut off. The gaseous working medium of the phase-change pressure container (C3) is utilized, and the utilization rate is improved.

7-1) opening a liquid refrigerant output valve (L1-2), firstly entering a precooling program of a cryoablation process, and enabling all elements in a precooling fluid recovery pipeline (L2) and a system flow monitoring and recovery condition control pipeline (L8) to enter working states. And opening a precooling fluid recovery solenoid valve (L2-2), and controlling the start of a heat exchanger (L8-2) by system flow monitoring and recovery conditions.

The system flow monitoring and recovery condition control flow meter (L8-4) and the system flow monitoring and recovery condition control extraction booster pump (L8-5) have restrictions on fluid temperature, so the system sets a temperature threshold: TL8-2_ ET _ Lower Limit: system flow monitoring and recovery conditions control the first heat exchange temperature of the heat exchanger and TL8-2_ ET _ Upper Limit: the system flow monitoring and recovery condition controls a second heat exchange temperature of the heat exchanger; corresponding to the lower limit of the temperature range and the upper limit of the temperature range, respectively.

If: the current fluid temperature collected by a system flow monitoring and recovery condition control temperature sensor (L8-3):

TL8-3_ CT is more than or equal to TL8-2_ ET _ Lower Limit & & TL8-3_ CT is less than or equal to TL8-2_ ET _ Upper Limit; and a gas working medium recovery release valve (L8-7) is closed, and fluid enters a gas working medium pressure container (C2) for pressurization through a system flow monitoring and recovery condition control flowmeter (L8-4) and a system flow monitoring and recovery condition control extraction booster pump (L8-5).

If: TL8-3_ CT < TL8-2_ ET _ Lower Limit | | | TL8-3_ CT > TL8-2_ ET _ Upper Limit; and opening a gas working medium recovery release valve (L8-7). And calling a fuzzy self-tuning PID temperature control algorithm, closing a gas working medium recovery release valve (L8-7) after the temperature meets the condition that TL8-3_ CT is more than or equal to TL8-2_ ET _ Lower Limit and TL8-3_ CT is less than or equal to TL8-2_ ET _ Upper Limit, and enabling the fluid to enter a gas working medium pressure container (C2) for pressurization through a system flow monitoring and recovery condition control flowmeter (L8-4) and a system flow monitoring and recovery condition control extraction booster pump (L8-5).

The cycle of the above steps is pressurized to event: the current pressure TL1-5_ CT-TL1-5_ PT precooling threshold temperature < [ delta ] T0| (or) the current pressure of the gaseous working medium pressure vessel (C2) second pressurization closing pressure PC2_ PB _ CV-PC2-1_ CP gaseous working medium pressure sensor (C2-1) < [ delta ] P0, which is acquired by the liquid refrigerant output pipeline temperature sensor (L1-5).

If TL1-5_ CT-TL1-5_ PT < [ delta ] T0 occurs in the OR logic, the precooling process is finished, the liquid refrigerant output valve (L1-2) is closed, a system time delay device is started, the time delay interval Delta T is delayed, after the liquid refrigerant output valve (L1-2) is closed, residual fluid in the liquid refrigerant output pipeline (L1) and the precooling fluid recovery pipeline (L2) enters a gaseous working medium pressure container (C2); the system flow monitoring and recovery condition control draw booster pump is then turned off (L8-5).

If TL1-5_ CT-TL1-5_ PT <. DELTA.T 0 is NO, then event PC2_ PB _ CV-PC2-1_ CP <. DELTA.P 0 must have occurred; the pressure in the gaseous working medium pressure container (C2) meets the pressurization requirement; therefore shut down system flow monitoring and recovery condition control draw booster pump (L8-5); opening a gas working medium recovery release valve (L8-7) to discharge the fluid in the pipeline into the atmosphere until an event TL1-5_ CT-TL1-5_ PT <. DELTA.T 0 occurs, and achieving a precooling condition;

then closing the liquid refrigerant output valve (L1-2), starting a system time delay device, delaying the time interval delta t, and enabling residual fluid in the liquid refrigerant output pipeline (L1) and the precooling fluid recovery pipeline (L2) to enter a gaseous working medium pressure container (C2) after the liquid refrigerant output valve (L1-2) is closed; the system flow monitoring and recovery condition control draw booster pump (L8-5) was then shut down.

Next, judging the pressure condition of the gas working medium entering the gas working medium pressure container (C2), and opening a gas working medium pressure relief valve (C2-2) for pressure relief when the current pressure of a second pressure reduction opening threshold PC2_ RP _ OV-PC2-1_ CP gas working medium pressure sensor (C2-1) is less than delta P0; and closing the gaseous working medium pressure relief valve (C2-2) until the second pressure reduction closing threshold value <. DELTA.P 0 of the current pressure PC2-1_ CP-PC2_ RP _ CV of the gaseous working medium pressure sensor (C2-1).

7-2) judging that the current pressure PL5-2_ CP of the phase change pressure transmitter (L5-2) is more than or equal to the current pressure PC1-1_ CP of the PC1-1_ CP liquid working medium pressure sensor (C1-1); starting a phase change container pressure relief solenoid valve (L5-3), and closing a threshold LLC3-4_ CV-LLC 3-4_ CL when the current pressure PL5-2_ CP-atm of a phase change pressure transmitter (L5-2) is less than delta P0& a liquid level sensor (C3-4) is the first liquid level, and the current liquid level value of a liquid level sensor (C3-4) of a phase change pressure container (C3) is less than delta L0; and closing the pressure relief electromagnetic valve (L5-3) of the phase change container, and starting the phase change heating device (C3-2) for heating.

If the current pressure PL5-2_ CP < PC1-1_ CP & & phase change pressure container (C3) liquid level sensor (C3-4) of the phase change pressure transmitter (L5-2) is judged, the current liquid level value LLC3-4_ CL < LLC3-4_ Lower Limit liquid level sensor (C3-4) is judged to be a first low liquid level threshold value; starting a phase change container pressure relief solenoid valve (L5-3), and closing a threshold LLC3-4_ CV-LLC 3-4_ CL when the current pressure PL5-2_ CP-atm of a phase change pressure transmitter (L5-2) is less than delta P0& a liquid level sensor (C3-4) is the first liquid level, and the current liquid level value of a liquid level sensor (C3-4) of a phase change pressure container (C3) is less than delta L0; and closing the pressure relief electromagnetic valve (L5-3) of the phase change container, and starting the phase change heating device (C3-2) for heating.

7-2-2) if the current pressure PL5-2_ CP < PC1-1_ CP & & phase change pressure vessel (C3) liquid level sensor (C3-4) of the phase change pressure transmitter (L5-2) is judged, the current liquid level value LLC3-4_ CL is more than or equal to the first low liquid level threshold of the LLC3-4_ Lower Limit liquid level sensor (C3-4), and the phase change heating device (C3-2) starts heating.

After the phase change heating device (C3-2) is started, if the current pressure PL5-2_ CP of the phase change pressure transmitter (L5-2) is larger than the third Lower pressure increase threshold of PC3_ PB _ Lower Limit; and the current temperature TC3-5_ CT < TC3-5_ Upper Limit collected by the temperature sensor (C3-5): a temperature sensor (C3-5) a first high temperature threshold; the phase change heating device (C3-2) continues heating.

Until: the current pressure of the collected current temperature TC3-5_ CT is more than or equal to a first high-temperature threshold or a third pressurization closing threshold PC3_ PB _ CV-PL5-2_ CP variable pressure transmitter (L5-2) of a TC3-5_ Upper Limit temperature sensor (C3-5) and is less than delta P0; the variable heating device (C3-2) stops heating.

If the current pressure PL5-2_ CP of the phase change pressure transmitter (L5-2) is not more than the third Lower pressure increasing threshold of PC3_ PB _ Lower Limit and the current temperature TC3-5_ CT collected by the temperature sensor (C3-5) is not less than the first high temperature threshold of the TC3-5_ Upper Limit temperature sensor (C3-5), stopping heating, and if the current pressure is invalid, re-executing the pressure increasing process. Otherwise, the heating is continued until the above certain judgment condition appears.

When the device meets the requirement, and the current temperature TC3-5_ CT acquired by the temperature sensor (C3-5) is more than or equal to the current pressure of the TC3-5_ Upper Limit temperature sensor (C3-5) and less than delta P0 of the first high temperature threshold or the third pressurization closing threshold PC3_ PB _ CV-PL5-2_ CP variable pressure transmitter (L5-2), an output program is executed. And (3) opening the gaseous working medium output electromagnetic valve (L5-4), and setting the output pressure of the gaseous working medium output pressure control element (L5-5): PL5-5_ SP _ OUT > PC2-1_ CP; at the moment, the gaseous working medium in the phase change pressure container (C3) enters the gaseous working medium pressure container (C2); until the current pressure PL5-2_ CP-PC3_ PB _ OV third pressurization opening threshold of the variable pressure transmitter (L5-2) is <. DELTA.P 0| (or) the current pressure PL5-2_ CP-PC2-1_ CP gaseous working medium pressure sensor (C2-1) of the variable pressure transmitter (L5-2) is less than DELTA.P 0< here limit is determined by a controller, after the gaseous working medium pressure container (C2) is gradually pressurized, the PC2-1_ CP is gradually increased, but the requirement of the pressure controller is that the upstream pressure should be greater than the downstream pressure, so the controller should have the logic > | (or) the gaseous working medium pressure container (C2) and close the second pressurization closing pressure PC2_ PB _ CV-PC2-1_ CP, the gaseous working medium pressure sensor (C2-1) to close the gaseous working medium output electromagnetic valve (L5-4-CP) when the current pressure is less than DELTA.P 0, and the gaseous working medium output pressure control element (L5-5) is switched off.

The boosting process described above may be cycled through multiple cycles until the event: the current pressure < [ delta ] P0 of the second pressurization closing pressure PC2_ PB _ CV-PC2-1_ CP gaseous working medium pressure sensor (C2-1) of the gaseous working medium pressure container (C2) represents that the initialization pressurization process of the gaseous working medium pressure container (C2) is finished.

In order to prevent the pressure in the phase change pressure vessel C3 from being high at the time of stopping, a pressure relief judgment is introduced: and (3) opening a phase change container pressure relief solenoid valve (L5-3) when a third decompression opening threshold value is less than delta P0 of the current pressure PL5-2_ CP-PC3_ RP _ OV phase change pressure container (C3) of the phase change pressure transmitter (L5-2), and closing the phase change container pressure relief solenoid valve (L5-3) when a third decompression closing threshold value is less than delta P0 of the phase change pressure container (C3) of the current pressure PL5-2_ CP-PC3_ RP _ CV of the phase change pressure transmitter (L5-2). To prevent excessive pressure in C3.

8) After the process, the gaseous working medium pressure container (C2) meets the working pressure requirement: PC2_ WP; the phase change pressure vessel (C3) also meets its operating pressure requirements; PC3_ WP; the liquid cryogen output line (L1) has achieved adequate pre-cooling.

Therefore, the method has the following requirements of the cryoablation procedure, and the method comprises the steps of detecting or accessing system consumables until the system accesses the consumables, then accessing the system into a liquid working medium Dewar pressure container (C1) to build pressure and replace gas in the consumables.

9) Opening a replacement and rewarming electromagnetic valve (L6-2) and entering a replacement program; the purpose of replacement is to replace air and moisture in the inner pipeline of the consumable into gas working medium in a gas working medium pressure container (C2) before the freezing process. Starting a replacement and rewarming heat exchanger (L6-3), and heating the temperature of the replacement gas to room temperature after fuzzy self-setting PID temperature control algorithm, namely meeting the condition that TL6-4_ CT-room temperature is less than delta T0; the gas enters a system flow monitoring and recovery condition control pipeline (L8) after passing through a return gas recovery pipeline (L7). Then, a recovery flow similar to the precooling process is used for entering a gaseous working medium pressure container (C2), and the following steps are carried out:

the system flow monitoring and recovery condition control flow meter (L8-4) and the system flow monitoring and recovery condition control extraction booster pump (L8-5) have restrictions on fluid temperature, so the system sets a temperature threshold: TL8-2_ ET _ Lower Limit: system flow monitoring and recovery Condition controls the first Heat exchange temperature of the Heat exchanger and TL8-2_ ET _ Upper Limit: the system flow monitoring and recovery condition controls a second heat exchange temperature of the heat exchanger; corresponding to the lower limit of the temperature range and the upper limit of the temperature range, respectively.

If: TL8-3_ CT < TL8-2_ ET _ Lower Limit | | | TL8-3_ CT > TL8-2_ ET _ Upper Limit; the gas working medium recovery release valve (L8-7) is opened. And calling a fuzzy self-tuning PID temperature control algorithm, closing a gas working medium recovery release valve (L8-7) after the temperature meets the condition that TL8-3_ CT is more than or equal to TL8-2_ ET _ Lower Limit and TL8-3_ CT is less than or equal to TL8-2_ ET _ Upper Limit, and enabling the fluid to enter a gas working medium pressure container (C2) for pressurization through a system flow monitoring and recovery condition control flowmeter (L8-4) and a system flow monitoring and recovery condition control extraction booster pump (L8-5).

The displacement process is output from the gaseous working medium pressure container (C2) and then flows back to the gaseous working medium pressure container (C2); the process does not cause drastic changes in pressure, so pressure determination is not made in the process. In addition, the whole replacement process is maintained for a time Δ t 1.

The permutation process is ended and Probe _ ZH _ Flag is transmitted.

10) Raising the liquid working medium Dewar pressure container (C1) to working pressure; opening a cryoablation working pressure pressurization solenoid valve (L4-2); setting an output pressure PL4-3_ SP _ OUT > PC1_ PB _ CV first boost initialization closing threshold of a cryoablation working pressure control element (L4-3); so that the gaseous working medium pressure container (C2) pressurizes the liquid working medium Dewar pressure container (C1) through the cryoablation working pressure pressurizing pipeline (L4) until: first pressure boost initialization closing threshold PC1_ PB _ CV-PC1-1_ CP liquid working medium pressure sensor (C1-1)

Current pressure collected < [ delta ] P0; and (3) after the liquid working medium Dewar pressure container (C1) is pressurized, closing the cryoablation working pressure pressurizing electromagnetic valve (L4-2) and turning off the cryoablation working pressure control element (L4-3).

And after pressure build-up before ablation of the liquid working medium Dewar pressure container (C1) is finished, sending PC1_ PreCyro _ Flag.

11-1) when an event: probe _ ZH _ Flag occurs 1& & PC1_ precero _ Flag ═ 1, and cryoablation is ready. Waiting for an event: probe _ Cyro _ Star is 1; setting the cryoablation delay time: Δ t 2; opening a liquid cryogen output valve (L1-2); starting a cryoablation timer 2; when the cryoablation time length is delta t2, the freezing process of the Cycle is finished, and the cryocycle times Cryo _ Cycle + + in the cryoablation process; the liquid cryogen output valve (L1-2) is then closed. The freezing process of this cryoablation cycle is ended.

11-2) starting a rewarming process of the cryoablation cycle, starting a replacement and rewarming heat exchanger (L6-3), and meeting the temperature of rewarming gas after a fuzzy self-tuning PID temperature control algorithm: TL6-4_ CT < TL6-3_ RW _ Upper Limit & & TL6-3_ RW _ Lower Limit < TL6-4_ CT. Then, a temperature recovery timer3 is started, and when the temperature recovery time in the cryoablation is delta t3, the Cycle number Cryo _ Cycle + + is reset in the cryoablation process; then closing the electromagnetic valve L6-2; the replacement and rewarming heat exchanger (L6-3) was shut off.

After one freezing and rewarming cycle, judging an event:

Cryo_Cycle＝＝Cryo_Set&&ReWarm_Cycle＝＝RW_Set

when it occurs, it indicates the end of the cryocycle, otherwise, it continues to perform the cryoablation procedure.

11-3) in the above process, a recovery process is carried out, and the gas enters a system flow monitoring and recovery condition control pipeline (L8) after passing through a return gas recovery pipeline (L7).

Then, a recovery flow similar to the precooling process is used for entering a gaseous working medium pressure container (C2), and the following steps are carried out:

the system flow monitoring and recovery condition controlling flow meter (L8-4) and the system flow monitoring and recovery condition controlling extraction booster pump (L8-5) have limits on the fluid temperature, so the system sets a temperature threshold: TL8-2_ ET _ Lower Limit: system flow monitoring and recovery conditions control the first heat exchange temperature of the heat exchanger and TL8-2_ ET _ Upper Limit: the system flow monitoring and recovery condition controls a second heat exchange temperature of the heat exchanger; are respectively provided with

The lower limit of the temperature range corresponds to the upper limit of the temperature range.

If: the current fluid temperature collected by a system flow monitoring and recovery condition control temperature sensor (L8-3): TL8-3_ CT is more than or equal to TL8-2_ ET _ Lower Limit & & TL8-3_ CT is less than or equal to TL8-2_ ET _ Upper Limit; and a gas working medium recovery release valve (L8-7) is closed, and fluid enters a gas working medium pressure container (C2) for pressurization through a system flow monitoring and recovery condition control flowmeter (L8-4) and a system flow monitoring and recovery condition control extraction booster pump (L8-5).

If: TL8-3_ CT < TL8-2_ ET _ Lower Limit | | | TL8-3_ CT > TL8-2_ ET _ Upper Limit; and opening a gas working medium recovery release valve (L8-7).

And calling a fuzzy self-tuning PID temperature control algorithm, closing a gas working medium recovery release valve (L8-7) after the temperature meets the condition that TL8-3_ CT is more than or equal to TL8-2_ ET _ Lower Limit and TL8-3_ CT is less than or equal to TL8-2_ ET _ Upper Limit, and enabling the fluid to enter a gas working medium pressure container (C2) for pressurization through a system flow monitoring and recovery condition control flowmeter (L8-4) and a system flow monitoring and recovery condition control extraction booster pump (L8-5). When the event occurs: when PC2_ PB _ CV-PC2-1_ CP is less than delta P0, the recovered fluid does not enter the gaseous working medium pressure vessel (C2) and is discharged to the atmosphere from a bypass; when the event is:

Cryo_Cycle＝＝Cryo_Set&&ReWarm_Cycle＝＝RW_Set

when it occurs, it indicates the end of the freezing cycle, otherwise it continues to execute.

When the cryoablation starts, the vacuum equipment (L9-3) starts to work, and the vacuum degree is set to be vacuum; until the cryoablation procedure is completed.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features. When technical features in different embodiments are represented in the same drawing, it can be seen that the drawing also discloses a combination of the embodiments concerned.

The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the claims. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. A delivery device for delivering a working medium from a first pressure vessel to a cryoablation apparatus, the delivery device comprising:

the gas-liquid separation device is of a cylindrical structure and is arranged in the isolation sleeve, the first end of the cylindrical structure is open, the second end of the cylindrical structure is closed, a first channel is arranged inside the cylindrical structure, a second channel is arranged between the outer wall of the cylindrical structure and the inner wall of the isolation sleeve, and through holes for communicating the first channel and the second channel are formed in the side wall of the cylindrical structure.

2. The conveying device as claimed in claim 1, wherein the outer wall of the cylindrical structure is provided with a guiding groove for forming the second passage, and the through hole is formed in a groove wall of the guiding groove.

3. The delivery device of claim 2, wherein an outer wall of the cylindrical structure abuts an inner wall of the spacer sleeve.

4. The transfer device of claim 2 wherein the channels are helically wound around the outer wall of the tubular structure.

5. The conveying device according to any one of claims 2 to 4, wherein the through holes are arranged in plurality along the guide groove.

6. The transfer device of claim 1, wherein the first end of the isolation sleeve extends beyond the first end of the outer tube to serve as a footer tube and is at least as long as it extends below the liquid level within the first pressure vessel.

7. The delivery device of claim 1, wherein the first conduit is configured with an outlet valve having an outlet passage in communication with the inner layer and a return passage in communication with the outer layer.

8. The conveying device according to claim 1, wherein the outer layer is communicated with a safety relief valve, and a control valve is connected to the precooling outflow side.

9. The conveying apparatus as claimed in claim 1, wherein a temperature sensor for detecting a temperature of the inner layer and a pressure sensor for detecting a pressure of the outer layer are provided on the first pipe.