CN117338398B - Cryoablation needle with efficient heat recovery and thermal therapy functions - Google Patents

Cryoablation needle with efficient heat recovery and thermal therapy functions Download PDF

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Publication number
CN117338398B
CN117338398B CN202311534148.9A CN202311534148A CN117338398B CN 117338398 B CN117338398 B CN 117338398B CN 202311534148 A CN202311534148 A CN 202311534148A CN 117338398 B CN117338398 B CN 117338398B
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needle
ablation
welding spot
rewarming
input
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CN117338398A (en
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张海勇
罗大伟
王金龙
隆龙
宋波
郭其勇
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Canyon Medical Inc
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Canyon Medical Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00023Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00041Heating, e.g. defrosting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0231Characteristics of handpieces or probes
    • A61B2018/0262Characteristics of handpieces or probes using a circulating cryogenic fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0293Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument interstitially inserted into the body, e.g. needle

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
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Abstract

The invention belongs to the technical field of medical appliances, and in particular relates to a cryoablation needle with high-efficiency heat recovery and thermal therapy functions, which comprises an ablation needle head, wherein a needle rod is fixed at one end of the ablation needle head, medium conveying pipes are arranged in the ablation needle head and the needle rod, and the cryoablation needle also comprises: the rewarming unit is assembled in the ablation needle head; and the temperature measuring unit is assembled in the ablation needle head. According to the invention, the rewarming thermotherapy can be realized without an electric heating wire, compared with a gas throttling rewarming mode, the rewarming efficiency and the upper limit of the rewarming temperature are improved, compared with the electric heating wire rewarming mode, the rewarming efficiency is improved, the thermotarming effect is improved, and meanwhile, the risk of excessive ablation of extra normal tissues caused by different rewarming principles in the use of microwave or radio frequency rewarming modes is avoided.

Description

Cryoablation needle with efficient heat recovery and thermal therapy functions
Technical Field
The invention belongs to the technical field of medical appliances, and particularly relates to a cryoablation needle with high-efficiency heat recovery and thermal therapy functions.
Background
With the continuous development of medical imaging technologies such as nuclear magnetic resonance imaging and ultrasonic imaging. Early tumor minimally invasive surgical techniques such as cryoablation, microwave ablation, radio frequency ablation and the like have been developed. The cryoablation is to accurately insert a cryoablation needle into focus tissues in a body by means of medical imaging, and rapidly cooling, freezing and rewarming are realized in focus areas by the ablation needle, so that the focus tissues generate a series of irreversible injuries, and the aim of eliminating focuses is fulfilled. The cryoablation can generate a low-temperature ice ball in the cooling section, so that the pain degree in the operation of a patient is reduced while the focus tissue is inactivated, and the focus tissue can be inactivated again by utilizing high-speed temperature change in the rewarming process, so that the coagulation around the focus is realized, and the complications are reduced. Cryoablation not only reduces patient pain, but also reduces the risk of postoperative recurrence.
In the prior art, two types of rewarming modes of cryoablation are mainly adopted, namely, the gas throttling effect is utilized, but the requirement on pipeline pressure resistance is higher, the highest rewarming temperature is limited (the upper limit temperature of the rewarming is 40 ℃), and the cost of a gas phase working medium for rewarming is high; the other is to heat by using an electric heating wire, high-purity gas (commonly used nitrogen) with lower pressure is introduced in the heating process, and then the temperature is transferred to a focus tissue to realize the rewarming through heat conduction, so that the cost is lower, but the rewarming by using the electric heating wire still has the following problems:
1. the ablation needle with smaller diameter has smaller diameter of the heating wire, lower heating efficiency and slower rewarming speed, and the heating wire is difficult to fix;
2. spiral coils in the inside heating wire of ablation needle, though can improve the efficiency of rewarming, spiral helicine heating wire can increase the diameter of ablation needle by a wide margin, still can increase the air resistance, simultaneously, causes the vortex to the freezing medium of flowing, and spiral heating wire is difficult to fix more.
Aiming at the situation, the invention provides a cryoablation needle with high-efficiency heat recovery and thermal therapy functions, and the heat recovery process is replaced by an electrothermal therapy mode so as to solve the problems.
Disclosure of Invention
The invention aims to provide a cryoablation needle with high-efficiency temperature recovery and thermal therapy functions, which can realize the temperature recovery and thermal therapy without heating wires, improves the recovery efficiency and the recovery temperature upper limit compared with a gas throttling recovery mode, improves the recovery efficiency compared with a heating wire recovery mode, improves the thermal therapy effect, and avoids the problems of increased installation diameter, difficult fixation and the like caused by using the heating wires. Meanwhile, the risk of excessive ablation of extra normal tissues caused by different rewarming principles in the rewarming modes such as microwaves or radio frequency is avoided.
The technical scheme adopted by the invention is as follows:
The utility model provides a cryoablation needle with high-efficient heat recovery and thermotherapy function, includes the ablation syringe needle, the one end of ablation syringe needle is fixed with the needle bar, the inside of ablation syringe needle and needle bar is equipped with the medium conveyer pipe, still includes:
The rewarming unit is assembled in the ablation needle head;
the temperature measuring unit is assembled in the ablation needle head;
The device comprises a rewarming unit, a rewarming needle head and a medium conveying pipe, wherein the rewarming unit is connected with the ablation needle head or the medium conveying pipe, the ablation needle head has a heating function when the rewarming unit is connected with the ablation needle head, insulating films are arranged on the outer sides of the ablation needle head and the needle rod, and the medium conveying pipe has a heating function when the rewarming unit is connected with the medium conveying pipe.
In a preferred scheme, a conveying channel is formed in the medium conveying pipe, a backflow channel is separated in the ablation needle through the medium conveying pipe, and a vacuum cavity is further formed in the needle rod.
In a preferred scheme, the rewarming unit comprises a first input welding spot, a first output welding spot, a first input lead and a first output lead, wherein the first input welding spot is arranged at one end of the outer side of the medium conveying pipe, which is far away from the needle rod, the first output welding spot is arranged at one end of the outer side of the medium conveying pipe, which is far away from the ablation needle head, the first input lead and the first output lead are assembled between the ablation needle head and the medium conveying pipe, the medium conveying pipe is connected with the first input lead through the first input welding spot, and the medium conveying pipe is connected with the first output lead through the first output welding spot.
In a preferred scheme, the temperature measurement unit comprises a first temperature measurement welding spot and a first thermocouple, wherein the first temperature measurement welding spot is arranged at one end, far away from the needle rod, of the outer side of the medium conveying pipe, the first thermocouple is assembled between the ablation needle head and the medium conveying pipe, and the medium conveying pipe is connected with the first thermocouple through the first temperature measurement welding spot.
In a preferred embodiment, the needle bar is made of a hard high-resistance material with conductive performance.
In a preferred scheme, the rewarming unit comprises a second input welding spot, a second output welding spot, a second input wire and a second output wire, wherein the second input welding spot is arranged at one end of the inner wall of the ablation needle head, which is far away from the needle rod, the second output welding spot is arranged at one end of the inner wall of the ablation needle head, which is close to the needle rod, the second input wire and the second output wire are assembled between the ablation needle head and the medium conveying pipe, the ablation needle head is connected with the second input wire through the second input welding spot, and the ablation needle head is connected with the second output wire through the second output welding spot.
In a preferred scheme, the temperature measurement unit includes second temperature measurement solder joint, third temperature measurement solder joint, second thermocouple and third thermocouple, the second temperature measurement solder joint sets up in the medium conveyer pipe outside and keeps away from the one end of needle bar, the third temperature measurement solder joint sets up in the medium conveyer pipe outside and keeps away from the one end of ablation syringe needle, second thermocouple and third thermocouple all assemble between ablation syringe needle and medium conveyer pipe, just medium conveyer pipe and second thermocouple are connected through the second temperature measurement solder joint, medium conveyer pipe and third thermocouple are connected through the third temperature measurement solder joint.
In a preferred scheme, the rewarming unit includes heating structure, third input solder joint, third output solder joint, third input wire and third output wire, heating structure is fixed in the outside of ablating the syringe needle, the one end that heating structure is close to the needle bar is provided with first electrode contact and second electrode contact, the third input solder joint sets up on first electrode contact, the third output solder joint sets up on the second electrode contact, third input wire and third output wire all assemble between ablating syringe needle and medium conveyer pipe, just first electrode contact and third input wire are connected through the third input solder joint, second electrode contact and third output wire are connected through the third output solder joint.
The invention has the technical effects that:
According to the invention, the rewarming unit is arranged in the ablation needle, when the rewarming unit is connected with the ablation needle, the ablation needle has a heating function, and when the rewarming unit is connected with the medium conveying pipe, the medium conveying pipe has a heating function, so that the device can realize rewarming thermotherapy without an electric heating wire, the rewarming efficiency, the thermotherapy contact area and the rewarming temperature upper limit are improved, compared with a gas throttling rewarming mode, the rewarming efficiency and the rewarming temperature upper limit are improved, compared with an electric heating wire rewarming mode, the rewarming efficiency is improved, the thermotherapy effect is improved, and meanwhile, the problems of increased installation diameter, difficult fixation and the like caused by using the electric heating wire are avoided;
The ablation needle rewarming area and the freezing area are the same area, and the ablation needle rewarming area and the freezing area are reduced and rewarmed only by a heat conduction mode, so that the affected focus tissue ranges are the same, extra damage is avoided, the risk of excessive ablation of extra normal tissues due to different rewarming principles in the rewarming mode using microwaves or radio frequencies is avoided, and the risk born by a patient is reduced.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a cross-sectional view of the overall structure of a first embodiment of the invention;
FIG. 3 is a cross-sectional view of the overall structure of a second embodiment of the present invention;
FIG. 4 is a cross-sectional view of the overall structure of a third embodiment of the present invention;
FIG. 5 is an expanded schematic view of a horizontal structure of a heating structure in a third embodiment of the present invention;
FIG. 6 is a cross-sectional view of the overall structure of a fourth embodiment of the present invention;
FIG. 7 is an enlarged view of a portion of the invention at A in FIG. 6;
Fig. 8 is a schematic diagram illustrating a shape change of a second conductive contact according to a fourth embodiment of the present invention;
FIG. 9 is a schematic flow diagram of the gas phase working medium of the present invention;
fig. 10 is a schematic of the workflow of the present invention.
In the drawings, the list of components represented by the various numbers is as follows:
10. An ablation needle; 11. a needle bar; 12. a medium delivery tube; 13. a conveying channel; 14. a return passage; 15. a vacuum chamber;
21. A first input pad; 22. a first output pad; 23. a first input wire; 24. a first output wire; 31. a first temperature measurement welding spot; 32. a first thermocouple;
41. A second input pad; 42. a second output pad; 43. a second input lead; 44. a second output wire; 51. a second temperature measurement welding spot; 52. a third temperature measurement welding spot; 53. a second thermocouple; 54. a third thermocouple;
61. A heating structure; 62. a third input pad; 63. a third output pad; 64. a third input lead; 65. a third output wire;
71. a bushing; 72. a first conductive contact; 73. and a second conductive contact.
Detailed Description
In order that the above-recited objects, features and advantages of the present invention will become more readily apparent, a more particular description of the invention will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, but the present invention may be practiced in other ways other than those described herein, and persons skilled in the art will readily appreciate that the present invention is not limited to the specific embodiments disclosed below.
Further, reference herein to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic can be included in at least one implementation of the invention. The appearances of the phrase "in one preferred embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments.
Further, in describing the embodiments of the present invention in detail, the cross-sectional view of the device structure is not partially enlarged to a general scale for convenience of description, and the schematic is only an example, which should not limit the scope of protection of the present invention. In addition, the three-dimensional dimensions of length, width and depth should be included in actual fabrication.
Example 1
Referring to fig. 1 to 2, a first embodiment of the present invention provides a cryoablation needle with efficient heat recovery and thermal therapy functions, which includes an ablation needle 10, a needle shaft 11 is fixed at one end of the ablation needle 10, and medium delivery tubes 12 are assembled inside the ablation needle 10 and the needle shaft 11, and further includes:
a rewarming unit which is assembled inside the ablation needle 10;
the temperature measuring unit is assembled in the ablation needle head 10;
Wherein, the rewarming unit is connected with the ablation needle 10 or the medium conveying pipe 12, when the rewarming unit is connected with the ablation needle 10, the ablation needle 10 has a heating function, and when the rewarming unit is connected with the medium conveying pipe 12, the medium conveying pipe 12 has a heating function.
Here, the material of the ablation needle 10 and the medium delivery tube 12 is a hard high-resistance alloy with conductive performance, and the material may be any one of the following materials: in the present embodiment, the material of the ablation needle 10 is preferably titanium-based high resistivity alloy, wherein, when the device needs to reach the focus tissue or other special conditions through the body cavity, the material of the ablation needle 10 and the needle rod 11 can also be replaced by low temperature resistant polymer materials such as PI according to the use requirement of the ablation, and at this time, the end of the ablation needle 10 far away from the needle rod 11 is set to be a round end (the pattern of which can be shown in fig. 4).
Furthermore, the device is also provided with a power supply module, a temperature measuring module and a medium conveying module which are matched with the assembly, the power supply module is connected with the rewarming unit, the power supply module can be a direct current power supply module or an alternating current power supply module, the frequency of the alternating current power supply module is preferably below 500kHz, in the embodiment, the power supply module is preferably a direct current power supply module, the temperature measuring module is connected with the temperature measuring unit, and the medium conveying module can convey cooling medium or rewarming medium to the inside of the device.
In this embodiment, the end of the ablation needle 10 away from the needle shaft 11 is provided with a penetrating end.
Referring to fig. 9, in this embodiment, when the cryoablation is performed in the re-heating stage and the re-heating unit is connected to the medium delivery tube 12, the medium delivery module is started, the re-heating medium is input into the medium delivery tube 12, after the power supply module is started, the power supply module flows to the medium delivery tube 12 through the re-heating unit, when the current flows through the medium delivery tube 12, the electrons move directionally under the action of the electric field force and collide with the metal ions continuously, so that the electric energy is converted into heat energy, and the medium delivery tube 12 releases heat, the re-heating medium and the ablation needle 10 are heated through the medium delivery tube 12, the re-heating of the lesion tissue is performed through the ablation needle 10, and the purpose of re-heating and further inactivation of the lesion tissue is achieved at the same time, and similarly, when the re-heating unit is connected to the ablation needle 10, the current flows inside the ablation needle 10, so that the ablation needle 10 releases heat, the temperature of the ablation needle 10 is monitored through the temperature measuring unit in the process of the ablation needle 10, the temperature of the ablation needle 10 is regulated and controlled through the power supply module and the input current or voltage, the purpose of the ablation needle 10 can be realized through the above scheme without arranging an electric heating wire inside the device, the diameter of the ablation needle 10 can be further reduced while the heating efficiency is improved, the problems of increased diameter and difficult fixation of the device caused by the electric heating wire are avoided, meanwhile, the ablation needle re-warming area and the freezing area are the same area, the affected lesion tissue range is the same through the heat conduction, no additional damage is caused, the risk of reducing the patient bearing due to the difference of the working principle of radio frequency or microwave re-warming is avoided, compared with a gas throttling rewarming mode, the rewarming efficiency and the rewarming temperature upper limit are improved, compared with a heating wire rewarming mode, the rewarming efficiency is improved, the thermal therapy effect is improved, the problems of increased installation diameter, difficult fixation and the like caused by using the heating wire are avoided, and meanwhile the risk of excessive ablation of extra normal tissues caused by different rewarming principles in the use of the microwave or radio frequency rewarming mode is avoided.
Next, referring to fig. 2 again, a delivery channel 13 is provided in the medium delivery tube 12, a return channel 14 is separated from the ablation needle 10 by the medium delivery tube 12, and a vacuum chamber 15 is provided in the needle shaft 11.
Here, the medium transport module is connected to the medium transport pipe 12, and the medium transported by the medium transport module sequentially passes through the inside of the transport passage 13 and the return passage 14 and returns to the inside of the medium transport module.
Further, in the present embodiment, the material of the needle bar 11 is preferably 316L, and the needle bar 11 is fixedly connected by heat fusion, adhesion, brazing or other means by the inner and outer layers of materials.
In this embodiment, the vacuum chamber 15 is provided to keep the needle bar 11 warm, reduce heat loss, and improve the therapeutic effect, and at the same time, can avoid frosting outside the needle bar 11 during the freezing process.
Still further, referring to fig. 2, the rewarming unit includes a first input welding spot 21, a first output welding spot 22, a first input lead 23 and a first output lead 24, wherein the first input welding spot 21 is disposed at an end of the outer side of the medium delivery tube 12 far away from the needle rod 11, the first output welding spot 22 is disposed at an end of the outer side of the medium delivery tube 12 far away from the ablation needle 10, the first input lead 23 and the first output lead 24 are assembled between the ablation needle 10 and the medium delivery tube 12, the medium delivery tube 12 and the first input lead 23 are fixedly connected through the first input welding spot 21, and the medium delivery tube 12 and the first output lead 24 are fixedly connected through the first output welding spot 22.
In this embodiment, the horizontal distance between the first input welding point 21 and the first output welding point 22 is greater than or equal to 8cm in the extending direction of the medium conveying pipe 12, so as to ensure that the gas phase working medium has enough time to preheat.
Here, the first input wire 23 and the first output wire 24 are preferably conductive metals with low resistivity to reduce energy consumption on the wires, in this embodiment, the materials of the first input wire 23 and the first output wire 24 are pure silver wires, and the first input wire 23, the first input pad 21, the medium delivery pipe 12, the first output pad 22 and the first output wire 24 form a power supply path.
In this embodiment, in the cryoablation rewarming stage, the power supply module and the medium delivery module are started, the medium delivery module delivers the gas-phase working medium into the delivery channel 13, and the current sequentially passes through the first input lead 23, the first input welding point 21, the medium delivery pipe 12, the first output welding point 22 and the first output lead 24, so that the medium delivery pipe 12 heats, the gas-phase working medium is heated through the medium delivery pipe 12, and the gas-phase working medium exchanges heat with the ablation needle 10 when flowing through the interior of the backflow channel 14, so that the ablation needle 10 heats, and then the lesion tissue is rewarmed and thermally treated through the ablation needle 10.
Next, referring to fig. 2 again, the temperature measuring unit includes a first temperature measuring welding spot 31 and a first thermocouple 32, the first temperature measuring welding spot 31 is disposed at one end of the outer side of the medium delivery tube 12 far away from the needle rod 11, the first thermocouple 32 is assembled between the ablation needle 10 and the medium delivery tube 12, and the medium delivery tube 12 and the first thermocouple 32 are fixedly connected through the first temperature measuring welding spot 31.
In this embodiment, the temperature of the gas phase working medium is monitored through the first temperature measuring welding spot 31, and the monitoring signal is transmitted to the temperature measuring module, and when the temperature does not reach the expected value, the current or the voltage is adjusted through the power supply module, so that the temperature of the melting needle 10 is accurately controlled.
Example two
The embodiment is further optimized based on the first embodiment, and the difference is that the assembling mode of the rewarming unit and the temperature measuring unit is specifically that:
Referring to fig. 3, the rewarming unit includes a second input welding spot 41, a second output welding spot 42, a second input wire 43 and a second output wire 44, wherein the second input welding spot 41 is disposed at one end of the inner wall of the ablation needle 10 far away from the needle rod 11, the second output welding spot 42 is disposed at one end of the inner wall of the ablation needle 10 near the needle rod 11, the second input wire 43 and the second output wire 44 are both assembled between the ablation needle 10 and the medium conveying pipe 12, the ablation needle 10 and the second input wire 43 are fixedly connected through the second input welding spot 41, and the ablation needle 10 and the second output wire 44 are fixedly connected through the second output welding spot 42.
Here, the second input wire 43 and the second output wire 44 are preferably conductive metals with low resistivity to reduce energy consumption on the wires, in this embodiment, the materials of the second input wire 43 and the second output wire 44 are pure silver wires, and the second input wire 43, the second input pad 41, the ablation needle 10, the second output pad 42 and the second output wire 44 form a power supply path.
In this embodiment, at the stage of cryoablation technique rewarming, start power module and medium transport module, medium transport module carries gaseous phase working medium to the transport channel 13 inside, the electric current is through second input wire 43, second input solder joint 41, ablation syringe needle 10, second output solder joint 42, second output wire 44 in proper order for ablation syringe needle 10 generates heat, and then carry out the rewarming and hyperthermia to focus tissue through ablation syringe needle 10, simultaneously, absorb the heat of ablation syringe needle 10 inner wall through gaseous phase working medium, dispel the heat to ablation syringe needle 10, avoid ablation syringe needle 10 high temperature, be favorable to stable control ablation syringe needle 10's temperature.
Referring to fig. 3 again, the temperature measuring unit includes a second temperature measuring welding point 51, a third temperature measuring welding point 52, a second thermocouple 53 and a third thermocouple 54, the second temperature measuring welding point 51 is disposed at one end of the outer side of the medium conveying pipe 12 far away from the needle rod 11, the third temperature measuring welding point 52 is disposed at one end of the outer side of the medium conveying pipe 12 far away from the ablation needle 10, the second thermocouple 53 and the third thermocouple 54 are both assembled between the ablation needle 10 and the medium conveying pipe 12, the medium conveying pipe 12 and the second thermocouple 53 are fixedly connected through the second temperature measuring welding point 51, and the medium conveying pipe 12 and the third thermocouple 54 are fixedly connected through the third temperature measuring welding point 52.
In this embodiment, the temperature of one end of the ablation needle 10 is monitored by the second thermocouple 53, and the temperature of the other end of the ablation needle 10 is monitored by the third thermocouple 54, so that the temperature of the ablation needle 10 can be monitored, and the temperature of the outside of the ablation needle 10 can be prevented from being uneven.
Further, the outer sides of the ablation needle 10 and the needle shaft 11 are provided with insulating films.
Here, the insulating film is a mature application in the prior art, and the applaud edge coating is a film covering the surface of the medical instrument, so that the insulating film not only can improve the insulating performance of the instrument, but also can play a role in protecting the instrument and a patient, and is widely applied to various medical instruments, such as surgical instruments, syringes, electronic instruments and the like, and further description is omitted.
In this embodiment, the insulating film can prevent the current flowing through the ablation needle 10 from damaging the human body, thereby improving the safety performance of the device.
Example III
The difference between the material of the ablation needle 10 and the assembly mode of the rewarming unit in this embodiment is that in this embodiment, the material of the ablation needle 10 and the needle rod 11 is a low temperature resistant polymer material such as PI, the inside of the needle rod 11 is not provided with a vacuum cavity 15, and the inside of the needle rod 11 is provided with a heat insulating material, so that the surface of the needle rod is not frosted and the rewarming rod Wen Shizhen does not hurt normal tissues, and one end of the ablation needle 10 far away from the needle rod 11 is a round end, and in this embodiment:
Referring to fig. 4 to 5, the rewarming unit includes a heating structure 61, a third input welding point 62, a third output welding point 63, a third input lead 64 and a third output lead 65, the heating structure 61 is fixed on the outer side of the ablation needle 10, and a first electrode contact and a second electrode contact are disposed at one end of the heating structure 61 near the needle shaft 11. And the first electrode contact and the second electrode contact are both located inside the ablation needle 10, the third input welding point 62 is disposed on the first electrode contact, the third output welding point 63 is disposed on the second electrode contact, the third input lead 64 and the third output lead 65 are both assembled between the ablation needle 10 and the medium delivery tube 12, the first electrode contact and the third input lead 64 are fixedly connected through the third input welding point 62, and the second electrode contact and the third output lead 65 are fixedly connected through the third output welding point 63.
Further, the heating structure 61 is located inside the insulating film.
In this embodiment, in the stage of cryoablation technique rewarming, the power supply module and the medium delivery module are started, the medium delivery module delivers the gas phase working medium to the interior of the delivery channel 13, and the current sequentially passes through the third input lead 64, the third input welding point 62, the first electrode contact piece, the heating structure 61, the second electrode contact piece, the third output welding point 63 and the third output lead 65, so that the heating structure 61 heats, and then the focus tissue is subjected to rewarming and thermotherapy through the heating structure 61, and meanwhile, the gas phase working medium absorbs the heat of the inner wall of the ablation needle 10, so that the heat of the ablation needle 10 and the heating structure 61 is dissipated, the excessive temperature of the ablation needle 10 and the heating structure 61 is avoided, and the stable control of the temperature of the ablation needle 10 and the heating structure 61 is facilitated.
Example IV
The difference of this embodiment is that 70 is further disposed between the ablation needle 10 and the needle rod 11, and the 70 is connected with the rewarming unit, specifically:
Referring to fig. 6 to 8, the sleeve 71 is fixed at one end of the needle shaft 11 near the ablation needle 10, the first conductive contact 72 is fixed at the inner portion of the sleeve 71, the second conductive contact 73 is fixed at one end of the ablation needle 10 near the needle shaft 11, and the second conductive contact 73 and the first conductive contact 72 are attached in an initial state.
In this embodiment, the second output pad 42 is fixed to the outer side of the first conductive contact 72, and the first conductive contact 72 and the second output wire 44 are fixedly connected through the second output pad 42.
Further, the material of the bushing 71 is a low temperature resistant insulating material, in this embodiment, the material of the bushing 71 is preferably polytetrafluoroethylene, the material of the second conductive contact 73 is a memory alloy with high thermal conductivity and low resistivity, and a conductive path is formed among the second input wire 43, the second input pad 41, the ablation needle 10, the second conductive contact 73, the first conductive contact 72, the second output pad 42 and the second output wire 44.
Here, the modification temperature (i.e. the temperature at which the deformation occurs) of the second conductive contact 73 is customized according to the operation requirement, and in this embodiment, the modification temperature of the second conductive contact 73 is 90 ℃, and the modification temperature of the second conductive contact 73 is the same as the safety temperature threshold.
In this embodiment, in the stage of cryoablation, the power supply module and the medium delivery module are started, the medium delivery module delivers the gas-phase working medium to the interior of the delivery channel 13, the current sequentially passes through the second input lead 43, the second input welding point 41, the ablation needle 10, the second conductive contact 73, the first conductive contact 72, the second output welding point 42 and the second output lead 44, so that the ablation needle 10 heats, and then the focal tissue is subjected to the thermal treatment and the tempering by the ablation needle 10, and meanwhile, the gas-phase working medium absorbs the heat of the inner wall of the ablation needle 10, so that the ablation needle 10 dissipates heat, the temperature of the ablation needle 10 is avoided to be too high, the stable control of the temperature of the ablation needle 10 is facilitated, when the temperature of the ablation needle 10 is higher than a safe temperature threshold (namely the allergic temperature of the second conductive contact 73), the second conductive contact 73 deforms, the second conductive contact 73 is separated from the first conductive contact 72, and then the conductive path is disconnected, the ablation needle 10 is stopped from being heated, the human body is prevented from being burnt due to the too high temperature, and the safety performance of the device is improved, and when the temperature of the ablation needle 10 passes through the gas-phase working medium and is lower than the safe temperature of the second conductive contact 73, and the second conductive contact 72 is restored to the safe contact state.
Example five
Referring to fig. 10, a working method of a cryoablation needle with efficient heat recovery and thermal therapy function is applicable to any one of the above cryoablation needles with efficient heat recovery and thermal therapy function, and includes the following steps:
The first step: setting a minimum effective temperature Tmin and a maximum effective temperature Tmax of the rewarming;
and a second step of: starting a medium conveying module, conveying a cooling medium to the interior of the ablation needle 10 through a medium conveying pipe 12 for cryoablation for a duration of about 15min;
and a third step of: starting a power supply module, carrying out rewarming electric thermotherapy through a rewarming unit, and acquiring the real-time temperature Tc of the ablation needle 10 through a temperature measuring unit;
if Tc is less than Tmin, the power supply module starts a high-current mode to quickly heat the ablation needle 10;
if Tmin is less than or equal to Tc and less than or equal to Tmax, the power supply module starts a low-current mode to maintain the temperature stability of the ablation needle 10;
If Tc is greater than Tmax, the power supply module starts an alarm mode and waits for a user to process abnormality on site;
fourth step: the user can execute the repeated cooling and re-warming process according to the ablation condition so as to achieve the aim of complete ablation, and the power supply module and the medium conveying module are closed after the electrothermal therapy is finished.
Further, in this embodiment, when the power supply module enters the low current mode, the current is controlled by the PID algorithm to maintain the temperature of the ablation needle 10.
The working principle of the invention is as follows:
In this embodiment, in the stage of carrying out the rewarming in cryoablation, and when the rewarming unit is connected with medium conveyer pipe 12, start medium conveyer module, input rewarming medium to medium conveyer pipe 12 inside, after starting power module, power module flows to medium conveyer pipe 12 through the rewarming unit, when the electric current flows through medium conveyer pipe 12 inside, the electron is directional to be removed under the effect of electric field force, constantly collide with the metal ion, make the electric energy convert into heat energy, and then make medium conveyer pipe 12 release heat, heat rewarming medium and ablation syringe needle 10 through medium conveyer pipe 12, the purpose of inactivating focus tissue is realized through ablation syringe needle 10 rewarming, simultaneously, when the rewarming unit is connected with ablation syringe needle 10, the electric current flows in ablation syringe needle 10 inside, make ablation syringe needle 10 release heat, inactivate focus tissue through ablation syringe needle 10, in the rewarming process, the temperature of monitoring ablation syringe needle 10 need not to be used for the temperature of power module to adjust the regulation and control of input current or voltage realization to the temperature, through above-mentioned scheme, the inside device sets up the heating wire that can realize the deactivation, the efficiency of heating wire that can be improved, the further can also be considered, the difficult problem of heating wire that the heating needle 10 of inactivation need not to be further reduced simultaneously.
The foregoing is merely a preferred embodiment of the present invention and it should be noted that modifications and adaptations to those skilled in the art may be made without departing from the principles of the present invention, which are intended to be comprehended within the scope of the present invention. Structures, devices and methods of operation not specifically described and illustrated herein, unless otherwise indicated and limited, are implemented according to conventional means in the art.

Claims (8)

1. The utility model provides a cryoablation needle with high-efficient heat recovery and thermotherapy function, includes ablation syringe needle (10), the one end of ablation syringe needle (10) is fixed with needle bar (11), the inside of ablation syringe needle (10) and needle bar (11) is equipped with medium conveyer pipe (12), its characterized in that: further comprises:
a rewarming unit which is assembled inside the ablation needle (10);
The temperature measuring unit is assembled in the ablation needle head (10);
the device comprises a rewarming unit and a dielectric delivery pipe (12), wherein the rewarming unit is connected with the ablation needle (10) or the dielectric delivery pipe (12), when the rewarming unit is connected with the ablation needle (10), current flows through the ablation needle (10), the ablation needle (10) releases heat, insulating films are arranged on the outer sides of the ablation needle (10) and a needle rod (11), when the rewarming unit is connected with the dielectric delivery pipe (12), the current flows through the dielectric delivery pipe (12), and the dielectric delivery pipe (12) releases heat.
2. A cryoablation needle having efficient heat recovery and hyperthermia functions as defined in claim 1, wherein: the inside of medium conveyer pipe (12) has seted up conveying passage (13), the inside of ablation syringe needle (10) is separated through medium conveyer pipe (12) has backward flow passageway (14), vacuum cavity (15) have still been seted up to the inside of needle bar (11).
3. A cryoablation needle having efficient heat recovery and hyperthermia functions as defined in claim 1, wherein: the rewarming unit comprises a first input welding spot (21), a first output welding spot (22), a first input lead (23) and a first output lead (24), wherein the first input welding spot (21) is arranged at one end of the outer side of the medium conveying pipe (12) far away from the needle bar (11), the first output welding spot (22) is arranged at one end of the outer side of the medium conveying pipe (12) far away from the ablation needle head (10), the first input lead (23) and the first output lead (24) are assembled between the ablation needle head (10) and the medium conveying pipe (12), the medium conveying pipe (12) and the first input lead (23) are connected through the first input welding spot (21), and the medium conveying pipe (12) and the first output lead (24) are connected through the first output welding spot (22).
4. A cryoablation needle having efficient heat recovery and hyperthermia functions as defined in claim 1, wherein: the temperature measurement unit comprises a first temperature measurement welding spot (31) and a first thermocouple (32), wherein the first temperature measurement welding spot (31) is arranged at one end, far away from a needle rod (11), of the outer side of a medium conveying pipe (12), the first thermocouple (32) is assembled between an ablation needle head (10) and the medium conveying pipe (12), and the medium conveying pipe (12) and the first thermocouple (32) are connected through the first temperature measurement welding spot (31).
5. A cryoablation needle having efficient heat recovery and hyperthermia functions as defined in claim 1, wherein: the needle bar (11) is made of a hard high-resistance material with conductivity.
6. A cryoablation needle having efficient heat recovery and hyperthermia functions as defined in claim 1, wherein: the rewarming unit comprises a second input welding spot (41), a second output welding spot (42), a second input lead (43) and a second output lead (44), wherein the second input welding spot (41) is arranged at one end of the inner wall of the ablation needle head (10) far away from the needle rod (11), the second output welding spot (42) is arranged at one end of the inner wall of the ablation needle head (10) close to the needle rod (11), the second input lead (43) and the second output lead (44) are assembled between the ablation needle head (10) and the medium conveying pipe (12), the ablation needle head (10) and the second input lead (43) are connected through the second input welding spot (41), and the ablation needle head (10) and the second output lead (44) are connected through the second output welding spot (42).
7. A cryoablation needle having efficient heat recovery and hyperthermia functions as defined in claim 1, wherein: the temperature measurement unit comprises a second temperature measurement welding spot (51), a third temperature measurement welding spot (52), a second thermocouple (53) and a third thermocouple (54), wherein the second temperature measurement welding spot (51) is arranged at one end, far away from a needle rod (11), of the outer side of a medium conveying pipe (12), the third temperature measurement welding spot (52) is arranged at one end, far away from an ablation needle head (10), of the outer side of the medium conveying pipe (12), the second thermocouple (53) and the third thermocouple (54) are assembled between the ablation needle head (10) and the medium conveying pipe (12), the medium conveying pipe (12) and the second thermocouple (53) are connected through the second temperature measurement welding spot (51), and the medium conveying pipe (12) and the third thermocouple (54) are connected through the third temperature measurement welding spot (52).
8. A cryoablation needle having efficient heat recovery and hyperthermia functions as defined in claim 1, wherein: the rewarming unit comprises a heating structure (61), a third input welding spot (62), a third output welding spot (63), a third input lead (64) and a third output lead (65), wherein the heating structure (61) is fixed on the outer side of an ablation needle head (10), one end, close to a needle rod (11), of the heating structure (61) is provided with a first electrode contact and a second electrode contact, the third input welding spot (62) is arranged on the first electrode contact, the third output welding spot (63) is arranged on the second electrode contact, the third input lead (64) and the third output lead (65) are assembled between the ablation needle head (10) and a medium conveying pipe (12), the first electrode contact and the third input lead (64) are connected through the third input welding spot (62), and the second electrode contact and the third output lead (65) are connected through the third output welding spot (63).
CN202311534148.9A 2023-11-17 2023-11-17 Cryoablation needle with efficient heat recovery and thermal therapy functions Active CN117338398B (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107714172A (en) * 2017-11-10 2018-02-23 上海导向医疗系统有限公司 Thermometric and the cryoablation pin of rewarming function are realized by thermocouple wire simultaneously
CN107997818A (en) * 2017-11-10 2018-05-08 上海导向医疗系统有限公司 The cryoablation pin of rewarming and thermotherapeutic function is realized by electric heating wire
CN209847360U (en) * 2019-02-28 2019-12-27 上海导向医疗系统有限公司 Split type conductive structure of flexible cryoablation needle
CN112263322A (en) * 2020-09-29 2021-01-26 杭州睿笛生物科技有限公司 Tumor ablation needle with blood coagulation function
CN114886539A (en) * 2022-04-22 2022-08-12 上海导向医疗系统有限公司 Control device for ablation and ablation assembly
CN115005963A (en) * 2022-05-26 2022-09-06 上海导向医疗系统有限公司 Low-temperature treatment system based on precooling of cryogenic refrigerator
CN218075189U (en) * 2021-06-30 2022-12-20 杭州堃博生物科技有限公司 Rewarming system for cryoablation

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107714172A (en) * 2017-11-10 2018-02-23 上海导向医疗系统有限公司 Thermometric and the cryoablation pin of rewarming function are realized by thermocouple wire simultaneously
CN107997818A (en) * 2017-11-10 2018-05-08 上海导向医疗系统有限公司 The cryoablation pin of rewarming and thermotherapeutic function is realized by electric heating wire
CN209847360U (en) * 2019-02-28 2019-12-27 上海导向医疗系统有限公司 Split type conductive structure of flexible cryoablation needle
CN112263322A (en) * 2020-09-29 2021-01-26 杭州睿笛生物科技有限公司 Tumor ablation needle with blood coagulation function
CN218075189U (en) * 2021-06-30 2022-12-20 杭州堃博生物科技有限公司 Rewarming system for cryoablation
CN114886539A (en) * 2022-04-22 2022-08-12 上海导向医疗系统有限公司 Control device for ablation and ablation assembly
CN115005963A (en) * 2022-05-26 2022-09-06 上海导向医疗系统有限公司 Low-temperature treatment system based on precooling of cryogenic refrigerator

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