CN217428921U - Intelligent experimental animal feeding cage with radiation shielding function - Google Patents
Intelligent experimental animal feeding cage with radiation shielding function Download PDFInfo
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- CN217428921U CN217428921U CN202120969816.0U CN202120969816U CN217428921U CN 217428921 U CN217428921 U CN 217428921U CN 202120969816 U CN202120969816 U CN 202120969816U CN 217428921 U CN217428921 U CN 217428921U
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry
Abstract
The utility model discloses an intelligent experimental feeding cage with radiation shielding function, belonging to the technical field of experimental study of radiopharmaceutical animals, which comprises a shell, wherein a plurality of observation bins for placing experimental animals are arranged inside the shell, a containing hole for installing radiation shielding materials is arranged between the observation bins, an intelligent operation panel 2 is arranged outside the shell, and an air supply filtering device and an exhaust filtering device are arranged at the top of the shell; the observation bin comprises an air supply port, an air exhaust port, an observation window, a shielding door, a video monitoring module and an intelligent monitoring control module. The utility model discloses have radiation shield, intelligent monitoring control and video monitoring's function, can effectively reduce the radiation influence of the internal radionuclide of animal to experimenter and other experimental animals, improve the reliability of experiment conclusion.
Description
Technical Field
The utility model belongs to the technical field of radiopharmaceutical animal experiment research, specifically be an intelligent experimental animals rearging cage utensil with radiation shielding function.
Background
In the research and development process of radiopharmaceuticals, the safety evaluation research before clinic is a key link in the research and development process of new drugs, and determines whether the new drugs can enter clinical application. In the study of the evaluation of the preclinical safety of radiopharmaceuticals, guinea pigs, rabbits, and the like are often selected as test subjects. The radioactive drug is injected into a test animal body through veins and other ways, the test animal is placed in a cage, the toxicity, acute radioactive toxicity symptoms, the degree of toxicity, recovery and death conditions and the like which may appear under the whole body exposure condition of the animal are observed, the safety and distribution condition of the drug are evaluated, the information related to the excessive acute toxicity of the drug is known, and a reference basis is provided for the preclinical safety evaluation and the initial dose design of clinical medication of the drug. After the test animals are administered, researchers must regularly observe toxicity symptoms, such as toxicity reactions in the animals, death of the animals, and the like. The fundamental difference between radiopharmaceuticals and non-radiopharmaceuticals is their radioactivity, and radiation dose management has been a constant concern for researchers in preclinical evaluation of radiopharmaceuticals. After the medicine is injected into the animal body, the animal body is equivalent to a movable radioactive source, and certain ionizing radiation harm can be caused to research personnel.
However, the current animal cage is mostly hollow, and the cage is hollow all around and does not have radiation shielding, real-time temperature and humidity detection and radiation monitoring functions. According to radiation monitoring data of animal experiments of previous times, the surface dose rate of the cage can sometimes reach dozens of MuSv/h, and testers can be damaged by certain radiation when contacting the cage in a close range. In addition, radiation effects can occur between animals, and can have uncertain or unpredictable effects on the outcome of the test.
Disclosure of Invention
For solving the defect that prior art exists, the utility model aims at providing an intelligent experiment rearging cage utensil with radiation shielding function has radiation shielding, intelligent monitoring control and video monitoring's function, can effectively reduce the radiation influence of radionuclide in the animal body to experimenter and other experimental animals, improves the reliability of experiment conclusion.
In order to achieve the above purpose, the utility model adopts a technical scheme that:
an intelligent experiment feeding cage with a radiation shielding function comprises a shell, wherein a plurality of observation cabins for placing experimental animals are arranged in the shell, radiation shielding material accommodating holes for installing radiation shielding materials are formed between the observation cabins, an intelligent operation panel is arranged outside the shell, and an air feeding filtering device and an exhaust filtering device are arranged at the top of the shell;
the observation bin comprises an air supply port, an exhaust port, an observation window, a shielding door, a video monitoring module and an intelligent monitoring control module.
Further, the intelligent experimental feeding cage with radiation shielding function as described above, wherein the intelligent operation panel is used for displaying and setting the temperature, humidity and air pressure in each observation bin, setting the air supply flow rate of the air supply filtering device and the exhaust flow rate of the exhaust filtering device.
Further, according to the intelligent experiment feeding cage with the radiation shielding function, the air supply filtering device filters the outside air according to the air supply flow rate and then feeds the outside air into each observation cabin.
Further, in the intelligent experimental rearing cage with the radiation shielding function, the exhaust filtering device filters and exhausts the exhaust gas in the observation bin according to the exhaust flow rate.
Further, the intelligent experiment rearing cage with the radiation shielding function determines the thickness of the radiation shielding material in the radiation shielding material accommodating hole based on the experiment conditions and the simulation calculation results.
Further, according to the intelligent experimental feeding cage with the radiation shielding function, the air supply hole is communicated with the air supply filtering device through the air supply channel, and the air exhaust hole is communicated with the exhaust filtering device through the exhaust channel.
Furthermore, as above intelligent experiment rearging cage utensil with radiation shielding function, intelligent monitoring control module includes radiation monitoring probe, temperature and humidity sensor, baroceptor, microprocessor, heating device and humidification device.
Further, as above intelligent experiment feeding cage utensil with radiation shielding function, the intelligent monitoring control module gathers each in real time the status parameter of observing the storehouse, with status parameter transmission to the intelligence operation panel on show to through communication bus with data transmission to other equipment terminals, when the status parameter that the intelligent monitoring control module gathered is less than the threshold value of setting, the heating device, the humidification device, the filter equipment that supplies gas or exhaust filter equipment begins work until satisfying the threshold value of setting.
Furthermore, as above intelligent experiment feeding cage utensil with radiation shielding function, the casing bottom still is provided with the universal wheel.
Further, as for the intelligent experimental rearing cage with the radiation shielding function, the number of the observation bins is six.
The beneficial effects of the utility model are as follows:
compared with the traditional existing rearing cage, the utility model has the radiation shielding function, reduces the irradiated dose of researchers, reduces the radiation interference between experimental animals and ensures the certainty of experimental conclusion; the intelligent monitoring control module can continuously record and store experimental data for 24 hours, and provides complete and reliable experimental data for the evaluation of researchers; the video monitoring module can be used for researchers to remotely observe the reaction of the animals after drug administration in real time, and the time for the researchers to contact the animals in a close range is avoided or reduced.
Drawings
Fig. 1 is a schematic structural view of an embodiment of an intelligent experimental rearing cage with radiation shielding function according to the present invention;
FIG. 2 is a side view of the embodiment of FIG. 1;
wherein, 1-shell; 2-an intelligent operation panel; 3-air supply filtering device; 4-exhaust gas filtration means; 5-universal wheels; 6, an observation bin; 7-radiation shielding material containing hole; 61-air supply port; 62-an exhaust port; 63-a viewing window; 64-a screen door; 65-video monitoring module; and 66-intelligent monitoring control module.
Detailed Description
The invention is further described with reference to specific embodiments and drawings attached to the description.
Fig. 1 shows a structural schematic diagram of an intelligent experiment feeding cage utensil embodiment with radiation shielding function, fig. 2 shows fig. 1 the side view of embodiment can be seen from the picture, this feeding cage utensil includes casing 1, 1 inside a plurality of observation storehouses 6 that are used for placing experimental animals that are provided with of casing, be provided with radiation shielding material holding hole 7 between each observation storehouse 6, the radiation shielding material is installed to radiation shielding material holding hole 7 in, 1 side of casing is provided with intelligent operating panel 2, 1 top of casing is provided with air feed filter equipment 3 and exhaust filter equipment 4, 1 bottom of casing still is provided with universal wheel 5, the experiment feeding cage utensil of being convenient for removes experimental position.
The smart operation panel 2 is used to display the radiation dose rate, set the temperature, humidity, and air pressure in each observation cabin 6, and set parameters, such as the flow rate, of the air supply filter device 3 and the exhaust filter device 4.
The air supply filter device 3 is used for filtering the outside air and then feeding the filtered outside air into the observation bin 6. The intelligent operation panel 2 is used for setting the air supply flow rate of the air supply filtering device 3, and the air supply filtering device 3 filters the outside air and then sends clean air into each observation cabin 6 according to the set flow rate for the experimental animal to breathe.
The exhaust gas filtering device 4 is used for treating and discharging the gas in the observation cabin 6. The exhaust flow rate of the exhaust filtering device 4 is set through the intelligent operation panel 2, and the exhaust filtering device 4 filters the exhaust gas exhaled by the experimental animals in each observation bin 6 according to the set flow rate and then exhausts the exhaust gas, so that the gas with radioactive particles is prevented from being exhausted into the air.
The radiation shielding material accommodating holes 7 are used for assembling radiation shielding layers, and radiation shielding materials with different thicknesses can be assembled in the radiation shielding material accommodating holes 7 among the observation bins 6 according to different experimental conditions and simulation calculation results, so that a radiation shielding function is realized, radiation influence among animals is reduced, and uncertainty and influence which cannot be estimated caused by experimental conclusions are avoided.
In this embodiment, this intelligent experiment rearging cage has set up six observation storehouses 6, can hold six animals simultaneously and experiment. Each observation bin 6 comprises an air supply port 61, an air exhaust port 62, an observation window 63, a shielding door 64, a video monitoring module 65 and an intelligent monitoring control module 66.
Wherein, the air feeding hole 61 is communicated with the air feeding filter device 3 positioned at the top of the shell 1 through an air feeding channel to feed clean air for the experimental animal.
The exhaust port 62 is communicated 4 with an exhaust filtering device at the top of the housing 1 through an exhaust passage, and exhausts the exhaust gas exhaled by the experimental animal after being filtered by the exhaust filtering device 4.
The shielding door 64 can isolate the observation bin 6 from the external environment, and certain radiation hazard is avoided when researchers closely observe experimental animals.
The observation window 63 allows the researcher to observe the condition of the experimental animal.
The video monitoring module 65 can transmit real-time video pictures in each observation bin 6 to the terminal equipment through the microprocessor, and researchers can remotely observe the reaction of the animals after drug administration in real time through the terminal equipment, so that the time of contacting the animals at a short distance is avoided or reduced.
The intelligent monitoring control module 66 comprises a radiation monitoring probe, a temperature and humidity sensor, an air pressure sensor, a microprocessor, a heating device and a humidifying device, can transmit the state parameters collected in each observation bin 6 in real time to the intelligent operation panel 2 for display, and transmits data to other equipment terminals through a communication bus. Researchers can transfer the state parameters of the observation cabin at any time through the intelligent control terminal to carry out data analysis, and when the state parameters collected by the sensor are lower than the set threshold, the heating device, the humidifying device, the air supply filtering device 3 or the exhaust filtering device 4 work until the set threshold is met. In the embodiment, the radiation monitoring probe adopts a small Geiger counter tube, and has a compact structure and is easy to assemble; the temperature and humidity sensor selects SHT30 to transmit temperature and humidity data to the microprocessor through an IIC bus; the model of the air pressure sensor is BMP180, and the air pressure sensor has the characteristics of high precision, small volume and ultralow energy consumption; the microprocessor selects ARM, is used for processing and storing all the acquired state parameters of the observation cabin, and transmits the state parameters to the intelligent control end for display; the heating device adopts a silicon rubber heating plate; the humidifying device uses an atomizing sheet for humidifying.
The utility model provides an intelligent experiment rearging cage with radiation shielding function, has the radiation shielding function, reduces the irradiated dosage of researchers, reduces the radiation interference between experimental animals, and ensures the certainty of experimental conclusion; the intelligent monitoring control module can continuously record and store experimental data for 24 hours, and provides complete and reliable experimental data for the evaluation of researchers; the video monitoring module can be used for researchers to remotely observe the reaction of the animals after drug administration in real time, and the time for the researchers to contact the animals in a close range is avoided or reduced.
The above-described embodiments are merely illustrative of the present invention, which may be embodied in other specific forms or in other specific forms without departing from the spirit or essential characteristics thereof. The described embodiments are, therefore, to be considered in all respects as illustrative and not restrictive. The scope of the invention should be determined by the appended claims, and any changes that are equivalent to the intent and scope of the claims are intended to be embraced therein.
Claims (10)
1. An intelligent experimental animal feeding cage with a radiation shielding function is characterized by comprising a shell (1), wherein a plurality of observation cabins (6) for placing experimental animals are arranged in the shell (1), radiation shielding material containing holes (7) for installing radiation shielding materials are arranged between the observation cabins (6), an intelligent operation panel (2) is arranged outside the shell (1), and an air feeding filtering device (3) and an exhaust filtering device (4) are arranged at the top of the shell (1);
the observation bin (6) comprises an air supply port (61), an exhaust port (62), an observation window (63), a shielding door (64), a video monitoring module (65) and an intelligent monitoring control module (66).
2. The intelligent laboratory animal feeding cage with radiation shielding function according to claim 1, wherein said intelligent operation panel (2) is used for displaying and setting temperature, humidity and air pressure in each observation bin (6), setting air supply flow rate of said air supply filter device (3) and exhaust flow rate of said exhaust air filter device (4).
3. The intelligent experimental animal feeding cage with radiation shielding function as claimed in claim 2, wherein the air-feeding filtering device (3) filters the external air according to the air-feeding flow rate and feeds the filtered air into each observation bin (6).
4. The intelligent laboratory animal feeding cage with radiation shielding function according to claim 2, wherein said exhaust filtering means (4) filters the exhaust gas in said observation cabin (6) according to the exhaust flow rate and then discharges the filtered exhaust gas.
5. The intelligent experimental animal feeding cage with radiation shielding function according to any one of claims 1 to 4, wherein the thickness of the radiation shielding material in the radiation shielding material containing hole (7) is determined based on experimental conditions and simulation calculation results.
6. The intelligent laboratory animal feeding cage with radiation shielding function according to claim 1, wherein said air feeding port (61) is communicated with said air feeding filtering device (3) through an air feeding channel, and said air discharging port (62) is communicated with said air discharging filtering device (4) through an air discharging channel.
7. The intelligent experimental animal feeding cage with the radiation shielding function as claimed in claim 6, wherein the intelligent monitoring control module (66) comprises a radiation monitoring probe, a temperature and humidity sensor, an air pressure sensor, a microprocessor, a heating device and a humidifying device.
8. The intelligent laboratory animal feeding cage with the radiation shielding function according to claim 7, wherein the intelligent monitoring control module (66) collects the status parameters of each observation cabin (6) in real time, transmits the status parameters to the intelligent operation panel (2) for display, and transmits the data to other equipment terminals through a communication bus, and when the status parameters collected by the intelligent monitoring control module (66) are lower than a set threshold, the heating device, the humidifying device, the air supply filtering device (3) or the exhaust filtering device (4) starts to work until the set threshold is met.
9. The intelligent experimental animal feeding cage with radiation shielding function as claimed in claim 1, wherein the bottom of the housing (1) is further provided with universal wheels (5).
10. The intelligent laboratory animal feeding cage with radiation shielding function according to claim 1, characterized in that the number of said observation bins (6) is six.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202120969816.0U CN217428921U (en) | 2021-05-08 | 2021-05-08 | Intelligent experimental animal feeding cage with radiation shielding function |
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| CN202120969816.0U CN217428921U (en) | 2021-05-08 | 2021-05-08 | Intelligent experimental animal feeding cage with radiation shielding function |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116034892A (en) * | 2023-04-03 | 2023-05-02 | 北京先通国际医药科技股份有限公司 | Radiation-proof living animal storage cabinet and application thereof |
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2021
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116034892A (en) * | 2023-04-03 | 2023-05-02 | 北京先通国际医药科技股份有限公司 | Radiation-proof living animal storage cabinet and application thereof |
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