CN103142232A - Expiration sampling device and application method thereof - Google Patents
Expiration sampling device and application method thereof Download PDFInfo
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- CN103142232A CN103142232A CN 201310023027 CN201310023027A CN103142232A CN 103142232 A CN103142232 A CN 103142232A CN 201310023027 CN201310023027 CN 201310023027 CN 201310023027 A CN201310023027 A CN 201310023027A CN 103142232 A CN103142232 A CN 103142232A
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Abstract
The invention provides an expiration sampling device which is used for diagnosing diseases by a 14C marked expiration test and is particularly used for diagnosing helicobacter pylori infection by a 14C-urea expiration test, and an application method thereof. The sampling device comprises a pipe-shaped component provided with a gas outlet, a gas inlet, an absorption assembly and an air flow channel; the pipe-shaped component is internally further provided with a scintillation assembly; one part of the air flow channel is formed by a gap between the absorption assembly and the scintillation assembly; when expired air flows through the air flow channel, CO2 in the expired air is absorbed by the absorption assembly; if the absorption assembly absorbing the CO2 contains 14CO2, beta grains generated by decaying pass through the air flow channel to be knocked on the scintillation assembly; and a scintillation body on the scintillation assembly generates scintillation light recorded by a scintillation counting device.
Description
Affiliated technical field
The present invention relates to a kind of
14the C-carbon dioxide (
14cO
2) sampling apparatus and the using method thereof of gas, for medical domain
14c labelling breath test diagnoses the illness, especially for
14specimen of breath collection and the measurement of C-urea breath test diagnosing helicobacter pylori infection.
Background technology
Breath test has been widely used in the diagnosis of some disease of medical domain, when giving the experimenter, takes specifically
14after the C labelled compound, because the reason of disease can cause the change of metabolic pathway, it one of changes is the metabolite of discharging via exhaling
14the C-carbon dioxide (
14cO
2) amount can there are differences, the carbon dioxide in gather exhaling, measure wherein
14the radioactivity of C, whether diagnosable disease exists and degree.For example, be subject to the patient of helicobacter pylori infections oral
14during C-carbamide, because one of feature of helicobacter pylori is that it produces in human body non-existent urease originally, urease can by
14c-urea decomposition and producing
14cO
2,
14cO
2excrete from expiration, gather the CO that patient breathes out
2gas is also measured wherein
14cO
2content (
14the radiation activity of C), will be far away higher than infection population not, this is that the person is not oral because infect the helicobacter pylori
14after C-carbamide,
14c-carbamide will be discharged from urine with prototype, rather than from exhale, discharge after being decomposed
14cO
2.
For
14collection and the measurement of C labelling breath test sample, one of prior art is alkali compounds to be dissolved in to methanol solution and the CO that forms
2absorbent is placed in scintillation vial, and the gas that the experimenter breathes out passes into absorbent solution through a tubule that inserts solution, adds scintillation solution in the absorbent that has absorbed carbon dioxide sample again, then by liquid scintillation counter, measures the radioactivity of sample.
Chinese patent 97180427.3 and Chinese patent 02207235.7 disclose sampling apparatus and the measuring method of another kind of type, this sampling apparatus comprises a tubular member with gas access, gas outlet, the solid CO that has been fixed on loading in tubular member
2the absorbent assembly of absorbent.When breath passes through tubular member, absorbent assembly in gas channel in tubular member will absorb the carbon dioxide in exhaling, in the measuring device that the Geiger Miller counter tube of after sampling finishes, the sampling apparatus insertion being take is sensor, make absorbent assembly near sensor
14the beta-particle that the C decay produces strikes on the window of Geiger Miller counter tube, causes recordable discharge signal, thereby analyze, obtains in sample
14the content of C.
Above-mentioned two kinds of methods all have deficiency in clinical practice, the former has higher detection efficient when measuring, but must use the organic solutions such as poisonous methanol, toluene, during the shortcoming of existence such as sampling easily by absorbent solution suck-back entrance, easily splash, contaminated environment, troublesome poeration etc.Although the latter has adopted solid absorbent, there is no above-mentioned shortcoming,
14what the C decay discharged is low energy beta rays, detection efficient while measuring with Geiger Miller counter tube is lower, too high background counting rate is arranged again, in limited Measuring Time simultaneously, the statistic fluctuation of background count can, higher than the decay signals counting of a part of sample, therefore reduce the credibility of measuring.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of expiration sampling apparatus and using method thereof that comprises absorbent assembly and flickering unit, after gathering specimen of breath with this sampling apparatus, insert the scintillation counter measurement of glimmering, the suck-back of having avoided prior art to exist, easily splash, the shortcoming of contaminated environment, troublesome poeration, there is again higher measurement credibility simultaneously.
The technical solution adopted for the present invention to solve the technical problems is: in a tubular member with gas access, gas outlet and gas channel, except thering is absorbent assembly, also there is the flickering unit be oppositely arranged with absorbent assembly, contain solid scintillator, gap between absorbent assembly and flickering unit forms the part of gas channel or gas channel, when expiratory flow is crossed gas channel, the absorbent assembly of will inevitably flowing through, the absorbent that carbon dioxide in expiration is absorbed on assembly absorbs, and sampling process is achieved.Absorbed CO in expiration
2if absorbent assembly on contain
14cO
2,
14the part beta-particle that the C decay produces will be crossed gas channel and strike on flickering unit, after absorbing Beta-ray energy, the contained scintillator of flickering unit produces passage of scintillation light, the sensor that the passage of scintillation light produced is delivered to scintillation counter by flickering unit and shell carries out record, in order to increase CO
2absorbtivity and raising detection efficient, under the prerequisite of taking into account the passage of scintillation light transmission efficiency, can also be used a plurality of independently absorbent assemblies and flickering unit interleaved to stack.
Absorbent assembly can be used a kind of alkaline-resisting material as supporter according to prior art, and on it, absorption or adhesion alkali compounds are as CO
2absorbent.Absorbent can adopt the solid alkaline compounds such as sodium hydroxide, calcium hydroxide, Lithium hydrate, these compound dissolutions are formed to aqueous slkali in water or alcohol, aqueous slkali is coated on supporter, fully after drying, solid base being adsorbed on supporter forms absorbent assembly, also can the solid alkaline compound of pulverulence be bonded in by binding agent to the surface of supporter.CO
2can also be added with the macromolecule amine that helps improve absorbent properties, surfactant, hygroscopic agent etc. in absorbent.
The shell of flickering unit and tubular member should be all printing opacity or leaded light, whole or its surperficial solid scintillator that contains of flickering unit, solid scintillator can be other solid scintillators of commodity plastic scintillant or similar performance, and the shell of tubular member also can contain scintillator and have the function of flickering unit simultaneously.Background counting rate when flicker is measured and the volume of scintillator are proportionate, and the volume that reduces scintillator can reduce background counting rate, due to
14during the C decay, the β ray of emission is low energy charged particle, in density, is about 1g/cm
3the scintillator medium in, the about 0.3mm of its penetration range, only have the scintillator of the about 0.3mm thickness in top layer to work, and therefore, scintillator fried batter in a thin layer or thin-wall construction, can under the prerequisite that affects hardly counting efficiency, effectively reduce background counting rate.
In order to control sampling quantity, independently sampling quantity is basic identical each time to make each experimenter, and an independently indication component can also be set in gas channel, and this indication component is by the metachromasia indication sampling terminal of acid-base indicator.
Carry out in the process of specimen of breath collection the solid CO on absorbent assembly at sampling apparatus
2absorbent more is conducive to CO under moistening state
2the absorption of gas, although the steam comprised in expiration contributes to dry CO
2absorbent becomes moisture state, but, when measuring sample, excessive moisture will hinder the β ray particle from CO
2escape out in absorbent, reduce detection efficient, therefore be necessary to prevent that the experimenter is blown into a large amount of salivas in sampling apparatus, cause CO
2the water content of absorbent surpasss the expectation.
Can access a saliva isolator on the gas access of sampling apparatus, the saliva isolator has certain volume and holds saliva, prevents that a large amount of salivas from entering in sampling apparatus.The saliva isolator can be the part of sampling apparatus, with sampling apparatus, be combined as a whole, can be also an independently disposable unit, be connected with sampling apparatus by the mode of pegging graft before using, sampling separates the saliva isolator after finishing again from sampling apparatus.
The invention provides a kind of for
14the C breath test diagnoses the illness, especially for
14the using method of the expiration sampling apparatus of C-urea breath test diagnosing helicobacter pylori infection, except allowing the experimenter take
14outside the medicine of C labelling, also comprise following process:
The first step: the experimenter exhales to the gas access of sampling apparatus of the present invention, this device comprises a tubular member with gas access, gas outlet and gas channel, also comprise absorbent assembly and the flickering unit that contains solid scintillator in cast structure member, gap between absorbent assembly and flickering unit forms the part of gas channel or gas channel, also be provided with an indication component that is used to refer to the sampling terminal in gas channel, the part that the saliva isolator can be used as sampling apparatus is connected on its gas access.
Second step: the change color of observing indication component.
The 3rd step: stop after the color of reaching home exhaling.
The 4th step: if be connected with independently the saliva isolator on sampling apparatus both are separated.
The 5th step: sampling apparatus is inserted in the measuring chamber of scintillation counter, in sample
14when the beta-particle that the C decay produces strikes the flickering unit corresponding with absorbent assembly, the scintillator on flickering unit is excited, can be by the passage of scintillation light of the photomultiplier tube of scintillation counter record thereby produce.
The 6th step: the measurement data of measurement result and Healthy People is compared.
The accompanying drawing explanation
Fig. 1 is the structural representation that first embodiment of sampling apparatus of the present invention therefrom cuts open.
Fig. 2 is the A-A cutaway view of first embodiment of sampling apparatus of the present invention.
Fig. 3 is the structural representation that second embodiment of sampling apparatus of the present invention therefrom cuts open.
Fig. 4 is the principle schematic of second embodiment of sampling apparatus of the present invention when measuring state.
Fig. 5 is the structural representation that the shell of the 3rd embodiment of sampling apparatus of the present invention is therefrom cut open.
Fig. 6 is the schematic appearance of the 4th embodiment of sampling apparatus of the present invention.
Fig. 7 is the outline drawing of first embodiment of sampling apparatus saliva isolator of the present invention.
Fig. 8 is the structural representation of first embodiment of sampling apparatus saliva isolator of the present invention.
Fig. 9 is the outline drawing of second embodiment of sampling apparatus saliva isolator of the present invention.
Figure 10 is the structural representation of second embodiment of sampling apparatus saliva isolator of the present invention.
Figure 11 is that sampling apparatus of the present invention is put into the schematic diagram that scintillation counter is measured.
In figure: 1. absorbent assembly, 2. flickering unit, 2a. base layer, 2b. scintillator layers, 3. gas channel, 4. shell, 4a. the sampling apparatus gas access, 4b. sampling apparatus gas outlet, 4c. location structure, 5. indication component, 6. sampling apparatus, 7. saliva isolator, 7a. saliva isolator cavity, 7b. saliva isolator air inlet pipe, 7c. saliva isolator escape pipe, 7d. saliva isolator escape pipe is suitable for reading, 7e. saliva isolator escape pipe residing horizontal plane suitable for reading, 7f. water storage cavity, 8. scintillation counter measuring chamber.
The specific embodiment
See figures.1.and.2, both are staggered relatively for absorbent assembly 1 and flickering unit 2, gap between the two, formed the part of the gas channel 3 of sampling apparatus, be that gas channel 3 has comprised the part of guiding function and the passage that the gap between absorbent assembly and flickering unit forms, flickering unit 2 is shaped components of commodity plastic scintillant material, the shell 4 of sampling apparatus is by same plastic scintillant materials processing molding and has the tubular member of the 4b of gas access 4aHe gas outlet, therefore the part of shell 4 has also formed flickering unit 2, while gathering specimen of breath, expiration enters from gas access 4a, the gas channel 3 of flowing through, from the 4b of gas outlet, flow out again, absorbent assembly 1 by the polyurethane foam material of porous as supporter, the saturated aqueous solution of dipping or spraying Lithium hydrate on supporter, in the environment of isolated carbon dioxide, drying is removed moisture content subsequently, Lithium hydrate is adsorbed on the surface pore of supporter, the expiratory flow absorbent assembly 1 of will inevitably flowing through when gas channel 3, CO in expiration
2the Lithium hydrate that can be absorbed on assembly 1 absorbs.
With reference to Fig. 3, in the present embodiment, flickering unit 2 is composited by the scintillator layers 2b on base layer 2a and its outer surface, and base layer 2a is made by the pmma material of leaded light or printing opacity, can be processed according to the requirement of structural strength and leaded light efficiency.The commodity plastic scintillant is dissolved in the organic solvent such as toluene and forms a kind of scintillator lysate, be coated in type base layer surface, treat that the solvent evaporates after fixing is the scintillator coating, form scintillator layers 2b, after also the commodity plastic scintillant can being heated into to molten mass, as coating, applied, cooling after fixing forms scintillator layers 2b, and therefore scintillator layers 2b can do very thinly to reduce background counting rate.Shell 4 also adopts the material of leaded light or printing opacity to make, and shell 4 also can cover scintillator layers 2b and form flickering unit 2 simultaneously, the flickering unit of this base layer and scintillator layers composite construction, both meet the conduction efficiency requirement of structural strength and the passage of scintillation light of flickering unit, and effectively reduced the volume of scintillator.
Also be provided with an indication component 5 in gas channel 3, indication component 5 adopts alkaline-resisting polypropylene fiber non-woven fabrics as supporter, flooded the aqueous solution that contains 0.3% thymolphthalein and 4% Lithium hydrate, in the expiration sampling process, the alkaline hydrogen lithium oxide on indication component 5 also absorbs the CO in exhaling simultaneously
2and be consumed, changed the pH value on the supporter, cause the color change that the color of thymol phthalein indicator becomes colorless from blueness, the change color of indication component is observed by transparent outer cover or transparent window, thus indication sampling terminal.
With reference to Fig. 4, gathered the sampling apparatus of specimen of breath, its absorbent assembly 1 has absorbed the CO in exhaling
2if wherein contain
14cO
2,
14the β ray particle that the C decay produces is crossed the gap between absorbent assembly 1 and flickering unit 2 by some, strike on flickering unit 2, the scintillator that flickering unit 2 comprises is excited and produces passage of scintillation light, passage of scintillation light can be by transparent or leaded light flickering unit 2 to all directions transmission, and by the shell 4 of printing opacity or leaded light, be delivered on the photosurface of two photomultiplier tubes staggered relatively, gauge provides the radiation activity of sample by the pulse analysis counting circuit simultaneously.
With reference to Fig. 5, for the measuring chamber of the liquid scintillation counter with general is complementary, sampling apparatus adopts the cylinder blanket 4 same with the standard scintillation vial, and shell 4 is that the material by printing opacity or leaded light forms, absorbent assembly 1 and flickering unit 2 are middle porose cake (sheet) shape, a plurality of absorbent assemblies 1 and flickering unit 2 interleaved stack, and are fixed in shell 4 by location structure 4c, and making between absorbent assembly 1 and flickering unit 2 to have has suitable gap to form gas channel 3.Expiration enters from gas access 4a, the gas channel 3 that the gap of flowing through between the two in the holes by absorbent assembly 1 and flickering unit 2 in the middle of both forms, then flow out from the 4b of gas outlet through the gap between both and shell.
In the present embodiment, for the base layer that forms flickering unit 2 and the composite construction of scintillator layers, organic scintillator is mixed with to toluene, the solution of the aromatic hydrocarbon such as dimethylbenzene, by this spray solution or be coated in the surface of the polystyrene plastics base layer 2a of forming, in the process of solvent evaporates, solvent is the top layer of slight dissolved polystyrene plastic substrate layer 2a simultaneously also, after volatilizing, solvent solidifies again, therefore and infiltration is distributed in the top layer of base layer 2a and become scintillator layers 2b the organic scintillator molecule, this base layer top layer volatilizes product after being dissolved by the aromatic hydrocarbon solution of organic scintillator, there is good effect as scintillator layers.
Organic scintillator can adopt liquid scintillation technology PPO commonly used, TP, PBD etc., it can be one-component, it can be also the mixture of various ingredients, be called primary scintillator, for the sensitive wave length of make to glimmer light wavelength and photomultiplier tube is complementary, can also add secondary scintillator POPOP etc., found through experiments, the toluene solution of the POPOP that contains 0.5%～5% PPO and 0.005%～0.15% has effect preferably.
In shell 4, the indication component 5 of porose cake (sheet) shape in the middle of also being provided with, indication component 5 also adopts alkaline-resisting polypropylene fiber non-woven fabrics as supporter, flooded the aqueous solution of the phenolphthalein indicator that contains calcium hydroxide and 0.5% on supporter, indication component 5 also is stacked together with flickering unit 2 and fixes by location structure 4c, the expiratory airflow indication component 5 of also can flowing through, thereby indication sampling terminal.
With reference to Fig. 6, when gathering specimen of breath, without the sampling apparatus of the saliva isolator excessive moistening because the experimenter blows out a large amount of salivas often, affect detection efficient, for fear of this phenomenon, connected a saliva isolator 7 on the gas access of sampling apparatus 6, the gas that the experimenter breathes out is by entering sampling apparatus again after saliva isolator 7.
A part and sampling apparatus 6 that saliva isolator 7 can be used as sampling apparatus connect as one, also can be used as one independently disposable product pack in addition, before sampling, again it is connected by the mode of pegging graft with sampling apparatus, after sampling, both are separated, in order to sampling apparatus is inserted in the measuring chamber of gauge.
With reference to Fig. 7 and Fig. 8, the saliva isolator has a cavity 7a, the top of saliva isolator cavity 7a is connected with air inlet pipe 7b, the 7d suitable for reading of saliva isolator escape pipe 7c also is arranged on the top of cavity 7a, when using state, between the bottom of saliva isolator escape pipe residing horizontal plane 7e suitable for reading and cavity 7a, formed a space that holds saliva, be saliva isolator water storage cavity 7f, saliva in expiration is because the effect of gravity flows in water storage cavity 7f, air-flow can flow out from escape pipe 7c by saliva isolator escape pipe 7d suitable for reading, thereby reach the purpose of isolation saliva.
With reference to Fig. 9 and Figure 10, this is another embodiment of saliva isolator, the saliva isolator has cavity 7a and the air inlet pipe 7b be connected at an upper portion thereof, saliva isolator escape pipe 7d suitable for reading extends to the top in cavity 7a from cavity 7a bottom, make to have formed a space that holds saliva between the bottom of escape pipe residing horizontal plane 7e suitable for reading and cavity 7a, be saliva isolator water storage cavity 7f, during sampling, saliva in expiration is because the effect of gravity flows in water storage cavity 7f, air-flow can flow out from escape pipe 7c by saliva isolator escape pipe 7d suitable for reading, thereby reach the purpose of separating most saliva.
With reference to Figure 11, sampling apparatus 6 is inserted in the measuring chamber 8 of suitable scintillation counter, and the measurement result of measurement result and Healthy People is compared, with judgement experimenter's health status.
Based on known principle, in order to reduce background counting rate, scintillation counter is used two coincidence counting techniques that photomultiplier tube is staggered relatively usually, the passage of scintillation light that scintillator produces only has while being received by two photomultiplier tubes simultaneously, the coincidence counting circuit just gives record, therefore, the structural design of sampling apparatus should make the major part flicker luminous energy on scintillator enter the receive window of two photomultiplier tubes by the approach of direct projection, reflection and scattering as far as possible simultaneously.
Claims (11)
1. one kind for medical domain
14c labelling breath test diagnoses the illness, especially for
14the specimen of breath collection of C-urea breath test diagnosing helicobacter pylori infection and the sampling apparatus of measurement, comprise there is gas access, the tubular member of gas outlet and gas channel, and loaded CO in tubular member
2the absorbent assembly of absorbent is characterized in that: also have the flickering unit be oppositely arranged with absorbent assembly, contain solid scintillator in tubular member, the gap between absorbent assembly and flickering unit forms the part of gas channel or gas channel.
2. sampling apparatus according to claim 1, it is characterized in that: flickering unit is the shaped component of plastic scintillant.
3. sampling apparatus according to claim 1, it is characterized in that: flickering unit is the base layer of printing opacity or leaded light and the composite construction of scintillator layers.
4. sampling apparatus according to claim 3 is characterized in that: described scintillator layers is coating or or the coating of plastic scintillant molten mass of plastic scintillant lysate.
5. sampling apparatus according to claim 3, it is characterized in that: the base layer of described flickering unit is the polystyrene plastics shaped component, scintillator layers is the product that volatilizes after polystyrene plastics base layer top layer is dissolved by the aromatic hydrocarbon solution of organic scintillator.
6. sampling apparatus according to claim 5, it is characterized in that: the aromatic hydrocarbon solution of described organic scintillator is to contain the toluene solution that concentration is 0.5%～8%PPO.
7. sampling apparatus according to claim 6, it is characterized in that: the aromatic hydrocarbon solution of organic scintillator has also comprised 0.005%～0.15% POPOP.
8. according to claim 1 or 2 or 3 or 4 or 5 or 6 or 7 described sampling apparatuses, it is characterized in that: also have an indication component that is used to indicate the sampling terminal on the gas channel in tubular member, loaded alkali and acid-base indicator on this indication component.
9. according to claim 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 described sampling apparatuses, it is characterized in that: the gas access of described sampling apparatus also is connected with a saliva isolator.
10. sampling apparatus according to claim 9, it is characterized in that: described saliva isolator has saliva isolator cavity and is connected with air inlet pipe and escape pipe, the escape pipe top that is positioned at cavity suitable for reading, during in using state, form a water storage cavity when the saliva isolator between escape pipe residing horizontal plane suitable for reading and cavity bottom.
11. one kind for
14c labelling breath test diagnoses the illness, especially for
14the using method of the expiration sampling apparatus of C-urea breath test diagnosing helicobacter pylori infection, except allowing the experimenter take
14outside the medicine of C labelling, also comprise following process:
One, the experimenter exhales to the gas access of sampling apparatus of the present invention, this sampling apparatus comprises a tubular member with gas access, gas outlet and gas channel, also comprise absorbent assembly and the flickering unit that contains solid scintillator in cast structure member, gap between absorbent assembly and flickering unit forms the part of gas channel or gas channel, also be provided with an indication component that is used to refer to the sampling terminal in gas channel, the part that the saliva isolator can be used as sampling apparatus is connected on its gas access.
Two, observe the change color of indication component.
Three, reach home after color and stop exhaling.
If be connected with independently the saliva isolator on four sampling apparatuses both separated.
Five, sampling apparatus is inserted in the measuring chamber of scintillation counter, in sample
14the beta-particle that the C decay produces strikes the flickering unit corresponding with absorbent assembly, and the scintillator on flickering unit is excited, can be by the passage of scintillation light of the photomultiplier tube of scintillation counter record thereby produce.
Six, the measurement data of measurement result and Healthy People is compared.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201310023027 CN103142232A (en) | 2013-01-11 | 2013-01-11 | Expiration sampling device and application method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201310023027 CN103142232A (en) | 2013-01-11 | 2013-01-11 | Expiration sampling device and application method thereof |
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|---|---|
| CN103142232A true CN103142232A (en) | 2013-06-12 |
Family
ID=48540783
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| CN 201310023027 Pending CN103142232A (en) | 2013-01-11 | 2013-01-11 | Expiration sampling device and application method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103920381A (en) * | 2013-09-30 | 2014-07-16 | 安徽养和医疗器械设备有限公司 | Carbon dioxide absorbent |
| CN104931999A (en) * | 2015-03-27 | 2015-09-23 | 安徽养和医疗器械设备有限公司 | Solid scintillation vial |
| CN109342482A (en) * | 2018-11-16 | 2019-02-15 | 深圳市福瑞康科技有限公司 | A kind of flicker detection method, device, X-ray excited polycrystalline structure scintillator and sample collecting apparatus |
| CN109557121A (en) * | 2018-12-12 | 2019-04-02 | 深圳市福瑞康科技有限公司 | A kind of detection module and detection device |
| CN109655478A (en) * | 2018-12-12 | 2019-04-19 | 深圳市福瑞康科技有限公司 | A kind of flash detecting device |
| CN110689775A (en) * | 2019-10-17 | 2020-01-14 | 山西科林矿山检测技术有限责任公司 | Compressed oxygen self-rescuer simulation drilling teaching instrument |
| CN111722262A (en) * | 2020-06-28 | 2020-09-29 | 安徽养和医疗器械设备有限公司 | Scintillation absorption liquid |
-
2013
- 2013-01-11 CN CN 201310023027 patent/CN103142232A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103920381A (en) * | 2013-09-30 | 2014-07-16 | 安徽养和医疗器械设备有限公司 | Carbon dioxide absorbent |
| CN104931999A (en) * | 2015-03-27 | 2015-09-23 | 安徽养和医疗器械设备有限公司 | Solid scintillation vial |
| CN109342482A (en) * | 2018-11-16 | 2019-02-15 | 深圳市福瑞康科技有限公司 | A kind of flicker detection method, device, X-ray excited polycrystalline structure scintillator and sample collecting apparatus |
| CN109342482B (en) * | 2018-11-16 | 2024-05-28 | 深圳市福瑞康科技有限公司 | Scintillation detection device and method and application thereof |
| CN109557121A (en) * | 2018-12-12 | 2019-04-02 | 深圳市福瑞康科技有限公司 | A kind of detection module and detection device |
| CN109655478A (en) * | 2018-12-12 | 2019-04-19 | 深圳市福瑞康科技有限公司 | A kind of flash detecting device |
| CN109655478B (en) * | 2018-12-12 | 2024-02-27 | 深圳市福瑞康科技有限公司 | Scintillation detection device |
| CN109557121B (en) * | 2018-12-12 | 2024-02-27 | 深圳市福瑞康科技有限公司 | Detection module and detection equipment |
| CN110689775A (en) * | 2019-10-17 | 2020-01-14 | 山西科林矿山检测技术有限责任公司 | Compressed oxygen self-rescuer simulation drilling teaching instrument |
| CN111722262A (en) * | 2020-06-28 | 2020-09-29 | 安徽养和医疗器械设备有限公司 | Scintillation absorption liquid |
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Application publication date: 20130612 |