CN2525518Y - 14CO2 gas sampler - Google Patents
14CO2 gas sampler Download PDFInfo
- Publication number
- CN2525518Y CN2525518Y CN 02207235 CN02207235U CN2525518Y CN 2525518 Y CN2525518 Y CN 2525518Y CN 02207235 CN02207235 CN 02207235 CN 02207235 U CN02207235 U CN 02207235U CN 2525518 Y CN2525518 Y CN 2525518Y
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- cavity
- absorbent assembly
- sampling apparatus
- sampling
- window
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Abstract
The utility model relates to a sampler used for collecting the carbon dioxide gas sample marked <14>C. The sampler is suitable for the collection of the breath test sample of the compound marked <14>C and is used to diagnose the disease in the medical science, such as the collection and the measurement of the sample infected by the helicobacter pylori of the diagnosis of the breath test of <14>C-carbamide. The sampler comprises a cavity provided with an opening through which the gas is allowed to pass and an absorbing assembly loaded with the carbon dioxide absorbefacient. The absorbing assembly is fixed inside the cavity. The cavity is provided with a window which can expose the absorbing assembly on the probe head of the measuring apparatus. The exterior of the cavity is also provided with a surface or an edge or an arris or a salience or a groove, which adapts to the structure of the inner surface of the apparatus.
Description
Affiliated technical field
The utility model relates to a kind of
14C mark carbon dioxide (
14CO
2) gas sampling assembly, be applicable to medically
14Sample collection and measurement that C tagged compound breath test diagnoses the illness, particularly
14The sample collection and the analysis of C-urea breath test diagnosing helicobacter pylori infection.
Background technology
Breath test is usually used in the diagnosis of some disease, when give the person under inspection a certain amount of certain
14Behind the C tagged compound, owing to the reason of disease can cause the change of metabolism, it one of changes is the metabolic product of discharging via exhaling
14The C-carbon dioxide (
14CO
2) amount can there are differences the CO that gather to breathe out
2Gas is measured wherein
14CO
2Content, whether diagnosable disease exists and degree.For example, it is oral to be subjected to the patient of helicobacter pylori infections
14During C-urea, produce in human body non-existent urease originally because one of feature of helicobacter pylori is it, urease can with
14The C-urea decomposition produces
14CO
2,
14CO
2Excrete from expiration, gather patient expired CO
2Gas also detects wherein
14CO
2Content, will be higher than not infection population far away, this is because the infected is not oral
14Behind the C-urea,
14C-urea will be discharged from urine with prototype, rather than discharge from exhale the back that is decomposed
14CO
2
For
14CO
2The collection of gas sample and analysis, existent method comprises: 1, gas feeds one by a pipeline and contains CO
2In the container of absorbing agent; 2, gas feeds a pipeline that is placed with absorbent assembly, and absorbent assembly is porosint loading CO such as filter paper
2Absorbing agent.The sample of gathering carries out activity analysis with scintillation counter or Geiger one Miller calculating instrument.
Chinese invention patent application 96193244 discloses a kind of sampling apparatus, and this device is installed in an absorbent assembly temporarily is used for sampling on the tubular member, after the sampling absorbent assembly is pulled down and measures.Chinese invention patent application 97180427 discloses another kind of device, the absorbent assembly of this device is to be fixed on the tubular member, the film assembly that a low β ray capture rate is arranged on the sampling apparatus, after sampling finishes, whole device can be placed on the instrument and measure, when measuring, above-mentioned film assembly is between the measuring sonde of absorbent assembly and instrument, in order to avoid measurement mechanism is by radioactive contamination.
Above-mentioned two kinds of devices all have shortcoming, and the former measures after absorbent assembly need being pulled down, and use inconvenience.The latter has a film assembly between absorbent assembly and measuring sonde, though this film assembly has adopted low-density made and very thin,
14The β ray energy of C is very low, and the small obstruct before arriving measuring sonde also can reduce detection efficiency greatly.
Design content
The purpose of this utility model is to provide a kind of more effective sampling apparatus, this device is applicable to that breath test diagnoses the illness clinically, can carry out sample collection easily and directly sampling apparatus is put into instrument and measure, have higher detection efficiency again, make measurement result more accurate and true.
Technical solution of the present utility model is: will be loaded with CO
2The absorbent assembly of absorbing agent is fixed on an inside cavity, there is an opening to be used for incoming call gas on the cavity, other has one or more opening as gas vent, when expiration enters cavity and when outlet is flowed out, flow through or pass through absorbent assembly, for absorbent assembly being exposed to the measuring sonde of instrument, on cavity, has a opening at least as window, this window partly or entirely is exposed to absorbent assembly the measuring sonde of instrument when measuring, like this, the β ray that emits from absorbent assembly can arrive measuring sonde without any additional barriers ground.
Measure in order easily sampling apparatus to be put into instrumentation, the cavity outside has surface, limit, rib, projection or the groove that adapts with the instrument injection port, insert the injection port of instrument when sampling apparatus after, the residing position of sampling apparatus is predefined, it is the measuring sonde that window on the sampling apparatus is just aimed at instrument, and there is certain safe distance between absorbent assembly and the measuring sonde, avoids wiping and bump or pollute probe.
Can window be set on window, window just is opened when being necessary.
Absorbent assembly is as the stilt CO absorption with porosint or shaggy material
2Absorbing agent forms, when expiration is passed through or pass through absorbent assembly, and CO
2Be adsorbed on it.CO
2Absorbing agent is based on physics or the principles of chemistry absorb CO
2Any material, the most frequently used is various single alkali compounds or their potpourri, wherein best is alkali metal hydroxide, as calcium hydroxide, NaOH, lithium hydroxide and composition thereof, and organic amine compound.
CO commonly used
2Often be solid state after the absorbing agent drying, split away off from stilt for fear of it and pollute, preferably use retention agent, as at CO
2Adding bonding agent in the absorbing agent is bonded in it on stilt, or in absorbing agent, add surfactant, high boiling organic solvent, organic amine compound, as surfactant 6501, glycerine, monoethanolamine etc., make absorbent assembly keep certain moistening degree, thereby make CO
2Absorbing agent is difficult to split away off from stilt.
On absorbent assembly, can also load the indicator that is used to indicate the sampling terminal point, at basic Co
2Common acid neutralization indicator in the absorbing agent, its metachromasia can determine suitable sampling quantity.
An independent indication component that is specifically designed to indication sampling terminal point also can be set, load appropriate C O on this independent indication component in addition
2Absorbing agent and indicator.If cavity material is nontransparent, then transparent window is set, so that observe the sampling terminal point in corresponding position.
That the acid base indicator that can adopt comprises is phenol red, phenolphthalein, thymolphthalein, trinitro-toluene, tropaeolin, curcumin etc. and their potpourri.
Description of drawings
Figure one, figure two are the structural map of first embodiment of the present utility model, and wherein figure two is the A-A section of figure one, and figure three is the synoptic diagram after window is opened.
Figure four, figure five are the structural map of second embodiment of the present utility model, and wherein figure five is the B-B sectional view of figure four, and figure six is synoptic diagram that window is opened.
Figure seven is synoptic diagram of the 3rd embodiment of the present utility model.
Figure eight is after sampling apparatus is inserted into the instrumentation socket, the synoptic diagram when being in the measuring position.
In the accompanying drawing, (1) be cavity, (2) are the gas inlet ports, and (3) are gas vents, (4) be absorbent assembly, (5) be window, (6) are windows, and (7) are the insertion mouth inner surface structures on the instrument, (8) be the outer surface structure of sampling apparatus, (9) be the measuring sonde of instrument, (10) are view windows, and (11) are the independent indication components that is used to indicate the sampling terminal point.
Specific embodiment
In first specific embodiment of the present utility model, absorbent assembly (4) is fixed in the cavity (1), and cavity (1) is made by plastics with suitable rigidity or cardboard.Absorbent assembly (4) uses the expanded material polyurethane sponge of porous as stilt, NaOH is formulated into the water of 2mol/L and the mixed solution of glycerine [glycerine: water=2: 8 (volume ratio)], add the thymolphthalein that accounts for weight about 0.3% in the above-mentioned solution in addition, evenly spray the above-mentioned solution of 1ml on the stilt effective surface of each absorbent assembly.Window (6) is transparent plastics or glass plate-like material, and thickness is unrestricted, and the size of its size and window (5) is complementary, and window (6) is stuck in or is bonded at and makes window (5) airtight on the cavity (1).During sampling, exhaling enters by inlet (2), and the absorbent assembly of flowing through (4) back is from outlet (3) effusion, contained CO in the expiration
2The NaOH that is absorbed on the assembly (4) absorbs, along with CO
2The increase of uptake, indicator will produce metachromasia, sees through window (6) and can observe the sampling terminal point.After sampling is finished, window (6) is opened, be inserted into the sample introduction socket of instrumentation when sampling apparatus after, window (5) is aimed at the measuring sonde (9) of instrument, on the absorbent assembly (4)
14The C soft beta ray can arrive the measuring sonde (9) of instrument under the situation of no any additional barriers, detection efficiency is compared with the situation that has the thin film assembly to be separated by, and exceeds more than 10%.
In second specific embodiment of the present utility model, window (6) is the plate that a size is slightly larger than window (5), and window (6) is bonded in cavity (1) by coating adhesive sticker bonding agent and upward covers window (5).The stilt of absorbent assembly (4) is a non-woven fibre cloth, and the methanol solution that 1ml is contained NaOH 1mol/L and monoethanolamine 2mol/L is sprayed on the stilt effective surface of each absorbent assembly, and vacuum volatilizes methyl alcohol.In cavity (1) inside, be provided with an independently terminal point indication component (11) in addition, this independent indication component also uses non-woven fibre cloth to make stilt, be loaded with a certain amount of CaOH saturated aqueous solution on the stilt, also contain the phenolphthalein indicator about 0.5% in the solution, when expiratory flow through absorbent assembly (4) time, the independent indication component (11) of also will flowing through, the CaOH on the indication component absorbs CO
2The back generates CaCO
3, become colorless from redness as the phenolphthalein of PH indicator, with prompting sampling terminal point.When cavity (1) when making of non-transparent material, the position corresponding at independent indication component (11) is provided with a transparent view window (10), so that observe the sampling terminal point.
With reference to figure seven, in embodiment three, the gas vent (3) on the cavity (1) is same opening with window (5), exhales and flows out from window (5) by absorbent assembly (4) after air intake opening (2) enters cavity.Absorbent assembly (4) is to be bonded in as stilt on the inside surface of cavity with the cloth with appropriate well crack rate, loads the saturated aqueous solution of CaOH on the stilt, also contains 0.4% phenol red indicator in the solution.In the present embodiment, being provided with of window is optional, if window is set, then window must be opened before sampling in advance.
With reference to figure eight, a sampling apparatus is inserted into the measurement socket of instrumentation, bulge-structure on the sampling apparatus (8) just matches with groove structure (7) on the instrument, sampling apparatus can only enter the apparatus measures mouth along intrinsic orbital motion, after sampling apparatus inserts and puts in place, window (5) is just aimed at the measuring sonde (9) of instrument, and has certain safe distance between probe (9) and the absorbent assembly (4).
Claims (12)
1, a kind of being used for gathers
14CO
2The sampling apparatus of gas sample comprises absorbent assembly and the cavity with gas import and export, and absorbent assembly is permanently affixed at inside cavity, it is characterized in that: cavity is provided with absorbent assembly partly or entirely is exposed to the outer window of cavity.
2, sampling apparatus according to claim 1 is characterized in that: having can be with close and the window of opening.
3, sampling apparatus according to claim 2 is characterized in that: window is by being stuck in or being bonded on the cavity and with the platy structure of close.
4, according to claim 1 or 2 or 3 described sampling apparatuses, it is characterized in that: have the surface or limit or rib or projection or the groove that adapt with the instrument inner surface structure in the outside of cavity.
5, according to claim 1 or 2 or 3 or 4 described sampling apparatuses, it is characterized in that: absorbent assembly is to have loaded basic Co on porosint or the shaggy material
2Absorbing agent.
6, sampling apparatus according to claim 5 is characterized in that: alkali compounds is alkali metal hydroxide or organic amine compound or their potpourri.
7, according to claim 5 or 6 described sampling apparatuses, it is characterized in that: loaded retention agent on the absorbent assembly.
8, sampling apparatus according to claim 7 is characterized in that: retention agent is bonding agent or surfactant or high boiling organic solvent or organic amine compound or the potpourri of component arbitrarily in them.
9, according to the described sampling apparatus of claim 1-8, it is characterized in that: loaded the PH indicator that is used to observe the sampling terminal point on the absorbent assembly.
10, according to the described sampling apparatus of claim 1-8, it is characterized in that: be provided with the independent indication component that is used to indicate the sampling terminal point in the cavity.
11, sampling apparatus according to claim 10 is characterized in that: independent indication component is to be loaded with CO on the stilt of porosint
2Absorbing agent and PH indicator.
12, according to claim 9 or 11 described sampling apparatuses, it is characterized in that: the PH indicator is phenolphthalein or thymolphthalein or phenol red or trinitro-toluene or tropaeolin or curcumin or the potpourri of component arbitrarily in them.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02207235 CN2525518Y (en) | 2002-03-06 | 2002-03-06 | 14CO2 gas sampler |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02207235 CN2525518Y (en) | 2002-03-06 | 2002-03-06 | 14CO2 gas sampler |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2525518Y true CN2525518Y (en) | 2002-12-11 |
Family
ID=33688297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02207235 Expired - Lifetime CN2525518Y (en) | 2002-03-06 | 2002-03-06 | 14CO2 gas sampler |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2525518Y (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102338708A (en) * | 2010-07-26 | 2012-02-01 | 深圳市中核海得威生物科技有限公司 | Bag for sampling gas used for breath test |
| CN102921273A (en) * | 2012-11-05 | 2013-02-13 | 中国船舶重工集团公司第七一八研究所 | Mine carbon dioxide absorbent and preparation method thereof |
| CN103926240A (en) * | 2013-09-30 | 2014-07-16 | 安徽养和医疗器械设备有限公司 | Carbon dioxide absorption indicator |
| CN104049077A (en) * | 2014-06-27 | 2014-09-17 | 安徽养和医疗器械设备有限公司 | Helicobacter pylori detector |
| CN104931999A (en) * | 2015-03-27 | 2015-09-23 | 安徽养和医疗器械设备有限公司 | Solid scintillation vial |
| CN105455815A (en) * | 2016-01-05 | 2016-04-06 | 广州医科大学附属第一医院 | Airway pH value measuring system |
| CN106264623A (en) * | 2016-11-04 | 2017-01-04 | 天益健康科学研究院（镇江）有限公司 | A kind of vagina sampling pen |
| CN108508475A (en) * | 2018-01-24 | 2018-09-07 | 中国原子能科学研究院 | C-14 high-sensitivity measurement devices based on gas sampling positive ion source |
| CN109540610A (en) * | 2018-12-12 | 2019-03-29 | 深圳市福瑞康科技有限公司 | A kind of sample collecting apparatus |
| CN110044890A (en) * | 2019-04-27 | 2019-07-23 | 谱尼测试集团北京科学技术研究院有限公司 | A kind of helicobacter pylori quick screening method |
| CN111044547A (en) * | 2019-12-31 | 2020-04-21 | 深圳市福瑞康科技有限公司 | Absorber, gas collecting card, respiration detection equipment, preparation method and application |
-
2002
- 2002-03-06 CN CN 02207235 patent/CN2525518Y/en not_active Expired - Lifetime
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102338708A (en) * | 2010-07-26 | 2012-02-01 | 深圳市中核海得威生物科技有限公司 | Bag for sampling gas used for breath test |
| CN102338708B (en) * | 2010-07-26 | 2013-04-24 | 深圳市中核海得威生物科技有限公司 | Bag for sampling gas used for breath test |
| CN102921273A (en) * | 2012-11-05 | 2013-02-13 | 中国船舶重工集团公司第七一八研究所 | Mine carbon dioxide absorbent and preparation method thereof |
| CN103926240A (en) * | 2013-09-30 | 2014-07-16 | 安徽养和医疗器械设备有限公司 | Carbon dioxide absorption indicator |
| CN104049077A (en) * | 2014-06-27 | 2014-09-17 | 安徽养和医疗器械设备有限公司 | Helicobacter pylori detector |
| CN104931999A (en) * | 2015-03-27 | 2015-09-23 | 安徽养和医疗器械设备有限公司 | Solid scintillation vial |
| CN105455815A (en) * | 2016-01-05 | 2016-04-06 | 广州医科大学附属第一医院 | Airway pH value measuring system |
| CN106264623A (en) * | 2016-11-04 | 2017-01-04 | 天益健康科学研究院（镇江）有限公司 | A kind of vagina sampling pen |
| CN108508475A (en) * | 2018-01-24 | 2018-09-07 | 中国原子能科学研究院 | C-14 high-sensitivity measurement devices based on gas sampling positive ion source |
| CN109540610A (en) * | 2018-12-12 | 2019-03-29 | 深圳市福瑞康科技有限公司 | A kind of sample collecting apparatus |
| CN109540610B (en) * | 2018-12-12 | 2024-01-30 | 深圳市福瑞康科技有限公司 | Sample collection device |
| CN110044890A (en) * | 2019-04-27 | 2019-07-23 | 谱尼测试集团北京科学技术研究院有限公司 | A kind of helicobacter pylori quick screening method |
| CN111044547A (en) * | 2019-12-31 | 2020-04-21 | 深圳市福瑞康科技有限公司 | Absorber, gas collecting card, respiration detection equipment, preparation method and application |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: ANHUI YANGHE AND MEDICAL EQUIPMENT CO., LTD. Free format text: FORMER OWNER: YANGYIHE BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD., SHANGHAI Effective date: 20051125 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20051125 Address after: 231400 No. 8 Xiang Bei Road, Tongcheng Private Economic Development Zone, Anhui, China Patentee after: Anhui Young-Hearty Medical Appliance & Equipment Co., Ltd. Address before: 201108 No. 528 East Spring Road, Xhenzhuang Industrial Zone, Shanghai, Minhang District Patentee before: Yangyihe Biological Science and Technology Co., Ltd., Shanghai |
|
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20120306 Granted publication date: 20021211 |