CN203539487U - Whole animal body exposure room - Google Patents
Whole animal body exposure room Download PDFInfo
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- CN203539487U CN203539487U CN201320492645.2U CN201320492645U CN203539487U CN 203539487 U CN203539487 U CN 203539487U CN 201320492645 U CN201320492645 U CN 201320492645U CN 203539487 U CN203539487 U CN 203539487U
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Abstract
The utility model provides a whole animal body exposure room which comprises a whole body exposure room for placing an animal for an inhalation toxicity experiment, an aerosol generating system communicated with the whole body exposure room and used for generating aerosol for the inhalation toxicity experiment, a sampling system for acquiring the concentration of the aerosol in the whole body exposure room, a waste gas recovery and treatment system communicated with the whole body exposure room and used for recovering and treating waste gas produced by the animal and redundant aerosol, and a control system for adjusting the concentration of the aerosol in the whole body exposure room in the experiment process. The concentration of the aerosol in the whole body exposure room is detected through the control system and the sampling system, automatic control of the whole animal body exposure room is achieved, the concentration of the aerosol in the whole body exposure room is accurate in control and meets the experiment requirement. The whole animal body exposure room is provided with the automatic control system and is high in automation degree and experiment accuracy.
Description
Technical field
This utility model relates to animal and sucks toxicological experiment field, particularly relates to a kind of animal systemic exposure system.Can be used for sucking the evaluation of toxicity drug safety, pesticide acute toxicity and suck experimentation, the various diseases model that builds animal and its curative effect of medication experimentation, atmosphere pollution to the research of animal breath systematic influence etc.
Background technology
Inhalation toxicology be research can inhalation (inhalatio) to body toxic action occur, development and the various conditions of eliminating, rule and mechanism and to can inhalation (inhalatio) carrying out a science of hazard assessment.Its professional research contents mainly contains: the physicochemical property of various materials in air; The fundamental biological knowledge of respiratory tract; Deposition in vivo of inhalation (inhalatio) and delay and and body in interaction between important system, organ; These interactions are how to cause disease to produce.
Along with international inhalation toxicology research is increasingly active, lot of domestic experts has also been fully recognized that the significance of inhalation toxicology.Many experts have introduced some concepts of inhalation toxicology, method and progress as Jiang Quanguan, Chen Bingheng, Lv Baiqin etc. in monograph.The toxicity of pesticide experimental technique that Ministry of Public Health is worked out, disinfectant toxicity grading standard etc. all have method and the Introduction on Standard of some inhalation toxicologys.Our research field, content and method, covered the various aspects that inhalation toxicology is studied substantially.The research level in some field even reaches or has approached international most advanced level.Object from research, has couple crowd's investigation, also has pair animal to comprise the research of rat, mice, rabbit, hamster etc.; Equipment from research, all adopts exposure in static total enclosure chamber; From the method for research, have and adopt epidemiological method, there is application poison for dynamic method, utilize ultrasonic diagnosis technology, coordination poison labelling method, radioaerosol pulmonary ventilation imaging technology, fluorescent antibody technique etc.; The longest contamination time has continuous contamination 8 hours, also has and carries out Epidemiological study to contacting 5 years above crowds; Have and carry out the experiment of whole animal lung lavage, also have and carry out isolated bronchia bronchoalveolar lavage fluid analysis; The kind of research poisonous substance more reaches and comprises more than tens kinds such as chlorine, desert dirt, unsymmetric dimethyl hydrazine, Diesel Exhaust, Vehicle Exhaust Particulate; The index of analyzing has that the enzyme histochemistry of rat olfactory sensation mucosa toxicity changes, tens kinds of variation, spleen NK cell and K cell, hepatomicrosome calcium pump, the platelet etc. of various enzymes in lung-douching fluid.
In existing inhalation toxicology research, the equipment of research is mainly exposure in static total enclosure chamber, and quiet formula Inhalation is a kind of contamination method that carries out toxicity on inhalation experiment.Laboratory animal is put into the airtight good toxicant exposure cabinet with gas stirring device, and disposable input gaseous state tested material or volatile liquid, make tested material in the interior air of cabinet reach desired concn, after the contamination of certain hour, opens toxicant exposure cabinet and take out animal.Exposure in static total enclosure chamber equipment is simpler, and the amount that consumes tested material is less, but concentration is wayward constant, and, be subject to the restriction of toxicant exposure cabinet volume, therefore be used for the short time Inhalation of toy.
Existing exposure in static total enclosure chamber, concentration in toxicant exposure chamber is wayward, contamination time is short, and animal is breathed out or the gas got rid of can impact contamination material, finally affects experimental result.
Utility model content
The object of this utility model embodiment is to provide a kind of animal systemic exposure system, solved existing exposure in static total enclosure chamber, concentration in toxicant exposure chamber is wayward, contamination time is short, and animal is breathed out or the gas got rid of can impact contamination material, finally affects the technical problem of experimental result.
To achieve these goals, this utility model provides a kind of animal systemic exposure system, wherein, comprising:
Systemic exposure chamber, sucks for placing the animal that toxicological experiment is used;
Aerosol generation systems, is communicated with the aerosol of using for generating described suction toxicological experiment with described systemic exposure chamber;
Sampling system, for gathering the indoor aerocolloidal concentration of described systemic exposure;
Waste gas reclamation treatment system, is communicated with described systemic exposure chamber, for the waste gas of described animal generation and unnecessary described aerosol are reclaimed and processed;
Control system, for controlling the indoor described aerocolloidal concentration of described systemic exposure.
Preferably, described aerosol generation systems comprise air compressor for air is provided, aerosol generator, for regulating the first air flow controller of the air inlet amount of described aerosol generator, for the medicinal liquid bottle of medicinal liquid is provided to described aerosol generator, for regulating the peristaltic pump of the amount of liquid medicine that enters into described aerosol generator, export with the aerosol of described aerosol generator the aerosol diluter that is connected and for regulating the second air flow controller of the air inlet amount of described aerosol diluter; Described aerosol diluter is connected with the aerosol import that the first end of described systemic exposure chamber arranges.
Preferably, on described systemic exposure chamber, be provided with pressure transducer, humidity sensor, temperature sensor and oxygen concentration sensor and sampling of aerosol mouth.
Preferably, described waste gas reclamation treatment system comprises in turn connected waste gas recovery cylinder, filter, exhaust gas flow controller, valve, vacuum pump and high altitude discharge processing system; Described waste gas recovery cylinder is connected with the waste gas outlet of the second end setting of described systemic exposure chamber.
Preferably, described sampling system comprises two-position two-way solenoid valve, aerosol concentration monitor and aerosol flow controller and the vacuum pump being connected successively.
Preferably, described control system comprises industrial PC, touch screen computer, software programming control terminal, data collecting card, Control plate, catalyst and RS485 communication interface; On described data collecting card, connect described industrial PC, under connect described Control plate, described Control plate connects described catalyst, described catalyst is for controlling the switching of described vacuum pump and described air compressor; Described data collecting card is for gathering the indoor pressure of described systemic exposure, humidity, temperature and oxygen concentration; Described software programming control terminal is for coding and send the corresponding command; Described RS485 communication interface is connecting described industrial PC.
Preferably, also comprise the micro-negative pressure processing system of security mask cabinet and vacuum; Described security mask cabinet is used for installing described systemic exposure chamber, described aerosol generation systems, described sampling system, described waste gas reclamation treatment system and described control system and the micro-negative pressure processing system of described vacuum, and the micro-negative pressure processing system of described vacuum is for preventing that the aerosol of the leakage in described security mask cabinet from entering atmosphere.
Preferably, described systemic exposure chamber comprises the conical cavity of the conical cavity of interlude circular cylindrical cavity and upper end and lower end; Described systemic exposure is indoor is provided with the atomization bubbler being connected with the aerosol import of the first end setting of described systemic exposure chamber;
On the cavity wall of described interlude circular cylindrical cavity, be provided with described pressure transducer, described humidity sensor, described temperature sensor and described oxygen concentration sensor and described sampling of aerosol mouth.
Preferably, described systemic exposure chamber also comprises the animal wastes collecting processing system that is arranged on bottom, is connected with the Waste outlet of the bottom of the conical cavity in described lower end.
Preferably, on the cavity wall in the same level of the conical cavity in described lower end, be evenly provided with three waste gas outlets.
Preferably, described animal wastes collecting processing system comprises collecting dung case and Waste Water Treatment; Described collecting dung case is connected with described Waste outlet, and the bottom of described collecting dung case is provided with drainage screen; In described collecting dung case, there is feces preliminary treatment material.
Preferably, described systemic exposure chamber also comprises purging system, for the systemic exposure chamber after washing test.
Preferably, described purging system comprises the cleaning shower nozzle that cleanout fluid stores conveyer device, the first cleaning valve switch, the second cleaning valve switch, the washer jet being connected with described the first cleaning valve switch and is connected with described the second cleaning valve switch; Described washer jet is a plurality of, is distributed on the top of described interlude circular cylindrical cavity.
Preferably, indoor the second ultraviolet disinfection lamp, the second illuminating lamp and the animal behavior remote monitoring photographic head of being provided with of described systemic exposure.
At least there is following technique effect in this utility model embodiment:
1) by control system and sampling system are set, the indoor aerosol concentration of systemic exposure is detected, realize the automatic control of animal systemic exposure system, and the indoor aerosol concentration of systemic exposure controls accurately, meet the requirement of experiment.Have automation control system, automaticity is high, and experimental precision is high.Aerosol is in the indoor dynamic flow of systemic exposure, waste gas reclamation treatment system is for reclaiming the waste gas of described animal generation and unnecessary described aerosol and process, prevent that animal from breathing out or the gas of eliminating can impact aerosol, solved existing exposure in static total enclosure chamber, concentration in toxicant exposure chamber is wayward, contamination time is short, animal is breathed out or the gas of eliminating can impact contamination material, finally affects the technical problem of experimental result.
2) by aerosol generation systems is set, obtain the aerosol of suitable concn, to meet the requirement of experiment.
3) by the micro-negative pressure processing system of vacuum is set, for preventing that the aerosol of the leakage in security mask cabinet from entering atmosphere, to environment or to laboratory technician's health, impact.
4) systemic exposure chamber comprises the conical cavity of the conical cavity of interlude circular cylindrical cavity and upper end and lower end, adopts the exposure chamber cavity of this structure, inner aerocolloidal being more evenly distributed, and volume meets internationalization experimental standard more.On the cavity wall of the conical cavity in lower end, be provided with three waste gas outlets, be distributed in the same level on cavity wall, this kind is provided with that to be beneficial to the indoor aerosol concentration of systemic exposure stable, prevent that more existing aerofluxus scheme or 2 aerofluxus schemes from causing systemic exposure chamber interior aerosol because the mobile aerocolloidal concentration of inside that causes of reason of pressure reduction is unstable, is unfavorable for the carrying out of experiment.
5) because animal is in the process of experiment, discharge feces possibly, urinate or other material, for the impact on aerosol component of the garbage that prevents the discharge of animal in exposure chamber, also prevent that garbage from impacting animal behavior, also for follow-up easy to clean, animal wastes collecting processing system is set.Also be provided with purging system, for the systemic exposure chamber after washing test simultaneously.
According to the detailed description to this utility model specific embodiment by reference to the accompanying drawings below, those skilled in the art will understand above-mentioned and other objects, advantage and feature of the present utility model more.
Accompanying drawing explanation
Hereinafter in exemplary and nonrestrictive mode, describe specific embodiments more of the present utility model in detail with reference to the accompanying drawings.In accompanying drawing, identical Reference numeral has indicated same or similar parts or part.It should be appreciated by those skilled in the art that these accompanying drawings may not draw in proportion.In accompanying drawing:
Fig. 1 is the system diagram of the animal systemic exposure system that provides of this utility model embodiment.
The specific embodiment
For making object, technical scheme and the advantage of this utility model embodiment clearer, below in conjunction with accompanying drawing, specific embodiment is described in detail.
As shown in Figure 1, a kind of animal systemic exposure system, comprising:
Systemic exposure chamber, sucks for placing the animal that toxicological experiment is used;
Aerosol generation systems, is communicated with systemic exposure chamber, for generating, sucks the aerosol that toxicological experiment is used;
Sampling system, for gathering the indoor aerocolloidal concentration of systemic exposure;
Waste gas reclamation treatment system, is communicated with systemic exposure chamber, for waste gas and the unnecessary aerosol that animal is produced, reclaims and processes;
Control system, for controlling the indoor aerocolloidal concentration of systemic exposure in systemic exposure indoor aerocolloidal concentration, especially regulating and controlling experimentation.
By control system and sampling system are set, the indoor aerosol concentration of systemic exposure is detected, realize the automatic control of animal systemic exposure system, and the indoor aerosol concentration of systemic exposure controls accurately, meet the requirement of experiment.Have automation control system, automaticity is high, and experimental precision is high.Aerosol is in the indoor dynamic flow of systemic exposure, waste gas reclamation treatment system is for reclaiming the waste gas of described animal generation and unnecessary described aerosol and process, prevent that animal from breathing out or the gas of eliminating can impact aerosol, solved existing exposure in static total enclosure chamber, concentration in toxicant exposure chamber is wayward, contamination time is short, animal is breathed out or the gas of eliminating can impact contamination material, finally affects the technical problem of experimental result.
In another one embodiment of the present utility model, as shown in Figure 1, aerosol generation systems comprises: air compressor 111, for the air of compression drying cleaning is provided; Aerosol generator 11, for generation of the aerosol of high concentration; The first air flow controller 17, for regulating the air inlet amount of aerosol generator 11; Medicinal liquid bottle 13, for providing medicinal liquid to aerosol generator 11; Peristaltic pump 15, for regulating the medicinal liquid of medicinal liquid bottle 13 to enter into the amount of liquid medicine of aerosol generator 11; Export with the aerosol of aerosol generator 11 aerosol diluter 12 being connected, for the high concentration aerosol that aerosol generator 11 is produced, be diluted to the needed concentration of experiment; The second air flow controller 16, for regulating the air inlet amount of aerosol diluter 12.In the exit of air compressor 111, be provided with air flow control valve 19, at the front end of air flow control valve 19, be provided with device for drying and filtering; Aerosol diluter 12 is connected with the aerosol import that the first end of systemic exposure chamber arranges; The waste gas outlet 90 that the second end of systemic exposure chamber arranges is connected with waste gas reclamation treatment system, and the waste gas that the animal in systemic exposure chamber produces and unnecessary aerosol are reclaimed and process by waste gas reclamation treatment system.
In visible this utility model embodiment, the first via air that air compressor 111 produces enters into aerosol generator 11, medicinal liquid enters into aerosol generator 11 from medicinal liquid bottle 13, and to maintain the liquid level of aerosol generator 11 the insides constant, thereby produce high concentration and the good aerosol of stability of concentration, below aerosol particle 5 μ m, reach 98%, enter into aerosol diluter 12, after the second road air mixed diluting producing with the air compressor 111 entering through the second air flow controller 16 afterwards, from aerosol import, enter into systemic exposure chamber, aerosol is diluted to the concentration that needs contamination, can guarantee that under these circumstances laboratory animal can better carry out toxicological experiment.
On systemic exposure chamber, be provided with pressure transducer 84, humidity sensor 85, temperature sensor 86 and oxygen concentration sensor 87 and sampling of aerosol mouth 89; For detection of the indoor oxygen concentration of systemic exposure, pressure, temperature and humidity and aerosol concentration.
Waste gas reclamation treatment system comprises in turn connected waste gas recovery cylinder 51, filter, exhaust gas flow controller 53, valve, vacuum pump and high altitude discharge processing system.Waste gas recovery cylinder 51 is for reclaiming waste gas, is connected with the waste gas outlet 90 of the second end setting of systemic exposure chamber.
Animal systemic exposure system also comprises sampling system 3 and control system 2.
Sampling system comprises two-position two-way solenoid valve 31, aerosol concentration monitor 33 and aerosol flow controller 34 and the vacuum pump being connected successively.Two-position two-way solenoid valve 31 is connected with sampling of aerosol mouth 89.Aerosol concentration monitor 33 is core components of sampling system, can to the indoor aerosol concentration of systemic exposure, monitor and sampling analysis in real time, to draw experimental data and response curve, for showing that experiment conclusion provides good condition.
Control system comprises industrial PC 21, touch screen computer 22, software programming control terminal 27, data collecting card 23, Control plate 25, catalyst 24 and RS485 communication interface 26; Be used for collecting various parameters, and according to each component working in these parameter conditioning equipments, and regulate the indoor aerocolloidal concentration of systemic exposure, make equipment meet the requirement of experiment.
On data collecting card 23, connect industrial PC 21, under succeed appliance controling plate 25, Control plate 25 connects catalysts 24, catalyst 24 is for controlling the unlatching of all vacuum pumps and air compressor 111 or cutting out.Pressure transducer 84, humidity sensor 85, temperature sensor 86 and oxygen concentration sensor 87 are connected with data collecting card 23.The first air flow controller 17, the second air flow controller 16, exhaust gas flow controller 53, aerosol flow controller 34 are all being connected RS485 communication interface 26 with two-position two-way solenoid valve 31, RS485 communication interface 26 is connecting industrial PC 21, by software programming control terminal 27, to each control hardware terminal coding and send the corresponding command, guaranteed the precision of experiment.Have automation control system, automaticity is high, and experimental precision is high.
Animal systemic exposure system also comprises security mask cabinet and the micro-negative pressure processing system of vacuum.Security mask cabinet comprises the first illuminating lamp, the first ultraviolet disinfecting, USB communication interface and for gathering the thief hatch of aerosol sample.The micro-negative pressure processing system of vacuum is for preventing that the aerosol of a small amount of leakage in security mask cabinet from entering atmosphere; The micro-negative pressure processing system of vacuum comprises check valve 71, Pressure gauge and vacuum pump.
Systemic exposure chamber 88 comprises the conical cavity of the conical cavity of interlude circular cylindrical cavity and upper end and lower end, adopt the exposure chamber cavity of this structure, inner aerocolloidal being more evenly distributed, volume meets internationalization experimental standard more, not only according to pyramidal structure, design, and in accordance with hydrodynamics calculate and computer simulation, it is only ± 2% that the concentration of contamination that can guarantee any point differs.On interlude circular cylindrical cavity cavity wall, be provided with glass door, pressure transducer 84, humidity sensor 85, temperature sensor 86 and oxygen concentration sensor 87 and sampling of aerosol mouth 89.Glass door is for observing the behavior of systemic exposure chamber 88 interior animals, sampling of aerosol mouth 89 is six, three is one group, be arranged on the lower chamber body wall of interlude circular cylindrical cavity, the axis symmetric design of two groups of sampling of aerosol opening's edge interlude circular cylindrical cavities, can detect better the indoor aerocolloidal concentration of systemic exposure, concentration is herein also the concentration that animal sucks position, contributes to observe the reaction of animal under aerosol concentration accurately.In systemic exposure chamber 88, be provided with the second ultraviolet disinfection lamp 81, the second illuminating lamp 82 and animal behavior remote monitoring photographic head 83.
In systemic exposure chamber 88, be also provided with the atomization bubbler 112 being connected with the aerosol import of the first end setting of systemic exposure chamber, for diffusing into the aerosol in systemic exposure chamber 88.On the cavity wall of the conical cavity in lower end, be provided with three waste gas outlets 90, be distributed in the same level on cavity wall, it is stable that this kind is provided with the aerosol concentration being beneficial in systemic exposure chamber 88, prevent that more existing aerofluxus scheme or 2 aerofluxus schemes from causing the inner aerosol in systemic exposure chamber 88 because the mobile aerocolloidal concentration of inside that causes of reason of pressure reduction is unstable, is unfavorable for the carrying out of experiment.
Systemic exposure chamber 88 also comprises the animal wastes collecting processing system that is arranged on bottom, because animal is in the process of experiment, discharge feces possibly, urinate or other material, for the impact on aerosol component of the garbage that prevents the discharge of animal in exposure chamber, also prevent that garbage from impacting animal behavior, also for follow-up easy to clean, animal wastes collecting processing system is set.Animal wastes collecting processing system comprises collecting dung case 61, valve and Waste Water Treatment.Collecting dung case 61 is connected with the Waste outlet of the bottom of the conical cavity in lower end, has feces preliminary treatment material, for collecting ammonia, sulfur dioxide etc. in collecting dung case 61; The bottom of collecting dung case 61 is provided with drainage screen, prevents the pipeline of oarse-grained feces or impurity progress Waste Water Treatment, blocking pipe, the carrying out of impact experiment.
Systemic exposure chamber 88 also comprises purging system, for the systemic exposure chamber after washing test.Purging system comprises the cleaning shower nozzle that cleanout fluid stores conveyer device 44, the first cleaning valve switch 42, the second cleaning valve switch 43, the washer jet 41 being connected with the first cleaning valve switch 42 and is connected with the second cleaning valve switch 43.Washer jet 41 is a plurality of, is arranged on the top of interlude circular cylindrical cavity.
During use, first with the first ultraviolet disinfecting, security mask cabinet is carried out to thorough disinfection and the second ultraviolet disinfecting carries out thorough disinfection to systemic exposure chamber, to test medicinal liquid places in medicinal liquid bottle 13, opening control arranges experiment parameter, comprise medicinal liquid flow, the first air mass flow, the second air mass flow, exhaust gas flow, aerosol flow and negative pressure value etc., after setting completed laboratory animal is put into systemic exposure indoor, open the micro-negative pressure processing system of vacuum, the start button order contamination of then clicking in industrial PC 21 starts.Sampling system is sampled and is obtained aerocolloidal concentration the indoor aerosol of systemic exposure and feeds back to control system.The information that pressure transducer 84 on systemic exposure chamber, humidity sensor 85, temperature sensor 86 and oxygen concentration sensor 87 collect feeds back to control system constantly.Control system regulates entering into the indoor aerosol concentration of systemic exposure according to the indoor oxygen concentration of systemic exposure, pressure, temperature and humidity and aerosol concentration.Waste gas in experiment can filter and discharge through waste gas reclamation treatment system.Test when complete, industrial PC 21 can generate experimental diagrams, for client, analyzes.The unlatching of whole process, adjusting and operation regulation and control all can complete in software programming control terminal 27, realize full-automatic monitoring and operation, make experiment more easy to operate, safety.Full-automation is monitored and is regulated, has waste gas reclamation treatment system; Can prevent that poison from revealing, can carry out sampling, multi-functional powerful animal systemic exposure system in time.Simple to operate, exempted the pollution to operator, improved the precision of safety and contamination.
The above is only preferred implementation of the present utility model; should be understood that; for those skilled in the art, do not departing under the prerequisite of this utility model principle, any improvements and modifications of making also should be considered as protection domain of the present utility model.
Claims (14)
1. an animal systemic exposure system, is characterized in that, comprising:
Systemic exposure chamber, sucks for placing the animal that toxicological experiment is used;
Aerosol generation systems, is communicated with the aerosol of using for generating described suction toxicological experiment with described systemic exposure chamber;
Sampling system, for gathering the indoor aerocolloidal concentration of described systemic exposure;
Waste gas reclamation treatment system, is communicated with described systemic exposure chamber, for the waste gas of described animal generation and unnecessary described aerosol are reclaimed and processed;
Control system, for controlling the indoor described aerocolloidal concentration of described systemic exposure.
2. animal systemic exposure system according to claim 1, it is characterized in that, described aerosol generation systems comprises the air compressor (111) for air is provided, aerosol generator (11), be used for regulating first air flow controller (17) of the air inlet amount of described aerosol generator (11), for the medicinal liquid bottle (13) of medicinal liquid is provided to described aerosol generator (11), for regulating the peristaltic pump (15) of the amount of liquid medicine that enters into described aerosol generator (11), export with the aerosol of described aerosol generator (11) aerosol diluter (12) that is connected and for regulating second air flow controller (16) of the air inlet amount of described aerosol diluter (12), described aerosol diluter (12) is connected with the aerosol import that the first end of described systemic exposure chamber arranges.
3. animal systemic exposure system according to claim 2, it is characterized in that, on described systemic exposure chamber, be provided with pressure transducer (84), humidity sensor (85), temperature sensor (86) and oxygen concentration sensor (87) and sampling of aerosol mouth (89).
4. animal systemic exposure system according to claim 3, it is characterized in that, described waste gas reclamation treatment system comprises in turn connected waste gas recovery cylinder (51), filter, exhaust gas flow controller (53), valve, vacuum pump and high altitude discharge processing system; Described waste gas recovery cylinder (51) is connected with the waste gas outlet (90) that the second end of described systemic exposure chamber arranges.
5. animal systemic exposure system according to claim 3, it is characterized in that, described sampling system comprises two-position two-way solenoid valve (31), aerosol concentration monitor (33) and aerosol flow controller (34) and the vacuum pump being connected successively.
6. according to the animal systemic exposure system described in claim 4 or 5, it is characterized in that, described control system comprises industrial PC (21), touch screen computer (22), software programming control terminal (27), data collecting card (23), Control plate (25), catalyst (24) and RS485 communication interface (26); On described data collecting card (23), connect described industrial PC (21), under connect described Control plate (25), described Control plate (25) connects described catalyst (24), and described catalyst (24) is for controlling the switching of described vacuum pump and described air compressor (111); Described data collecting card (23) is for gathering the indoor pressure of described systemic exposure, humidity, temperature and oxygen concentration; Described software programming control terminal (27) is for coding and send the corresponding command; Described RS485 communication interface (26) is connecting described industrial PC (21).
7. animal systemic exposure system according to claim 6, is characterized in that, also comprises the micro-negative pressure processing system of security mask cabinet and vacuum; Described security mask cabinet is used for installing described systemic exposure chamber, described aerosol generation systems, described sampling system, described waste gas reclamation treatment system and described control system and the micro-negative pressure processing system of described vacuum, and the micro-negative pressure processing system of described vacuum is for preventing that the aerosol of the leakage in described security mask cabinet from entering atmosphere.
8. animal systemic exposure system according to claim 3, is characterized in that, described systemic exposure chamber (88) comprises the conical cavity of the conical cavity of interlude circular cylindrical cavity and upper end and lower end; In described systemic exposure chamber (88), be provided with the atomization bubbler (112) being connected with the aerosol import of the first end setting of described systemic exposure chamber;
On the cavity wall of described interlude circular cylindrical cavity, be provided with described pressure transducer 84, described humidity sensor (85), described temperature sensor (86) and described oxygen concentration sensor (87) and described sampling of aerosol mouth (89).
9. animal systemic exposure system according to claim 8, is characterized in that, described systemic exposure chamber (88) also comprises the animal wastes collecting processing system that is arranged on bottom, is connected with the Waste outlet of the bottom of the conical cavity in described lower end.
10. animal systemic exposure system according to claim 8 or claim 9, is characterized in that, on the cavity wall in the same level of the conical cavity in described lower end, is evenly provided with three waste gas outlets (90).
11. animal systemic exposure systems according to claim 9, is characterized in that, described animal wastes collecting processing system comprises collecting dung case (61) and Waste Water Treatment; Described collecting dung case (61) is connected with described Waste outlet, and the bottom of described collecting dung case (61) is provided with drainage screen; In described collecting dung case (61), there is feces preliminary treatment material.
12. animal systemic exposure systems according to claim 9, is characterized in that, described systemic exposure chamber (88) also comprises purging system, for the systemic exposure chamber after washing test.
13. animal systemic exposure systems according to claim 12, it is characterized in that, described purging system comprises the cleaning shower nozzle that cleanout fluid stores conveyer device (44), the first cleaning valve switch (42), the second cleaning valve switch (43), the washer jet (41) being connected with described the first cleaning valve switch (42) and is connected with described the second cleaning valve switch (43); Described washer jet (41) is a plurality of, is distributed on the top of described interlude circular cylindrical cavity.
14. animal systemic exposure systems according to claim 8, it is characterized in that, in described systemic exposure chamber (88), be provided with the second ultraviolet disinfection lamp (81), the second illuminating lamp (82) and animal behavior remote monitoring photographic head (83).
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104367398A (en) * | 2013-08-13 | 2015-02-25 | 北京慧荣和科技有限公司 | Whole body exposure system for animals |
| CN104546217A (en) * | 2015-01-13 | 2015-04-29 | 张迎梅 | Experimental animal pneumatic atomization dosing device |
| CN105136619A (en) * | 2015-07-29 | 2015-12-09 | 上海市浦东新区气象局 | Artificial climate environment exposure system and use method thereof |
| CN110456833A (en) * | 2019-08-05 | 2019-11-15 | 上海瑞曼信息科技有限公司 | Suck control system, method and the medium of exposure system |
| CN111693409A (en) * | 2020-05-27 | 2020-09-22 | 北京蛙鸣华清环保科技有限公司 | Gas and biological aerosol calibration system and method |
| CN112608827A (en) * | 2020-12-17 | 2021-04-06 | 中国计量科学研究院 | Air microorganism sampler sampling physical efficiency calibration bin, calibration system and method |
| CN112730738A (en) * | 2020-12-07 | 2021-04-30 | 中国科学院深圳先进技术研究院 | Evaluation device and evaluation method for reward and addiction of atomized matter |
| CN113081373A (en) * | 2021-03-12 | 2021-07-09 | 中国石油化工股份有限公司 | Inhalation contamination device for producing intermediate product/byproduct in ethylene glycol synthesis process and application |
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- 2013-08-13 CN CN201320492645.2U patent/CN203539487U/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104367398A (en) * | 2013-08-13 | 2015-02-25 | 北京慧荣和科技有限公司 | Whole body exposure system for animals |
| CN104546217A (en) * | 2015-01-13 | 2015-04-29 | 张迎梅 | Experimental animal pneumatic atomization dosing device |
| CN105136619A (en) * | 2015-07-29 | 2015-12-09 | 上海市浦东新区气象局 | Artificial climate environment exposure system and use method thereof |
| CN105136619B (en) * | 2015-07-29 | 2018-01-26 | 长三角环境气象预报预警中心（上海市环境气象中心） | A kind of artificial climate environmental exposure system and application process |
| CN110456833A (en) * | 2019-08-05 | 2019-11-15 | 上海瑞曼信息科技有限公司 | Suck control system, method and the medium of exposure system |
| CN111693409A (en) * | 2020-05-27 | 2020-09-22 | 北京蛙鸣华清环保科技有限公司 | Gas and biological aerosol calibration system and method |
| CN112730738A (en) * | 2020-12-07 | 2021-04-30 | 中国科学院深圳先进技术研究院 | Evaluation device and evaluation method for reward and addiction of atomized matter |
| CN112608827A (en) * | 2020-12-17 | 2021-04-06 | 中国计量科学研究院 | Air microorganism sampler sampling physical efficiency calibration bin, calibration system and method |
| CN113081373A (en) * | 2021-03-12 | 2021-07-09 | 中国石油化工股份有限公司 | Inhalation contamination device for producing intermediate product/byproduct in ethylene glycol synthesis process and application |
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