CN203749644U - Large animal mouth and nose exposing system - Google Patents
Large animal mouth and nose exposing system Download PDFInfo
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- CN203749644U CN203749644U CN201320727597.0U CN201320727597U CN203749644U CN 203749644 U CN203749644 U CN 203749644U CN 201320727597 U CN201320727597 U CN 201320727597U CN 203749644 U CN203749644 U CN 203749644U
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- large animal
- animal
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- mouth
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Abstract
The utility model provides a large animal mouth and nose exposing system, which comprises an aerosol generator, a computer control device, a first exposing chamber, an animal mask, a second exposing chamber, a waste gas recovery and processing device and a large animal fixing frame, wherein the first exposing chamber is connected with the aerosol generator, the animal mask is used for being installed at the mouse and nose part of a large animal and is connected with the first exposing chamber through a first hose, the second exposing room is connected with the animal mask through a second hose, the waste gas recovery and processing device is connected with the second exposing chamber, the large animal fixing frame is used for fixing the large animal. Through the animal mask arranged at the mouse and nose part of the large animal, the first exposing chamber inputs aerosol through the first hose, the aerosol enters the second exposing chamber through the second hose after being sucked by the large animal in the animal mask, then, the aerosol is processed by the waste gas recovery and processing device, the large animal fixing frame fixes the large animal, the large animal cannot be easily fixed, the large animal fixing frame and the animal mask can be used for realizing the inhalation toxicology experiment of the large animal, and the large animal mouth and nose exposing system is used for exposing experiments of the large animal.
Description
Technical field
This utility model relates to animal and sucks toxicological experiment field, particularly relates to a kind of large animal mouth and nose exposure system.Can be used for sucking the evaluation of toxicity drug safety, pesticide acute toxicity and suck experimentation, the various diseases model that builds animal and its curative effect of medication experimentation, atmosphere pollution to the research of animal breath systematic influence etc.
Background technology
Inhalation toxicology be research can inhalation (inhalatio) to body toxic action occur, development and the various conditions of eliminating, rule and mechanism and to can inhalation (inhalatio) carrying out a science of hazard assessment.Its professional research contents mainly contains: the physicochemical property of various materials in air; The fundamental biological knowledge of respiratory tract; Deposition in vivo of inhalation (inhalatio) and delay and and body in interaction between important system, organ; These interactions are how to cause disease to produce.
Along with international inhalation toxicology research is increasingly active, lot of domestic experts has also been fully recognized that the significance of inhalation toxicology.From the object of research, mainly animal is comprised the research of rat, mice, rabbit, hamster etc.
In recent years, expert has proposed to utilize dog class or sheep class to suck toxicological experiment, studies respiratory medications and airborne contaminants to anthropogenic influence's simulation experiment study and application, because large animal is larger, be difficult for fixing, equipment temporarily not relevant in therefore putting into practice is for large animal exposure experiment.
Utility model content
The purpose of this utility model is that a kind of large animal mouth and nose exposure system will be provided, for the exposure experiment of the large animals such as dog class.
To achieve these goals, this utility model provides a kind of large animal mouth and nose exposure system, comprises aerosol generator and computer controller, wherein, also comprises: the first exposure chamber, is connected with described aerosol generator; For being arranged on the animal face shield at the mouth and nose place of large animal, by the first flexible pipe, be connected with described the first exposure chamber; The second exposure chamber, is connected with described animal face shield by the second flexible pipe; Waste gas recycling and processing device, is connected with described the second exposure chamber; Large animal fixed mount for fixing described large animal.
Preferably, described animal face shield is conical face shield; At the tip of described conical face shield, offer the import with described the first soft pipe connection, on the taper seat of described conical face shield, offer the outlet with described the second soft pipe connection; Opening at described conical face shield is provided with sealing device.
Preferably, in the center of described the first exposure chamber internal cavities, be provided with the aerosol atomizing bubbler being connected with described aerosol generator by the 3rd pipeline; The uniform a plurality of aerosol outlets in same level place on the wall of the chamber of described the first exposure chamber; Described aerosol outlet is connected with described the first flexible pipe.
Preferably, the same level place on the wall of described chamber is also provided with pressure transducer, humidity sensor, temperature sensor and oxygen concentration sensor and the aerosol sampling apparatus being connected with described computer controller.
Preferably, also comprise exposure chamber fixed mount; Described the first exposure chamber is arranged on the upper end of described exposure chamber fixed mount, and described the second exposure chamber is arranged on the lower end of described exposure chamber fixed mount.
Preferably, described waste gas recycling and processing device comprises vacuum pump and waste gas disposal plant.
Preferably, described large animal fixed mount comprises square platform, and four jiaos of described square platform are provided with column.
Preferably, described large animal fixed mount also comprises cross bar, and described cross bar is parallel with the long limit of described square platform, is fixed on two root posts on described long limit.
Preferably, described large animal fixed mount also comprises pulley, be arranged on described square platform below.
Preferably, also comprise shielding cabinet.
Large animal mouth and nose exposure system of the present utility model, due to by being arranged on the animal face shield at large animal mouth and nose place, by the first exposure chamber, by the first flexible pipe, input aerosol, after being sucked by large animal, by the second flexible pipe, enter the second exposure chamber in animal face shield, then by waste gas recycling and processing device, processed, the fixing large animal of large animal fixed mount, because large animal is not easy to be fixed, use large animal fixed mount and animal face shield can realize the suction toxicological experiment of large animal, for the exposure of large animal, test, be that animal can reasonably carry out activity in scope, face shield is connected with aerosol generator by flexible pipe, there is mobility, when therefore testing, need not guarantee that animal is completely motionless, just can test.
Further, animal face shield of the present utility model is conical face shield; At the tip of conical face shield, offer the import with the first soft pipe connection, on the taper seat of conical face shield, offer the outlet with the second soft pipe connection; Opening at conical face shield is provided with sealing device; Can be convenient to aerocolloidal absorption and aerocolloidal circulation.
Further, large animal fixed mount of the present utility model adopts square platform to add the form of column, and the lower part of the body of animal is fixed, and does not affect the activity of the head of animal, is conducive to observe the reflection after large animal Inhaled Aerosol.
According to the detailed description to this utility model specific embodiment by reference to the accompanying drawings below, those skilled in the art will understand above-mentioned and other objects, advantage and feature of the present utility model more.
Accompanying drawing explanation
Hereinafter in exemplary and nonrestrictive mode, describe specific embodiments more of the present utility model in detail with reference to the accompanying drawings.In accompanying drawing, identical Reference numeral has indicated same or similar parts or part.It should be appreciated by those skilled in the art that these accompanying drawings may not draw in proportion.In accompanying drawing:
Fig. 1 is according to the schematic diagram of the large animal mouth and nose of an embodiment exposure system of this utility model;
Fig. 2 is the schematic perspective view of large animal holder shown in Fig. 1;
Reference numeral: aerosol generator 10, computer controller 20, exposure chamber fixed mount 30, the first exposure chamber 31, the second exposure chamber 32, animal face shield 40, the first flexible pipe 41, the second flexible pipes 42, large animal fixed mount 50, square platform 51, column 52, cross bar 53, pulley 54.
The specific embodiment
Fig. 1 is according to the schematic diagram of the large animal mouth and nose of an embodiment exposure system of this utility model.Large animal mouth and nose exposure system, comprising: aerosol generator 10, sucks for generation of large animal the aerosol that toxicity is used; Computer controller 20, for controlling the operation of whole system; The first exposure chamber 31, is connected with aerosol generator 10; Animal face shield 40, is connected with the first exposure chamber 31 by the first flexible pipe 41, for being arranged on the mouth and nose place of large animal; The second exposure chamber 32, is connected with animal face shield 40 by the second flexible pipe 42; Waste gas recycling and processing device, is connected with the second exposure chamber 32, and waste gas recycling and processing device comprises vacuum pump and emission-control equipment; Large animal fixed mount 50 for fixing large animal.During experiment, computer controller 20 starts, control the aerosol that aerosol generator 10 produces desired concn, after the first exposure chamber 31, the first flexible pipe 41, after the large animal of the interior quilt of animal face shield 40 absorbs, the waste gas that large animal is discharged and unnecessary aerosol enter the second exposure chamber 32 through the second flexible pipe 42, then enter waste gas reclamation treatment system and process.This utility model embodiment provides a kind of large animal mouth and nose exposure system, for the exposure experiment of the large animals such as dog class.For expert utilizes the toxicological experiment that sucks of the large animal such as dog class or sheep class, study respiratory medications and airborne contaminants to anthropogenic influence's simulation experiment study and application, the equipment of practice is provided.Due to by being arranged on the animal face shield at large animal mouth and nose place, by the first exposure chamber, by the first flexible pipe, input aerosol, after being sucked by large animal, by the second flexible pipe, enter the second exposure chamber in animal face shield, then by waste gas recycling and processing device, processed, the fixing large animal of large animal fixed mount, because large animal is not easy to be fixed, use large animal fixed mount and animal face shield can realize the suction toxicological experiment of large animal, for the exposure of large animal, test, be that animal can reasonably carry out activity in scope, face shield is connected with aerosol generator by flexible pipe, there is mobility, when therefore testing, need not guarantee that animal is completely motionless, just can test, animal is owing to not being completely fixed, the comfortableness of animal also can be guaranteed.
Large animal mouth and nose exposure system also comprises shielding cabinet, shielding cabinet can only be arranged on the periphery of aerosol generator 10, the first exposure chamber 31, the second exposure chamber 32, waste gas reclamation treatment system and computer controller, also can be arranged on the periphery of aerosol generator 10, the first exposure chamber 31, the second exposure chamber 32, waste gas reclamation treatment system and computer controller and large animal fixed mount 50, aerosol for Leakage prevention enters atmosphere, and experimenter is impacted or atmosphere pollution.
Large animal mouth and nose exposure system also comprises exposure chamber fixed mount 30; The first exposure chamber 31 is arranged on the upper end of exposure chamber fixed mount 30, and the second exposure chamber 32 is arranged on the lower end of described exposure chamber fixed mount 30.Setting up and downly be conducive to aerocolloidal flow, proper height setting up and down is also conducive to the animal attitude of standing and carries out mouth and nose and expose experiment simultaneously.Aerosol generator 10 can be arranged on the upper end of the first exposure chamber 31, also can be arranged on other place, waste gas recycling and processing device can be arranged on the lower end of the second exposure chamber, also can be arranged on exposure chamber fixed mount 30 place in addition, the bottom of fixed mount 30 is provided with mobile device, as mobile pulley etc.
In another one embodiment of the present utility model, animal face shield 40 is conical face shield; At the tip of conical face shield, offer the import being communicated with the first flexible pipe 41, on the taper seat of conical face shield, offer the outlet being communicated with the second flexible pipe 42; Opening at conical face shield is provided with sealing device.Import is arranged on point, is conducive to aerocolloidally enter and absorbed by large animal, and outlet is arranged on from large animal mouth and nose on the taper seat close to more, contributes to the quick outflow of waste gas, prevents contamination gas colloidal sol.
In another one embodiment of the present utility model, in the center of the internal cavities of the first exposure chamber 31, be provided with the aerosol atomizing bubbler being connected with aerosol generator 10 by the 3rd pipeline.The uniform a plurality of aerosol outlets in same level place on the chamber wall of the first exposure chamber 31, are four in the present embodiment; Aerosol outlet is connected with the first flexible pipe 41.A plurality of aerosol outlets are set and are conducive to carry out a plurality of experiments simultaneously.Same level place on the wall of chamber is also provided with pressure transducer, humidity sensor, temperature sensor and oxygen concentration sensor and the aerosol sampling apparatus being connected with computer controller 20.Preferably, pressure transducer and aerosol outlet are in one plane.For detection of pressure, humidity, temperature and oxygen concentration and the aerosol concentration in the first exposure chamber 31, be convenient to control stablizing of aerocolloidal concentration and carrying out smoothly of experiment according to these experimental datas, these checkout gears are arranged on the outlet with aerosol and are arranged in same level, be conducive to detect by the aerosol concentration of animal suction place, more approach the concentration that actual animal sucks.
In another one embodiment of the present utility model, as shown in Figure 2, large animal fixed mount 50 comprises square platform 51, and four jiaos of square platform 51 are provided with column 52.Large animal fixed mount 50 also comprises cross bar 53, and cross bar 53 is parallel with the long limit of square platform 51, is fixed on two root posts 52 on long limit.Large animal fixed mount 50 also comprises pulley 54, be arranged on square platform 51 below.This kind of large animal fixed mount 50, is fixed the lower part of the body of animal, does not affect as far as possible the freedom of animal, shows the free state of animal after Inhaled Aerosol completely.
So far; the above is only preferred implementation of the present utility model, it should be pointed out that for those skilled in the art; do not departing under the prerequisite of this utility model principle, any improvements and modifications of making also should be considered as protection domain of the present utility model.
Claims (10)
1. a large animal mouth and nose exposure system, comprises aerosol generator (10) and computer controller (20), it is characterized in that, also comprises:
The first exposure chamber (31), is connected with described aerosol generator (10);
For being arranged on the animal face shield (40) at the mouth and nose place of large animal, by the first flexible pipe (41), be connected with described the first exposure chamber (31);
The second exposure chamber (32), is connected with described animal face shield (40) by the second flexible pipe (42);
Waste gas recycling and processing device, is connected with described the second exposure chamber (32);
Large animal fixed mount (50) for fixing described large animal.
2. large animal mouth and nose exposure system according to claim 1, is characterized in that, described animal face shield (40) is conical face shield; At the tip of described conical face shield, offer the import being communicated with described the first flexible pipe (41), on the taper seat of described conical face shield, offer the outlet being communicated with described the second flexible pipe (42); Opening at described conical face shield is provided with sealing device.
3. large animal mouth and nose exposure system according to claim 1, it is characterized in that, in the center of the internal cavities of described the first exposure chamber (31), be provided with the aerosol atomizing bubbler being connected with described aerosol generator (10) by the 3rd pipeline; The uniform a plurality of aerosol outlets in same level place on the chamber wall of described the first exposure chamber (31); Described aerosol outlet is connected with described the first flexible pipe (41).
4. large animal mouth and nose exposure system according to claim 3, it is characterized in that, the same level place on the wall of described chamber is also provided with pressure transducer, humidity sensor, temperature sensor and oxygen concentration sensor and the aerosol sampling apparatus being connected with described computer controller (20).
5. large animal mouth and nose exposure system according to claim 3, is characterized in that, also comprises exposure chamber fixed mount (30); Described the first exposure chamber (31) is arranged on the upper end of described exposure chamber fixed mount (30), and described the second exposure chamber (32) is arranged on the lower end of described exposure chamber fixed mount (30).
6. large animal mouth and nose exposure system according to claim 1, is characterized in that, described waste gas recycling and processing device comprises vacuum pump and waste gas disposal plant.
7. according to the large animal mouth and nose exposure system described in any one in claim 1 to 6, it is characterized in that, described large animal fixed mount (50) comprises square platform (51), and four jiaos of described square platform (51) are provided with column (52).
8. large animal mouth and nose exposure system according to claim 7, it is characterized in that, described large animal fixed mount (50) also comprises cross bar (53), described cross bar (53) is parallel with the long limit of described square platform (51), is fixed on two root posts (52) on described long limit.
9. large animal mouth and nose exposure system according to claim 7, is characterized in that, described large animal fixed mount (50) also comprises pulley (54), be arranged on described square platform (51) below.
10. according to the large animal mouth and nose exposure system described in any one in claim 1 to 6, it is characterized in that, also comprise shielding cabinet.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201320727597.0U CN203749644U (en) | 2013-11-15 | 2013-11-15 | Large animal mouth and nose exposing system |
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CN201320727597.0U CN203749644U (en) | 2013-11-15 | 2013-11-15 | Large animal mouth and nose exposing system |
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CN203749644U true CN203749644U (en) | 2014-08-06 |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104305997A (en) * | 2014-08-21 | 2015-01-28 | 华南理工大学 | Device for detecting pulmonary function of creatures |
CN105287042A (en) * | 2015-12-03 | 2016-02-03 | 陈晓阳 | Animal smog inhaling device |
CN109512545A (en) * | 2017-09-19 | 2019-03-26 | 中国人民解放军军事科学院军事医学研究院微生物流行病研究所 | The big animal organism aerosol mouth and nose exposure system of biological safe type primate |
CN110269721A (en) * | 2018-03-15 | 2019-09-24 | 北京慧荣和科技有限公司 | Big animal mouth and nose exposure system |
CN110269719A (en) * | 2018-03-15 | 2019-09-24 | 北京慧荣和科技有限公司 | The multi-functional fixed vehicle of animal |
CN110456833A (en) * | 2019-08-05 | 2019-11-15 | 上海瑞曼信息科技有限公司 | Suck control system, method and the medium of exposure system |
-
2013
- 2013-11-15 CN CN201320727597.0U patent/CN203749644U/en not_active Expired - Fee Related
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104305997A (en) * | 2014-08-21 | 2015-01-28 | 华南理工大学 | Device for detecting pulmonary function of creatures |
CN105287042A (en) * | 2015-12-03 | 2016-02-03 | 陈晓阳 | Animal smog inhaling device |
CN105287042B (en) * | 2015-12-03 | 2017-07-28 | 陈晓阳 | Animal smoke inhalation device |
CN109512545A (en) * | 2017-09-19 | 2019-03-26 | 中国人民解放军军事科学院军事医学研究院微生物流行病研究所 | The big animal organism aerosol mouth and nose exposure system of biological safe type primate |
CN109512545B (en) * | 2017-09-19 | 2024-07-09 | 中国人民解放军军事科学院军事医学研究院微生物流行病研究所 | Biological safety type primate biological aerosol oral-nasal exposure system |
CN110269721A (en) * | 2018-03-15 | 2019-09-24 | 北京慧荣和科技有限公司 | Big animal mouth and nose exposure system |
CN110269719A (en) * | 2018-03-15 | 2019-09-24 | 北京慧荣和科技有限公司 | The multi-functional fixed vehicle of animal |
CN110456833A (en) * | 2019-08-05 | 2019-11-15 | 上海瑞曼信息科技有限公司 | Suck control system, method and the medium of exposure system |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140806 Termination date: 20181115 |
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CF01 | Termination of patent right due to non-payment of annual fee |