Sample needle assembly for full-automatic chemiluminescence immunoassay analyzer
Technical Field
The utility model belongs to the technical field of medical equipment, and particularly relates to a sample needle assembly for a full-automatic chemiluminescence immunoassay analyzer.
Background
Chemiluminescence immunoassay (CLIA) is a detection and analysis technology combining chemiluminescence assay technology with high sensitivity and high specificity immunoreaction, is used for detecting and analyzing various antigens, haptens, antibodies, hormones, enzymes, fatty acids, vitamins, medicaments and the like, is a latest immunoassay technology developed after radioimmunoassay, enzyme immunoassay, fluorescence immunoassay and time-resolved fluorescence immunoassay, has the advantages of high sensitivity, wide detection range, good marker stability and the like, and is a main detection method in the immunoassay field.
Chinese patent document CN113504380A discloses a full-automatic chemiluminescence immunoassay analyzer, in which a sample filling module rotates a sample needle to a sampling position of a transfer rail module, the sample needle is inserted into a liquid level for sampling, and after sampling is completed, the sample needle is lifted and rotated to the sampling position of a reaction disk module for sampling.
However, in the above technical scheme of the patent document, in the actual use process, if the sample needle is empty in the sample test tube, the empty suction cannot be detected in time, which causes the detection data to be wrong, and the effect is not ideal.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a sample needle assembly for a full-automatic chemiluminescence immunoassay analyzer, which can detect the pressure in a sample needle and avoid data detection errors caused by suction.
In order to solve the technical problems, the utility model adopts the technical scheme that the sample needle assembly for the full-automatic chemiluminescence immunoassay analyzer comprises a sample fixing assembly, wherein the sample fixing assembly is used for pressing and fixing a sample test tube; the sampling assembly is provided with a sample needle for sucking a sample from a sample test tube fixed by the sample fixing assembly and moving the sample into a reaction cup; the sampling assembly is further provided with a pressure detection block, and the pressure detection block is used for detecting the pressure in the sample needle.
The sample is positioned in the sample test tube, when the sample is in place, the sample fixing assembly presses down the fixed sample test tube, after the sampling assembly moves right above the sample test tube, the sample needle absorbs a certain amount of sample, lifts and moves to the reaction cup on the other side, then moves to the sample needle cleaning station for cleaning, and the actions are sequentially circulated; the sample fixing component can fix the test tube and prevent the sample test tube from moving when the test tube is punctured; the pressure detection block can detect the pressure in the sample needle tube, and the error of detection data caused by air suction is avoided.
Preferably, a puncture needle is further arranged in the sample needle, and the puncture needle penetrates through the sample needle to puncture a sample test tube; the sample test tube is punctured by the puncture needle, and the needle head is prevented from being damaged.
Preferably, the sampling assembly is driven by a sampling Y-axis motion assembly to perform Y-axis motion, and the sampling assembly further has a sample needle Z-axis motion assembly, and the sample needle Z-axis motion assembly drives the sample needle to perform Z-axis motion.
Preferably, the sampling Y-axis movement assembly comprises a Y-axis movement slide rail, and the sampling assembly moves on the Y-axis movement slide rail through a Y-axis movement slide block; the sampling Y-axis motion assembly further comprises a Y-axis motion motor, the Y-axis motion motor drives the Y-axis motion driving wheel to rotate, the Y-axis motion driving wheel drives the Y-axis motion driven wheel through a Y-axis motion belt, and the Y-axis motion belt is connected with the sampling assembly.
Preferably, the sample needle Z-axis movement assembly comprises a sample needle Z-axis movement screw rod motor, the sample needle Z-axis movement screw rod motor drives a screw rod to rotate, the sample needle is mounted on a sample needle driving block, and the sample needle driving block is sleeved on the screw rod; the sample needle driving block is also connected with a sample needle Z-axis moving slide block, and the sample needle Z-axis moving slide block performs Z-axis movement on the sample needle Z-axis moving slide rail.
Preferably, a sample needle limiting baffle is arranged on the sample needle driving block, and a sample needle limiting optocoupler matched with the sample needle limiting baffle is arranged at the end part of the sample needle Z-axis movement sliding rail.
Preferably, the sample fixing assembly comprises a sample tube Z-axis moving assembly, and the sample tube Z-axis moving assembly drives the sample tube to perform Z-axis movement.
Preferably, the sample test tube Z-axis movement assembly comprises a sample test tube Z-axis movement motor, the sample test tube Z-axis movement motor drives a sample test tube Z-axis movement driving wheel to rotate, the sample test tube Z-axis movement driving wheel drives a sample test tube Z-axis movement driven wheel through a sample test tube Z-axis movement belt, the sample test tube Z-axis movement belt is connected with a test tube pressing arm, and the test tube pressing arm performs Z-axis movement on a sample test tube Z-axis movement slide rail through a sample test tube Z-axis movement slider; the sample tube is fixed on the tube pressing arm.
Preferably, the test tube pressing arm is provided with a sample test tube limiting blocking piece, and a sample test tube limiting optocoupler assembled with the sample test tube limiting blocking piece is arranged at the end part of the sample test tube Z-axis movement sliding rail.
Preferably, the sampling assembly is further provided with a liquid level detection plate, and the liquid level detection plate is used for detecting the liquid level state in the sample test tube.
Drawings
The following further detailed description of embodiments of the utility model is made with reference to the accompanying drawings:
FIG. 1 is a schematic structural view of a sample needle assembly for use in a full-automatic chemiluminescence immunoassay analyzer according to the present invention;
FIG. 2 is a schematic view of the sampling assembly of FIG. 1;
FIG. 3 is a schematic view of the sample holding assembly of FIG. 1;
FIG. 4 is an enlarged partial schematic view of the specimen mount assembly of FIG. 3;
FIG. 5 is a schematic view of the backside structure of FIG. 1;
wherein: 1-a sample fixing component, 101-a sample test tube Z-axis moving component, 10101-a sample test tube Z-axis moving motor, 10102-a sample test tube Z-axis moving driving wheel, 10103-a sample test tube Z-axis moving belt, 10104-a sample test tube Z-axis moving driven wheel, 102-a test tube pressing arm, 10105-a sample test tube Z-axis moving sliding block, 10106-a sample test tube Z-axis moving sliding rail, 10201-a sample test tube limiting blocking piece and 10202-a sample test tube limiting optical coupler; 2-sample tube; 3-sampling assembly, 301-sample needle, 302-pressure detection block, 303-puncture needle, 304-sampling Y-axis movement assembly, 30401-Y-axis movement slide rail, 30402-Y-axis movement slide block, 30403-Y-axis movement motor, 30404-Y-axis movement driving wheel, 30405-Y-axis movement belt, 30406-Y-axis movement driven wheel, 305-sample needle Z-axis movement assembly, 30501-sample needle Z-axis movement lead screw motor, 30502-lead screw, 30503-sample needle driving block, 30504-sample needle Z-axis movement slide block, 30505-sample needle Z-axis movement slide rail, 30506-sample needle limiting baffle plate, 30507-sample needle limiting optical coupler and 306-liquid level detection plate.
Detailed Description
As shown in fig. 1 and 5, the sample needle assembly for a full-automatic chemiluminescence immunoassay analyzer of the embodiment comprises a sample fixing assembly 1, wherein the sample fixing assembly 1 is used for pressing down and fixing a sample test tube 2; a sampling assembly 3 is further included, the sampling assembly 3 is provided with a sample needle 301 for sucking a sample from the sample test tube 2 fixed by the sample fixing assembly 1 and moving the sample into a reaction cup; the sampling assembly 3 is further provided with a pressure detection block 302, and the pressure detection block 302 is used for detecting the pressure in the sample needle 301.
A puncture needle 303 is further disposed in the sample needle, as shown in fig. 1 and 2, the puncture needle 303 penetrates through the sample needle 301 to puncture the sample tube 2.
The sampling assembly 3 is driven by a sampling Y-axis movement assembly 304 to perform Y-axis movement, as shown in FIGS. 1 and 2, the sampling assembly 3 further comprises a sample needle Z-axis movement assembly 305, and the sample needle 301 is driven by the sample needle Z-axis movement assembly 305 to perform Z-axis movement; the direction of the sample needle 301 is adjusted through the movement of the Y axis and the Z axis, so that the sampling and the sample adding can be carried out smoothly.
The sampling Y-axis moving assembly 304 comprises a Y-axis moving slide rail 30401, and the sampling assembly 3 moves on the Y-axis moving slide rail 30401 through a Y-axis moving slider 30402; the sampling Y-axis motion assembly 304 further includes a Y-axis motion motor 30403, the Y-axis motion motor 30403 drives a Y-axis motion driving wheel 30404 to rotate, the Y-axis motion driving wheel 30404 drives a Y-axis motion driven wheel 30406 through a Y-axis motion belt 30405, and the Y-axis motion belt 30405 is connected to the sampling assembly 3.
The sample needle Z-axis motion assembly 305 comprises a sample needle Z-axis motion screw rod motor 30501, the sample needle Z-axis motion screw rod motor 30501 drives a screw rod 30502 to rotate, the sample needle 301 is mounted on a sample needle driving block 30503, and the sample needle driving block 30503 is sleeved on the screw rod 30502; the sample needle driving block 30503 is further connected with a sample needle Z-axis movement slider 30504, and the sample needle Z-axis movement slider 30504 performs Z-axis movement on the sample needle Z-axis movement slide 30505.
The sample needle driving block 30503 is provided with a sample needle limiting blocking piece 30506, the end part of the sample needle Z-axis movement sliding rail is provided with a sample needle limiting optocoupler 30507 matched with the sample needle limiting blocking piece 30506, and the movement position of the sample needle driving block 30503 on the sample needle Z-axis movement sliding rail 30505 is limited.
The sample fixing assembly 1 includes a sample tube Z-axis moving assembly 101, and the sample tube Z-axis moving assembly 101 drives the sample tube 2 to perform Z-axis movement.
The sample test tube Z-axis movement assembly 101 comprises a sample test tube Z-axis movement motor 10101, the sample test tube Z-axis movement driving wheel 10102 is driven to rotate by the sample test tube Z-axis movement motor 10101, the sample test tube Z-axis movement driving wheel 10102 drives a sample test tube Z-axis movement driven wheel 10104 through a sample test tube Z-axis movement belt 10103, the sample test tube Z-axis movement belt 10103 is connected with a test tube pressure arm 102, and the test tube pressure arm 102 performs Z-axis movement on a sample test tube Z-axis movement sliding rail 10106 through a sample test tube Z-axis movement slider 10105; the sample tube 2 is fixed to the tube press arm 102.
The test tube pressure arm 102 is provided with a sample test tube limiting blocking piece 10201, and the end part of the sample test tube Z-axis movement sliding rail 10106 is provided with a sample test tube limiting optical coupler 10202 assembled with the sample test tube limiting blocking piece 10201.
The sampling assembly 3 is further provided with a liquid level detection plate 306, and the liquid level detection plate 306 is used for detecting the liquid level state in the sample test tube 2.
The sample needle 301 of this embodiment is mainly used to suck a patient sample, a quality control product, and a calibration product into a reaction cup, and after the sample is added, the sample needle moves to a sample needle cleaning station to clean the inner and outer walls, and the intensive cleaning is performed on a severely contaminated project. The sample needle 301 has automatic liquid level detection (realized by the liquid level detection plate 306), suction detection (realized by the pressure detection block 302) and puncture function (realized by the puncture needle 303).
The working principle of the sample needle assembly for the full-automatic chemiluminescence immunoassay analyzer is as follows: the synchronous belt transmission system is driven by the stepping motor to drive the sampling component 3 and the sample fixing component 1 to respectively move linearly on the Y-axis slide rail and the Z-axis slide rail. When the sample test tube is in place, the test tube pressing arm 102 in the sample fixing assembly 1 presses down and fixes the sample test tube 2, after the sampling assembly 3 moves to the position right above the sample test tube, the sample needle Z-axis movement screw rod motor 30501 drives the sample needle driving block 30503 to move downwards along the Z-axis, after the puncture needle 303 penetrates through the sample test tube 2 and the liquid level detection plate 306 detects that the puncture needle contacts the liquid level, the sample needle 301 sucks a certain amount of sample, lifts and moves to the reaction cup on the other side, moves to the sample needle cleaning station for cleaning, and sequentially circulates the actions. The sample fixing assembly 1 can fix the sample test tube 2 and prevent the sample test tube 2 from moving when being punctured; the liquid level detection plate 306 ensures that the puncture needle 303 does not touch the bottom to damage the needle head of the sample needle 301; the pressure detection block 302 can detect the pressure in the sample needle 301, and avoid the occurrence of air suction to cause detection data errors.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the utility model as claimed. The scope of the utility model is defined by the appended claims and equivalents thereof.