CN114152766B - Sample analyzer and manual sample feeding assembly thereof - Google Patents

Sample analyzer and manual sample feeding assembly thereof Download PDF

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Publication number
CN114152766B
CN114152766B CN202210123548.XA CN202210123548A CN114152766B CN 114152766 B CN114152766 B CN 114152766B CN 202210123548 A CN202210123548 A CN 202210123548A CN 114152766 B CN114152766 B CN 114152766B
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China
Prior art keywords
sample
manual
sliding
guide section
feeding assembly
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CN202210123548.XA
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Chinese (zh)
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CN114152766A (en
Inventor
张勇
肖华
农扬就
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Shenzhen Dymind Biotechnology Co Ltd
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Shenzhen Dymind Biotechnology Co Ltd
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Publication of CN114152766A publication Critical patent/CN114152766A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/0092Scheduling
    • G01N35/0095Scheduling introducing urgent samples with priority, e.g. Short Turn Around Time Samples [STATS]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065Multiple transfer devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0418Plate elements with several rows of samples
    • G01N2035/042Plate elements with several rows of samples moved independently, e.g. by fork manipulator

Abstract

The invention discloses a sample analyzer and a manual sample feeding assembly thereof, wherein the manual sample feeding assembly comprises a first sample seat, a first driving part for driving the first sample seat to move and a track for guiding the first sample seat to move, the track comprises a first guide section extending along the Y direction and a second guide section arranged at an angle relative to the Y direction, the first sample seat moves between a first sample placing position and a second sample placing position under the action of the first guide section and moves between the first sample placing position and an initial position under the action of the second guide section, and the initial position is offset at one side of a connecting line of the first sample placing position and the second sample placing position.

Description

Sample analyzer and manual sample feeding assembly thereof
Technical Field
The invention relates to the technical field of sample analysis, in particular to a sample analyzer and a manual sample feeding assembly thereof.
Background
The sample analyzer is the most commonly used blood cell analyzer, which performs statistical analysis on various cells in a blood sample, such as red blood cells, white blood cells, platelets, hemoglobin, and the like by means of a reagent, and provides a basis for diagnosis and treatment of diseases.
Along with sample analysis appearance degree of automation is higher and higher, and more analysis appearance adopts automatic batch to advance the appearance mode, and the user places a plurality of test tubes on the test-tube rack, and the test-tube rack transports the test tube to the appearance position of putting of analysis appearance in batches, can effectively reduce user's operation, accelerate detection speed. However, in the automatic batch sample injection mode, the sample tubes can only be sequentially detected one by one, which is not suitable for some emergency test tubes requiring preferential detection, and therefore some sample analyzers are also configured with a manual sample injection mode, and users can manually place the emergency test tubes at sample placement positions when preferential detection demands exist.
However, in practical operation, the sample placement position is often occupied by the test tube under test when the emergency test tube is manually placed, and the user needs to wait for the whole test procedure of the test tube to be completed before placing the test tube into the emergency test tube, so that the waiting time for the test of the emergency sample is increased, the time for the patient to wait for the test result is also increased, and the risk of contamination of the emergency test tube is also increased.
Disclosure of Invention
In view of this, a sample analyzer and a manual sample feeding assembly thereof are provided.
The invention provides a manual sample feeding assembly which comprises a first sample seat, a first driving piece and a track, wherein the first driving piece drives the first sample seat to move, the track guides the first sample seat to move, the track comprises a first guide section extending along the Y direction and a second guide section arranged at an angle relative to the Y direction, the first sample seat moves between a first sample placing position and a second sample placing position under the action of the first guide section and moves between the first sample placing position and an initial position under the action of the second guide section, and the initial position is offset to one side of a connecting line of the first sample placing position and the second sample placing position.
The invention also provides a sample analyzer, which comprises an automatic sample introduction assembly and the manual sample introduction assembly, wherein the automatic sample introduction assembly conveys a test tube rack loaded with a tube to be tested to a first sample placing position along an automatic sample introduction path in the X direction.
Compared with the prior art, the sample analyzer is provided with the automatic sample feeding assembly and the manual sample feeding assembly which are mutually independent, the first sample seat of the manual sample feeding assembly and the transferring assembly are mutually staggered in the initial state, the first sample seat automatically realizes orbit change through the special design of the track in the process of moving forwards to the second sample placing position, the structure is simple on the whole, the operation is convenient, the operation of the automatic sample feeding assembly, the manual sample feeding assembly, the transferring assembly and the like can be well coordinated, a user can start the manual sample feeding assembly to place an emergency test tube for detection, the risk that emergency samples are polluted is avoided, the rapid transfer of the emergency samples can be realized through the structure, and the waiting time of patients is shortened.
Drawings
FIG. 1 is a schematic diagram of an embodiment of a sample analyzer of the present invention.
Fig. 2 is a schematic structural diagram of a manual sample injection assembly of the sample analyzer shown in fig. 1.
Fig. 3 is a side view of the manual sample injection assembly shown in fig. 2.
Fig. 4 is a top view of the manual sample injection assembly shown in fig. 2.
FIG. 5 is a schematic view of the manual sample injection assembly shown in FIG. 2 at a second sample placement position.
Fig. 6 is a top view of fig. 5.
Fig. 7 is a schematic view of the manual sample injection assembly shown in fig. 2 at a first sample placement position.
Fig. 8 is a top view of fig. 7.
Fig. 9 is a schematic view of a manual sample injection assembly according to a second embodiment of the present invention.
Fig. 10 is a side view of the manual sample injection assembly of fig. 9.
Fig. 11 is a top view of the manual sample injection assembly shown in fig. 9.
Fig. 12 is a schematic view of the manual sample injection assembly shown in fig. 9 at a second sample placement position.
Fig. 13 is a schematic view of the manual sample injection assembly shown in fig. 9 at a first sample placement position.
Fig. 14 is a schematic view of a manual sample injection assembly according to a third embodiment of the present invention.
Fig. 15 is a side view of the manual feed assembly of fig. 14.
Fig. 16 is a top view of the manual sample injection assembly of fig. 14.
Fig. 17 is a schematic view of the manual sample feeding assembly shown in fig. 14 at a second sample setting position.
Fig. 18 is a schematic view of the manual sample injection assembly shown in fig. 14 at a first sample placement position.
Fig. 19 is a schematic view of a manual sample injection assembly according to a fourth embodiment of the present invention.
Fig. 20 is a side view of the manual sample injection assembly of fig. 19.
Fig. 21 is a top view of the manual sample injection assembly of fig. 19.
Fig. 22 is a schematic view of the manual sample feeding assembly shown in fig. 19 at a second sample setting position.
FIG. 23 is a schematic view of the manual sample injection assembly shown in FIG. 19 in a first sample position.
Fig. 24 is a schematic view of a fifth embodiment of a manual sample injection assembly according to the present invention.
Fig. 25 is a side view of the manual sample injection assembly of fig. 24.
Fig. 26 is a top view of the manual sample injection assembly of fig. 24.
FIG. 27 is a schematic view of the manual sample injection assembly of FIG. 24 in a second sample position.
Fig. 28 is a schematic view of the manual sample injection assembly shown in fig. 24 in a first sample position.
Detailed Description
To facilitate an understanding of the invention, the invention will now be described more fully with reference to the accompanying drawings. One or more embodiments of the present invention are illustrated in the accompanying drawings to provide a more accurate and thorough understanding of the disclosed embodiments. It should be understood, however, that the present invention may be embodied in many different forms and should not be construed as being limited to the embodiments set forth herein.
The same or similar reference numbers in the drawings correspond to the same or similar parts; in the description of the present invention, it should be understood that if there is an orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", etc. based on the orientation or positional relationship shown in the drawings, it is only for convenience of describing the present invention and simplifying the description, but it is not intended to indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and are not to be construed as limiting the present patent, and the specific meaning of the terms may be understood by those skilled in the art according to specific circumstances.
The invention provides a sample analyzer, which is used for detecting and analyzing a biological sample, in particular a blood sample. Fig. 1-8 show an embodiment of the sample analyzer of the present invention, which includes a plurality of components, such as an automatic sample feeding component 10, a manual sample feeding component 20, a mixing component 30, a transferring component 40, a sampling component 50, a detecting component, and a control component, wherein the control component is configured to automatically coordinate operations of other components in the whole detecting process. For the convenience of description of the present invention, the following description is assisted by XYZ three-dimensional coordinates, specifically, a side of the sample analyzer facing a user when in use is a front side, a side facing away from the user is a rear side, and a front-back direction is a Y direction of the drawing; the X direction in the figure is the left-right direction, and the Z direction in the figure is the up-down direction.
The automatic sample feeding assembly 10 is disposed outside the main body of the sample analyzer and located at the front side of the main body, and moves along an automatic sample feeding path 12 extending along an X direction to transport a test tube 14 carrying a biological sample to be tested toward a first sample position a of the main body. The manual sample feeding assembly 20 is disposed in the main body of the sample analyzer, and can be extended out to the second sample placing position B from the front side of the main body or retracted inward into the main body, so as to transport the test tube 14 manually placed at the second sample placing position B by the user, such as the emergency test tube 14 requiring preferential detection, to the first sample placing position a. In this embodiment, the second sample placement position B and the first sample placement position a are arranged back and forth along the Y direction, and the second sample placement position B is located in front of the first sample placement position a, and a front housing of the host is provided with a corresponding window for the manual sample feeding assembly 20 to move inside and outside the host in a telescopic manner.
In the autosampler mode, a plurality of test tubes 14 are usually placed on the same test tube rack 16, and the test tube rack 16 moves along the autosampler path 12 to transport the test tubes 14 to be tested in batch to the first sample placement position a. Each test tube 14 is pasted with a bar code to record the information of the corresponding personnel, and the automatic sample feeding path 12 is provided with a bar code scanner to automatically identify the bar code on the test tube 14, so that the detection result can be automatically matched with the corresponding personnel. Preferably, a loading platform 18 and an unloading platform 19 are respectively disposed at the left end and the right end of the automatic sample introduction path 12, and the test tube rack 16 is fed into the automatic sample introduction path 12 from the loading platform 18 and then moved to the first sample placement position a along the automatic sample introduction path 12. After the blending assembly 30 grabs the test tubes 14 on the test tube rack 16, the test tube rack 16 continues to move along the autosampler path 12 to the unloading platform 19 and is unloaded at the unloading platform 19, loading the next batch of test tubes 14.
As shown in fig. 2-4, the manual sample injection assembly 20 includes a first sample holder 22, a first drive member 24, and a first slide 26 and a second slide 28 connected between the first sample holder 22 and the first drive member 24.
In the illustrated embodiment, the first sample holder 22 is provided with two first sample positions 23 for respectively holding two different types of test tubes 14, such as a normal test tube and a micro test tube. The microtubes 14 are much smaller in height and volume than the normal tubes 14, and the mixing means used by the mixing assembly 30, the height at which the sampling assembly 50 pierces for sampling, etc. will vary in subsequent steps. In the examination of blood samples, a conventional test tube 14 is typically used to contain a relatively large volume of venous blood; the micropipette 14 contains peripheral blood of a relatively small amount of blood collected. Preferably, the sample analyzer is provided with a test tube type detecting component, or a user can manually input the test tube type, and the control component generates a corresponding control signal according to the test tube type to start the blending component 30, the sampling component 50 and the like to perform corresponding operations.
The first drive 24 is preferably a lead screw motor that moves the first slide 26 back and forth in the Y direction. In this embodiment, the first sliding member 26 is a sliding rail movably disposed in the first sliding slot 270 of the first sliding block 27, and the first sliding slot 270 extends along the Y direction to guide the movement of the first sliding member 26. The first sliding part 26 is in transmission connection with the first driving part 24 through a first connecting part 25, a screw hole is formed in the center of the first connecting part 25 and is in threaded connection with a screw rod of the first driving part 24, and the rotation of the screw rod is converted into the linear motion of the first sliding part 26 along the Y direction. In other embodiments, the first sliding member 26 may also be a movable sliding block, and at this time, the sliding rail may be fixed to guide the movement of the sliding block; alternatively, the guide mechanism may not be provided. In addition, the first driving member 24 may also be a rotating motor, and the conversion between the rotation and the linear movement is realized through a transmission element such as a gear rack.
The front end of the second slider 28 is provided with the first sample holder 22, the rear end is slidably connected with the first slider 26, as shown in the figure, the first slider 26 is provided with a transverse slide rail 260 extending along the X direction, the second slider 28 is used as a slider, and a second slide slot 280 is formed at the rear end of the second slider 28 and is inserted into the transverse slide rail 260, so that the second slider 28 and the first sample holder 22 can move back and forth along the Y direction along with the first slider 26 and can also move transversely in the X direction relative to the first slider 26, that is, the first sample holder 22 can move in both directions X, Y. In other embodiments, a second sliding groove may be provided on the first slider 26, and a corresponding transverse sliding rail extending in the X direction may be provided on the second slider 28 to cooperate with the second sliding groove, as long as the first slider 26 and the second slider 28 can move relative to each other in the X direction.
As shown in fig. 4, the bottom of the second slider 28 is provided with a sliding portion 282 at a position near the trailing end thereof, and the sliding portion 282 is a roller in the illustrated embodiment. Accordingly, the manual feeding assembly 20 further includes a track 29 for guiding the movement of the sliding part 282, and the track 29 is a groove structure including a first guide section 290, a second guide section 292 and a third guide section 294 connected in sequence. The first guide section 290 and the third guide section 294 extend along the Y direction, and are arranged in parallel at intervals and staggered by a certain distance in the X direction; the second guide section 292 is inclined at an angle with respect to the Y direction and is connected between the first guide section 290 and the third guide section 294 by a bend. The first guide segment 290 is located right behind the first sample position a in the Y direction; the second guide section 292 extends rearward from the rear end of the first guide section 290; the third guide section 294 extends rearward from the rear end of the second guide section 292, and is disposed in the same direction as the moving path of the first slider 26.
As shown in fig. 2 to 4, when the manual sampling assembly 20 is in the initial position D, the first sample seat 22 and the second slide 28 are located on the moving path of the first slide 26, and are laterally offset from the first sample position a. When the manual sampling assembly 20 is started, the first driving member 24 drives the first sliding member 26 to move forward, and first, the second sliding member 28 and the first sample holder 22 move forward along the third guiding section 294 synchronously along with the first sliding member 26, and moving paths of the first sliding member 28 and the first sample holder 22 are in the same straight line; thereafter, as shown in fig. 5 to 6, when the sliding portion 282 of the second slider 28 reaches the second guide section 292 of the rail 29, the inclined second guide section 292 causes the sliding portion 282 to be displaced in both directions X, Y, so that the second slider 28 moves laterally relative to the first slider 26 while moving forward in synchronization with the first slider 26, causing the first sample holder 22 to be displaced in the X direction and reach the first set-up position a; finally, when the sliding portion 282 reaches the first guiding segment 290 of the track 29, the second slide 28 continues to move forward along the first guiding segment 290 until the first sample seat 22 reaches the second sample position B, as shown in fig. 7-8, during which the first slide 26 and the second slide 28 move synchronously but with their moving paths parallel to and spaced from each other.
The transfer assembly 40 comprises a second sample holder 42 and a second driving member 44 for driving the second sample holder 42, wherein the second sample holder 42 is provided with two second sample positions 43 for respectively holding two different types of test tubes 14; the second driving member 44 is preferably a screw motor for driving the second sample holder 42 to move along a transfer path in the Y direction between the first sample placing position a and the sample sucking position C. In this embodiment, the sample sucking position C is located right behind the first sample positioning position a in the Y direction. The second sample holder 42 is fixed to a slide 46, and the slide 46 is drivingly connected to the second driving member 44 through a second connecting member 48. A threaded hole is formed in the center of the second link 48 to be screwed with the lead screw of the second driver 44, and the rotation of the lead screw is converted into the linear movement of the second slider 28 in the Y direction. Similarly, the second driving member 44 may also be a rotating motor, and the conversion of the rotation and the linear movement is realized by a transmission element such as a gear, a rack and the like.
In this embodiment, the transferring assembly 40 and the manual sampling assembly 20 are disposed on a supporting plate 60, and the screws of the first driving member 24 and the second driving member 44 are disposed along the Y direction, and are parallel to each other and spaced apart from each other in the X direction. Under the action of the second driving member 44, the second sample holder 42 moves along the Y-direction transfer path between the first sample setting position a and the sample aspirating position C. Under the action of the first driving member 24, the first sample holder 22 moves along the first guide section 290 in the Y direction, i.e., along the first moving path between the first sample setting position a and the second sample setting position B; the first sample holder 22 is displaced in both directions X, Y along a second path of movement, i.e., along the second guide section 292, between the first sample position a and the initial position D. That is, the moving path of the first sample holder 22 partially overlaps and partially does not overlap with the moving path of the second sample holder 42, and the track 29 is provided to allow the first sample holder 22 to realize the track change during the moving process and avoid the second sample holder 42.
When the sample analyzer of the present invention is used, an automatic sample feeding mode is generally adopted, that is, the automatic sample feeding assembly 10 drives the test tube rack 16 to move along the X direction toward the first sample placing position a to transport the test tube 14. At this time, the manual sampling assembly 20 is maintained at the initial position D shown in fig. 2 to 4, and the first sample holder 22 is located on the moving path of the first slider 26, completely staggered from the second sample holder 42 and the moving path thereof. When the emergency test tube 14 needs to be preferentially detected, the user can start the manual sample injection mode through the host, and the manual sample injection assembly 20 drives the first sample holder 22 to move so as to move the emergency test tube 14 from the second sample placement position B to the first sample placement position a. Before the manual sampling assembly 20 is activated, the control assembly may activate the second driving member 44 to drive the second sample holder 42 to move backward a certain distance to leave the first sample position a, as shown in fig. 3. When the transfer module 40 is loaded with the tubes 14 to be tested, it can be moved back to the sample suction position C.
Specifically, the control assembly activates the first driving member 24 to move the first sliding member 26 forward, so as to drive the first specimen holder 22 to move forward, the first specimen holder 22 is displaced in the X direction by the second guiding section 292 of the track 29 during the forward movement, and the first specimen holder 22 moves to the right front of the second specimen holder 42 and continues to move along the first guiding section 290 to the second sample placement position B to receive the manually inserted emergency test tube 14, as shown in fig. 7-8. Thereafter, as shown in fig. 5-6, the first driving member 24 rotates in the reverse direction to move the first sliding member 26 a certain distance backward, so as to drive the first specimen holder 22 to move backward along the first guiding section 290 to the tail end of the first guiding section 290, and the first specimen holder 22 carries the manually placed emergency test tube 14 to the first sample placement position a, thereby completing the transportation of the emergency test tube 14 to the first sample placement position a.
At the first sample position a, the mixing assembly 30 picks the test tube 14 conveyed by the automatic sample feeding assembly 10 for mixing operation. Specifically, the mixing assembly 30 includes a gripper, which is located right above the first sample placement position a and moves up and down to grip the test tube 14 conveyed to the first sample placement position a. In one embodiment, the mixing assembly 30 performs mixing operations on the common test tube 14 in a rotating, inverting, or other manner, such that a relatively large amount of venous blood sample can be quickly mixed; the mixing operation of the microtube 14 by high-frequency vibration or the like can quickly and sufficiently mix the peripheral blood sample having a relatively small dose without destroying the cell morphology in the blood. After the blending assembly 30 grabs the test tube 14 conveyed by the automatic sample feeding assembly 10 and blends, the transferring assembly 40 moves forward to enable the second sample seat 42 to reach the first sample placing position a, the gripper places the blended test tube 14 in the second sample seat 42, and the transferring assembly 40 moves backward to convey the second sample seat 42 and the blended test tube 14 to the sample sucking position C for puncture sampling.
When the blending assembly 30 grabs the emergency test tube 14 conveyed by the manual sample feeding assembly 20 at the first sample placing position a, no additional blending operation is usually required because the standing time of the sample in the emergency test tube 14 is short or the user can manually shake the sample before placing the sample. At this time, the first driving member 24 drives the first sliding member 26 to move backward, and in the process, the second sliding member 28 moves in the transverse direction while moving backward under the action of the second guiding section 292, so that the first sample seat 22 is allowed to move out of the first sample position a, and returns to the state shown in fig. 2 to 4; thereafter, the transfer assembly 40 moves forward to the first sample placement position a, the hand grip moves down to place the emergency test tube 14 in the second sample seat 42 of the transfer assembly 40, and then the transfer assembly 40 moves backward to transport the second sample seat 42 and the emergency test tube 14 to the sample aspirating position C for puncture sampling.
The height of the sampling needle of the sampling assembly 50 that descends during the puncture sampling is different according to the types of test tubes, and the height H1 that descends during the puncture sampling of the ordinary test tube 14 is generally larger than the height H2 that descends during the puncture sampling of the micro test tube 14, so that the sampling needle can extend into the bottom of various test tubes 14 to suck enough samples to avoid causing the waste of the samples, and the sampling needle can not only avoid striking the bottom of the test tube 14 to cause the damage of the sampling needle or the test tube 14. The detection assemblies are preferably a plurality of detection assemblies, the detection assemblies are sequentially arranged along the X direction, the sampling needles move along a sample dividing path in the X direction, the sucked samples to be detected are dispensed into the reaction cells of the detection assemblies, and the samples to be detected are mixed with corresponding reagents in the reaction cells and react to obtain final detection results through optical and electrical detection elements.
Fig. 9-13 illustrate a second embodiment of a manual sample injection assembly 20 of a sample analyzer of the present invention, which differs from the first embodiment primarily in the second slide 28 of the manual sample injection assembly 20.
In this embodiment, the second slider 28 includes a first end portion 284, a second end portion 286, and an intermediate connecting portion 285 obliquely connected between the first end portion 284 and the second end portion 286. Wherein, the first end portion 284 and the second end portion 286 extend along the Y direction, the first end portion 284 is movably connected with the first slider 26, and the first sample seat 22 is disposed on the second end portion 286. The inclined intermediate connecting portion 285 offsets the first end portion 284 and the second end portion 286 by a certain distance in the X direction, that is, the second slider 28 itself is structured such that the first sample holder 22 is offset by a certain distance in the X direction with respect to the first slider 26.
The rail 29 includes a first guide section 290 extending along the Y direction and a second guide section 292 extending from the rear end of the first guide section 290 to be inclined backward, and preferably the inclination angle of the second guide section 292 is identical to the inclination angle of the intermediate connecting portion 285 of the second slider 28. The entire track 29 is offset to one side of the transfer module 40 in the X direction, and the first guide section 290 is spaced apart from and parallel to the moving path of the second sample holder 42 of the transfer module 40, and the two are completely staggered without overlapping. Initially, as shown in fig. 11, the second end 286 of the second slider 28 and the first sample holder 22 are in alignment with the first guide segment 290.
As shown in fig. 12, when manual feeding is required, the first driving member 24 drives the first slide 26 to move forward, so that the second slide 28 moves forward along the second guiding section 292 and moves laterally to move the first end portion 284 of the first slide to the first guiding section 290, the second end portion 286, and the first sample holder 22 on the second end portion 286 to the first sample position a, thereby realizing the track change of the first sample holder 22. Thereafter, the first end portion 284 continues to move forward along the first guide section 290 until the first sample holder 22 moves to the second sample position B to receive the manually placed test tube 14.
After the test tube 14 is manually inserted, as shown in fig. 13, the first driving member 24 rotates reversely so that the first end portion 284 of the second sliding member 28 moves backward along the first guiding section 290 until the first specimen holder 22 returns to the first sample placement position a, and the gripper moves downward to grip the emergency test tube 14. Finally, the first driving member 24 drives the first end portion 284 to move along the second guiding section 292 for resetting, so that the second end portion 286 and the first sample holder 22 move to be aligned with the first guiding section 290, thereby avoiding the first sample placement position a, and facilitating the transportation assembly 40 to move to the first sample placement position a for receiving the emergency test tube 14.
The manual sample feeding assembly 20 of the present embodiment, through the structure of the second slide 28, causes the first sample holder 22 and the first slide 26 to be misaligned in the X direction, so that the whole track 29 can be completely misaligned with the transferring assembly 40, and compared to the embodiment shown in fig. 2, the first guide section 290 of the track 29 coincides with the moving path of the transferring assembly 40, which facilitates the arrangement and matching of the components. In the present embodiment, the first slider 26 is a slider, and guides the movement thereof in the Y direction in cooperation with the guide bar 21, and the slide rail structure is omitted. The guide bars 21 may be respectively disposed at left and right sides of the first slider 26 so that the movement of the first slider 26 is more smooth.
Preferably, a supporting portion 288 is disposed below the second sliding member 28, and the supporting portion 288 is spaced from the sliding portion 282 by a certain distance, so as to effectively prevent the side end of the second sliding member 28 from tilting, and make it more stable. The position of support 288 is preferably located at the front side of track 29, and when manual sampling assembly 20 is in initial position D, support 288 is located below second end 286; when the manual sample feeding assembly 20 is in the second sample setting position B, the supporting portion 288 is located at the center of the second sliding member 28, so as to provide good supporting and balancing effects. Preferably, a plurality of balls 289 are disposed in the supporting portion 288, and the balls 289 form rolling friction with the bottom surface of the second sliding member 28, so that the moving resistance of the second sliding member 28 is smaller.
Fig. 14-18 show a third embodiment of a manual feed assembly 20 of a sample analyzer of the present invention, which differs from the first embodiment mainly by the second slide 28 and the track 29 of the manual feed assembly 20.
In this embodiment, the sliding portion 282 of the second sliding member 28 is disposed on a side thereof facing away from the transferring assembly 40, and the rail 29 is a bar structure protruding from the supporting plate 60. The sliding part 282 interacts with the side of the rail 29 facing the transfer assembly 40, that is to say the second slide 28 and the rail 29 come into contact in the X direction. When the second slider 28 and the first sample holder 22 move toward the second sample placement position B, the second guide section 292 of the rail 29 pushes the sliding portion 282 toward the transfer unit 40, so that the second slider 28 and the first sample holder 22 displace in the X direction, thereby realizing the rail change and moving the first sample holder 22 to the first sample placement position a.
An elastic member 70, such as a spring, is connected between the second slider 28 and the first slider 26. The elastic member 70 is disposed along the X direction, and when the manual sample feeding assembly 20 is in the initial position D, the elastic member 70 is naturally extended. When the second slide 28 moves along the second guide segment 292 to the first sample position a, the second slide 28 displaces relative to the first slide 26 in the X direction, so that the elastic member 70 is stretched and deformed. When the second sliding member 28 moves along the first guide segment 290 between the first sample position a and the second sample position B, the elastic member 70 is kept in a stretched state so that the sliding portion 282 moves against the first guide segment 290. When the second sliding member 28 moves backward along the second guiding section 292 to return to the original position, the elastic member 70 recovers its shape and pulls the second sliding member 28 to move backward along the X direction, so that the sliding portion 282 moves against the second guiding section 292 to ensure smooth movement of the second sliding member 28.
Fig. 19-23 illustrate a fourth embodiment of a manual sample feeding assembly 20 of a sample analyzer of the present invention, wherein the second slide 28 and the track 29 are arranged similarly to the second embodiment, the second slide 28 is composed of a first end portion 284, a second end portion 286, and an intermediate connecting portion 285 connecting the first end portion 284 and the second end portion 286 by bending; the rail 29 includes a first guide section 290 extending along the Y direction and a second guide section 292 inclined with respect to the Y direction. The track 29 is completely offset from the transfer module 40, the second end 286 of the second slide 28 and the first sample holder 22 are aligned with the first guide section 290, and the first guide section 290 is spaced parallel to the path of travel of the transfer module 40.
In the present embodiment, the rail 29 is a bar structure protruding from the supporting plate 60, and the sliding portion 282 of the second sliding member 28 is disposed on a side thereof facing away from the transferring assembly 40 and interacts with a side of the rail 29 facing toward the transferring assembly 40. The elastic member 70 is connected between the first end 284 of the second slider 28 and the first slider 26, and when the manual sample feeding assembly 20 is in the initial position D, the elastic member 70 is naturally extended; when the second slide 28 moves along the second guide segment 292 to the first sample position a, the second slide 28 displaces relative to the first slide 26 in the X direction, so that the elastic member 70 is stretched and deformed. When the second slider 28 moves backward along the second guide section 292 to be restored, the elastic member 70 is deformed again to pull the second slider 28 in the X direction so that the sliding portion 282 thereof can move close to the rail 29, which is similar to the third embodiment.
Fig. 24-28 show a fifth embodiment of a manual sample feeding assembly 20 of a sample analyzer according to the present invention, which is different from the fourth embodiment mainly in that: the sliding portion 282 of the second slide 28 is disposed on the side thereof facing the transfer unit 40, and interacts with the side of the rail 29 facing away from the transfer unit 40, and the sliding portion 282 and the rail 29 are likewise brought into contact in the X direction. An elastic member 70, preferably a coil spring, is also disposed between the first end 284 of the second slider 28 and the first slider 26, and the elastic member 70 is disposed around the shaft 72 and sandwiched between the first end 284 and the first slider 26. The shaft 72 is disposed along the X direction, one end of the shaft is fixedly connected to the first sliding member 26, and the other end of the shaft is movably inserted into the first end 284, so that the elastic member 70 deforms to enable the second sliding member 28 to slide along the shaft 72 in the X direction, thereby guiding the movement of the second sliding member 28 in the X direction.
In the initial state, the elastic member 70 is in a compression deformation state. In the manual sample feeding mode, the second slider 28 moves forward along the track 29, the second guide section 292 enables the second slider 28 to displace in the X direction and move away from the first slider 26, the elastic element 70 compressed in this way restores to deform, so that the sliding portion 282 can move close to the second guide section 292, and the first sample seat 22 can displace in the X direction to reach the first sample placing position a; the elastic member 70 abuts against the second sliding member 28 to move along the first guiding section 290, so as to push the first sample holder 22 to the second sample position B for manual insertion of the test tube 14. When the second slider 28 moves backward to return to and passes through the second guide section 292, the elastic member 70 is compressed again due to the displacement of the second slider 28 in the X direction, and the entire automatic sample introduction assembly 10 returns to the initial state.
The automatic sample feeding assembly 10 and the manual sample feeding assembly 20 are arranged to respectively move the automatically conveyed test tube 14 and the manually placed emergency test tube 14 to the first sample placing position A, the first sample seat 22 of the manual sample feeding assembly 20 and the second sample seat 42 of the transfer assembly 40 are staggered with each other in an initial state, the first sample seat 22 moves among the second sample placing position B, the first sample placing position A and the initial position D, wherein the path along the Y direction moves between the second sample placing position B and the first sample placing position A to realize sample feeding of the emergency test tube 14, the bent path moves between the first sample placing position A and the initial position D to avoid the second sample seat 42, the movement of the first sample seat 22 in the X, Y two directions can be realized by designing a single driving piece through rail change without a complex transmission mechanism, the structure is simple and the operation is convenient on the whole, and the automatic sample feeding assembly 10, the emergency test tube 14 and the emergency test tube 14 placed manually can be better coordinated, The operation of manual appearance subassembly 20, transport subassembly 40 etc. the user can start manual appearance subassembly 20 and come to put into emergency call test tube 14 and detect, has avoided the contaminated risk of emergency call sample, also can realize the quick transportation of emergency call sample through this structure, reduces patient's latency.
It should be noted that the present invention is not limited to the above-mentioned embodiments, and other changes and modifications can be made by those skilled in the art according to the spirit of the present invention, and these changes and modifications made according to the spirit of the present invention should be included in the scope of the present invention as claimed.

Claims (9)

1. A manual sample feeding assembly is applied to a sample analyzer and used for conveying a tube to be tested to a first sample placing position, and is characterized by comprising a first sample seat, a first driving piece for driving the first sample seat to move, a first sliding piece, a second sliding piece and a track for guiding the first sample seat to move, wherein the first sample seat is provided with a sample placing position for placing a test tube, the track comprises a first guide section extending along the Y direction and a second guide section obliquely arranged relative to the first guide section, the first sample seat moves between the first sample placing position and the second sample placing position under the action of the first guide section and moves between the first sample placing position and an initial position under the action of the second guide section, and the first sample seat is offset to one side of a connecting line of the first sample placing position and the second sample placing position in the initial position; the first driving piece is connected with the first sliding piece and drives the first sliding piece to move along the Y direction, one end of the second sliding piece is movably connected with the first sliding piece and can move relatively in the X direction, and the other end of the second sliding piece is provided with the first sample seat, so that the first driving piece can drive the first sample seat to move along the second guide section in X, Y two directions; the second sliding part is bent, and the second guide section deviates from a connecting line of the first sample placing position and the second sample placing position in the X direction by a certain distance.
2. The manual sample feeding assembly of claim 1, wherein the second slider includes a first end portion, a second end portion, and an intermediate connecting portion obliquely connected between the first end portion and the second end portion, the first end portion and the second end portion are staggered in the X direction, the first end portion is connected with the first slider, and the first sample holder is disposed at the second end portion.
3. The manual feed assembly of claim 2, wherein an inclination angle of the second guide section is consistent with an inclination angle of the intermediate connection portion of the second slider.
4. The manual sample feeding assembly according to claim 1, wherein the rail has a groove structure, and a bottom of an end of the second sliding member connected to the first sliding member is provided with a sliding portion at least partially embedded in the rail; or the rail is of a protruding barrier strip structure, a sliding part is arranged on the side face of one end, connected with the first sliding part, of the second sliding part, and the sliding part abuts against the side face of the rail.
5. The manual sample feeding assembly according to claim 4, wherein a support portion is disposed below the second sliding member, the support portion and the sliding portion are spaced apart from each other, and a ball is disposed in the support portion and forms rolling friction with the second sliding member.
6. The manual sample introduction assembly of claim 1, wherein an elastic member is disposed between the first sliding member and the second sliding member.
7. A sample analyzer is characterized by comprising an automatic sample feeding assembly and a manual sample feeding assembly, wherein the automatic sample feeding assembly conveys a test tube rack loaded with a tube to be tested to a first sample placing position along an automatic sample feeding path in the X direction, and the manual sample feeding assembly is the manual sample feeding assembly according to any one of claims 1 to 6.
8. The sample analyzer of claim 7 further comprising a transport assembly that moves along a transport path in the Y-direction between a first sample position and a draw position, the second sample position, the first sample position, and the draw position being arranged sequentially in the Y-direction.
9. The sample analyzer of claim 8 further comprising a plurality of sampling assemblies and a plurality of detection assemblies, wherein the plurality of detection assemblies are arranged along the X-direction, the sampling assemblies move along the sample splitting path along the X-direction between the sample suction position and a plurality of sample splitting positions, and each sample splitting position corresponds to one of the detection assemblies.
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