CN214794844U

CN214794844U - Full-automatic chemiluminescence immunoassay analyzer

Info

Publication number: CN214794844U
Application number: CN202120897653.XU
Authority: CN
Inventors: 刘佳佳; 王丽君
Original assignee: Suzhou Zundao Biotechnology Co ltd
Current assignee: Suzhou Zundao Biotechnology Co ltd
Priority date: 2021-04-28
Filing date: 2021-04-28
Publication date: 2021-11-19
Anticipated expiration: 2031-04-28

Abstract

A fully automated chemiluminescent immunoassay analyzer comprising: a machine platform; a reagent strip module; a tip module configured to aspirate a sample to the reagent strip module and mix a reagent and magnetic beads in the reagent strip module with the sample; the puncture liquid-separating module is configured to puncture a sealing film of the reagent strip module to realize the separate injection of the cleaning liquid and the substrate liquid; the incubation and cleaning module is configured to perform temperature control treatment on the reagent strip module, and extract and clean the mixture coated by the magnetic beads in the reagent strip module by using a magnetic rod; a measurement module configured to read the reagent strip module; wherein, the reagent strip module includes at least two sets of reagent strip units, incubates the washing module including incubating the unit and extracting and abluent washing separating element to the mixture of reagent strip unit, incubates the unit including the base of incubating, and the heating member of setting on incubating the base that is used for placing every group of reagent strip unit. The device realizes full automation, convenience and rapidness.

Description

Full-automatic chemiluminescence immunoassay analyzer

[ technical field ] A method for producing a semiconductor device

The utility model relates to a full-automatic chemiluminescence immunoassay appearance belongs to medical instrument technical field.

[ background of the invention ]

The enzyme-catalyzed luminescence immunoassay technology is characterized in that an enzyme-labeled antibody (or antigen) is used for reacting to form a solid-phase coated antibody-antigen to be detected-enzyme-labeled antibody compound, luminol, isoluminol or AMPPD and other luminescent agents are added, the substrate is broken through enzyme-catalyzed reaction to generate chemiluminescence, and the enzyme-catalyzed reaction can last for 15-60min stably, so that the process of emitting photons is stable and high in reliability.

Based on the characteristics of longer enzymatic luminescence duration and stability and reliability, a plurality of single-reagent-type POCT analyzers emerge in the market in recent years, namely, reagents, cleaning liquid and substrates required by single detection are all packaged in one reagent strip, an operator manually adds samples into a sample position specified by the reagent strip in a quantitative mode, the reagent strip is inserted into an instrument and then the instrument executes a subsequent detection process, the single instrument can support 6-10 reagent strips to detect simultaneously, compared with large-scale equipment in an inspection department, the single-reagent-type POCT analyzer has the advantages of being small and exquisite and portable, compared with a multi-reagent kit in single-reagent packaging, the single-reagent-type POCT analyzer can prevent cross contamination and bottle opening volatilization, and a liquid-free path system in the instrument reduces the using environment requirements of the instrument. However, the instruments in the market currently have the following drawbacks: the operation is complicated, and the detection and analysis process is interfered by manpower, so that the biological pollution is easily caused.

Accordingly, there is a need for improvements in the art that overcome the deficiencies in the prior art.

[ Utility model ] content

An object of the utility model is to provide a full-automatic chemiluminescence immunoassay appearance, operation process does not have artificial intervention and realizes the full automatization, and convenient and fast has improved the degree of accuracy of analysis by detection simultaneously.

The utility model aims at realizing through the following technical scheme: a fully automated chemiluminescent immunoassay analyzer comprising:

a machine platform;

the reagent strip module is arranged on the machine table;

the sucker module is arranged on the machine table and can move relative to the reagent strip module; the tip module is configured to aspirate a sample to the reagent strip module and mix reagents and magnetic beads within the reagent strip module with the sample;

the puncture liquid-separating module is arranged on the machine table and can move relative to the reagent strip module; the puncture liquid-separating module is configured to puncture a sealing film of the reagent strip module to realize the separate injection of a cleaning solution and a substrate solution;

the incubation and cleaning module is arranged on the machine table and can move relative to the reagent strip module; the incubation and cleaning module is configured to perform temperature control treatment on the reagent strip module, and perform extraction and cleaning treatment on the mixture coated by the magnetic beads in the reagent strip module by using a magnetic rod;

The measuring module is arranged on the machine table and can move relative to the reagent strip module; the measurement module is configured to read the reagent strip module;

wherein, the reagent strip module includes at least two sets of reagent strip units, it is right to incubate washing module includes that the reagent strip unit carries out temperature control's incubation unit and right the mixture of reagent strip unit is drawed and abluent washing isolating unit, it includes and is used for placing every group to incubate the base and set up that reagent strip unit and cavity set up and be in heat piece on the incubation base, it is right that the heat piece is used for incubating the base and heating.

In one embodiment, the incubation unit further comprises a temperature control plate disposed on the incubation base, and a temperature control protection switch, wherein the temperature control plate is used for controlling the temperature of the incubation base, and the temperature control protection switch is used for disconnecting the incubation base when the temperature control plate is electrically short-circuited and the incubation base is excessively hot.

In one embodiment, the cleaning and separating unit comprises a frame body, a magnetic rod motor arranged on the frame body, a magnetic rod connected with the magnetic rod motor, a magnetic rod reset optical coupler used for detecting whether the magnetic rod is reset or not, and a magnetic sleeve motor arranged on one side of the magnetic rod motor.

In one embodiment, a first sliding rail is arranged on one of the machine table and the incubation base, and a sliding groove in sliding fit with the first sliding rail is arranged on the other of the machine table and the incubation base; the incubation and cleaning module further comprises a reagent strip driving assembly used for driving the reagent strip unit to move, and the reagent strip driving assembly is arranged on one side of the first sliding rail.

In one embodiment, the suction head module comprises a suction head unit and a suction head driving unit connected with the suction head unit, wherein the suction head driving unit is used for driving the suction head unit to move along a first direction, a second direction and a third direction, and the first direction, the second direction and the third direction are perpendicular to each other.

In one embodiment, the suction head unit comprises a suction head body for sucking, and an air pump connected with the suction head body and used for generating negative pressure.

In one embodiment, the suction head module further comprises a supporting seat erected on the machine table, and the suction head driving unit is arranged on the supporting seat; the suction head driving unit comprises a first suction head driving assembly, a second suction head driving assembly and a third suction head driving assembly, and the third suction head driving assembly is connected with the suction head unit.

In one embodiment, the piercing liquid-separating module comprises a base plate connected with the machine table, a piercing needle driving unit arranged on the base plate, and a piercing unit connected with the piercing needle driving unit.

In one embodiment, the puncture unit comprises a puncture needle body and a code scanner connected with the puncture needle body; the puncture needle driving unit comprises a first puncture driving component and a second puncture driving component, wherein the first puncture driving component is used for driving the puncture unit to move along a first direction, and the second puncture driving component moves along a third direction.

In one embodiment, the full-automatic chemiluminescence immunoassay analyzer further comprises a tip loading module, wherein the tip loading module is arranged above the reagent strip module so as to be in butt joint with the tip module.

Compared with the prior art, the utility model discloses following beneficial effect has: the suction head module, the puncture liquid-separating module and the incubation cleaning module are arranged independently, so that a sample is mixed with a reagent and magnetic beads in the reagent strip module by the suction head module, the puncture liquid-separating module punctures the reagent strip module and adds cleaning liquid and substrate liquid, and the like, and the incubation cleaning module extracts and cleans the mixture coated by the magnetic beads in the reagent strip module by a magnetic rod, so that the sample and the substrate are not polluted, and the operation is convenient and rapid; meanwhile, the suction head module, the piercing liquid-separating module, the incubation cleaning module and the measuring module do not need manual intervention in the operation process, so that full automation is realized, and the detection accuracy is improved;

Be provided with the heating member on incubating the washing module, this heating member heats so that the reagent strip body can be fully reacted under the environment of settlement temperature to the base of incubating, convenient and fast.

[ description of the drawings ]

Fig. 1 is a schematic structural diagram of the full-automatic chemiluminescence immunoassay analyzer of the present invention.

FIG. 2 is a schematic cross-sectional view of the reagent strip unit of FIG. 1.

Fig. 3 is a schematic view of the structure of the tip module of fig. 1.

Fig. 4 is a schematic structural view of the punctured liquid separation module in fig. 1.

Fig. 5 is a schematic structural diagram of the measurement module in fig. 1.

Figure 6 is a schematic diagram of the tip loading module of figure 1.

FIG. 7 is a schematic diagram of the structure of the incubation and washing module in FIG. 1.

[ detailed description ] embodiments

In order to make the above objects, features and advantages of the present invention more comprehensible, embodiments of the present invention are described in detail below with reference to the accompanying drawings. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

The terms "comprising" and "having," as well as any variations thereof, in the present application are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the invention. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.

Referring to fig. 1 to 7, a fully automatic chemiluminescence immunoassay analyzer according to a preferred embodiment of the invention comprises: platform 1, set up reagent strip module 2, suction head module 3 on platform 1, puncture and divide liquid module 4, hatch washing module 9 and measuring module 5, wherein, suction head module 3, puncture and divide liquid module 4, hatch washing module 9 and measuring module 5 all can move for reagent strip module 2 to carry out corresponding operation to reagent strip module 2.

Specifically, the reagent strip module 2 comprises at least two groups of reagent strip units, and when one group of reagent strip units completes separate injection and mixing reaction and moves to the incubation cleaning module 9 and the measurement module 5, the suction head module 3 and the puncture liquid distribution module 4 can perform separate injection and mixing reaction operation on the next group of reagent strip units, so as to improve the detection and analysis efficiency.

Each group of reagent strip units comprises a reagent strip body 21 and a handle 22 connected with the reagent strip body 21, and the handle 22 is used for facilitating a user to hold and place the reagent strip units in the incubation cleaning module 9. The reagent strip body 21 is provided with a cleaning position 211, a reaction position 212, a measurement position 213, a packaging position 214 and a cleaning hole 215 of the lancet body of the lancet module, and the cleaning position 211, the reaction position 212, the measurement position 213, the packaging position 214 and the cleaning hole 215 are sequentially arranged along the transverse length direction of the reagent strip body 21. In this embodiment, three washing sites 211 are provided to extract and wash the mixture coated with magnetic beads sufficiently. Indeed, in other embodiments, the number of the cleaning bits 211 may be other, and is not limited herein, depending on the actual situation.

Encapsulation position 214 is including the first hole that is used for placing the substrate, the second hole of placing the magnetic bead and the third hole that is used for placing the enzyme-labeled reagent, and first hole, second hole, third hole are arranged in proper order, and first hole and second hole, third hole top are provided with the packaging film to prevent that downthehole article from leaking. In this embodiment, the packaging film is an aluminum foil composite film, which can be sealed and can be punctured by the puncture needle body or the tip body 322. Similarly, since the cleaning liquid is placed in the cleaning hole 215, a packaging film is also provided in the cleaning hole 215, and this packaging film is the same as described above. In contrast, since the wash site 211, the reaction site 212, and the measurement site 213 are not packaged with any reagent in the initial state of the reagent strip body 21, no packaging film is provided.

Cleaning aperture 215 includes washing liquid encapsulation hole 2151 and puncture needle body cleaning aperture 2152 that sets up in washing liquid encapsulation hole 2151, and in the direction of height of reagent strip body 21, puncture needle body cleaning aperture 2152's height is less than washing liquid encapsulation hole 2151's height, and the purpose that sets up like this is: when the lancet body is transferred to the lancet body cleaning hole 2152, the cleaning liquid is discharged at a certain pressure and flow rate to clean the inner wall of the lancet body 421, and the discharged cleaning liquid performs vortex motion in the lancet body cleaning hole 2152 to clean the outer wall of the lancet body 421. It is noted that the height of the cleaning fluid within piercing needle body cleaning bore 2152 is less than the height of the bore. In order to prevent the eddy motion failure, the present embodiment is implemented by quantitatively packaging and filling the cleaning solution.

The reagent strip unit also includes a magnetic cover 216 pre-installed on one side of the handle, i.e., the magnetic cover 216 is pre-installed between the handle and the cleaning aperture 215.

The incubation washing module 9 is configured to perform temperature control processing on the reagent strip module 2, and extract and wash the mixture coated with the magnetic beads in the reagent strip module 2 with the magnetic sleeve 216. Incubate washing module 9 including to the reagent strip unit carry out temperature control incubate unit 91 and to the mixture of reagent strip unit extract and abluent washing separating unit 92, incubate unit 91 be used for placing the base 911, the setting of incubating of every group reagent strip unit and cavity setting of incubating the base 911, set up the reagent strip body 21 in incubating the base 911, set up the heating member 913 on incubating the base 911, heating member 913 is used for heating incubation base 911. Since the reagent strip body 21 is generally stored in cold air, the reaction temperature of the reagent strip body 21 is preferably 37 ℃. After the incubation base 911 is heated, the reagent strip body 21 is gradually heated to the reaction temperature in a certain temperature environment, which is convenient and fast. In this embodiment, the heating element 913 is a heating film that covers at least a portion of the incubation base 911. Indeed, in other embodiments, the heating element 913 may be other elements, and is not limited herein, as the case may be. In the embodiment, the heating film is fixedly disposed at the bottom of the incubation base 911, so as to ensure uniformity of the temperature field of the incubation base 911.

The incubation unit 91 further comprises a temperature control plate 912 disposed on the incubation base 911, and a temperature control protection switch 914, wherein the temperature control plate 912 is used for controlling the temperature of the incubation base 911, and the temperature control protection switch 914 is used for disconnecting the incubation base 911 when the temperature control plate 912 is electrically shorted. Wherein, the temperature control plate 912 is arranged on the side wall of the incubation base 911. As described above, since the optimal reaction temperature of the reagent strip body 21 is 37 ℃, the temperature control plate 912 precisely controls the incubation temperature to be 37 〒 0.5.5 ℃. Correspondingly, a temperature-controlled protection switch 914 is disposed on the sidewall of the incubation base 911 and is disposed close to the temperature-controlled board 912.

Each group of reagent strip units can move along the Y-axis direction of the machine 1, so in this embodiment, one of the machine 1 and the incubation base 911 is provided with a first slide rail, and the other of the machine 1 and the incubation base 911 is provided with a slide groove in sliding fit with the first slide rail. Correspondingly, the incubation and washing module 9 further comprises a reagent strip driving assembly 915 for driving the reagent strip unit to move, and the reagent strip driving assembly 915 is arranged on one side of the first sliding rail. In this embodiment, the reagent strip driving unit is a driving motor.

Incubation unit 91 is still including setting up the opto-coupler that resets at first slide rail opposite side, and this opto-coupler that resets is used for detecting whether reagent strip unit resets.

Wash the disengaging unit 92 and include the support body, set up bar magnet motor 921 on the support body, with bar magnet that bar magnet motor 921 is connected, be used for detecting whether the bar magnet that the bar magnet resets opto-coupler and setting are in the magnetic sleeve motor 922 of bar magnet motor 921 one side, magnetic sleeve motor 922 and bar magnet motor 921 can drive the bar magnet and reciprocate along the Z axle. The magnetic sleeve motor 922 and the magnetic rod motor 921 move downwards to extend the magnetic rod, move to the position of the magnetic sleeve 216 to attract the magnetic sleeve 216 and the magnetic rod, move the cleaning position 211 to attract the magnetic beads, obtain a mixture coated by the magnetic beads, clean and extract the mixture coated by the magnetic beads, finally transfer the mixture from the magnetic sleeve 216 to the measurement position 213, stably emit sustainable light with a wavelength of 470nm after the mixture of the magnetic beads and a substrate added in advance fully react, and finally convert, measure and read by the measurement unit.

The suction head module 3 comprises a suction head unit 32 and a suction head driving unit 31 connected with the suction head unit 32, wherein the suction head driving unit 31 is used for driving the suction head unit 32 to move along a first direction, a second direction and a third direction, and the first direction, the second direction and the third direction are mutually perpendicular. In this embodiment, the first direction is an X-axis direction, the second direction is a Y-axis direction, and the third direction is a Z-axis direction. Indeed, in other embodiments, the first direction, the second direction and the third direction may have other indications, which are not specifically limited herein, according to the actual situation. Specifically, the nozzle driving unit 31 includes a first nozzle driving assembly 311, a second nozzle driving assembly 312, and a third nozzle driving assembly 313, and the third nozzle driving assembly 313 is connected to the nozzle unit 32. In this embodiment, the first pipette head driving assembly 311, the second pipette head driving assembly 312, the third pipette head driving assembly 313 and the reagent strip driving assembly are the same driving motors, and the first pipette head driving assembly 311, the second pipette head driving assembly 312 and the third pipette head driving assembly 313 can drive the pipette head unit 32 to move through chain transmission, which is a conventional structure and will not be described herein.

The suction head unit 32 includes a suction head body 322 for sucking, and an air pump 321 connected to the suction head body 322 for generating negative pressure, wherein the suction head body 322 is in butt joint with a pump body of the air pump 321. The air pump 321 can automatically load and unload the suction head, determine whether the suction head is in place or unloaded, quantitatively discharge liquid, and detect the liquid level. The tip driving unit 31 drives the tip body 322 to move to the sample site to aspirate the sample and place the sample in the reaction site 212. Wherein the air pump 321 is connected to the third tip drive assembly 313. The suction head module 3 further comprises a support base erected on the machine table 1, and the suction head driving unit 31 is arranged on the support base. In the present embodiment, the tip driving unit 31 is disposed above the reagent strip module 2, and operates the reagent strip module 2. The tip body 322 is typically a plastic material that can easily puncture the packaging film. Indeed, in other embodiments, the material of the suction head body 322 may be other, as long as the above-mentioned effects are achieved, and is not specifically limited herein, depending on the actual situation.

The tip driving unit 31 drives the tip unit 32 to move to add the sample into the reaction site 212, and the tip moves down to puncture the packaging film, and enters the second hole and the third hole to absorb and add the magnetic beads and the enzyme-labeled reagent into the reaction site 212, so as to form a mixture coated by the magnetic beads in the reaction site 212.

The puncture and liquid separation module 4 is configured to puncture the sealing film of the reagent strip module 2 to achieve dispensing of the cleaning solution and the substrate solution. The puncture liquid-separating module 4 comprises a base plate connected with the machine table 1, a puncture needle driving unit 41 arranged on the base plate, and a puncture unit 42 connected with the puncture needle driving unit 41. In this embodiment, the height of the substrate is lower than that of the supporting base, i.e. the piercing liquid-separating module 4 is located below the sucker module 3. The puncturing unit 42 includes a puncturing needle body 421 and a code scanner 422 connected to the puncturing needle body 421, wherein the puncturing needle body 421 is used to puncture the packaging film to fill the cleaning solution and the substrate quantitatively packaged in the reagent strip to the cleaning position 211 and the measuring position 213 on the reagent strip body 21. The bar code scanner 422 reads the bar code on each reagent strip unit to record that the reagent strip unit has been dispensed.

It should be noted that, in order to prevent the contamination, in this embodiment, before the substrate is sucked, the puncture needle body 421 needs to be cleaned, which includes the following steps: the puncture needle body 421 sucks a certain amount of cleaning solution, sucks a section of air column, and then sucks a certain amount of substrate before sucking the substrate after the cleaning solution is filled.

Lancet driving unit 41 includes a first lancing driving element 411 for driving lancing unit 42 to move along a first direction, and a second lancing driving element 412 for moving along a third direction, as described above, in this embodiment, the first direction is an X-axis direction, the third direction is a Z-axis direction, and first lancing driving element 411 and second lancing driving element 412 are identical to the above, and are both driving motors, and the coupling of the two is realized by chain rotation, which is a conventional structure, and will not be described herein.

The measurement module 5 is configured to read the reagent strip module 2. The measuring module 5 includes a measuring base plate 51 disposed on the machine platform 1, a cassette 52, a photomultiplier tube 53 connected to the cassette 52, a first measuring driving component 54 for driving the photomultiplier tube 53 to move along the z-axis, and a second measuring driving component 55 disposed on the measuring base plate 51 for driving the photomultiplier tube 53 to move along the X-axis. When the incubation base 911 drives the reagent strip body 21 to move along the first slide rail to the position right below the cassette 52, the first measurement driving assembly 54 drives the cassette 52 to descend and press the reagent strip body 21, and at this time, the photomultiplier 53 is opened to start measurement and reading.

The full-automatic chemiluminescence immunoassay analyzer also comprises a sucker loading module 7, and the sucker loading module 7 is arranged above the reagent strip module 2 to be in butt joint with the sucker module 3. The tip loading module 7 is mainly used for storing disposable tips, and can prevent cross contamination among different projects. The suction head loading module 7 comprises a suction head box bottom plate 61 arranged on the machine table 1, a second slide rail 62 arranged on the suction head box bottom plate 61, a suction head box seat 64 which is in sliding fit with the second slide rail 62 and is used for placing the suction head body 322, a positioning bearing 63 arranged on one side of the second slide rail 62, and a support plate 65 which is arranged on the suction head box bottom plate 61 and is opposite to the suction head box seat 64, wherein a sensor 66 for detecting whether the suction head box seat 64 is in place is arranged on the support plate 65, so that the suction head body 322 is ensured to be loaded smoothly. The support plate 65 is further provided with a magnet 67, and correspondingly, the suction head box base 64 is provided with a magnetic part matched with the magnet 67, or the suction head box base 64 is made of magnetically attractable metal, and is not particularly limited and is determined according to actual conditions.

When the suction head body 322 needs to be replaced, the suction head box seat 64 is pulled out, and when the suction head box seat 64 is pushed back after replacement is completed, the suction head box seat can be automatically positioned in the X-axis direction under the action of the four positioning bearings 63, and the positioning and fixing in the Y-axis direction can be completed through the magnets 67 fixed on the support plate 65.

The full-automatic chemiluminescence immunoassay analyzer also comprises a waste collection module 8 for collecting the waste sucker body 322 and a sample loading module 7 for placing a sample, wherein the waste collection module 8 is a waste box 8, and the sample loading module 7 is arranged on the waste box 8. The sample loading module 7 includes a sample rack 72 and a test tube 71 placed in the sample rack 72, and the sample is stored in the test tube 71. The sample loading module 7 further comprises a limiting strip arranged on the waste box 8, a guide pin arranged on one side of the limiting strip, a positioning plunger used for positioning the sample frame body 72 and an in-place sensor used for detecting whether the sample frame body 72 is in place or not, the sample frame body 72 can slide along the guide pin and the limiting strip, a blanking channel is arranged on the positioning plunger, and the blanking channel is communicated with the waste box.

The utility model discloses holistic action flow is as follows: after the sample and the reagent strip body 21 are loaded, the sucker module 3 is loaded with a disposable sucker, the sample, the enzyme labeling reagent and the magnetic beads are respectively and quantitatively added into the reaction position 212 of the reagent strip body 21 to form a mixture coated by the magnetic beads, the mixture in the reagent strip body 21 is fully reacted at 37 ℃ of the incubation unit 91, the puncture needle body 421 on the liquid separation module 4 is punctured in the incubation process to pre-add the cleaning liquid and the substrate which are quantitatively packaged in the reagent strip body 21 into the cleaning position 211 and the measurement position 213 corresponding to the reagent strip body 21, the incubation unit 91 moves to the cleaning position 211 after the incubation is finished, the mixture coated by the magnetic beads is extracted and cleaned by the magnetic sleeve motor 922 and the magnetic rod motor 921, and finally the mixture is transferred to the measurement position 213 by the magnetic sleeve 216, and the sustainable light with the wavelength of 470nm is stably emitted after the mixture and the pre-added substrate are fully reacted, and finally, the measurement module 5 converts the measurement and reading. During incubation and cleaning, the suction head module 3 can continuously sample for the next item, so except that the suction head module 3 is in serial action, other action flows are in parallel action and do not interfere with each other.

In summary, the following steps: the sucker module 3, the puncture liquid-separating module 4 and the incubation cleaning module 9 are independently arranged, so that a sample is mixed with a reagent and magnetic beads in the reagent strip module 2 by the sucker module 3, the puncture liquid-separating module 4 punctures the reagent strip module 2 to add cleaning liquid and the like, and the magnetic sleeve 216 of the reagent strip module 2 is sucked by the incubation cleaning module 9 to extract and clean a mixture coated by the magnetic beads, so that the sample and a substrate are not polluted, and the operation is convenient and rapid; meanwhile, the suction head module 3, the puncture liquid-separating module 4, the incubation cleaning module 9 and the measuring module 5 do not need manual intervention in the operation process, so that full automation is realized, and the detection accuracy is improved;

be provided with heating member 913 in hatching washing module 9 module, this heating member 913 heats so that reagent strip body 21 can fully react under the environment of set temperature to hatching base 911, convenient and fast.

The above is only a specific embodiment of the present invention, and other improvements made on the premise of the inventive concept are all considered as the protection scope of the present invention.

Claims

1. A full-automatic chemiluminescence immunoassay analyzer is characterized by comprising:

A machine platform;

the reagent strip module is arranged on the machine table;

2. The fully automated chemiluminescent immunoassay analyzer of claim 1 wherein the incubation unit further comprises a temperature control board disposed on the incubation base, the temperature control board being configured to control the temperature of the incubation base, and a temperature control protection switch configured to switch off the incubation base when the temperature control board is electrically shorted.

3. The full-automatic chemiluminescence immunoassay analyzer of claim 1, wherein the cleaning and separating unit comprises a frame body, a magnetic bar motor arranged on the frame body, a magnetic bar connected with the magnetic bar motor, a magnetic bar reset optical coupler for detecting whether the magnetic bar is reset or not, and a magnetic sleeve motor arranged on one side of the magnetic bar motor.

4. The full-automatic chemiluminescence immunoassay analyzer of claim 1, wherein one of the machine platform and the incubation base is provided with a first slide rail, and the other of the machine platform and the incubation base is provided with a slide groove in sliding fit with the first slide rail; the incubation and cleaning module further comprises a reagent strip driving assembly used for driving the reagent strip unit to move, and the reagent strip driving assembly is arranged on one side of the first sliding rail.

5. The full-automatic chemiluminescence immunoassay analyzer of claim 1, wherein the tip module comprises a tip unit and a tip driving unit connected to the tip unit, wherein the tip driving unit is configured to drive the tip unit to move in a first direction, a second direction and a third direction, and the first direction, the second direction and the third direction are perpendicular to each other.

6. The full-automatic chemiluminescence immunoassay analyzer of claim 5, wherein the tip unit comprises a tip body for sucking, and an air pump connected to the tip body for generating negative pressure.

7. The full-automatic chemiluminescence immunoassay analyzer of claim 5, wherein the tip module further comprises a support base erected on the machine base, the tip driving unit being disposed on the support base; the suction head driving unit comprises a first suction head driving assembly, a second suction head driving assembly and a third suction head driving assembly, and the third suction head driving assembly is connected with the suction head unit.

8. The full-automatic chemiluminescence immunoassay analyzer of claim 1, wherein the puncture liquid separating module comprises a substrate connected with the machine platform, a puncture needle driving unit arranged on the substrate, and a puncture unit connected with the puncture needle driving unit.

9. The fully-automatic chemiluminescent immunoassay analyzer of claim 8 wherein the lancing unit comprises a lancet body and a code scanner connected to the lancet body; the puncture needle driving unit comprises a first puncture driving component and a second puncture driving component, wherein the first puncture driving component is used for driving the puncture unit to move along a first direction, and the second puncture driving component moves along a third direction.

10. The fully automated chemiluminescent immunoassay analyzer of claim 1 further comprising a tip loading module disposed above the reagent strip module to interface with the tip module.