CN215963630U - Blood collection container for separating platelet-rich fibrin - Google Patents
Blood collection container for separating platelet-rich fibrin Download PDFInfo
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- CN215963630U CN215963630U CN202121170767.0U CN202121170767U CN215963630U CN 215963630 U CN215963630 U CN 215963630U CN 202121170767 U CN202121170767 U CN 202121170767U CN 215963630 U CN215963630 U CN 215963630U
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Abstract
The invention relates to the technical field of medical instruments, in particular to a blood collection container for separating platelet-rich fibrin, which comprises an outer tube, wherein the top of the outer tube is provided with a safety cap, the bottom of the outer tube is provided with a base, and an inner tube is inserted into the outer tube; the inner tube includes body and lower body, and the bottom outer wall integrated into one piece of body has last cone, and the top outer wall integrated into one piece of body has down the cone down, and integrated into one piece has the connecting pipe between last cone and the lower cone, is formed with the water storage chamber between inner tube and the outer tube naturally, and the bottom inner wall of outer tube is provided with at the bottom of the circular arc, and the bottom outer wall of inner tube is provided with at the bottom of the sphere, and the bottom outer wall integrated into one piece of outer tube has the connecting neck. The inner tube is made into a structure that the diameter of the upper tube body and the diameter of the lower tube body are larger than that of the connecting tube, so that plasma rich in platelets and fibrin can be separated at one time when blood is centrifuged, and the extraction of the plasma rich in platelets is more convenient.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a blood collection container for separating platelet-rich fibrin.
Background
Normal biological tissues have certain self-repairing capacity and are mainly realized by growth factors, and human blood is rich in a large amount of growth factors. The blood consists of cell components such as visible components including red blood cells, white blood cells, platelets and the like and liquid components, the blood can be separated to extract high-concentration platelets, white blood cells and fibrin from whole blood, the platelets can secrete a plurality of growth factors after being activated, the white blood cells can prevent infection, and the fibrin can locally construct a three-dimensional structure required by tissue repair. High-concentration growth factors, fibrin and leukocytes with biological activity separated from autologous blood can be used in a plurality of medical fields such as wound repair, medical cosmetology, oral and maxillofacial surgery, plastic surgery, fracture healing and the like, and in recent years, research results for extracting human autologous growth factors for regenerative medicine and medical instrument products are mostly concentrated on extracting platelet-rich plasma.
Chinese patent No. CN201410015216.5 provides a blood collection container, in particular to a collection container for mononuclear cells and platelet-rich plasma, which comprises an outer tube and an inner tube, wherein a support member is arranged in the outer tube, the inner tube is arranged in the outer tube through the support member, the inner wall of the outer tube is tightly contacted with the outer wall of the inner tube, but is not locked, and the inner tube is easy to pull out; cell separating liquid, separating gel and anticoagulant are preset in the inner tube from bottom to top in sequence, and a pore plastic adhesive layer is embedded on the tube wall of the anticoagulant; vacuumizing the inner tube, and covering the outer tube and the inner tube with a rubber plug at the same time; the outer tube is labeled.
The method for extracting platelet rich plasma in the prior art is to store human blood in a small test tube and extract platelet concentrate, the general process is that the blood is treated by anticoagulant after being separated in vitro, red blood cells with higher specific gravity are firstly removed under certain centrifugation conditions, then liquid components of the blood are taken for secondary centrifugation, platelet poor plasma with lower specific gravity is removed again according to the principle of gradient density, and the platelet rich plasma is reserved for being applied to the required field. The disadvantage of this method is that after the blood has been isolated, it is necessary to use anticoagulants, which are exogenous anticoagulant substances, which activate platelets and other growth factors in vitro and destroy the primordial properties of the blood. In addition, under the action of anticoagulant, fibrinogen in blood can not be converted into fibrin, and thrombin and activator calcium ions are added at a later stage to promote fibrin formation. Whole operation process is loaded down with trivial details, easy the pollution to the shortcoming such as plane drop is easily followed from placing to the difficult placing of small test tube, consequently needs urgent need to develop a blood collection container of rich platelet fibrin of separation.
Disclosure of Invention
The invention aims to provide a blood collection container for separating platelet-rich fibrin, which solves the problems that the operation steps are complicated by adopting a small test tube, anticoagulant is required to be added, the small test tube is easy to fall off and the like in the background technology.
The technical scheme of the invention is as follows: a blood collection container for separating platelet-rich fibrin comprises an outer tube, wherein a safety cap is arranged at the top of the outer tube, a base is arranged at the bottom of the outer tube, and an inner tube is inserted into the outer tube;
the inner tube includes upper tube body and lower tube body, the bottom outer wall integrated into one piece of upper tube body has last cone, the top outer wall integrated into one piece of lower tube body has lower cone, integrated into one piece has the connecting pipe between last cone and the lower cone, be formed with the water storage chamber between inner tube and the outer tube naturally, the bottom inner wall of outer tube is provided with the circular arc end, the bottom outer wall of inner tube is provided with spherical end.
Furthermore, the bottom outer wall integrated into one piece of outer tube has the connecting neck, the bottom outer wall integrated into one piece of connecting neck has the connecting block, the bottom outer wall of connecting block is provided with the conical surface.
Furthermore, the outer wall of the top of the base is provided with a connecting hole, and the inner wall of the bottom of the connecting hole is provided with a lower conical surface.
Furthermore, a retaining groove is naturally formed between the connecting block and the outer pipe, and a retaining ring is integrally formed on the inner wall of the connecting hole.
Furthermore, the connecting block is matched with the connecting hole, and the anti-backing ring is matched with the anti-backing groove.
Furthermore, the outer wall of the bottom of the base is provided with a bottom arc surface, and the outer wall of the safety helmet is provided with anti-skid grains.
Furthermore, the outer wall of the bottom of the safety helmet is provided with an insertion groove, and the tops of the inner pipe and the outer pipe are inserted into the insertion groove.
Furthermore, a cone plug is naturally formed inside the insertion groove and inserted into the inner pipe.
Furthermore, the top outer wall of safety helmet is provided with the recess, the bottom inner wall of recess is provided with the patchhole, the bottom outer wall of safety helmet is provided with the bell mouth.
Furthermore, the inner wall of inner tube is provided with the antifouling layer, the top outer wall integrated into one piece of inner tube has the chimb.
The invention provides a blood collecting container for separating platelet-rich fibrin by improving, compared with the prior art, the following improvements and advantages:
(1) the inner tube is made into a structure that the diameter of the upper tube body and the diameter of the lower tube body are larger than that of the connecting tube, so that plasma rich in platelets and fibrin can be separated at one time when blood is centrifuged, and the extraction of the plasma rich in platelets is more convenient.
(2) The invention adds cooling water into the water storage cavities of the inner tube and the outer tube, so that the blood can not be rapidly aggregated under the low-temperature action of the inner tube, and the anticoagulant is not needed to be used, thereby preventing the platelets and other growth factors in the plasma from being activated in vitro, and further realizing that the originality of the blood is not damaged.
(3) According to the invention, the bottom cambered surface is arranged at the bottom of the base, so that the blood sampling container can be adsorbed on the placing plane through the base, the placing of the blood sampling container is more convenient, and the blood sampling container is prevented from being damaged due to the fact that the blood sampling container easily rolls off the placing plane.
(4) The blood sampling container is more convenient to assemble and connect by utilizing the connecting block to be spliced with the connecting hole of the base, so that the blood sampling container is easier to produce, and the production efficiency of the blood sampling container is improved.
Drawings
The invention is further explained below with reference to the figures and examples:
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic cross-sectional view of the present invention;
FIG. 3 is a schematic view of the inner tube construction of the present invention;
FIG. 4 is an enlarged view of the invention at A;
fig. 5 is an enlarged view of the present invention at B.
Description of reference numerals:
the anti-fouling safety helmet comprises an outer pipe 1, a safety helmet 2, a base 3, a groove 4, a conical hole 5, a conical plug 6, an insertion groove 7, an inner pipe 8, a connecting block 9, a bottom cambered surface 10, an upper pipe 11, a lower pipe 12, an upper cone 13, a lower cone 14, a connecting pipe 15, a spherical bottom 16, a circular bottom 17, a connecting neck 18, anti-skid lines 19, an insertion hole 20, a water storage cavity 21, a backstop groove 22, a convex edge 23, an upper conical surface 24, a backstop ring 25, a connecting hole 26, a lower conical surface 27 and an anti-fouling layer 28.
Detailed Description
The present invention will be described in detail with reference to fig. 1 to 5, and the technical solutions in the embodiments of the present invention will be clearly and completely described, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
A blood collection container for separating platelet-rich fibrin comprises an outer tube 1, wherein the outer tube 1 is made of a plastic material, so that the manufacturing cost is saved, a safety cap 2 is arranged at the top of the outer tube 1, the safety cap 2 is made of a butyl rubber material, a base 3 is arranged at the bottom of the outer tube 1, the base 3 is made of a butyl rubber material, an inner tube 8 is inserted into the outer tube 1, and the inner tube 8 is a glass tube, so that the inner tube 8 is convenient for sterile treatment;
Further, the bottom outer wall of the outer tube 1 is integrally formed with a connecting neck 18, the bottom outer wall of the connecting neck 18 is integrally formed with a connecting block 9, and the bottom outer wall of the connecting block 9 is provided with an upper conical surface 24, so that the connecting block 9 can be conveniently mounted on the base 3.
Furthermore, the outer wall of the top of the base 3 is provided with a connecting hole 26, the inner wall of the bottom of the connecting hole 26 is provided with a lower conical surface 27, and the connecting block 9 is inserted into the connecting hole 26 of the base 3, so that the base 3 is more convenient to mount.
Further, a retaining groove 22 is naturally formed between the connecting block 9 and the outer tube 1, a retaining ring 25 is integrally formed on the inner wall of the connecting hole 26, and the base 3 is prevented from being separated from the outer tube 1 in a natural state by the retaining ring 25 and the retaining groove 22.
Further, the connecting block 9 is fitted to the connecting hole 26, and the retaining ring 25 is fitted to the retaining groove 22, so that the base 3 and the outer tube 1 are fixed to each other.
Further, the bottom outer wall of base 3 is provided with end cambered surface 10, utilizes end cambered surface 10 to make base 3 can adsorb with placing the plane, and then makes that the blood sampling container is placed more stably, and the outer wall of safety helmet 2 is provided with anti-skidding line 19.
Furthermore, the outer wall of the bottom of the safety helmet 2 is provided with an insertion groove 7, and the tops of the inner tube 8 and the outer tube 1 are inserted into the insertion groove 7, so that the safety helmet 2 seals the tops of the inner tube 8 and the outer tube 1.
Furthermore, a cone plug 6 is naturally formed inside the insertion groove 7, and the cone plug 6 is inserted into the inner pipe 8, so that the inner pipe 8 is sealed by the cone plug 6 again.
Further, the top outer wall of safety helmet 2 is provided with recess 4, and the bottom inner wall of recess 4 is provided with patchhole 20, and the bottom outer wall of safety helmet 2 is provided with bell mouth 5, utilizes recess 4, patchhole 20 and bell mouth 5 for safety helmet 2 is convenient for pierce through, and then makes inside the blood stream advances inner tube 8.
Further, the inner wall of inner tube 8 is provided with antifouling layer 28, and the top outer wall integrated into one piece of inner tube 8 has chimb 23, utilizes antifouling layer 28 to make the inner wall of inner tube 8 more smooth.
Firstly, sucking a proper amount of purified water, adding the purified water to the bottom of the outer tube 1, then plugging the inner tube 8 into the outer tube 1, properly fixing, putting the outer tube into a pre-vacuum machine, vacuumizing the outer tube by a proper amount, pressing the safety helmet 2 on the outer tube, and finishing the assembly. Before use, the purified water between the outer tube 1 and the inner tube 8 is frozen by freezing in a 0 ℃ freezer for 30 minutes. Selecting a proper blood taking needle to puncture a vein to collect venous blood, slightly mixing the collected blood after blood collection so as to uniformly cool the blood in the vein, immediately putting the blood in a centrifugal machine, centrifuging the blood for 10-15 minutes at a centrifugal force of 1500-2100G, taking out the blood, sucking out liquid on the upper part of a connecting pipe 15 by using a dispensing injector, wherein the part of the connecting pipe 15 is fibrin rich in platelets, and respectively using the fibrin according to later-stage purposes
Example two
A blood collection container for separating platelet-rich fibrin comprises an outer tube 1, wherein the outer tube 1 is made of a plastic material, so that the manufacturing cost is saved, a safety cap 2 is arranged at the top of the outer tube 1, the safety cap 2 is made of a butyl rubber material, a base 3 is arranged at the bottom of the outer tube 1, the base 3 is made of a butyl rubber material, an inner tube 8 is inserted into the outer tube 1, and the inner tube 8 is a glass tube, so that the inner tube 8 is convenient for sterile treatment;
Further, the bottom outer wall of the outer tube 1 is integrally formed with a connecting neck 18, the bottom outer wall of the connecting neck 18 is integrally formed with a connecting block 9, and the bottom outer wall of the connecting block 9 is provided with an upper conical surface 24, so that the connecting block 9 can be conveniently mounted on the base 3.
Furthermore, the outer wall of the top of the base 3 is provided with a connecting hole 26, the inner wall of the bottom of the connecting hole 26 is provided with a lower conical surface 27, and the connecting block 9 is inserted into the connecting hole 26 of the base 3, so that the base 3 is more convenient to mount.
Further, a retaining groove 22 is naturally formed between the connecting block 9 and the outer tube 1, a retaining ring 25 is integrally formed on the inner wall of the connecting hole 26, and the base 3 is prevented from being separated from the outer tube 1 in a natural state by the retaining ring 25 and the retaining groove 22.
Further, the connecting block 9 is fitted to the connecting hole 26, and the retaining ring 25 is fitted to the retaining groove 22, so that the base 3 and the outer tube 1 are fixed to each other.
Further, the bottom outer wall of base 3 is provided with end cambered surface 10, utilizes end cambered surface 10 to make base 3 can adsorb with placing the plane, and then makes that the blood sampling container is placed more stably, and the outer wall of safety helmet 2 is provided with anti-skidding line 19.
Furthermore, the outer wall of the bottom of the safety helmet 2 is provided with an insertion groove 7, and the tops of the inner tube 8 and the outer tube 1 are inserted into the insertion groove 7, so that the safety helmet 2 seals the tops of the inner tube 8 and the outer tube 1.
Furthermore, a cone plug 6 is naturally formed inside the insertion groove 7, and the cone plug 6 is inserted into the inner pipe 8, so that the inner pipe 8 is sealed by the cone plug 6 again.
Further, the top outer wall of safety helmet 2 is provided with recess 4, and the bottom inner wall of recess 4 is provided with patchhole 20, and the bottom outer wall of safety helmet 2 is provided with bell mouth 5, utilizes recess 4, patchhole 20 and bell mouth 5 for safety helmet 2 is convenient for pierce through, and then makes inside the blood stream advances inner tube 8.
Further, the inner wall of inner tube 8 is provided with antifouling layer 28, and the top outer wall integrated into one piece of inner tube 8 has chimb 23, utilizes antifouling layer 28 to make the inner wall of inner tube 8 more smooth.
Before the inner pipe 8 and the outer pipe 1 are assembled, firstly, the inner pipe 8 is subjected to silicification treatment to enable the inner wall of the inner pipe 8 to be smoother, a proper amount of purified water is sucked and added to the bottom of the outer pipe 1 during assembly, then, the inner pipe 8 is plugged into the outer pipe 1, after the inner pipe is properly fixed, the inner pipe is placed into a pre-vacuum machine to be vacuumized by a proper amount, then, the safety cap 2 is pressed, and the assembly is completed. Before use, the purified water between the outer tube 1 and the inner tube 8 is frozen by freezing in a 0 ℃ freezer for 30 minutes. Selecting a proper blood taking needle to puncture a vein to collect venous blood, slightly mixing the blood after blood collection so as to uniformly cool the blood in the vein, immediately putting the blood in a centrifugal machine, centrifuging the blood for 10-15 minutes at a centrifugal force of 1500-2100G, taking out the blood, sucking out liquid on the upper part of a connecting pipe 15 by using a dispensing injector, wherein the part of the connecting pipe 15 is fibrin rich in platelets, and the fibrin can be respectively used according to later-stage purposes.
EXAMPLE III
A blood collection container for separating platelet-rich fibrin comprises an outer tube 1, wherein the outer tube 1 is made of a plastic material, so that the manufacturing cost is saved, a safety cap 2 is arranged at the top of the outer tube 1, the safety cap 2 is made of a butyl rubber material, a base 3 is arranged at the bottom of the outer tube 1, the base 3 is made of a butyl rubber material, an inner tube 8 is inserted into the outer tube 1, and the inner tube 8 is a glass tube, so that the inner tube 8 is convenient for sterile treatment;
Further, the bottom outer wall of the outer tube 1 is integrally formed with a connecting neck 18, the bottom outer wall of the connecting neck 18 is integrally formed with a connecting block 9, and the bottom outer wall of the connecting block 9 is provided with an upper conical surface 24, so that the connecting block 9 can be conveniently mounted on the base 3.
Furthermore, the outer wall of the top of the base 3 is provided with a connecting hole 26, the inner wall of the bottom of the connecting hole 26 is provided with a lower conical surface 27, and the connecting block 9 is inserted into the connecting hole 26 of the base 3, so that the base 3 is more convenient to mount.
Further, a retaining groove 22 is naturally formed between the connecting block 9 and the outer tube 1, a retaining ring 25 is integrally formed on the inner wall of the connecting hole 26, and the base 3 is prevented from being separated from the outer tube 1 in a natural state by the retaining ring 25 and the retaining groove 22.
Further, the connecting block 9 is fitted to the connecting hole 26, and the retaining ring 25 is fitted to the retaining groove 22, so that the base 3 and the outer tube 1 are fixed to each other.
Further, the bottom outer wall of base 3 is provided with end cambered surface 10, utilizes end cambered surface 10 to make base 3 can adsorb with placing the plane, and then makes that the blood sampling container is placed more stably, and the outer wall of safety helmet 2 is provided with anti-skidding line 19.
Furthermore, the outer wall of the bottom of the safety helmet 2 is provided with an insertion groove 7, and the tops of the inner tube 8 and the outer tube 1 are inserted into the insertion groove 7, so that the safety helmet 2 seals the tops of the inner tube 8 and the outer tube 1.
Furthermore, a cone plug 6 is naturally formed inside the insertion groove 7, and the cone plug 6 is inserted into the inner pipe 8, so that the inner pipe 8 is sealed by the cone plug 6 again.
Further, the top outer wall of safety helmet 2 is provided with recess 4, and the bottom inner wall of recess 4 is provided with patchhole 20, and the bottom outer wall of safety helmet 2 is provided with bell mouth 5, utilizes recess 4, patchhole 20 and bell mouth 5 for safety helmet 2 is convenient for pierce through, and then makes inside the blood stream advances inner tube 8.
Further, the inner wall of inner tube 8 is provided with antifouling layer 28, and the top outer wall integrated into one piece of inner tube 8 has chimb 23, utilizes antifouling layer 28 to make the inner wall of inner tube 8 more smooth.
Firstly, sucking a proper amount of purified water, adding the purified water to the bottom of the outer tube 1, then plugging the inner tube 8 into the outer tube 1, properly fixing, putting the outer tube into a pre-vacuum machine, vacuumizing the outer tube by a proper amount, pressing the safety helmet 2 on the outer tube, and finishing the assembly. Selecting irradiation sterilization according to requirements, and performing aseptic treatment on the product. Before use, the purified water between the outer tube 1 and the inner tube 8 is frozen by freezing in a 0 ℃ freezer for 30 minutes. Selecting a proper blood taking needle to puncture a vein to collect venous blood, slightly mixing the blood after blood collection so as to uniformly cool the blood in the vein, immediately putting the blood in a centrifugal machine, centrifuging the blood for 10-15 minutes at a centrifugal force of 1500-2100G, taking out the blood, sucking out liquid on the upper part of a connecting pipe 15 by using a dispensing injector, wherein the part of the connecting pipe 15 is fibrin rich in platelets, and the fibrin can be respectively used according to later-stage purposes.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. A blood collection container for separating platelet-rich fibrin, comprising: the safety helmet comprises an outer pipe (1), wherein a safety helmet (2) is arranged at the top of the outer pipe (1), a base (3) is arranged at the bottom of the outer pipe (1), and an inner pipe (8) is inserted into the outer pipe (1);
inner tube (8) are including last body (11) and lower body (12), the bottom outer wall integrated into one piece of going up body (11) has last cone (13), the top outer wall integrated into one piece of body (12) has lower cone (14) down, it has connecting pipe (15) to go up integrated into one piece between cone (13) and lower cone (14), be formed with water storage chamber (21) naturally between inner tube (8) and outer tube (1), the bottom inner wall of outer tube (1) is provided with at the bottom of the circular arc (17), the bottom outer wall of inner tube (8) is provided with spherical end (16).
2. A blood collection container for separating platelet rich fibrin according to claim 1, wherein: the outer tube comprises an outer tube (1) and is characterized in that a connecting neck (18) is integrally formed on the outer wall of the bottom of the outer tube, a connecting block (9) is integrally formed on the outer wall of the bottom of the connecting neck (18), and an upper conical surface (24) is arranged on the outer wall of the bottom of the connecting block (9).
3. A blood collection container for separating platelet rich fibrin according to claim 2, wherein: the outer wall of the top of the base (3) is provided with a connecting hole (26), and the inner wall of the bottom of the connecting hole (26) is provided with a lower conical surface (27).
4. A blood collection container for separating platelet rich fibrin according to claim 3, wherein: a retaining groove (22) is naturally formed between the connecting block (9) and the outer pipe (1), and a retaining ring (25) is integrally formed on the inner wall of the connecting hole (26).
5. A blood collection container for separating platelet rich fibrin according to claim 4, wherein: the connecting block (9) is matched with the connecting hole (26), and the retaining ring (25) is matched with the retaining groove (22).
6. A blood collection container for separating platelet rich fibrin according to claim 1, wherein: the bottom outer wall of the base (3) is provided with a bottom cambered surface (10), and the outer wall of the safety helmet (2) is provided with anti-skid grains (19).
7. A blood collection container for separating platelet rich fibrin according to claim 1, wherein: the outer wall of the bottom of the safety cap (2) is provided with an inserting groove (7), and the tops of the inner pipe (8) and the outer pipe (1) are inserted into the inserting groove (7).
8. A blood collection container for separating platelet rich fibrin according to claim 7, wherein: the inner part of the insertion groove (7) is naturally provided with a conical plug (6), and the conical plug (6) is inserted into the inner part of the inner pipe (8).
9. A blood collection container for separating platelet rich fibrin according to claim 1, wherein: the top outer wall of safety helmet (2) is provided with recess (4), the bottom inner wall of recess (4) is provided with patchhole (20), the bottom outer wall of safety helmet (2) is provided with bell mouth (5).
10. A blood collection container for separating platelet rich fibrin according to claim 1, wherein: the inner wall of inner tube (8) is provided with antifouling layer (28), the top outer wall integrated into one piece of inner tube (8) has chimb (23).
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| Application Number | Priority Date | Filing Date | Title |
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| CN202121170767.0U CN215963630U (en) | 2021-05-28 | 2021-05-28 | Blood collection container for separating platelet-rich fibrin |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202121170767.0U CN215963630U (en) | 2021-05-28 | 2021-05-28 | Blood collection container for separating platelet-rich fibrin |
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| CN215963630U true CN215963630U (en) | 2022-03-08 |
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