CN215574651U - Flow type fluorescence detection liquid path system - Google Patents
Flow type fluorescence detection liquid path system Download PDFInfo
- Publication number
- CN215574651U CN215574651U CN202121355918.XU CN202121355918U CN215574651U CN 215574651 U CN215574651 U CN 215574651U CN 202121355918 U CN202121355918 U CN 202121355918U CN 215574651 U CN215574651 U CN 215574651U
- Authority
- CN
- China
- Prior art keywords
- control valve
- outlet
- inlet
- flow
- sheath
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Abstract
The invention discloses a flow type fluorescence detection fluid path system, which aims to overcome the problem of low cleaning efficiency in the prior art and comprises a flow chamber, wherein the flow chamber is provided with a sheath fluid inlet, a sample inlet and a waste fluid outlet, the sheath fluid inlet is connected to a pulsation damper through a fifth control valve, the sample inlet is connected to a sampling device through a seventh control valve, the waste fluid outlet is connected to a waste fluid bottle, the sampling device is provided with a cleaning device, the flow type fluorescence detection fluid path system also comprises a first control valve, the first control valve is provided with a first inlet and two first outlets, one first outlet is connected to the pulsation damper, and the other first outlet is connected to the sheath fluid inlet and the cleaning device.
Description
Technical Field
The invention belongs to the detection technology, and particularly relates to a flow type fluorescence detection liquid path system.
Background
Flow-type fluorescence detection, also known as suspension array, liquid phase chip, etc. The principle of the technology is that a fluorescent coding microsphere is taken as a core, microneedle molecules on the fluorescent coding microsphere can be specifically combined with biomolecules to achieve the effect of fluorescently labeling the biomolecules, the fluorescently-labeled biomolecules are subjected to laser analysis, and then optical signals generated by the laser analysis are subjected to a series of processing to obtain a visual diagnosis result.
The present utility model with the publication number "CN 205209962U" in china discloses a fluid path system of a flow-type fluorescence detector, which utilizes the above fluorescence detection technology, and comprises a sample, a sheath fluid, a swab, a sample injection pump, a sheath fluid injection pump, a peristaltic pump and a flow cell, wherein a first solenoid valve and a second solenoid valve are arranged between the flow cell and the sample injection pump, a third solenoid valve is arranged between the sample injection pump and the sheath fluid, a fourth solenoid valve is arranged at one end of the sheath fluid injection pump, a fifth solenoid valve is arranged at the other end, the fourth solenoid valve is communicated with the sheath fluid, the fifth solenoid valve is communicated with the flow cell, the flow cell is communicated with a waste fluid outlet through a sixth solenoid valve, the swab is communicated with the peristaltic pump through a seventh solenoid valve, the peristaltic pump is arranged between the fourth solenoid valve and the fifth solenoid valve, after each time of detecting the sample or before detecting another sample, the flow cell and the swab need to be cleaned by the sheath fluid, the residual sample is avoided from reducing the detection accuracy.
However, the prior art is not perfect, and if the sheath fluid needs to be cleaned by the peristaltic pump, the internal resistance of the peristaltic pump is high, which causes the problem of low cleaning efficiency.
SUMMERY OF THE UTILITY MODEL
In order to overcome the defects and problems in the prior art, the invention provides a flow type fluorescence detection liquid path system.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides a STREAMING fluorescence detection liquid route system, including flowing the room, it has sheath liquid entry to flow the room, sample entry and waste liquid outlet, sheath liquid entry passes through the fifth control valve and connects on pulsation damper, the sample entry passes through the seventh control valve and connects on sampling device, waste liquid exit linkage is on the waste liquid bottle, the last belt cleaning device that is provided with of sampling device, still include first control valve, first control valve has first entry and two first exports, a first exit linkage is on pulsation damper, another first exit linkage is on sheath liquid entry and belt cleaning device.
In some embodiments, the cleaning device further comprises a sixth control valve having a sixth inlet and two sixth outlets, a first outlet is connected to the sixth inlet, a sixth outlet is connected to the sheath fluid inlet, and the other sixth outlet is connected to the cleaning device.
In some modes, the device further comprises a second three-way pipe, the first end of the second three-way pipe is connected to a sixth outlet, the second end of the second three-way pipe is connected to the sheath liquid inlet, and the third end of the second three-way pipe is connected to the waste liquid bottle through a fourth control valve.
In some modes, a waste liquid pump is connected to the waste liquid bottle.
In some embodiments, the cleaning device further comprises an eighth control valve having an eighth inlet and two eighth outlets, the eighth inlet is connected to the waste liquid pump, one eighth outlet is connected to the cleaning device, and the other eighth outlet is connected to the waste liquid bottle.
In some embodiments, the apparatus further comprises a third control valve, and the waste liquid bottle is connected to the waste liquid outlet through the third control valve.
In some embodiments, the pulsation dampener further comprises a filter, and a first outlet is connected to the pulsation dampener through the filter.
In some modes, the device further comprises a first three-way pipe, the first end of the first three-way pipe is connected with the filter, the second end of the first three-way pipe is connected with the pulsation damper, the third end of the first three-way pipe is connected with a second control valve, and the second control valve is connected with the waste liquid bottle.
In some embodiments, the sheath fluid inlets are two, the pulsation damper is connected to one of the sheath fluid inlets, and a first outlet is connected to the other of the sheath fluid inlets.
In some embodiments, the sheath pump is connected to the first inlet, the seventh control valve has a seventh inlet and two seventh outlets, the sample pump is connected to the seventh inlet, the sample inlet is connected to the seventh outlet, and the sampling device is connected to the other seventh outlet.
Compared with the prior art, the invention has the outstanding and beneficial technical effects that:
(1) in the invention, various valves are adopted to realize the adjustment of the on-off and flow direction of the medium of the pipeline, the functions of detecting, cleaning in a subarea mode, relieving pressure, discharging air in the pipeline and the like are realized, and parts are simple and universal, so the invention has the advantages of simple structure, complete function and low cost.
(2) In the invention, if the flow type fluorescence detection liquid path system is used for detecting a sample, the first control valve controls the sheath liquid to flow to the pulsation damper, the sheath liquid flows to the sheath liquid inlet through the pulsation damper, the pulsation damper improves the medium stability of the sheath liquid, and if the flow type fluorescence detection liquid path system is used for cleaning, the first control valve can also control the medium to directly flow to the sheath liquid inlet and the cleaning device, so that the pulsation damper is prevented from obstructing the flow of the medium, and therefore, the invention has the advantage of high cleaning efficiency.
(3) In the invention, the medium can be cleaned sequentially through the second control valve, the sixth control valve, the flow chamber, the third control valve, the waste liquid bottle, the eighth control valve and the waste liquid pump, and the medium can also be cleaned sequentially through the second control valve, the sixth control valve, the cleaning device, the eighth control valve and the waste liquid pump, so that the flow chamber and the cleaning device can be cleaned in a shunting manner, and the cleaning effect is improved.
(4) In the invention, the medium between the first control valve and the pulsation damper not only has sheath liquid, but also can have air, in order to improve the detection accuracy, the air between the first control valve and the pulsation damper can be normally detected only by discharging the air, if the second control valve is opened, the air between the first control valve and the pulsation damper can be quickly discharged to a waste liquid bottle, if the second control valve is closed, the sheath liquid can normally flow into the pulsation damper, in addition, when the detection is finished, the second control valve can be opened to release the medium between the first control valve and the pulsation damper to the waste liquid bottle, and the pressure accumulation of the medium on the pulsation damper is avoided, therefore, the invention has the advantages of high working efficiency and reliable use.
Drawings
FIG. 1 is a schematic structural diagram of the invention;
in the figure: 1-flow chamber, 2-sampling device, 3-pulsation damper, 4-waste liquid bottle, 5-cleaning device, 6-filter, 71-first control valve, 72-second control valve, 73-third control valve, 74-fourth control valve, 75-fifth control valve, 76-sixth control valve, 77-seventh control valve and 78-eighth control valve, 81-first three-way pipe, 82-second three-way pipe, 91-waste liquid pump, 92-sheath liquid pump, 93-sample pump, 11-sheath liquid inlet, 12-sample inlet, 13-waste liquid outlet, 711-first inlet, 712-first outlet, 761-sixth inlet, 762-sixth outlet, 781-eighth inlet and 782-eighth outlet.
Detailed Description
In order to facilitate the understanding of those skilled in the art, the invention will be further described with reference to the accompanying drawings and specific embodiments.
It will be understood that when an element is referred to as being "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may be present.
Unless defined otherwise, all techniques and sciences used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
As shown in fig. 1, the embodiment of the present invention provides a flow type fluorescence detection fluid circuit system, which includes a flow chamber 1, a pulsation damper 3, a seventh control valve 77, a sampling device 2, a washing device 5, and a first control valve 71.
The flow cell 1 has a sheath fluid inlet 11, a sample inlet 12 and a waste fluid outlet 13.
Wherein the sheath fluid inlet 11 refers to an opening through which the sheath fluid flows into the flow chamber 1. Sample inlet 12 refers to an opening through which sample flows into flow cell 1. The waste liquid outlet 13 refers to an opening through which the detected waste liquid flows out of the flow cell 1.
The sheath fluid inlet 11 is connected to the pulsation damper 3 through a fifth control valve 75.
And a fifth control valve 75, and the pulsation damper 3 is connected to the sheath fluid inlet 11 through the fifth control valve 75.
The pulsation damper 3 is a pressure vessel for eliminating sheath fluid pressure pulsation, and plays a role in stabilizing sheath fluid pressure and flow rate and protecting downstream equipment, and the sheath fluid can flow to the sheath fluid inlet 11 through the pulsation damper 3 and the fifth control valve 75.
The fifth control valve 75 is used to control the on/off between the pulsation damper 3 and the sheath fluid inlet 11. When the fifth control valve 75 is opened, the pulsation damper 3 communicates with the sheath fluid inlet 11. When the fifth control valve 75 is closed, the communication between the pulsation damper 3 and the sheath fluid inlet 11 is blocked.
In practical use, if the present flow-type fluorescence detection fluid path system is used for detecting a sample, the fifth control valve 75 is opened; if the flow type fluorescence detection fluid path system is used for cleaning, the fifth control valve 75 is closed to prevent the sheath fluid in the flow chamber 1 from flowing back to the pulsation damper 3.
Specifically, the fifth control valve 75 is an electromagnetic valve, and the opening and closing of the fifth control valve 75 can be automatically controlled by a controller, so that the automation of the control is realized.
The sample inlet 12 is connected to the sampling device 2 via a seventh control valve 77.
Wherein the sampling device 2 is used for collecting samples. The sample refers to blood, body fluid, tissue fluid, and the like of a living organism. The sample collected by the sampling device 2 is indirectly delivered to the sample inlet 12 through a seventh control valve 77, and the seventh control valve 77 is used to control whether the sample flows to the sample inlet 12.
In particular, the sampling device 2 is a sampling needle. The sampling needle refers to a needle-shaped tube body with an integral structure. If the sampling needle is inserted into a sample, the sampling needle can suck the sample into the sampling needle under the action of negative pressure.
The waste liquid outlet 13 is connected to the waste liquid bottle 4.
Wherein, the waste liquid bottle 4 is hollow and is used for temporarily storing waste liquid. The waste liquid refers to a mixed liquid of sheath liquid, sample, and the like.
The sampling device 2 is provided with a cleaning device 5.
The cleaning device 5 is used for cleaning the sampling device 2. The sample remaining on the sampling device 2 is prevented from contaminating the next sample collected.
Specifically, the cleaning device 5 is a swab, and the swab is sleeved on the sampling device 2. When the sheath liquid flows on the swab, the sheath liquid can flow on the surface of the sampling device 2, so as to clean the sampling device 2, and the specific structure of the swab can refer to a swab for cleaning a sampling needle with the publication number "CN 208019077U".
Further, a first control valve 71 is provided, the first control valve 71 having a first inlet 711 and two first outlets 712, one first outlet 712 being connected to the pulsation damper 3, and the other first outlet 712 being connected to the sheath fluid inlet 11 and the cleaning device 5.
Wherein the first control valve 71 can change the flow direction of the medium. If a first outlet 712 is opened and another first outlet 712 is closed, the medium flowing in from the first inlet 711 can flow to the pulsation damper 3 through a first outlet 712. When one first outlet 712 is closed and the other first outlet 712 is opened, the medium flowing in from the first inlet 711 can flow to the sheath fluid inlet 11 and the cleaning device 5 through the other first outlet 712. In practical use, the medium can be a sheath fluid, and the sheath fluid can be used for detection and cleaning.
Specifically, the first control valve 71 is an electromagnetic three-way valve, and the flow direction of the sheath fluid of the first control valve 71 can be automatically controlled by a controller, so that automation of control is realized.
In the invention, if the flow type fluorescence detection fluid path system is used for detecting a sample, the first control valve 71 controls the sheath fluid to flow to the pulsation damper 3, the sheath fluid flows to the sheath fluid inlet 11 through the pulsation damper 3, and the pulsation damper 3 improves the medium stability of the sheath fluid; if the flow type fluorescence detection liquid path system is used for cleaning, the first control valve 71 can also control the medium to directly flow to the sheath liquid inlet 11 and the cleaning device 5, so that the pulsation damper 3 is prevented from obstructing the flow of the medium, and therefore, the flow type fluorescence detection liquid path system has the advantages of simple structure, high cleaning efficiency and accurate detection.
The sixth control valve 76 is further included, and the sixth control valve 76 has a sixth inlet 761 and two sixth outlets 762, wherein a first outlet 712 is connected to the sixth inlet 761, a sixth outlet 762 is connected to the sheath fluid inlet 11, and the other sixth outlet 762 is connected to the cleaning device 5.
Wherein the sixth control valve 76 may change the flow direction of the sheath fluid. When a sixth outlet 762 is opened and another sixth outlet 762 is closed, the sheath fluid flowing from the sixth inlet 761 can flow to the sheath fluid inlet 11 through a sixth outlet 762. When one sixth outlet 762 is closed and the other sixth outlet 762 is opened, the sheath fluid flowing in from the sixth inlet 761 passes through the other sixth outlet 762 to clean the device 5. Thus, a split flushing of the cleaning device 5 and the flow chamber 1 is achieved.
Specifically, the sixth control valve 76 is an electromagnetic three-way valve, and the sheath fluid flow direction of the sixth control valve 76 can be automatically controlled by a controller, so that automation of control is realized.
The device further comprises a second three-way pipe 82, wherein a first end of the second three-way pipe 82 is connected to a sixth outlet 762, a second end of the second three-way pipe 82 is connected to the sheath fluid inlet 11, and a third end of the second three-way pipe 82 is connected to the waste liquid bottle 4 through a fourth control valve 74.
Wherein the second tee 82 is a tube with three openings. If the fourth control valve 74 is opened, the sheath fluid flowing into the second tee pipe 82 may flow to the waste liquid bottle 4 through the fourth control valve 74. If the fourth control valve 74 is closed, the sheath fluid flowing into the second tee 82 can flow out only through the sheath fluid inlet 11.
Specifically, the fourth control valve 74 is a solenoid valve, and the opening and closing of the fourth control valve 74 can be automatically controlled by a controller, so that the control is automated.
The waste liquid bottle 4 is connected with a waste liquid pump 91.
Wherein, the waste liquid pump 91 is used for driving the waste liquid in the waste liquid bottle 4 to flow to the waste liquid pump 91 and discharge.
The cleaning device further comprises an eighth control valve 78, an eighth inlet 781 and two eighth outlets 782 of the eighth control valve 78, wherein the eighth inlet 781 is connected to the waste liquid pump 91, one eighth outlet 782 is connected to the cleaning device 5, and the other eighth outlet 782 is connected to the waste liquid bottle 4.
Wherein the eighth control valve 78 is used for controlling the flow direction of the medium. If an eighth outlet 782 is open and a further eighth outlet 782 is closed, the waste-liquid pump 91 can drive the medium over the cleaning device 5. If an eighth outlet 782 is closed and another eighth outlet 782 is open, the waste liquid pump 91 can drive the medium to flow on the waste liquid bottle 4.
Specifically, the eighth control valve 78 is an electromagnetic three-way valve, and the sheath fluid flow direction of the eighth control valve 78 can be automatically controlled by a controller, so that the automation of the control is realized.
In practical use, the sheath liquid can sequentially pass through the second control valve 72, the sixth control valve 76, the flow chamber 1, the third control valve 73, the waste liquid bottle 4, the eighth control valve 78 and the waste liquid pump 91 for cleaning, and the sheath liquid can also sequentially pass through the second control valve 72, the sixth control valve 76, the cleaning device 5, the eighth control valve 78 and the waste liquid pump 91 for cleaning, so that shunting cleaning of the flow chamber 1 and the cleaning device 5 is realized, and the cleaning effect is improved.
The waste liquid outlet 13 is connected to the waste liquid bottle 4 through a third control valve 73.
The third control valve 73 is used for controlling the connection and disconnection between the waste liquid outlet 13 and the waste liquid bottle 4. When the third control valve 73 is opened, the waste liquid outlet 13 is communicated with the waste liquid bottle 4. When the third control valve 73 is turned off, the communication between the waste liquid outlet 13 and the waste liquid bottle 4 is blocked.
Specifically, the third control valve 73 is an electromagnetic valve, and the opening and closing of the third control valve 73 can be automatically controlled by the controller, so that the automation of the control is realized.
Further includes a filter 6, and a first outlet 712 is connected to the pulsation damper 3 through the filter 6.
Wherein the filter 6 is used for filtering impurities in the sheath fluid flowing into the pulsation damper 3. The problem of detection accuracy decline caused by impurities in the sheath liquid entering the flow chamber 1 is avoided.
The waste liquid bottle filter further comprises a first three-way pipe 81, the first end of the first three-way pipe 81 is connected to the filter 6, the second end of the first three-way pipe 81 is connected to the pulsation damper 3, the third end of the first three-way pipe 81 is connected with a second control valve 72, and the second control valve 72 is connected to the waste liquid bottle 4.
The first three-way pipe 81 is a pipe having three openings. When the second control valve 72 is opened, the medium between the first control valve 71 and the pulsation damper 3 can flow into the waste liquid bottle 4 through the second control valve 72. If the second control valve 72 is closed, the medium between the first control valve 71 and the pulsation damper 3 can only flow out through the pulsation damper 3.
Specifically, the second control valve 72 is an electromagnetic valve, and the opening and closing of the second control valve 72 can be automatically controlled by a controller, so that the automation of the control is realized.
In practical use, the medium between the first control valve 71 and the pulsation damper 3 not only contains sheath fluid, but also can contain air, in order to improve the detection accuracy, the air between the first control valve 71 and the pulsation damper 3 needs to be discharged to be normally detected, if the second control valve 72 is opened, the air between the first control valve 71 and the pulsation damper 3 can be rapidly discharged to the waste liquid bottle 4, if the second control valve 72 is closed, the sheath fluid can normally flow into the pulsation damper 3, in addition, when the detection is finished, the second control valve 72 can be opened to release the medium between the first control valve 71 and the pulsation damper 3 to the waste liquid bottle 4, so that the pressure accumulation of the medium on the pulsation damper 3 is avoided, and the invention has the advantages of high working efficiency and reliable use.
The number of the sheath fluid inlets 11 is two, a first outlet 712 is connected to one of the sheath fluid inlets 11, and the fifth control valve 75 is connected to the other of the sheath fluid inlets 11.
The two sheath liquid inlets 11 are independent from each other, and when the flow type fluorescence detection liquid path system is cleaned or detected, interference is generated between the two sheath liquid inlets, so that the working reliability of the invention is improved.
Specifically, two sheath liquid inlets 11 are symmetrically disposed on two sides of the flow chamber 1, and the two sheath liquid inlets 11 are respectively communicated with the inner cavity of the flow chamber 1.
A sheath fluid pump 92 is connected to the first inlet 711.
The sheath fluid pump 92 is configured to deliver the sheath fluid to the first inlet 711, providing a pressure for delivering the sheath fluid.
Further comprising a sample pump 93, the seventh control valve 77 having a seventh inlet 771 and two seventh outlets 772, the sample pump 93 being connected to the seventh inlet 771, the sample inlet being connected to one of the seventh outlets 772 and the sampling means 2 being connected to the other of the seventh outlets 772.
Wherein the sample pump 93 is used to provide a negative pressure to the sampling device 2 and the sample pump 93 is also used to provide a positive pressure to the sampling inlet 12. The seventh control valve 77 is used to change the flow direction of the medium. If a seventh outlet 772 is open and another seventh outlet 772 is closed, the sample on the sampling device 2 may flow into the sample pump 93. If a seventh outlet 772 is closed and another seventh outlet 772 is open, the sample in the sample pump 93 can flow into the sample inlet 12.
Specifically, the seventh control valve 77 is an electromagnetic three-way valve, and the sample flow direction on the seventh control valve 77 can be automatically controlled by the controller, so that automation of control is realized.
The sample pump 93 is used to deliver the sample on the sampling device 2 to the seventh control valve 77.
The detection method of the present flow-type fluorescence detection liquid path system is described as follows:
and starting the sample pump 93, controlling the seventh control valve 77 to communicate the sample pump 93 with the sampling device 2, and collecting the sample by the sample pump 93 through the sampling device 2.
If a sufficient amount of sample is collected by the sampling device 2, the sheath liquid pump 92 is started, the seventh control valve 77 is controlled to be communicated with the sample pump 93 and the sample inlet 12, the first control valve 71 is controlled to be communicated with the sheath liquid pump 92 and the filter 6, the second control valve 72 is closed, the third control valve 73 is opened, the fourth control valve 74 is closed, the fifth control valve 75 is opened, the sixth control valve 76 is controlled to be blocked from being communicated with the first control valve 71 and the flow chamber 1, the eighth control valve 78 is controlled to be communicated with the waste liquid bottle 4 and the waste liquid pump 91, the sheath liquid sequentially passes through the sheath liquid pump 92, the first control valve 71, the filter 6, the pulsation damper 3, the fifth control valve 75, the flow chamber 1, the third control valve 73 and the waste liquid bottle 4, and the sample sequentially passes through the pump 93, the seventh control valve 77, the flow chamber 1, the third control valve 73 and the waste liquid bottle 4.
When the sampling device 2 is cleaned, the sheath liquid pump 92 and the waste liquid pump 91 are started, the first control valve 71 is controlled to be communicated with the sheath liquid pump 92 and the sixth control valve 76, the sixth control valve 76 is controlled to be communicated with the first control valve 71 and the cleaning device 5, the eighth control valve 78 is controlled to be communicated with the cleaning device 5 and the waste liquid pump 91, and the sheath liquid can sequentially pass through the sheath liquid pump 92, the first control valve 71, the sixth control valve 76, the cleaning device 5, the eighth control valve 78 and the waste liquid pump 91, so that the sampling device 2 is cleaned.
When the flow chamber 1 is cleaned, the sheath liquid pump 92 and the waste liquid pump 91 are opened, the first control valve 71 is controlled to be communicated with the sheath liquid pump 92 and the sixth control valve 76, the sixth control valve 76 is controlled to be communicated with the first control valve 71 and the flow chamber 1, the fourth control valve 74 is closed, the third control valve 73 is opened, the eighth control valve 78 is controlled to be communicated with the waste liquid bottle 4 and the waste liquid pump 91, the sheath liquid can sequentially pass through the sheath liquid pump 92, the first control valve 71, the sixth control valve 76, the second three-way pipe 82, the flow chamber 1, the third control valve 73, the waste liquid bottle 4, the eighth control valve 78 and the waste liquid pump 91, and therefore the cleaning of the flow chamber 1 is achieved.
The above embodiments are only preferred embodiments of the present invention, and the protection scope of the present invention is not limited thereby, so: all equivalent changes made according to the structure, shape and principle of the invention shall be covered within the protection scope of the invention.
Claims (10)
1. The utility model provides a STREAMING fluorescence detection liquid route system, including flowing the room, it has sheath liquid entry to flow the room, sample entry and waste liquid outlet, a serial communication port, sheath liquid entry passes through the fifth control valve and connects on the pulsation damper, the sample entry passes through the seventh control valve and connects on sampling device, waste liquid exit linkage is on the waste liquid bottle, the last belt cleaning device that is provided with of sampling device, still include first control valve, first control valve has first entry and two first exports, a first exit linkage is on the pulsation damper, another first exit linkage is on sheath liquid entry and belt cleaning device.
2. A flow-through fluorescence detection fluid circuit system according to claim 1, further comprising a sixth control valve having a sixth inlet and two sixth outlets, a first outlet connected to the sixth inlet, a sixth outlet connected to the sheath fluid inlet, and another sixth outlet connected to the cleaning device.
3. The flow fluorescence detection fluid circuit system of claim 2, further comprising a second tee, wherein a first end of the second tee is connected to a sixth outlet, a second end of the second tee is connected to the sheath fluid inlet, and a third end of the second tee is connected to the waste fluid bottle via a fourth control valve.
4. A flow-through fluorescence detection fluid circuit system according to claim 1, 2 or 3, wherein a waste fluid pump is connected to the waste fluid bottle.
5. A flow-type fluorescence detection fluid circuit system according to claim 4, further comprising an eighth control valve having an eighth inlet and two eighth outlets, wherein the eighth inlet is connected to the waste fluid pump, one eighth outlet is connected to the cleaning device, and the other eighth outlet is connected to the waste fluid bottle.
6. A flow-type fluorescence detection fluid path system according to claim 1, 2, 3 or 5, further comprising a third control valve, wherein the waste liquid bottle is connected to the waste liquid outlet via the third control valve.
7. A flow-through fluorescence detection fluid circuit system according to claim 1, further comprising a filter, a first outlet connected to the pulsation damper through the filter.
8. The flow fluorescence detection fluid circuit system of claim 7, further comprising a first tee, wherein a first end of the first tee is connected to the filter, a second end of the first tee is connected to the pulsation damper, a third end of the first tee is connected to a second control valve, and the second control valve is connected to the waste liquid bottle.
9. A flow-through fluorescence detection fluid path system as claimed in claim 1, wherein said sheath fluid inlets are two, the pulsation damper is connected to one sheath fluid inlet, and a first outlet is connected to the other sheath fluid inlet.
10. A flow fluorescence detection fluid circuit system according to claim 1 wherein a sheath pump is connected to the first inlet, the seventh control valve has a seventh inlet and two seventh outlets, a sample pump is connected to the seventh inlet, a seventh outlet is connected to the sample inlet, and a sampling device is connected to the other seventh outlet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121355918.XU CN215574651U (en) | 2021-06-17 | 2021-06-17 | Flow type fluorescence detection liquid path system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121355918.XU CN215574651U (en) | 2021-06-17 | 2021-06-17 | Flow type fluorescence detection liquid path system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215574651U true CN215574651U (en) | 2022-01-18 |
Family
ID=79818181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121355918.XU Active CN215574651U (en) | 2021-06-17 | 2021-06-17 | Flow type fluorescence detection liquid path system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215574651U (en) |
-
2021
- 2021-06-17 CN CN202121355918.XU patent/CN215574651U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104897557B (en) | FCM analysis liquid-way system and FCM analysis method | |
| US8549934B2 (en) | Segmented online sampling apparatus and method of use | |
| CN103837462B (en) | A kind of small-sized flow cytometer liquid-way system | |
| CN110031386B (en) | Flow cytometer liquid path system and detection method thereof | |
| CN204630897U (en) | FCM analysis liquid-way system | |
| CN207919694U (en) | a kind of closestool | |
| CN209296733U (en) | Sample analysis liquid channel system, sample analyser | |
| CN106007031A (en) | Water purifier and raw water pressure state detection system thereof | |
| CN100364637C (en) | Intelligent vacuum filtering instrument and its control method | |
| CN108753576A (en) | A kind of fermentation tank on-line period dilution system and its technique | |
| CN210071617U (en) | Flow cytometer liquid path system | |
| CN215574651U (en) | Flow type fluorescence detection liquid path system | |
| CN113390845A (en) | Flow type fluorescence detection liquid path system | |
| WO2022001370A1 (en) | Liquid path system for sheath flow, and control method | |
| CN110118718A (en) | Liquid fluid system, test method, the regulation method of negative pressure device and flow cytometer | |
| CN105776618B (en) | Filter device | |
| US20160090617A1 (en) | Concentration device for microorganisms in large volumes of turbid water and method therefor | |
| CN108414338A (en) | A kind of bubble evenly mixing device | |
| CN202227458U (en) | Draining and silt-discharging system | |
| CN112816720A (en) | Full-automatic cell harvesting instrument of integrated liquid path system | |
| CN203069039U (en) | Intelligent cleaning unit for dosing rubber balls | |
| CN111607499B (en) | Automatic sampling device and method for fermentation tank with multiple machines sharing sampling interface | |
| CN104792601A (en) | Online filtering device of drilling mud | |
| CN214668096U (en) | Sample detection device and suction mechanism thereof | |
| CN110007102A (en) | A kind of liquid relief accurate quantification sampling device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |