CN215162676U

CN215162676U - Nucleic acid detector for constant temperature amplification and gene editing

Info

Publication number: CN215162676U
Application number: CN202120402840.6U
Authority: CN
Inventors: 许恩顺; 梁宁孝; 王海珍; 何奕辉
Original assignee: Nanjing Diji Biotechnology Co ltd
Current assignee: Nanjing Diji Biotechnology Co ltd
Priority date: 2021-02-23
Filing date: 2021-02-23
Publication date: 2021-12-14
Anticipated expiration: 2031-02-23

Abstract

The utility model relates to a nucleic acid testing appearance technical field just discloses a nucleic acid testing appearance for constant temperature amplification and gene editing, including the detector main part, the top of detector main part has been seted up and has been detected the groove, fixedly connected with display screen on the lateral wall of detector main part, fixedly connected with is located the operation panel of display screen below on the lateral wall of detector main part, and the top fixedly connected with fixed column of detector main part has seted up the sliding hole on the fixed column, and sliding connection has the sliding plate in the sliding hole, has seted up spacing hole on the sliding plate, and sliding connection has the gag lever post in the spacing hole, and the top of gag lever post and bottom respectively with the top inner wall and the bottom inner wall fixed connection of corresponding sliding hole. The utility model discloses a to the upper and lower regulation of dropping the medicine head and the convenient dropwise add liquid medicine in location, through the setting of filter screen, can filter the liquid medicine for the liquid medicine is more pure, easy operation, and detection effect is good, has satisfied user's needs.

Description

Nucleic acid detector for constant temperature amplification and gene editing

Technical Field

The utility model relates to a nucleic acid detector technical field especially relates to a nucleic acid detector for constant temperature amplification and gene editing.

Background

From the development history of test reagent products, four important major technological stage evolutions can be distinguished, including chemical analysis techniques, enzymatic analysis techniques, immunoassay techniques, and molecular biological analysis techniques. The molecular diagnosis has the characteristics of high specificity and sensitivity, real-time rapidness and the like, and therefore, the molecular diagnosis plays a leading role in the development process of future test reagents. The trend of the new generation of molecular diagnostics is mainly toward faster diagnosis, easier operation, lower price and the ability to perform point-of-care tests (POCTs).

At present, in China, the diagnosis is convenient and quick without expensive instruments in the process of the reform of a graded triage medical system, is suitable for the application of primary medical units and on-site (Onsite) detection, and undoubtedly has important academic significance and market value. With the continuous expansion of the health care market, the demand of the related inspection market is also expanded year by year. The future molecular diagnostic product market development must also be oriented towards POCT products that can perform nucleic acid tests both in the laboratory (lab) and in the field. Rapid, sensitive molecular diagnostics can be applied to a variety of aspects, such as detection of epidemic pathogens, detection of specific genes on physical examination, resolution of genotyping, and various laboratory research tasks. Has great significance for preventing the spread of infectious diseases, screening diseases at early stage and accelerating the laboratory experiment progress.

In the existing nucleic acid detector, the function of adjusting the detector is not provided, so that the problems of low detection speed and inconvenience in liquid medicine dripping exist, the working efficiency is influenced, and the requirements of users cannot be met.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving among the nucleic acid detecting instrument among the prior art, because of not possessing the function of adjusting to the detector, there is slow, the inconvenient problem of dropwise add liquid medicine of detection speed, has influenced work efficiency, can not satisfy the problem of user's needs, and the nucleic acid detecting instrument who is used for constant temperature amplification and gene editing who proposes.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

a nucleic acid detector for constant temperature amplification and gene editing comprises a detector main body, wherein the top of the detector main body is provided with a detection groove, the side wall of the detector main body is fixedly connected with a display screen, the side wall of the detector main body is fixedly connected with an operation panel positioned below the display screen, the top of the detector main body is fixedly connected with a fixed column, the fixed column is provided with a sliding hole, the sliding hole is internally and slidably connected with a sliding plate, the sliding plate is provided with a limit hole, the limit hole is internally and slidably connected with a limit rod, the top end and the bottom end of the limit rod are respectively and fixedly connected with the top inner wall and the bottom inner wall of the corresponding sliding hole, the bottom of the sliding plate is fixedly connected with a medicine storage box, the sliding plate is provided with a medicine inlet, the medicine inlet is communicated with the medicine storage box, the top of the sliding plate is hinged with a sealing cover, the sealing cover is in sealing fit with the medicine inlet, and the bottom of the medicine storage box is fixedly connected with a medicine dropping pipe, the bottom end of the medicine dripping pipe is fixedly connected with a medicine dripping head which is matched with the detection groove.

Preferably, the bottom of the sliding plate is fixedly connected with a connecting plate, a fixing hole is formed in the connecting plate, a fixing rod is connected in the fixing hole in a sliding mode, a fixing clamping groove is formed in one side, away from the medicine storage box, of the fixing column, one end of the fixing rod is clamped with the fixing clamping groove, and the other end of the fixing rod extends to the outer side of the fixing column and is fixedly connected with a connecting rod.

Preferably, one side that the fixed column was kept away from to the connecting plate has seted up first spout, and sliding connection has first slider in the first spout, the bottom fixedly connected with reset spring of first slider, reset spring's bottom and the bottom inner wall fixed connection of first spout rotate on the first slider and be connected with the rotor plate that the slope set up, and the one end that first slider was kept away from to the rotor plate rotates with the connecting rod to be connected.

Preferably, a second sliding groove is formed in the bottom of the fixing rod, a second sliding block is fixedly connected to the inner wall of the bottom of the fixing hole, the second sliding block is connected with the second sliding groove in a sliding mode, and the inner walls of the two sides of the medicine inlet are fixedly connected with the same filter screen.

Preferably, the bottom four corners of detector main part all rotates and is connected with the walking wheel, and four walking wheels are universal lockable wheels.

Preferably, the number of the fixed clamping grooves is multiple, and the fixed clamping grooves are distributed on one side, far away from the medicine storage box, of the fixed column in the vertical direction at equal intervals.

Compared with the prior art, the utility model provides a nucleic acid detector for constant temperature amplification and gene editing possesses following beneficial effect:

1. according to the nucleic acid detector for constant-temperature amplification and gene editing, the sealing cover is opened, medicine is fed in the medicine inlet, the liquid medicine is filtered through the filter screen, so that the liquid medicine is more purified, the filtered liquid medicine enters the medicine storage box through the medicine inlet, and after the medicine is added, the sealing cover is closed, and the medicine inlet is sealed;

2. according to the nucleic acid detector for constant-temperature amplification and gene editing, the connecting rod is pulled to drive the rotating plate to move, the rotating plate drives the first sliding block to move, the fixed rod is moved out of the fixed clamping groove, the fixing of the connecting plate is released, then the connecting plate is pulled to drive the sliding plate to move, the sliding plate is limited through the limiting rod, meanwhile, the sliding plate drives the medicine storage box to move, the medicine storage box drives the medicine dropping pipe to move, and the medicine dropping pipe drives the medicine dropping head to be adjusted up and down;

3. according to the nucleic acid detector for constant-temperature amplification and gene editing, when the medicine dripping head is adjusted to a proper position, the connecting rod is loosened, the fixing rod is clamped into the fixing clamping groove under the spring rebounding action force of the reset spring, the connecting plate is fixed, the sliding plate is fixed, the medicine dripping head is fixed, and medicine liquid is conveniently dripped through up-and-down adjustment and positioning of the medicine dripping head;

and the part that does not relate to among the device all is the same with prior art or can adopt prior art to realize, the utility model discloses a to the convenient dropwise add liquid medicine of upper and lower regulation and the location of dropping the medicine head, through the setting of filter screen, can filter the liquid medicine for the liquid medicine is more pure, easy operation, and detection effect is good, has satisfied user's needs.

Drawings

FIG. 1 is a schematic diagram of a nucleic acid detecting apparatus for isothermal amplification and gene editing according to the present invention;

FIG. 2 is a schematic diagram of a part A of a nucleic acid detecting apparatus for isothermal amplification and gene editing according to the present invention;

FIG. 3 is a schematic diagram of a part B of the nucleic acid detecting apparatus for isothermal amplification and gene editing according to the present invention.

In the figure: the automatic detection device comprises a detector main body 1, a detection groove 2, a display screen 3, an operation panel 4, a fixed column 5, a sliding hole 6, a sliding plate 7, a limiting hole 8, a limiting rod 9, a medicine storage box 10, a medicine inlet 11, a sealing cover 12, a medicine dropping pipe 13, a medicine dropping head 14, a connecting plate 15, a fixing hole 16, a fixing rod 17, a fixing clamping groove 18, a connecting rod 19, a first sliding groove 20, a first sliding block 21, a reset spring 22, a rotating plate 23, a second sliding groove 24, a second sliding block 25 and a filter screen 26.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.

Referring to fig. 1-3, a nucleic acid detecting instrument for constant temperature amplification and gene editing, comprising a main body 1, a detecting groove 2 is provided at the top of the main body 1, a display 3 is fixedly connected to the side wall of the main body 1, an operation panel 4 is fixedly connected to the side wall of the main body 1, a fixing column 5 is fixedly connected to the top of the main body 1, a sliding hole 6 is provided on the fixing column 5, a sliding plate 7 is slidably connected to the sliding hole 6, a spacing hole 8 is provided on the sliding plate 7, a spacing rod 9 is slidably connected to the spacing hole 8, the top and bottom of the spacing rod 9 are respectively fixedly connected to the top inner wall and bottom inner wall of the corresponding sliding hole 6, a medicine storage box 10 is fixedly connected to the bottom of the sliding plate 7, a medicine inlet 11 is provided on the sliding plate 7, the medicine inlet 11 is communicated with the medicine storage box 10, the top of sliding plate 7 articulates there is sealed lid 12, and sealed lid 12 and the sealed cooperation of advancing medicine mouth 11, and the bottom fixedly connected with of explosive storage box 10 drips pencil 13, drips pencil 13's bottom fixedly connected with and drips medicine head 14, and drips medicine head 14 and detect groove 2 looks adaptation.

The utility model discloses in, the bottom fixedly connected with connecting plate 15 of sliding plate 7 has seted up fixed orifices 16 on the connecting plate 15, and sliding connection has dead lever 17 in the fixed orifices 16, and fixed slot 18 has been seted up to one side that explosive box 10 was kept away from to fixed column 5, and dead lever 17's one end clamps with fixed slot 18 mutually, and the other end of dead lever 17 extends to fixed column 5's the outside and fixedly connected with connecting rod 19.

The utility model discloses in, connecting plate 15 keeps away from one side of fixed column 5 and has seted up first spout 20, and sliding connection has first slider 21 in first spout 20, and the bottom fixedly connected with reset spring 22 of first slider 21, reset spring 22's bottom and the bottom inner wall fixed connection of first spout 20 rotate the rotor plate 23 that is connected with the slope setting on the first slider 21, and the one end that first slider 21 was kept away from to rotor plate 23 rotates with connecting rod 19 to be connected.

The utility model discloses in, second spout 24 has been seted up to the bottom of dead lever 17, fixedly connected with second slider 25 on the bottom inner wall of fixed orifices 16, and

second slider

25 and 24 sliding connection of second spout, the same filter screen 26 of fixedly connected with on the both sides inner wall of medicine inlet 11.

The utility model discloses in, the bottom four corners of detector main part 1 all rotates and is connected with the walking wheel, and four walking wheels are universal lockable wheels.

The utility model discloses in, fixed slot 18's quantity is a plurality of, and a plurality of fixed slot 18 are vertical direction equidistance and distribute in the one side that explosive box 10 was kept away from to fixed column 5.

In the utility model, when in use, the sealing cover 12 is opened, the medicine is fed through the medicine inlet 11, the medicine liquid is filtered through the filter screen 26, the medicine liquid is more purified, the filtered medicine liquid enters the medicine storage box 10 through the medicine inlet 11, after the medicine feeding is finished, the sealing cover 12 is closed, the medicine inlet 11 is sealed, then the connecting rod 19 is pulled, the connecting rod 19 drives the rotating plate 23 to move, the rotating plate 23 drives the first slider 21 to move, the first slider 21 compresses the reset spring 22, the energy is absorbed through the reset spring 22, meanwhile, the connecting rod 19 drives the fixing rod 17 to move, the second slider 25 limits the fixing rod 17, the fixing rod 17 is moved out of the fixed clamping groove 18, the fixing of the connecting plate 15 is released, then the connecting plate 15 is pulled, the connecting plate 15 drives the sliding plate 7 to move, the sliding plate 7 is limited through the limiting rod 9, meanwhile, the sliding plate 7 drives the medicine storage box 10 to move, the medicine storage box 10 drives the medicine dropping pipe 13 to move, the medicine dropping pipe 13 drives the medicine dropping head 14 to adjust up and down, the medicine dropping head 14 is adjusted to a proper position, then the connecting rod 19 is loosened, the spring resilience acting force of the reset spring 22 is applied, the fixing rod 17 is clamped into the fixing clamping groove 18, the connecting plate 15 is fixed, the sliding plate 7 is fixed, the medicine dropping head 14 is adjusted up and down and is positioned conveniently, the medicine liquid is dripped conveniently by the aid of the upper and lower adjustment and the positioning of the medicine dropping head 14, the medicine liquid can be filtered by the aid of the filter screen, the medicine liquid is purer, the operation is simple, the detection effect is good, and needs of users are met.

The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims

1. A nucleic acid detector for constant temperature amplification and gene editing comprises a detector main body (1) and is characterized in that a detection groove (2) is formed in the top of the detector main body (1), a display screen (3) is fixedly connected onto the side wall of the detector main body (1), an operation panel (4) positioned below the display screen (3) is fixedly connected onto the side wall of the detector main body (1), a fixed column (5) is fixedly connected onto the top of the detector main body (1), a sliding hole (6) is formed in the fixed column (5), a sliding plate (7) is slidably connected into the sliding hole (6), a limiting hole (8) is formed in the sliding plate (7), a limiting rod (9) is slidably connected into the limiting hole (8), and the top end and the bottom end of the limiting rod (9) are fixedly connected with the top inner wall and the bottom inner wall of the corresponding sliding hole (6) respectively, the bottom fixedly connected with explosive box (10) of sliding plate (7), it advances medicine mouth (11) to have seted up on sliding plate (7), it is linked together with explosive box (10) to advance medicine mouth (11), the top of sliding plate (7) articulates there is sealed lid (12), and sealed lid (12) with advance medicine mouth (11) sealed cooperation, the bottom fixedly connected with of explosive box (10) drips pencil (13), the bottom fixedly connected with of dripping pencil (13) drips pencil head (14), and drip pencil head (14) and detect groove (2) looks adaptation.

2. The nucleic acid detector for constant-temperature amplification and gene editing as claimed in claim 1, wherein a connecting plate (15) is fixedly connected to the bottom of the sliding plate (7), a fixing hole (16) is formed in the connecting plate (15), a fixing rod (17) is slidably connected in the fixing hole (16), a fixing slot (18) is formed in one side of the fixing column (5) away from the medicine storage box (10), one end of the fixing rod (17) is clamped with the fixing slot (18), and the other end of the fixing rod (17) extends to the outer side of the fixing column (5) and is fixedly connected with a connecting rod (19).

3. The nucleic acid detector for constant temperature amplification and gene editing according to claim 2, characterized in that a first sliding groove (20) is formed in one side of the connecting plate (15) away from the fixed column (5), a first sliding block (21) is slidably connected in the first sliding groove (20), a return spring (22) is fixedly connected to the bottom of the first sliding block (21), the bottom end of the return spring (22) is fixedly connected to the inner wall of the bottom of the first sliding groove (20), a rotating plate (23) which is obliquely arranged is rotatably connected to the first sliding block (21), and one end of the rotating plate (23) away from the first sliding block (21) is rotatably connected to the connecting rod (19).

4. The nucleic acid detector for isothermal amplification and gene editing according to claim 2, wherein a second sliding groove (24) is formed at the bottom of the fixing rod (17), a second slider (25) is fixedly connected to the inner wall of the bottom of the fixing hole (16), the second slider (25) is slidably connected to the second sliding groove (24), and the same filter screen (26) is fixedly connected to the inner walls of the two sides of the drug inlet (11).

5. The nucleic acid detector for isothermal amplification and gene editing according to claim 1, wherein four corners of the bottom of the detector body (1) are rotatably connected with traveling wheels, and the four traveling wheels are all universal lockable wheels.

6. The nucleic acid detecting instrument for isothermal amplification and gene editing according to claim 2, wherein the number of the fixing slots (18) is multiple, and the multiple fixing slots (18) are vertically distributed at equal intervals on one side of the fixing column (5) away from the medicine storage box (10).