CN214669120U - Sample analyzer - Google Patents

Abstract

The utility model provides a sample analyzer, which comprises a frame, be provided with the reagent storage module of storage reagent on the frame, a branch injection module for suction row sample or reagent, a reaction module for bearing reagent and sample reaction in the reaction vessel, a washing module that is used for carrying out the detection module that detects and is used for carrying out abluent to the reaction vessel after detecting the completion to the sample after the reaction, the frame has the operation side towards the operator, reaction module sets up in the middle part position department of frame, reagent storage module includes two at least and above reagent storage device, a plurality of reagent storage device set up in the frame, and a plurality of reagent storage device all are close to operator one side and set up, a plurality of reagent storage device set up along reaction module's circumference. Reagent storage blocks on the rack are reasonably arranged, the utilization rate of the space of the rack is improved, the structure of the whole sample analyzer is more compact, the occupied space of the sample analyzer is effectively reduced, and the use experience of a user is also improved.

Description

Sample analyzer

Technical Field

The utility model relates to a sample analyzer equipment technical field particularly, relates to a sample analyzer.

Background

The sample analyzer comprises a biochemical analyzer, a chemiluminescence immunoassay analyzer, a hemagglutination analyzer, a urine analyzer and the like. Taking a biochemical analyzer as an example, the biochemical analyzer is an instrument for detecting chemical components of a certain liquid according to a photoelectric colorimetric principle, is an analysis method established based on selective absorption of a solution to light, namely Lambert-Beer law, and has the advantages of high measurement speed, high accuracy and small reagent consumption. With the rapid development of biomedical equipment, full-automatic biochemical analyzers have become mature medical diagnostic equipment, and the use terminals have higher and higher requirements on the testing speed, the testing stability, the testing accuracy, the reagent capacity and the like of the instruments. In a full-automatic biochemical analyzer, in order to complete a series of test processes such as sample/reagent loading, reaction solution stirring, reaction data acquisition, automatic cleaning of a reaction container, and the like, a reagent storage module, a dispensing module (including a sample filling device and a reagent filling device), a stirring and mixing module, a photoelectric detection module, an automatic cleaning module of a reaction container, and the like need to be respectively configured on the periphery of a reaction module.

Reagent storage module of full-automatic biochemical analysis appearance on the existing market can set up two reagent storage device in the instrument for improving reagent capacity usually to two reagent storage device place in the instrument left and/or right both sides in tandem usually (be preceding for one side that is close to the instrument operation face, keep away from the one side of instrument operation face for the back), the reagent storage device who keeps away from the operation face is not convenient for the operator and gets and put reagent, influences user experience.

SUMMERY OF THE UTILITY MODEL

A primary object of the present invention is to provide a sample analyzer to solve the problem of the prior art that the reagent is inconvenient for the operator to take and place.

In order to achieve the above object, according to one aspect of the present application, there is provided a sample analyzer comprising: the frame, be provided with the reagent storage module of storage reagent in the frame, the branch injection module that is used for suction and discharge sample or reagent, a reaction module that is used for bearing reagent and sample reaction in the reaction vessel, a washing module that is used for carrying out the detection module that detects to the sample after the reaction and is used for detecting the reaction vessel after accomplishing and wasing, the frame has the operation side towards the operator, reaction module sets up in the middle part position department of frame, reagent storage module includes at least two and above reagent storage device, a plurality of reagent storage device set up in the frame, and a plurality of reagent storage device all are close to operator one side and set up, a plurality of reagent storage device set up along reaction module's circumference.

Further, the reaction module includes rotatable and discoid reaction disc that is, and the last at least inside and outside two circles of reaction vessel that are provided with of reaction disc hold the position, and reaction vessel places in holding the position, and each circle includes a plurality of reaction vessel and holds the position.

Further, the reaction module further comprises an incubation tray, which is positioned below the reaction tray and is used for providing a constant temperature reaction environment for the reagent and the sample in the reaction container.

Further, the reagent storage module comprises a first reagent storage device and a second reagent storage device for placing different types of reagents.

Furthermore, the first reagent storage device is arranged on the left side of the operation side, the second reagent storage device is arranged on the right side of the operation side, and the reaction module is arranged between the first reagent storage device and the second reagent storage device and is far away from an operator.

Further, reagent storage module includes rotatable and discoid reagent dish that is, and multiple reagent can be deposited to the reagent dish, and the reagent dish includes that at least inside and outside two circles of reagent deposit the position.

Further, the dispensing module is used for transferring the sample to a reaction container of the reaction module, and the dispensing module is also used for transferring the reagent in the reagent storage module to the reaction container of the reaction module; the dispensing module comprises a first reagent filling device and a second reagent filling device, the first reagent filling device is used for transferring the reagent in the first reagent storage device, and the second reagent filling device is used for transferring the reagent in the second reagent storage device; the first reagent filling device is arranged between the first reagent filling device and the reaction module, and the second reagent filling device is arranged between the second reagent storage device and the reaction module.

Further, at least one of the first reagent filling device and the second reagent filling device is provided with two reagent arms capable of moving independently, the two reagent arms are arranged along the vertical direction in a staggered mode, each reagent arm can move along the vertical direction and can rotate along the horizontal direction, one of the two reagent arms is used for adding reagents to the reaction containers located on the inner ring, and the other reagent arm is used for adding reagents to the reaction containers located on the outer ring.

Further, the cleaning module includes: and the washing liquid stirring device is arranged adjacent to the first reagent filling device, the first reagent storage device and the reaction module, and is used for stirring the reaction container after detection when the reaction container is cleaned.

Furthermore, the cleaning module is arranged adjacent to the reaction module, the cleaning module is positioned between the first reagent filling device and the second reagent filling device and is arranged close to the operation side, and the cleaning module is used for cleaning a reaction vessel in the reaction module.

Further, the sample analyzer further comprises: the stirring module comprises a first stirring device and a second stirring device, and the first stirring device and the second stirring device are arranged adjacent to the reaction module and are used for stirring the sample and the reagent in the reaction container so as to enable the sample and the reagent to fully react; at least one of the first stirring device and the second stirring device is provided with three groups of stirring arms, and each group of stirring arms can move along the vertical direction and can also rotate along the horizontal direction.

Furthermore, at least one group of stirring arms is provided with two stirring pins which are respectively used for stirring the inner ring and the outer ring of the reaction module, and when the stirring pins of one group of stirring arms are used for stirring, the stirring pins of the other two groups of stirring arms can be used for cleaning.

Furthermore, the detection module comprises a first detection device and a second detection device, the first detection device is arranged on the rack and located on the inner side of the reaction module, the first detection device is used for optically detecting an object to be detected in the reaction container on the inner ring of the reaction module, the second detection device is arranged on the rack and located on the outer side of the reaction module, the second detection device is located between the second stirring device and the second reagent filling device, and the second detection device is used for optically detecting the object to be detected in the reaction container on the outer ring of the reaction module.

Furthermore, the first detection device and the second detection device are arranged at intervals of N reaction container accommodating positions along the rotation direction of the reaction disk, wherein N is greater than or equal to 3 and is a positive integer.

Further, the sample analyzer includes: and the cup taking module is positioned below the reaction module and is used for jacking the reaction container so as to assist an operator in taking out the reaction container.

Further, get a cup module and include: the drive part assembly comprises a drive part and a top cup part, the drive part is connected with the incubation disc, the top cup part is arranged on an output shaft of the drive part, and the drive part drives the top cup part to penetrate through the incubation disc to the position below the accommodating position of the reaction vessel so as to eject the reaction vessel to the cup taking position.

Furthermore, along the anticlockwise direction of the reaction module, starting from the test starting position of the reaction module, the reaction module is sequentially provided with a second reagent filling position, a second detection position, a first detection position, a second stirring position, a first sample filling position, a second sample filling position, a first stirring position, a first reagent filling position, a washing liquid stirring position, a cup taking position and a cleaning position, and the cleaning module comprises an inner ring cleaning mechanism and an outer ring cleaning mechanism.

By applying the technical scheme of the utility model, the reagent storage amount of the sample analyzer can be effectively increased by arranging a plurality of reagent storage block storage devices and arranging an inner circle and an outer circle, and simultaneously, the plurality of reagent storage devices are all arranged at the operation side of the frame, so that an operator can conveniently store reagents, and the user experience is improved; meanwhile, a plurality of reagent storage devices are arranged adjacent to the reaction module, so that the occupation of a large instrument space is avoided. The sample analyzer structure reasonably arranges the reagent storage blocks on the rack, improves the utilization rate of the rack space, enables the structure of the whole sample analyzer to be more compact, effectively reduces the occupied space of the sample analyzer, and also improves the use experience of users.

Drawings

The accompanying drawings, which form a part of the present application, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention and not to limit the invention. In the drawings:

fig. 1 shows a schematic structural view of an embodiment of a sample analyzer according to the present invention;

FIG. 2 shows a schematic structural view of an embodiment of the relative positions of the modules of the sample analyzer according to the present invention;

fig. 3 shows a schematic diagram of an embodiment of a detection flow of a sample analyzer according to the present invention;

fig. 4 shows a schematic structural view of an embodiment of an agitation mechanism of a sample analyzer according to the present invention;

fig. 5 shows a schematic structural view of an embodiment of a pin mixer group of a sample analyzer according to the present invention;

fig. 6 shows a schematic structural diagram of an embodiment of a reagent filling device of a sample analyzer according to the present invention.

Wherein the figures include the following reference numerals:

1. a first reagent storage device; 2. a second reagent storage device; 3. a first reagent filling device; 4. a second reagent filling device; 5. a washing liquid stirring device; 6. a cleaning module; 7. a first stirring device; 8. a second stirring device; 9. a first detection device; 10. a second detection device; 11. a first sample filling device; 12. a second sample filling device; 13. an electrolyte module; 14. an incubation tray; 15. a reaction module; 16. a control module;

110. a start bit; 120. taking a cup position;

20. a first vertical lift mechanism;

30. an anti-collision mechanism; 31. positioning a rod; 32. positioning holes;

40. a stirring mechanism; 41. a stirring pin group; 411. a stirring driving motor; 412. a drive gear; 413. a driven gear set; 4131. A first gear; 4132. an intermediate gear; 4133. a second gear;

414. a stirring pin;

42. mounting a disc; 421. a bottom case; 422. an upper cover;

50. a base; 60. a horizontal rotation assembly; 70. a second vertical lift assembly; 80. a cantilever assembly.

Detailed Description

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, and it should be understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof, unless the context clearly indicates otherwise.

It should be noted that the terms "first," "second," and the like in the description and claims of this application and in the drawings described above are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It is to be understood that the terms so used are interchangeable under appropriate circumstances such that the embodiments of the application described herein are, for example, capable of operation in sequences other than those illustrated or otherwise described herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed, but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.

Exemplary embodiments according to the present application will now be described in more detail with reference to the accompanying drawings. These exemplary embodiments may, however, be embodied in many different forms and should not be construed as limited to only the embodiments set forth herein. It is to be understood that these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of the exemplary embodiments to those skilled in the art, in the drawings, it is possible to enlarge the thicknesses of layers and regions for clarity, and the same devices are denoted by the same reference numerals, and thus the description thereof will be omitted.

Referring to fig. 1-3, according to an embodiment of the present application, a sample analyzer is provided.

Specifically, as shown in fig. 1, the sample analyzer includes a rack, a reagent storage module for storing a reagent, a dispensing module for sucking and discharging a sample or a reagent, a reaction module 15 for carrying a reaction between a reagent in a reaction vessel and a sample, a detection module for detecting a reacted sample, and a cleaning module 6 for cleaning a reaction vessel after completion of detection are disposed on the rack, the rack has an operation side facing an operator (as shown in a in fig. 1), the reaction module 15 is disposed at a middle position of the rack, the reagent storage module includes at least two or more reagent storage devices, the plurality of reagent storage devices are disposed on the rack, and the plurality of reagent storage devices are disposed near one side of the operator, and the plurality of reagent storage devices are disposed along a circumferential direction of the reaction module 15.

In the embodiment, the arrangement of the plurality of reagent storage block storage devices and the arrangement of the inner circle and the outer circle can effectively increase the reagent storage amount of the sample analyzer, and meanwhile, the plurality of reagent storage devices are arranged on the operation side of the rack, so that an operator can store reagents conveniently, and the user experience is improved; meanwhile, a plurality of reagent storage devices are arranged adjacent to the reaction module, so that the occupation of a large instrument space is avoided. The sample analyzer structure reasonably arranges the reagent storage blocks on the rack, improves the utilization rate of the rack space, enables the structure of the whole sample analyzer to be more compact, effectively reduces the occupied space of the sample analyzer, and also improves the use experience of users.

Specifically, the reaction module 15 includes a rotatable and discoid reaction disk, and the reaction disk is provided with at least two circles of reaction vessel containing positions inside and outside, and the reaction vessel is placed in containing positions, and each circle includes a plurality of reaction vessel containing positions. And the reaction module 15 further comprises an incubation tray 14, the incubation tray 14 being located below the reaction tray for providing a constant temperature reaction environment for the reagents and samples within the reaction vessels. The reagent storage module comprises a first reagent storage device 1 and a second reagent storage device 2, the first reagent storage device 1 and the second reagent storage device 2 being used for placing different types of reagents. The first reagent storage device 1 is arranged on the left side of the operation side, the second reagent storage device 2 is arranged on the right side of the operation side, and the reaction module 15 is arranged between the first reagent storage device 1 and the second reagent storage device 2 and is far away from an operator. Reagent storage module includes rotatable and be discoid reagent dish, and multiple reagent can be deposited to the reagent dish, and the reagent dish includes that at least inside and outside two circles of reagent deposit the position.

The sample analyzer comprises a dispensing module, the dispensing module is used for transferring a sample to a reaction container of the reaction module, and the dispensing module is also used for transferring a reagent in the reagent storage module to the reaction container of the reaction module; the dispensing module comprises a first reagent filling device 3 and a second reagent filling device 4, wherein the first reagent filling device 3 is used for transferring the reagent in the first reagent storage device 1, and the second reagent filling device 4 is used for transferring the reagent in the second reagent storage device 2; the first reagent filling device 3 is placed between the second reagent filling device 4 and the reaction module, and the second reagent filling device 4 is placed between the second reagent storage device 2 and the reaction module. At least one of the first reagent filling device 3 and the second reagent filling device 4 has two reagent arms capable of independently moving, the two reagent arms are arranged along the vertical direction in a staggered manner, each reagent arm can move along the vertical direction and can also rotate along the horizontal direction, one of the two reagent arms is used for adding reagents to the reaction containers on the inner ring, and the other reagent arm is used for adding reagents to the reaction containers on the outer ring. The cleaning module 6 is arranged adjacent to the reaction module 15, the cleaning module 6 is located between the first reagent filling device 3 and the second reagent filling device 4 and is arranged close to the operation side, and the cleaning module 6 is used for cleaning a reaction vessel in the reaction module 15.

Wherein the first reagent storage device 1 and the second reagent storage device 2 are used to store different types of reagents, it is understood that the first reagent storage device 1 is used to store a first reagent R1 and the second reagent storage device 2 is used to store a second reagent R2, R1 and R2 representing different types of reagents. And first reagent storage device 1 and second reagent storage device 2 take the function of cold-stored and the bar code on the automatic scanning reagent bottle, and first reagent storage device 1 and second reagent storage device 2 all are provided with inner circle and outer lane, set up like this and can increase the carrying capacity of reagent, and the operator can be according to the demand with the reagent bottle that awaits measuring place in inner circle and outer lane. First reagent storage device 1 and second reagent storage device 2 all are close to operator one side, and first reagent storage device 1 places in operation side left side, and second reagent storage device 2 places in operation side right side, and reaction module 15 places between first reagent storage device 1 and second reagent storage device 2, so not only makes instrument compact structure, still makes the operation side need not get into the instrument inside far away one side and can conveniently get and put the reagent bottle.

Furthermore, the two reagent arms are concentrated in one reagent filling device, so that the reagent filling device is compact in structure and small in occupied space, meanwhile, the two reagent arms are arranged in a staggered mode in the vertical direction, mutual interference is avoided, and high-speed operation can be achieved. The reagent arm includes a reagent needle that aspirates a reagent in the reagent storage device into the reaction vessel. The first reagent filling device 3 and the second reagent filling device 4 both have a striker monitoring function (a sensor is arranged on the reagent arm and can monitor the striker). Wherein the sample filling device comprises a sample needle, and the sample needle sucks a sample into the reaction container. It will be appreciated that the sample needle may draw a sample into a sample storage device within the sample analyzer, or onto a sample rack on a track external to the sample analyzer.

In the present full-automatic biochemical analyzer, adopt the structure that a agitating unit was equipped with a stirring needle usually, the stirring needle needs to carry out mixing and two actions of washing in proper order in a stirring cycle, leads to in the short time, is difficult to reach the abundant and sanitization's of mixing effect, and stirring efficiency is lower, can't satisfy the demand of high-speed test.

In order to improve the speed of the stirring device for mixing and cleaning the needles, a plurality of groups of stirring assemblies are configured on the stirring device of some full-automatic biochemical analyzers, each group of stirring assemblies comprises a plurality of stirring needles which are circumferentially and uniformly distributed along the rotating center, the stirring assemblies can be used for stirring reaction solutions in a plurality of reaction containers at one time, and the stirring devices can simultaneously execute the actions of mixing and cleaning the needles in a stirring period. However, each group of stirring assemblies is controlled by an independent drive, so that the stirring speed and direction of each group cannot be absolutely consistent, and unstable factors are brought to test results. The consumption of energy is increased by a plurality of drives, and the energy is not saved and the environment is protected. In addition, the stirring device provided by the prior art does not have an anti-collision function. When the stirring device continues to descend at a non-working position to perform blending or needle cleaning actions, the stirring needle can collide with surrounding parts, so that the stirring needle or the collided parts are damaged, and the normal operation of the instrument is influenced. The prior art has the following defects: the stirring device does not have an anti-collision function, and the damage of the stirring pin can be caused by the impact generated by the stirring device when the stirring device does not act mistakenly.

In order to solve the problem that the stirring pin of sample analyzer among the prior art damaged easily, the sample analyzer that this application provided still includes the stirring module to and wash module 6. The washing module 6 comprises a washing liquid agitation device 5. The washing reagent stirring device 5 is provided adjacent to the first reagent filling device 3, the first reagent storage device 1, and the reaction module 15, and the washing reagent stirring device 5 is used for stirring the reaction container after completion of the detection during the cleaning. The cleaning module 6 is disposed adjacent to the reaction module 15. Cleaning module 6 is located between first reagent filling device 3 and the second reagent filling device 4 and is close to the operation side setting, and cleaning module 6 includes 10 washing needles, is 1 number washing needle, 2 numbers washing needle, 3 numbers washing needle, 4 numbers washing needle, 5 numbers washing needle, 6 numbers washing needle, 7 numbers washing needle, 10 numbers washing needle, 11 numbers washing needle, 12 numbers washing needle respectively. The cleaning module 6 cleans the reaction vessel as follows:

A. the No. 1 cleaning needle is used for pumping away the liquid in the reaction container and injecting deionized water;

B. a No. 2 cleaning needle pumps away deionized water injected periodically in the reaction vessel and injects alkaline cleaning liquid;

C. the reaction module 15 conveys the reaction container to a washing liquid stirring position for washing liquid stirring, so that the washing is more sufficient;

D. the No. 3 cleaning needle pumps the alkaline cleaning solution which is injected into the reaction vessel in the upper period, and injects the acidic cleaning solution;

E. a No. 4 cleaning needle pumps away the acidic cleaning solution which is injected into the reaction vessel in the upper period, and injects deionized water;

F. a No. 5 cleaning needle extracts the deionized water injected periodically in the reaction vessel and injects new deionized water;

G. a No. 6 cleaning needle extracts the deionized water injected periodically in the reaction vessel and injects new deionized water;

H. a No. 7 cleaning needle extracts the deionized water injected periodically in the reaction vessel, and injects new deionized water for cup blank detection;

I. no. 8 and No. 9 positions have no cleaning needle, and cup blank detection is carried out for three times in the period;

J. the No. 10 cleaning needle draws away deionized water for cup blank detection;

K. no. 11 cleaning needles are used for draining residual water in the reaction container;

and pumping residual water in the reaction container again by using an L and 12 cleaning needle to ensure that the reaction container is completely clean.

The cleaning module 6 has a liquid level detection function, and power is cut off to protect the cleaning needle when abnormal conditions such as a striker occur.

The stirring module comprises a first stirring device 7 and a second stirring device 8, and the first stirring device 7 and the second stirring device 8 are arranged adjacent to the reaction module 15 and are used for stirring the sample and the reagent in the reaction container so as to enable the sample and the reagent to fully react; at least one of the first stirring device 7 and the second stirring device 8 is provided with three groups of stirring arms, and each group of stirring arms can move along the vertical direction and can also rotate along the horizontal direction. Wherein, at least a set of rabbling arm is provided with two stirring pins, is used for the stirring of reaction module 15 inner circle and outer lane respectively, and when the stirring pin of one of them group of rabbling arm was used for the stirring, the stirring pin of other two sets of rabbling arms can carry out the cleaning operation. The cleaning operation comprises one or more of pure water cleaning, alkaline liquid cleaning and acid liquid cleaning, so that the cross contamination caused by the stirring needle can be reduced.

Specifically, as shown in fig. 4, the washing liquid stirring device 5 includes a first vertical elevating mechanism 20 and a collision avoidance mechanism 30. The first stirring device 7 and the second stirring device 8 both comprise a stirring mechanism 40, the stirring mechanism 40 is provided with a stirring pin group 41, and the stirring pin group 41 has an operating position and a non-operating position. When the pin group 41 is located at the working position, the pin group 41 can perform stirring and cleaning actions; the first vertical lifting mechanism 20 is connected with the stirring mechanism 40, and the first vertical lifting mechanism 20 can drive the stirring mechanism 40 to move to the working position and the non-working position along the vertical direction. The anti-collision mechanism 30 includes a first positioning member and a second positioning member, and one of the first positioning member and the second positioning member is disposed on the stirring mechanism 40. The other of the first positioning member and the second positioning member is connected to the first vertical lifting mechanism 20. When the first positioning member and the second positioning member are located at the first position, the first vertical lifting mechanism 20 can drive the stirring mechanism 40 to move to the working position and the non-working position, and when the first positioning member and the second positioning member are located at the second position, the anti-collision mechanism 30 prevents the stirring mechanism 40 from moving in the vertical direction, so as to prevent the stirring pin group 41 from being damaged.

In this embodiment, through setting up anticollision institution, make only when first setting element and second setting element are located the complex primary importance, rabbling mechanism 40 could drive the stirring needle group and stir and wash the operation to the operating position, when first setting element and second setting element are located other positions of non-primary importance, rabbling mechanism 40 can not drive the stirring needle group and move to the operating position and stir the operation, set up like this and can prevent when stirring needle group and operating position do not align, when first vertical elevating system 20 drive rabbling mechanism 40 continues to move towards the operating position, restrict rabbling mechanism 40 through anticollision institution, prevent effectively that stirring needle group and other parts from colliding with and the problem of damage, stirring mixing device reliability and life have been improved. It is worth noting that in this application, the first position when first locating piece and second locating piece cooperate is only, and first locating piece and second locating piece are in the position of non-cooperation and have a plurality ofly, and the second position is a plurality of, can guarantee like this that stirring mixing device can only smoothly move to operating position when first locating piece and second locating piece are in the cooperation.

As shown in fig. 5, the stirring mechanism 40 includes a mounting plate 42. The mounting plate 42 is connected to the ball spline shaft, and the pin group 41 includes a stirring drive motor 411, a driven gear group 413, and a pin 414. The stirring drive motor 411 is connected to the mounting plate 42. A driving gear 412 is provided on an output shaft of the agitation driving motor 411. The driven gear set 413 is connected to the mounting plate 42 and is disposed in meshing engagement with the drive gear 412. The pin 414 is connected to the driven gear set 413. The arrangement can improve the reliability of the stirring mechanism 40, and meanwhile, the stirring pin is driven by adopting a gear driving mode, so that the stirring speed of the stirring pin can be effectively controlled, namely, the reliability of the detection structure is improved.

The driven gear set 413 includes a first gear 4131, an intermediate gear 4132, and a second gear 4133. The first gear 4131 is connected with the mounting plate 42. The first gear 4131 is provided in mesh with the drive gear 412. The intermediate gear 4132 is connected to the mounting plate 42, and the intermediate gear 4132 is provided to mesh with the first gear 4131. The second gear 4133 is connected to the mounting plate 42, and the second gear 4133 is provided to mesh with the intermediate gear 4132. The first gear 4131 and the second gear 4133 are provided with the probe 414. The setting can only need the drive through a driving gear can realize that a plurality of pin stirrers stir the cleaning operation like this. The space required by the installation of the stirring pin group is effectively saved, and the practicability and the reliability of the stirring cleaning device are improved. Of course, in the present embodiment, the transmission between the stirring pin groups is not limited to the gear mesh transmission, and may be a belt transmission or a synchronous belt transmission.

Preferably, the mounting tray 42 includes a bottom case 421 and an upper cover 422. The bottom case 421 is connected to the ball spline shaft 22, the bottom case 421 has a receiving chamber in which the driving gear 412 and the driven gear group 413 are disposed, and the agitating pin 414 is located outside the receiving chamber. The upper cover 422 is connected with the bottom case 421 to seal the receiving chamber, and the agitation driving motor 411 is connected with the upper cover 422. The number of the driven gear sets 413 is plural, the plural driven gear sets 413 are arranged at intervals along the circumferential direction of the mounting disk 42, and each driven gear set 413 is provided with a stirring pin 414. The arrangement can enable a plurality of stirring cleaning operations to be carried out at the same time, and the efficiency of the stirring cleaning device is effectively improved. A plurality of stirring needles can be used for uniformly mixing reaction solution in a plurality of reaction containers at a time, and a stirring device can be used for simultaneously performing uniformly mixing and cleaning two actions, so that the time is more sufficient, and the efficiency is more efficient. All the stirring pins are controlled by one drive, so that the consistency of the uniformly mixing conditions of all the stirring pins is ensured, and the energy-saving and environment-friendly effects are achieved. The anti-collision mechanism is arranged on the stirring device, so that the stirring device is limited to descend and stir only at the correct working position, the stirring needle is prevented from being damaged due to mistaken collision, and the stirring device is safer and more reliable. The anti-collision mechanism 30 includes a positioning rod 31 and a positioning hole 32, the positioning hole 32 is opened on the bottom case 421 and the upper cover 422, and the positioning rod 31 is connected to the mounting seat for mounting the first vertical lifting mechanism 20.

Further, the detection module includes a first detection device 9 and a second detection device 10, the first detection device 9 is disposed on the rack and located inside the reaction module 15, the first detection device 9 is used for optically detecting an object to be detected in a reaction container on an inner ring of the reaction module 15, the second detection device 10 is disposed on the rack and located outside the reaction module 15, the second detection device 10 is located between the second stirring device 8 and the second reagent filling device 4, and the second detection device 10 is used for optically detecting an object to be detected in a reaction container on an outer ring of the reaction module 15. The first detection device 9 and the second detection device 10 are arranged at intervals of N reaction vessel accommodating positions along the rotation direction of the reaction disk, wherein N is greater than or equal to 3 and is a positive integer. Interference occurs during detection of the inner ring and the outer ring, and accuracy of detection results is improved. For example, the first detection device 9 is located at the accommodating position of the reaction vessel No. 1, and the second detection device 10 is located at the accommodating position of the reaction vessel No. 5, so that the mutual interference of the inner and outer reaction vessels of the reaction disk during optical detection can be avoided, and the accuracy of the detection result is affected.

The sample analyzer includes a cup-taking module located below the reaction module 15 for jacking up the reaction vessel to assist an operator in taking out the reaction vessel. The cup taking module comprises a drive part assembly, the drive part assembly comprises a drive part and a top cup part, the drive part is connected with the incubation disc, the top cup part is arranged on an output shaft of the drive part, and the drive part drives the top cup part to penetrate through the incubation disc to be below the accommodating position of the reaction vessel so as to eject the reaction vessel to the cup taking position. Wherein, the top cup part can be a screw rod.

In the counterclockwise direction of the reaction module 15, starting from a test start position 110 of the reaction module 15, the reaction module is sequentially provided with a second reagent filling position 2a, a second detection position 10a, a first detection position 9a, a second stirring position 8a, a first sample filling position 12a, a second sample filling position 11a, a first stirring position 7a, a first reagent filling position 3a, a washing solution stirring position 1a, a cup taking position 120, and cleaning positions (61a, 62a), and the cleaning module 6 includes an inner ring cleaning mechanism 61 and an outer ring cleaning mechanism 62.

The first sample filling device 11 is arranged on the frame, and the first sample filling device 11 is positioned between the first stirring device 7 and the second stirring device 8. A second sample filling device 12 is arranged on the rack, and the second sample filling device 12 is located between the first sample filling device 11 and the second stirring device 8. The first sample filling device 11 and the second sample filling device 12 are used for adding sample reagents into the reaction cups respectively.

Further, the electrolyte module 13 is disposed on the frame outside the first stirring device 7. The incubation module sets up in the frame, and the incubation module is used for providing the constant temperature reaction environment to the reaction cup in the reaction module 15, and the incubation module can also play the effect of putting is got in the reaction cup of automatic supplementary getting. The control module 16 is disposed on the rack and located outside the second stirring device 8, and the control module 16 is configured to control each module of the sample analyzer to perform a sample analysis and detection test. The electrolyte module 13 is an electrolyte module capable of measuring a plurality of ions simultaneously.

It is understood that the structure of the first reagent filling device 3 and the structure of the second reagent filling device 4 may be identical, the structure of the first sample filling device 11 and the structure of the second sample filling device 12 may be identical, the structure of the first stirring device 7 and the structure of the second stirring device 8 may be identical, and the structure of the first detecting device 9 and the structure of the second detecting device 10 may be identical.

Regarding reagent filling devices, three reagent filling devices are provided in the prior art, which have the following limitations: the prior art also provides a reagent filling device which performs X, Y and Z three-dimensional movement, and the reagent filling device can take samples and reagents at any positions in a rectangular area. But also has large volume, occupies larger plane layout area of the instrument and is not beneficial to the layout of the whole machine. And the structure is complex, the software control is easy to make mistakes, the cost is high, and the popularization and the application are not easy.

In order to solve the problem of large occupied area of the reagent filling device of the sample analyzer in the prior art, as shown in fig. 6, the reagent filling device in the present application includes a base 50, a horizontal rotating assembly 60, a second vertical lifting assembly 70 and a cantilever assembly 80. Wherein, the horizontal rotating assembly 60 is connected with the base 50, the second vertical lifting assembly 70 is connected with the horizontal rotating assembly 60 and also connected with the base 50, and the second vertical lifting assembly 70 can move in the vertical direction relative to the base 50. The cantilever assembly 80 is connected to the second vertical lifting assembly 70, and the second vertical lifting assembly 70 can drive the cantilever assembly 80 to move in the vertical direction. And the cantilever assembly 80 is rotatably disposed with respect to the second vertical elevating assembly 70, a projection of a rotation center of the cantilever assembly 80 on a horizontal plane is located in the reagent disk 1, and the cantilever assembly 80 is used for adding the reagent in the reagent disk 1 into the reaction cup in the reaction disk 2. By optimizing the structure of the reagent filling device of the sample analyzer, the reagent filling device is provided with a horizontal rotating component 60, a second vertical lifting component 70 and a cantilever component 80, wherein the cantilever component 80 is connected with the second vertical lifting component 70 and the horizontal rotating component 60, the cantilever component 80 can rotate relative to the second vertical lifting component 70, and the projection of the rotation center of the cantilever component 80 on the horizontal plane is positioned in the reagent disk 1, so that on one hand, in the process that the cantilever component 80 adds the reagent in the reagent disk 1 into the reaction cup in the reaction disk 2, the addition of the reagent can be realized by only rotating the cantilever component 80 by a small angle, and the rotation angle of the cantilever component 80 is greatly reduced; on the other hand, the arm length of the cantilever assembly 80 is reduced, so that the compact design of the reagent filling device is facilitated, the overall volume of the reagent filling device is ensured to be smaller, and the reagent filling device is ensured not to occupy larger installation space; in addition, the rotation angle of the cantilever assembly 80 is small, so that the requirement on the motion load of the motor can be reduced in the limited sample adding period of the sample analyzer.

It should be noted that, in this application, the cantilever subassembly is concentrated together, very big reduction installation space, the cantilever subassembly height dislocation and the design of long and short arm, a plurality of arm subassemblies move mutually independent in horizontal direction and vertical direction like this, all can arrive reagent dish inner and outer lane and absorb reagent, can not mutual interference, and the work efficiency is improved, and the rotation center is located the outside, so only need rotate less angle alright in order to realize the interpolation of reagent, the rotation angle of cantilever subassembly has been reduced greatly, and the occupation space is reduced.

Spatially relative terms, such as "above … …," "above … …," "above … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial relationship to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if a device in the figures is turned over, devices described as "above" or "on" other devices or configurations would then be oriented "below" or "under" the other devices or configurations. Thus, the exemplary term "above … …" can include both an orientation of "above … …" and "below … …". The device may be otherwise variously oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

In addition to the foregoing, it should be noted that reference throughout this specification to "one embodiment," "another embodiment," "an embodiment," or the like, means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment described generally throughout this application. The appearances of the same phrase in various places in the specification are not necessarily all referring to the same embodiment. Further, when a particular feature, structure, or characteristic is described in connection with any embodiment, it is submitted that it is within the scope of the invention to effect such feature, structure, or characteristic in connection with other embodiments.

In the foregoing embodiments, the descriptions of the respective embodiments have respective emphasis, and for parts that are not described in detail in a certain embodiment, reference may be made to related descriptions of other embodiments.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (17)

1. A sample analyzer, comprising:

the frame, be provided with the reagent storage module of storage reagent in the frame, be used for the suction and discharge sample or the branch injection module of reagent, be used for bearing reaction vessel reagent and sample reaction's reaction module (15), be used for carrying out the detection module that detects to the sample after the reaction and be used for carrying out abluent washing module (6) to the reaction vessel after detecting the completion, the frame has the operation side towards the operator, reaction module (15) set up in the middle part position department of frame, reagent storage module includes at least two and above reagent storage device, and is a plurality of reagent storage device set up in the frame, and it is a plurality of reagent storage device all is close to operator one side sets up, and is a plurality of reagent storage device follows the circumference setting of reaction module (15).

2. The sample analyzer as claimed in claim 1, wherein the reaction module (15) comprises a rotatable and disk-shaped reaction disk, the reaction disk being provided with at least two inner and outer circles of reaction vessel receiving locations in which the reaction vessels are placed, each circle comprising a plurality of reaction vessel receiving locations.

3. The sample analyzer of claim 1, wherein the reaction module (15) further comprises an incubation tray (14), the incubation tray (14) being located below the reaction tray for providing a constant temperature reaction environment for the reagents and the sample within the reaction vessel.

4. The sample analyzer as claimed in claim 1, characterized in that the reagent storage module comprises a first reagent storage device (1) and a second reagent storage device (2), the first reagent storage device (1) and the second reagent storage device (2) being used for placing different types of reagents.

5. The sample analyzer as claimed in claim 4, characterized in that the first reagent storage device (1) is placed on the left side of the operating side, the second reagent storage device (2) is placed on the right side of the operating side, and the reaction module (15) is placed between the first reagent storage device (1) and the second reagent storage device (2) and is located away from the operator.

6. The sample analyzer of claim 4 wherein the reagent storage module comprises a rotatable disk-shaped reagent disk capable of storing a plurality of reagents, the reagent disk comprising at least two inner and outer circles of reagent storage locations.

7. The sample analyzer of claim 4,

the dispensing module is used for transferring a sample to the reaction container of the reaction module, and the dispensing module is also used for transferring a reagent in the reagent storage module to the reaction container of the reaction module;

the dispensing module comprises a first reagent filling device (3) and a second reagent filling device (4), wherein the first reagent filling device (3) is used for transferring the reagent in the first reagent storage device (1), and the second reagent filling device (4) is used for transferring the reagent in the second reagent storage device (2);

the first reagent filling device (3) is arranged between the first reagent storage device (1) and the reaction module, and the second reagent filling device (4) is arranged between the second reagent storage device (2) and the reaction module.

8. The sample analyzer of claim 7,

at least one of the first reagent filling device (3) and the second reagent filling device (4) is provided with two reagent arms capable of independently moving, the two reagent arms are arranged along the vertical direction in a staggered mode, each reagent arm can move along the vertical direction and can rotate along the horizontal direction, one of the two reagent arms is used for adding reagents to reaction containers located on the inner ring, and the other reagent arm is used for adding reagents to reaction containers located on the outer ring.

9. The sample analyzer as claimed in claim 7, characterized in that the washing module (6) comprises:

and the washing liquid stirring device (5), the washing liquid stirring device (5) and the first reagent filling device (3), the first reagent storage device (1) and the reaction module (15) are adjacently arranged, and the washing liquid stirring device (5) is used for stirring the reaction container after the detection is finished when the reaction container is cleaned.

10. The sample analyzer of claim 9,

the cleaning module (6) is arranged adjacent to the reaction module (15), the cleaning module (6) is arranged between the first reagent filling device (3) and the second reagent filling device (4) and close to the operation side, and the cleaning module (6) is used for cleaning a reaction container in the reaction module (15).

11. The sample analyzer of claim 4, further comprising:

a stirring module comprising a first stirring device (7) and a second stirring device (8), wherein the first stirring device (7) and the second stirring device (8) are both arranged adjacent to the reaction module (15) and are used for stirring the sample and the reagent in the reaction container so as to enable the sample and the reagent to fully react;

at least one of the first stirring device (7) and the second stirring device (8) is provided with three groups of stirring arms, and each group of stirring arms can move along the vertical direction and can also rotate along the horizontal direction.

12. The sample analyzer of claim 11,

at least one set of the stirring arms are provided with two stirring pins which are respectively used for stirring the inner ring and the outer ring of the reaction module (15), wherein when the stirring pins of one set of the stirring arms are used for stirring, the stirring pins of the other two sets of the stirring arms can be used for cleaning.

13. The sample analyzer as claimed in claim 12, wherein the detection module comprises a first detection device (9) and a second detection device (10), the first detection device (9) is disposed on the rack and located inside the reaction module (15), the first detection device (9) is used for optically detecting the analyte in the reaction container on the inner ring of the reaction module (15), the second detection device (10) is disposed on the rack and located outside the reaction module (15), the second detection device (10) is located between the second stirring device (8) and the second reagent filling device (4), and the second detection device (10) is used for optically detecting the analyte in the reaction container on the outer ring of the reaction module (15).

14. The sample analyzer of claim 13,

the first detection device (9) and the second detection device (10) are arranged at intervals of N reaction container accommodating positions along the rotation direction of the reaction disk, wherein N is more than or equal to 3 and is a positive integer.

15. The sample analyzer of claim 7, wherein the sample analyzer comprises:

a cup taking module located below the reaction module (15) for jacking up the reaction vessel to assist an operator in taking out the reaction vessel.

16. The sample analyzer of claim 15, wherein the cup taking module comprises: and the drive part assembly comprises a drive part and a top cup part, the drive part is connected with the incubation disk, the top cup part is arranged on an output shaft of the drive part, and the drive part drives the top cup part to penetrate through the incubation disk to be below the reaction container accommodating position so as to eject the reaction container to a cup taking position.

17. The sample analyzer as claimed in claim 1, wherein a second reagent filling position, a second detection position, a first detection position, a second stirring position, a first sample filling position, a second sample filling position, a first stirring position, a first reagent filling position, a washing solution stirring position, a cup taking position (120) and a cleaning position are sequentially arranged on the reaction module (15) from a test starting position (110) of the reaction module (15) in a counterclockwise direction of the reaction module (15), and the cleaning module (6) comprises an inner ring cleaning mechanism (61) and an outer ring cleaning mechanism (62).

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