CN214066676U - Uncovering-free automatic separating device - Google Patents

Uncovering-free automatic separating device Download PDF

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Publication number
CN214066676U
CN214066676U CN202023228558.5U CN202023228558U CN214066676U CN 214066676 U CN214066676 U CN 214066676U CN 202023228558 U CN202023228558 U CN 202023228558U CN 214066676 U CN214066676 U CN 214066676U
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China
Prior art keywords
uncapping
sample bottle
barrel
free
separating apparatus
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CN202023228558.5U
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Chinese (zh)
Inventor
詹晓春
詹斯喻
付凤霞
张海燕
王静
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Zhengzhou Zhongpu Medical Equipment Co ltd
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Zhengzhou Zhongpu Medical Equipment Co ltd
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Abstract

The utility model relates to an automatic separation device without opening cover, which comprises a lower barrel and an upper barrel, wherein the upper barrel and the lower barrel are inserted and matched up and down, a filter screen is arranged in the upper barrel, a filter membrane is arranged in the lower barrel, and the filter screen is positioned above the filter membrane; the upper part of the upper barrel body is provided with a thread structure for installing the uncapping-free sample bottle in a thread manner, and the upper barrel body is internally provided with a poking-breaking structure for poking-breaking the end part of the uncapping-free sample bottle in the installation process of the uncapping-free sample bottle so as to enable sample liquid to flow downwards. Adopt this neotype exempt from to uncap autosegregation device, among the cell separation process, the sample bottle exempts from to uncap to the artifical mode of pouring the sample liquid, the operation of being convenient for, the sample liquid does not expose in the air moreover, can improve the security.

Description

Uncovering-free automatic separating device
Technical Field
The utility model relates to a cell separation technical field, concretely relates to exempt from uncap autosegregation device.
Background
A filter (i.e., a separating device) is required to separate the cells from the cell retaining fluid and adhere the cells to the slide during the process of completing the exfoliated cell smear using the liquid-based cell automatic slide-making apparatus.
The utility model discloses a filter suitable for among automatic film-making equipment of liquid base cell as utility model patent of grant publication No. CN209727578U, it includes filter epitheca, filter screen, filtration membrane, filter inferior valve. The filter upper shell is internally provided with a liquid storage cavity for storing specimen base liquid. The filter screen sets up the intermediate position in filtering the shell for filter the impurity in the sample base fluid. Filter membrane sets up in the inside upper end of filter inferior valve, and filter membrane is located the sponge upper end, and filter membrane is used for filtering the cell. When the cell adsorption filter is used, specimen base liquid is required to be poured into the liquid storage cavity, and then the cells meeting the conditions can be adsorbed on the filter membrane after being sequentially filtered by the filter screen and the filter membrane under negative pressure. The pouring of the specimen liquid requires opening the specimen bottle of the specimen liquid, and some samples of patients may have germs in the air and cause pollution.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing an exempt from to uncap autosegregation device to solve foretell need the manual work and pour into the sample liquid and expose the technical problem in the air.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the cover-opening-free automatic separation device comprises a lower barrel and an upper barrel, wherein the upper barrel and the lower barrel are vertically inserted and matched, a filter screen is arranged in the upper barrel, a filter membrane is arranged in the lower barrel, and the filter screen is positioned above the filter membrane; the upper part of the upper barrel body is provided with a thread structure for installing the uncapping-free sample bottle in a thread manner, and the upper barrel body is internally provided with a poking-breaking structure for poking-breaking the end part of the uncapping-free sample bottle in the installation process of the uncapping-free sample bottle so as to enable sample liquid to flow downwards.
Further, barrel upper portion is equipped with filtration membrane bearing structure down, and filtration membrane bearing structure includes the support otter board and is located the sponge layer on the support otter board, filtration membrane is located the upside on sponge layer.
Further, the poking and breaking structure comprises a supporting seat and a conical tip positioned at the upper part.
Further, the cross section of the supporting seat is in a cross shape.
Furthermore, the lower end of the uncapping-free sample bottle is provided with a disposable sealing cover, the upper part of the uncapping-free sample bottle is provided with a detachable bottle cap, and the disposable sealing cover can be poked and broken by the poking and breaking structure.
Further, the disposable sealing cover adopts aluminum foil paper or a thin film.
Further, the lower end of the uncapping-free sample bottle is a necking part, and a threaded connecting part is arranged on the periphery of the necking part of the uncapping-free sample bottle and used for being connected with the upper barrel.
Furthermore, the threaded connection portion adopts internal threads, and the periphery of the upper barrel body is provided with corresponding internal threads.
Furthermore, the uncapping-free sample bottle is provided with a communication hole at the position of the threaded connection part for communicating the inside and the outside of the upper cylinder body.
Furthermore, the inner wall of the lower part of the upper cylinder body is provided with a positioning groove, and the periphery of the lower cylinder body is provided with a positioning bulge corresponding to the positioning groove.
The utility model has the advantages that:
the utility model discloses autosegregation device exempts from to uncap is equipped with the sample bottle of exempting from to uncap for gather sample liquid in advance. When separation, film-making, the one end that will exempt from to uncap sample bottle is down, and the spiral is twisted on last barrel upper portion, and the in-process of twisting, this tip of exempting from to uncap sample bottle can be punctured to the meeting of the structure of stabbing in the last barrel and get into, and the negative pressure of taking out of barrel under the cooperation simultaneously, sample liquid can be by exempting from to uncap sample bottle in along stabbing the structure and flow into last barrel, carries out the coarse filtration through the filter screen, then further flow to filtration membrane, will need the cell adhesion of separation in filtration membrane department. The next slide preparation process is similar to the operation in the prior art, the filter membrane is contacted with the slide, the cells on the filter membrane are adhered to the slide, cell transfer is realized, and the slide preparation is completed. Adopt this neotype exempt from to uncap autosegregation device, among the cell separation process, the sample bottle exempts from to uncap to the artifical mode of pouring the sample liquid, the operation of being convenient for, the sample liquid does not expose in the air moreover, can improve the security, prevents cross contamination.
Furthermore, the uncapping-free sample bottle is provided with the communicating hole, the internal pressure and the external pressure are balanced, the downward outflow of sample liquid is facilitated, and the separation effect is improved.
Drawings
FIG. 1 is a schematic view of the cover-opening free automatic separation device of the present invention;
fig. 2 is a cross-sectional view of the uncapping-free automatic separation device of the invention (the poking-breaking structure extends into an uncapping-free sample bottle);
FIG. 3 is a schematic view of the upper barrel at the breaking structure;
FIG. 4 is a schematic structural view of the lower cylinder;
fig. 5 is a schematic structural view of a uncapped sample vial.
Names corresponding to the marks in the figure:
1. the sample bottle comprises a sample bottle without being uncovered, 11, a bottle cap, 12, a communication hole, 13, a necking part, 14, a threaded connection part, 15, a disposable sealing cover, 2, an upper barrel, 21, a positioning boss, 3, a lower barrel, 31, a positioning installation block, 32, a positioning bulge, 4, a poking structure, 5, a filter screen, 6 and a filter membrane.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art all belong to the protection scope of the present invention.
The embodiment of the utility model provides a:
as shown in fig. 1-5, the uncapping-free automatic separation device comprises a lower cylinder 3 and an upper cylinder 2, wherein the upper cylinder 2 and the lower cylinder 3 are inserted and matched up and down, a filter screen 5 is arranged in the upper cylinder 2, a filter membrane 6 is arranged in the lower cylinder 3, and the filter screen 5 is positioned above the filter membrane 6. A filter screen 5 for coarse filtering of the sample liquid, such as filtering of residues therein; a filtration membrane for filtering cells, etc., and leaving the cells to be separated at the filtration membrane. The filter screen 5 and the filter membrane 6 are similar to those of the prior art. The inner wall of the upper cylinder 2 is provided with a step for supporting the filter screen.
3 upper portions of barrel are equipped with filtration membrane bearing structure down, and filtration membrane bearing structure is including supporting the otter board and being located the sponge layer on the support otter board, and filtration membrane is located the upside on sponge layer. The sponge layer has a plurality of through-hole structures, and the sample liquid after being convenient for to filter flows downwards, and the sponge layer supports filtration membrane, and under the negative pressure effect, filtration membrane is difficult to be destroyed, sets up the sponge layer moreover after, also be convenient for the epilogue shift to on the glass with the adsorbed cell of filtration membrane.
The inner wall of the lower part of the upper barrel body 2 is provided with a positioning groove, the periphery of the lower barrel body 3 is provided with a positioning bulge 32 corresponding to the positioning groove, and the positioning groove and the positioning bulge extend in the axial direction of the upper barrel body or the lower barrel body.
The periphery of lower barrel 3 is equipped with location installation piece 31, and the periphery of upper barrel 2 is equipped with a plurality of along the location boss 21 of circumference distribution, all is used for when the installation with the corresponding structure cooperation of automatic film-making equipment.
The utility model discloses a main improvement lies in:
go up the upper portion of barrel 2 and be equipped with the helicitic texture for the screw thread installation exempts from to uncap sample bottle 1, go up and be equipped with in the barrel 2 and disclose brokenly structure 4 for the tip of disclosing to exempt from to uncap sample bottle in exempting from to uncap sample bottle installation so that sample liquid flows down. The breaking structure 4 comprises a supporting seat and a conical tip positioned at the upper part. The cross section of the supporting seat is in a cross shape, and the conical tip is also in a cross shape.
The lower end part of the uncapping-free sample bottle 1 is provided with a disposable sealing cover 15, the upper part of the uncapping-free sample bottle is provided with a detachable bottle cap 11, and the disposable sealing cover can be poked and broken by the poking and breaking structure. The disposable sealing cover is made of aluminum foil paper or other films, or the disposable sealing cover of the uncapping-free sample bottle is thin, and the sample bottle body is made of the same material and is made to be thinner, and can be punctured by the puncturing structure with the conical tip.
The lower end of the uncapping-free sample bottle 1 is a throat portion 13, and a screw connection portion 14 for connecting to the upper cylinder 2 is provided on the outer periphery of the throat portion of the uncapping-free sample bottle. This threaded connection portion is along the tube-shape of this sample bottle downwardly extending, and the bottom is provided with the internal thread, and the internal thread cooperation that corresponds that sets up with the periphery of last barrel 2 realizes exempting from to uncap being connected of sample bottle 1 and last barrel 2.
The screw thread connecting part of the uncapping-free sample bottle is provided with a communicating hole 12, and the communicating hole 12 is positioned at the upper side of the internal thread and is used for communicating the inside and the outside of the upper cylinder body 2.
The bottle cap 11 at the upper part of the uncapping-free sample bottle is also assembled in a spiral mode, and during sampling, for example, sputum of a patient is taken, the bottle cap is opened, and the bottle cap is screwed after the sputum is taken, so that the taken sample liquid is not exposed to the air.
The utility model discloses an exempt from to uncap autosegregation device's principle summary explains as follows:
exempt from to uncap sample bottle 1 for gather sample liquid in advance, open detachable bottle lid 11 can, cover the bottle lid after finishing, guarantee not expose in the air. In the separation, during the film-making, the disposable closing cap 15's of exempting from to uncap sample bottle one end is down, the spiral is twisted on last barrel 2 upper portion, the in-process of twisting, the disposable closing cap that exempting from to uncap sample bottle can be punctured and get into to the awl point of the broken structure 4 in the last barrel 2, the suction pressure of barrel under the cooperation simultaneously, sample liquid can be by exempting from to uncap sample bottle in along stabbing the broken structure inflow last barrel 2, carry out the coarse filtration through filter screen 5, then further flow to filtration membrane 6, filtration membrane 6's aperture sets up to accord with and sets up the requirement, the cell that will need the separation is stayed in filtration membrane department, adsorb on filtration membrane surface. The uncapping-free sample bottle is provided with a communicating hole, which is beneficial to the downward flow of sample liquid. Next, similarly to the operation in the prior art, the lower cylinder is detached downward relative to the upper cylinder 2, the filter membrane is exposed, the slide is horizontally inserted above the filter membrane, and the lower cylinder is moved upward by a set distance so that the filter membrane contacts the slide, and the cells thereon are adhered to the slide, thereby realizing cell transfer and completing slide production. In the process, the sample bottle is free from opening the cover, so that the operation is convenient, the sample liquid is not exposed in the air, the safety can be improved, the air is not polluted, and the sample is also prevented from being polluted.
In other embodiments, the point of the piercing structure may be a non-cruciform, such as a trident, i.e. three support plates circumferentially spaced 120, tapered at the top.
In other embodiments, the bottom of the sample bottle is free from being uncovered, and an external thread can be arranged and matched with the corresponding internal thread of the upper cylinder body, so that the screw assembly of the sample bottle and the upper cylinder body is realized.

Claims (10)

1. The cover-opening-free automatic separation device comprises a lower barrel and an upper barrel, wherein the upper barrel and the lower barrel are vertically inserted and matched, a filter screen is arranged in the upper barrel, a filter membrane is arranged in the lower barrel, and the filter screen is positioned above the filter membrane; the method is characterized in that: the upper part of the upper barrel body is provided with a thread structure for installing the uncapping-free sample bottle in a thread manner, and the upper barrel body is internally provided with a poking-breaking structure for poking-breaking the end part of the uncapping-free sample bottle in the installation process of the uncapping-free sample bottle so as to enable sample liquid to flow downwards.
2. The uncapping automatic separating apparatus according to claim 1, wherein: lower barrel upper portion is equipped with filtration membrane bearing structure, and filtration membrane bearing structure includes the support otter board and is located the sponge layer on the support otter board, filtration membrane is located the upside on sponge layer.
3. The uncapping automatic separating apparatus according to claim 1, wherein: the poking and breaking structure comprises a supporting seat and a conical tip positioned at the upper part.
4. The uncapping automatic separating apparatus according to claim 3, wherein: the cross section of the supporting seat is in a cross shape.
5. The uncapping automatic separating apparatus according to claim 1, wherein: the lower end part of the uncapping-free sample bottle is provided with a disposable sealing cover, the upper part of the uncapping-free sample bottle is provided with a detachable bottle cap, and the disposable sealing cover can be poked and broken by the poking and breaking structure.
6. The uncapping automatic separating apparatus according to claim 5, wherein: the disposable sealing cover adopts aluminum foil paper or thin film.
7. The uncapping automatic separating apparatus according to claim 5, wherein: the lower end of the uncapping-free sample bottle is a necking part, and a threaded connecting part is arranged on the periphery of the necking part of the uncapping-free sample bottle and is used for being connected with the upper barrel.
8. The uncapping automatic separating apparatus according to claim 7, wherein: the threaded connection part adopts internal threads, and the periphery of the upper barrel body is provided with corresponding internal threads.
9. The uncapping automatic separating apparatus according to claim 8, wherein: the sample bottle without opening the cover is provided with a communicating hole at the position of the threaded connecting part for communicating the inside and the outside of the upper cylinder body.
10. The uncap-free automatic separation apparatus according to any one of claims 1 to 9, wherein: and a positioning groove is formed in the inner wall of the lower part of the upper barrel, and a positioning bulge corresponding to the positioning groove is formed in the periphery of the lower barrel.
CN202023228558.5U 2020-12-25 2020-12-25 Uncovering-free automatic separating device Active CN214066676U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202023228558.5U CN214066676U (en) 2020-12-25 2020-12-25 Uncovering-free automatic separating device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202023228558.5U CN214066676U (en) 2020-12-25 2020-12-25 Uncovering-free automatic separating device

Publications (1)

Publication Number Publication Date
CN214066676U true CN214066676U (en) 2021-08-27

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Application Number Title Priority Date Filing Date
CN202023228558.5U Active CN214066676U (en) 2020-12-25 2020-12-25 Uncovering-free automatic separating device

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CN (1) CN214066676U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114018673A (en) * 2021-11-29 2022-02-08 郑州中普医疗器械有限公司 Separation film-making all-in-one
CN115876551A (en) * 2022-12-20 2023-03-31 杭州迪安生物技术有限公司 Cell film-making of high filterability is with filtration membrane section of thick bamboo

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114018673A (en) * 2021-11-29 2022-02-08 郑州中普医疗器械有限公司 Separation film-making all-in-one
CN115876551A (en) * 2022-12-20 2023-03-31 杭州迪安生物技术有限公司 Cell film-making of high filterability is with filtration membrane section of thick bamboo
CN115876551B (en) * 2022-12-20 2023-08-11 杭州迪安生物技术有限公司 Cell film-making of high filterability is with filtration membrane section of thick bamboo

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