CN210741954U - Simple liquid-based cell slide-making assembly - Google Patents

Simple liquid-based cell slide-making assembly Download PDF

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CN210741954U
CN210741954U CN201721580108.8U CN201721580108U CN210741954U CN 210741954 U CN210741954 U CN 210741954U CN 201721580108 U CN201721580108 U CN 201721580108U CN 210741954 U CN210741954 U CN 210741954U
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filter
cup
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liquid
cup body
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吴红军
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Abstract

The utility model discloses a simple and easy liquid-based cell film-making subassembly, comprising a cup body, the detachable cover in the cup have filter cup, the cup on be equipped with detachable filter head and detachable film-making head in proper order, still can form a complete set one with the sealed lid that the cup matches. The utility model discloses can collect the sample, centrifugal filtration, enrichment sediment cell is in accomplishing integratively, and the centre need not to change the appearance cup again, and filtration after the coarse filtration and enrichment sediment cell are one step accomplished, only need manual lid cell tissue on the slide can.

Description

一种简易液基细胞制片组件A simple liquid-based cell preparation component

【技术领域】【Technical field】

本实用新型涉及一种简易液基细胞制片组件,属于医用检测辅助设备技术领域。The utility model relates to a simple liquid-based cell preparation assembly, which belongs to the technical field of medical detection auxiliary equipment.

【背景技术】【Background technique】

目前医疗上的液基细胞标本制片大多为手工操作或自动化制片,但手工操作,步骤复杂,用时长,不够方便快捷,而自动化制片比较适用于大批量标本制片,对于个别标本制片不够经济,相对于手工操作更加耗时。At present, most liquid-based cell specimen preparations in medical treatment are manual or automated, but manual operations are complicated, time-consuming, and not convenient and fast. Automated preparation is more suitable for large-volume specimen preparation. Slices are not economical and are more time-consuming than manual operations.

【实用新型内容】【Content of utility model】

本实用新型目的是克服现有技术的缺陷,提供一种适用于手工操作且方便快捷的简易液基细胞制片组件。The purpose of the utility model is to overcome the defects of the prior art and provide a simple and convenient liquid-based cell preparation assembly suitable for manual operation.

本实用新型是通过以下技术方案实现的:The utility model is achieved through the following technical solutions:

一种简易液基细胞制片组件,其特征在于包括杯体,所述的杯体内可分离地套有过滤杯,所述的杯体上依次设有可拆卸的过滤头和可拆卸的制片头。A simple liquid-based cell tableting assembly is characterized in that it comprises a cup body, a filter cup is detachably sheathed in the cup body, and a detachable filter head and a detachable tablet are arranged on the cup body in turn. head.

如上所述的一种简易液基细胞制片组件,其特征在于所述的过滤杯底部为过滤网,所述过滤网与所述杯体的底部有间隙。The above-mentioned simple liquid-based cell tablet assembly is characterized in that the bottom of the filter cup is a filter screen, and there is a gap between the filter screen and the bottom of the cup body.

如上所述的一种简易液基细胞制片组件,其特征在于所述的过滤头包括与所述杯体可拆卸连接的过滤盖,所述的过滤盖上设有过滤层,所述的过滤盖上设有与所述杯体内相通的过滤孔。A simple liquid-based cell tablet assembly as described above, characterized in that the filter head comprises a filter cover detachably connected to the cup body, the filter cover is provided with a filter layer, and the filter The cover is provided with filter holes communicated with the cup body.

如上所述的一种简易液基细胞制片组件,其特征在于所述的制片头包括可拆卸连接在所述过滤头上的制片盖,所述的制片盖外设有与所述制片盖内相通的出口管,所述的出口管连接负压,所述制片盖上设有凸出于其端面的缓冲垫和覆盖所述缓冲垫的细胞沉淀膜。A simple liquid-based cell tableting assembly as described above, characterized in that the tableting head comprises a tableting cover detachably connected to the filter head, and the tableting cover is externally provided with the The outlet pipe communicated in the tablet cover, the outlet pipe is connected with negative pressure, and the tablet cover is provided with a buffer pad protruding from its end surface and a cell sedimentation membrane covering the buffer pad.

如上所述的一种简易液基细胞制片组件,其特征在于所述的过滤头和制片头之间设有可拆卸的过滤筒,所述的过滤筒上设有至少一个过滤片。A simple liquid-based cell tableting assembly as described above is characterized in that a detachable filter cartridge is arranged between the filter head and the tableting head, and at least one filter disc is arranged on the filter cartridge.

如上所述的一种简易液基细胞制片组件,其特征在于所述杯体的内腔为锥形腔,所述过滤杯的底部为平面过滤网。The above-mentioned simple liquid-based cell tableting assembly is characterized in that the inner cavity of the cup body is a conical cavity, and the bottom of the filter cup is a flat filter screen.

如上所述的一种简易液基细胞制片组件,其特征在于所述杯体的外周为筒状,所述的杯体底部端面为平面。The above-mentioned simple liquid-based cell tableting assembly is characterized in that the outer periphery of the cup body is cylindrical, and the bottom end surface of the cup body is flat.

如上所述的一种简易液基细胞制片组件,其特征在于所述过滤杯的内周壁上径向设有凹槽。The above-mentioned simple liquid-based cell tableting assembly is characterized in that grooves are radially provided on the inner peripheral wall of the filter cup.

如上所述的一种简易液基细胞制片组件,其特征在于所述的凹槽为环形。The above-mentioned simple liquid-based cell tablet assembly is characterized in that the groove is annular.

如上所述的一种简易液基细胞制片组件,其特征在于所述的凹槽为多段弧形槽,在同一径向平面上环向分布。The above-mentioned simple liquid-based cell tablet assembly is characterized in that the grooves are multi-segment arc-shaped grooves, which are circumferentially distributed on the same radial plane.

与现有技术相比,本实用新型有如下优点:Compared with the prior art, the utility model has the following advantages:

本实用新型中,杯体内的过滤杯放入带有液基细胞的标本刷后,离心过滤后,取出过滤杯,将过滤头或过滤头与过滤筒的组合连接在杯体上,再盖上制片头,通过注射管或负压泵连接制片头上的出口管抽真空,杯体内细胞液基进入负压设备,细胞组织留在制片头上,在玻片上盖印转移细胞组织即可制片。In the utility model, after the filter cup in the cup body is put into the specimen brush with liquid-based cells, after centrifugal filtration, the filter cup is taken out, the filter head or the combination of the filter head and the filter cartridge is connected to the cup body, and then covered The production head is connected to the outlet pipe on the production head through a syringe or a negative pressure pump to vacuumize, the cell liquid base in the cup enters the negative pressure equipment, the cell tissue remains on the production head, and the transferred cell tissue is stamped on the glass slide. Can be filmed.

本实用新型可以集取样,离心过滤,富集沉淀细胞于一体地完成,中间无需再更换样杯,粗过滤后的过滤与富集沉淀细胞一步完成,只需手工盖细胞组织在玻片上即可。The utility model can complete sampling, centrifugal filtration, and enrichment and sedimentation cells in one body, without the need to replace the sample cup in the middle, the filtration after coarse filtration and the enrichment of sedimentary cells are completed in one step, and it is only necessary to manually cover the cell tissue on the glass slide. .

本实用新型结构简单,使用方便,适于推广。The utility model has the advantages of simple structure and convenient use, and is suitable for popularization.

【附图说明】【Description of drawings】

图1是本实用新型的立体结构示意图;Fig. 1 is the three-dimensional structure schematic diagram of the present utility model;

图2是本实用新型的爆炸结构示意图;Fig. 2 is the exploded structure schematic diagram of the present utility model;

图3是本实用新型过滤头、制片头和过滤筒的爆炸结构示意图;Fig. 3 is the exploded structure schematic diagram of filter head, tablet head and filter cartridge of the present utility model;

图4是杯体和过滤杯的爆炸结构示意图。Figure 4 is a schematic diagram of the exploded structure of the cup body and the filter cup.

【具体实施方式】【Detailed ways】

下面结合说明书附图对本实用新型作进一步说明:The utility model is further described below in conjunction with the accompanying drawings of the description:

如图1-4所示,一种简易液基细胞制片组件,包括杯体1,杯体1内可分离地套有过滤杯2,杯体1上依次设有可拆卸的过滤头3和可拆卸的制片头4。As shown in Figures 1-4, a simple liquid-based cell preparation assembly includes a cup body 1, a filter cup 2 is detachably sheathed in the cup body 1, and a detachable filter head 3 and a detachable filter head 3 and Detachable tablet head 4.

进一步地,过滤杯2底部21为过滤网,过滤网与杯体1的底部有间隙。当然,过滤杯2的杯壁可以过滤也可以不过滤。Further, the bottom 21 of the filter cup 2 is a filter screen, and there is a gap between the filter screen and the bottom of the cup body 1 . Of course, the cup wall of the filter cup 2 may or may not be filtered.

过滤头3包括与杯体1可拆卸连接的过滤盖31,过滤盖31上设有过滤层32,过滤盖31上设有与杯体1内相通的过滤孔311,过滤层32优选设置在过滤孔311的出口方向上。The filter head 3 includes a filter cover 31 that is detachably connected to the cup body 1. The filter cover 31 is provided with a filter layer 32, and the filter cover 31 is provided with filter holes 311 that communicate with the cup body 1. in the direction of the exit of the hole 311 .

制片头4包括可拆卸连接在过滤头3上的制片盖41,制片盖41外设有与制片盖41内相通的出口管411,出口管411连接负压,制片盖41内侧设有凸出于制片盖41端面的缓冲垫42和覆盖缓冲垫42的细胞沉淀膜43。The tableting head 4 includes a tableting cover 41 that is detachably connected to the filter head 3. The tableting cover 41 is provided with an outlet pipe 411 that communicates with the tableting cover 41. The outlet pipe 411 is connected to negative pressure, and the inner side of the tableting cover 41 A buffer pad 42 protruding from the end surface of the tablet cover 41 and a cell sedimentation membrane 43 covering the buffer pad 42 are provided.

进一步地,过滤头3和制片头4之间设有可拆卸的过滤筒5,过滤筒5上设有至少一个过滤片51。过滤头3与杯体1,过滤头3与制片头4或与过滤筒5,过滤筒5与制片头均为可拆卸连接,可拆卸连接可以为螺接,也可以为卡接,密封不漏气不漏液即可。如果需要,也可以在过滤头3和制片头4之前加设多个过滤筒,形成逐级多层过滤。Further, a detachable filter cartridge 5 is provided between the filter head 3 and the tablet head 4 , and at least one filter sheet 51 is provided on the filter cartridge 5 . The filter head 3 and the cup body 1, the filter head 3 and the tableting head 4 or the filter cartridge 5, and the filter cartridge 5 and the tableting head are all detachably connected, and the detachable connection can be screwed or clamped. No leaks, no leaks. If necessary, multiple filter cartridges can also be added before the filter head 3 and the tablet head 4 to form a step-by-step multi-layer filter.

进一步地,杯体1的内腔11为锥形腔,过滤杯2的底部21为平面过滤网,与锥形腔之前形成一个富集液基细胞的空间,便于取样后直接离心,无需更换离心管,杯体1的外周12为筒状,所述的杯体1底部端面13为平面,也可以为环形平面,露出锥形腔外壳。Further, the inner cavity 11 of the cup body 1 is a conical cavity, and the bottom 21 of the filter cup 2 is a flat filter screen, which forms a space for enriching liquid-based cells before the conical cavity, which is convenient for direct centrifugation after sampling, and no need to replace the centrifuge. Tube, the outer circumference 12 of the cup body 1 is cylindrical, the bottom end surface 13 of the cup body 1 is a plane, and it can also be an annular plane, exposing the conical cavity shell.

更进一步地,过滤杯2的内周壁上径向设有凹槽22,凹槽22可以为环形,也可以为多段弧形槽,在同一径向平面上环向分布。便于过滤后夹取出过滤杯2。Further, grooves 22 are radially provided on the inner peripheral wall of the filter cup 2 , and the grooves 22 may be annular or multi-segment arc-shaped grooves, which are distributed circumferentially on the same radial plane. It is convenient to take out the filter cup 2 after filtering.

制片时,先用宫颈刷类的样本刷取样,放入杯体1内的过滤杯2内,离心过滤后,取出过滤杯2,连接过滤头3和制片头4,需要多层过滤可以在过滤头3与制片头4之间连接过滤筒5,然后制片头4上的出口管411连接负压(注射管或负压泵),调转杯体1向上,抽真空,待制片盖41上的细胞沉淀膜43富集细胞后,停止负压,调转杯体1向下,拆下制片头4,将细胞沉淀膜43对准玻片盖印,即可转移细胞标本,完成制片。When producing, first use a sample brush such as a cervical brush to sample, put it into the filter cup 2 in the cup body 1, and after centrifugal filtration, take out the filter cup 2, and connect the filter head 3 and the production head 4. Multi-layer filtration can be used. Connect the filter cartridge 5 between the filter head 3 and the tableting head 4, and then connect the negative pressure (injection tube or negative pressure pump) to the outlet pipe 411 on the tableting head 4, turn the cup body 1 upward, vacuumize, and wait for tableting After the cell sedimentation membrane 43 on the cover 41 is enriched with cells, stop the negative pressure, turn the cup body 1 downward, remove the tablet head 4, align the cell sedimentation membrane 43 with the glass slide and stamp it, and then the cell specimen can be transferred, and finished. film.

本实用新型的另一个实施例,杯体1上还配有单独的密封盖,与过滤头3、制片头4替换,形成配套组件。批量制片时,杯体1内放入细胞组织样本后,先用密封盖盖住,制片时,再由制片人员将密封盖拧下,替换过滤头3和制片头4进行制片,密封盖即为一般的瓶盖即可。In another embodiment of the present invention, the cup body 1 is also provided with a separate sealing cover, which is replaced with the filter head 3 and the tablet head 4 to form a matching assembly. During batch production, after placing the cell tissue sample in the cup body 1, cover it with a sealing cap. When producing, the production staff will unscrew the sealing cap and replace the filter head 3 and the production head 4 for production. , the sealing cap is the general bottle cap.

Claims (8)

1. The utility model provides a simple and easy liquid-based cell film-making subassembly which characterized in that: including cup (1), cup (1) in detachable cover have filter cup (2), cup (1) on be equipped with detachable filter head (3) and detachable system piece head (4) in proper order, filter cup (2) bottom (21) be the filter screen, the filter screen with the bottom of cup (1) is gapped, system piece head (4) including can dismantle the connection in system piece lid (41) on filter head (3), system piece lid (41) be equipped with outward with communicating outlet pipe (411) in system piece lid (41), outlet pipe (411) connect injection pipe or negative pressure pump, be equipped with on system piece lid (41) bump in the blotter (42) of its terminal surface and cover the cell sedimentation membrane (43) of blotter (42).
2. The simple liquid-based cytology production assembly of claim 1, wherein the filter head (3) comprises a filter cover (31) detachably connected to the cup body (1), the filter cover (31) is provided with a filter layer (32), and the filter cover (31) is provided with a filter hole (311) communicating with the inside of the cup body (1).
3. A simple assembly for preparing a liquid-based cytology specimen according to claim 1 wherein a removable filter cartridge (5) is disposed between the filter head (3) and the specimen preparing head (4), and at least one filter (51) is disposed on the filter cartridge (5).
4. The simple liquid-based cytology production assembly of claim 1, wherein the inner cavity (11) of the cup body (1) is a conical cavity and the bottom (21) of the filter cup (2) is a flat filter screen.
5. The simple liquid-based cytology production assembly of claim 4, wherein the outer periphery (12) of the cup body (1) is cylindrical and the bottom end surface (13) of the cup body (1) is flat.
6. A simplified liquid-based cytology production assembly according to claim 1 wherein the inner peripheral wall of the filter cup (2) is provided with radially extending grooves (22).
7. A simplified liquid-based cytology preparation assembly according to claim 6 wherein the recess (22) is annular.
8. A simple assembly for preparing liquid-based cell as claimed in claim 6, wherein said recess (22) is a multi-segment arc-shaped groove, and is circumferentially distributed on the same radial plane.
CN201721580108.8U 2017-11-22 2017-11-22 Simple liquid-based cell slide-making assembly Active CN210741954U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111849710A (en) * 2020-08-12 2020-10-30 泰州鑫联诚润生物技术有限公司 Cytology DNA detects sample preservative fluid preprocessing device
CN113252765A (en) * 2021-06-21 2021-08-13 南昌大学 Capillary electrophoresis instrument
CN115950709A (en) * 2023-02-10 2023-04-11 南京九川科学技术有限公司 A liquid-based thin-layer cell film production tube and an integrated film production system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111849710A (en) * 2020-08-12 2020-10-30 泰州鑫联诚润生物技术有限公司 Cytology DNA detects sample preservative fluid preprocessing device
CN113252765A (en) * 2021-06-21 2021-08-13 南昌大学 Capillary electrophoresis instrument
CN115950709A (en) * 2023-02-10 2023-04-11 南京九川科学技术有限公司 A liquid-based thin-layer cell film production tube and an integrated film production system

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